ACBD5_HUMAN
Evidence for PS localization
Functions
Acyl-CoA binding protein which acts as the peroxisome receptor for pexophagy but is dispensable for aggrephagy and nonselective autophagy. Binds medium- and long-chain acyl-CoA esters. [View more on UniProt]
Protein features
Binary interactions with known binding regions
Interacting region for partners were not defined.
Network
Isoforms
Disease-causing germline mutations
No data found.
Linear motifs
No annotated instance was found. To search for linear motifs, use the ELM prediction server.
Fingerprint
Molecular function
| Term | Name | % | Distance from the top of the tree | Annotated in ACBD5_HUMAN |
|---|---|---|---|---|
| GO:0000166 | nucleotide binding | 38.0282 | 4 | yes |
| GO:0017076 | purine nucleotide binding | 38.0282 | 5 | yes |
| GO:0032555 | purine ribonucleotide binding | 36.6197 | 4 | yes |
| GO:0043168 | anion binding | 36.6197 | 4 | yes |
| GO:0035639 | purine ribonucleoside triphosphate binding | 35.2113 | 4 | no |
| GO:0016462 | pyrophosphatase activity | 29.5775 | 5 | no |
| GO:0016818 | hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides | 29.5775 | 4 | no |
| GO:0017111 | ribonucleoside triphosphate phosphatase activity | 29.5775 | 6 | no |
| GO:0043169 | cation binding | 21.1268 | 4 | no |
| GO:0046872 | metal ion binding | 21.1268 | 5 | no |
| GO:0030554 | adenyl nucleotide binding | 19.7183 | 6 | yes |
| GO:0032559 | adenyl ribonucleotide binding | 18.3099 | 5 | yes |
Biological process
| Term | Name | % | Distance from top the of the tree | Annotated in ACBD5_HUMAN |
|---|---|---|---|---|
| GO:0048522 | positive regulation of cellular process | 46.4789 | 4 | no |
| GO:0008104 | protein localization | 40.8451 | 4 | no |
| GO:0006996 | organelle organization | 39.4366 | 4 | no |
| GO:0010646 | regulation of cell communication | 35.2113 | 4 | no |
| GO:0060255 | regulation of macromolecule metabolic process | 35.2113 | 4 | no |
| GO:0071702 | organic substance transport | 33.8028 | 4 | no |
| GO:0071705 | nitrogen compound transport | 30.9859 | 4 | no |
| GO:0009966 | regulation of signal transduction | 29.5775 | 4 | no |
| GO:0031323 | regulation of cellular metabolic process | 29.5775 | 4 | no |
| GO:0080090 | regulation of primary metabolic process | 29.5775 | 4 | no |
| GO:0048523 | negative regulation of cellular process | 28.1690 | 4 | no |
| GO:0051128 | regulation of cellular component organization | 28.1690 | 4 | no |
| GO:0009893 | positive regulation of metabolic process | 26.7606 | 4 | no |
| GO:0010604 | positive regulation of macromolecule metabolic process | 26.7606 | 5 | no |
| GO:0015031 | protein transport | 26.7606 | 4 | no |
| GO:0051246 | regulation of protein metabolic process | 25.3521 | 5 | no |
| GO:0023056 | positive regulation of signaling | 23.9437 | 4 | no |
| GO:0048584 | positive regulation of response to stimulus | 23.9437 | 4 | no |
| GO:0051049 | regulation of transport | 23.9437 | 4 | no |
| GO:0061024 | membrane organization | 23.9437 | 4 | no |
| GO:0010647 | positive regulation of cell communication | 22.5352 | 5 | no |
| GO:0009967 | positive regulation of signal transduction | 21.1268 | 5 | no |
| GO:0022607 | cellular component assembly | 21.1268 | 4 | no |
| GO:0044087 | regulation of cellular component biogenesis | 21.1268 | 4 | no |
| GO:0009889 | regulation of biosynthetic process | 21.1268 | 4 | no |
| GO:0010556 | regulation of macromolecule biosynthetic process | 21.1268 | 5 | no |
| GO:0031326 | regulation of cellular biosynthetic process | 21.1268 | 5 | no |
| GO:0019752 | carboxylic acid metabolic process | 7.0423 | 5 | yes |
| GO:0032787 | monocarboxylic acid metabolic process | 7.0423 | 6 | yes |
| GO:0043436 | oxoacid metabolic process | 7.0423 | 4 | yes |
| GO:0006631 | fatty acid metabolic process | 4.2254 | 4 | yes |
Disease
No data found.
All partners
| Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
|---|---|---|---|---|
| CNOT3_HUMAN | [view interactions] | High throughput | no | yes |
| DHCR7_HUMAN | [view interactions] | High throughput | no | yes |
| GRIA1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GRIA2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LNP_HUMAN | [view interactions] | High throughput | no | yes |
| NRX1A_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| SC6A1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| SPAST_HUMAN | [view interactions] | High throughput | no | yes |
| RAB18_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RFA2_HUMAN | [view interactions] | High throughput | no | yes |
| RFA3_HUMAN | [view interactions] | High throughput | no | yes |
| VAPA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| BMI1_HUMAN | [view interactions] | High throughput | no | yes |
| CNDD3_HUMAN | [view interactions] | High throughput | no | no |
| ESR1_HUMAN | [view interactions] | High throughput | no | no |
| CALX_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| COX14_HUMAN | [view interactions] | High throughput | no | yes |
| TOM20_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TOM22_HUMAN | [view interactions] | High throughput | no | yes |
| CNEP1_HUMAN | [view interactions] | High throughput | no | yes |
| CFTR_HUMAN | [view interactions] | High throughput | no | no |
| STX1B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| S38A7_HUMAN | [view interactions] | High throughput | no | yes |
| GRM2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| T229B_HUMAN | [view interactions] | High throughput | no | yes |
| FBW1B_HUMAN | [view interactions] | High throughput | no | yes |
| MOV10_HUMAN | [view interactions] | High throughput | no | no |
| NXF1_HUMAN | [view interactions] | High throughput | no | yes |
| VAPB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RAB5C_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PRP4_HUMAN | [view interactions] | High throughput | no | yes |
| GOT1B_HUMAN | [view interactions] | High throughput | no | yes |
| MYO5C_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GWL_HUMAN | [view interactions] | High throughput | no | yes |
| EMC5_HUMAN | [view interactions] | High throughput | no | yes |
| KLC3_HUMAN | [view interactions] | High throughput | no | no |
| NEDD1_HUMAN | [view interactions] | High throughput | no | yes |
| RMD3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CP135_HUMAN | [view interactions] | High throughput | no | no |
| CNGA3_HUMAN | [view interactions] | High throughput | no | no |
| ZFPL1_HUMAN | [view interactions] | High throughput | no | yes |
| NECA2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HIF1N_HUMAN | [view interactions] | High throughput | no | yes |
| EGLN3_HUMAN | [view interactions] | High throughput | no | no |
| KIF14_HUMAN | [view interactions] | High throughput | no | no |
| UBQL2_HUMAN | [view interactions] | High throughput | no | yes |
| EDEM1_HUMAN | [view interactions] | High throughput | no | yes |
| PRD11_HUMAN | [view interactions] | High throughput | no | yes |
| BCL2_HUMAN | [view interactions] | High throughput | no | no |
| RHOG_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RHOA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CDC42_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RAC3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RHOC_HUMAN | [view interactions] | High throughput | no | no |
| RND2_HUMAN | [view interactions] | High throughput | no | no |
| RAC2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TRI67_HUMAN | [view interactions] | High throughput | no | no |
| ABCBA_HUMAN | [view interactions] | High throughput | no | yes |
| ADAS_HUMAN | [view interactions] | High throughput | no | yes |
| HAT1_HUMAN | [view interactions] | High throughput | no | yes |
| FBW1A_HUMAN | [view interactions] | High throughput | no | yes |
| RHBL4_HUMAN | [view interactions] | High throughput | no | no |
| OTULL_HUMAN | [view interactions] | High throughput | no | no |
| ST7_HUMAN | [view interactions] | High throughput | no | yes |
| EXD2_HUMAN | [view interactions] | High throughput | no | yes |
| FIS1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FKBP8_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HAX1_HUMAN | [view interactions] | High throughput | no | no |
| MARH5_HUMAN | [view interactions] | High throughput | no | no |
| MAVS_HUMAN | [view interactions] | High throughput | no | yes |
| MTCH1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| OCAD1_HUMAN | [view interactions] | High throughput | no | yes |
| PTN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MIRO2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| S2546_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SC61B_HUMAN | [view interactions] | High throughput | no | yes |
| DNJC1_HUMAN | [view interactions] | High throughput | no | yes |
| DJC25_HUMAN | [view interactions] | High throughput | no | yes |
| SEC63_HUMAN | [view interactions] | High throughput | no | yes |
| MARC2_HUMAN | [view interactions] | High throughput | no | no |
| ABCD3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ACBD4_HUMAN | [view interactions] | High throughput | no | no |
| ACTBL_HUMAN | [view interactions] | High throughput | no | no |
| AFG32_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AKAP9_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AL3A2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RHG01_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AUP1_HUMAN | [view interactions] | High throughput | no | yes |
| CE022_HUMAN | [view interactions] | High throughput | no | yes |
| CK5P2_HUMAN | [view interactions] | High throughput | no | yes |
| CDKAL_HUMAN | [view interactions] | High throughput | no | no |
| CNTRB_HUMAN | [view interactions] | High throughput | no | yes |
| CYB5B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DDRGK_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DGKH_HUMAN | [view interactions] | High throughput | no | yes |
| DIAP3_HUMAN | [view interactions] | High throughput | no | no |
| DNJA2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| EPS15_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FAP20_HUMAN | [view interactions] | High throughput | no | no |
| FAF2_HUMAN | [view interactions] | High throughput | no | yes |
| FLOT2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GASP2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HS71B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HS71A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HSP7C_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| IP6K1_HUMAN | [view interactions] | High throughput | no | yes |
| IPO4_HUMAN | [view interactions] | High throughput | no | no |
| GRRE1_HUMAN | [view interactions] | High throughput | no | no |
| KIF11_HUMAN | [view interactions] | High throughput | no | yes |
| KIF3A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LDHB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MAGD1_HUMAN | [view interactions] | High throughput | no | no |
| MIGA2_HUMAN | [view interactions] | High throughput | no | yes |
| N4BP2_HUMAN | [view interactions] | High throughput | no | yes |
| NBR1_HUMAN | [view interactions] | High throughput | no | yes |
| NCK5L_HUMAN | [view interactions] | High throughput | no | yes |
| NDC80_HUMAN | [view interactions] | High throughput | no | no |
| NELFD_HUMAN | [view interactions] | High throughput | no | yes |
| NFKB1_HUMAN | [view interactions] | High throughput | no | yes |
| NGLY1_HUMAN | [view interactions] | High throughput | no | yes |
| NUP58_HUMAN | [view interactions] | High throughput | no | yes |
| NUP62_HUMAN | [view interactions] | High throughput | no | yes |
| NUP88_HUMAN | [view interactions] | High throughput | no | yes |
| PCNT_HUMAN | [view interactions] | High throughput | no | yes |
| PEG10_HUMAN | [view interactions] | High throughput | no | no |
| PX11B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PEX13_HUMAN | [view interactions] | High throughput | no | yes |
| PEX14_HUMAN | [view interactions] | High throughput | no | yes |
| PEX16_HUMAN | [view interactions] | High throughput | no | yes |
| PEX19_HUMAN | [view interactions] | High throughput | no | yes |
| PEX3_HUMAN | [view interactions] | High throughput | no | yes |
| PEX5_HUMAN | [view interactions] | High throughput | no | yes |
| BCAP_HUMAN | [view interactions] | High throughput | no | no |
| PJA2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| P2R3A_HUMAN | [view interactions] | High throughput | no | yes |
| PP6R1_HUMAN | [view interactions] | High throughput | no | no |
| PRS7_HUMAN | [view interactions] | High throughput | no | yes |
| PRS6A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PRS6B_HUMAN | [view interactions] | High throughput | no | yes |
| PSMD1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PSMD4_HUMAN | [view interactions] | High throughput | no | yes |
| RAB1A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RD23A_HUMAN | [view interactions] | High throughput | no | yes |
| RMD2_HUMAN | [view interactions] | High throughput | no | yes |
| SGTA_HUMAN | [view interactions] | High throughput | no | yes |
| ZNT9_HUMAN | [view interactions] | High throughput | no | yes |
| NSMA3_HUMAN | [view interactions] | High throughput | no | yes |
| SNX7_HUMAN | [view interactions] | High throughput | no | yes |
| SPAG5_HUMAN | [view interactions] | High throughput | no | yes |
| F10A1_HUMAN | [view interactions] | High throughput | no | yes |
| STIP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CHIP_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TBKB1_HUMAN | [view interactions] | High throughput | no | no |
| THOC7_HUMAN | [view interactions] | High throughput | no | yes |
| TM131_HUMAN | [view interactions] | High throughput | no | yes |
| TM135_HUMAN | [view interactions] | High throughput | no | yes |
| LDAF1_HUMAN | [view interactions] | High throughput | no | yes |
| TRPS1_HUMAN | [view interactions] | High throughput | no | no |
| TTC1_HUMAN | [view interactions] | High throughput | no | yes |
| RL40_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| UB2J1_HUMAN | [view interactions] | High throughput | no | yes |
| UBL4A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| UBQL1_HUMAN | [view interactions] | High throughput | no | yes |
| UBQL4_HUMAN | [view interactions] | High throughput | no | yes |
| UBXN4_HUMAN | [view interactions] | High throughput | no | yes |
| UBP30_HUMAN | [view interactions] | High throughput | no | yes |
| VRK2_HUMAN | [view interactions] | High throughput | no | no |
| YKT6_HUMAN | [view interactions] | High throughput | no | yes |
| APC4_HUMAN | [view interactions] | High throughput | no | yes |
| CFA36_HUMAN | [view interactions] | High throughput | no | yes |
| COPA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| EIF3H_HUMAN | [view interactions] | High throughput | no | yes |
| EXOC4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GGA3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HXK1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| IMB1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MYL6_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| NP1L4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PGRC2_HUMAN | [view interactions] | High throughput | no | yes |
| SMCR8_HUMAN | [view interactions] | High throughput | no | yes |
| SNP29_HUMAN | [view interactions] | High throughput | no | yes |
| SYNE2_HUMAN | [view interactions] | High throughput | no | no |
| TBK1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| WAC2A_HUMAN | [view interactions] | High throughput | no | yes |
| WWOX_HUMAN | [view interactions] | High throughput | no | yes |
| YTHD2_HUMAN | [view interactions] | High throughput | no | yes |
| YTHD3_HUMAN | [view interactions] | High throughput | no | no |
| AKAP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AT2A1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CKAP4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DERL1_HUMAN | [view interactions] | High throughput | no | yes |
| ELOV5_HUMAN | [view interactions] | High throughput | no | yes |
| EMD_HUMAN | [view interactions] | High throughput | no | yes |
| DHB11_HUMAN | [view interactions] | High throughput | no | yes |
| 3BHS7_HUMAN | [view interactions] | High throughput | no | no |
| LRC59_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TMT1A_HUMAN | [view interactions] | High throughput | no | no |
| NU155_HUMAN | [view interactions] | High throughput | no | yes |
| PXMP2_HUMAN | [view interactions] | High throughput | no | no |
| RAB3B_HUMAN | [view interactions] | High throughput | no | no |
| RAB5A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RPN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RPN2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SEC62_HUMAN | [view interactions] | High throughput | no | yes |
| SSRA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| STIM1_HUMAN | [view interactions] | High throughput | no | yes |
| LAP2A_HUMAN | [view interactions] | High throughput | no | yes |
| RAB7A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| STING_HUMAN | [view interactions] | High throughput | no | yes |
| ARF6_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SAR1A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ARL5A_HUMAN | [view interactions] | High throughput | no | yes |
| ARL10_HUMAN | [view interactions] | High throughput | no | yes |
| ARFRP_HUMAN | [view interactions] | High throughput | no | yes |