NCPR_HUMAN
Evidence for PS localization
Functions
This enzyme is required for electron transfer from NADP to cytochrome P450 in microsomes. It can also provide electron transfer to heme oxygenase and cytochrome B5. [View more on UniProt]
Protein features
Binary interactions with known binding regions
Interacting region for partners were not defined.
Network
Isoforms
Disease-causing germline mutations
No data found.
Linear motifs
No annotated instance was found. To search for linear motifs, use the ELM prediction server.
Fingerprint
Molecular function
| Term | Name | % | Distance from the top of the tree | Annotated in NCPR_HUMAN |
|---|---|---|---|---|
| GO:0043169 | cation binding | 35.4839 | 4 | no |
| GO:0046872 | metal ion binding | 35.4839 | 5 | no |
| GO:0000166 | nucleotide binding | 34.4086 | 4 | yes |
| GO:0043168 | anion binding | 34.4086 | 4 | yes |
| GO:0017076 | purine nucleotide binding | 33.3333 | 5 | yes |
| GO:0032555 | purine ribonucleotide binding | 29.0323 | 4 | no |
| GO:0035639 | purine ribonucleoside triphosphate binding | 27.9570 | 4 | no |
| GO:0022890 | inorganic cation transmembrane transporter activity | 22.5806 | 4 | no |
| GO:0016462 | pyrophosphatase activity | 21.5054 | 5 | no |
| GO:0016818 | hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides | 21.5054 | 4 | no |
| GO:0017111 | ribonucleoside triphosphate phosphatase activity | 21.5054 | 6 | no |
| GO:0008324 | monoatomic cation transmembrane transporter activity | 21.5054 | 4 | no |
| GO:0022853 | active monoatomic ion transmembrane transporter activity | 20.4301 | 4 | no |
| GO:0030554 | adenyl nucleotide binding | 16.1290 | 6 | yes |
| GO:0010181 | FMN binding | 3.2258 | 4 | yes |
| GO:0050661 | NADP binding | 3.2258 | 7 | yes |
| GO:0003958 | NADPH-hemoprotein reductase activity | 2.1505 | 5 | yes |
| GO:0016653 | oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor | 2.1505 | 4 | yes |
| GO:0050660 | flavin adenine dinucleotide binding | 2.1505 | 5 | yes |
Biological process
| Term | Name | % | Distance from top the of the tree | Annotated in NCPR_HUMAN |
|---|---|---|---|---|
| GO:0048522 | positive regulation of cellular process | 46.2366 | 4 | no |
| GO:0048523 | negative regulation of cellular process | 35.4839 | 4 | no |
| GO:0010646 | regulation of cell communication | 35.4839 | 4 | no |
| GO:0031323 | regulation of cellular metabolic process | 35.4839 | 4 | no |
| GO:0060255 | regulation of macromolecule metabolic process | 35.4839 | 4 | no |
| GO:0080090 | regulation of primary metabolic process | 33.3333 | 4 | no |
| GO:0051128 | regulation of cellular component organization | 32.2581 | 4 | no |
| GO:0009966 | regulation of signal transduction | 32.2581 | 4 | no |
| GO:0006996 | organelle organization | 29.0323 | 4 | no |
| GO:0022607 | cellular component assembly | 29.0323 | 4 | no |
| GO:0009893 | positive regulation of metabolic process | 29.0323 | 4 | no |
| GO:0051246 | regulation of protein metabolic process | 29.0323 | 5 | no |
| GO:0010604 | positive regulation of macromolecule metabolic process | 27.9570 | 5 | no |
| GO:0008104 | protein localization | 26.8817 | 4 | no |
| GO:0048584 | positive regulation of response to stimulus | 26.8817 | 4 | no |
| GO:0006796 | phosphate-containing compound metabolic process | 25.8065 | 4 | no |
| GO:0071702 | organic substance transport | 24.7312 | 4 | no |
| GO:1902531 | regulation of intracellular signal transduction | 24.7312 | 5 | no |
| GO:0031325 | positive regulation of cellular metabolic process | 24.7312 | 5 | no |
| GO:0042981 | regulation of apoptotic process | 24.7312 | 5 | no |
| GO:0043067 | regulation of programmed cell death | 24.7312 | 4 | no |
| GO:0010647 | positive regulation of cell communication | 23.6559 | 5 | no |
| GO:0023056 | positive regulation of signaling | 23.6559 | 4 | no |
| GO:0009889 | regulation of biosynthetic process | 23.6559 | 4 | no |
| GO:0051049 | regulation of transport | 22.5806 | 4 | no |
| GO:0009967 | positive regulation of signal transduction | 22.5806 | 5 | no |
| GO:0031399 | regulation of protein modification process | 22.5806 | 6 | no |
| GO:0010468 | regulation of gene expression | 22.5806 | 6 | no |
| GO:0010556 | regulation of macromolecule biosynthetic process | 22.5806 | 5 | no |
| GO:0031326 | regulation of cellular biosynthetic process | 22.5806 | 5 | no |
| GO:0042127 | regulation of cell population proliferation | 21.5054 | 4 | no |
| GO:0009892 | negative regulation of metabolic process | 21.5054 | 4 | no |
| GO:0019220 | regulation of phosphate metabolic process | 21.5054 | 6 | no |
| GO:0051174 | regulation of phosphorus metabolic process | 21.5054 | 5 | no |
| GO:0071705 | nitrogen compound transport | 20.4301 | 4 | no |
| GO:0001932 | regulation of protein phosphorylation | 20.4301 | 7 | no |
| GO:0010605 | negative regulation of macromolecule metabolic process | 20.4301 | 5 | no |
| GO:0042325 | regulation of phosphorylation | 20.4301 | 7 | no |
| GO:0051247 | positive regulation of protein metabolic process | 20.4301 | 6 | no |
| GO:0043933 | protein-containing complex organization | 20.4301 | 4 | no |
| GO:0022900 | electron transport chain | 17.2043 | 4 | yes |
| GO:0043085 | positive regulation of catalytic activity | 15.0538 | 4 | yes |
| GO:0051341 | regulation of oxidoreductase activity | 5.3763 | 4 | yes |
| GO:0032768 | regulation of monooxygenase activity | 3.2258 | 5 | yes |
| GO:0032770 | positive regulation of monooxygenase activity | 3.2258 | 6 | yes |
| GO:0051353 | positive regulation of oxidoreductase activity | 3.2258 | 5 | yes |
| GO:0090346 | cellular organofluorine metabolic process | 2.1505 | 4 | yes |
Disease
No data found.
All partners
| Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
|---|---|---|---|---|
| PGRC1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| CYC_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| HMOX1_HUMAN | [view interactions] | Low throughput | no | no |
| FANCC_HUMAN | [view interactions] | Low throughput | no | yes |
| INSI1_HUMAN | [view interactions] | Low throughput | no | no |
| CP2CJ_HUMAN | [view interactions] | Low throughput | no | no |
| CP2C9_HUMAN | [view interactions] | Low throughput | no | no |
| CP2E1_HUMAN | [view interactions] | Low throughput | no | no |
| CP1A2_HUMAN | [view interactions] | Low throughput | no | no |
| NCPR_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| PON2_HUMAN | [view interactions] | High throughput | no | yes |
| NDUA9_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ODBB_HUMAN | [view interactions] | High throughput | no | yes |
| RCN2_HUMAN | [view interactions] | High throughput | no | yes |
| ODPA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| EMC8_HUMAN | [view interactions] | High throughput | no | no |
| HXK1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ADAS_HUMAN | [view interactions] | High throughput | no | yes |
| LACTB_HUMAN | [view interactions] | High throughput | no | yes |
| EFTU_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NDUV2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LTOR2_HUMAN | [view interactions] | High throughput | no | yes |
| EF2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PHB1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CAVN1_HUMAN | [view interactions] | High throughput | no | no |
| COMT_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PHB2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| VATE1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| S2513_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NDUB8_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| A4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NDUA8_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SQOR_HUMAN | [view interactions] | High throughput | no | yes |
| PGES2_HUMAN | [view interactions] | High throughput | no | yes |
| TFR1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CD44_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NB5R3_HUMAN | [view interactions] | High throughput | no | yes |
| COX2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| B2L13_HUMAN | [view interactions] | High throughput | no | no |
| ITB5_HUMAN | [view interactions] | High throughput | no | yes |
| VDAC3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TOM40_HUMAN | [view interactions] | High throughput | no | yes |
| CDIPT_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PAK3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CYB5_HUMAN | [view interactions] | High throughput | no | no |
| CAH9_HUMAN | [view interactions] | High throughput | no | no |
| RHBL4_HUMAN | [view interactions] | High throughput | no | no |
| OTULL_HUMAN | [view interactions] | High throughput | no | no |
| ST7_HUMAN | [view interactions] | High throughput | no | yes |
| PTN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AT2A1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| B3GA1_HUMAN | [view interactions] | High throughput | no | yes |
| CKAP4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DYR2_HUMAN | [view interactions] | High throughput | no | yes |
| ELOV5_HUMAN | [view interactions] | High throughput | no | yes |
| EMD_HUMAN | [view interactions] | High throughput | no | yes |
| CXD3_HUMAN | [view interactions] | High throughput | no | no |
| DHB11_HUMAN | [view interactions] | High throughput | no | yes |
| 3BHS7_HUMAN | [view interactions] | High throughput | no | no |
| LMAN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LNP_HUMAN | [view interactions] | High throughput | no | yes |
| TMT1A_HUMAN | [view interactions] | High throughput | no | no |
| PXMP2_HUMAN | [view interactions] | High throughput | no | no |
| RAB3B_HUMAN | [view interactions] | High throughput | no | no |
| RAB4A_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RAB5A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RAB9A_HUMAN | [view interactions] | High throughput | no | yes |
| REEP5_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SEC62_HUMAN | [view interactions] | High throughput | no | yes |
| SSRA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| STIM1_HUMAN | [view interactions] | High throughput | no | yes |
| STX4_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| LAP2A_HUMAN | [view interactions] | High throughput | no | yes |
| TM11B_HUMAN | [view interactions] | High throughput | no | no |
| CLC4D_HUMAN | [view interactions] | High throughput | no | no |
| TMPS4_HUMAN | [view interactions] | High throughput | no | yes |
| CLC4E_HUMAN | [view interactions] | High throughput | no | no |
| RAB7A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| STING_HUMAN | [view interactions] | High throughput | no | yes |
| ARL1_HUMAN | [view interactions] | High throughput | no | yes |
| GRIA2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KAP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CCNF_HUMAN | [view interactions] | High throughput | no | no |
| RAB18_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ESYT1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ESYT2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PA24A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| STAT1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RABEK_HUMAN | [view interactions] | High throughput | no | yes |
| SYRC_HUMAN | [view interactions] | High throughput | no | yes |
| SNX8_HUMAN | [view interactions] | High throughput | no | yes |
| CAV2_HUMAN | [view interactions] | High throughput | no | no |
| PEBP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ZDHC5_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RMC1_HUMAN | [view interactions] | High throughput | no | no |
| NPC1_HUMAN | [view interactions] | High throughput | no | yes |
| SYVN1_HUMAN | [view interactions] | High throughput | no | yes |
| DERL1_HUMAN | [view interactions] | High throughput | no | yes |
| DERL2_HUMAN | [view interactions] | High throughput | no | yes |
| INSR_HUMAN | [view interactions] | High throughput | no | yes |
| XRCC6_HUMAN | [view interactions] | High throughput | no | yes |
| TECT3_HUMAN | [view interactions] | High throughput | no | yes |
| LBN_HUMAN | [view interactions] | High throughput | no | yes |
| TECT2_HUMAN | [view interactions] | High throughput | no | yes |
| TM216_HUMAN | [view interactions] | High throughput | no | no |
| RASK_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RASN_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RASH_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CNEP1_HUMAN | [view interactions] | High throughput | no | yes |
| CFTR_HUMAN | [view interactions] | High throughput | no | no |
| KCNK3_HUMAN | [view interactions] | High throughput | no | no |
| UBC_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SRPRB_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| BT2A1_HUMAN | [view interactions] | High throughput | no | yes |
| UBXN6_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NTRK1_HUMAN | [view interactions] | High throughput | no | yes |
| ZN598_HUMAN | [view interactions] | High throughput | no | no |
| RNF4_HUMAN | [view interactions] | High throughput | no | yes |
| VIR_HUMAN | [view interactions] | High throughput | no | yes |
| UBQL2_HUMAN | [view interactions] | High throughput | no | yes |
| APEX1_HUMAN | [view interactions] | High throughput | no | yes |
| BIRC3_HUMAN | [view interactions] | High throughput | no | no |
| LMBRL_HUMAN | [view interactions] | High throughput | no | no |
| EMC1_HUMAN | [view interactions] | High throughput | no | yes |
| EMC2_HUMAN | [view interactions] | High throughput | no | yes |
| EMC4_HUMAN | [view interactions] | High throughput | no | yes |
| CTRO_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ANLN_HUMAN | [view interactions] | High throughput | no | yes |
| CHM4C_HUMAN | [view interactions] | High throughput | no | yes |
| ECT2_HUMAN | [view interactions] | High throughput | no | no |
| KIF14_HUMAN | [view interactions] | High throughput | no | no |
| KIF23_HUMAN | [view interactions] | High throughput | no | yes |
| PRC1_HUMAN | [view interactions] | High throughput | no | yes |
| CFAD_HUMAN | [view interactions] | High throughput | no | no |
| FNDC5_HUMAN | [view interactions] | High throughput | no | no |
| DJC25_HUMAN | [view interactions] | High throughput | no | yes |
| FA20C_HUMAN | [view interactions] | High throughput | no | no |
| RIGI_HUMAN | [view interactions] | High throughput | no | yes |
| ISG15_HUMAN | [view interactions] | High throughput | no | no |
| MATN1_HUMAN | [view interactions] | High throughput | no | no |
| FGF12_HUMAN | [view interactions] | High throughput | no | no |
| PIGH_HUMAN | [view interactions] | High throughput | no | yes |
| PINK1_HUMAN | [view interactions] | High throughput | no | yes |
| SSUH2_HUMAN | [view interactions] | High throughput | no | no |
| CD63_HUMAN | [view interactions] | High throughput | no | no |
| CCR1_HUMAN | [view interactions] | High throughput | no | no |
| NTNG1_HUMAN | [view interactions] | High throughput | no | no |
| NRP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GCR_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RHOA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CDC42_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RHOG_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RAC2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RAC3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RHOC_HUMAN | [view interactions] | High throughput | no | no |
| RHOD_HUMAN | [view interactions] | High throughput | no | no |
| RHOF_HUMAN | [view interactions] | High throughput | no | no |
| RHOH_HUMAN | [view interactions] | High throughput | no | yes |
| RND2_HUMAN | [view interactions] | High throughput | no | no |
| RAC1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| BAP31_HUMAN | [view interactions] | High throughput | no | yes |
| CALX_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CLAP2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| DAD1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| OST48_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FKBP8_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KTAP2_HUMAN | [view interactions] | High throughput | no | no |
| OST4_HUMAN | [view interactions] | High throughput | no | no |
| PGRC2_HUMAN | [view interactions] | High throughput | no | yes |
| RPN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RPN2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RTN4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SC61B_HUMAN | [view interactions] | High throughput | no | yes |
| SRPRA_HUMAN | [view interactions] | High throughput | no | no |
| STT3B_HUMAN | [view interactions] | High throughput | no | yes |
| TMEDA_HUMAN | [view interactions] | High throughput | no | yes |
| VAPA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| F241A_HUMAN | [view interactions] | High throughput | no | yes |
| CCD47_HUMAN | [view interactions] | High throughput | no | yes |
| TERA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PRKN_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CUL3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ZRAN1_HUMAN | [view interactions] | High throughput | no | yes |
| PAQR2_HUMAN | [view interactions] | High throughput | no | yes |
| TRI67_HUMAN | [view interactions] | High throughput | no | no |
| MOB3C_HUMAN | [view interactions] | High throughput | no | no |
| PRIO_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SPOP_HUMAN | [view interactions] | High throughput | no | no |
| GOLI_HUMAN | [view interactions] | High throughput | no | yes |
| RN149_HUMAN | [view interactions] | High throughput | no | no |
| SC6A8_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| SPPL3_HUMAN | [view interactions] | High throughput | no | no |
| CP2A6_HUMAN | [view interactions] | High throughput | no | no |
| CP2D6_HUMAN | [view interactions] | High throughput | no | no |
| CP3A4_HUMAN | [view interactions] | High throughput | no | no |
| ATLA3_HUMAN | [view interactions] | High throughput | no | no |
| NDUB9_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NDUV1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SYDM_HUMAN | [view interactions] | High throughput | no | yes |
| EWS_HUMAN | [view interactions] | High throughput | no | yes |
| PLOD1_HUMAN | [view interactions] | High throughput | no | yes |
| PLOD3_HUMAN | [view interactions] | High throughput | no | yes |
| XPO1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NNTM_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| P4HA1_HUMAN | [view interactions] | High throughput | no | yes |
| QCR1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NDUS3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NDUS1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| VATB2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LRC59_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LONM_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ASPH_HUMAN | [view interactions] | High throughput | no | yes |
| LPPRC_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| QCR2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NDUS7_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| NDUS8_HUMAN | [view interactions] | High throughput | no | yes |
| COR1C_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| VATA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HMOX2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CY1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ARMX3_HUMAN | [view interactions] | High throughput | no | no |
| QCR6_HUMAN | [view interactions] | High throughput | no | yes |
| AT2A2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ODBA_HUMAN | [view interactions] | High throughput | no | yes |
| APOE_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TPP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ATPB_HUMAN | [view interactions] | High throughput | no | yes |
| ODPB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |