PRRT2_HUMAN
Evidence for PS localization
Functions
As a component of the outer core of AMPAR complex, may be involved in synaptic transmission in the central nervous system. In hippocampal neurons, in presynaptic terminals, plays an important role in the final steps of neurotransmitter release, possibly by regulating Ca(2+)-sensing. In the cerebellum, may inhibit SNARE complex formation and downregulate short-term facilitation. [View more on UniProt]
Protein features
Binary interactions with known binding regions
Interacting region for partners were not defined.
Network
Isoforms
Disease-causing germline mutations
| Position | Amino acid | Mutation | Disease | Overlap with binding region |
|---|---|---|---|---|
| 266 | Arg | Trp | Episodickinesigenicdyskinesia1(EKD1) | - |
| 281 | Trp | Arg | Episodickinesigenicdyskinesia1(EKD1) | - |
| 287 | Ala | Thr | Episodickinesigenicdyskinesia1(EKD1) | - |
| 305 | Gly | Arg | Episodickinesigenicdyskinesia1(EKD1) | - |
| 308 | Arg | Cys | Episodickinesigenicdyskinesia1(EKD1) | - |
| 317 | Ser | Asn | Convulsions,familialinfantile,withparoxysmalchoreoathetosis(ICCA) | - |
| 323 | Gly | Glu | Seizures,benignfamilialinfantile,2(BFIS2) | - |
Linear motifs
No annotated instance was found. To search for linear motifs, use the ELM prediction server.
Fingerprint
Molecular function
| Term | Name | % | Distance from the top of the tree | Annotated in PRRT2_HUMAN |
|---|---|---|---|---|
| GO:0043169 | cation binding | 33.3333 | 4 | no |
| GO:0046872 | metal ion binding | 32.0261 | 5 | no |
| GO:0043168 | anion binding | 31.3725 | 4 | no |
| GO:0022890 | inorganic cation transmembrane transporter activity | 31.3725 | 4 | no |
| GO:0008324 | monoatomic cation transmembrane transporter activity | 30.7190 | 4 | no |
| GO:0000166 | nucleotide binding | 30.0654 | 4 | no |
| GO:0017076 | purine nucleotide binding | 27.4510 | 5 | no |
| GO:0032555 | purine ribonucleotide binding | 26.1438 | 4 | no |
| GO:0035639 | purine ribonucleoside triphosphate binding | 26.1438 | 4 | no |
| GO:0022853 | active monoatomic ion transmembrane transporter activity | 24.1830 | 4 | no |
| GO:0017111 | ribonucleoside triphosphate phosphatase activity | 23.5294 | 6 | no |
| GO:0016462 | pyrophosphatase activity | 23.5294 | 5 | no |
| GO:0016818 | hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides | 23.5294 | 4 | no |
| GO:0019905 | syntaxin binding | 4.5752 | 4 | yes |
| GO:0017075 | syntaxin-1 binding | 3.2680 | 5 | yes |
Biological process
| Term | Name | % | Distance from top the of the tree | Annotated in PRRT2_HUMAN |
|---|---|---|---|---|
| GO:0051049 | regulation of transport | 36.6013 | 4 | yes |
| GO:0048522 | positive regulation of cellular process | 35.2941 | 4 | no |
| GO:0010646 | regulation of cell communication | 35.2941 | 4 | yes |
| GO:0022607 | cellular component assembly | 28.7582 | 4 | no |
| GO:0048523 | negative regulation of cellular process | 28.7582 | 4 | yes |
| GO:0051128 | regulation of cellular component organization | 26.7974 | 4 | yes |
| GO:0071702 | organic substance transport | 25.4902 | 4 | no |
| GO:0008104 | protein localization | 24.8366 | 4 | no |
| GO:0071705 | nitrogen compound transport | 24.1830 | 4 | no |
| GO:0006996 | organelle organization | 24.1830 | 4 | yes |
| GO:0050804 | modulation of chemical synaptic transmission | 22.2222 | 5 | yes |
| GO:0099177 | regulation of trans-synaptic signaling | 22.2222 | 4 | yes |
| GO:0031323 | regulation of cellular metabolic process | 20.9150 | 4 | no |
| GO:0006811 | monoatomic ion transport | 20.9150 | 4 | no |
| GO:0006796 | phosphate-containing compound metabolic process | 20.2614 | 4 | no |
| GO:0009966 | regulation of signal transduction | 20.2614 | 4 | no |
| GO:0061024 | membrane organization | 18.3007 | 4 | yes |
| GO:0060627 | regulation of vesicle-mediated transport | 15.0327 | 4 | yes |
| GO:0033043 | regulation of organelle organization | 14.3791 | 5 | yes |
| GO:0044087 | regulation of cellular component biogenesis | 11.7647 | 4 | yes |
| GO:0051051 | negative regulation of transport | 8.4967 | 4 | yes |
| GO:0016050 | vesicle organization | 6.5359 | 5 | yes |
| GO:0051129 | negative regulation of cellular component organization | 6.5359 | 5 | yes |
| GO:0043254 | regulation of protein-containing complex assembly | 5.2288 | 5 | yes |
| GO:0048284 | organelle fusion | 5.2288 | 5 | yes |
| GO:0061025 | membrane fusion | 5.2288 | 5 | yes |
| GO:0006906 | vesicle fusion | 4.5752 | 6 | yes |
| GO:0090174 | organelle membrane fusion | 4.5752 | 6 | yes |
| GO:0048499 | synaptic vesicle membrane organization | 3.9216 | 5 | yes |
| GO:0050905 | neuromuscular process | 3.9216 | 4 | yes |
| GO:0031333 | negative regulation of protein-containing complex assembly | 2.6144 | 6 | yes |
| GO:0031338 | regulation of vesicle fusion | 2.6144 | 5 | yes |
| GO:0031629 | synaptic vesicle fusion to presynaptic active zone membrane | 2.6144 | 4 | yes |
| GO:0031630 | regulation of synaptic vesicle fusion to presynaptic active zone membrane | 2.6144 | 6 | yes |
| GO:1901632 | regulation of synaptic vesicle membrane organization | 2.6144 | 5 | yes |
| GO:0010639 | negative regulation of organelle organization | 1.3072 | 6 | yes |
Disease
No data found.
All partners
| Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
|---|---|---|---|---|
| GRIA1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| SNP25_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| VAMP2_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| STX1A_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| SNG3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| S25A3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| COX5A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GRM3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| TTYH1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CALM2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CALM3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CALM1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| STX6_HUMAN | [view interactions] | High throughput | no | yes |
| GBB4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KCNA1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RAB10_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| VDAC1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NDUA5_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RAB3C_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| QCR8_HUMAN | [view interactions] | High throughput | no | yes |
| GNAO_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TENR_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| QCR2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| STX1B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| VA0D1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RAC3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| NDUA9_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TBB4B_HUMAN | [view interactions] | High throughput | no | yes |
| AT1A1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| TBB3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AT1A2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NU4M_HUMAN | [view interactions] | High throughput | no | yes |
| PHB2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DPP6_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ITAV_HUMAN | [view interactions] | High throughput | no | yes |
| SV2A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NDUBA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| 4F2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CLH1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TERA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NDUV1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NDUA8_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GRIA2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PRRT3_HUMAN | [view interactions] | High throughput | no | yes |
| CACB1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PRAG1_HUMAN | [view interactions] | High throughput | no | yes |
| CACB4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ZNT3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HECAM_HUMAN | [view interactions] | High throughput | no | no |
| MAG_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| S2512_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AT8A1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NDUB5_HUMAN | [view interactions] | High throughput | no | yes |
| AT5L2_HUMAN | [view interactions] | High throughput | no | no |
| ATP5L_HUMAN | [view interactions] | High throughput | no | yes |
| GNAI2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CTNB1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TBB4A_HUMAN | [view interactions] | High throughput | no | yes |
| AP2A2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NTRK2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RAB5A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| STX12_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SYT2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| SYT3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| S6A17_HUMAN | [view interactions] | High throughput | no | yes |
| ABI1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ATLA1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| BRNP1_HUMAN | [view interactions] | High throughput | no | yes |
| DLG1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DYN2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GGT7_HUMAN | [view interactions] | High throughput | no | yes |
| GNA13_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GRM7_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| MFN2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SNAG_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NDUS5_HUMAN | [view interactions] | High throughput | no | yes |
| PRAF2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RAB18_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RAB8B_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| SCN2B_HUMAN | [view interactions] | High throughput | no | no |
| NSMA2_HUMAN | [view interactions] | High throughput | no | yes |
| SNG1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SYT12_HUMAN | [view interactions] | High throughput | no | yes |
| TMM33_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ATPMK_HUMAN | [view interactions] | High throughput | no | no |
| VAMP7_HUMAN | [view interactions] | High throughput | no | yes |
| WFS1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HSP7C_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SFXN3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NDUS2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NDUV2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TBA4A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| VDAC3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NDUBB_HUMAN | [view interactions] | High throughput | no | yes |
| PRRT1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NDUS7_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| AGK_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CNR1_HUMAN | [view interactions] | High throughput | no | yes |
| HMOX2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PLPP3_HUMAN | [view interactions] | High throughput | no | no |
| ZNT9_HUMAN | [view interactions] | High throughput | no | yes |
| KCNA3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| VDAC2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NDUB7_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ICAM5_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| YJEN3_HUMAN | [view interactions] | High throughput | no | yes |
| ACTB_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ACTG_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CXAR_HUMAN | [view interactions] | High throughput | no | yes |
| NDUA6_HUMAN | [view interactions] | High throughput | no | no |
| EAA2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RS27A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RL40_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| UBB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NDUAC_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CSPG5_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PTPRS_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| KCC2A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| UBC_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ATPO_HUMAN | [view interactions] | High throughput | no | yes |
| TCPH_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GUAD_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DPP10_HUMAN | [view interactions] | High throughput | no | yes |
| GNAI3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CACB2_HUMAN | [view interactions] | High throughput | no | yes |
| NDUB4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GNAZ_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PLXA1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RAB3A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ADA22_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ADA23_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ARM10_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| VATL_HUMAN | [view interactions] | High throughput | no | no |
| CCG8_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ENDD1_HUMAN | [view interactions] | High throughput | no | yes |
| GBRG2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CX6A1_HUMAN | [view interactions] | High throughput | no | yes |
| GBG2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NDUA1_HUMAN | [view interactions] | High throughput | no | yes |
| NRX3A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| OCAD1_HUMAN | [view interactions] | High throughput | no | yes |
| SEPT5_HUMAN | [view interactions] | High throughput | no | no |
| SCN1B_HUMAN | [view interactions] | High throughput | no | no |
| MYCT_HUMAN | [view interactions] | High throughput | no | yes |
| SC6A1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| TWF2_HUMAN | [view interactions] | High throughput | no | no |
| GNB5_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ATP5I_HUMAN | [view interactions] | High throughput | no | yes |
| CDC42_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ATP5H_HUMAN | [view interactions] | High throughput | no | yes |
| CN37_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RAB1B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TBA1B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TBA1A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AT2A2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CISD1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ARF1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ARF3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| SFXN5_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| SEPT8_HUMAN | [view interactions] | High throughput | no | no |
| S4A4_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| VGLU1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RAP2B_HUMAN | [view interactions] | High throughput | no | no |
| DYN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AT1A4_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| QCR1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SSR3_HUMAN | [view interactions] | High throughput | no | yes |
| SHSA7_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| SHAN3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| SMIM5_HUMAN | [view interactions] | High throughput | no | yes |
| SOAT_HUMAN | [view interactions] | High throughput | no | no |
| TLCD4_HUMAN | [view interactions] | High throughput | no | no |
| MF14B_HUMAN | [view interactions] | High throughput | no | no |
| GPC5D_HUMAN | [view interactions] | High throughput | no | yes |
| AQP6_HUMAN | [view interactions] | High throughput | no | no |
| PAR2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NDUV3_HUMAN | [view interactions] | High throughput | no | yes |
| CALL5_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| NDUB9_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NDUB8_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FAKD4_HUMAN | [view interactions] | High throughput | no | yes |
| NDUS4_HUMAN | [view interactions] | High throughput | no | yes |
| DDI1_HUMAN | [view interactions] | High throughput | no | no |
| LCLT1_HUMAN | [view interactions] | High throughput | no | no |
| IFM1_HUMAN | [view interactions] | High throughput | no | no |
| NDUB3_HUMAN | [view interactions] | High throughput | no | yes |
| F234A_HUMAN | [view interactions] | High throughput | no | yes |
| BRI3B_HUMAN | [view interactions] | High throughput | no | yes |
| GBB2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TPIS_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AT1B1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| FKBP8_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TMX2_HUMAN | [view interactions] | High throughput | no | yes |
| GBB1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AGRL1_HUMAN | [view interactions] | High throughput | no | no |
| S12A5_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NPTN_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ATPK_HUMAN | [view interactions] | High throughput | no | yes |
| BCS1_HUMAN | [view interactions] | High throughput | no | yes |
| KCAB2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CD81_HUMAN | [view interactions] | High throughput | no | no |
| CPLX2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| COX2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GRM2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NDUAA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AT2B2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| EAA1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| GTR14_HUMAN | [view interactions] | High throughput | no | no |
| GTR3_HUMAN | [view interactions] | High throughput | no | yes |
| AOFB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GNAI1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SYPH_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| VPP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SYT1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| GLO2_HUMAN | [view interactions] | High throughput | no | yes |
| LIPS_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| MPC1_HUMAN | [view interactions] | High throughput | no | yes |
| TBB5_HUMAN | [view interactions] | High throughput | no | yes |
| NCAM2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AT1A3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| REEP2_HUMAN | [view interactions] | High throughput | no | yes |
| CTL2_HUMAN | [view interactions] | High throughput | no | no |
| NDUS1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| KCNA2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |