AT2A1_HUMAN
Evidence for PS localization
Functions
Key regulator of striated muscle performance by acting as the major Ca(2+) ATPase responsible for the reuptake of cytosolic Ca(2+) into the sarcoplasmic reticulum. Catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol to the sarcoplasmic reticulum lumen . Contributes to calcium sequestration involved in muscular excitation/contraction (PubMed). [View more on UniProt]
Protein features
Binary interactions with known binding regions
To display all evidence describing the interaction with a partner, click on the protein name left to the bars.
Network
Isoforms
Disease-causing germline mutations
No data found.
Linear motifs
No annotated instance was found. To search for linear motifs, use the ELM prediction server.
Fingerprint
Molecular function
| Term | Name | % | Distance from the top of the tree | Annotated in AT2A1_HUMAN |
|---|---|---|---|---|
| GO:0046872 | metal ion binding | 25.2525 | 4 | yes |
| GO:0017076 | purine nucleotide binding | 19.1919 | 4 | yes |
| GO:0032555 | purine ribonucleotide binding | 19.1919 | 4 | yes |
| GO:0035639 | purine ribonucleoside triphosphate binding | 18.1818 | 4 | yes |
| GO:0030554 | adenyl nucleotide binding | 13.1313 | 5 | yes |
| GO:0032559 | adenyl ribonucleotide binding | 13.1313 | 5 | yes |
| GO:0005524 | ATP binding | 12.1212 | 5 | yes |
| GO:0042803 | protein homodimerization activity | 11.1111 | 4 | yes |
| GO:0008324 | cation transmembrane transporter activity | 9.0909 | 4 | yes |
| GO:0015399 | primary active transmembrane transporter activity | 9.0909 | 4 | yes |
| GO:0022890 | inorganic cation transmembrane transporter activity | 9.0909 | 4 | yes |
| GO:0005509 | calcium ion binding | 7.0707 | 5 | yes |
| GO:0022853 | active ion transmembrane transporter activity | 7.0707 | 4 | yes |
| GO:0046873 | metal ion transmembrane transporter activity | 7.0707 | 5 | yes |
| GO:0015085 | calcium ion transmembrane transporter activity | 5.0505 | 6 | yes |
| GO:0005388 | P-type calcium transporter activity | 4.0404 | 4 | yes |
| GO:0015662 | P-type ion transporter activity | 4.0404 | 4 | yes |
Biological process
| Term | Name | % | Distance from top the of the tree | Annotated in AT2A1_HUMAN |
|---|---|---|---|---|
| GO:0048522 | positive regulation of cellular process | 46.4646 | 4 | yes |
| GO:0071702 | organic substance transport | 39.3939 | 4 | no |
| GO:0010646 | regulation of cell communication | 35.3535 | 4 | no |
| GO:0008104 | protein localization | 34.3434 | 4 | no |
| GO:0060255 | regulation of macromolecule metabolic process | 34.3434 | 4 | no |
| GO:0031323 | regulation of cellular metabolic process | 33.3333 | 4 | no |
| GO:0048523 | negative regulation of cellular process | 33.3333 | 4 | no |
| GO:0051049 | regulation of transport | 31.3131 | 4 | yes |
| GO:0006996 | organelle organization | 30.3030 | 4 | yes |
| GO:0071705 | nitrogen compound transport | 30.3030 | 4 | no |
| GO:0080090 | regulation of primary metabolic process | 30.3030 | 4 | no |
| GO:0009893 | positive regulation of metabolic process | 28.2828 | 4 | no |
| GO:0009966 | regulation of signal transduction | 28.2828 | 4 | no |
| GO:0060341 | regulation of cellular localization | 27.2727 | 4 | yes |
| GO:0051171 | regulation of nitrogen compound metabolic process | 27.2727 | 4 | no |
| GO:0015031 | protein transport | 26.2626 | 4 | no |
| GO:0009892 | negative regulation of metabolic process | 24.2424 | 4 | no |
| GO:0032880 | regulation of protein localization | 24.2424 | 5 | no |
| GO:0010468 | regulation of gene expression | 22.2222 | 5 | no |
| GO:0010604 | positive regulation of macromolecule metabolic process | 22.2222 | 5 | no |
| GO:0051246 | regulation of protein metabolic process | 22.2222 | 5 | no |
| GO:0051050 | positive regulation of transport | 21.2121 | 4 | yes |
| GO:0016192 | vesicle-mediated transport | 21.2121 | 4 | no |
| GO:0051128 | regulation of cellular component organization | 21.2121 | 4 | no |
| GO:0010605 | negative regulation of macromolecule metabolic process | 21.2121 | 5 | no |
| GO:1902531 | regulation of intracellular signal transduction | 21.2121 | 5 | no |
| GO:0022607 | cellular component assembly | 20.2020 | 4 | no |
| GO:0023056 | positive regulation of signaling | 20.2020 | 4 | no |
| GO:0031325 | positive regulation of cellular metabolic process | 20.2020 | 5 | no |
| GO:0048878 | chemical homeostasis | 17.1717 | 4 | yes |
| GO:0006811 | ion transport | 16.1616 | 4 | yes |
| GO:0051240 | positive regulation of multicellular organismal process | 15.1515 | 4 | yes |
| GO:0050801 | ion homeostasis | 14.1414 | 5 | yes |
| GO:0055080 | cation homeostasis | 14.1414 | 6 | yes |
| GO:0098771 | inorganic ion homeostasis | 14.1414 | 6 | yes |
| GO:0006873 | cellular ion homeostasis | 13.1313 | 4 | yes |
| GO:0030003 | cellular cation homeostasis | 13.1313 | 5 | yes |
| GO:0043269 | regulation of ion transport | 12.1212 | 5 | yes |
| GO:0055065 | metal ion homeostasis | 12.1212 | 7 | yes |
| GO:0006875 | cellular metal ion homeostasis | 11.1111 | 6 | yes |
| GO:0032386 | regulation of intracellular transport | 11.1111 | 5 | yes |
| GO:0051241 | negative regulation of multicellular organismal process | 11.1111 | 4 | yes |
| GO:0006874 | cellular calcium ion homeostasis | 10.1010 | 7 | yes |
| GO:0055074 | calcium ion homeostasis | 10.1010 | 8 | yes |
| GO:0072503 | cellular divalent inorganic cation homeostasis | 10.1010 | 6 | yes |
| GO:0072507 | divalent inorganic cation homeostasis | 10.1010 | 7 | yes |
| GO:0006812 | cation transport | 9.0909 | 5 | yes |
| GO:0010959 | regulation of metal ion transport | 9.0909 | 6 | yes |
| GO:0030001 | metal ion transport | 9.0909 | 6 | yes |
| GO:0034762 | regulation of transmembrane transport | 9.0909 | 4 | yes |
| GO:0098660 | inorganic ion transmembrane transport | 9.0909 | 4 | yes |
| GO:0034765 | regulation of ion transmembrane transport | 8.0808 | 5 | yes |
| GO:0034976 | response to endoplasmic reticulum stress | 8.0808 | 4 | yes |
| GO:0098655 | cation transmembrane transport | 8.0808 | 4 | yes |
| GO:0098662 | inorganic cation transmembrane transport | 8.0808 | 5 | yes |
| GO:1904062 | regulation of cation transmembrane transport | 8.0808 | 6 | yes |
| GO:0043270 | positive regulation of ion transport | 7.0707 | 5 | yes |
| GO:0006816 | calcium ion transport | 6.0606 | 7 | yes |
| GO:0022898 | regulation of transmembrane transporter activity | 6.0606 | 4 | yes |
| GO:0032388 | positive regulation of intracellular transport | 6.0606 | 5 | yes |
| GO:0032412 | regulation of ion transmembrane transporter activity | 6.0606 | 5 | yes |
| GO:0044057 | regulation of system process | 6.0606 | 4 | yes |
| GO:0070588 | calcium ion transmembrane transport | 6.0606 | 6 | yes |
| GO:0032469 | endoplasmic reticulum calcium ion homeostasis | 5.0505 | 8 | yes |
| GO:0032970 | regulation of actin filament-based process | 5.0505 | 4 | yes |
| GO:0097193 | intrinsic apoptotic signaling pathway | 5.0505 | 4 | yes |
| GO:1903522 | regulation of blood circulation | 5.0505 | 5 | yes |
| GO:0008016 | regulation of heart contraction | 4.0404 | 6 | yes |
| GO:0034764 | positive regulation of transmembrane transport | 4.0404 | 5 | yes |
| GO:0090257 | regulation of muscle system process | 4.0404 | 5 | yes |
| GO:1903779 | regulation of cardiac conduction | 4.0404 | 4 | yes |
| GO:0006937 | regulation of muscle contraction | 3.0303 | 6 | yes |
| GO:0034767 | positive regulation of ion transmembrane transport | 3.0303 | 6 | yes |
| GO:0051924 | regulation of calcium ion transport | 3.0303 | 7 | yes |
| GO:0051928 | positive regulation of calcium ion transport | 3.0303 | 6 | yes |
| GO:0006942 | regulation of striated muscle contraction | 2.0202 | 7 | yes |
| GO:0007005 | mitochondrion organization | 2.0202 | 5 | yes |
| GO:0008637 | apoptotic mitochondrial changes | 2.0202 | 6 | yes |
| GO:0032411 | positive regulation of transporter activity | 2.0202 | 4 | yes |
| GO:0032470 | positive regulation of endoplasmic reticulum calcium ion concentration | 2.0202 | 9 | yes |
| GO:0055117 | regulation of cardiac muscle contraction | 2.0202 | 7 | yes |
| GO:0070059 | intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress | 2.0202 | 5 | yes |
| GO:0070296 | sarcoplasmic reticulum calcium ion transport | 2.0202 | 8 | yes |
| GO:0090075 | relaxation of muscle | 2.0202 | 4 | yes |
| GO:1904064 | positive regulation of cation transmembrane transport | 2.0202 | 7 | yes |
| GO:1990036 | calcium ion import into sarcoplasmic reticulum | 2.0202 | 4 | yes |
Disease
| Term | Name | % | Distance from top the of the tree | Annotated in AT2A1_HUMAN |
|---|---|---|---|---|
| DOID:331 | central nervous system disease | 6.0606 | 3 | no |
| DOID:1289 | neurodegenerative disease | 5.0505 | 4 | no |
| DOID:10595 | Charcot-Marie-Tooth disease | 2.0202 | 6 | no |
| DOID:440 | neuromuscular disease | 2.0202 | 5 | no |
| DOID:574 | peripheral nervous system disease | 2.0202 | 3 | no |
| DOID:870 | neuropathy | 2.0202 | 4 | no |
| DOID:0050155 | sensory system disease | 2.0202 | 3 | no |
| DOID:0050563 | nonsyndromic deafness | 2.0202 | 5 | no |
| DOID:0050564 | autosomal dominant nonsyndromic deafness | 2.0202 | 6 | no |
| DOID:2742 | auditory system disease | 2.0202 | 4 | no |
| DOID:0050753 | cerebellar ataxia | 2.0202 | 6 | no |
| DOID:0050951 | hereditary ataxia | 2.0202 | 5 | no |
| DOID:1441 | autosomal dominant cerebellar ataxia | 2.0202 | 7 | no |
| DOID:12377 | spinal muscular atrophy | 2.0202 | 6 | no |
| DOID:231 | motor neuron disease | 2.0202 | 5 | no |
All partners
| Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
|---|---|---|---|---|
| PIEZ1_HUMAN | [view interactions] | Low throughput | no | no |
| SARCO_HUMAN | [view interactions] | Low throughput | no | no |
| PPLA_HUMAN | [view interactions] | Low throughput | no | no |
| GPAT4_HUMAN | [view interactions] | High throughput | no | yes |
| ASTRA_HUMAN | [view interactions] | High throughput | no | no |
| HACD3_HUMAN | [view interactions] | High throughput | no | yes |
| HLAA_HUMAN | [view interactions] | High throughput | no | no |
| HLAC_HUMAN | [view interactions] | High throughput | no | no |
| HM13_HUMAN | [view interactions] | High throughput | no | yes |
| HMDH_HUMAN | [view interactions] | High throughput | no | yes |
| HMOX2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MPRI_HUMAN | [view interactions] | High throughput | no | yes |
| IKIP_HUMAN | [view interactions] | High throughput | no | no |
| INF2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| IPO5_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ITA6_HUMAN | [view interactions] | High throughput | no | yes |
| ITB1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ITPR1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ITPR2_HUMAN | [view interactions] | High throughput | no | yes |
| JPH1_HUMAN | [view interactions] | High throughput | no | no |
| KTN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LBR_HUMAN | [view interactions] | High throughput | no | yes |
| LMAN1_HUMAN | [view interactions] | High throughput | no | yes |
| LMF2_HUMAN | [view interactions] | High throughput | no | yes |
| LCAP_HUMAN | [view interactions] | High throughput | no | yes |
| LNP_HUMAN | [view interactions] | High throughput | no | yes |
| PCAT1_HUMAN | [view interactions] | High throughput | no | yes |
| LRIG2_HUMAN | [view interactions] | High throughput | no | yes |
| LRC59_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MET14_HUMAN | [view interactions] | High throughput | no | yes |
| LRC8A_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| SH3L1_HUMAN | [view interactions] | High throughput | no | yes |
| MACOI_HUMAN | [view interactions] | High throughput | no | no |
| COX15_HUMAN | [view interactions] | High throughput | no | yes |
| MAGT1_HUMAN | [view interactions] | High throughput | no | yes |
| ODO2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MBOA2_HUMAN | [view interactions] | High throughput | no | yes |
| ODPA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MBOA7_HUMAN | [view interactions] | High throughput | no | no |
| MDN1_HUMAN | [view interactions] | High throughput | no | no |
| PAK6_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TGO1_HUMAN | [view interactions] | High throughput | no | yes |
| HSPB8_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| EMC5_HUMAN | [view interactions] | High throughput | no | yes |
| JUN_HUMAN | [view interactions] | High throughput | no | yes |
| MSPD2_HUMAN | [view interactions] | High throughput | no | yes |
| ITM2B_HUMAN | [view interactions] | High throughput | no | yes |
| LYRIC_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CCR8_HUMAN | [view interactions] | High throughput | no | no |
| MXRA7_HUMAN | [view interactions] | High throughput | no | yes |
| TNR1B_HUMAN | [view interactions] | High throughput | no | no |
| NDC1_HUMAN | [view interactions] | High throughput | no | yes |
| CUL3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NOC2L_HUMAN | [view interactions] | High throughput | no | yes |
| TIFAB_HUMAN | [view interactions] | High throughput | no | no |
| NOTC2_HUMAN | [view interactions] | High throughput | no | yes |
| DP13A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NSDHL_HUMAN | [view interactions] | High throughput | no | yes |
| RN167_HUMAN | [view interactions] | High throughput | no | yes |
| NU155_HUMAN | [view interactions] | High throughput | no | yes |
| TULP3_HUMAN | [view interactions] | High throughput | no | yes |
| PO210_HUMAN | [view interactions] | High throughput | no | yes |
| NUP35_HUMAN | [view interactions] | High throughput | no | yes |
| OSBL2_HUMAN | [view interactions] | High throughput | no | yes |
| PCKGC_HUMAN | [view interactions] | High throughput | no | no |
| OSBL8_HUMAN | [view interactions] | High throughput | no | yes |
| CFTR_HUMAN | [view interactions] | High throughput | no | no |
| PDE3B_HUMAN | [view interactions] | High throughput | no | no |
| WWOX_HUMAN | [view interactions] | High throughput | no | yes |
| PDZD8_HUMAN | [view interactions] | High throughput | no | yes |
| LGR4_HUMAN | [view interactions] | High throughput | no | yes |
| PGRC1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ROGDI_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PGRC2_HUMAN | [view interactions] | High throughput | no | yes |
| GNT2A_HUMAN | [view interactions] | High throughput | no | yes |
| PMYT1_HUMAN | [view interactions] | High throughput | no | no |
| SETB1_HUMAN | [view interactions] | High throughput | no | yes |
| PLD3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ATOH1_HUMAN | [view interactions] | High throughput | no | no |
| PLXB2_HUMAN | [view interactions] | High throughput | no | yes |
| LRCC1_HUMAN | [view interactions] | High throughput | no | yes |
| NCPR_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| VNN2_HUMAN | [view interactions] | High throughput | no | no |
| PRAF2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TLE3_HUMAN | [view interactions] | High throughput | no | yes |
| PREB_HUMAN | [view interactions] | High throughput | no | yes |
| H4_HUMAN | [view interactions] | High throughput | no | yes |
| KPCD_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HMGB1_HUMAN | [view interactions] | High throughput | no | yes |
| PTN1_HUMAN | [view interactions] | High throughput | no | yes |
| GRTP1_HUMAN | [view interactions] | High throughput | no | yes |
| PTN2_HUMAN | [view interactions] | High throughput | no | yes |
| FACD2_HUMAN | [view interactions] | High throughput | no | no |
| RAB23_HUMAN | [view interactions] | High throughput | no | yes |
| RNF31_HUMAN | [view interactions] | High throughput | no | yes |
| RAB3B_HUMAN | [view interactions] | High throughput | no | no |
| REQU_HUMAN | [view interactions] | High throughput | no | yes |
| RB3GP_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ATX1_HUMAN | [view interactions] | High throughput | no | yes |
| RBGPR_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DUS7_HUMAN | [view interactions] | High throughput | no | yes |
| RAB7A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PTPRM_HUMAN | [view interactions] | High throughput | no | yes |
| RABL3_HUMAN | [view interactions] | High throughput | no | yes |
| TPTE_HUMAN | [view interactions] | High throughput | no | no |
| REEP5_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| BRD7_HUMAN | [view interactions] | High throughput | no | yes |
| RETR1_HUMAN | [view interactions] | High throughput | no | no |
| AGO2_HUMAN | [view interactions] | High throughput | no | yes |
| RFT1_HUMAN | [view interactions] | High throughput | no | yes |
| CTRO_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RINT1_HUMAN | [view interactions] | High throughput | no | yes |
| ECT2_HUMAN | [view interactions] | High throughput | no | no |
| RPN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KIF14_HUMAN | [view interactions] | High throughput | no | no |
| RRBP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KI20A_HUMAN | [view interactions] | High throughput | no | yes |
| RTN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DDX58_HUMAN | [view interactions] | High throughput | no | yes |
| RTN3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DX39A_HUMAN | [view interactions] | High throughput | no | yes |
| RTN4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| VMP1_HUMAN | [view interactions] | High throughput | no | yes |
| SAR1A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PAGE4_HUMAN | [view interactions] | High throughput | no | no |
| SAR1B_HUMAN | [view interactions] | High throughput | no | yes |
| GOLM1_HUMAN | [view interactions] | High throughput | no | yes |
| SCRB1_HUMAN | [view interactions] | High throughput | no | no |
| COA1_HUMAN | [view interactions] | High throughput | no | yes |
| SCD5_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SGMR2_HUMAN | [view interactions] | High throughput | no | no |
| SCFD1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ENTP2_HUMAN | [view interactions] | High throughput | no | yes |
| SC16A_HUMAN | [view interactions] | High throughput | no | yes |
| PM34_HUMAN | [view interactions] | High throughput | no | yes |
| SC22B_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| PTPM1_HUMAN | [view interactions] | High throughput | no | yes |
| SC24A_HUMAN | [view interactions] | High throughput | no | no |
| GNL3L_HUMAN | [view interactions] | High throughput | no | yes |
| SC24B_HUMAN | [view interactions] | High throughput | no | yes |
| NAT14_HUMAN | [view interactions] | High throughput | no | no |
| SC61B_HUMAN | [view interactions] | High throughput | no | yes |
| AG10A_HUMAN | [view interactions] | High throughput | no | yes |
| SEC63_HUMAN | [view interactions] | High throughput | no | yes |
| GPHRA_HUMAN | [view interactions] | High throughput | no | no |
| SELS_HUMAN | [view interactions] | High throughput | no | yes |
| OPALI_HUMAN | [view interactions] | High throughput | no | yes |
| SENP2_HUMAN | [view interactions] | High throughput | no | yes |
| CC033_HUMAN | [view interactions] | High throughput | no | yes |
| SGPL1_HUMAN | [view interactions] | High throughput | no | yes |
| CANT1_HUMAN | [view interactions] | High throughput | no | yes |
| S12A2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PEX16_HUMAN | [view interactions] | High throughput | no | yes |
| S27A4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CKAP4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ZNT7_HUMAN | [view interactions] | High throughput | no | no |
| PXMP2_HUMAN | [view interactions] | High throughput | no | no |
| ACATN_HUMAN | [view interactions] | High throughput | no | yes |
| ABCD3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| B3A2_HUMAN | [view interactions] | High throughput | no | yes |
| ORC5_HUMAN | [view interactions] | High throughput | no | yes |
| S6A15_HUMAN | [view interactions] | High throughput | no | yes |
| ABCD1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| SL9A1_HUMAN | [view interactions] | High throughput | no | no |
| MAN1_HUMAN | [view interactions] | High throughput | no | yes |
| SLMAP_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HACD2_HUMAN | [view interactions] | High throughput | no | yes |
| SIM12_HUMAN | [view interactions] | High throughput | no | yes |
| K1C39_HUMAN | [view interactions] | High throughput | no | no |
| NSMA3_HUMAN | [view interactions] | High throughput | no | yes |
| MUL1_HUMAN | [view interactions] | High throughput | no | no |
| SNP29_HUMAN | [view interactions] | High throughput | no | yes |
| OSTC_HUMAN | [view interactions] | High throughput | no | no |
| SNP47_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| B4GN3_HUMAN | [view interactions] | High throughput | no | no |
| SNX19_HUMAN | [view interactions] | High throughput | no | yes |
| ENTP4_HUMAN | [view interactions] | High throughput | no | yes |
| SOAT1_HUMAN | [view interactions] | High throughput | no | no |
| F162A_HUMAN | [view interactions] | High throughput | no | yes |
| SPCS2_HUMAN | [view interactions] | High throughput | no | yes |
| GPAT3_HUMAN | [view interactions] | High throughput | no | yes |
| SRPRA_HUMAN | [view interactions] | High throughput | no | no |
| AT2A3_HUMAN | [view interactions] | High throughput | no | yes |
| SRPRB_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| PEX10_HUMAN | [view interactions] | High throughput | no | yes |
| SSRA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NSUN5_HUMAN | [view interactions] | High throughput | no | yes |
| STBD1_HUMAN | [view interactions] | High throughput | no | yes |
| CY1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| STIM1_HUMAN | [view interactions] | High throughput | no | yes |
| ABD12_HUMAN | [view interactions] | High throughput | no | no |
| STIM2_HUMAN | [view interactions] | High throughput | no | yes |
| ECHB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| STOM_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NB5R1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| STT3B_HUMAN | [view interactions] | High throughput | no | yes |
| SCMC1_HUMAN | [view interactions] | High throughput | no | no |
| STX18_HUMAN | [view interactions] | High throughput | no | yes |
| HS2ST_HUMAN | [view interactions] | High throughput | no | yes |
| STX5_HUMAN | [view interactions] | High throughput | no | yes |
| ABTB2_HUMAN | [view interactions] | High throughput | no | yes |
| SUN1_HUMAN | [view interactions] | High throughput | no | yes |
| QCR8_HUMAN | [view interactions] | High throughput | no | yes |
| SPT5H_HUMAN | [view interactions] | High throughput | no | yes |
| MECOM_HUMAN | [view interactions] | High throughput | no | yes |
| SYAP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FACR2_HUMAN | [view interactions] | High throughput | no | yes |
| SYNE2_HUMAN | [view interactions] | High throughput | no | no |
| VCAM1_HUMAN | [view interactions] | High throughput | no | no |
| TACC1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MICU1_HUMAN | [view interactions] | High throughput | no | yes |
| TAPT1_HUMAN | [view interactions] | High throughput | no | yes |
| NOMO1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TEX2_HUMAN | [view interactions] | High throughput | no | yes |
| DQA1_HUMAN | [view interactions] | High throughput | no | yes |
| TX264_HUMAN | [view interactions] | High throughput | no | no |
| GOLI4_HUMAN | [view interactions] | High throughput | no | yes |
| TFR1_HUMAN | [view interactions] | High throughput | no | yes |
| EXOG_HUMAN | [view interactions] | High throughput | no | yes |
| TM9S2_HUMAN | [view interactions] | High throughput | no | yes |
| LTMD1_HUMAN | [view interactions] | High throughput | no | no |
| TM9S3_HUMAN | [view interactions] | High throughput | no | yes |
| AT2A2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TMCO1_HUMAN | [view interactions] | High throughput | no | yes |
| CPT1A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TM109_HUMAN | [view interactions] | High throughput | no | yes |
| TV23C_HUMAN | [view interactions] | High throughput | no | no |
| T161A_HUMAN | [view interactions] | High throughput | no | yes |
| TM143_HUMAN | [view interactions] | High throughput | no | yes |
| TM199_HUMAN | [view interactions] | High throughput | no | yes |
| DD19B_HUMAN | [view interactions] | High throughput | no | yes |
| TM201_HUMAN | [view interactions] | High throughput | no | no |
| GLBL2_HUMAN | [view interactions] | High throughput | no | no |
| TM209_HUMAN | [view interactions] | High throughput | no | no |
| ATP9A_HUMAN | [view interactions] | High throughput | no | yes |
| TM214_HUMAN | [view interactions] | High throughput | no | no |
| PIGW_HUMAN | [view interactions] | High throughput | no | no |
| TM38B_HUMAN | [view interactions] | High throughput | no | yes |
| MITOS_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TM41B_HUMAN | [view interactions] | High throughput | no | yes |
| DGAT1_HUMAN | [view interactions] | High throughput | no | yes |
| LAP2A_HUMAN | [view interactions] | High throughput | no | yes |
| ARMX3_HUMAN | [view interactions] | High throughput | no | no |
| TMX1_HUMAN | [view interactions] | High throughput | no | no |
| RSH6A_HUMAN | [view interactions] | High throughput | no | no |
| TMX2_HUMAN | [view interactions] | High throughput | no | yes |
| T120B_HUMAN | [view interactions] | High throughput | no | yes |
| TMX3_HUMAN | [view interactions] | High throughput | no | yes |
| SPG7_HUMAN | [view interactions] | High throughput | no | no |
| TOIP1_HUMAN | [view interactions] | High throughput | no | yes |
| LPAR1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| TOIP2_HUMAN | [view interactions] | High throughput | no | no |
| QCR6_HUMAN | [view interactions] | High throughput | no | yes |
| TRI13_HUMAN | [view interactions] | High throughput | no | no |
| LHX3_HUMAN | [view interactions] | High throughput | no | no |
| TRPM7_HUMAN | [view interactions] | High throughput | no | no |
| NDUA3_HUMAN | [view interactions] | High throughput | no | yes |
| TYW1_HUMAN | [view interactions] | High throughput | no | yes |
| NTCP7_HUMAN | [view interactions] | High throughput | no | no |
| UBAC2_HUMAN | [view interactions] | High throughput | no | yes |
| ARL8B_HUMAN | [view interactions] | High throughput | no | yes |
| UB2J1_HUMAN | [view interactions] | High throughput | no | yes |
| TIM14_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| UBIA1_HUMAN | [view interactions] | High throughput | no | no |
| GPDM_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| UBXN4_HUMAN | [view interactions] | High throughput | no | yes |
| TLCD1_HUMAN | [view interactions] | High throughput | no | yes |
| UBXN8_HUMAN | [view interactions] | High throughput | no | yes |
| LEMD2_HUMAN | [view interactions] | High throughput | no | yes |
| UFL1_HUMAN | [view interactions] | High throughput | no | yes |
| EXT1_HUMAN | [view interactions] | High throughput | no | yes |
| CGT_HUMAN | [view interactions] | High throughput | no | no |
| CE024_HUMAN | [view interactions] | High throughput | no | yes |
| USE1_HUMAN | [view interactions] | High throughput | no | yes |
| TSN33_HUMAN | [view interactions] | High throughput | no | no |
| UBP33_HUMAN | [view interactions] | High throughput | no | yes |
| CLDN1_HUMAN | [view interactions] | High throughput | no | yes |
| UTP20_HUMAN | [view interactions] | High throughput | no | no |
| SIAT1_HUMAN | [view interactions] | High throughput | no | no |
| VAMP2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| NPTN_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| VAMP3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| DQB1_HUMAN | [view interactions] | High throughput | no | no |
| VANG1_HUMAN | [view interactions] | High throughput | no | no |
| MRAP2_HUMAN | [view interactions] | High throughput | no | no |
| VANG2_HUMAN | [view interactions] | High throughput | no | no |
| LATS1_HUMAN | [view interactions] | High throughput | no | yes |
| VAPA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CYTM_HUMAN | [view interactions] | High throughput | no | no |
| VAPB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SPRTN_HUMAN | [view interactions] | High throughput | no | yes |
| VEZA_HUMAN | [view interactions] | High throughput | no | yes |
| UBP11_HUMAN | [view interactions] | High throughput | no | yes |
| VKORL_HUMAN | [view interactions] | High throughput | no | yes |
| ITPR3_HUMAN | [view interactions] | High throughput | no | yes |
| VPS35_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| BASI_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| VRK2_HUMAN | [view interactions] | High throughput | no | no |
| CALX_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| WDR41_HUMAN | [view interactions] | High throughput | no | yes |
| KCRS_HUMAN | [view interactions] | High throughput | no | no |
| WFS1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| K2C4_HUMAN | [view interactions] | High throughput | no | no |
| WLS_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| MYH1_HUMAN | [view interactions] | High throughput | no | no |
| XPO1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MYPN_HUMAN | [view interactions] | High throughput | no | no |
| YIF1A_HUMAN | [view interactions] | High throughput | no | yes |
| MYOME_HUMAN | [view interactions] | High throughput | no | no |
| YKT6_HUMAN | [view interactions] | High throughput | no | yes |
| TNNI2_HUMAN | [view interactions] | High throughput | no | no |
| ZCCHV_HUMAN | [view interactions] | High throughput | no | yes |
| PPR3A_HUMAN | [view interactions] | High throughput | no | no |
| ZFY27_HUMAN | [view interactions] | High throughput | no | yes |
| AGR2_HUMAN | [view interactions] | High throughput | no | no |
| FACE1_HUMAN | [view interactions] | High throughput | no | yes |
| MRP1_HUMAN | [view interactions] | High throughput | no | no |
| ZW10_HUMAN | [view interactions] | High throughput | no | yes |
| GCP60_HUMAN | [view interactions] | High throughput | no | yes |
| APBB1_HUMAN | [view interactions] | High throughput | no | yes |
| ACBD5_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CF047_HUMAN | [view interactions] | High throughput | no | no |
| ACSL3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CLMN_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ADCY9_HUMAN | [view interactions] | High throughput | no | yes |
| DDX24_HUMAN | [view interactions] | High throughput | no | yes |
| PLCA_HUMAN | [view interactions] | High throughput | no | yes |
| DEP1B_HUMAN | [view interactions] | High throughput | no | yes |
| PLCC_HUMAN | [view interactions] | High throughput | no | no |
| FLVC1_HUMAN | [view interactions] | High throughput | no | yes |
| AL3A2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GRAM4_HUMAN | [view interactions] | High throughput | no | no |
| ALG9_HUMAN | [view interactions] | High throughput | no | yes |
| ITAV_HUMAN | [view interactions] | High throughput | no | yes |
| ANKL2_HUMAN | [view interactions] | High throughput | no | yes |
| LSG1_HUMAN | [view interactions] | High throughput | no | yes |
| ANO10_HUMAN | [view interactions] | High throughput | no | yes |
| REEP2_HUMAN | [view interactions] | High throughput | no | yes |
| ANO6_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RER1_HUMAN | [view interactions] | High throughput | no | yes |
| ANO8_HUMAN | [view interactions] | High throughput | no | no |
| RS27L_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| AP2A1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| S38A2_HUMAN | [view interactions] | High throughput | no | yes |
| APOL2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SPTC1_HUMAN | [view interactions] | High throughput | no | yes |
| A4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SPTC2_HUMAN | [view interactions] | High throughput | no | no |
| ARF6_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TBL2_HUMAN | [view interactions] | High throughput | no | no |
| ARFG2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| UBR4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ARFG3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| USP9X_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RHG01_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PRAF3_HUMAN | [view interactions] | High throughput | no | yes |
| ATLA1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ATLA2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AT131_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| AT2B1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AT2B4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RENR_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AUP1_HUMAN | [view interactions] | High throughput | no | yes |
| BAP31_HUMAN | [view interactions] | High throughput | no | yes |
| BET1_HUMAN | [view interactions] | High throughput | no | no |
| SEC20_HUMAN | [view interactions] | High throughput | no | yes |
| BRI3B_HUMAN | [view interactions] | High throughput | no | yes |
| RUSF1_HUMAN | [view interactions] | High throughput | no | yes |
| C2C2L_HUMAN | [view interactions] | High throughput | no | yes |
| CAMLG_HUMAN | [view interactions] | High throughput | no | yes |
| CCD47_HUMAN | [view interactions] | High throughput | no | yes |
| CCPG1_HUMAN | [view interactions] | High throughput | no | yes |
| CK5P3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CDKAL_HUMAN | [view interactions] | High throughput | no | no |
| CERS1_HUMAN | [view interactions] | High throughput | no | yes |
| CERS2_HUMAN | [view interactions] | High throughput | no | no |
| CHMP7_HUMAN | [view interactions] | High throughput | no | yes |
| CHP1_HUMAN | [view interactions] | High throughput | no | yes |
| CISD2_HUMAN | [view interactions] | High throughput | no | yes |
| CLCC1_HUMAN | [view interactions] | High throughput | no | yes |
| CLCN7_HUMAN | [view interactions] | High throughput | no | yes |
| CLGN_HUMAN | [view interactions] | High throughput | no | no |
| CLPT1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CLP1L_HUMAN | [view interactions] | High throughput | no | yes |
| COPA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CBPD_HUMAN | [view interactions] | High throughput | no | yes |
| CYB5_HUMAN | [view interactions] | High throughput | no | no |
| CYB5B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NB5R3_HUMAN | [view interactions] | High throughput | no | yes |
| CP51A_HUMAN | [view interactions] | High throughput | no | no |
| DDHD2_HUMAN | [view interactions] | High throughput | no | yes |
| DDRGK_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DHC24_HUMAN | [view interactions] | High throughput | no | yes |
| DHRS7_HUMAN | [view interactions] | High throughput | no | yes |
| DNJC1_HUMAN | [view interactions] | High throughput | no | yes |
| DJC16_HUMAN | [view interactions] | High throughput | no | no |
| D19L1_HUMAN | [view interactions] | High throughput | no | yes |
| DSC2_HUMAN | [view interactions] | High throughput | no | no |
| EI24_HUMAN | [view interactions] | High throughput | no | yes |
| E2AK3_HUMAN | [view interactions] | High throughput | no | yes |
| ELOV2_HUMAN | [view interactions] | High throughput | no | no |
| EMC2_HUMAN | [view interactions] | High throughput | no | yes |
| EMC7_HUMAN | [view interactions] | High throughput | no | yes |
| EMC8_HUMAN | [view interactions] | High throughput | no | no |
| EMD_HUMAN | [view interactions] | High throughput | no | yes |
| ESYT1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ESYT2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FADS2_HUMAN | [view interactions] | High throughput | no | yes |
| FAF2_HUMAN | [view interactions] | High throughput | no | yes |
| F1142_HUMAN | [view interactions] | High throughput | no | yes |
| FDFT_HUMAN | [view interactions] | High throughput | no | yes |
| FKBP8_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FND3A_HUMAN | [view interactions] | High throughput | no | yes |
| FRAS1_HUMAN | [view interactions] | High throughput | no | yes |
| GBA2_HUMAN | [view interactions] | High throughput | no | yes |
| VKGC_HUMAN | [view interactions] | High throughput | no | yes |
| GGT7_HUMAN | [view interactions] | High throughput | no | yes |
| CXA1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GORS2_HUMAN | [view interactions] | High throughput | no | yes |
| GOSR2_HUMAN | [view interactions] | High throughput | no | yes |
| TNNT3_HUMAN | [view interactions] | Computational | no | no |
| RORA_HUMAN | [view interactions] | Computational | no | yes |
| CASQ1_HUMAN | [view interactions] | Computational | no | yes |
| SRCH_HUMAN | [view interactions] | Computational | no | no |
| MLRS_HUMAN | [view interactions] | Computational | no | no |
| TNNC2_HUMAN | [view interactions] | Computational | no | no |
| MYOZ1_HUMAN | [view interactions] | Computational | no | no |
| NOTC4_HUMAN | [view interactions] | Computational | no | no |
| RYR1_HUMAN | [view interactions] | Computational | no | no |
| NOTC3_HUMAN | [view interactions] | Computational | no | yes |
| SRCA_HUMAN | [view interactions] | Computational | no | no |
| KAT5_HUMAN | [view interactions] | Computational | no | yes |