CDIPT_HUMAN
Evidence for PS localization
Functions
Catalyzes the biosynthesis of phosphatidylinositol (PtdIns) as well as PtdIns:inositol exchange reaction. May thus act to reduce an excessive cellular PtdIns content. The exchange activity is due to the reverse reaction of PtdIns synthase and is dependent on CMP, which is tightly bound to the enzyme. [View more on UniProt]
Protein features
Binary interactions with known binding regions
Interacting region for partners were not defined.
Network
Isoforms
Disease-causing germline mutations
No data found.
Linear motifs
No annotated instance was found. To search for linear motifs, use the ELM prediction server.
Fingerprint
Molecular function
| Term | Name | % | Distance from the top of the tree | Annotated in CDIPT_HUMAN |
|---|---|---|---|---|
| GO:0043168 | anion binding | 25.7143 | 4 | no |
| GO:0000166 | nucleotide binding | 22.8571 | 4 | no |
| GO:0017076 | purine nucleotide binding | 22.8571 | 5 | no |
| GO:0043169 | cation binding | 20.0000 | 4 | yes |
| GO:0046872 | metal ion binding | 20.0000 | 5 | yes |
Biological process
| Term | Name | % | Distance from top the of the tree | Annotated in CDIPT_HUMAN |
|---|---|---|---|---|
| GO:0048522 | positive regulation of cellular process | 57.1429 | 4 | no |
| GO:0010646 | regulation of cell communication | 54.2857 | 4 | no |
| GO:0048523 | negative regulation of cellular process | 54.2857 | 4 | no |
| GO:0009966 | regulation of signal transduction | 51.4286 | 4 | no |
| GO:0060255 | regulation of macromolecule metabolic process | 48.5714 | 4 | no |
| GO:0051128 | regulation of cellular component organization | 42.8571 | 4 | no |
| GO:1902531 | regulation of intracellular signal transduction | 40.0000 | 5 | no |
| GO:0031323 | regulation of cellular metabolic process | 40.0000 | 4 | no |
| GO:0080090 | regulation of primary metabolic process | 40.0000 | 4 | no |
| GO:0010647 | positive regulation of cell communication | 34.2857 | 5 | no |
| GO:0023056 | positive regulation of signaling | 34.2857 | 4 | no |
| GO:0006996 | organelle organization | 34.2857 | 4 | no |
| GO:0009892 | negative regulation of metabolic process | 34.2857 | 4 | no |
| GO:0010605 | negative regulation of macromolecule metabolic process | 34.2857 | 5 | no |
| GO:0009893 | positive regulation of metabolic process | 34.2857 | 4 | no |
| GO:0048584 | positive regulation of response to stimulus | 31.4286 | 4 | no |
| GO:0031324 | negative regulation of cellular metabolic process | 31.4286 | 5 | no |
| GO:0051246 | regulation of protein metabolic process | 31.4286 | 5 | no |
| GO:0009889 | regulation of biosynthetic process | 31.4286 | 4 | no |
| GO:0010468 | regulation of gene expression | 31.4286 | 6 | no |
| GO:0010556 | regulation of macromolecule biosynthetic process | 31.4286 | 5 | no |
| GO:0010604 | positive regulation of macromolecule metabolic process | 31.4286 | 5 | no |
| GO:0031325 | positive regulation of cellular metabolic process | 31.4286 | 5 | no |
| GO:0031326 | regulation of cellular biosynthetic process | 31.4286 | 5 | no |
| GO:0009967 | positive regulation of signal transduction | 28.5714 | 5 | no |
| GO:0019220 | regulation of phosphate metabolic process | 28.5714 | 6 | no |
| GO:0042325 | regulation of phosphorylation | 28.5714 | 7 | no |
| GO:0051174 | regulation of phosphorus metabolic process | 28.5714 | 5 | no |
| GO:0008104 | protein localization | 28.5714 | 4 | no |
| GO:1902533 | positive regulation of intracellular signal transduction | 25.7143 | 6 | no |
| GO:0031399 | regulation of protein modification process | 25.7143 | 6 | no |
| GO:0043408 | regulation of MAPK cascade | 22.8571 | 6 | no |
| GO:0051049 | regulation of transport | 22.8571 | 4 | no |
| GO:0010648 | negative regulation of cell communication | 22.8571 | 5 | no |
| GO:0023057 | negative regulation of signaling | 22.8571 | 4 | no |
| GO:0001932 | regulation of protein phosphorylation | 22.8571 | 7 | no |
| GO:0009890 | negative regulation of biosynthetic process | 22.8571 | 5 | no |
| GO:0009891 | positive regulation of biosynthetic process | 22.8571 | 5 | no |
| GO:0010557 | positive regulation of macromolecule biosynthetic process | 22.8571 | 6 | no |
| GO:0010558 | negative regulation of macromolecule biosynthetic process | 22.8571 | 6 | no |
| GO:0010562 | positive regulation of phosphorus metabolic process | 22.8571 | 6 | no |
| GO:0031327 | negative regulation of cellular biosynthetic process | 22.8571 | 6 | no |
| GO:0031328 | positive regulation of cellular biosynthetic process | 22.8571 | 6 | no |
| GO:0042327 | positive regulation of phosphorylation | 22.8571 | 8 | no |
| GO:0045937 | positive regulation of phosphate metabolic process | 22.8571 | 7 | no |
| GO:0051247 | positive regulation of protein metabolic process | 22.8571 | 6 | no |
| GO:0022607 | cellular component assembly | 22.8571 | 4 | no |
| GO:0006796 | phosphate-containing compound metabolic process | 20.0000 | 4 | yes |
| GO:0008610 | lipid biosynthetic process | 5.7143 | 4 | yes |
Disease
No data found.
All partners
| Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
|---|---|---|---|---|
| EED_HUMAN | [view interactions] | High throughput | no | yes |
| PTN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PTN18_HUMAN | [view interactions] | High throughput | no | yes |
| SMAP2_HUMAN | [view interactions] | High throughput | no | yes |
| UQCC1_HUMAN | [view interactions] | High throughput | no | yes |
| FACD2_HUMAN | [view interactions] | High throughput | no | no |
| RNF4_HUMAN | [view interactions] | High throughput | no | yes |
| ESR2_HUMAN | [view interactions] | High throughput | no | no |
| RN123_HUMAN | [view interactions] | High throughput | no | yes |
| WWOX_HUMAN | [view interactions] | High throughput | no | yes |
| GRWD1_HUMAN | [view interactions] | High throughput | no | no |
| PHB1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MD2L2_HUMAN | [view interactions] | High throughput | no | yes |
| TAU_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DUS7_HUMAN | [view interactions] | High throughput | no | yes |
| SSH1_HUMAN | [view interactions] | High throughput | no | yes |
| LMBRL_HUMAN | [view interactions] | High throughput | no | no |
| RGS14_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CIC_HUMAN | [view interactions] | High throughput | no | yes |
| CSN5_HUMAN | [view interactions] | High throughput | no | yes |
| CFAD_HUMAN | [view interactions] | High throughput | no | no |
| FNDC5_HUMAN | [view interactions] | High throughput | no | no |
| DDRGK_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| P53_HUMAN | [view interactions] | High throughput | no | no |
| WDR5_HUMAN | [view interactions] | High throughput | no | no |
| GP173_HUMAN | [view interactions] | High throughput | no | no |
| NAAA_HUMAN | [view interactions] | High throughput | no | yes |
| GPR45_HUMAN | [view interactions] | High throughput | no | no |
| EVA1C_HUMAN | [view interactions] | High throughput | no | yes |
| NNRD_HUMAN | [view interactions] | High throughput | no | yes |
| HYAL1_HUMAN | [view interactions] | High throughput | no | no |
| T170A_HUMAN | [view interactions] | High throughput | no | no |
| FFAR1_HUMAN | [view interactions] | High throughput | no | no |
| SPRTN_HUMAN | [view interactions] | High throughput | no | yes |
| CATL1_HUMAN | [view interactions] | High throughput | no | yes |
| DPP4_HUMAN | [view interactions] | High throughput | no | no |
| IFM3_HUMAN | [view interactions] | High throughput | no | yes |
| TM11B_HUMAN | [view interactions] | High throughput | no | no |
| TMPS4_HUMAN | [view interactions] | High throughput | no | yes |
| PDE2A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NEB2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GPAT4_HUMAN | [view interactions] | High throughput | no | yes |
| CCNF_HUMAN | [view interactions] | High throughput | no | no |
| TRI67_HUMAN | [view interactions] | High throughput | no | no |
| EZH2_HUMAN | [view interactions] | High throughput | no | no |
| CL16A_HUMAN | [view interactions] | High throughput | no | yes |
| RN149_HUMAN | [view interactions] | High throughput | no | no |
| GRM2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| UBE2H_HUMAN | [view interactions] | High throughput | no | yes |
| RASK_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RIT1_HUMAN | [view interactions] | High throughput | no | yes |
| A4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PCNA_HUMAN | [view interactions] | High throughput | no | no |
| NCPR_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RAP1B_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| EXD2_HUMAN | [view interactions] | High throughput | no | yes |
| LEG9_HUMAN | [view interactions] | High throughput | no | yes |
| GCR_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ARF6_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CK052_HUMAN | [view interactions] | High throughput | no | no |
| RPA34_HUMAN | [view interactions] | High throughput | no | yes |
| COIL_HUMAN | [view interactions] | High throughput | no | yes |
| CXD3_HUMAN | [view interactions] | High throughput | no | no |
| 3BHS7_HUMAN | [view interactions] | High throughput | no | no |
| LTOR1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LNP_HUMAN | [view interactions] | High throughput | no | yes |
| NU155_HUMAN | [view interactions] | High throughput | no | yes |
| PANX1_HUMAN | [view interactions] | High throughput | no | no |
| PEX3_HUMAN | [view interactions] | High throughput | no | yes |
| RPA49_HUMAN | [view interactions] | High throughput | no | yes |
| RAB5C_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| BROMI_HUMAN | [view interactions] | High throughput | no | no |
| ATG9A_HUMAN | [view interactions] | High throughput | no | yes |
| CLPP_HUMAN | [view interactions] | High throughput | no | yes |
| STING_HUMAN | [view interactions] | High throughput | no | yes |
| TGON2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RFA1_HUMAN | [view interactions] | High throughput | no | yes |
| RFA2_HUMAN | [view interactions] | High throughput | no | yes |
| RFA3_HUMAN | [view interactions] | High throughput | no | yes |
| RLA1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| GLUT4_HUMAN | [view interactions] | High throughput | no | no |
| AGO4_HUMAN | [view interactions] | High throughput | no | no |
| IQCB1_HUMAN | [view interactions] | High throughput | no | no |
| NLRX1_HUMAN | [view interactions] | High throughput | no | yes |
| UN93B_HUMAN | [view interactions] | High throughput | no | yes |
| SARM1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MK06_HUMAN | [view interactions] | High throughput | no | yes |
| RIPK4_HUMAN | [view interactions] | High throughput | no | no |
| CAZA2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ORC1_HUMAN | [view interactions] | High throughput | no | yes |
| SAMD1_HUMAN | [view interactions] | High throughput | no | no |
| TTC5_HUMAN | [view interactions] | High throughput | no | yes |
| DCC1_HUMAN | [view interactions] | High throughput | no | yes |
| YTHD1_HUMAN | [view interactions] | High throughput | no | no |
| CYFP2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ECH1_HUMAN | [view interactions] | High throughput | no | yes |
| ST32C_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SG196_HUMAN | [view interactions] | High throughput | no | yes |
| NTRK1_HUMAN | [view interactions] | High throughput | no | yes |
| NTRK3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HSC20_HUMAN | [view interactions] | High throughput | no | yes |
| SDCB1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RTN3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LNX1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| M4A14_HUMAN | [view interactions] | High throughput | no | no |
| JAGN1_HUMAN | [view interactions] | High throughput | no | no |
| AQP6_HUMAN | [view interactions] | High throughput | no | no |
| RETR3_HUMAN | [view interactions] | High throughput | no | yes |
| GPX8_HUMAN | [view interactions] | High throughput | no | no |
| DHB13_HUMAN | [view interactions] | High throughput | no | yes |
| MGST3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NB5R3_HUMAN | [view interactions] | High throughput | no | yes |
| TMX2_HUMAN | [view interactions] | High throughput | no | yes |
| IR3IP_HUMAN | [view interactions] | High throughput | no | yes |
| FFAR2_HUMAN | [view interactions] | High throughput | no | yes |
| VMA21_HUMAN | [view interactions] | High throughput | no | no |
| GP101_HUMAN | [view interactions] | High throughput | no | no |
| SIG12_HUMAN | [view interactions] | High throughput | no | no |
| F209A_HUMAN | [view interactions] | High throughput | no | no |
| RN19B_HUMAN | [view interactions] | High throughput | no | yes |
| ERGI3_HUMAN | [view interactions] | High throughput | no | yes |
| AQP2_HUMAN | [view interactions] | High throughput | no | no |
| CTR1_HUMAN | [view interactions] | High throughput | no | no |
| CY561_HUMAN | [view interactions] | High throughput | no | yes |
| CISD2_HUMAN | [view interactions] | High throughput | no | yes |
| KCNK1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| IBP6_HUMAN | [view interactions] | High throughput | no | yes |
| CGRF1_HUMAN | [view interactions] | High throughput | no | yes |
| SCAI_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KI2L3_HUMAN | [view interactions] | High throughput | no | no |
| CXB1_HUMAN | [view interactions] | High throughput | no | yes |
| RELL2_HUMAN | [view interactions] | High throughput | no | no |
| TLCD4_HUMAN | [view interactions] | High throughput | no | no |
| MOT2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| IF3M_HUMAN | [view interactions] | High throughput | no | yes |
| GOLM1_HUMAN | [view interactions] | High throughput | no | yes |
| GP152_HUMAN | [view interactions] | High throughput | no | no |
| CD79A_HUMAN | [view interactions] | High throughput | no | no |
| EBP_HUMAN | [view interactions] | High throughput | no | no |
| SOAT_HUMAN | [view interactions] | High throughput | no | no |
| SYDM_HUMAN | [view interactions] | High throughput | no | yes |
| VA0E1_HUMAN | [view interactions] | High throughput | no | no |
| AR13B_HUMAN | [view interactions] | High throughput | no | yes |
| FKBP7_HUMAN | [view interactions] | High throughput | no | yes |
| ODFP4_HUMAN | [view interactions] | High throughput | no | no |
| CPLX4_HUMAN | [view interactions] | High throughput | no | no |
| GP151_HUMAN | [view interactions] | High throughput | no | no |
| BSND_HUMAN | [view interactions] | High throughput | no | no |
| TNR1A_HUMAN | [view interactions] | High throughput | no | yes |
| TNR1B_HUMAN | [view interactions] | High throughput | no | no |
| ILK_HUMAN | [view interactions] | High throughput | no | no |
| HIPK4_HUMAN | [view interactions] | High throughput | no | no |
| DYRK4_HUMAN | [view interactions] | High throughput | no | no |
| CTDP1_HUMAN | [view interactions] | High throughput | no | yes |
| UN93A_HUMAN | [view interactions] | High throughput | no | no |
| MYPR_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FCG2A_HUMAN | [view interactions] | High throughput | no | no |
| FCERG_HUMAN | [view interactions] | High throughput | no | no |
| MFF_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| EVI2B_HUMAN | [view interactions] | High throughput | no | no |
| KI2S2_HUMAN | [view interactions] | High throughput | no | no |
| NOS2_HUMAN | [view interactions] | High throughput | no | yes |
| UBL4A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MMS19_HUMAN | [view interactions] | High throughput | no | yes |
| CLN5_HUMAN | [view interactions] | High throughput | no | yes |
| EGFR_HUMAN | [view interactions] | High throughput | no | no |
| STAU1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PCSK9_HUMAN | [view interactions] | High throughput | no | no |