STX1A_HUMAN
Evidence for PS localization
Functions
Plays an essential role in hormone and neurotransmitter calcium-dependent exocytosis and endocytosis (PubMed). Part of the SNARE (Soluble NSF Attachment Receptor) complex composed of SNAP25, STX1A and VAMP2 which mediates the fusion of synaptic vesicles with the presynaptic plasma membrane. STX1A and SNAP25 are localized on the plasma membrane while VAMP2 resides in synaptic vesicles. The pairing of the three SNAREs from the N-terminal SNARE motifs to the C-terminal anchors leads to the formation of the SNARE complex, which brings membranes into close proximity and results in final fusion. Participates in the calcium-dependent regulation of acrosomal exocytosis in sperm (PubMed). Plays also an important role in the exocytosis of hormones such as insulin or glucagon-like peptide 1 (GLP-1) . [View more on UniProt]
Protein features
Binary interactions with known binding regions
To display all evidence describing the interaction with a partner, click on the protein name left to the bars.
Network
Isoforms
Disease-causing germline mutations
No data found.
Linear motifs
No annotated instance was found. To search for linear motifs, use the ELM prediction server.
Fingerprint
Molecular function
| Term | Name | % | Distance from the top of the tree | Annotated in STX1A_HUMAN |
|---|---|---|---|---|
| GO:0046872 | metal ion binding | 31.7073 | 4 | no |
| GO:0019905 | syntaxin binding | 29.2683 | 4 | no |
| GO:0019900 | kinase binding | 14.6341 | 4 | yes |
| GO:0017022 | myosin binding | 4.8780 | 4 | yes |
| GO:0017081 | chloride channel regulator activity | 4.8780 | 4 | yes |
| GO:0019869 | chloride channel inhibitor activity | 4.8780 | 5 | yes |
| GO:0005246 | calcium channel regulator activity | 3.6585 | 4 | yes |
| GO:0008200 | ion channel inhibitor activity | 2.4390 | 4 | yes |
| GO:0019855 | calcium channel inhibitor activity | 2.4390 | 5 | yes |
| GO:0032028 | myosin head/neck binding | 2.4390 | 6 | yes |
| GO:0032036 | myosin heavy chain binding | 2.4390 | 5 | yes |
Biological process
| Term | Name | % | Distance from top the of the tree | Annotated in STX1A_HUMAN |
|---|---|---|---|---|
| GO:0016192 | vesicle-mediated transport | 54.8780 | 4 | yes |
| GO:0048522 | positive regulation of cellular process | 54.8780 | 4 | yes |
| GO:0051049 | regulation of transport | 52.4390 | 4 | yes |
| GO:0071702 | organic substance transport | 52.4390 | 4 | yes |
| GO:0008104 | protein localization | 50.0000 | 4 | yes |
| GO:0071705 | nitrogen compound transport | 50.0000 | 4 | yes |
| GO:0010646 | regulation of cell communication | 46.3415 | 4 | yes |
| GO:0015031 | protein transport | 42.6829 | 4 | yes |
| GO:0046903 | secretion | 42.6829 | 4 | yes |
| GO:0006996 | organelle organization | 41.4634 | 4 | yes |
| GO:0051128 | regulation of cellular component organization | 39.0244 | 4 | yes |
| GO:0051046 | regulation of secretion | 37.8049 | 5 | yes |
| GO:0006887 | exocytosis | 36.5854 | 4 | yes |
| GO:0050804 | modulation of chemical synaptic transmission | 36.5854 | 5 | yes |
| GO:0099177 | regulation of trans-synaptic signaling | 36.5854 | 4 | yes |
| GO:1903530 | regulation of secretion by cell | 36.5854 | 4 | yes |
| GO:0023061 | signal release | 34.1463 | 4 | yes |
| GO:0060627 | regulation of vesicle-mediated transport | 34.1463 | 4 | yes |
| GO:0051050 | positive regulation of transport | 32.9268 | 4 | yes |
| GO:0099643 | signal release from synapse | 32.9268 | 5 | yes |
| GO:0017157 | regulation of exocytosis | 31.7073 | 5 | yes |
| GO:0022607 | cellular component assembly | 31.7073 | 4 | yes |
| GO:0061024 | membrane organization | 31.7073 | 4 | yes |
| GO:0016050 | vesicle organization | 30.4878 | 5 | yes |
| GO:0043269 | regulation of ion transport | 30.4878 | 5 | yes |
| GO:0043933 | protein-containing complex organization | 28.0488 | 4 | yes |
| GO:0006886 | intracellular protein transport | 26.8293 | 4 | yes |
| GO:0048278 | vesicle docking | 26.8293 | 4 | yes |
| GO:0048523 | negative regulation of cellular process | 26.8293 | 4 | no |
| GO:0060255 | regulation of macromolecule metabolic process | 26.8293 | 4 | no |
| GO:0045055 | regulated exocytosis | 25.6098 | 5 | yes |
| GO:0061025 | membrane fusion | 25.6098 | 5 | yes |
| GO:0023056 | positive regulation of signaling | 24.3902 | 4 | yes |
| GO:0044087 | regulation of cellular component biogenesis | 24.3902 | 4 | yes |
| GO:0009893 | positive regulation of metabolic process | 24.3902 | 4 | no |
| GO:0006836 | neurotransmitter transport | 24.3902 | 4 | no |
| GO:0009966 | regulation of signal transduction | 23.1707 | 4 | yes |
| GO:0048284 | organelle fusion | 23.1707 | 5 | yes |
| GO:0060341 | regulation of cellular localization | 23.1707 | 4 | yes |
| GO:0065003 | protein-containing complex assembly | 23.1707 | 5 | yes |
| GO:0099003 | vesicle-mediated transport in synapse | 23.1707 | 5 | yes |
| GO:0010647 | positive regulation of cell communication | 21.9512 | 5 | yes |
| GO:0016079 | synaptic vesicle exocytosis | 21.9512 | 4 | yes |
| GO:0051047 | positive regulation of secretion | 21.9512 | 5 | yes |
| GO:1903305 | regulation of regulated secretory pathway | 21.9512 | 6 | yes |
| GO:0033043 | regulation of organelle organization | 21.9512 | 5 | no |
| GO:0006906 | vesicle fusion | 20.7317 | 6 | yes |
| GO:0032880 | regulation of protein localization | 20.7317 | 5 | yes |
| GO:0048584 | positive regulation of response to stimulus | 20.7317 | 4 | yes |
| GO:0072657 | protein localization to membrane | 20.7317 | 4 | yes |
| GO:0090174 | organelle membrane fusion | 20.7317 | 6 | yes |
| GO:0031323 | regulation of cellular metabolic process | 20.7317 | 4 | no |
| GO:0007268 | chemical synaptic transmission | 20.7317 | 6 | no |
| GO:0098916 | anterograde trans-synaptic signaling | 20.7317 | 5 | no |
| GO:0099537 | trans-synaptic signaling | 20.7317 | 4 | no |
| GO:0043270 | positive regulation of ion transport | 19.5122 | 5 | yes |
| GO:1903532 | positive regulation of secretion by cell | 19.5122 | 5 | yes |
| GO:0017156 | calcium-ion regulated exocytosis | 18.2927 | 6 | yes |
| GO:0045921 | positive regulation of exocytosis | 17.0732 | 6 | yes |
| GO:0046928 | regulation of neurotransmitter secretion | 17.0732 | 4 | yes |
| GO:0051588 | regulation of neurotransmitter transport | 17.0732 | 5 | yes |
| GO:0006897 | endocytosis | 14.6341 | 5 | yes |
| GO:0050806 | positive regulation of synaptic transmission | 14.6341 | 5 | yes |
| GO:0017158 | regulation of calcium ion-dependent exocytosis | 13.4146 | 7 | yes |
| GO:0043254 | regulation of protein-containing complex assembly | 13.4146 | 5 | yes |
| GO:0051952 | regulation of amine transport | 13.4146 | 5 | yes |
| GO:0070201 | regulation of establishment of protein localization | 13.4146 | 6 | yes |
| GO:0009967 | positive regulation of signal transduction | 12.1951 | 5 | yes |
| GO:0036211 | protein modification process | 12.1951 | 4 | yes |
| GO:0043412 | macromolecule modification | 12.1951 | 4 | yes |
| GO:0044057 | regulation of system process | 12.1951 | 4 | yes |
| GO:0048499 | synaptic vesicle membrane organization | 12.1951 | 5 | yes |
| GO:0051223 | regulation of protein transport | 12.1951 | 5 | yes |
| GO:1903307 | positive regulation of regulated secretory pathway | 12.1951 | 7 | yes |
| GO:0031629 | synaptic vesicle fusion to presynaptic active zone membrane | 10.9756 | 4 | yes |
| GO:0048488 | synaptic vesicle endocytosis | 10.9756 | 5 | yes |
| GO:0050433 | regulation of catecholamine secretion | 10.9756 | 5 | yes |
| GO:0140238 | presynaptic endocytosis | 10.9756 | 4 | yes |
| GO:0010807 | regulation of synaptic vesicle priming | 9.7561 | 6 | yes |
| GO:0016081 | synaptic vesicle docking | 8.5366 | 4 | yes |
| GO:0035493 | SNARE complex assembly | 8.5366 | 6 | yes |
| GO:0045956 | positive regulation of calcium ion-dependent exocytosis | 8.5366 | 8 | yes |
| GO:0046883 | regulation of hormone secretion | 8.5366 | 4 | yes |
| GO:0050708 | regulation of protein secretion | 8.5366 | 5 | yes |
| GO:0001956 | positive regulation of neurotransmitter secretion | 7.3171 | 5 | yes |
| GO:0002791 | regulation of peptide secretion | 7.3171 | 6 | yes |
| GO:0032446 | protein modification by small protein conjugation | 7.3171 | 6 | yes |
| GO:0050796 | regulation of insulin secretion | 7.3171 | 6 | yes |
| GO:0051590 | positive regulation of neurotransmitter transport | 7.3171 | 5 | yes |
| GO:0051954 | positive regulation of amine transport | 7.3171 | 5 | yes |
| GO:0070647 | protein modification by small protein conjugation or removal | 7.3171 | 5 | yes |
| GO:0090087 | regulation of peptide transport | 7.3171 | 5 | yes |
| GO:0090276 | regulation of peptide hormone secretion | 7.3171 | 5 | yes |
| GO:0009306 | protein secretion | 6.0976 | 4 | yes |
| GO:0009914 | hormone transport | 6.0976 | 4 | yes |
| GO:0031644 | regulation of nervous system process | 6.0976 | 5 | yes |
| GO:0035592 | establishment of protein localization to extracellular region | 6.0976 | 4 | yes |
| GO:0042886 | amide transport | 6.0976 | 5 | yes |
| GO:0046879 | hormone secretion | 6.0976 | 5 | yes |
| GO:0071692 | protein localization to extracellular region | 6.0976 | 5 | yes |
| GO:0098815 | modulation of excitatory postsynaptic potential | 6.0976 | 4 | yes |
| GO:2000463 | positive regulation of excitatory postsynaptic potential | 6.0976 | 5 | yes |
| GO:0002790 | peptide secretion | 4.8780 | 5 | yes |
| GO:0015833 | peptide transport | 4.8780 | 5 | yes |
| GO:0030072 | peptide hormone secretion | 4.8780 | 6 | yes |
| GO:0030073 | insulin secretion | 4.8780 | 5 | yes |
| GO:0033605 | positive regulation of catecholamine secretion | 4.8780 | 6 | yes |
| GO:0010701 | positive regulation of norepinephrine secretion | 3.6585 | 6 | yes |
| GO:0014061 | regulation of norepinephrine secretion | 3.6585 | 6 | yes |
| GO:0018193 | peptidyl-amino acid modification | 3.6585 | 5 | yes |
| GO:0016925 | protein sumoylation | 2.4390 | 7 | yes |
| GO:0018205 | peptidyl-lysine modification | 2.4390 | 6 | yes |
Disease
| Term | Name | % | Distance from top the of the tree | Annotated in STX1A_HUMAN |
|---|---|---|---|---|
| DOID:331 | central nervous system disease | 8.5366 | 3 | no |
| DOID:936 | brain disease | 6.0976 | 4 | no |
| DOID:1826 | epilepsy | 4.8780 | 5 | no |
| DOID:0050701 | electroclinical syndrome | 3.6585 | 6 | no |
| DOID:0112202 | developmental and epileptic encephalopathy | 2.4390 | 7 | no |
| DOID:1289 | neurodegenerative disease | 2.4390 | 4 | no |
All partners
| Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
|---|---|---|---|---|
| UN13A_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| CMGA_HUMAN | [view interactions] | Low throughput | no | yes |
| CAPS1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| STXB3_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| SNAA_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| UN13B_HUMAN | [view interactions] | Low throughput | no | no |
| STXB2_HUMAN | [view interactions] | Low throughput | no | no |
| SCNNA_HUMAN | [view interactions] | Low throughput | no | yes |
| SCNNG_HUMAN | [view interactions] | Low throughput | no | no |
| SCNNB_HUMAN | [view interactions] | Low throughput | no | yes |
| SYTL4_HUMAN | [view interactions] | Low throughput | no | yes |
| BRE1B_HUMAN | [view interactions] | Low throughput | no | yes |
| CPLX2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| CFTR_HUMAN | [view interactions] | Low throughput | no | no |
| SYPH_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| SC6A4_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| SC6A1_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| SC6A9_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| SC6A5_HUMAN | [view interactions] | Low throughput | no | no |
| SC6A2_HUMAN | [view interactions] | Low throughput | no | no |
| SC6A3_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| HGS_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| CAC1D_HUMAN | [view interactions] | Low throughput | no | yes |
| KCNB1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| SNPH_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| VAPA_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| STXB5_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| CDK5_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| PRRT2_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| AT2B2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| VAMP2_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| VAMP1_HUMAN | [view interactions] | Low throughput | no | no |
| SNP23_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| SNP29_HUMAN | [view interactions] | Low throughput | no | yes |
| SC22B_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| STXB1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| SNP47_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| SEPT5_HUMAN | [view interactions] | Low throughput | no | no |
| SNP25_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| APBA1_HUMAN | [view interactions] | Low throughput | no | no |
| VAMP8_HUMAN | [view interactions] | Low throughput | no | no |
| SYUA_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| LRRK2_HUMAN | [view interactions] | Low throughput | no | yes |
| RUSC1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| HD_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| CPLX1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| VAMP7_HUMAN | [view interactions] | Low throughput | no | yes |
| SYT2_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| RP3A_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| APBA2_HUMAN | [view interactions] | Low throughput | no | yes |
| SYT1_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| KCMA1_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| NSF_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| SYT7_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| STX1A_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| TXLNA_HUMAN | [view interactions] | Low throughput | no | yes |
| TXLNB_HUMAN | [view interactions] | Low throughput | no | no |
| VAMP3_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| CLC1A_HUMAN | [view interactions] | High throughput | no | no |
| SNORC_HUMAN | [view interactions] | High throughput | no | yes |
| ZN785_HUMAN | [view interactions] | High throughput | no | no |
| STX5_HUMAN | [view interactions] | High throughput | no | yes |
| AOC3_HUMAN | [view interactions] | High throughput | no | no |
| T3JAM_HUMAN | [view interactions] | High throughput | no | no |
| SEC20_HUMAN | [view interactions] | High throughput | no | yes |
| TM199_HUMAN | [view interactions] | High throughput | no | yes |
| TM100_HUMAN | [view interactions] | High throughput | no | yes |
| AQP3_HUMAN | [view interactions] | High throughput | no | no |
| BL1S6_HUMAN | [view interactions] | High throughput | no | yes |
| MALL_HUMAN | [view interactions] | High throughput | no | no |
| ZN707_HUMAN | [view interactions] | High throughput | no | yes |
| MIP_HUMAN | [view interactions] | High throughput | no | no |
| ZN490_HUMAN | [view interactions] | High throughput | no | no |
| BT2A2_HUMAN | [view interactions] | High throughput | no | no |
| CDC37_HUMAN | [view interactions] | High throughput | no | yes |
| AARD_HUMAN | [view interactions] | High throughput | no | no |
| SERP1_HUMAN | [view interactions] | High throughput | no | no |
| T10IP_HUMAN | [view interactions] | High throughput | no | no |
| RMD2_HUMAN | [view interactions] | High throughput | no | yes |
| ZN696_HUMAN | [view interactions] | High throughput | no | no |
| HMOX1_HUMAN | [view interactions] | High throughput | no | no |
| EMD_HUMAN | [view interactions] | High throughput | no | yes |
| VTI1B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ZNF12_HUMAN | [view interactions] | High throughput | no | no |
| TMM60_HUMAN | [view interactions] | High throughput | no | no |
| PPLA_HUMAN | [view interactions] | High throughput | no | no |
| GIMA1_HUMAN | [view interactions] | High throughput | no | yes |
| TACAN_HUMAN | [view interactions] | High throughput | no | no |
| GOSR2_HUMAN | [view interactions] | High throughput | no | yes |
| EMC5_HUMAN | [view interactions] | High throughput | no | yes |
| RCAS1_HUMAN | [view interactions] | High throughput | no | yes |
| AR13B_HUMAN | [view interactions] | High throughput | no | yes |
| RNF4_HUMAN | [view interactions] | High throughput | no | yes |
| ZN136_HUMAN | [view interactions] | High throughput | no | no |
| CLN6_HUMAN | [view interactions] | High throughput | no | no |
| TRDMT_HUMAN | [view interactions] | High throughput | no | yes |
| VIME_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CCSE2_HUMAN | [view interactions] | High throughput | no | yes |
| DISC1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CLH1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MDM2_HUMAN | [view interactions] | High throughput | no | yes |
| GPM6B_HUMAN | [view interactions] | High throughput | no | yes |
| UBC9_HUMAN | [view interactions] | High throughput | no | yes |
| STX10_HUMAN | [view interactions] | High throughput | no | yes |
| C1GLT_HUMAN | [view interactions] | High throughput | no | yes |
| STX2_HUMAN | [view interactions] | High throughput | no | no |
| MYPR_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| STX16_HUMAN | [view interactions] | High throughput | no | yes |
| APOL3_HUMAN | [view interactions] | High throughput | no | no |
| ZN557_HUMAN | [view interactions] | High throughput | no | no |
| TM128_HUMAN | [view interactions] | High throughput | no | yes |
| KIFC3_HUMAN | [view interactions] | High throughput | no | no |
| AIG1_HUMAN | [view interactions] | High throughput | no | no |
| PGAP2_HUMAN | [view interactions] | High throughput | no | yes |
| CXL16_HUMAN | [view interactions] | High throughput | no | no |
| CD003_HUMAN | [view interactions] | High throughput | no | yes |
| GOLM2_HUMAN | [view interactions] | High throughput | no | yes |
| TSNA1_HUMAN | [view interactions] | High throughput | no | yes |
| TEANC_HUMAN | [view interactions] | High throughput | no | no |
| ATRAP_HUMAN | [view interactions] | High throughput | no | yes |
| ANR46_HUMAN | [view interactions] | High throughput | no | yes |
| ZN250_HUMAN | [view interactions] | High throughput | no | yes |
| PP1A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PP1G_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| UBC_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| VPS11_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| VPS18_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| VAPB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MS18B_HUMAN | [view interactions] | High throughput | no | no |
| HAX1_HUMAN | [view interactions] | High throughput | no | no |
| NUFP1_HUMAN | [view interactions] | High throughput | no | yes |
| DGUOK_HUMAN | [view interactions] | High throughput | no | yes |
| KTU_HUMAN | [view interactions] | High throughput | no | yes |
| CDR2_HUMAN | [view interactions] | High throughput | no | yes |
| STXB6_HUMAN | [view interactions] | High throughput | no | yes |
| TNIP2_HUMAN | [view interactions] | High throughput | no | yes |
| APEX1_HUMAN | [view interactions] | High throughput | no | yes |
| TAU_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CHM4C_HUMAN | [view interactions] | High throughput | no | yes |
| GPM6A_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| FAM9C_HUMAN | [view interactions] | High throughput | no | no |
| VATB1_HUMAN | [view interactions] | High throughput | no | no |
| VPS16_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CPLX3_HUMAN | [view interactions] | High throughput | no | no |
| SNX4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| STX1B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SHAN3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| DPP8_HUMAN | [view interactions] | High throughput | no | yes |
| ITM2B_HUMAN | [view interactions] | High throughput | no | yes |
| PSA3_HUMAN | [view interactions] | High throughput | no | no |
| SNAB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SUMO5_HUMAN | [view interactions] | High throughput | no | no |
| MAL_HUMAN | [view interactions] | High throughput | no | no |
| SMIM1_HUMAN | [view interactions] | High throughput | no | yes |
| UPK1B_HUMAN | [view interactions] | High throughput | no | no |
| SMIM3_HUMAN | [view interactions] | High throughput | no | no |
| R3GEF_HUMAN | [view interactions] | High throughput | no | yes |
| SC22A_HUMAN | [view interactions] | High throughput | no | no |
| CYB5B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SERP2_HUMAN | [view interactions] | High throughput | no | no |
| PLPP6_HUMAN | [view interactions] | High throughput | no | yes |
| LIPR1_HUMAN | [view interactions] | High throughput | no | no |
| NKG7_HUMAN | [view interactions] | High throughput | no | no |
| TNFA_HUMAN | [view interactions] | High throughput | no | no |
| VAMP5_HUMAN | [view interactions] | High throughput | no | no |
| RTP2_HUMAN | [view interactions] | High throughput | no | no |
| VAMP4_HUMAN | [view interactions] | High throughput | no | yes |
| STX11_HUMAN | [view interactions] | High throughput | no | yes |
| ZFPL1_HUMAN | [view interactions] | High throughput | no | yes |
| FAM3C_HUMAN | [view interactions] | High throughput | no | yes |
| STX7_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NINJ2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| DWORF_HUMAN | [view interactions] | High throughput | no | no |
| APOL2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DDX49_HUMAN | [view interactions] | High throughput | no | no |
| ZN835_HUMAN | [view interactions] | High throughput | no | no |
| ZN479_HUMAN | [view interactions] | High throughput | no | no |
| BET1_HUMAN | [view interactions] | High throughput | no | no |
| CKLF7_HUMAN | [view interactions] | High throughput | no | no |
| GIMA5_HUMAN | [view interactions] | High throughput | no | no |
| STX4_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| TM222_HUMAN | [view interactions] | High throughput | no | no |
| ZN441_HUMAN | [view interactions] | High throughput | no | no |
| CD81_HUMAN | [view interactions] | High throughput | no | no |
| JAGN1_HUMAN | [view interactions] | High throughput | no | no |
| STX8_HUMAN | [view interactions] | High throughput | no | yes |
| TM14C_HUMAN | [view interactions] | High throughput | no | no |
| STX12_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NRM_HUMAN | [view interactions] | High throughput | no | no |
| VSTM4_HUMAN | [view interactions] | High throughput | no | yes |
| EKI2_HUMAN | [view interactions] | High throughput | no | yes |
| ERG28_HUMAN | [view interactions] | High throughput | no | yes |
| ABI3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ZN440_HUMAN | [view interactions] | High throughput | no | no |
| USE1_HUMAN | [view interactions] | High throughput | no | yes |
| UBFL1_HUMAN | [view interactions] | High throughput | no | no |
| STX6_HUMAN | [view interactions] | High throughput | no | yes |
| PLPP4_HUMAN | [view interactions] | High throughput | no | yes |
| TM41A_HUMAN | [view interactions] | High throughput | no | no |
| STX3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| TM254_HUMAN | [view interactions] | High throughput | no | yes |
| GNAI2_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| CACB2_HUMAN | [view interactions] | Computational | no | yes |
| OTOF_HUMAN | [view interactions] | Computational | no | yes |
| STB5L_HUMAN | [view interactions] | Computational | no | no |
| RIMS1_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| SYT5_HUMAN | [view entry] [view interactions] | Computational | yes | no |
| GNAI1_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| UB2J2_HUMAN | [view interactions] | Computational | no | no |
| SC61B_HUMAN | [view interactions] | Computational | no | yes |
| SCG1_HUMAN | [view interactions] | Computational | no | no |
| CAC1C_HUMAN | [view entry] [view interactions] | Computational | yes | no |
| YKT6_HUMAN | [view interactions] | Computational | no | yes |
| DPYL2_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| SYN1_HUMAN | [view entry] [view interactions] | Computational | yes | no |
| AL3A2_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| ABCC8_HUMAN | [view interactions] | Computational | no | yes |
| LIPA3_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| LIN7C_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| SYN2_HUMAN | [view entry] [view interactions] | Computational | yes | no |
| LIN7A_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| KCNA1_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| CAC1B_HUMAN | [view interactions] | Computational | no | yes |
| CPLX4_HUMAN | [view interactions] | Computational | no | no |
| STX17_HUMAN | [view interactions] | Computational | no | yes |
| DNJC5_HUMAN | [view interactions] | Computational | no | yes |
| RAB3A_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| SIA8B_HUMAN | [view interactions] | Computational | no | yes |
| CYB5_HUMAN | [view interactions] | Computational | no | no |
| CA2D2_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| MYO5A_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| LIN7B_HUMAN | [view entry] [view interactions] | Computational | yes | no |
| KCNB2_HUMAN | [view interactions] | Computational | no | no |
| INS_HUMAN | [view interactions] | Computational | no | no |
| RBGPR_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| SC61G_HUMAN | [view interactions] | Computational | no | yes |
| CACB3_HUMAN | [view entry] [view interactions] | Computational | yes | no |