Features Interactions Isoform Disease Linear motifs Fingerprint Network All partners

RAB10_HUMAN

(Microbial infection) Upon Legionella pneumophila infection promotes endoplasmic reticulum recruitment and bacterial replication. Plays a role in remodeling the Legionella-containing vacuole (LCV) into an endoplasmic reticulum-like vacuole. [View more on UniProt]

To display all evidence describing the interaction with a partner, click on the protein name left to the bars.

Download full PS network for entry.

No data found.

No data found.

No annotated instance was found. To search for linear motifs, use the ELM prediction server.

Molecular function

Term Name % Distance from the top of the tree Annotated in RAB10_HUMAN
GO:0017076 purine nucleotide binding 30.5882 4 yes
GO:0032555 purine ribonucleotide binding 30.5882 4 yes
GO:0035639 purine ribonucleoside triphosphate binding 30.5882 4 yes
GO:0016462 pyrophosphatase activity 22.3529 5 yes
GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 22.3529 4 yes
GO:0017111 ribonucleoside triphosphate phosphatase activity 22.3529 6 yes
GO:0019900 kinase binding 22.3529 4 no
GO:0019901 protein kinase binding 21.1765 5 no
GO:0046872 metal ion binding 21.1765 4 no
GO:0003924 GTPase activity 20.0000 7 yes
GO:0005525 GTP binding 20.0000 5 yes
GO:0019001 guanyl nucleotide binding 20.0000 5 yes
GO:0032561 guanyl ribonucleotide binding 20.0000 5 yes
GO:0019003 GDP binding 15.2941 4 yes
GO:0045296 cadherin binding 10.5882 4 yes
GO:0017022 myosin binding 7.0588 4 yes
GO:0031489 myosin V binding 5.8824 5 yes
GO:0098631 cell adhesion mediator activity 4.7059 4 yes
GO:0098632 cell-cell adhesion mediator activity 3.5294 5 yes
GO:0098641 cadherin binding involved in cell-cell adhesion 2.3529 5 yes

Biological process

Term Name % Distance from top the of the tree Annotated in RAB10_HUMAN
GO:0008104 protein localization 58.8235 4 yes
GO:0048522 positive regulation of cellular process 52.9412 4 no
GO:0071702 organic substance transport 47.0588 4 yes
GO:0071705 nitrogen compound transport 47.0588 4 yes
GO:0015031 protein transport 45.8824 4 yes
GO:0016192 vesicle-mediated transport 45.8824 4 yes
GO:0048523 negative regulation of cellular process 45.8824 4 no
GO:0006996 organelle organization 43.5294 4 yes
GO:0031323 regulation of cellular metabolic process 40.0000 4 no
GO:0060255 regulation of macromolecule metabolic process 40.0000 4 no
GO:0080090 regulation of primary metabolic process 37.6471 4 no
GO:0051049 regulation of transport 36.4706 4 yes
GO:0009893 positive regulation of metabolic process 36.4706 4 no
GO:0051171 regulation of nitrogen compound metabolic process 36.4706 4 no
GO:0010604 positive regulation of macromolecule metabolic process 35.2941 5 no
GO:0010646 regulation of cell communication 35.2941 4 no
GO:0051246 regulation of protein metabolic process 32.9412 5 no
GO:0051128 regulation of cellular component organization 32.9412 4 no
GO:0022607 cellular component assembly 30.5882 4 no
GO:0009966 regulation of signal transduction 30.5882 4 no
GO:0051173 positive regulation of nitrogen compound metabolic process 29.4118 5 no
GO:0046903 secretion 28.2353 4 yes
GO:0051247 positive regulation of protein metabolic process 27.0588 6 no
GO:0010941 regulation of cell death 27.0588 4 no
GO:0009892 negative regulation of metabolic process 25.8824 4 no
GO:0031325 positive regulation of cellular metabolic process 25.8824 5 no
GO:0042981 regulation of apoptotic process 25.8824 6 no
GO:0043067 regulation of programmed cell death 25.8824 5 no
GO:0010468 regulation of gene expression 25.8824 5 no
GO:0033365 protein localization to organelle 24.7059 5 yes
GO:0010605 negative regulation of macromolecule metabolic process 24.7059 5 no
GO:0072657 protein localization to membrane 23.5294 4 yes
GO:0051172 negative regulation of nitrogen compound metabolic process 23.5294 5 no
GO:0006886 intracellular protein transport 23.5294 4 no
GO:0010243 response to organonitrogen compound 22.3529 4 yes
GO:0030030 cell projection organization 22.3529 4 yes
GO:0031324 negative regulation of cellular metabolic process 22.3529 5 no
GO:1902531 regulation of intracellular signal transduction 22.3529 5 no
GO:0032880 regulation of protein localization 22.3529 5 no
GO:0060341 regulation of cellular localization 22.3529 4 no
GO:0006887 exocytosis 21.1765 4 yes
GO:0060627 regulation of vesicle-mediated transport 21.1765 4 yes
GO:0071310 cellular response to organic substance 21.1765 4 yes
GO:0031399 regulation of protein modification process 21.1765 6 no
GO:0051046 regulation of secretion 20.0000 5 yes
GO:1903530 regulation of secretion by cell 20.0000 4 yes
GO:1990778 protein localization to cell periphery 18.8235 5 yes
GO:0098876 vesicle-mediated transport to the plasma membrane 16.4706 4 yes
GO:1901701 cellular response to oxygen-containing compound 16.4706 4 yes
GO:0048193 Golgi vesicle transport 15.2941 5 yes
GO:0072659 protein localization to plasma membrane 15.2941 5 yes
GO:0017157 regulation of exocytosis 14.1176 5 yes
GO:0072594 establishment of protein localization to organelle 14.1176 4 yes
GO:0006892 post-Golgi vesicle-mediated transport 12.9412 6 yes
GO:0016197 endosomal transport 11.7647 4 yes
GO:0048278 vesicle docking 11.7647 4 yes
GO:0071417 cellular response to organonitrogen compound 11.7647 4 yes
GO:1901652 response to peptide 11.7647 4 yes
GO:1901699 cellular response to nitrogen compound 11.7647 4 yes
GO:0006893 Golgi to plasma membrane transport 10.5882 5 yes
GO:0009306 protein secretion 10.5882 4 yes
GO:0035592 establishment of protein localization to extracellular region 10.5882 4 yes
GO:0043434 response to peptide hormone 10.5882 4 yes
GO:0071692 protein localization to extracellular region 10.5882 5 yes
GO:0090150 establishment of protein localization to membrane 10.5882 4 yes
GO:0032868 response to insulin 9.4118 5 yes
GO:0032870 cellular response to hormone stimulus 9.4118 4 yes
GO:1901653 cellular response to peptide 9.4118 5 yes
GO:0032869 cellular response to insulin stimulus 8.2353 6 yes
GO:0032990 cell part morphogenesis 8.2353 4 yes
GO:0048812 neuron projection morphogenesis 8.2353 7 yes
GO:0048858 cell projection morphogenesis 8.2353 5 yes
GO:0071375 cellular response to peptide hormone stimulus 8.2353 5 yes
GO:0120039 plasma membrane bounded cell projection morphogenesis 8.2353 6 yes
GO:0007409 axonogenesis 5.8824 8 yes
GO:0061951 establishment of protein localization to plasma membrane 5.8824 5 yes
GO:0070972 protein localization to endoplasmic reticulum 5.8824 6 yes
GO:0045055 regulated exocytosis 4.7059 5 yes
GO:0072599 establishment of protein localization to endoplasmic reticulum 4.7059 5 yes
GO:0007029 endoplasmic reticulum organization 3.5294 5 yes
GO:0030855 epithelial cell differentiation 3.5294 4 yes
GO:0071786 endoplasmic reticulum tubular network organization 3.5294 6 yes
GO:0030859 polarized epithelial cell differentiation 2.3529 5 yes
GO:0043001 Golgi to plasma membrane protein transport 2.3529 5 yes
GO:0045200 establishment of neuroblast polarity 2.3529 4 yes
GO:0097051 establishment of protein localization to endoplasmic reticulum membrane 2.3529 5 yes
GO:1903361 protein localization to basolateral plasma membrane 2.3529 5 yes

Disease

Term Name % Distance from top the of the tree Annotated in RAB10_HUMAN
DOID:0050700 cardiomyopathy 3.5294 4 no
DOID:0060036 intrinsic cardiomyopathy 3.5294 5 no
DOID:114 heart disease 3.5294 3 no
DOID:2843 long QT syndrome 2.3529 6 no
DOID:0050539 Charcot-Marie-Tooth disease type 2 2.3529 7 no
DOID:10595 Charcot-Marie-Tooth disease 2.3529 6 no
DOID:440 neuromuscular disease 2.3529 5 no
DOID:574 peripheral nervous system disease 2.3529 3 no
DOID:870 neuropathy 2.3529 4 no
Uniprot ID Details Highest evidence Localizing into PSD HPA (protein expression in neurons)
RAB10_HUMAN [view entry] [view interactions] Low throughput yes yes
MICA2_HUMAN [view interactions] Low throughput no yes
MILK1_HUMAN [view interactions] Low throughput no yes
GDIB_HUMAN [view entry] [view interactions] Low throughput yes yes
GDIA_HUMAN [view entry] [view interactions] Low throughput yes yes
RIPL1_HUMAN [view interactions] Low throughput no yes
MSS4_HUMAN [view interactions] Low throughput no yes
DZIP1_HUMAN [view interactions] Low throughput no yes
RIPL2_HUMAN [view interactions] Low throughput no yes
PPM1H_HUMAN [view interactions] Low throughput no yes
JIP4_HUMAN [view interactions] Low throughput no yes
JIP3_HUMAN [view entry] [view interactions] Low throughput yes yes
OPTN_HUMAN [view interactions] Low throughput no yes
EMP3_HUMAN [view interactions] Low throughput no no
ECHP_HUMAN [view interactions] Low throughput no no
MICA1_HUMAN [view interactions] Low throughput no yes
EH1L1_HUMAN [view interactions] Low throughput no yes
GGA2_HUMAN [view interactions] Low throughput no yes
ITB1_HUMAN [view entry] [view interactions] Low throughput yes no
JIP1_HUMAN [view entry] [view interactions] Low throughput yes yes
KLC1_HUMAN [view entry] [view interactions] Low throughput yes no
EHBP1_HUMAN [view interactions] Low throughput no yes
CH60_HUMAN [view entry] [view interactions] Low throughput yes yes
GCR_HUMAN [view entry] [view interactions] High throughput yes yes
TRI37_HUMAN [view entry] [view interactions] High throughput yes yes
LAMP2_HUMAN [view interactions] High throughput no yes
LAMP3_HUMAN [view interactions] High throughput no no
LTOR1_HUMAN [view entry] [view interactions] High throughput yes yes
RB11A_HUMAN [view entry] [view interactions] High throughput yes yes
RHOB_HUMAN [view entry] [view interactions] High throughput yes no
TMPS2_HUMAN [view interactions] High throughput no no
TM11B_HUMAN [view interactions] High throughput no no
SYNPO_HUMAN [view entry] [view interactions] High throughput yes no
ENOPH_HUMAN [view interactions] High throughput no yes
GLUT4_HUMAN [view interactions] High throughput no no
LRRK2_HUMAN [view interactions] High throughput no yes
RAE1_HUMAN [view interactions] High throughput no yes
RAE2_HUMAN [view interactions] High throughput no yes
RAB35_HUMAN [view entry] [view interactions] High throughput yes yes
RB39A_HUMAN [view interactions] High throughput no no
RAB19_HUMAN [view interactions] High throughput no no
MICA3_HUMAN [view interactions] High throughput no yes
RAB6C_HUMAN [view interactions] High throughput no no
RAB12_HUMAN [view entry] [view interactions] High throughput yes yes
MSPD2_HUMAN [view interactions] High throughput no yes
RIN3_HUMAN [view interactions] High throughput no yes
CTBP1_HUMAN [view entry] [view interactions] High throughput yes yes
MOT11_HUMAN [view interactions] High throughput no no
MTMRE_HUMAN [view entry] [view interactions] High throughput yes yes
VCAM1_HUMAN [view interactions] High throughput no no
FINC_HUMAN [view interactions] High throughput no yes
SDHA_HUMAN [view interactions] High throughput no yes
RB33B_HUMAN [view interactions] High throughput no no
RUSD4_HUMAN [view interactions] High throughput no yes
SRCN1_HUMAN [view entry] [view interactions] High throughput yes yes
BICL2_HUMAN [view interactions] High throughput no no
HMGA2_HUMAN [view interactions] High throughput no yes
MED20_HUMAN [view interactions] High throughput no no
SHIP1_HUMAN [view interactions] High throughput no no
DGKQ_HUMAN [view entry] [view interactions] High throughput yes yes
AMZ2_HUMAN [view interactions] High throughput no yes
KS6A5_HUMAN [view entry] [view interactions] High throughput yes yes
AAPK1_HUMAN [view interactions] High throughput no no
MYLK_HUMAN [view interactions] High throughput no no
COQ8A_HUMAN [view interactions] High throughput no no
CALM2_HUMAN [view entry] [view interactions] High throughput yes yes
CALM3_HUMAN [view entry] [view interactions] High throughput yes yes
CALM1_HUMAN [view entry] [view interactions] High throughput yes yes
TRAF6_HUMAN [view interactions] High throughput no yes
AP1S1_HUMAN [view entry] [view interactions] High throughput yes yes
RAB8A_HUMAN [view entry] [view interactions] High throughput yes no
DOK2_HUMAN [view interactions] High throughput no no
MFSD1_HUMAN [view interactions] High throughput no no
AURKA_HUMAN [view entry] [view interactions] High throughput yes no
EPB41_HUMAN [view entry] [view interactions] High throughput yes no
PTBP3_HUMAN [view interactions] High throughput no no
JUN_HUMAN [view interactions] High throughput no yes
SYGP1_HUMAN [view entry] [view interactions] High throughput yes yes
DLG4_HUMAN [view entry] [view interactions] High throughput yes yes
CD177_HUMAN [view interactions] High throughput no no
CD81_HUMAN [view interactions] High throughput no no
ITM2B_HUMAN [view interactions] High throughput no yes
CNDD3_HUMAN [view interactions] High throughput no no
MTR1A_HUMAN [view interactions] High throughput no no
RAB13_HUMAN [view entry] [view interactions] High throughput yes yes
SPTCS_HUMAN [view interactions] High throughput no yes
ACTN3_HUMAN [view entry] [view interactions] High throughput yes no
HTR5B_HUMAN [view interactions] High throughput no yes
TPC6B_HUMAN [view interactions] High throughput no yes
PRI2_HUMAN [view interactions] High throughput no no
RAB3C_HUMAN [view entry] [view interactions] High throughput yes yes
RB39B_HUMAN [view interactions] High throughput no no
CC038_HUMAN [view interactions] High throughput no yes
RS24_HUMAN [view entry] [view interactions] High throughput yes yes
RAB1B_HUMAN [view entry] [view interactions] High throughput yes yes
TT30B_HUMAN [view interactions] High throughput no no
ESR1_HUMAN [view interactions] High throughput no no
RAB8B_HUMAN [view entry] [view interactions] High throughput yes no
TECT2_HUMAN [view interactions] High throughput no yes
LAMP1_HUMAN [view interactions] High throughput no yes
RASK_HUMAN [view entry] [view interactions] High throughput yes no
RASN_HUMAN [view entry] [view interactions] High throughput yes no
RASH_HUMAN [view entry] [view interactions] High throughput yes no
PGFRB_HUMAN [view interactions] High throughput no yes
CXCL7_HUMAN [view interactions] High throughput no yes
EVI5L_HUMAN [view interactions] High throughput no yes
SYTL3_HUMAN [view interactions] High throughput no no
MELPH_HUMAN [view interactions] High throughput no yes
LMNA_HUMAN [view entry] [view interactions] High throughput yes yes
ELAV1_HUMAN [view entry] [view interactions] High throughput yes yes
TERA_HUMAN [view entry] [view interactions] High throughput yes yes
UBL4A_HUMAN [view entry] [view interactions] High throughput yes yes
ITA4_HUMAN [view interactions] High throughput no no
ATP4A_HUMAN [view entry] [view interactions] High throughput yes no
RFA3_HUMAN [view interactions] High throughput no yes
RFA2_HUMAN [view interactions] High throughput no yes
RFA1_HUMAN [view interactions] High throughput no yes
ASB17_HUMAN [view interactions] High throughput no no
STAU1_HUMAN [view entry] [view interactions] High throughput yes yes
CUL7_HUMAN [view interactions] High throughput no yes
RING2_HUMAN [view interactions] High throughput no yes
RIMS1_HUMAN [view entry] [view interactions] High throughput yes yes
CDC73_HUMAN [view interactions] High throughput no yes
DUS22_HUMAN [view interactions] High throughput no yes
FACD2_HUMAN [view interactions] High throughput no no
FOXA1_HUMAN [view interactions] High throughput no no
TRI25_HUMAN [view interactions] High throughput no yes
HNRPL_HUMAN [view interactions] High throughput no yes
PPP6_HUMAN [view interactions] High throughput no yes
RNF4_HUMAN [view interactions] High throughput no yes
CHD3_HUMAN [view interactions] High throughput no yes
UB2R1_HUMAN [view interactions] High throughput no yes
ESR2_HUMAN [view interactions] High throughput no no
HEXI1_HUMAN [view interactions] High throughput no yes
SNAI1_HUMAN [view interactions] High throughput no yes
RECQ4_HUMAN [view interactions] High throughput no yes
DCPS_HUMAN [view interactions] High throughput no yes
VIR_HUMAN [view interactions] High throughput no yes
FLCN_HUMAN [view interactions] High throughput no yes
UBP14_HUMAN [view entry] [view interactions] High throughput yes yes
NR2C2_HUMAN [view interactions] High throughput no yes
GLUC_HUMAN [view interactions] High throughput no no
TAU_HUMAN [view entry] [view interactions] High throughput yes yes
BAG6_HUMAN [view entry] [view interactions] High throughput yes yes
LMBRL_HUMAN [view interactions] High throughput no no
EMC2_HUMAN [view interactions] High throughput no yes
CTRO_HUMAN [view entry] [view interactions] High throughput yes yes
ANLN_HUMAN [view interactions] High throughput no yes
KI20A_HUMAN [view interactions] High throughput no yes
KIF23_HUMAN [view interactions] High throughput no yes
CFAD_HUMAN [view interactions] High throughput no no
FNDC5_HUMAN [view interactions] High throughput no no
RBM39_HUMAN [view interactions] High throughput no yes
APR_HUMAN [view interactions] High throughput no yes
ANDR_HUMAN [view interactions] High throughput no no
DDRGK_HUMAN [view entry] [view interactions] High throughput yes yes
ZBTB2_HUMAN [view interactions] High throughput no yes
CSC1_HUMAN [view interactions] High throughput no no
BTF3_HUMAN [view interactions] High throughput no yes
NRP1_HUMAN [view entry] [view interactions] High throughput yes yes
CATL1_HUMAN [view interactions] High throughput no yes
FURIN_HUMAN [view interactions] High throughput no yes
DPP4_HUMAN [view interactions] High throughput no no
BASI_HUMAN [view entry] [view interactions] High throughput yes no
CLC4D_HUMAN [view interactions] High throughput no no
ACE2_HUMAN [view interactions] High throughput no no
TMPS4_HUMAN [view interactions] High throughput no yes
CLC4E_HUMAN [view interactions] High throughput no no
ANTR1_HUMAN [view interactions] High throughput no no
CLU_HUMAN [view interactions] High throughput no yes
OST4_HUMAN [view interactions] High throughput no no
TOM40_HUMAN [view interactions] High throughput no yes
RTN4_HUMAN [view entry] [view interactions] High throughput yes yes
TMEDA_HUMAN [view interactions] High throughput no yes
EIPR1_HUMAN [view interactions] High throughput no yes
FAS_HUMAN [view entry] [view interactions] High throughput yes no
EGFR_HUMAN [view interactions] High throughput no no
A4_HUMAN [view entry] [view interactions] High throughput yes yes
FACE1_HUMAN [view interactions] High throughput no yes
COF1_HUMAN [view entry] [view interactions] High throughput yes no
G6PI_HUMAN [view entry] [view interactions] High throughput yes yes
LEG1_HUMAN [view interactions] High throughput no yes
PPIA_HUMAN [view entry] [view interactions] High throughput yes yes
FKBP2_HUMAN [view interactions] High throughput no yes
FUBP3_HUMAN [view interactions] High throughput no yes
ROA3_HUMAN [view entry] [view interactions] High throughput yes yes
M3K15_HUMAN [view interactions] High throughput no no
MDHM_HUMAN [view entry] [view interactions] High throughput yes yes
KPYM_HUMAN [view interactions] High throughput no yes
TAGL2_HUMAN [view entry] [view interactions] High throughput yes no
TKT_HUMAN [view entry] [view interactions] High throughput yes yes
UB2L3_HUMAN [view interactions] High throughput no yes
RAB5C_HUMAN [view entry] [view interactions] High throughput yes yes
RAB7A_HUMAN [view entry] [view interactions] High throughput yes yes
TIAR_HUMAN [view interactions] High throughput no no
QCR2_HUMAN [view entry] [view interactions] High throughput yes yes
SEPT9_HUMAN [view interactions] High throughput no no
CADH1_HUMAN [view entry] [view interactions] High throughput yes no
AGR2_HUMAN [view interactions] High throughput no no
RFFL_HUMAN [view interactions] High throughput no yes
MTG2_HUMAN [view interactions] High throughput no yes
LCAP_HUMAN [view interactions] Computational no yes
SNP23_HUMAN [view entry] [view interactions] Computational yes no
DEN4C_HUMAN [view interactions] Computational no yes
EXOC2_HUMAN [view entry] [view interactions] Computational yes no
EXOC8_HUMAN [view entry] [view interactions] Computational yes yes
MYO5A_HUMAN [view entry] [view interactions] Computational yes yes
TBCD4_HUMAN [view interactions] Computational no yes
EXOC7_HUMAN [view entry] [view interactions] Computational yes yes
DEN4B_HUMAN [view interactions] Computational no yes
STX4_HUMAN [view entry] [view interactions] Computational yes no
EXOC5_HUMAN [view entry] [view interactions] Computational yes yes
EXC6B_HUMAN [view entry] [view interactions] Computational yes yes
EXOC3_HUMAN [view entry] [view interactions] Computational yes no
EXOC6_HUMAN [view entry] [view interactions] Computational yes yes
STXB3_HUMAN [view entry] [view interactions] Computational yes yes
CALX_HUMAN [view entry] [view interactions] Computational yes yes
RAB3I_HUMAN [view interactions] Computational no no
EXOC1_HUMAN [view entry] [view interactions] Computational yes yes
TBCD1_HUMAN [view interactions] Computational no no
MYO5B_HUMAN [view entry] [view interactions] Computational yes yes
MARCS_HUMAN [view entry] [view interactions] Computational yes yes
EXOC4_HUMAN [view entry] [view interactions] Computational yes yes
RALA_HUMAN [view entry] [view interactions] Computational yes yes