Features Interactions Isoform Disease Linear motifs Fingerprint Network All partners

ABCD1_HUMAN

Evidence for PS localization

GO
G2C
SynGO
SynaptomeDB

Functions

Plays a role in the transport of free very-long-chain fatty acids (VLCFAs) as well as their CoA-esters across the peroxisomal membrane by acting as an ATP-specific binding subunit releasing ADP after ATP hydrolysis (PubMed, PubMed, PubMed, PubMed). Thus, plays a role in regulation of VLCFAs and energy metabolism namely, in the degradation and biosynthesis of fatty acids by beta-oxidation, mitochondrial function and microsomal fatty acid elongation (PubMed). Involved in several processes; namely, controls the active myelination phase by negatively regulating the microsomal fatty acid elongation activity and may also play a role in axon and myelin maintenance. Controls also the cellular response to oxidative stress by regulating mitochondrial function like, mitochondrial oxidative phosphorylation and depolarization. And finally controls the inflammatory response by positively regulating peroxisomal beta-oxidation of VLCFAs . [View more on UniProt]

Protein features

Binary interactions with known binding regions

To display all evidence describing the interaction with a partner, click on the protein name left to the bars.

Network

Download full PS network for entry.

Isoforms

Disease-causing germline mutations

Position Amino acid Mutation Disease Overlap with binding region
98 Ser Leu Adrenoleukodystrophy(ALD) -
104 Arg Cys Adrenoleukodystrophy(ALD) -
104 Arg His Adrenoleukodystrophy(ALD) -
105 Thr Ile Adrenoleukodystrophy(ALD) -
107 Leu Pro Adrenoleukodystrophy(ALD) -
108 Ser Trp Adrenoleukodystrophy(ALD) -
116 Gly Arg Adrenoleukodystrophy(ALD) -
141 Ala Thr Adrenoleukodystrophy(ALD) -
148 Asn Ser Adrenoleukodystrophy(ALD) -
149 Ser Asn Adrenoleukodystrophy(ALD) -
152 Arg Cys Adrenoleukodystrophy(ALD) -
152 Arg Pro Adrenoleukodystrophy(ALD) -
163 Arg His Adrenoleukodystrophy(ALD) -
174 Tyr Asp Adrenoleukodystrophy(ALD) -
174 Tyr Ser Adrenoleukodystrophy(ALD) -
178 Gln Glu Adrenoleukodystrophy(ALD) -
181 Tyr Cys Adrenoleukodystrophy(ALD) -
182 Arg Pro Adrenoleukodystrophy(ALD) -
194 Asp His Adrenoleukodystrophy(ALD) -
200 Asp Val Adrenoleukodystrophy(ALD) -
211 Leu Pro Adrenoleukodystrophy(ALD) -
220 Leu Pro Adrenoleukodystrophy(ALD) -
221 Asp Gly Adrenoleukodystrophy(ALD) -
254 Thr Met Adrenoleukodystrophy(ALD) -
254 Thr Pro Adrenoleukodystrophy(ALD) -
263 Pro Leu Adrenoleukodystrophy(ALD) -
266 Gly Arg Adrenoleukodystrophy(ALD) -
276 Lys Glu Adrenoleukodystrophy(ALD) -
277 Gly Arg Adrenoleukodystrophy(ALD) -
277 Gly Trp Adrenoleukodystrophy(ALD) -
291 Glu Asp Adrenoleukodystrophy(ALD) -
291 Glu Lys Adrenoleukodystrophy(ALD) -
294 Ala Thr Adrenoleukodystrophy(ALD) -
342 Ser Pro Adrenoleukodystrophy(ALD) -
389 Arg Gly Adrenoleukodystrophy(ALD) -
389 Arg His Adrenoleukodystrophy(ALD) -
401 Arg Gln Adrenoleukodystrophy(ALD) -
418 Arg Trp Adrenoleukodystrophy(ALD) -
484 Pro Arg Adrenoleukodystrophy(ALD) -
507 Gly Val Adrenoleukodystrophy(ALD) -
512 Gly Ser Adrenoleukodystrophy(ALD) -
515 Ser Phe Adrenoleukodystrophy(ALD) -
518 Arg Gln Adrenoleukodystrophy(ALD) -
518 Arg Trp Adrenoleukodystrophy(ALD) -
522 Gly Trp Adrenoleukodystrophy(ALD) -
534 Pro Leu Adrenoleukodystrophy(ALD) -
560 Pro Leu Adrenoleukodystrophy(ALD) -
560 Pro Arg Adrenoleukodystrophy(ALD) -
566 Met Lys Adrenoleukodystrophy(ALD) -
591 Arg Gln Adrenoleukodystrophy(ALD) -
606 Ser Leu Adrenoleukodystrophy(ALD) -
606 Ser Pro Adrenoleukodystrophy(ALD) -
609 Glu Gly Adrenoleukodystrophy(ALD) -
609 Glu Lys Adrenoleukodystrophy(ALD) -
617 Arg Cys Adrenoleukodystrophy(ALD) -
617 Arg Gly Adrenoleukodystrophy(ALD) -
617 Arg His Adrenoleukodystrophy(ALD) -
626 Ala Thr Adrenoleukodystrophy(ALD) -
629 Asp His Adrenoleukodystrophy(ALD) -
660 Arg Trp Adrenoleukodystrophy(ALD) -
679 Trp Arg Adrenoleukodystrophy(ALD) -
90 Glu Lys Adrenoleukodystrophy(ALD) -
103 Ser Arg Adrenoleukodystrophy(ALD) -
105 Thr Pro Adrenoleukodystrophy(ALD) -
108 Ser Leu Adrenoleukodystrophy(ALD) -
113 Arg Cys Adrenoleukodystrophy(ALD) -
143 Pro Ser Adrenoleukodystrophy(ALD) -
152 Arg Leu Adrenoleukodystrophy(ALD) -
152 Arg Ser Adrenoleukodystrophy(ALD) -
161 Ser Pro Adrenoleukodystrophy(ALD) -
163 Arg Pro Adrenoleukodystrophy(ALD) -
174 Tyr Cys Adrenoleukodystrophy(ALD) -
189 Arg Trp Adrenoleukodystrophy(ALD) -
190 Leu Pro Adrenoleukodystrophy(ALD) -
198 Thr Lys Adrenoleukodystrophy(ALD) -
200 Asp Asn Adrenoleukodystrophy(ALD) -
213 Ser Cys Adrenoleukodystrophy(ALD) -
214 Asn Asp Adrenoleukodystrophy(ALD) -
218 Pro Thr Adrenoleukodystrophy(ALD) -
229 Leu Pro Adrenoleukodystrophy(ALD) -
271 Glu Lys Adrenoleukodystrophy(ALD) -
285 Arg Pro Adrenoleukodystrophy(ALD) -
296 Tyr Cys Adrenoleukodystrophy(ALD) -
298 Gly Asp Adrenoleukodystrophy(ALD) -
302 Glu Lys Adrenoleukodystrophy(ALD) -
322 Leu Pro Adrenoleukodystrophy(ALD) -
336 Lys Met Adrenoleukodystrophy(ALD) -
401 Arg Trp Adrenoleukodystrophy(ALD) -
529 Gly Ser Adrenoleukodystrophy(ALD) -
540 Phe Ser Adrenoleukodystrophy(ALD) -
543 Pro Leu Adrenoleukodystrophy(ALD) -
544 Gln Arg Adrenoleukodystrophy(ALD) -
552 Ser Pro Adrenoleukodystrophy(ALD) -
554 Arg His Adrenoleukodystrophy(ALD) -
591 Arg Trp Adrenoleukodystrophy(ALD) -
616 Ala Val Adrenoleukodystrophy(ALD) -
630 Glu Gly Adrenoleukodystrophy(ALD) -
631 Cys Tyr Adrenoleukodystrophy(ALD) -
633 Ser Arg Adrenoleukodystrophy(ALD) -
636 Ser Ile Adrenoleukodystrophy(ALD) -
638 Asp Tyr Adrenoleukodystrophy(ALD) -
646 Ala Pro Adrenoleukodystrophy(ALD) -
654 Leu Pro Adrenoleukodystrophy(ALD) -
667 His Asp Adrenoleukodystrophy(ALD) -
668 Thr Ile Adrenoleukodystrophy(ALD) -
693 Thr Met Adrenoleukodystrophy(ALD) -
99 Ala Asp Adrenoleukodystrophy(ALD) -
113 Arg Pro Adrenoleukodystrophy(ALD) -
217 Lys Glu Adrenoleukodystrophy(ALD) -
224 Val Glu Adrenoleukodystrophy(ALD) -
274 Arg Trp Adrenoleukodystrophy(ALD) -
280 Arg Cys Adrenoleukodystrophy(ALD) -
339 Trp Arg Adrenoleukodystrophy(ALD) -
343 Gly Asp Adrenoleukodystrophy(ALD) -
556 Gln Arg Adrenoleukodystrophy(ALD) -
560 Pro Ser Adrenoleukodystrophy(ALD) -
591 Arg Pro Adrenoleukodystrophy(ALD) -
608 Gly Asp Adrenoleukodystrophy(ALD) -
626 Ala Asp Adrenoleukodystrophy(ALD) -
632 Thr Ile Adrenoleukodystrophy(ALD) -
633 Ser Ile Adrenoleukodystrophy(ALD) -
635 Val Met Adrenoleukodystrophy(ALD) -
660 Arg Pro Adrenoleukodystrophy(ALD) -
88 Cys Trp Adrenoleukodystrophy(ALD) -
343 Gly Ser Adrenoleukodystrophy(ALD) -
503 Leu Pro Adrenoleukodystrophy(ALD) -
514 Ser Arg Adrenoleukodystrophy(ALD) -
198 Thr Arg Adrenoleukodystrophy(ALD) -
266 Gly Glu Adrenoleukodystrophy(ALD) -
523 Leu Phe Adrenoleukodystrophy(ALD) -
540 Phe Cys Adrenoleukodystrophy(ALD) -
632 Thr Pro Adrenoleukodystrophy(ALD) -
640 Glu Lys Adrenoleukodystrophy(ALD) -
677 Gly Asp Adrenoleukodystrophy(ALD) -
516 Leu Pro Adrenoleukodystrophy(ALD) -
660 Arg Gln Adrenoleukodystrophy(ALD) -
95 Ala Asp Adrenoleukodystrophy(ALD) -
316 Gln Pro Adrenoleukodystrophy(ALD) -

Linear motifs

No annotated instance was found. To search for linear motifs, use the ELM prediction server.

Fingerprint

Molecular function

Term Name % Distance from the top of the tree Annotated in ABCD1_HUMAN
GO:0017076 purine nucleotide binding 37.9310 4 yes
GO:0032555 purine ribonucleotide binding 37.9310 4 yes
GO:0035639 purine ribonucleoside triphosphate binding 34.4828 4 yes
GO:0015399 primary active transmembrane transporter activity 27.5862 4 yes
GO:0030554 adenyl nucleotide binding 27.5862 5 yes
GO:0032559 adenyl ribonucleotide binding 27.5862 5 yes
GO:0005524 ATP binding 24.1379 5 yes
GO:0016462 pyrophosphatase activity 24.1379 5 yes
GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 24.1379 4 yes
GO:0017111 ribonucleoside triphosphate phosphatase activity 24.1379 6 yes
GO:0042803 protein homodimerization activity 24.1379 4 yes
GO:0016887 ATP hydrolysis activity 13.7931 7 yes
GO:0016289 CoA hydrolase activity 10.3448 5 yes
GO:0016790 thiolester hydrolase activity 10.3448 4 yes
GO:0046982 protein heterodimerization activity 10.3448 4 yes
GO:0047617 acyl-CoA hydrolase activity 10.3448 6 yes
GO:0000295 adenine nucleotide transmembrane transporter activity 6.8966 6 yes
GO:0005346 purine ribonucleotide transmembrane transporter activity 6.8966 4 yes
GO:0015215 nucleotide transmembrane transporter activity 6.8966 4 yes
GO:0015216 purine nucleotide transmembrane transporter activity 6.8966 5 yes
GO:0015607 ABC-type fatty-acyl-CoA transporter activity 6.8966 4 yes
GO:0043531 ADP binding 6.8966 4 yes
GO:0071077 adenosine 3,5-bisphosphate transmembrane transporter activity 6.8966 5 yes

Biological process

Term Name % Distance from top the of the tree Annotated in ABCD1_HUMAN
GO:0006996 organelle organization 48.2759 4 yes
GO:0048522 positive regulation of cellular process 41.3793 4 yes
GO:0071702 organic substance transport 31.0345 4 yes
GO:0022607 cellular component assembly 31.0345 4 no
GO:0060255 regulation of macromolecule metabolic process 27.5862 4 yes
GO:0008104 protein localization 27.5862 4 no
GO:0048523 negative regulation of cellular process 27.5862 4 yes
GO:0061024 membrane organization 24.1379 4 yes
GO:0080090 regulation of primary metabolic process 24.1379 4 yes
GO:0051049 regulation of transport 24.1379 4 no
GO:0009893 positive regulation of metabolic process 24.1379 4 yes
GO:0030030 cell projection organization 24.1379 4 yes
GO:0048878 chemical homeostasis 24.1379 4 yes
GO:0120036 plasma membrane bounded cell projection organization 20.6897 5 yes
GO:0007005 mitochondrion organization 20.6897 5 no
GO:0010646 regulation of cell communication 20.6897 4 no
GO:0051128 regulation of cellular component organization 20.6897 4 no
GO:0071705 nitrogen compound transport 20.6897 4 no
GO:0006796 phosphate-containing compound metabolic process 20.6897 4 yes
GO:0009892 negative regulation of metabolic process 20.6897 4 yes
GO:0010468 regulation of gene expression 20.6897 5 yes
GO:0031323 regulation of cellular metabolic process 20.6897 4 yes
GO:0031324 negative regulation of cellular metabolic process 20.6897 5 yes
GO:0043603 cellular amide metabolic process 20.6897 4 yes
GO:0072521 purine-containing compound metabolic process 17.2414 4 yes
GO:0006163 purine nucleotide metabolic process 17.2414 5 yes
GO:0006631 fatty acid metabolic process 17.2414 4 yes
GO:0006753 nucleoside phosphate metabolic process 17.2414 4 yes
GO:0008610 lipid biosynthetic process 17.2414 4 yes
GO:0009117 nucleotide metabolic process 17.2414 5 yes
GO:0009150 purine ribonucleotide metabolic process 17.2414 6 yes
GO:0009259 ribonucleotide metabolic process 17.2414 5 yes
GO:0009889 regulation of biosynthetic process 17.2414 4 yes
GO:0019693 ribose phosphate metabolic process 17.2414 4 yes
GO:0019752 carboxylic acid metabolic process 17.2414 5 yes
GO:0031326 regulation of cellular biosynthetic process 17.2414 5 yes
GO:0032787 monocarboxylic acid metabolic process 17.2414 6 yes
GO:0043436 oxoacid metabolic process 17.2414 4 yes
GO:0072330 monocarboxylic acid biosynthetic process 13.7931 6 yes
GO:1901568 fatty acid derivative metabolic process 13.7931 4 yes
GO:0000038 very long-chain fatty acid metabolic process 13.7931 5 yes
GO:0001676 long-chain fatty acid metabolic process 13.7931 5 yes
GO:0006633 fatty acid biosynthetic process 13.7931 5 yes
GO:0006869 lipid transport 13.7931 5 yes
GO:0007031 peroxisome organization 13.7931 5 yes
GO:0009890 negative regulation of biosynthetic process 13.7931 5 yes
GO:0009891 positive regulation of biosynthetic process 13.7931 5 yes
GO:0009894 regulation of catabolic process 13.7931 4 yes
GO:0010605 negative regulation of macromolecule metabolic process 13.7931 5 yes
GO:0016042 lipid catabolic process 13.7931 4 yes
GO:0016053 organic acid biosynthetic process 13.7931 4 yes
GO:0031325 positive regulation of cellular metabolic process 13.7931 5 yes
GO:0031328 positive regulation of cellular biosynthetic process 13.7931 6 yes
GO:0046394 carboxylic acid biosynthetic process 13.7931 5 yes
GO:0051241 negative regulation of multicellular organismal process 13.7931 4 yes
GO:0062012 regulation of small molecule metabolic process 10.3448 4 yes
GO:0072329 monocarboxylic acid catabolic process 10.3448 6 yes
GO:1901565 organonitrogen compound catabolic process 10.3448 4 yes
GO:1902001 fatty acid transmembrane transport 10.3448 5 yes
GO:1903426 regulation of reactive oxygen species biosynthetic process 10.3448 5 yes
GO:1903427 negative regulation of reactive oxygen species biosynthetic process 10.3448 6 yes
GO:1903715 regulation of aerobic respiration 10.3448 7 yes
GO:1905039 carboxylic acid transmembrane transport 10.3448 4 yes
GO:2000377 regulation of reactive oxygen species metabolic process 10.3448 5 yes
GO:2000378 negative regulation of reactive oxygen species metabolic process 10.3448 6 yes
GO:0001817 regulation of cytokine production 10.3448 4 yes
GO:0002082 regulation of oxidative phosphorylation 10.3448 8 yes
GO:0006635 fatty acid beta-oxidation 10.3448 6 yes
GO:0006637 acyl-CoA metabolic process 10.3448 4 yes
GO:0009062 fatty acid catabolic process 10.3448 5 yes
GO:0009896 positive regulation of catabolic process 10.3448 5 yes
GO:0010629 negative regulation of gene expression 10.3448 6 yes
GO:0015849 organic acid transport 10.3448 5 yes
GO:0015908 fatty acid transport 10.3448 6 yes
GO:0015909 long-chain fatty acid transport 10.3448 7 yes
GO:0015910 long-chain fatty acid import into peroxisome 10.3448 5 yes
GO:0015919 peroxisomal membrane transport 10.3448 5 yes
GO:0016054 organic acid catabolic process 10.3448 4 yes
GO:0019395 fatty acid oxidation 10.3448 5 yes
GO:0030258 lipid modification 10.3448 4 yes
GO:0031329 regulation of cellular catabolic process 10.3448 5 yes
GO:0032365 intracellular lipid transport 10.3448 4 yes
GO:0033865 nucleoside bisphosphate metabolic process 10.3448 5 yes
GO:0033875 ribonucleoside bisphosphate metabolic process 10.3448 6 yes
GO:0034032 purine nucleoside bisphosphate metabolic process 10.3448 5 yes
GO:0034440 lipid oxidation 10.3448 5 yes
GO:0035337 fatty-acyl-CoA metabolic process 10.3448 5 yes
GO:0042760 very long-chain fatty acid catabolic process 10.3448 6 yes
GO:0043457 regulation of cellular respiration 10.3448 6 yes
GO:0043467 regulation of generation of precursor metabolites and energy 10.3448 5 yes
GO:0043574 peroxisomal transport 10.3448 4 yes
GO:0044242 cellular lipid catabolic process 10.3448 4 yes
GO:0046395 carboxylic acid catabolic process 10.3448 5 yes
GO:0051881 regulation of mitochondrial membrane potential 10.3448 4 yes
GO:0055089 fatty acid homeostasis 6.8966 6 yes
GO:0055092 sterol homeostasis 6.8966 6 yes
GO:0062013 positive regulation of small molecule metabolic process 6.8966 5 yes
GO:0072523 purine-containing compound catabolic process 6.8966 5 yes
GO:0080134 regulation of response to stress 6.8966 4 yes
GO:0080135 regulation of cellular response to stress 6.8966 4 yes
GO:0106027 neuron projection organization 6.8966 6 yes
GO:1900015 regulation of cytokine production involved in inflammatory response 6.8966 5 yes
GO:1900016 negative regulation of cytokine production involved in inflammatory response 6.8966 6 yes
GO:1900407 regulation of cellular response to oxidative stress 6.8966 5 yes
GO:1901136 carbohydrate derivative catabolic process 6.8966 4 yes
GO:1901292 nucleoside phosphate catabolic process 6.8966 5 yes
GO:1901361 organic cyclic compound catabolic process 6.8966 4 yes
GO:1901569 fatty acid derivative catabolic process 6.8966 5 yes
GO:1902882 regulation of response to oxidative stress 6.8966 5 yes
GO:1990535 neuron projection maintenance 6.8966 7 yes
GO:2001279 regulation of unsaturated fatty acid biosynthetic process 6.8966 7 yes
GO:2001280 positive regulation of unsaturated fatty acid biosynthetic process 6.8966 8 yes
GO:0001818 negative regulation of cytokine production 6.8966 5 yes
GO:0003254 regulation of membrane depolarization 6.8966 4 yes
GO:0006195 purine nucleotide catabolic process 6.8966 6 yes
GO:0007009 plasma membrane organization 6.8966 5 yes
GO:0009154 purine ribonucleotide catabolic process 6.8966 6 yes
GO:0009166 nucleotide catabolic process 6.8966 6 yes
GO:0009261 ribonucleotide catabolic process 6.8966 5 yes
GO:0010565 regulation of cellular ketone metabolic process 6.8966 5 yes
GO:0019216 regulation of lipid metabolic process 6.8966 5 yes
GO:0019217 regulation of fatty acid metabolic process 6.8966 6 yes
GO:0019439 aromatic compound catabolic process 6.8966 4 yes
GO:0030497 fatty acid elongation 6.8966 6 yes
GO:0031331 positive regulation of cellular catabolic process 6.8966 6 yes
GO:0031998 regulation of fatty acid beta-oxidation 6.8966 6 yes
GO:0032000 positive regulation of fatty acid beta-oxidation 6.8966 7 yes
GO:0033559 unsaturated fatty acid metabolic process 6.8966 5 yes
GO:0033869 nucleoside bisphosphate catabolic process 6.8966 6 yes
GO:0034031 ribonucleoside bisphosphate catabolic process 6.8966 7 yes
GO:0034034 purine nucleoside bisphosphate catabolic process 6.8966 6 yes
GO:0034655 nucleobase-containing compound catabolic process 6.8966 4 yes
GO:0036109 alpha-linolenic acid metabolic process 6.8966 4 yes
GO:0036111 very long-chain fatty-acyl-CoA metabolic process 6.8966 6 yes
GO:0036113 very long-chain fatty-acyl-CoA catabolic process 6.8966 6 yes
GO:0036115 fatty-acyl-CoA catabolic process 6.8966 5 yes
GO:0042304 regulation of fatty acid biosynthetic process 6.8966 6 yes
GO:0042758 long-chain fatty acid catabolic process 6.8966 6 yes
GO:0043217 myelin maintenance 6.8966 6 yes
GO:0043651 linoleic acid metabolic process 6.8966 4 yes
GO:0044270 cellular nitrogen compound catabolic process 6.8966 4 yes
GO:0044273 sulfur compound catabolic process 6.8966 4 yes
GO:0045723 positive regulation of fatty acid biosynthetic process 6.8966 7 yes
GO:0045834 positive regulation of lipid metabolic process 6.8966 5 yes
GO:0045923 positive regulation of fatty acid metabolic process 6.8966 6 yes
GO:0046320 regulation of fatty acid oxidation 6.8966 7 yes
GO:0046321 positive regulation of fatty acid oxidation 6.8966 7 yes
GO:0046434 organophosphate catabolic process 6.8966 4 yes
GO:0046700 heterocycle catabolic process 6.8966 4 yes
GO:0046889 positive regulation of lipid biosynthetic process 6.8966 6 yes
GO:0046890 regulation of lipid biosynthetic process 6.8966 5 yes
GO:0050994 regulation of lipid catabolic process 6.8966 5 yes
GO:0050996 positive regulation of lipid catabolic process 6.8966 6 yes
GO:0051900 regulation of mitochondrial depolarization 6.8966 5 yes
GO:0055088 lipid homeostasis 6.8966 5 yes

Disease

Term Name % Distance from top the of the tree Annotated in ABCD1_HUMAN
DOID:10579 leukodystrophy 6.8966 6 yes
DOID:10588 adrenoleukodystrophy 6.8966 7 yes
DOID:1443 cerebral degeneration 6.8966 5 yes
DOID:331 central nervous system disease 6.8966 3 yes
DOID:936 brain disease 6.8966 4 yes
DOID:0050539 Charcot-Marie-Tooth disease type 2 6.8966 7 no
DOID:10595 Charcot-Marie-Tooth disease 6.8966 6 no
DOID:440 neuromuscular disease 6.8966 5 no
DOID:574 peripheral nervous system disease 6.8966 3 no
DOID:870 neuropathy 6.8966 4 no

All partners

Uniprot ID Details Highest evidence Localizing into PSD HPA (protein expression in neurons)
PEX19_HUMAN [view interactions] Low throughput no yes
ABCD1_HUMAN [view entry] [view interactions] Low throughput yes no
ABCD2_HUMAN [view interactions] Low throughput no no
ABCD3_HUMAN [view entry] [view interactions] Low throughput yes yes
S27A2_HUMAN [view interactions] Low throughput no no
RSSA_HUMAN [view entry] [view interactions] High throughput yes yes
RAB5C_HUMAN [view entry] [view interactions] High throughput yes yes
RAB7A_HUMAN [view entry] [view interactions] High throughput yes yes
VAPA_HUMAN [view entry] [view interactions] High throughput yes yes
VP26B_HUMAN [view interactions] High throughput no yes
MAS_HUMAN [view interactions] High throughput no no
APJ_HUMAN [view interactions] High throughput no yes
S15A1_HUMAN [view interactions] High throughput no no
VASN_HUMAN [view interactions] High throughput no yes
SCN3B_HUMAN [view interactions] High throughput no no
ROAA_HUMAN [view interactions] High throughput no yes
TERF2_HUMAN [view interactions] High throughput no yes
POTE1_HUMAN [view interactions] High throughput no no
BASI_HUMAN [view entry] [view interactions] High throughput yes no
S39A4_HUMAN [view interactions] High throughput no no
IQCF1_HUMAN [view interactions] High throughput no no
NTRK1_HUMAN [view interactions] High throughput no yes
AT2B2_HUMAN [view entry] [view interactions] High throughput yes yes
S39AC_HUMAN [view interactions] High throughput no no
TRI25_HUMAN [view interactions] High throughput no yes
RNF4_HUMAN [view interactions] High throughput no yes
LMBRL_HUMAN [view interactions] High throughput no no
EMC4_HUMAN [view interactions] High throughput no yes
ANLN_HUMAN [view interactions] High throughput no yes
ECT2_HUMAN [view interactions] High throughput no no
KIF14_HUMAN [view interactions] High throughput no no
KI20A_HUMAN [view interactions] High throughput no yes
KIF23_HUMAN [view interactions] High throughput no yes
FBX6_HUMAN [view interactions] High throughput no yes
GPR12_HUMAN [view interactions] High throughput no no
HUMMR_HUMAN [view interactions] High throughput no yes
SAAL1_HUMAN [view interactions] High throughput no yes
PBIP1_HUMAN [view entry] [view interactions] High throughput yes no
CREL1_HUMAN [view interactions] High throughput no yes
AT2A1_HUMAN [view entry] [view interactions] High throughput yes no
CTLA4_HUMAN [view interactions] High throughput no no
CKLF8_HUMAN [view interactions] High throughput no yes
TMEM9_HUMAN [view interactions] High throughput no no
AT2A3_HUMAN [view interactions] High throughput no yes
TTYH1_HUMAN [view entry] [view interactions] High throughput yes no
AKAP1_HUMAN [view entry] [view interactions] High throughput yes yes
CKLF5_HUMAN [view interactions] High throughput no yes
BACE2_HUMAN [view interactions] High throughput no yes
S10A2_HUMAN [view interactions] High throughput no no
GP182_HUMAN [view interactions] High throughput no no
EFMT3_HUMAN [view interactions] High throughput no no
BCL2_HUMAN [view interactions] High throughput no no
CIA2A_HUMAN [view interactions] High throughput no yes
DC1I2_HUMAN [view entry] [view interactions] High throughput yes yes
FSCN1_HUMAN [view entry] [view interactions] High throughput yes yes
RHOA_HUMAN [view entry] [view interactions] High throughput yes yes
RND2_HUMAN [view interactions] High throughput no no
TP4A3_HUMAN [view interactions] High throughput no no
PEX3_HUMAN [view interactions] High throughput no yes
NDUAC_HUMAN [view entry] [view interactions] High throughput yes yes
NDUB4_HUMAN [view entry] [view interactions] High throughput yes yes
ADAS_HUMAN [view interactions] High throughput no yes
ITPR3_HUMAN [view interactions] High throughput no yes
ELAV1_HUMAN [view entry] [view interactions] High throughput yes yes
MIC19_HUMAN [view entry] [view interactions] High throughput yes yes
MIC60_HUMAN [view entry] [view interactions] High throughput yes yes
NDUS1_HUMAN [view entry] [view interactions] High throughput yes no
AL3A2_HUMAN [view entry] [view interactions] Computational yes yes
PX11B_HUMAN [view entry] [view interactions] Computational yes yes
PXMP4_HUMAN [view interactions] Computational no yes
PM34_HUMAN [view interactions] Computational no yes
ACBG1_HUMAN [view entry] [view interactions] Computational yes yes
PEX13_HUMAN [view interactions] Computational no yes
GDAP1_HUMAN [view entry] [view interactions] Computational yes yes
ACBD5_HUMAN [view entry] [view interactions] Computational yes yes
PXMP2_HUMAN [view interactions] Computational no no
ATAD1_HUMAN [view entry] [view interactions] Computational yes yes
PEX16_HUMAN [view interactions] Computational no yes
PEX14_HUMAN [view interactions] Computational no yes
PEX2_HUMAN [view interactions] Computational no yes
FIS1_HUMAN [view entry] [view interactions] Computational yes yes
PEX26_HUMAN [view interactions] Computational no yes