Features Interactions Isoform Disease Linear motifs Fingerprint Network All partners

DGKB_HUMAN

Evidence for PS localization

GO
G2C
SynGO
SynaptomeDB

Functions

Does not associate with membranes but has a diacylglycerol kinase activity. [View more on UniProt]

Protein features

Binary interactions with known binding regions

Interacting region for partners were not defined.

Network

Download full PS network for entry.

Isoforms

Disease-causing germline mutations

No data found.

Linear motifs

No annotated instance was found. To search for linear motifs, use the ELM prediction server.

Fingerprint

Molecular function

Term Name % Distance from the top of the tree Annotated in DGKB_HUMAN
GO:0000166 nucleotide binding 75.0000 4 yes
GO:0005524 ATP binding 75.0000 5 yes
GO:0016301 kinase activity 75.0000 4 yes
GO:0016773 phosphotransferase activity, alcohol group as acceptor 75.0000 4 yes
GO:0017076 purine nucleotide binding 75.0000 5 yes
GO:0030554 adenyl nucleotide binding 75.0000 6 yes
GO:0032555 purine ribonucleotide binding 75.0000 4 yes
GO:0032559 adenyl ribonucleotide binding 75.0000 5 yes
GO:0035639 purine ribonucleoside triphosphate binding 75.0000 4 yes
GO:0043168 anion binding 75.0000 4 yes
GO:0043169 cation binding 75.0000 4 yes
GO:0046872 metal ion binding 75.0000 5 yes
GO:0004674 protein serine/threonine kinase activity 50.0000 4 no
GO:0106310 protein serine kinase activity 50.0000 4 no

Biological process

Term Name % Distance from top the of the tree Annotated in DGKB_HUMAN
GO:0060255 regulation of macromolecule metabolic process 75.0000 4 no
GO:0071310 cellular response to organic substance 75.0000 4 no
GO:0099177 regulation of trans-synaptic signaling 75.0000 4 no
GO:0006796 phosphate-containing compound metabolic process 75.0000 4 yes
GO:0016310 phosphorylation 75.0000 5 yes
GO:0009889 regulation of biosynthetic process 75.0000 4 no
GO:0010556 regulation of macromolecule biosynthetic process 75.0000 5 no
GO:0010646 regulation of cell communication 75.0000 4 no
GO:0031323 regulation of cellular metabolic process 75.0000 4 no
GO:0031326 regulation of cellular biosynthetic process 75.0000 5 no
GO:0048522 positive regulation of cellular process 75.0000 4 no
GO:0050804 modulation of chemical synaptic transmission 75.0000 5 no
GO:0051049 regulation of transport 75.0000 4 no
GO:0071345 cellular response to cytokine stimulus 50.0000 5 no
GO:0080090 regulation of primary metabolic process 50.0000 4 no
GO:0098657 import into cell 50.0000 4 no
GO:1901701 cellular response to oxygen-containing compound 50.0000 4 no
GO:2000145 regulation of cell motility 50.0000 4 no
GO:0006811 monoatomic ion transport 50.0000 4 no
GO:0006812 monoatomic cation transport 50.0000 5 no
GO:0010468 regulation of gene expression 50.0000 6 no
GO:0030001 metal ion transport 50.0000 6 no
GO:0043269 regulation of monoatomic ion transport 50.0000 5 no
GO:0043270 positive regulation of monoatomic ion transport 50.0000 5 no
GO:0051046 regulation of secretion 50.0000 5 no
GO:0051050 positive regulation of transport 50.0000 4 no
GO:1903530 regulation of secretion by cell 50.0000 4 no
GO:0006468 protein phosphorylation 50.0000 5 no
GO:0009891 positive regulation of biosynthetic process 50.0000 5 no
GO:0009893 positive regulation of metabolic process 50.0000 4 no
GO:0009966 regulation of signal transduction 50.0000 4 no
GO:0010557 positive regulation of macromolecule biosynthetic process 50.0000 6 no
GO:0010604 positive regulation of macromolecule metabolic process 50.0000 5 no
GO:0010647 positive regulation of cell communication 50.0000 5 no
GO:0014070 response to organic cyclic compound 50.0000 4 no
GO:0018105 peptidyl-serine phosphorylation 50.0000 6 no
GO:0018107 peptidyl-threonine phosphorylation 50.0000 6 no
GO:0018193 peptidyl-amino acid modification 50.0000 5 no
GO:0018209 peptidyl-serine modification 50.0000 6 no
GO:0018210 peptidyl-threonine modification 50.0000 6 no
GO:0019219 regulation of nucleobase-containing compound metabolic process 50.0000 5 no
GO:0023056 positive regulation of signaling 50.0000 4 no
GO:0030334 regulation of cell migration 50.0000 5 no
GO:0031325 positive regulation of cellular metabolic process 50.0000 5 no
GO:0031328 positive regulation of cellular biosynthetic process 50.0000 6 no
GO:0034097 response to cytokine 50.0000 4 no
GO:0036211 protein modification process 50.0000 4 no
GO:0042127 regulation of cell population proliferation 50.0000 4 no
GO:0043412 macromolecule modification 50.0000 4 no
GO:0045595 regulation of cell differentiation 50.0000 4 no
GO:0045596 negative regulation of cell differentiation 50.0000 5 no
GO:0048523 negative regulation of cellular process 50.0000 4 no
GO:0048584 positive regulation of response to stimulus 50.0000 4 no
GO:0050890 cognition 50.0000 4 no
GO:0051093 negative regulation of developmental process 50.0000 4 no

Disease

No data found.

All partners

Uniprot ID Details Highest evidence Localizing into PSD HPA (protein expression in neurons)
PCDB5_HUMAN [view entry] [view interactions] High throughput yes no
K1H1_HUMAN [view interactions] High throughput no no
MK01_HUMAN [view entry] [view interactions] High throughput yes yes
KCC2A_HUMAN [view entry] [view interactions] High throughput yes yes
SC6A4_HUMAN [view entry] [view interactions] High throughput yes no
DGKE_HUMAN [view interactions] High throughput no yes
SSR3_HUMAN [view interactions] High throughput no yes