Features Interactions Isoform Disease Linear motifs Fingerprint Network All partners

NDUAC_HUMAN

Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. [View more on UniProt]

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No data found.

No annotated instance was found. To search for linear motifs, use the ELM prediction server.

Molecular function

Term Name % Distance from the top of the tree Annotated in NDUAC_HUMAN
GO:0008324 monoatomic cation transmembrane transporter activity 32.9412 4 yes
GO:0015399 primary active transmembrane transporter activity 32.9412 4 yes
GO:0022853 active monoatomic ion transmembrane transporter activity 32.9412 4 yes
GO:0022890 inorganic cation transmembrane transporter activity 32.9412 4 yes
GO:0015078 proton transmembrane transporter activity 31.7647 5 yes
GO:0015453 oxidoreduction-driven active transmembrane transporter activity 30.5882 5 yes
GO:0043169 cation binding 30.5882 4 no
GO:0046872 metal ion binding 29.4118 5 no
GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor 25.8824 4 yes
GO:0000166 nucleotide binding 21.1765 4 no
GO:0003723 RNA binding 21.1765 4 no

Biological process

Term Name % Distance from top the of the tree Annotated in NDUAC_HUMAN
GO:0022607 cellular component assembly 41.1765 4 yes
GO:0006796 phosphate-containing compound metabolic process 38.8235 4 yes
GO:0009060 aerobic respiration 37.6471 6 yes
GO:0015980 energy derivation by oxidation of organic compounds 37.6471 4 yes
GO:0022900 electron transport chain 37.6471 4 yes
GO:0022904 respiratory electron transport chain 37.6471 5 yes
GO:0045333 cellular respiration 37.6471 5 yes
GO:0043933 protein-containing complex organization 35.2941 4 yes
GO:0006753 nucleoside phosphate metabolic process 34.1176 4 yes
GO:0009117 nucleotide metabolic process 34.1176 5 yes
GO:0065003 protein-containing complex assembly 34.1176 5 yes
GO:0019646 aerobic electron transport chain 34.1176 6 no
GO:0006163 purine nucleotide metabolic process 32.9412 5 yes
GO:0072521 purine-containing compound metabolic process 32.9412 4 yes
GO:0009150 purine ribonucleotide metabolic process 31.7647 6 yes
GO:0009259 ribonucleotide metabolic process 31.7647 5 yes
GO:0019693 ribose phosphate metabolic process 31.7647 4 yes
GO:1901362 organic cyclic compound biosynthetic process 30.5882 4 yes
GO:1901566 organonitrogen compound biosynthetic process 30.5882 4 yes
GO:0048522 positive regulation of cellular process 29.4118 4 no
GO:0034654 nucleobase-containing compound biosynthetic process 28.2353 4 yes
GO:0090407 organophosphate biosynthetic process 28.2353 4 yes
GO:0031323 regulation of cellular metabolic process 28.2353 4 no
GO:0006164 purine nucleotide biosynthetic process 27.0588 6 yes
GO:0009141 nucleoside triphosphate metabolic process 27.0588 5 yes
GO:0009144 purine nucleoside triphosphate metabolic process 27.0588 6 yes
GO:0009152 purine ribonucleotide biosynthetic process 27.0588 7 yes
GO:0009165 nucleotide biosynthetic process 27.0588 6 yes
GO:0009199 ribonucleoside triphosphate metabolic process 27.0588 6 yes
GO:0009205 purine ribonucleoside triphosphate metabolic process 27.0588 7 yes
GO:0009260 ribonucleotide biosynthetic process 27.0588 6 yes
GO:0046034 ATP metabolic process 27.0588 7 yes
GO:0046390 ribose phosphate biosynthetic process 27.0588 5 yes
GO:0072522 purine-containing compound biosynthetic process 27.0588 5 yes
GO:1901137 carbohydrate derivative biosynthetic process 27.0588 4 yes
GO:1901293 nucleoside phosphate biosynthetic process 27.0588 5 yes
GO:0006996 organelle organization 27.0588 4 no
GO:0048523 negative regulation of cellular process 25.8824 4 no
GO:0060255 regulation of macromolecule metabolic process 25.8824 4 no
GO:0006754 ATP biosynthetic process 24.7059 8 yes
GO:0009142 nucleoside triphosphate biosynthetic process 24.7059 6 yes
GO:0009145 purine nucleoside triphosphate biosynthetic process 24.7059 7 yes
GO:0009201 ribonucleoside triphosphate biosynthetic process 24.7059 7 yes
GO:0009206 purine ribonucleoside triphosphate biosynthetic process 24.7059 8 yes
GO:0015986 proton motive force-driven ATP synthesis 24.7059 9 yes
GO:0042776 proton motive force-driven mitochondrial ATP synthesis 24.7059 10 yes
GO:0010646 regulation of cell communication 24.7059 4 no
GO:0080090 regulation of primary metabolic process 24.7059 4 no
GO:0006120 mitochondrial electron transport, NADH to ubiquinone 23.5294 7 no
GO:0051128 regulation of cellular component organization 23.5294 4 no
GO:0033108 mitochondrial respiratory chain complex assembly 22.3529 6 yes
GO:0009966 regulation of signal transduction 22.3529 4 no
GO:0010257 NADH dehydrogenase complex assembly 20.0000 6 yes
GO:0032981 mitochondrial respiratory chain complex I assembly 20.0000 7 yes
GO:0042773 ATP synthesis coupled electron transport 5.8824 6 yes
GO:0042775 mitochondrial ATP synthesis coupled electron transport 5.8824 7 yes

Disease

No data found.

Uniprot ID Details Highest evidence Localizing into PSD HPA (protein expression in neurons)
NDUS3_HUMAN [view entry] [view interactions] Low throughput yes yes
NDUS8_HUMAN [view interactions] Low throughput no yes
NDUA5_HUMAN [view entry] [view interactions] Low throughput yes yes
NDUS7_HUMAN [view entry] [view interactions] Low throughput yes no
NDUA2_HUMAN [view entry] [view interactions] Low throughput yes yes
ACPM_HUMAN [view interactions] Low throughput no yes
NDUA6_HUMAN [view interactions] Low throughput no no
NDUAD_HUMAN [view entry] [view interactions] Low throughput yes yes
NDUS6_HUMAN [view entry] [view interactions] Low throughput yes yes
NDUS4_HUMAN [view interactions] Low throughput no yes
NDUS1_HUMAN [view entry] [view interactions] Low throughput yes no
NDUV1_HUMAN [view entry] [view interactions] Low throughput yes yes
NDUV2_HUMAN [view entry] [view interactions] Low throughput yes yes
NDUA9_HUMAN [view entry] [view interactions] Low throughput yes yes
NDUV3_HUMAN [view interactions] Low throughput no yes
NDUS2_HUMAN [view entry] [view interactions] Low throughput yes yes
NDUA7_HUMAN [view entry] [view interactions] Low throughput yes yes
NDUB4_HUMAN [view entry] [view interactions] High throughput yes yes
NU1M_HUMAN [view interactions] High throughput no yes
NDUBB_HUMAN [view interactions] High throughput no yes
NDUA4_HUMAN [view entry] [view interactions] High throughput yes yes
NDUS5_HUMAN [view interactions] High throughput no yes
CIA30_HUMAN [view interactions] High throughput no yes
TIDC1_HUMAN [view interactions] High throughput no yes
BMR1A_HUMAN [view interactions] High throughput no no
RAB5C_HUMAN [view entry] [view interactions] High throughput yes yes
RMD3_HUMAN [view entry] [view interactions] High throughput yes yes
TMED2_HUMAN [view interactions] High throughput no yes
VAPA_HUMAN [view entry] [view interactions] High throughput yes yes
EMC5_HUMAN [view interactions] High throughput no yes
GOT1B_HUMAN [view interactions] High throughput no yes
YIPF3_HUMAN [view interactions] High throughput no yes
C3AR_HUMAN [view interactions] High throughput no no
VAPB_HUMAN [view entry] [view interactions] High throughput yes yes
GDPD5_HUMAN [view interactions] High throughput no no
YBEY_HUMAN [view interactions] High throughput no yes
NDUA8_HUMAN [view entry] [view interactions] High throughput yes yes
IL1R2_HUMAN [view interactions] High throughput no no
GALT6_HUMAN [view interactions] High throughput no yes
NMES1_HUMAN [view interactions] High throughput no no
SYUA_HUMAN [view entry] [view interactions] High throughput yes no
LRP4_HUMAN [view entry] [view interactions] High throughput yes yes
HSC20_HUMAN [view interactions] High throughput no yes
KCNQ1_HUMAN [view interactions] High throughput no yes
KCNH2_HUMAN [view interactions] High throughput no no
CAV3_HUMAN [view interactions] High throughput no no
ITM2B_HUMAN [view interactions] High throughput no yes
MY15B_HUMAN [view interactions] High throughput no no
SYT4_HUMAN [view entry] [view interactions] High throughput yes yes
TMED8_HUMAN [view interactions] High throughput no no
ESR1_HUMAN [view interactions] High throughput no no
ATD3A_HUMAN [view entry] [view interactions] High throughput yes yes
MDM2_HUMAN [view entry] [view interactions] High throughput yes yes
AKIP_HUMAN [view interactions] High throughput no yes
CH60_HUMAN [view entry] [view interactions] High throughput yes yes
MGST3_HUMAN [view entry] [view interactions] High throughput yes yes
PDK1_HUMAN [view interactions] High throughput no yes
TR61B_HUMAN [view interactions] High throughput no yes
IMP2L_HUMAN [view interactions] High throughput no yes
HTRA2_HUMAN [view interactions] High throughput no yes
IMP1L_HUMAN [view interactions] High throughput no yes
OMA1_HUMAN [view interactions] High throughput no no
PARL_HUMAN [view interactions] High throughput no yes
FHI2B_HUMAN [view interactions] High throughput no yes
CFTR_HUMAN [view interactions] High throughput no no
TRM1_HUMAN [view interactions] High throughput no yes
GP107_HUMAN [view interactions] High throughput no yes
ESR2_HUMAN [view interactions] High throughput no no
HEXI1_HUMAN [view interactions] High throughput no yes
NEB2_HUMAN [view entry] [view interactions] High throughput yes yes
TAU_HUMAN [view entry] [view interactions] High throughput yes yes
LMBRL_HUMAN [view interactions] High throughput no no
PKHA4_HUMAN [view interactions] High throughput no yes
INS_HUMAN [view interactions] High throughput no no
CFAD_HUMAN [view interactions] High throughput no no
FNDC5_HUMAN [view interactions] High throughput no no
DX39A_HUMAN [view interactions] High throughput no yes
NDUC2_HUMAN [view interactions] High throughput no yes
CREL1_HUMAN [view interactions] High throughput no yes
S22A4_HUMAN [view interactions] High throughput no yes
TSH2_HUMAN [view interactions] High throughput no yes
CXA8_HUMAN [view interactions] High throughput no no
AQP3_HUMAN [view interactions] High throughput no no
NDUA1_HUMAN [view interactions] High throughput no yes
DQB1_HUMAN [view interactions] High throughput no no
CP2J2_HUMAN [view interactions] High throughput no no
EXTL3_HUMAN [view interactions] High throughput no yes
HDBP1_HUMAN [view interactions] High throughput no no
WIF1_HUMAN [view entry] [view interactions] High throughput yes no
DJC30_HUMAN [view interactions] High throughput no no
DRB1_HUMAN [view interactions] High throughput no no
NTNG1_HUMAN [view interactions] High throughput no no
EMP3_HUMAN [view interactions] High throughput no no
NRP1_HUMAN [view entry] [view interactions] High throughput yes yes
BASI_HUMAN [view entry] [view interactions] High throughput yes no
RHOG_HUMAN [view entry] [view interactions] High throughput yes no
BAIP2_HUMAN [view entry] [view interactions] High throughput yes yes
FOXA1_HUMAN [view interactions] High throughput no no
E2F4_HUMAN [view interactions] High throughput no no
ZRAN1_HUMAN [view interactions] High throughput no yes
PRRT2_HUMAN [view entry] [view interactions] High throughput yes no
ADA10_HUMAN [view entry] [view interactions] High throughput yes yes
AAK1_HUMAN [view entry] [view interactions] High throughput yes yes
BMP2K_HUMAN [view interactions] High throughput no yes
CL16A_HUMAN [view interactions] High throughput no yes
MIDN_HUMAN [view interactions] High throughput no no
SPOP_HUMAN [view interactions] High throughput no no
ATP5H_HUMAN [view interactions] High throughput no yes
CY1_HUMAN [view entry] [view interactions] High throughput yes yes
ATPG_HUMAN [view interactions] High throughput no yes
ATPB_HUMAN [view interactions] High throughput no yes
SURF1_HUMAN [view interactions] High throughput no yes
RM15_HUMAN [view interactions] High throughput no yes
ABCD1_HUMAN [view entry] [view interactions] High throughput yes no
MPV17_HUMAN [view interactions] High throughput no no
ERLN1_HUMAN [view entry] [view interactions] High throughput yes yes
COX15_HUMAN [view interactions] High throughput no yes
TOM22_HUMAN [view interactions] High throughput no yes
AT1B1_HUMAN [view entry] [view interactions] High throughput yes no
AT1B3_HUMAN [view interactions] High throughput no yes
CISD1_HUMAN [view entry] [view interactions] High throughput yes yes
MTCH2_HUMAN [view entry] [view interactions] High throughput yes yes
NDUAA_HUMAN [view entry] [view interactions] High throughput yes yes
RPN1_HUMAN [view entry] [view interactions] High throughput yes yes
SDHB_HUMAN [view interactions] High throughput no yes
S25A3_HUMAN [view entry] [view interactions] High throughput yes no
QCR7_HUMAN [view entry] [view interactions] High throughput yes yes
QCR2_HUMAN [view entry] [view interactions] High throughput yes yes
VDAC2_HUMAN [view entry] [view interactions] High throughput yes yes
CYB5B_HUMAN [view entry] [view interactions] High throughput yes yes
CX6B1_HUMAN [view entry] [view interactions] High throughput yes yes
SDHA_HUMAN [view interactions] High throughput no yes
ACON_HUMAN [view entry] [view interactions] High throughput yes yes
ATPD_HUMAN [view interactions] High throughput no yes
AT5L2_HUMAN [view interactions] High throughput no no
ATP5L_HUMAN [view interactions] High throughput no yes
CISY_HUMAN [view entry] [view interactions] High throughput yes yes
ODP2_HUMAN [view entry] [view interactions] High throughput yes yes
IDH3A_HUMAN [view entry] [view interactions] High throughput yes yes
ATP5I_HUMAN [view interactions] High throughput no yes
COX5A_HUMAN [view entry] [view interactions] High throughput yes yes
CYC_HUMAN [view entry] [view interactions] High throughput yes yes
QCR6L_HUMAN [view interactions] High throughput no yes
PARK7_HUMAN [view entry] [view interactions] High throughput yes yes
SUCB1_HUMAN [view entry] [view interactions] High throughput yes yes
MRM1_HUMAN [view interactions] High throughput no no
OTULL_HUMAN [view interactions] High throughput no no
GRSF1_HUMAN [view interactions] High throughput no yes
ACAD9_HUMAN [view interactions] High throughput no yes
AUHM_HUMAN [view entry] [view interactions] High throughput yes yes
MTRFR_HUMAN [view interactions] High throughput no yes
CQ080_HUMAN [view interactions] High throughput no yes
C1QBP_HUMAN [view entry] [view interactions] High throughput yes yes
GAL3A_HUMAN [view interactions] High throughput no yes
GAL3B_HUMAN [view interactions] High throughput no no
MRES1_HUMAN [view interactions] High throughput no yes
CH082_HUMAN [view interactions] High throughput no yes
MCUR1_HUMAN [view interactions] High throughput no no
CC90B_HUMAN [view interactions] High throughput no yes
CHCH1_HUMAN [view interactions] High throughput no yes
QOR_HUMAN [view entry] [view interactions] High throughput yes yes
DDX28_HUMAN [view interactions] High throughput no yes
DHX30_HUMAN [view entry] [view interactions] High throughput yes yes
FAKD2_HUMAN [view interactions] High throughput no no
FAKD3_HUMAN [view interactions] High throughput no yes
FAKD5_HUMAN [view interactions] High throughput no yes
EFGM_HUMAN [view interactions] High throughput no yes
RRF2M_HUMAN [view interactions] High throughput no yes
HINT2_HUMAN [view interactions] High throughput no yes
ICT1_HUMAN [view interactions] High throughput no yes
LONM_HUMAN [view entry] [view interactions] High throughput yes yes
LPPRC_HUMAN [view entry] [view interactions] High throughput yes yes
MCU_HUMAN [view interactions] High throughput no yes
MCUB_HUMAN [view interactions] High throughput no no
MDHM_HUMAN [view entry] [view interactions] High throughput yes yes
MET15_HUMAN [view interactions] High throughput no no
MET17_HUMAN [view interactions] High throughput no yes
RM11_HUMAN [view interactions] High throughput no yes
RT12_HUMAN [view interactions] High throughput no yes
RT26_HUMAN [view interactions] High throughput no yes
RRFM_HUMAN [view interactions] High throughput no yes
MTEF3_HUMAN [view interactions] High throughput no no
MTG1_HUMAN [view interactions] High throughput no yes
MTG2_HUMAN [view interactions] High throughput no yes
IF2M_HUMAN [view interactions] High throughput no yes
IF3M_HUMAN [view interactions] High throughput no yes
RF1M_HUMAN [view interactions] High throughput no yes
RF1ML_HUMAN [view interactions] High throughput no yes
NGRN_HUMAN [view interactions] High throughput no yes
OTC_HUMAN [view interactions] High throughput no no
MPPA_HUMAN [view interactions] High throughput no yes
MPPB_HUMAN [view interactions] High throughput no yes
RMND1_HUMAN [view interactions] High throughput no yes
RUSD3_HUMAN [view interactions] High throughput no yes
RUSD4_HUMAN [view interactions] High throughput no yes
S2551_HUMAN [view interactions] High throughput no no
SLIRP_HUMAN [view interactions] High throughput no yes
SSBP_HUMAN [view entry] [view interactions] High throughput yes yes
TACO1_HUMAN [view interactions] High throughput no yes
FAKD4_HUMAN [view interactions] High throughput no yes
TEFM_HUMAN [view interactions] High throughput no no
TFAM_HUMAN [view entry] [view interactions] High throughput yes yes
TMM70_HUMAN [view interactions] High throughput no yes
TRUB2_HUMAN [view interactions] High throughput no yes
EFTS_HUMAN [view interactions] High throughput no no
EFTU_HUMAN [view entry] [view interactions] High throughput yes yes
VWA8_HUMAN [view interactions] High throughput no yes
EXD2_HUMAN [view interactions] High throughput no yes
CLPP_HUMAN [view interactions] High throughput no yes
DNJA3_HUMAN [view entry] [view interactions] High throughput yes yes
DJC15_HUMAN [view interactions] High throughput no no
TIM14_HUMAN [view entry] [view interactions] High throughput yes yes
DJC28_HUMAN [view interactions] High throughput no yes
GRP75_HUMAN [view entry] [view interactions] High throughput yes yes
SYAM_HUMAN [view interactions] High throughput no yes
COX8A_HUMAN [view interactions] High throughput no yes
ODPA_HUMAN [view entry] [view interactions] High throughput yes yes
STING_HUMAN [view interactions] High throughput no yes
ETFB_HUMAN [view entry] [view interactions] High throughput yes yes
ZN768_HUMAN [view interactions] High throughput no yes
QCR6_HUMAN [view interactions] High throughput no yes
NDUB9_HUMAN [view entry] [view interactions] High throughput yes yes
COX6C_HUMAN [view entry] [view interactions] High throughput yes yes
NDUB7_HUMAN [view entry] [view interactions] High throughput yes yes
NDUB5_HUMAN [view interactions] High throughput no yes
BAD_HUMAN [view entry] [view interactions] High throughput yes yes
MIC60_HUMAN [view entry] [view interactions] High throughput yes yes
NDUB3_HUMAN [view interactions] High throughput no yes
NDUB8_HUMAN [view entry] [view interactions] High throughput yes yes
NDUB6_HUMAN [view entry] [view interactions] High throughput yes yes
QCR1_HUMAN [view entry] [view interactions] High throughput yes yes
NU5M_HUMAN [view interactions] High throughput no no
NDUAB_HUMAN [view interactions] High throughput no no
MIC27_HUMAN [view entry] [view interactions] High throughput yes yes
NDUBA_HUMAN [view entry] [view interactions] High throughput yes yes
UCRI_HUMAN [view entry] [view interactions] High throughput yes yes