Features Interactions Isoform Disease Linear motifs Fingerprint Network All partners

RAB10_HUMAN

(Microbial infection) Upon Legionella pneumophila infection promotes endoplasmic reticulum recruitment and bacterial replication. Plays a role in remodeling the Legionella-containing vacuole (LCV) into an endoplasmic reticulum-like vacuole. [View more on UniProt]

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No data found.

No data found.

No annotated instance was found. To search for linear motifs, use the ELM prediction server.

Molecular function

Term Name % Distance from the top of the tree Annotated in RAB10_HUMAN
GO:0043168 anion binding 36.5854 4 yes
GO:0000166 nucleotide binding 35.3659 4 yes
GO:0017076 purine nucleotide binding 35.3659 5 yes
GO:0032555 purine ribonucleotide binding 34.1463 4 yes
GO:0035639 purine ribonucleoside triphosphate binding 32.9268 4 yes
GO:0043169 cation binding 32.9268 4 no
GO:0046872 metal ion binding 32.9268 5 no
GO:0016462 pyrophosphatase activity 25.6098 5 yes
GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 25.6098 4 yes
GO:0017111 ribonucleoside triphosphate phosphatase activity 25.6098 6 yes
GO:0019900 kinase binding 25.6098 4 no
GO:0019901 protein kinase binding 21.9512 5 no
GO:0003924 GTPase activity 19.5122 7 yes
GO:0005525 GTP binding 19.5122 5 yes
GO:0019001 guanyl nucleotide binding 19.5122 6 yes
GO:0032561 guanyl ribonucleotide binding 19.5122 5 yes
GO:0019003 GDP binding 14.6341 5 yes
GO:0045296 cadherin binding 12.1951 4 yes
GO:0017022 myosin binding 6.0976 4 yes
GO:0031489 myosin V binding 6.0976 5 yes
GO:0098631 cell adhesion mediator activity 3.6585 4 yes
GO:0098632 cell-cell adhesion mediator activity 2.4390 5 yes
GO:0098641 cadherin binding involved in cell-cell adhesion 2.4390 5 yes

Biological process

Term Name % Distance from top the of the tree Annotated in RAB10_HUMAN
GO:0048522 positive regulation of cellular process 60.9756 4 no
GO:0048523 negative regulation of cellular process 56.0976 4 no
GO:0008104 protein localization 50.0000 4 yes
GO:0060255 regulation of macromolecule metabolic process 50.0000 4 no
GO:0006996 organelle organization 45.1220 4 yes
GO:0010646 regulation of cell communication 45.1220 4 no
GO:0031323 regulation of cellular metabolic process 45.1220 4 no
GO:0080090 regulation of primary metabolic process 45.1220 4 no
GO:0009893 positive regulation of metabolic process 42.6829 4 no
GO:0010604 positive regulation of macromolecule metabolic process 41.4634 5 no
GO:0051128 regulation of cellular component organization 41.4634 4 no
GO:0009966 regulation of signal transduction 39.0244 4 no
GO:0022607 cellular component assembly 36.5854 4 no
GO:0051246 regulation of protein metabolic process 36.5854 5 no
GO:0009889 regulation of biosynthetic process 35.3659 4 no
GO:0031325 positive regulation of cellular metabolic process 35.3659 5 no
GO:0051049 regulation of transport 35.3659 4 no
GO:0071702 organic substance transport 34.1463 4 yes
GO:0071705 nitrogen compound transport 34.1463 4 yes
GO:0009892 negative regulation of metabolic process 34.1463 4 no
GO:0010468 regulation of gene expression 34.1463 6 no
GO:0010556 regulation of macromolecule biosynthetic process 34.1463 5 no
GO:0031326 regulation of cellular biosynthetic process 34.1463 5 no
GO:0010605 negative regulation of macromolecule metabolic process 32.9268 5 no
GO:0015031 protein transport 31.7073 4 yes
GO:0051247 positive regulation of protein metabolic process 31.7073 6 no
GO:0042981 regulation of apoptotic process 30.4878 5 no
GO:0043067 regulation of programmed cell death 30.4878 4 no
GO:1902531 regulation of intracellular signal transduction 30.4878 5 no
GO:0031324 negative regulation of cellular metabolic process 30.4878 5 no
GO:0048584 positive regulation of response to stimulus 29.2683 4 no
GO:0010647 positive regulation of cell communication 26.8293 5 no
GO:0023056 positive regulation of signaling 26.8293 4 no
GO:0033365 protein localization to organelle 25.6098 5 yes
GO:0019219 regulation of nucleobase-containing compound metabolic process 25.6098 5 no
GO:0031399 regulation of protein modification process 25.6098 6 no
GO:0009891 positive regulation of biosynthetic process 24.3902 5 no
GO:0019220 regulation of phosphate metabolic process 24.3902 6 no
GO:0043933 protein-containing complex organization 24.3902 4 no
GO:0051174 regulation of phosphorus metabolic process 24.3902 5 no
GO:0060341 regulation of cellular localization 24.3902 4 no
GO:0030030 cell projection organization 23.1707 4 yes
GO:0009967 positive regulation of signal transduction 23.1707 5 no
GO:0031328 positive regulation of cellular biosynthetic process 23.1707 6 no
GO:0031401 positive regulation of protein modification process 23.1707 7 no
GO:0036211 protein modification process 23.1707 4 no
GO:0043066 negative regulation of apoptotic process 23.1707 6 no
GO:0043069 negative regulation of programmed cell death 23.1707 5 no
GO:0043412 macromolecule modification 23.1707 4 no
GO:0032880 regulation of protein localization 23.1707 5 no
GO:0010557 positive regulation of macromolecule biosynthetic process 21.9512 6 no
GO:0042325 regulation of phosphorylation 21.9512 7 no
GO:0051252 regulation of RNA metabolic process 21.9512 5 no
GO:0141124 intracellular signaling cassette 21.9512 4 no
GO:0009890 negative regulation of biosynthetic process 21.9512 5 no
GO:0010558 negative regulation of macromolecule biosynthetic process 21.9512 6 no
GO:0031327 negative regulation of cellular biosynthetic process 21.9512 6 no
GO:0001932 regulation of protein phosphorylation 20.7317 7 no
GO:0006355 regulation of DNA-templated transcription 20.7317 7 no
GO:0010562 positive regulation of phosphorus metabolic process 20.7317 6 no
GO:0044087 regulation of cellular component biogenesis 20.7317 4 no
GO:0045937 positive regulation of phosphate metabolic process 20.7317 7 no
GO:0051129 negative regulation of cellular component organization 20.7317 5 no
GO:2001141 regulation of RNA biosynthetic process 20.7317 6 no
GO:0080134 regulation of response to stress 20.7317 4 no
GO:0072657 protein localization to membrane 19.5122 4 yes
GO:0071310 cellular response to organic substance 18.2927 4 yes
GO:0046903 secretion 15.8537 4 yes
GO:0072594 establishment of protein localization to organelle 15.8537 4 yes
GO:1901701 cellular response to oxygen-containing compound 15.8537 4 yes
GO:0010243 response to organonitrogen compound 14.6341 4 yes
GO:1990778 protein localization to cell periphery 14.6341 5 yes
GO:0072659 protein localization to plasma membrane 13.4146 5 yes
GO:0048812 neuron projection morphogenesis 9.7561 5 yes
GO:0071417 cellular response to organonitrogen compound 9.7561 4 yes
GO:0090150 establishment of protein localization to membrane 9.7561 4 yes
GO:0120039 plasma membrane bounded cell projection morphogenesis 9.7561 4 yes
GO:1901699 cellular response to nitrogen compound 9.7561 4 yes
GO:0007409 axonogenesis 7.3171 6 yes
GO:0032870 cellular response to hormone stimulus 7.3171 4 yes
GO:0043434 response to peptide hormone 6.0976 4 yes
GO:0061951 establishment of protein localization to plasma membrane 6.0976 5 yes
GO:0070972 protein localization to endoplasmic reticulum 6.0976 6 yes
GO:0030855 epithelial cell differentiation 4.8780 4 yes
GO:0032868 response to insulin 4.8780 5 yes
GO:0032869 cellular response to insulin stimulus 4.8780 6 yes
GO:0045055 regulated exocytosis 4.8780 4 yes
GO:0071375 cellular response to peptide hormone stimulus 4.8780 5 yes
GO:0072599 establishment of protein localization to endoplasmic reticulum 4.8780 5 yes
GO:0006892 post-Golgi vesicle-mediated transport 3.6585 4 yes
GO:0007029 endoplasmic reticulum organization 3.6585 5 yes
GO:0071786 endoplasmic reticulum tubular network organization 3.6585 6 yes
GO:0006893 Golgi to plasma membrane transport 2.4390 4 yes
GO:0030859 polarized epithelial cell differentiation 2.4390 5 yes
GO:0043001 Golgi to plasma membrane protein transport 2.4390 5 yes
GO:0045200 establishment of neuroblast polarity 2.4390 4 yes
GO:0097051 establishment of protein localization to endoplasmic reticulum membrane 2.4390 5 yes
GO:1903361 protein localization to basolateral plasma membrane 2.4390 5 yes

Disease

No data found.

Uniprot ID Details Highest evidence Localizing into PSD HPA (protein expression in neurons)
PPM1H_HUMAN [view interactions] Low throughput no yes
JIP4_HUMAN [view interactions] Low throughput no yes
JIP3_HUMAN [view entry] [view interactions] Low throughput yes yes
OPTN_HUMAN [view interactions] Low throughput no yes
EMP3_HUMAN [view interactions] Low throughput no no
ECHP_HUMAN [view interactions] Low throughput no no
MICA1_HUMAN [view interactions] Low throughput no yes
EH1L1_HUMAN [view interactions] Low throughput no yes
GGA2_HUMAN [view interactions] Low throughput no yes
ITB1_HUMAN [view entry] [view interactions] Low throughput yes no
JIP1_HUMAN [view entry] [view interactions] Low throughput yes yes
KLC1_HUMAN [view entry] [view interactions] Low throughput yes no
EHBP1_HUMAN [view interactions] Low throughput no yes
CH60_HUMAN [view entry] [view interactions] Low throughput yes yes
RAB10_HUMAN [view entry] [view interactions] Low throughput yes yes
MICA2_HUMAN [view interactions] Low throughput no yes
MILK1_HUMAN [view interactions] Low throughput no yes
GDIA_HUMAN [view entry] [view interactions] Low throughput yes yes
GDIB_HUMAN [view entry] [view interactions] Low throughput yes yes
MSS4_HUMAN [view interactions] Low throughput no yes
RIPL1_HUMAN [view interactions] Low throughput no yes
DZIP1_HUMAN [view interactions] Low throughput no yes
RIPL2_HUMAN [view interactions] Low throughput no yes
MSPD2_HUMAN [view interactions] High throughput no yes
RIN3_HUMAN [view interactions] High throughput no yes
CTBP1_HUMAN [view entry] [view interactions] High throughput yes yes
MOT11_HUMAN [view interactions] High throughput no no
MTMRE_HUMAN [view entry] [view interactions] High throughput yes yes
VCAM1_HUMAN [view interactions] High throughput no no
FINC_HUMAN [view interactions] High throughput no yes
SDHA_HUMAN [view interactions] High throughput no yes
RB33B_HUMAN [view interactions] High throughput no no
RUSD4_HUMAN [view interactions] High throughput no yes
SRCN1_HUMAN [view entry] [view interactions] High throughput yes yes
BICL2_HUMAN [view interactions] High throughput no no
HMGA2_HUMAN [view interactions] High throughput no yes
MED20_HUMAN [view interactions] High throughput no no
SHIP1_HUMAN [view interactions] High throughput no no
AMZ2_HUMAN [view interactions] High throughput no yes
DGKQ_HUMAN [view entry] [view interactions] High throughput yes yes
KS6A5_HUMAN [view entry] [view interactions] High throughput yes yes
AAPK1_HUMAN [view interactions] High throughput no no
MYLK_HUMAN [view entry] [view interactions] High throughput yes no
COQ8A_HUMAN [view interactions] High throughput no no
CALM3_HUMAN [view entry] [view interactions] High throughput yes yes
TRAF6_HUMAN [view entry] [view interactions] High throughput yes yes
AP1S1_HUMAN [view entry] [view interactions] High throughput yes yes
RAB8A_HUMAN [view entry] [view interactions] High throughput yes no
DOK2_HUMAN [view interactions] High throughput no no
MFSD1_HUMAN [view interactions] High throughput no no
AURKA_HUMAN [view entry] [view interactions] High throughput yes no
EPB41_HUMAN [view entry] [view interactions] High throughput yes no
PTBP3_HUMAN [view interactions] High throughput no no
JUN_HUMAN [view interactions] High throughput no yes
SYGP1_HUMAN [view entry] [view interactions] High throughput yes yes
DLG4_HUMAN [view entry] [view interactions] High throughput yes yes
CD177_HUMAN [view interactions] High throughput no no
CD81_HUMAN [view interactions] High throughput no no
ITM2B_HUMAN [view interactions] High throughput no yes
CNDD3_HUMAN [view interactions] High throughput no no
CAC1C_HUMAN [view entry] [view interactions] High throughput yes no
HCN1_HUMAN [view entry] [view interactions] High throughput yes yes
DYR1A_HUMAN [view interactions] High throughput no yes
CK5P2_HUMAN [view interactions] High throughput no yes
CEP63_HUMAN [view interactions] High throughput no yes
CE170_HUMAN [view interactions] High throughput no yes
POC5_HUMAN [view interactions] High throughput no yes
MTR1A_HUMAN [view interactions] High throughput no no
RS24_HUMAN [view entry] [view interactions] High throughput yes yes
CC038_HUMAN [view interactions] High throughput no yes
RB39B_HUMAN [view interactions] High throughput no no
RAB3C_HUMAN [view entry] [view interactions] High throughput yes yes
RAB13_HUMAN [view entry] [view interactions] High throughput yes yes
PRI2_HUMAN [view interactions] High throughput no no
TPC6B_HUMAN [view interactions] High throughput no yes
HTR5B_HUMAN [view interactions] High throughput no yes
ACTN3_HUMAN [view entry] [view interactions] High throughput yes no
SPTCS_HUMAN [view interactions] High throughput no yes
RAB1B_HUMAN [view entry] [view interactions] High throughput yes yes
IT70B_HUMAN [view interactions] High throughput no no
ESR1_HUMAN [view interactions] High throughput no no
RAB8B_HUMAN [view entry] [view interactions] High throughput yes no
TECT2_HUMAN [view interactions] High throughput no yes
LAMP1_HUMAN [view entry] [view interactions] High throughput yes yes
RASK_HUMAN [view entry] [view interactions] High throughput yes no
RASN_HUMAN [view entry] [view interactions] High throughput yes no
RASH_HUMAN [view entry] [view interactions] High throughput yes no
PGFRB_HUMAN [view interactions] High throughput no yes
CFTR_HUMAN [view interactions] High throughput no no
CXCL7_HUMAN [view interactions] High throughput no yes
EVI5L_HUMAN [view interactions] High throughput no yes
SYTL3_HUMAN [view interactions] High throughput no no
MELPH_HUMAN [view interactions] High throughput no yes
LMNA_HUMAN [view entry] [view interactions] High throughput yes yes
ELAV1_HUMAN [view entry] [view interactions] High throughput yes yes
TERA_HUMAN [view entry] [view interactions] High throughput yes yes
UBL4A_HUMAN [view entry] [view interactions] High throughput yes yes
ITA4_HUMAN [view interactions] High throughput no no
CALM2_HUMAN [view entry] [view interactions] High throughput yes yes
CALM1_HUMAN [view entry] [view interactions] High throughput yes yes
ATP4A_HUMAN [view entry] [view interactions] High throughput yes no
RFA3_HUMAN [view interactions] High throughput no yes
RFA2_HUMAN [view interactions] High throughput no yes
RFA1_HUMAN [view interactions] High throughput no yes
ASB17_HUMAN [view interactions] High throughput no no
STAU1_HUMAN [view entry] [view interactions] High throughput yes yes
CUL7_HUMAN [view interactions] High throughput no yes
RING2_HUMAN [view interactions] High throughput no yes
RIMS1_HUMAN [view entry] [view interactions] High throughput yes yes
CDC73_HUMAN [view interactions] High throughput no yes
DUS22_HUMAN [view interactions] High throughput no yes
FACD2_HUMAN [view interactions] High throughput no no
FOXA1_HUMAN [view interactions] High throughput no no
TRI25_HUMAN [view interactions] High throughput no yes
HNRPL_HUMAN [view interactions] High throughput no yes
PPP6_HUMAN [view interactions] High throughput no yes
RNF4_HUMAN [view interactions] High throughput no yes
CHD3_HUMAN [view interactions] High throughput no yes
UB2R1_HUMAN [view interactions] High throughput no yes
ESR2_HUMAN [view interactions] High throughput no no
HEXI1_HUMAN [view interactions] High throughput no yes
SNAI1_HUMAN [view interactions] High throughput no yes
RECQ4_HUMAN [view interactions] High throughput no yes
DCPS_HUMAN [view interactions] High throughput no yes
VIR_HUMAN [view interactions] High throughput no yes
FLCN_HUMAN [view interactions] High throughput no yes
UBP14_HUMAN [view entry] [view interactions] High throughput yes yes
NR2C2_HUMAN [view interactions] High throughput no yes
GLUC_HUMAN [view interactions] High throughput no no
TAU_HUMAN [view entry] [view interactions] High throughput yes yes
BAG6_HUMAN [view entry] [view interactions] High throughput yes yes
LMBRL_HUMAN [view interactions] High throughput no no
EMC2_HUMAN [view interactions] High throughput no yes
CTRO_HUMAN [view entry] [view interactions] High throughput yes yes
ANLN_HUMAN [view interactions] High throughput no yes
KI20A_HUMAN [view interactions] High throughput no yes
KIF23_HUMAN [view interactions] High throughput no yes
CFAD_HUMAN [view interactions] High throughput no no
FNDC5_HUMAN [view interactions] High throughput no no
RBM39_HUMAN [view interactions] High throughput no yes
APR_HUMAN [view interactions] High throughput no yes
ANDR_HUMAN [view interactions] High throughput no no
DDRGK_HUMAN [view entry] [view interactions] High throughput yes yes
ZBTB2_HUMAN [view interactions] High throughput no yes
CSC1_HUMAN [view interactions] High throughput no no
BTF3_HUMAN [view interactions] High throughput no yes
NRP1_HUMAN [view entry] [view interactions] High throughput yes yes
CATL1_HUMAN [view interactions] High throughput no yes
FURIN_HUMAN [view interactions] High throughput no yes
DPP4_HUMAN [view interactions] High throughput no no
BASI_HUMAN [view entry] [view interactions] High throughput yes no
CLC4D_HUMAN [view interactions] High throughput no no
ACE2_HUMAN [view interactions] High throughput no no
TMPS4_HUMAN [view interactions] High throughput no yes
CLC4E_HUMAN [view interactions] High throughput no no
ANTR1_HUMAN [view interactions] High throughput no no
CLU_HUMAN [view interactions] High throughput no yes
SOX2_HUMAN [view interactions] High throughput no yes
OST4_HUMAN [view interactions] High throughput no no
TOM40_HUMAN [view interactions] High throughput no yes
RTN4_HUMAN [view entry] [view interactions] High throughput yes yes
TMEDA_HUMAN [view interactions] High throughput no yes
SMUF1_HUMAN [view interactions] High throughput no yes
MYC_HUMAN [view interactions] High throughput no yes
CUL3_HUMAN [view entry] [view interactions] High throughput yes yes
E2F4_HUMAN [view interactions] High throughput no no
PRKN_HUMAN [view entry] [view interactions] High throughput yes yes
HDAC6_HUMAN [view interactions] High throughput no yes
ZRAN1_HUMAN [view interactions] High throughput no yes
BAP1_HUMAN [view interactions] High throughput no yes
HSP7C_HUMAN [view entry] [view interactions] High throughput yes yes
BIP_HUMAN [view entry] [view interactions] High throughput yes yes
PAQR2_HUMAN [view interactions] High throughput no yes
PARPT_HUMAN [view interactions] High throughput no no
RAF1_HUMAN [view entry] [view interactions] High throughput yes no
TRI67_HUMAN [view interactions] High throughput no no
PRRT2_HUMAN [view entry] [view interactions] High throughput yes no
PJA2_HUMAN [view entry] [view interactions] High throughput yes yes
MOB3C_HUMAN [view interactions] High throughput no no
EZH2_HUMAN [view interactions] High throughput no no
PD1L1_HUMAN [view interactions] High throughput no no
SPOP_HUMAN [view interactions] High throughput no no
GOLI_HUMAN [view interactions] High throughput no yes
RN149_HUMAN [view interactions] High throughput no no
UBE2H_HUMAN [view interactions] High throughput no yes
TNIP1_HUMAN [view interactions] High throughput no yes
EIPR1_HUMAN [view interactions] High throughput no yes
FAS_HUMAN [view entry] [view interactions] High throughput yes no
EGFR_HUMAN [view interactions] High throughput no no
A4_HUMAN [view entry] [view interactions] High throughput yes yes
FACE1_HUMAN [view interactions] High throughput no yes
COF1_HUMAN [view entry] [view interactions] High throughput yes no
G6PI_HUMAN [view entry] [view interactions] High throughput yes yes
LEG1_HUMAN [view interactions] High throughput no yes
PPIA_HUMAN [view entry] [view interactions] High throughput yes yes
FKBP2_HUMAN [view interactions] High throughput no yes
FUBP3_HUMAN [view interactions] High throughput no yes
ROA3_HUMAN [view entry] [view interactions] High throughput yes yes
M3K15_HUMAN [view interactions] High throughput no no
MDHM_HUMAN [view entry] [view interactions] High throughput yes yes
KPYM_HUMAN [view interactions] High throughput no yes
TAGL2_HUMAN [view entry] [view interactions] High throughput yes no
TKT_HUMAN [view entry] [view interactions] High throughput yes yes
UB2L3_HUMAN [view interactions] High throughput no yes
RAB5C_HUMAN [view entry] [view interactions] High throughput yes yes
RAB7A_HUMAN [view entry] [view interactions] High throughput yes yes
TIAR_HUMAN [view interactions] High throughput no no
QCR2_HUMAN [view entry] [view interactions] High throughput yes yes
SEPT9_HUMAN [view interactions] High throughput no no
RBP2_HUMAN [view interactions] High throughput no yes
CADH1_HUMAN [view entry] [view interactions] High throughput yes no
AGR2_HUMAN [view interactions] High throughput no no
RFFL_HUMAN [view interactions] High throughput no yes
MTG2_HUMAN [view interactions] High throughput no yes
GCR_HUMAN [view entry] [view interactions] High throughput yes yes
TRI37_HUMAN [view entry] [view interactions] High throughput yes yes
LAMP2_HUMAN [view interactions] High throughput no yes
LAMP3_HUMAN [view interactions] High throughput no no
LTOR1_HUMAN [view entry] [view interactions] High throughput yes yes
RB11A_HUMAN [view entry] [view interactions] High throughput yes yes
RHOB_HUMAN [view entry] [view interactions] High throughput yes no
TMPS2_HUMAN [view interactions] High throughput no no
TM11B_HUMAN [view interactions] High throughput no no
STING_HUMAN [view interactions] High throughput no yes
SYUA_HUMAN [view entry] [view interactions] High throughput yes no
PHOCN_HUMAN [view entry] [view interactions] High throughput yes yes
FBW1A_HUMAN [view interactions] High throughput no yes
DCAF4_HUMAN [view interactions] High throughput no yes
TLE2_HUMAN [view interactions] High throughput no yes
TEX2_HUMAN [view interactions] High throughput no yes
SYNPO_HUMAN [view entry] [view interactions] High throughput yes no
ENOPH_HUMAN [view interactions] High throughput no yes
GLUT4_HUMAN [view interactions] High throughput no no
LRRK2_HUMAN [view interactions] High throughput no yes
RAB6C_HUMAN [view interactions] High throughput no no
MICA3_HUMAN [view interactions] High throughput no yes
RAB19_HUMAN [view interactions] High throughput no no
RB39A_HUMAN [view interactions] High throughput no no
RAB35_HUMAN [view entry] [view interactions] High throughput yes yes
RAE2_HUMAN [view interactions] High throughput no yes
RAE1_HUMAN [view interactions] High throughput no yes
RAB12_HUMAN [view entry] [view interactions] High throughput yes no