MTCH1_HUMAN
Evidence for PS localization
Functions
Potential mitochondrial transporter. May play a role in apoptosis. [View more on UniProt]
Protein features
Binary interactions with known binding regions
Interacting region for partners were not defined.
Network
Isoforms
Disease-causing germline mutations
No data found.
Linear motifs
No annotated instance was found. To search for linear motifs, use the ELM prediction server.
Fingerprint
Molecular function
| Term | Name | % | Distance from the top of the tree | Annotated in MTCH1_HUMAN |
|---|---|---|---|---|
| GO:0017076 | purine nucleotide binding | 33.3333 | 4 | no |
| GO:0032555 | purine ribonucleotide binding | 33.3333 | 4 | no |
| GO:0035639 | purine ribonucleoside triphosphate binding | 28.9855 | 4 | no |
| GO:0030554 | adenyl nucleotide binding | 24.6377 | 5 | no |
| GO:0032559 | adenyl ribonucleotide binding | 24.6377 | 5 | no |
| GO:0046872 | metal ion binding | 21.7391 | 4 | no |
| GO:0005524 | ATP binding | 20.2899 | 5 | no |
Biological process
| Term | Name | % | Distance from top the of the tree | Annotated in MTCH1_HUMAN |
|---|---|---|---|---|
| GO:0006996 | organelle organization | 36.2319 | 4 | no |
| GO:0048523 | negative regulation of cellular process | 33.3333 | 4 | no |
| GO:0048522 | positive regulation of cellular process | 31.8841 | 4 | yes |
| GO:0060255 | regulation of macromolecule metabolic process | 30.4348 | 4 | yes |
| GO:0080090 | regulation of primary metabolic process | 27.5362 | 4 | yes |
| GO:0031323 | regulation of cellular metabolic process | 27.5362 | 4 | no |
| GO:0010646 | regulation of cell communication | 26.0870 | 4 | yes |
| GO:0051171 | regulation of nitrogen compound metabolic process | 26.0870 | 4 | yes |
| GO:0061024 | membrane organization | 26.0870 | 4 | yes |
| GO:0051128 | regulation of cellular component organization | 26.0870 | 4 | no |
| GO:0009893 | positive regulation of metabolic process | 24.6377 | 4 | yes |
| GO:0051246 | regulation of protein metabolic process | 23.1884 | 5 | yes |
| GO:0009966 | regulation of signal transduction | 21.7391 | 4 | yes |
| GO:0010941 | regulation of cell death | 21.7391 | 4 | yes |
| GO:0022607 | cellular component assembly | 21.7391 | 4 | no |
| GO:0010604 | positive regulation of macromolecule metabolic process | 20.2899 | 5 | yes |
| GO:0042981 | regulation of apoptotic process | 20.2899 | 6 | yes |
| GO:0043067 | regulation of programmed cell death | 20.2899 | 5 | yes |
| GO:0007005 | mitochondrion organization | 20.2899 | 5 | no |
| GO:0051049 | regulation of transport | 20.2899 | 4 | no |
| GO:0009894 | regulation of catabolic process | 20.2899 | 4 | no |
| GO:0010468 | regulation of gene expression | 20.2899 | 5 | no |
| GO:0051173 | positive regulation of nitrogen compound metabolic process | 17.3913 | 5 | yes |
| GO:0051247 | positive regulation of protein metabolic process | 15.9420 | 6 | yes |
| GO:0006915 | apoptotic process | 11.5942 | 4 | yes |
| GO:0043085 | positive regulation of catalytic activity | 10.1449 | 4 | yes |
| GO:0010942 | positive regulation of cell death | 8.6957 | 5 | yes |
| GO:0030162 | regulation of proteolysis | 8.6957 | 6 | yes |
| GO:0043065 | positive regulation of apoptotic process | 8.6957 | 7 | yes |
| GO:0043068 | positive regulation of programmed cell death | 8.6957 | 6 | yes |
| GO:0045862 | positive regulation of proteolysis | 7.2464 | 7 | yes |
| GO:0051336 | regulation of hydrolase activity | 5.7971 | 4 | yes |
| GO:0051345 | positive regulation of hydrolase activity | 5.7971 | 5 | yes |
| GO:0010952 | positive regulation of peptidase activity | 2.8986 | 6 | yes |
| GO:0052547 | regulation of peptidase activity | 2.8986 | 5 | yes |
Disease
| Term | Name | % | Distance from top the of the tree | Annotated in MTCH1_HUMAN |
|---|---|---|---|---|
| DOID:574 | peripheral nervous system disease | 5.7971 | 3 | no |
| DOID:870 | neuropathy | 5.7971 | 4 | no |
| DOID:440 | neuromuscular disease | 4.3478 | 5 | no |
| DOID:10595 | Charcot-Marie-Tooth disease | 4.3478 | 6 | no |
| DOID:0050539 | Charcot-Marie-Tooth disease type 2 | 2.8986 | 7 | no |
| DOID:0060038 | specific developmental disorder | 2.8986 | 3 | no |
| DOID:1059 | intellectual disability | 2.8986 | 4 | no |
All partners
| Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
|---|---|---|---|---|
| PSN1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| PRS6B_HUMAN | [view interactions] | High throughput | no | yes |
| PRS10_HUMAN | [view interactions] | High throughput | no | yes |
| PSD11_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PSDE_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PSMD3_HUMAN | [view interactions] | High throughput | no | yes |
| PSMD7_HUMAN | [view interactions] | High throughput | no | yes |
| SDHA_HUMAN | [view interactions] | High throughput | no | yes |
| MPCP_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| TOM40_HUMAN | [view interactions] | High throughput | no | yes |
| NDUS1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| NDUV1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PRS7_HUMAN | [view interactions] | High throughput | no | yes |
| PRS6A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PSMD2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RPN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TOM22_HUMAN | [view interactions] | High throughput | no | yes |
| TPM3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| VDAC1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| VDAC2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| VDAC3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MARH2_HUMAN | [view interactions] | High throughput | no | yes |
| ABCD3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ACBD5_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ACOT2_HUMAN | [view interactions] | High throughput | no | yes |
| ACSL4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AFG32_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AKAP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AL3A2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| APC7_HUMAN | [view interactions] | High throughput | no | yes |
| APOL2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ARGL1_HUMAN | [view interactions] | High throughput | no | yes |
| ARM10_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ARMX3_HUMAN | [view interactions] | High throughput | no | no |
| ATD3A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ATD3B_HUMAN | [view interactions] | High throughput | no | yes |
| ATPF1_HUMAN | [view interactions] | High throughput | no | yes |
| B2L13_HUMAN | [view interactions] | High throughput | no | no |
| BNIP3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| BNI3L_HUMAN | [view interactions] | High throughput | no | yes |
| CI072_HUMAN | [view interactions] | High throughput | no | no |
| CYBP_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CDC23_HUMAN | [view interactions] | High throughput | no | yes |
| MIC19_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CHMP7_HUMAN | [view interactions] | High throughput | no | yes |
| CISD1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CRBG3_HUMAN | [view interactions] | High throughput | no | no |
| NB5R3_HUMAN | [view interactions] | High throughput | no | yes |
| DEP1B_HUMAN | [view interactions] | High throughput | no | yes |
| DNJA2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DJC11_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| DNJC7_HUMAN | [view interactions] | High throughput | no | yes |
| DNM1L_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| EHBP1_HUMAN | [view interactions] | High throughput | no | yes |
| ELOB_HUMAN | [view interactions] | High throughput | no | no |
| EXD2_HUMAN | [view interactions] | High throughput | no | yes |
| FAF2_HUMAN | [view interactions] | High throughput | no | yes |
| FBXL4_HUMAN | [view interactions] | High throughput | no | yes |
| FKBP4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FKBP8_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FUND2_HUMAN | [view interactions] | High throughput | no | yes |
| GLPK_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| GBB4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GOGA3_HUMAN | [view interactions] | High throughput | no | yes |
| HXK1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HXK2_HUMAN | [view interactions] | High throughput | no | yes |
| HSDL1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| MIC60_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| INF2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LARP4_HUMAN | [view interactions] | High throughput | no | yes |
| LMF2_HUMAN | [view interactions] | High throughput | no | yes |
| MAVS_HUMAN | [view interactions] | High throughput | no | yes |
| MFF_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MFN1_HUMAN | [view interactions] | High throughput | no | yes |
| MFN2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MID51_HUMAN | [view interactions] | High throughput | no | no |
| MIGA1_HUMAN | [view interactions] | High throughput | no | yes |
| MLX_HUMAN | [view interactions] | High throughput | no | yes |
| MTFR1_HUMAN | [view interactions] | High throughput | no | yes |
| MFR1L_HUMAN | [view interactions] | High throughput | no | yes |
| MTFR2_HUMAN | [view interactions] | High throughput | no | no |
| MTX2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MTX3_HUMAN | [view interactions] | High throughput | no | yes |
| MYO19_HUMAN | [view interactions] | High throughput | no | yes |
| NBR1_HUMAN | [view interactions] | High throughput | no | yes |
| NDUS2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NDUS7_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| NDKB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NUDC3_HUMAN | [view interactions] | High throughput | no | yes |
| OCAD1_HUMAN | [view interactions] | High throughput | no | yes |
| PHLP_HUMAN | [view interactions] | High throughput | no | yes |
| PEX1_HUMAN | [view interactions] | High throughput | no | no |
| PEX14_HUMAN | [view interactions] | High throughput | no | yes |
| PEX19_HUMAN | [view interactions] | High throughput | no | yes |
| PEX5_HUMAN | [view interactions] | High throughput | no | yes |
| PGRC2_HUMAN | [view interactions] | High throughput | no | yes |
| POTEE_HUMAN | [view interactions] | High throughput | no | no |
| KAP2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KAP3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KPCD_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KPCT_HUMAN | [view interactions] | High throughput | no | no |
| PTN1_HUMAN | [view interactions] | High throughput | no | yes |
| RAB1A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RAB3B_HUMAN | [view interactions] | High throughput | no | no |
| RAB7A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MIRO2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SAR1B_HUMAN | [view interactions] | High throughput | no | yes |
| ZNT9_HUMAN | [view interactions] | High throughput | no | yes |
| SMCR8_HUMAN | [view interactions] | High throughput | no | yes |
| SIM12_HUMAN | [view interactions] | High throughput | no | yes |
| SNP29_HUMAN | [view interactions] | High throughput | no | yes |
| SNP47_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| F10A1_HUMAN | [view interactions] | High throughput | no | yes |
| STIP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CHIP_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SGT1_HUMAN | [view interactions] | High throughput | no | no |
| TACC1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TDRKH_HUMAN | [view interactions] | High throughput | no | no |
| TOM5_HUMAN | [view interactions] | High throughput | no | yes |
| TOM70_HUMAN | [view interactions] | High throughput | no | yes |
| TRABD_HUMAN | [view interactions] | High throughput | no | yes |
| TRAK1_HUMAN | [view interactions] | High throughput | no | yes |
| TXNL1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| UBXN4_HUMAN | [view interactions] | High throughput | no | yes |
| UBP30_HUMAN | [view interactions] | High throughput | no | yes |
| VP13A_HUMAN | [view interactions] | High throughput | no | yes |
| VP13D_HUMAN | [view interactions] | High throughput | no | no |
| WDR41_HUMAN | [view interactions] | High throughput | no | yes |
| YKT6_HUMAN | [view interactions] | High throughput | no | yes |
| GSK3A_HUMAN | [view interactions] | High throughput | no | yes |
| HIF1N_HUMAN | [view interactions] | High throughput | no | yes |
| TIDC1_HUMAN | [view interactions] | High throughput | no | yes |
| NMES1_HUMAN | [view interactions] | High throughput | no | no |
| RAC1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| EDEM1_HUMAN | [view interactions] | High throughput | no | yes |
| HSC20_HUMAN | [view interactions] | High throughput | no | yes |
| APJ_HUMAN | [view interactions] | High throughput | no | yes |
| SMAD2_HUMAN | [view interactions] | High throughput | no | yes |
| ERBB2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| NRG1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| SLAF1_HUMAN | [view interactions] | High throughput | no | no |
| VSIG4_HUMAN | [view interactions] | High throughput | no | no |
| UBP7_HUMAN | [view interactions] | High throughput | no | yes |
| TRI26_HUMAN | [view interactions] | High throughput | no | yes |
| SOSB1_HUMAN | [view interactions] | High throughput | no | yes |
| NLRP3_HUMAN | [view interactions] | High throughput | no | yes |
| RMD3_HUMAN | [view interactions] | High throughput | no | yes |
| S2546_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DUS22_HUMAN | [view interactions] | High throughput | no | yes |
| DUS28_HUMAN | [view interactions] | High throughput | no | yes |
| SPP2B_HUMAN | [view interactions] | High throughput | no | yes |
| SCN3B_HUMAN | [view interactions] | High throughput | no | no |
| TOIP2_HUMAN | [view interactions] | High throughput | no | no |
| TSN2_HUMAN | [view interactions] | High throughput | no | no |
| RIC8A_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| IMDH1_HUMAN | [view interactions] | High throughput | no | yes |
| TECT2_HUMAN | [view interactions] | High throughput | no | yes |
| EGLN3_HUMAN | [view interactions] | High throughput | no | no |
| FGFR1_HUMAN | [view interactions] | High throughput | no | yes |
| RNF4_HUMAN | [view interactions] | High throughput | no | yes |
| LMBRL_HUMAN | [view interactions] | High throughput | no | no |
| INS_HUMAN | [view interactions] | High throughput | no | no |
| SC6A4_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| UFL1_HUMAN | [view interactions] | High throughput | no | yes |
| DDRGK_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LRC55_HUMAN | [view interactions] | High throughput | no | yes |
| SYPH_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TGFA_HUMAN | [view interactions] | High throughput | no | yes |
| S22A9_HUMAN | [view interactions] | High throughput | no | no |
| TACD2_HUMAN | [view interactions] | High throughput | no | no |
| VSIG1_HUMAN | [view interactions] | High throughput | no | no |
| CLC2B_HUMAN | [view interactions] | High throughput | no | yes |
| CYB5B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SPRTN_HUMAN | [view interactions] | High throughput | no | yes |
| HNRPU_HUMAN | [view interactions] | High throughput | no | yes |
| LTOR3_HUMAN | [view interactions] | High throughput | no | yes |
| FGOP2_HUMAN | [view interactions] | High throughput | no | yes |
| EWS_HUMAN | [view interactions] | High throughput | no | yes |
| ABCB7_HUMAN | [view interactions] | High throughput | no | yes |
| AT1A1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ATPD_HUMAN | [view interactions] | High throughput | no | yes |
| VA0D1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AT1B1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| AT1B3_HUMAN | [view interactions] | High throughput | no | yes |
| ATPA_HUMAN | [view interactions] | High throughput | no | yes |
| AT5F1_HUMAN | [view interactions] | High throughput | no | yes |
| ATP5L_HUMAN | [view interactions] | High throughput | no | yes |
| ATPO_HUMAN | [view interactions] | High throughput | no | yes |
| FAS_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| HACL2_HUMAN | [view interactions] | High throughput | no | yes |
| PRP19_HUMAN | [view interactions] | High throughput | no | yes |
| PRS4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |