CDIPT_HUMAN
Evidence for PS localization
Functions
Catalyzes the biosynthesis of phosphatidylinositol (PtdIns) as well as PtdIns:inositol exchange reaction. May thus act to reduce an excessive cellular PtdIns content. The exchange activity is due to the reverse reaction of PtdIns synthase and is dependent on CMP, which is tightly bound to the enzyme. [View more on UniProt]
Protein features
Binary interactions with known binding regions
Interacting region for partners were not defined.
Network
Isoforms
Disease-causing germline mutations
No data found.
Linear motifs
No annotated instance was found. To search for linear motifs, use the ELM prediction server.
Fingerprint
Molecular function
| Term | Name | % | Distance from the top of the tree | Annotated in CDIPT_HUMAN |
|---|---|---|---|---|
| GO:0017076 | purine nucleotide binding | 22.8571 | 4 | no |
| GO:0032555 | purine ribonucleotide binding | 22.8571 | 4 | no |
| GO:0046872 | metal ion binding | 17.1429 | 4 | yes |
| GO:0046914 | transition metal ion binding | 14.2857 | 5 | yes |
| GO:0030145 | manganese ion binding | 5.7143 | 6 | yes |
Biological process
| Term | Name | % | Distance from top the of the tree | Annotated in CDIPT_HUMAN |
|---|---|---|---|---|
| GO:0048522 | positive regulation of cellular process | 57.1429 | 4 | no |
| GO:0010646 | regulation of cell communication | 54.2857 | 4 | no |
| GO:0048523 | negative regulation of cellular process | 54.2857 | 4 | no |
| GO:0060255 | regulation of macromolecule metabolic process | 54.2857 | 4 | no |
| GO:0009966 | regulation of signal transduction | 51.4286 | 4 | no |
| GO:0080090 | regulation of primary metabolic process | 51.4286 | 4 | no |
| GO:0031323 | regulation of cellular metabolic process | 48.5714 | 4 | no |
| GO:0051128 | regulation of cellular component organization | 45.7143 | 4 | no |
| GO:0051171 | regulation of nitrogen compound metabolic process | 45.7143 | 4 | no |
| GO:0009892 | negative regulation of metabolic process | 40.0000 | 4 | no |
| GO:0010605 | negative regulation of macromolecule metabolic process | 40.0000 | 5 | no |
| GO:0051246 | regulation of protein metabolic process | 40.0000 | 5 | no |
| GO:0009893 | positive regulation of metabolic process | 37.1429 | 4 | no |
| GO:0010468 | regulation of gene expression | 37.1429 | 5 | no |
| GO:0031324 | negative regulation of cellular metabolic process | 37.1429 | 5 | no |
| GO:0051172 | negative regulation of nitrogen compound metabolic process | 37.1429 | 5 | no |
| GO:1902531 | regulation of intracellular signal transduction | 37.1429 | 5 | no |
| GO:0006996 | organelle organization | 34.2857 | 4 | no |
| GO:0010604 | positive regulation of macromolecule metabolic process | 34.2857 | 5 | no |
| GO:0010647 | positive regulation of cell communication | 34.2857 | 5 | no |
| GO:0023056 | positive regulation of signaling | 34.2857 | 4 | no |
| GO:0019220 | regulation of phosphate metabolic process | 31.4286 | 6 | no |
| GO:0048584 | positive regulation of response to stimulus | 31.4286 | 4 | no |
| GO:0051174 | regulation of phosphorus metabolic process | 31.4286 | 5 | no |
| GO:0071310 | cellular response to organic substance | 31.4286 | 4 | no |
| GO:0006796 | phosphate-containing compound metabolic process | 28.5714 | 4 | yes |
| GO:0009889 | regulation of biosynthetic process | 28.5714 | 4 | no |
| GO:0009967 | positive regulation of signal transduction | 28.5714 | 5 | no |
| GO:0031325 | positive regulation of cellular metabolic process | 28.5714 | 5 | no |
| GO:0031326 | regulation of cellular biosynthetic process | 28.5714 | 5 | no |
| GO:0031399 | regulation of protein modification process | 28.5714 | 6 | no |
| GO:0042325 | regulation of phosphorylation | 28.5714 | 7 | no |
| GO:0051173 | positive regulation of nitrogen compound metabolic process | 28.5714 | 5 | no |
| GO:0051248 | negative regulation of protein metabolic process | 28.5714 | 6 | no |
| GO:0051049 | regulation of transport | 28.5714 | 4 | no |
| GO:0001932 | regulation of protein phosphorylation | 25.7143 | 7 | no |
| GO:0010556 | regulation of macromolecule biosynthetic process | 25.7143 | 5 | no |
| GO:0010648 | negative regulation of cell communication | 25.7143 | 5 | no |
| GO:0023057 | negative regulation of signaling | 25.7143 | 4 | no |
| GO:0036211 | protein modification process | 25.7143 | 4 | no |
| GO:0042127 | regulation of cell population proliferation | 25.7143 | 4 | no |
| GO:0043085 | positive regulation of catalytic activity | 25.7143 | 4 | no |
| GO:0043412 | macromolecule modification | 25.7143 | 4 | no |
| GO:0051247 | positive regulation of protein metabolic process | 25.7143 | 6 | no |
| GO:0051336 | regulation of hydrolase activity | 25.7143 | 4 | no |
| GO:0022607 | cellular component assembly | 25.7143 | 4 | no |
| GO:0033043 | regulation of organelle organization | 25.7143 | 5 | no |
| GO:0044087 | regulation of cellular component biogenesis | 25.7143 | 4 | no |
| GO:0050804 | modulation of chemical synaptic transmission | 25.7143 | 5 | no |
| GO:0099177 | regulation of trans-synaptic signaling | 25.7143 | 4 | no |
| GO:1901701 | cellular response to oxygen-containing compound | 25.7143 | 4 | no |
| GO:0008610 | lipid biosynthetic process | 22.8571 | 4 | yes |
| GO:0006355 | regulation of DNA-templated transcription | 22.8571 | 6 | no |
| GO:0009968 | negative regulation of signal transduction | 22.8571 | 5 | no |
| GO:0010941 | regulation of cell death | 22.8571 | 4 | no |
| GO:0019219 | regulation of nucleobase-containing compound metabolic process | 22.8571 | 5 | no |
| GO:0043408 | regulation of MAPK cascade | 22.8571 | 6 | no |
| GO:0048585 | negative regulation of response to stimulus | 22.8571 | 4 | no |
| GO:0051252 | regulation of RNA metabolic process | 22.8571 | 5 | no |
| GO:1902533 | positive regulation of intracellular signal transduction | 22.8571 | 6 | no |
| GO:1903506 | regulation of nucleic acid-templated transcription | 22.8571 | 7 | no |
| GO:2001141 | regulation of RNA biosynthetic process | 22.8571 | 6 | no |
| GO:0030030 | cell projection organization | 22.8571 | 4 | no |
| GO:0045595 | regulation of cell differentiation | 22.8571 | 4 | no |
| GO:0120036 | plasma membrane bounded cell projection organization | 22.8571 | 5 | no |
| GO:0008104 | protein localization | 22.8571 | 4 | no |
| GO:0030334 | regulation of cell migration | 22.8571 | 5 | no |
| GO:2000145 | regulation of cell motility | 22.8571 | 4 | no |
| GO:0006644 | phospholipid metabolic process | 20.0000 | 4 | yes |
| GO:0006650 | glycerophospholipid metabolic process | 20.0000 | 5 | yes |
| GO:0006661 | phosphatidylinositol biosynthetic process | 20.0000 | 6 | yes |
| GO:0008654 | phospholipid biosynthetic process | 20.0000 | 4 | yes |
| GO:0045017 | glycerolipid biosynthetic process | 20.0000 | 4 | yes |
| GO:0046474 | glycerophospholipid biosynthetic process | 20.0000 | 5 | yes |
| GO:0046486 | glycerolipid metabolic process | 20.0000 | 4 | yes |
| GO:0046488 | phosphatidylinositol metabolic process | 20.0000 | 6 | yes |
| GO:0090407 | organophosphate biosynthetic process | 20.0000 | 4 | yes |
Disease
No data found.
All partners
| Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
|---|---|---|---|---|
| YTHD1_HUMAN | [view interactions] | High throughput | no | no |
| DCC1_HUMAN | [view interactions] | High throughput | no | yes |
| CYFP2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ECH1_HUMAN | [view interactions] | High throughput | no | yes |
| ST32C_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SG196_HUMAN | [view interactions] | High throughput | no | yes |
| NTRK1_HUMAN | [view interactions] | High throughput | no | yes |
| NTRK3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HSC20_HUMAN | [view interactions] | High throughput | no | yes |
| SDCB1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RTN3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LNX1_HUMAN | [view interactions] | High throughput | no | yes |
| M4A14_HUMAN | [view interactions] | High throughput | no | no |
| JAGN1_HUMAN | [view interactions] | High throughput | no | no |
| AQP6_HUMAN | [view interactions] | High throughput | no | no |
| RETR3_HUMAN | [view interactions] | High throughput | no | yes |
| GPX8_HUMAN | [view interactions] | High throughput | no | no |
| DHB13_HUMAN | [view interactions] | High throughput | no | yes |
| MGST3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NB5R3_HUMAN | [view interactions] | High throughput | no | yes |
| TMX2_HUMAN | [view interactions] | High throughput | no | yes |
| IR3IP_HUMAN | [view interactions] | High throughput | no | yes |
| FFAR2_HUMAN | [view interactions] | High throughput | no | yes |
| GP101_HUMAN | [view interactions] | High throughput | no | no |
| VMA21_HUMAN | [view interactions] | High throughput | no | no |
| SIG12_HUMAN | [view interactions] | High throughput | no | no |
| F209A_HUMAN | [view interactions] | High throughput | no | no |
| RN19B_HUMAN | [view interactions] | High throughput | no | yes |
| ERGI3_HUMAN | [view interactions] | High throughput | no | yes |
| AQP2_HUMAN | [view interactions] | High throughput | no | no |
| SL7A1_HUMAN | [view interactions] | High throughput | no | no |
| CY561_HUMAN | [view interactions] | High throughput | no | yes |
| CISD2_HUMAN | [view interactions] | High throughput | no | yes |
| KCNK1_HUMAN | [view interactions] | High throughput | no | yes |
| IBP6_HUMAN | [view interactions] | High throughput | no | yes |
| CGRF1_HUMAN | [view interactions] | High throughput | no | yes |
| SCAI_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KI2L3_HUMAN | [view interactions] | High throughput | no | no |
| CXB1_HUMAN | [view interactions] | High throughput | no | yes |
| RELL2_HUMAN | [view interactions] | High throughput | no | no |
| TLCD4_HUMAN | [view interactions] | High throughput | no | no |
| MOT2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| IF3M_HUMAN | [view interactions] | High throughput | no | yes |
| GOLM1_HUMAN | [view interactions] | High throughput | no | yes |
| GP152_HUMAN | [view interactions] | High throughput | no | no |
| CD79A_HUMAN | [view interactions] | High throughput | no | no |
| EBP_HUMAN | [view interactions] | High throughput | no | no |
| SOAT_HUMAN | [view interactions] | High throughput | no | no |
| SYDM_HUMAN | [view interactions] | High throughput | no | yes |
| VA0E1_HUMAN | [view interactions] | High throughput | no | no |
| AR13B_HUMAN | [view interactions] | High throughput | no | yes |
| FKBP7_HUMAN | [view interactions] | High throughput | no | yes |
| ODFP4_HUMAN | [view interactions] | High throughput | no | no |
| CPLX4_HUMAN | [view interactions] | High throughput | no | no |
| GP151_HUMAN | [view interactions] | High throughput | no | no |
| BSND_HUMAN | [view interactions] | High throughput | no | no |
| TNR1A_HUMAN | [view interactions] | High throughput | no | yes |
| TNR1B_HUMAN | [view interactions] | High throughput | no | no |
| ILK_HUMAN | [view interactions] | High throughput | no | no |
| HIPK4_HUMAN | [view interactions] | High throughput | no | no |
| DYRK4_HUMAN | [view interactions] | High throughput | no | no |
| UN93A_HUMAN | [view interactions] | High throughput | no | no |
| MYPR_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FCG2A_HUMAN | [view interactions] | High throughput | no | no |
| FCERG_HUMAN | [view interactions] | High throughput | no | no |
| MFF_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| EVI2B_HUMAN | [view interactions] | High throughput | no | no |
| KI2S2_HUMAN | [view interactions] | High throughput | no | no |
| NOS2_HUMAN | [view interactions] | High throughput | no | yes |
| UBL4A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MMS19_HUMAN | [view interactions] | High throughput | no | yes |
| CLN5_HUMAN | [view interactions] | High throughput | no | yes |
| EGFR_HUMAN | [view interactions] | High throughput | no | no |
| STAU1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PCSK9_HUMAN | [view interactions] | High throughput | no | no |
| EED_HUMAN | [view interactions] | High throughput | no | yes |
| PTN1_HUMAN | [view interactions] | High throughput | no | yes |
| PTN18_HUMAN | [view interactions] | High throughput | no | yes |
| SMAP2_HUMAN | [view interactions] | High throughput | no | yes |
| UQCC1_HUMAN | [view interactions] | High throughput | no | yes |
| FACD2_HUMAN | [view interactions] | High throughput | no | no |
| RNF4_HUMAN | [view interactions] | High throughput | no | yes |
| ESR2_HUMAN | [view interactions] | High throughput | no | no |
| RN123_HUMAN | [view interactions] | High throughput | no | yes |
| WWOX_HUMAN | [view interactions] | High throughput | no | yes |
| GRWD1_HUMAN | [view interactions] | High throughput | no | no |
| CTDP1_HUMAN | [view interactions] | High throughput | no | yes |
| PHB1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MD2L2_HUMAN | [view interactions] | High throughput | no | yes |
| TAU_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DUS7_HUMAN | [view interactions] | High throughput | no | yes |
| SSH1_HUMAN | [view interactions] | High throughput | no | yes |
| LMBRL_HUMAN | [view interactions] | High throughput | no | no |
| RGS14_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CIC_HUMAN | [view interactions] | High throughput | no | yes |
| CSN5_HUMAN | [view interactions] | High throughput | no | yes |
| CFAD_HUMAN | [view interactions] | High throughput | no | no |
| FNDC5_HUMAN | [view interactions] | High throughput | no | no |
| DDRGK_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| P53_HUMAN | [view interactions] | High throughput | no | no |
| WDR5_HUMAN | [view interactions] | High throughput | no | no |
| GP173_HUMAN | [view interactions] | High throughput | no | no |
| NAAA_HUMAN | [view interactions] | High throughput | no | yes |
| GPR45_HUMAN | [view interactions] | High throughput | no | no |
| EVA1C_HUMAN | [view interactions] | High throughput | no | yes |
| NNRD_HUMAN | [view interactions] | High throughput | no | yes |
| HYAL1_HUMAN | [view interactions] | High throughput | no | no |
| T170A_HUMAN | [view interactions] | High throughput | no | no |
| FFAR1_HUMAN | [view interactions] | High throughput | no | no |
| SPRTN_HUMAN | [view interactions] | High throughput | no | yes |
| CATL1_HUMAN | [view interactions] | High throughput | no | yes |
| DPP4_HUMAN | [view interactions] | High throughput | no | no |
| IFM3_HUMAN | [view interactions] | High throughput | no | yes |
| TM11B_HUMAN | [view interactions] | High throughput | no | no |
| TMPS4_HUMAN | [view interactions] | High throughput | no | yes |
| PDE2A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NEB2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GPAT4_HUMAN | [view interactions] | High throughput | no | yes |
| RASK_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RIT1_HUMAN | [view interactions] | High throughput | no | yes |
| A4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PCNA_HUMAN | [view interactions] | High throughput | no | no |
| NCPR_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RAP1B_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| EXD2_HUMAN | [view interactions] | High throughput | no | yes |
| LEG9_HUMAN | [view interactions] | High throughput | no | yes |
| GCR_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ARF6_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CK052_HUMAN | [view interactions] | High throughput | no | no |
| RPA34_HUMAN | [view interactions] | High throughput | no | yes |
| COIL_HUMAN | [view interactions] | High throughput | no | yes |
| CXD3_HUMAN | [view interactions] | High throughput | no | no |
| 3BHS7_HUMAN | [view interactions] | High throughput | no | no |
| LTOR1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LNP_HUMAN | [view interactions] | High throughput | no | yes |
| NU155_HUMAN | [view interactions] | High throughput | no | yes |
| PANX1_HUMAN | [view interactions] | High throughput | no | no |
| PEX3_HUMAN | [view interactions] | High throughput | no | yes |
| RPA49_HUMAN | [view interactions] | High throughput | no | yes |
| RAB5C_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| BROMI_HUMAN | [view interactions] | High throughput | no | no |
| RLA1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| GLUT4_HUMAN | [view interactions] | High throughput | no | no |
| AGO4_HUMAN | [view interactions] | High throughput | no | no |
| IQCB1_HUMAN | [view interactions] | High throughput | no | no |
| NLRX1_HUMAN | [view interactions] | High throughput | no | yes |
| UN93B_HUMAN | [view interactions] | High throughput | no | yes |
| SARM1_HUMAN | [view interactions] | High throughput | no | yes |
| MK06_HUMAN | [view interactions] | High throughput | no | yes |
| RIPK4_HUMAN | [view interactions] | High throughput | no | no |
| CAZA2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ORC1_HUMAN | [view interactions] | High throughput | no | yes |
| SAMD1_HUMAN | [view interactions] | High throughput | no | no |
| TTC5_HUMAN | [view interactions] | High throughput | no | yes |
| PTEN_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| PIGQ_HUMAN | [view interactions] | Computational | no | yes |
| PIGY_HUMAN | [view interactions] | Computational | no | no |
| MTMR8_HUMAN | [view interactions] | Computational | no | no |
| PIGA_HUMAN | [view interactions] | Computational | no | yes |
| PISD_HUMAN | [view interactions] | Computational | no | yes |
| INO1_HUMAN | [view interactions] | Computational | no | no |
| CDS1_HUMAN | [view interactions] | Computational | no | yes |
| ASPH1_HUMAN | [view interactions] | Computational | no | yes |
| P4K2A_HUMAN | [view interactions] | Computational | no | yes |
| PI4KA_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| P3C2A_HUMAN | [view interactions] | Computational | no | yes |
| MTMR4_HUMAN | [view interactions] | Computational | no | no |
| PIGH_HUMAN | [view interactions] | Computational | no | yes |
| MTMRE_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| IMPA1_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| IMPA3_HUMAN | [view interactions] | Computational | no | yes |
| FYV1_HUMAN | [view interactions] | Computational | no | no |
| MIOX_HUMAN | [view interactions] | Computational | no | no |
| SAC1_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| MTMR1_HUMAN | [view interactions] | Computational | no | yes |
| P85B_HUMAN | [view interactions] | Computational | no | yes |
| PGPS1_HUMAN | [view interactions] | Computational | no | yes |
| P3C2B_HUMAN | [view interactions] | Computational | no | no |
| IMPA2_HUMAN | [view interactions] | Computational | no | no |
| P85A_HUMAN | [view interactions] | Computational | no | yes |
| MTM1_HUMAN | [view interactions] | Computational | no | yes |
| PIGC_HUMAN | [view interactions] | Computational | no | no |
| PK3CG_HUMAN | [view interactions] | Computational | no | yes |
| P4K2B_HUMAN | [view interactions] | Computational | no | yes |
| MTMR7_HUMAN | [view interactions] | Computational | no | no |
| DPM2_HUMAN | [view interactions] | Computational | no | yes |
| PK3C3_HUMAN | [view interactions] | Computational | no | yes |
| MTMR3_HUMAN | [view interactions] | Computational | no | no |
| TAM41_HUMAN | [view interactions] | Computational | no | no |
| MTMR6_HUMAN | [view interactions] | Computational | no | no |
| PIGP_HUMAN | [view interactions] | Computational | no | yes |
| PI3R4_HUMAN | [view interactions] | Computational | no | yes |
| CRLS1_HUMAN | [view interactions] | Computational | no | no |
| MTMR2_HUMAN | [view entry] [view interactions] | Computational | yes | no |
| P55G_HUMAN | [view interactions] | Computational | no | yes |
| CDS2_HUMAN | [view interactions] | Computational | no | yes |