Features Interactions Isoform Disease Linear motifs Fingerprint Network All partners

NDUV2_HUMAN

Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. [View more on UniProt]

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No data found.

No annotated instance was found. To search for linear motifs, use the ELM prediction server.

Molecular function

Term Name % Distance from the top of the tree Annotated in NDUV2_HUMAN
GO:0015399 primary active transmembrane transporter activity 30.4762 4 yes
GO:0015453 oxidoreduction-driven active transmembrane transporter activity 29.5238 5 yes
GO:0046872 metal ion binding 28.5714 4 yes
GO:0003954 NADH dehydrogenase activity 22.8571 4 yes
GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor 22.8571 4 yes
GO:0003955 NAD(P)H dehydrogenase (quinone) activity 21.9048 5 yes
GO:0008137 NADH dehydrogenase (ubiquinone) activity 21.9048 4 yes
GO:0050136 NADH dehydrogenase (quinone) activity 21.9048 5 yes
GO:0003723 RNA binding 21.9048 4 no
GO:0051537 2 iron, 2 sulfur cluster binding 2.8571 4 yes

Biological process

Term Name % Distance from top the of the tree Annotated in NDUV2_HUMAN
GO:0022607 cellular component assembly 38.0952 4 no
GO:0009060 aerobic respiration 33.3333 6 yes
GO:0015980 energy derivation by oxidation of organic compounds 33.3333 4 yes
GO:0022900 electron transport chain 33.3333 4 yes
GO:0045333 cellular respiration 33.3333 5 yes
GO:0022904 respiratory electron transport chain 32.3810 5 yes
GO:0019646 aerobic electron transport chain 30.4762 6 yes
GO:0048522 positive regulation of cellular process 30.4762 4 no
GO:0043933 protein-containing complex organization 30.4762 4 no
GO:0031323 regulation of cellular metabolic process 29.5238 4 no
GO:0065003 protein-containing complex assembly 29.5238 5 no
GO:0080090 regulation of primary metabolic process 28.5714 4 no
GO:0051171 regulation of nitrogen compound metabolic process 27.6190 4 no
GO:0060255 regulation of macromolecule metabolic process 26.6667 4 no
GO:0048523 negative regulation of cellular process 26.6667 4 no
GO:0009893 positive regulation of metabolic process 25.7143 4 no
GO:0006996 organelle organization 25.7143 4 no
GO:0051173 positive regulation of nitrogen compound metabolic process 22.8571 5 no
GO:0009966 regulation of signal transduction 21.9048 4 no
GO:0010604 positive regulation of macromolecule metabolic process 21.9048 5 no
GO:0010646 regulation of cell communication 21.9048 4 no
GO:0051128 regulation of cellular component organization 21.9048 4 no
GO:0051246 regulation of protein metabolic process 21.9048 5 no
GO:0006120 mitochondrial electron transport, NADH to ubiquinone 20.9524 7 yes
GO:0007399 nervous system development 2.8571 4 yes

Disease

Term Name % Distance from top the of the tree Annotated in NDUV2_HUMAN
DOID:700 mitochondrial metabolism disease 2.8571 3 no
DOID:0050700 cardiomyopathy 1.9048 4 no
DOID:0060036 intrinsic cardiomyopathy 1.9048 5 no
DOID:114 heart disease 1.9048 3 no
DOID:2843 long QT syndrome 1.9048 6 no
DOID:0060286 combined oxidative phosphorylation deficiency 1.9048 4 no
DOID:10595 Charcot-Marie-Tooth disease 1.9048 6 no
DOID:440 neuromuscular disease 1.9048 5 no
DOID:574 peripheral nervous system disease 1.9048 3 no
DOID:870 neuropathy 1.9048 4 no
Uniprot ID Details Highest evidence Localizing into PSD HPA (protein expression in neurons)
NDUA5_HUMAN [view entry] [view interactions] Low throughput yes yes
NDUAC_HUMAN [view entry] [view interactions] Low throughput yes yes
NDUS3_HUMAN [view entry] [view interactions] Low throughput yes yes
NDUS4_HUMAN [view interactions] Low throughput no yes
NDUA9_HUMAN [view entry] [view interactions] Low throughput yes yes
NDUS6_HUMAN [view entry] [view interactions] Low throughput yes yes
NDUV1_HUMAN [view entry] [view interactions] Low throughput yes yes
NDUS2_HUMAN [view entry] [view interactions] Low throughput yes yes
NDUAD_HUMAN [view entry] [view interactions] Low throughput yes yes
NDUV3_HUMAN [view interactions] Low throughput no yes
NDUS1_HUMAN [view entry] [view interactions] Low throughput yes no
NDUA6_HUMAN [view interactions] Low throughput no no
NDUA2_HUMAN [view entry] [view interactions] Low throughput yes yes
ACPM_HUMAN [view interactions] Low throughput no yes
NDUS8_HUMAN [view interactions] Low throughput no yes
NDUS7_HUMAN [view entry] [view interactions] Low throughput yes no
NDUA7_HUMAN [view entry] [view interactions] Low throughput yes yes
CALX_HUMAN [view entry] [view interactions] High throughput yes yes
P4HA1_HUMAN [view interactions] High throughput no yes
HMOX2_HUMAN [view entry] [view interactions] High throughput yes yes
NCPR_HUMAN [view entry] [view interactions] High throughput yes yes
VATB2_HUMAN [view entry] [view interactions] High throughput yes yes
TERA_HUMAN [view entry] [view interactions] High throughput yes yes
COR1C_HUMAN [view entry] [view interactions] High throughput yes yes
LPPRC_HUMAN [view entry] [view interactions] High throughput yes yes
CY1_HUMAN [view entry] [view interactions] High throughput yes yes
ODBA_HUMAN [view interactions] High throughput no yes
NNTM_HUMAN [view entry] [view interactions] High throughput yes yes
LACTB_HUMAN [view interactions] High throughput no yes
QCR6_HUMAN [view interactions] High throughput no yes
LRC59_HUMAN [view entry] [view interactions] High throughput yes yes
LONM_HUMAN [view entry] [view interactions] High throughput yes yes
EMC2_HUMAN [view interactions] High throughput no yes
ODPB_HUMAN [view entry] [view interactions] High throughput yes yes
ASPH_HUMAN [view interactions] High throughput no yes
ARMX3_HUMAN [view interactions] High throughput no no
CX6A1_HUMAN [view interactions] High throughput no yes
ACON_HUMAN [view entry] [view interactions] High throughput yes yes
AT5F1_HUMAN [view interactions] High throughput no yes
COX41_HUMAN [view entry] [view interactions] High throughput yes yes
CX6B1_HUMAN [view entry] [view interactions] High throughput yes yes
COX7C_HUMAN [view interactions] High throughput no yes
CISY_HUMAN [view entry] [view interactions] High throughput yes yes
LDHB_HUMAN [view entry] [view interactions] High throughput yes yes
MIC26_HUMAN [view entry] [view interactions] High throughput yes yes
ATP5H_HUMAN [view interactions] High throughput no yes
ATPO_HUMAN [view interactions] High throughput no yes
ATPG_HUMAN [view interactions] High throughput no yes
ATPD_HUMAN [view interactions] High throughput no yes
ATP5E_HUMAN [view interactions] High throughput no no
ATP5I_HUMAN [view interactions] High throughput no yes
ATP5J_HUMAN [view interactions] High throughput no yes
ATPK_HUMAN [view interactions] High throughput no yes
AT5L2_HUMAN [view interactions] High throughput no no
ATP5L_HUMAN [view interactions] High throughput no yes
COX5A_HUMAN [view entry] [view interactions] High throughput yes yes
COX6C_HUMAN [view entry] [view interactions] High throughput yes yes
ODP2_HUMAN [view entry] [view interactions] High throughput yes yes
DLDH_HUMAN [view entry] [view interactions] High throughput yes yes
ODO2_HUMAN [view entry] [view interactions] High throughput yes yes
IDH3G_HUMAN [view entry] [view interactions] High throughput yes yes
NDUCR_HUMAN [view interactions] High throughput no yes
PARK7_HUMAN [view entry] [view interactions] High throughput yes yes
QCR9_HUMAN [view interactions] High throughput no no
UCRI_HUMAN [view entry] [view interactions] High throughput yes yes
QCR6L_HUMAN [view interactions] High throughput no yes
ATPMK_HUMAN [view interactions] High throughput no no
SUCB1_HUMAN [view entry] [view interactions] High throughput yes yes
SUCA_HUMAN [view entry] [view interactions] High throughput yes yes
QCR2_HUMAN [view entry] [view interactions] High throughput yes yes
MIC19_HUMAN [view entry] [view interactions] High throughput yes yes
CYC_HUMAN [view entry] [view interactions] High throughput yes yes
VDAC3_HUMAN [view entry] [view interactions] High throughput yes yes
MRM1_HUMAN [view interactions] High throughput no no
GRSF1_HUMAN [view interactions] High throughput no yes
ACAD9_HUMAN [view interactions] High throughput no yes
AUHM_HUMAN [view entry] [view interactions] High throughput yes yes
MTRFR_HUMAN [view interactions] High throughput no yes
CQ080_HUMAN [view interactions] High throughput no yes
C1QBP_HUMAN [view entry] [view interactions] High throughput yes yes
GAL3A_HUMAN [view interactions] High throughput no yes
GAL3B_HUMAN [view interactions] High throughput no yes
MRES1_HUMAN [view interactions] High throughput no yes
CH082_HUMAN [view interactions] High throughput no yes
MCUR1_HUMAN [view interactions] High throughput no no
CC90B_HUMAN [view interactions] High throughput no yes
CHCH1_HUMAN [view interactions] High throughput no yes
COX15_HUMAN [view interactions] High throughput no yes
QOR_HUMAN [view entry] [view interactions] High throughput yes yes
DDX28_HUMAN [view interactions] High throughput no yes
DHX30_HUMAN [view entry] [view interactions] High throughput yes yes
FAKD2_HUMAN [view interactions] High throughput no no
FAKD3_HUMAN [view interactions] High throughput no yes
FAKD5_HUMAN [view interactions] High throughput no yes
EFGM_HUMAN [view interactions] High throughput no yes
RRF2M_HUMAN [view interactions] High throughput no yes
HINT2_HUMAN [view interactions] High throughput no yes
GLUT4_HUMAN [view interactions] High throughput no no
ICT1_HUMAN [view interactions] High throughput no yes
MCU_HUMAN [view interactions] High throughput no yes
MCUB_HUMAN [view interactions] High throughput no no
MDHM_HUMAN [view entry] [view interactions] High throughput yes yes
NDUS5_HUMAN [view interactions] High throughput no yes
MET15_HUMAN [view interactions] High throughput no no
MET17_HUMAN [view interactions] High throughput no yes
NDUAB_HUMAN [view interactions] High throughput no no
RM11_HUMAN [view interactions] High throughput no yes
RT12_HUMAN [view interactions] High throughput no yes
RT26_HUMAN [view interactions] High throughput no yes
RRFM_HUMAN [view interactions] High throughput no yes
NU5M_HUMAN [view interactions] High throughput no no
MTEF3_HUMAN [view interactions] High throughput no no
FMT_HUMAN [view interactions] High throughput no yes
MTG2_HUMAN [view interactions] High throughput no yes
IF2M_HUMAN [view interactions] High throughput no yes
RAB5C_HUMAN [view entry] [view interactions] High throughput yes yes
IF3M_HUMAN [view interactions] High throughput no yes
RMD3_HUMAN [view interactions] High throughput no yes
RF1M_HUMAN [view interactions] High throughput no yes
RAB7A_HUMAN [view entry] [view interactions] High throughput yes yes
RF1ML_HUMAN [view interactions] High throughput no yes
HSF1_HUMAN [view interactions] High throughput no yes
NGRN_HUMAN [view interactions] High throughput no yes
VAPA_HUMAN [view entry] [view interactions] High throughput yes yes
OTC_HUMAN [view interactions] High throughput no no
EMC5_HUMAN [view interactions] High throughput no yes
MPPA_HUMAN [view interactions] High throughput no yes
GOT1B_HUMAN [view interactions] High throughput no yes
MPPB_HUMAN [view interactions] High throughput no yes
HSC20_HUMAN [view interactions] High throughput no yes
RUSD3_HUMAN [view interactions] High throughput no yes
NDUA8_HUMAN [view entry] [view interactions] High throughput yes yes
RUSD4_HUMAN [view interactions] High throughput no yes
NMES1_HUMAN [view interactions] High throughput no no
SLIRP_HUMAN [view interactions] High throughput no yes
NDUA4_HUMAN [view entry] [view interactions] High throughput yes yes
SSBP_HUMAN [view entry] [view interactions] High throughput yes yes
PRD16_HUMAN [view interactions] High throughput no no
TACO1_HUMAN [view interactions] High throughput no yes
FINC_HUMAN [view interactions] High throughput no yes
FAKD4_HUMAN [view interactions] High throughput no yes
VDAC1_HUMAN [view entry] [view interactions] High throughput yes yes
TEFM_HUMAN [view interactions] High throughput no no
SYUA_HUMAN [view entry] [view interactions] High throughput yes no
TFAM_HUMAN [view entry] [view interactions] High throughput yes yes
HD_HUMAN [view entry] [view interactions] High throughput yes yes
TMM70_HUMAN [view interactions] High throughput no yes
SHAN3_HUMAN [view entry] [view interactions] High throughput yes no
TRUB2_HUMAN [view interactions] High throughput no yes
JUN_HUMAN [view interactions] High throughput no yes
EFTS_HUMAN [view interactions] High throughput no no
EFTU_HUMAN [view entry] [view interactions] High throughput yes yes
CAV3_HUMAN [view interactions] High throughput no no
VWA8_HUMAN [view interactions] High throughput no yes
EGLN_HUMAN [view interactions] High throughput no no
EXD2_HUMAN [view interactions] High throughput no yes
ITM2B_HUMAN [view interactions] High throughput no yes
CLPP_HUMAN [view interactions] High throughput no yes
F1142_HUMAN [view interactions] High throughput no yes
MK11_HUMAN [view interactions] High throughput no yes
GOLM1_HUMAN [view interactions] High throughput no yes
GCR_HUMAN [view entry] [view interactions] High throughput yes yes
CCNC_HUMAN [view interactions] High throughput no yes
DNJA3_HUMAN [view entry] [view interactions] High throughput yes yes
HNRPK_HUMAN [view entry] [view interactions] High throughput yes yes
DJC15_HUMAN [view interactions] High throughput no no
FANCG_HUMAN [view interactions] High throughput no yes
TIM14_HUMAN [view entry] [view interactions] High throughput yes yes
CTNB1_HUMAN [view entry] [view interactions] High throughput yes yes
DJC28_HUMAN [view interactions] High throughput no yes
CALM2_HUMAN [view entry] [view interactions] High throughput yes yes
GRP75_HUMAN [view entry] [view interactions] High throughput yes yes
CALM3_HUMAN [view entry] [view interactions] High throughput yes yes
SYAM_HUMAN [view interactions] High throughput no yes
CALM1_HUMAN [view entry] [view interactions] High throughput yes yes
TRAP1_HUMAN [view entry] [view interactions] High throughput yes yes
NP1L3_HUMAN [view interactions] High throughput no no
KT33B_HUMAN [view interactions] High throughput no no
OCLN_HUMAN [view interactions] High throughput no no
OTX1_HUMAN [view interactions] High throughput no no
NHRF3_HUMAN [view interactions] High throughput no no
ZNF19_HUMAN [view interactions] High throughput no no
SNF5_HUMAN [view interactions] High throughput no yes
SMRD1_HUMAN [view interactions] High throughput no yes
SORL_HUMAN [view interactions] High throughput no yes
THIO_HUMAN [view interactions] High throughput no yes
BRK1_HUMAN [view interactions] High throughput no no
RN112_HUMAN [view entry] [view interactions] High throughput yes yes
RBM11_HUMAN [view interactions] High throughput no no
CRLF3_HUMAN [view interactions] High throughput no yes
ATLA1_HUMAN [view entry] [view interactions] High throughput yes yes
KLH20_HUMAN [view interactions] High throughput no yes
PHF19_HUMAN [view interactions] High throughput no no
RAB38_HUMAN [view interactions] High throughput no no
MSRB2_HUMAN [view interactions] High throughput no no
SLU7_HUMAN [view interactions] High throughput no yes
JADE3_HUMAN [view interactions] High throughput no no
VP26A_HUMAN [view entry] [view interactions] High throughput yes no
PCSK7_HUMAN [view interactions] High throughput no no
IF2B_HUMAN [view interactions] High throughput no yes
PIAS1_HUMAN [view interactions] High throughput no yes
CSN3_HUMAN [view entry] [view interactions] High throughput yes yes
ZN232_HUMAN [view interactions] High throughput no no
THAP1_HUMAN [view interactions] High throughput no no
OTUB1_HUMAN [view interactions] High throughput no yes
WDR61_HUMAN [view interactions] High throughput no yes
RN183_HUMAN [view interactions] High throughput no no
H32_HUMAN [view interactions] High throughput no yes
SPA2L_HUMAN [view entry] [view interactions] High throughput yes yes
LENG8_HUMAN [view interactions] High throughput no yes
H2A3_HUMAN [view interactions] High throughput no yes
PP16A_HUMAN [view interactions] High throughput no no
LNX1_HUMAN [view interactions] High throughput no yes
SPT22_HUMAN [view interactions] High throughput no no
WDR83_HUMAN [view interactions] High throughput no yes
MET27_HUMAN [view interactions] High throughput no yes
LEG9C_HUMAN [view interactions] High throughput no no
ZSC22_HUMAN [view interactions] High throughput no no
VSX2_HUMAN [view interactions] High throughput no no
MAGA2_HUMAN [view interactions] High throughput no no
TBB5_HUMAN [view interactions] High throughput no yes
SPRE2_HUMAN [view interactions] High throughput no yes
SPRE1_HUMAN [view interactions] High throughput no yes
A4_HUMAN [view entry] [view interactions] High throughput yes yes
DPYL1_HUMAN [view entry] [view interactions] High throughput yes yes
KAT5_HUMAN [view interactions] High throughput no yes
SP110_HUMAN [view interactions] High throughput no no
FOXB1_HUMAN [view interactions] High throughput no no
FOXG1_HUMAN [view interactions] High throughput no no
ESR1_HUMAN [view interactions] High throughput no no
TECT3_HUMAN [view interactions] High throughput no yes
AIFM1_HUMAN [view entry] [view interactions] High throughput yes no
AKIP_HUMAN [view interactions] High throughput no yes
CH60_HUMAN [view entry] [view interactions] High throughput yes yes
MGST3_HUMAN [view entry] [view interactions] High throughput yes yes
PDK1_HUMAN [view interactions] High throughput no yes
SFXN1_HUMAN [view entry] [view interactions] High throughput yes yes
TR61B_HUMAN [view interactions] High throughput no yes
IMP2L_HUMAN [view interactions] High throughput no yes
HTRA2_HUMAN [view interactions] High throughput no yes
IMP1L_HUMAN [view interactions] High throughput no yes
OMA1_HUMAN [view interactions] High throughput no no
PARL_HUMAN [view interactions] High throughput no yes
FHI2B_HUMAN [view interactions] High throughput no yes
PLCB1_HUMAN [view entry] [view interactions] High throughput yes yes
STB5L_HUMAN [view interactions] High throughput no no
RASF1_HUMAN [view interactions] High throughput no yes
HCD2_HUMAN [view entry] [view interactions] High throughput yes yes
OXDA_HUMAN [view interactions] High throughput no no
NDUBB_HUMAN [view interactions] High throughput no yes
TIP_HUMAN [view entry] [view interactions] High throughput yes yes
LMBRL_HUMAN [view interactions] High throughput no no
PKHA4_HUMAN [view interactions] High throughput no yes
DPYL2_HUMAN [view entry] [view interactions] High throughput yes yes
KIF14_HUMAN [view interactions] High throughput no no
INS_HUMAN [view interactions] High throughput no no
CFAD_HUMAN [view interactions] High throughput no no
FNDC5_HUMAN [view interactions] High throughput no no
NU1M_HUMAN [view interactions] High throughput no yes
NU4M_HUMAN [view interactions] High throughput no yes
NDUB8_HUMAN [view entry] [view interactions] High throughput yes yes
DJC30_HUMAN [view interactions] High throughput no no
NDUC2_HUMAN [view interactions] High throughput no yes
NDUBA_HUMAN [view entry] [view interactions] High throughput yes yes
NDUB9_HUMAN [view entry] [view interactions] High throughput yes yes
NDUB6_HUMAN [view entry] [view interactions] High throughput yes yes
NDUB7_HUMAN [view entry] [view interactions] High throughput yes yes
NDUB4_HUMAN [view entry] [view interactions] High throughput yes yes
NDUB5_HUMAN [view interactions] High throughput no yes
NDUA1_HUMAN [view interactions] High throughput no yes
NDUB3_HUMAN [view interactions] High throughput no yes
NDUA3_HUMAN [view interactions] High throughput no yes
F185A_HUMAN [view interactions] High throughput no no
STK4_HUMAN [view interactions] High throughput no yes
NDUAA_HUMAN [view entry] [view interactions] High throughput yes yes
NDUB1_HUMAN [view interactions] High throughput no yes
NDUF2_HUMAN [view interactions] High throughput no yes
TRUA_HUMAN [view interactions] High throughput no yes
STK3_HUMAN [view interactions] High throughput no yes
RHOG_HUMAN [view entry] [view interactions] High throughput yes no
CBX1_HUMAN [view interactions] High throughput no yes
NVL_HUMAN [view interactions] High throughput no no
CSK_HUMAN [view interactions] High throughput no yes
QCR1_HUMAN [view entry] [view interactions] High throughput yes yes
NPTN_HUMAN [view entry] [view interactions] High throughput yes yes
SURF1_HUMAN [view interactions] High throughput no yes
PREP_HUMAN [view interactions] High throughput no yes
NOTC2_HUMAN [view interactions] High throughput no yes
TMED9_HUMAN [view interactions] High throughput no yes
NPC2_HUMAN [view interactions] High throughput no yes
HNRPQ_HUMAN [view entry] [view interactions] High throughput yes yes
SUCB2_HUMAN [view interactions] High throughput no no
MPCP_HUMAN [view entry] [view interactions] High throughput yes no
ZO1_HUMAN [view entry] [view interactions] High throughput yes no
SDHB_HUMAN [view interactions] High throughput no yes
SDHA_HUMAN [view interactions] High throughput no yes
SEPT9_HUMAN [view interactions] High throughput no no
PCYOX_HUMAN [view interactions] High throughput no yes
SVIL_HUMAN [view interactions] High throughput no yes
COX2_HUMAN [view entry] [view interactions] High throughput yes yes
TPIS_HUMAN [view entry] [view interactions] High throughput yes yes
QCR10_HUMAN [view interactions] Computational no no
QCR8_HUMAN [view interactions] Computational no yes
CYB_HUMAN [view interactions] Computational no yes
COX1_HUMAN [view interactions] Computational no yes
NU2M_HUMAN [view entry] [view interactions] Computational yes no
NU4LM_HUMAN [view interactions] Computational no no
CIA30_HUMAN [view interactions] Computational no yes
NU3M_HUMAN [view interactions] Computational no yes
FXRD1_HUMAN [view interactions] Computational no no
NU6M_HUMAN [view interactions] Computational no no
NDUB2_HUMAN [view interactions] Computational no yes
MPC1_HUMAN [view interactions] Computational no yes
QCR7_HUMAN [view entry] [view interactions] Computational yes yes
MCAT_HUMAN [view interactions] Computational no yes
COX5B_HUMAN [view entry] [view interactions] Computational yes yes
NDUC1_HUMAN [view interactions] Computational no yes
C560_HUMAN [view interactions] Computational no no