SC6A4_HUMAN
Evidence for PS localization
Functions
Serotonin transporter whose primary function in the central nervous system involves the regulation of serotonergic signaling via transport of serotonin molecules from the synaptic cleft back into the pre-synaptic terminal for re-utilization. Plays a key role in mediating regulation of the availability of serotonin to other receptors of serotonergic systems. Terminates the action of serotonin and recycles it in a sodium-dependent manner. [View more on UniProt]
Protein features
Binary interactions with known binding regions
To display all evidence describing the interaction with a partner, click on the protein name left to the bars.
Network
Isoforms
Disease-causing germline mutations
No data found.
Linear motifs
No annotated instance was found. To search for linear motifs, use the ELM prediction server.
Fingerprint
Molecular function
| Term | Name | % | Distance from the top of the tree | Annotated in SC6A4_HUMAN |
|---|---|---|---|---|
| GO:0043168 | anion binding | 27.9570 | 4 | no |
| GO:0000166 | nucleotide binding | 25.0896 | 4 | no |
| GO:0017076 | purine nucleotide binding | 24.7312 | 5 | no |
| GO:0043169 | cation binding | 22.9391 | 4 | yes |
| GO:0032555 | purine ribonucleotide binding | 22.9391 | 4 | no |
| GO:0046872 | metal ion binding | 22.2222 | 5 | yes |
| GO:0035639 | purine ribonucleoside triphosphate binding | 22.2222 | 4 | no |
| GO:0030554 | adenyl nucleotide binding | 20.7885 | 6 | no |
| GO:0003779 | actin binding | 13.2616 | 4 | yes |
| GO:0022890 | inorganic cation transmembrane transporter activity | 6.8100 | 4 | yes |
| GO:0008324 | monoatomic cation transmembrane transporter activity | 5.3763 | 4 | yes |
| GO:0005216 | monoatomic ion channel activity | 4.6595 | 4 | yes |
| GO:0015267 | channel activity | 4.6595 | 4 | yes |
| GO:0022853 | active monoatomic ion transmembrane transporter activity | 3.2258 | 4 | yes |
| GO:0046873 | metal ion transmembrane transporter activity | 3.2258 | 5 | yes |
| GO:0005261 | monoatomic cation channel activity | 2.5090 | 5 | yes |
| GO:0019905 | syntaxin binding | 2.1505 | 4 | yes |
| GO:0015291 | secondary active transmembrane transporter activity | 1.7921 | 4 | yes |
| GO:0017075 | syntaxin-1 binding | 1.4337 | 5 | yes |
| GO:0008509 | monoatomic anion transmembrane transporter activity | 1.4337 | 4 | yes |
| GO:0015081 | sodium ion transmembrane transporter activity | 1.4337 | 6 | yes |
| GO:0015103 | inorganic anion transmembrane transporter activity | 1.4337 | 4 | yes |
| GO:0015297 | antiporter activity | 1.4337 | 5 | yes |
| GO:0031420 | alkali metal ion binding | 1.0753 | 6 | yes |
| GO:0015108 | chloride transmembrane transporter activity | 1.0753 | 5 | yes |
| GO:0015293 | symporter activity | 1.0753 | 5 | yes |
| GO:0015294 | solute:monoatomic cation symporter activity | 1.0753 | 5 | yes |
| GO:0015370 | solute:sodium symporter activity | 1.0753 | 6 | yes |
| GO:0015378 | sodium:chloride symporter activity | 0.7168 | 7 | yes |
| GO:0031402 | sodium ion binding | 0.7168 | 7 | yes |
| GO:0050998 | nitric-oxide synthase binding | 0.7168 | 4 | yes |
| GO:0005335 | serotonin:sodium:chloride symporter activity | 0.7168 | 4 | yes |
| GO:0008504 | monoamine transmembrane transporter activity | 0.7168 | 4 | yes |
| GO:0015296 | monoatomic anion:monoatomic cation symporter activity | 0.7168 | 5 | yes |
| GO:0015373 | monoatomic anion:sodium symporter activity | 0.7168 | 6 | yes |
| GO:0015377 | chloride:monoatomic cation symporter activity | 0.7168 | 6 | yes |
Biological process
| Term | Name | % | Distance from top the of the tree | Annotated in SC6A4_HUMAN |
|---|---|---|---|---|
| GO:0048522 | positive regulation of cellular process | 50.5376 | 4 | yes |
| GO:0010646 | regulation of cell communication | 42.6523 | 4 | yes |
| GO:0051128 | regulation of cellular component organization | 39.0681 | 4 | no |
| GO:0048523 | negative regulation of cellular process | 37.6344 | 4 | yes |
| GO:0031323 | regulation of cellular metabolic process | 36.2007 | 4 | yes |
| GO:0060255 | regulation of macromolecule metabolic process | 35.8423 | 4 | yes |
| GO:0006996 | organelle organization | 34.4086 | 4 | no |
| GO:0009966 | regulation of signal transduction | 32.2581 | 4 | no |
| GO:0080090 | regulation of primary metabolic process | 32.2581 | 4 | no |
| GO:0022607 | cellular component assembly | 30.4659 | 4 | no |
| GO:0008104 | protein localization | 28.3154 | 4 | no |
| GO:0009893 | positive regulation of metabolic process | 28.3154 | 4 | yes |
| GO:0009889 | regulation of biosynthetic process | 27.2401 | 4 | yes |
| GO:0051049 | regulation of transport | 27.2401 | 4 | yes |
| GO:0010604 | positive regulation of macromolecule metabolic process | 26.8817 | 5 | yes |
| GO:0031326 | regulation of cellular biosynthetic process | 26.5233 | 5 | yes |
| GO:0010556 | regulation of macromolecule biosynthetic process | 25.8065 | 5 | yes |
| GO:0010468 | regulation of gene expression | 24.3728 | 6 | yes |
| GO:0031325 | positive regulation of cellular metabolic process | 23.2975 | 5 | yes |
| GO:0051246 | regulation of protein metabolic process | 22.5806 | 5 | no |
| GO:0023056 | positive regulation of signaling | 21.5054 | 4 | no |
| GO:0051130 | positive regulation of cellular component organization | 21.5054 | 5 | no |
| GO:0010647 | positive regulation of cell communication | 21.1470 | 5 | no |
| GO:0048584 | positive regulation of response to stimulus | 21.1470 | 4 | no |
| GO:0071702 | organic substance transport | 17.9211 | 4 | yes |
| GO:0099177 | regulation of trans-synaptic signaling | 17.2043 | 4 | yes |
| GO:0050804 | modulation of chemical synaptic transmission | 17.2043 | 5 | yes |
| GO:0009891 | positive regulation of biosynthetic process | 16.8459 | 5 | yes |
| GO:0031328 | positive regulation of cellular biosynthetic process | 16.8459 | 6 | yes |
| GO:0071705 | nitrogen compound transport | 16.4875 | 4 | yes |
| GO:0010557 | positive regulation of macromolecule biosynthetic process | 16.1290 | 6 | yes |
| GO:0051050 | positive regulation of transport | 15.7706 | 4 | yes |
| GO:0071310 | cellular response to organic substance | 15.7706 | 4 | yes |
| GO:0010648 | negative regulation of cell communication | 15.0538 | 5 | yes |
| GO:0023057 | negative regulation of signaling | 15.0538 | 4 | yes |
| GO:0042127 | regulation of cell population proliferation | 13.2616 | 4 | yes |
| GO:0045595 | regulation of cell differentiation | 12.5448 | 4 | yes |
| GO:0098657 | import into cell | 12.1864 | 4 | yes |
| GO:0051046 | regulation of secretion | 11.1111 | 5 | yes |
| GO:0033993 | response to lipid | 10.7527 | 4 | yes |
| GO:1903530 | regulation of secretion by cell | 10.3943 | 4 | yes |
| GO:0051241 | negative regulation of multicellular organismal process | 10.0358 | 4 | yes |
| GO:1901701 | cellular response to oxygen-containing compound | 9.6774 | 4 | yes |
| GO:0010628 | positive regulation of gene expression | 9.6774 | 7 | yes |
| GO:0043269 | regulation of monoatomic ion transport | 9.3190 | 5 | yes |
| GO:0014070 | response to organic cyclic compound | 8.9606 | 4 | yes |
| GO:0010243 | response to organonitrogen compound | 8.2437 | 4 | yes |
| GO:0051726 | regulation of cell cycle | 8.2437 | 4 | yes |
| GO:0008285 | negative regulation of cell population proliferation | 7.1685 | 5 | yes |
| GO:0043270 | positive regulation of monoatomic ion transport | 6.8100 | 5 | yes |
| GO:0071396 | cellular response to lipid | 6.4516 | 5 | yes |
| GO:1901699 | cellular response to nitrogen compound | 5.7348 | 4 | yes |
| GO:0006811 | monoatomic ion transport | 5.7348 | 4 | yes |
| GO:0050890 | cognition | 5.7348 | 4 | yes |
| GO:0006812 | monoatomic cation transport | 5.3763 | 5 | yes |
| GO:0051047 | positive regulation of secretion | 5.3763 | 5 | yes |
| GO:0051093 | negative regulation of developmental process | 5.3763 | 4 | yes |
| GO:0071407 | cellular response to organic cyclic compound | 5.3763 | 5 | yes |
| GO:0071417 | cellular response to organonitrogen compound | 5.3763 | 4 | yes |
| GO:0030001 | metal ion transport | 5.0179 | 6 | yes |
| GO:0045596 | negative regulation of cell differentiation | 5.0179 | 5 | yes |
| GO:1903532 | positive regulation of secretion by cell | 4.6595 | 5 | yes |
| GO:0098655 | monoatomic cation transmembrane transport | 3.9427 | 4 | yes |
| GO:0098662 | inorganic cation transmembrane transport | 3.9427 | 4 | yes |
| GO:0003018 | vascular process in circulatory system | 3.2258 | 4 | yes |
| GO:0036293 | response to decreased oxygen levels | 3.2258 | 4 | yes |
| GO:0048638 | regulation of developmental growth | 3.2258 | 4 | yes |
| GO:2000177 | regulation of neural precursor cell proliferation | 2.8674 | 5 | yes |
| GO:0032355 | response to estradiol | 2.8674 | 4 | yes |
| GO:0045664 | regulation of neuron differentiation | 2.8674 | 5 | yes |
| GO:0045787 | positive regulation of cell cycle | 2.8674 | 5 | yes |
| GO:0045926 | negative regulation of growth | 2.8674 | 4 | yes |
| GO:0006836 | neurotransmitter transport | 2.5090 | 4 | yes |
| GO:0007613 | memory | 2.5090 | 4 | yes |
| GO:0032526 | response to retinoic acid | 2.5090 | 4 | yes |
| GO:0050805 | negative regulation of synaptic transmission | 2.1505 | 5 | yes |
| GO:0071300 | cellular response to retinoic acid | 2.1505 | 5 | yes |
| GO:0006814 | sodium ion transport | 1.7921 | 7 | yes |
| GO:0015850 | organic hydroxy compound transport | 1.7921 | 5 | yes |
| GO:0034109 | homotypic cell-cell adhesion | 1.7921 | 4 | yes |
| GO:0035150 | regulation of tube size | 1.7921 | 4 | yes |
| GO:0035296 | regulation of tube diameter | 1.7921 | 5 | yes |
| GO:0045665 | negative regulation of neuron differentiation | 1.7921 | 6 | yes |
| GO:0097746 | blood vessel diameter maintenance | 1.7921 | 5 | yes |
| GO:2000178 | negative regulation of neural precursor cell proliferation | 1.4337 | 6 | yes |
| GO:0001504 | neurotransmitter uptake | 1.4337 | 5 | yes |
| GO:0014074 | response to purine-containing compound | 1.4337 | 5 | yes |
| GO:0015844 | monoamine transport | 1.4337 | 5 | yes |
| GO:0035725 | sodium ion transmembrane transport | 1.4337 | 5 | yes |
| GO:0046683 | response to organophosphorus | 1.4337 | 4 | yes |
| GO:0048640 | negative regulation of developmental growth | 1.4337 | 5 | yes |
| GO:0048854 | brain morphogenesis | 1.4337 | 4 | yes |
| GO:0070305 | response to cGMP | 1.4337 | 4 | yes |
| GO:0070527 | platelet aggregation | 1.4337 | 5 | yes |
| GO:0071321 | cellular response to cGMP | 1.4337 | 5 | yes |
| GO:0032225 | regulation of synaptic transmission, dopaminergic | 1.0753 | 6 | yes |
| GO:0051899 | membrane depolarization | 1.0753 | 4 | yes |
| GO:0098810 | neurotransmitter reuptake | 1.0753 | 4 | yes |
| GO:0006837 | serotonin transport | 0.7168 | 6 | yes |
| GO:0014062 | regulation of serotonin secretion | 0.7168 | 5 | yes |
| GO:0014064 | positive regulation of serotonin secretion | 0.7168 | 6 | yes |
| GO:0021936 | regulation of cerebellar granule cell precursor proliferation | 0.7168 | 6 | yes |
| GO:0021941 | negative regulation of cerebellar granule cell precursor proliferation | 0.7168 | 7 | yes |
| GO:0032227 | negative regulation of synaptic transmission, dopaminergic | 0.7168 | 6 | yes |
| GO:0042310 | vasoconstriction | 0.7168 | 6 | yes |
| GO:0046620 | regulation of organ growth | 0.7168 | 4 | yes |
| GO:0046621 | negative regulation of organ growth | 0.7168 | 5 | yes |
| GO:0048484 | enteric nervous system development | 0.7168 | 4 | yes |
| GO:0051610 | serotonin uptake | 0.7168 | 5 | yes |
| GO:0090067 | regulation of thalamus size | 0.7168 | 4 | yes |
Disease
No data found.
All partners
| Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
|---|---|---|---|---|
| GPM6B_HUMAN | [view interactions] | Low throughput | no | yes |
| NOS1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| PICK1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| SCAM2_HUMAN | [view interactions] | Low throughput | no | no |
| STX1A_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| MAGD1_HUMAN | [view interactions] | Low throughput | no | no |
| SYUA_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| SYUG_HUMAN | [view interactions] | Low throughput | no | yes |
| HS71B_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| HS71A_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| HSP7C_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| HS90B_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| STIP1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| CHIP_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| TEBP_HUMAN | [view interactions] | Low throughput | no | yes |
| VAMP2_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| PP2BA_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| CALM2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| CALM3_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| CALM1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| ITA3_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| DGKD_HUMAN | [view interactions] | Low throughput | no | yes |
| SYVN1_HUMAN | [view interactions] | Low throughput | no | yes |
| CALX_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| CALR_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| A2MG_HUMAN | [view interactions] | Low throughput | no | yes |
| NGF_HUMAN | [view interactions] | Low throughput | no | no |
| PGCA_HUMAN | [view interactions] | High throughput | no | no |
| MAST1_HUMAN | [view interactions] | High throughput | no | yes |
| SNUT1_HUMAN | [view interactions] | High throughput | no | yes |
| VAPA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DNM1L_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PTN13_HUMAN | [view interactions] | High throughput | no | yes |
| GLPK_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| DP13B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PRIC2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| GCP2_HUMAN | [view interactions] | High throughput | no | yes |
| NFASC_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AP180_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DGLA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CSK21_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TOLIP_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TBAL3_HUMAN | [view interactions] | High throughput | no | no |
| LZTS3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DC2I2_HUMAN | [view interactions] | High throughput | no | yes |
| CLIP3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| JIP2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ARAF_HUMAN | [view interactions] | High throughput | no | yes |
| DECR2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| AGO2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NDUV1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TMOD1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HCN2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| MA7D2_HUMAN | [view interactions] | High throughput | no | yes |
| SCP2_HUMAN | [view interactions] | High throughput | no | no |
| GLT16_HUMAN | [view interactions] | High throughput | no | yes |
| UBP12_HUMAN | [view interactions] | High throughput | no | yes |
| NDUA9_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| K1549_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MAGI3_HUMAN | [view interactions] | High throughput | no | no |
| ELP3_HUMAN | [view interactions] | High throughput | no | no |
| GCP3_HUMAN | [view interactions] | High throughput | no | yes |
| ARMX1_HUMAN | [view interactions] | High throughput | no | yes |
| DC1L1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CAMP2_HUMAN | [view interactions] | High throughput | no | yes |
| UBR5_HUMAN | [view interactions] | High throughput | no | no |
| PDK3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TB10B_HUMAN | [view interactions] | High throughput | no | no |
| FKBP8_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NWD2_HUMAN | [view interactions] | High throughput | no | no |
| SRP68_HUMAN | [view interactions] | High throughput | no | yes |
| ARP5L_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| E41L1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CAMP3_HUMAN | [view interactions] | High throughput | no | no |
| SRAC1_HUMAN | [view interactions] | High throughput | no | yes |
| ARHG7_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MICU3_HUMAN | [view interactions] | High throughput | no | yes |
| AMOT_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| MAGI1_HUMAN | [view interactions] | High throughput | no | no |
| AGRL1_HUMAN | [view interactions] | High throughput | no | no |
| TFB1M_HUMAN | [view interactions] | High throughput | no | yes |
| OSBL6_HUMAN | [view interactions] | High throughput | no | yes |
| FLII_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RFXK_HUMAN | [view interactions] | High throughput | no | yes |
| TCPA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| INADL_HUMAN | [view interactions] | High throughput | no | no |
| PLPL8_HUMAN | [view interactions] | High throughput | no | yes |
| SC23A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NLGN3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CDKL5_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ELFN1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CSKI1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PAHX_HUMAN | [view interactions] | High throughput | no | yes |
| MTSS2_HUMAN | [view interactions] | High throughput | no | yes |
| PTPR2_HUMAN | [view interactions] | High throughput | no | yes |
| PRDX2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CBR4_HUMAN | [view interactions] | High throughput | no | yes |
| PROF2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NDUS2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| S2546_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DAB2P_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ACTN4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SI1L2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DUS2_HUMAN | [view interactions] | High throughput | no | no |
| PHKG1_HUMAN | [view interactions] | High throughput | no | no |
| DLGP2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| MCCA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HAP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| BIN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ARGL1_HUMAN | [view interactions] | High throughput | no | yes |
| VINC_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ADA22_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| LACTB_HUMAN | [view interactions] | High throughput | no | yes |
| LUZP1_HUMAN | [view interactions] | High throughput | no | yes |
| TPPC5_HUMAN | [view interactions] | High throughput | no | yes |
| RDH13_HUMAN | [view interactions] | High throughput | no | no |
| ML12B_HUMAN | [view interactions] | High throughput | no | no |
| DLG1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GNAZ_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DZAN1_HUMAN | [view interactions] | High throughput | no | yes |
| REPS2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CAZA1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ROGDI_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RENT1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SGPL1_HUMAN | [view interactions] | High throughput | no | yes |
| MARK2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CC177_HUMAN | [view interactions] | High throughput | no | no |
| SEP11_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CDC42_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| VIAAT_HUMAN | [view interactions] | High throughput | no | yes |
| GRIP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SEPT8_HUMAN | [view interactions] | High throughput | no | no |
| MP2K1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FXR1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GPX4_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| MPC1_HUMAN | [view interactions] | High throughput | no | yes |
| DIRA2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| TECR_HUMAN | [view interactions] | High throughput | no | yes |
| PP2AB_HUMAN | [view interactions] | High throughput | no | yes |
| AGAP1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| DGKB_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| FINC_HUMAN | [view interactions] | High throughput | no | yes |
| 1433B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| COR1C_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TM160_HUMAN | [view interactions] | High throughput | no | no |
| SQOR_HUMAN | [view interactions] | High throughput | no | yes |
| RAP2A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ADDG_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PUR6_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ITPR2_HUMAN | [view interactions] | High throughput | no | yes |
| PPIA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NCKP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SRSF3_HUMAN | [view interactions] | High throughput | no | yes |
| PUF60_HUMAN | [view interactions] | High throughput | no | yes |
| GRIA1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SPTA1_HUMAN | [view interactions] | High throughput | no | no |
| GRIA4_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| MARK1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| G3BP2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SSBP_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RAB5A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MYPT1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FCHO2_HUMAN | [view interactions] | High throughput | no | yes |
| KC1E_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HS105_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| REPS1_HUMAN | [view interactions] | High throughput | no | yes |
| BDH_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CATA_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| PFKAL_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GABR2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FA98A_HUMAN | [view interactions] | High throughput | no | no |
| ATPO_HUMAN | [view interactions] | High throughput | no | yes |
| MAG_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| WDR47_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LTMD1_HUMAN | [view interactions] | High throughput | no | no |
| RHG32_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HTRA1_HUMAN | [view interactions] | High throughput | no | yes |
| C170B_HUMAN | [view interactions] | High throughput | no | yes |
| CP250_HUMAN | [view interactions] | High throughput | no | no |
| TPM3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NEGR1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SPAS2_HUMAN | [view interactions] | High throughput | no | yes |
| ACSL3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LRRC7_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CPT1A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TRAF3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MYO1C_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| BEGIN_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CLIP2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DLGP4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DNJA3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DLG4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TPH2_HUMAN | [view interactions] | High throughput | no | no |
| SI1L1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| S2533_HUMAN | [view interactions] | High throughput | no | yes |
| ATP9A_HUMAN | [view interactions] | High throughput | no | yes |
| CDK18_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RHG23_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DJC11_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| KCAB2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NMDE1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KCC2B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TMCC3_HUMAN | [view interactions] | High throughput | no | yes |
| KC1A_HUMAN | [view interactions] | High throughput | no | yes |
| DNJB6_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CNTP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TRI32_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| VP13C_HUMAN | [view interactions] | High throughput | no | yes |
| XPP3_HUMAN | [view interactions] | High throughput | no | yes |
| GULP1_HUMAN | [view interactions] | High throughput | no | no |
| PCBP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RHG26_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SRBS2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| LRCH1_HUMAN | [view interactions] | High throughput | no | yes |
| BAIP2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NFL_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AGK_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MARE2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DLG3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| STK39_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ELAV4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MTCH1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GRIA3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AP1B1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PPR29_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MAGI2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CBPE_HUMAN | [view interactions] | High throughput | no | yes |
| YES_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SYT5_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| DLGP1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| DTNA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PGAM5_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ACTN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ACK1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CFTR_HUMAN | [view interactions] | High throughput | no | no |
| ZO2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ELAV2_HUMAN | [view interactions] | High throughput | no | yes |
| ABLM3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NUMB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FBX41_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| F120C_HUMAN | [view interactions] | High throughput | no | yes |
| SHAN3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| KCTD8_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CTNB1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| BTBDH_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| MY18A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| VATB2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ITIH1_HUMAN | [view interactions] | High throughput | no | no |
| ARPC3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FARP1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RAB18_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NFH_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SMC5_HUMAN | [view interactions] | High throughput | no | yes |
| CACO1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NCAN_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| SCMC2_HUMAN | [view interactions] | High throughput | no | yes |
| KCNA4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| STML2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RPGF2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| SRGP3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FRPD1_HUMAN | [view interactions] | High throughput | no | yes |
| MYO9A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PABP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SC6A4_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CNRP1_HUMAN | [view interactions] | High throughput | no | no |
| MARE3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GABR1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| THEM6_HUMAN | [view interactions] | High throughput | no | no |
| ARPC2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| C1TC_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MYL6_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RHG21_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CTNA3_HUMAN | [view interactions] | High throughput | no | no |
| AMPD3_HUMAN | [view interactions] | High throughput | no | no |
| CHM4C_HUMAN | [view interactions] | High throughput | no | yes |
| RN222_HUMAN | [view interactions] | High throughput | no | no |
| THIO_HUMAN | [view interactions] | High throughput | no | yes |
| ARP2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AT2B1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GBB1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DGKZ_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SYT11_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PDCD6_HUMAN | [view interactions] | High throughput | no | no |
| DLGP3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ALG2_HUMAN | [view interactions] | High throughput | no | yes |
| VIME_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| MFR1L_HUMAN | [view interactions] | High throughput | no | yes |
| MTMR5_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| DYL1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| TENA_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| GLRB_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| LIPA3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KCNQ2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ADCK1_HUMAN | [view interactions] | High throughput | no | no |
| KCJ10_HUMAN | [view interactions] | High throughput | no | no |
| HIP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ABTB3_HUMAN | [view interactions] | High throughput | no | no |
| SGIP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PP1A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DLG2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HACD3_HUMAN | [view interactions] | High throughput | no | yes |
| SCAI_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GSK3B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SRBS1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MIB2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SRRM1_HUMAN | [view interactions] | High throughput | no | yes |
| PPT1_HUMAN | [view interactions] | High throughput | no | yes |
| PURA_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| KCD12_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| BMP2K_HUMAN | [view interactions] | High throughput | no | yes |
| PHB1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ACSL6_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ARP3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AGAP2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SRC8_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ABCD3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DCAF7_HUMAN | [view interactions] | High throughput | no | yes |
| IQEC1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RP3A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HOME1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HPLN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DGKE_HUMAN | [view interactions] | High throughput | no | yes |
| LANC1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GFAP_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| WFS1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PTCD3_HUMAN | [view interactions] | High throughput | no | yes |
| CLD11_HUMAN | [view interactions] | High throughput | no | no |
| NFM_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MPC2_HUMAN | [view interactions] | High throughput | no | yes |
| TENR_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| LONP2_HUMAN | [view interactions] | High throughput | no | yes |
| AP3B2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PHB2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GAK_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KC1D_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| M2OM_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CCD15_HUMAN | [view interactions] | High throughput | no | no |
| KCTD3_HUMAN | [view interactions] | High throughput | no | yes |
| NDUA4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CAPZB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ANS1B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CSKP_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ARPC4_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| MARK3_HUMAN | [view interactions] | High throughput | no | yes |
| ADDB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AMD_HUMAN | [view interactions] | High throughput | no | yes |
| ARF3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RFIP2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MTX2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CADH2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| PISD_HUMAN | [view interactions] | High throughput | no | yes |
| EF2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| STXB5_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| 1433G_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RUN3A_HUMAN | [view interactions] | High throughput | no | yes |
| GIT1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CAZA2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RGPA1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| VDAC3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| JPH3_HUMAN | [view interactions] | High throughput | no | no |
| DDR1_HUMAN | [view interactions] | High throughput | no | yes |
| DC2I1_HUMAN | [view interactions] | High throughput | no | yes |
| AP2S1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| NEB2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| EAA1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| MRCKB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| QCR8_HUMAN | [view interactions] | High throughput | no | yes |
| EPS15_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DYL2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| PARD3_HUMAN | [view interactions] | High throughput | no | yes |
| ADT2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PALM_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DBNL_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GRIA2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ACTA_HUMAN | [view interactions] | High throughput | no | no |
| AP3D1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| LIFR_HUMAN | [view interactions] | High throughput | no | no |
| GDAP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FLOT1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| EXOG_HUMAN | [view interactions] | High throughput | no | yes |
| M3K13_HUMAN | [view interactions] | High throughput | no | yes |
| MARK4_HUMAN | [view interactions] | High throughput | no | yes |
| RIGI_HUMAN | [view interactions] | High throughput | no | yes |
| PPIB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ACTY_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| TGM2_HUMAN | [view interactions] | High throughput | no | no |
| EPIPL_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CPSF2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NPTX1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NF1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| DPYL1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ELP1_HUMAN | [view interactions] | High throughput | no | yes |
| GNL3_HUMAN | [view interactions] | High throughput | no | yes |
| COR2A_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ARL6_HUMAN | [view interactions] | High throughput | no | yes |
| HERC2_HUMAN | [view interactions] | High throughput | no | yes |
| MK03_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LARP1_HUMAN | [view interactions] | High throughput | no | yes |
| RHG39_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| IF4B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TNIK_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AMOL1_HUMAN | [view interactions] | High throughput | no | no |
| AGRB2_HUMAN | [view interactions] | High throughput | no | no |
| PBIP1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| TRI46_HUMAN | [view interactions] | High throughput | no | no |
| CLAP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NLGN2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DRS7B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FN3K_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| SERA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| OPA3_HUMAN | [view interactions] | High throughput | no | yes |
| ACBG1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| USP9X_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ERBIN_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| L2GL1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NCDN_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CTND1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CERK1_HUMAN | [view interactions] | High throughput | no | no |
| SYT6_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RAI14_HUMAN | [view interactions] | High throughput | no | yes |
| HSDL1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| C1TM_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SCOT1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |