UBL4A_HUMAN
Evidence for PS localization
Functions
As part of a cytosolic protein quality control complex, the BAG6/BAT3 complex, maintains misfolded and hydrophobic patches-containing proteins in a soluble state and participates in their proper delivery to the endoplasmic reticulum or alternatively can promote their sorting to the proteasome where they undergo degradation (PubMed, PubMed, PubMed, PubMed). The BAG6/BAT3 complex is involved in the post-translational delivery of tail-anchored/type II transmembrane proteins to the endoplasmic reticulum membrane. Recruited to ribosomes, it interacts with the transmembrane region of newly synthesized tail-anchored proteins and together with SGTA and ASNA1 mediates their delivery to the endoplasmic reticulum (PubMed, PubMed, PubMed). Client proteins that cannot be properly delivered to the endoplasmic reticulum are ubiquitinated and sorted to the proteasome (PubMed). Similarly, the BAG6/BAT3 complex also functions as a sorting platform for proteins of the secretory pathway that are mislocalized to the cytosol either delivering them to the proteasome for degradation or to the endoplasmic reticulum (PubMed). The BAG6/BAT3 complex also plays a role in the endoplasmic reticulum-associated degradation (ERAD), a quality control mechanism that eliminates unwanted proteins of the endoplasmic reticulum through their retrotranslocation to the cytosol and their targeting to the proteasome. It maintains these retrotranslocated proteins in an unfolded yet soluble state condition in the cytosol to ensure their proper delivery to the proteasome (PubMed). [View more on UniProt]
Protein features
Binary interactions with known binding regions
To display all evidence describing the interaction with a partner, click on the protein name left to the bars.
Network
Isoforms
Disease-causing germline mutations
No data found.
Linear motifs
No annotated instance was found. To search for linear motifs, use the ELM prediction server.
Fingerprint
Molecular function
| Term | Name | % | Distance from the top of the tree | Annotated in UBL4A_HUMAN |
|---|---|---|---|---|
| GO:0003723 | RNA binding | 59.7765 | 4 | no |
| GO:0017076 | purine nucleotide binding | 24.0223 | 4 | no |
| GO:0032555 | purine ribonucleotide binding | 24.0223 | 4 | no |
| GO:0035639 | purine ribonucleoside triphosphate binding | 22.9050 | 4 | no |
Biological process
| Term | Name | % | Distance from top the of the tree | Annotated in UBL4A_HUMAN |
|---|---|---|---|---|
| GO:0044271 | cellular nitrogen compound biosynthetic process | 44.1341 | 4 | no |
| GO:0009059 | macromolecule biosynthetic process | 43.5754 | 4 | no |
| GO:0043603 | cellular amide metabolic process | 41.3408 | 4 | no |
| GO:0060255 | regulation of macromolecule metabolic process | 41.3408 | 4 | no |
| GO:1901566 | organonitrogen compound biosynthetic process | 40.7821 | 4 | no |
| GO:0006518 | peptide metabolic process | 40.2235 | 4 | no |
| GO:0034645 | cellular macromolecule biosynthetic process | 40.2235 | 4 | no |
| GO:0043604 | amide biosynthetic process | 40.2235 | 5 | no |
| GO:0080090 | regulation of primary metabolic process | 40.2235 | 4 | no |
| GO:0031323 | regulation of cellular metabolic process | 40.2235 | 4 | no |
| GO:0051171 | regulation of nitrogen compound metabolic process | 39.6648 | 4 | no |
| GO:0006412 | translation | 39.1061 | 4 | no |
| GO:0043043 | peptide biosynthetic process | 39.1061 | 5 | no |
| GO:0048522 | positive regulation of cellular process | 39.1061 | 4 | no |
| GO:0002181 | cytoplasmic translation | 36.8715 | 5 | no |
| GO:0048523 | negative regulation of cellular process | 31.8436 | 4 | no |
| GO:0010468 | regulation of gene expression | 31.2849 | 5 | no |
| GO:0009893 | positive regulation of metabolic process | 29.6089 | 4 | no |
| GO:0022607 | cellular component assembly | 29.0503 | 4 | no |
| GO:0006996 | organelle organization | 28.4916 | 4 | no |
| GO:0051246 | regulation of protein metabolic process | 27.9330 | 5 | no |
| GO:0071702 | organic substance transport | 26.8156 | 4 | yes |
| GO:0010604 | positive regulation of macromolecule metabolic process | 26.8156 | 5 | no |
| GO:0090304 | nucleic acid metabolic process | 25.6983 | 4 | no |
| GO:0008104 | protein localization | 25.1397 | 4 | yes |
| GO:0071705 | nitrogen compound transport | 25.1397 | 4 | yes |
| GO:0009889 | regulation of biosynthetic process | 25.1397 | 4 | no |
| GO:0031326 | regulation of cellular biosynthetic process | 24.5810 | 5 | no |
| GO:0010556 | regulation of macromolecule biosynthetic process | 24.0223 | 5 | no |
| GO:0010646 | regulation of cell communication | 23.4637 | 4 | no |
| GO:0051173 | positive regulation of nitrogen compound metabolic process | 23.4637 | 5 | no |
| GO:0019219 | regulation of nucleobase-containing compound metabolic process | 22.9050 | 5 | no |
| GO:0015031 | protein transport | 22.3464 | 4 | yes |
| GO:0009966 | regulation of signal transduction | 21.7877 | 4 | no |
| GO:0071310 | cellular response to organic substance | 21.7877 | 4 | no |
| GO:0031325 | positive regulation of cellular metabolic process | 21.7877 | 5 | no |
| GO:0051128 | regulation of cellular component organization | 21.2291 | 4 | no |
| GO:0016070 | RNA metabolic process | 20.1117 | 5 | no |
| GO:0009892 | negative regulation of metabolic process | 20.1117 | 4 | no |
| GO:0043933 | protein-containing complex organization | 20.1117 | 4 | no |
| GO:0006886 | intracellular protein transport | 17.8771 | 4 | yes |
| GO:0043412 | macromolecule modification | 15.0838 | 4 | yes |
| GO:0036211 | protein modification process | 14.5251 | 4 | yes |
| GO:0009057 | macromolecule catabolic process | 11.7318 | 4 | yes |
| GO:0033365 | protein localization to organelle | 11.7318 | 5 | yes |
| GO:0044265 | cellular macromolecule catabolic process | 10.0559 | 4 | yes |
| GO:0006508 | proteolysis | 8.9385 | 4 | yes |
| GO:0072594 | establishment of protein localization to organelle | 8.9385 | 4 | yes |
| GO:0019941 | modification-dependent protein catabolic process | 7.8212 | 6 | yes |
| GO:0043632 | modification-dependent macromolecule catabolic process | 7.8212 | 5 | yes |
| GO:0051603 | proteolysis involved in protein catabolic process | 7.8212 | 5 | yes |
| GO:0072657 | protein localization to membrane | 7.8212 | 4 | yes |
| GO:0006511 | ubiquitin-dependent protein catabolic process | 6.1453 | 7 | yes |
| GO:0090150 | establishment of protein localization to membrane | 6.1453 | 4 | yes |
| GO:0006605 | protein targeting | 5.0279 | 5 | yes |
| GO:0051205 | protein insertion into membrane | 2.7933 | 5 | yes |
| GO:0070972 | protein localization to endoplasmic reticulum | 2.7933 | 6 | yes |
| GO:0072599 | establishment of protein localization to endoplasmic reticulum | 2.7933 | 5 | yes |
| GO:0006612 | protein targeting to membrane | 2.2346 | 5 | yes |
| GO:0045047 | protein targeting to ER | 2.2346 | 6 | yes |
| GO:0006620 | post-translational protein targeting to endoplasmic reticulum membrane | 1.6760 | 6 | yes |
| GO:0045048 | protein insertion into ER membrane | 1.6760 | 6 | yes |
| GO:0071816 | tail-anchored membrane protein insertion into ER membrane | 1.6760 | 7 | yes |
Disease
| Term | Name | % | Distance from top the of the tree | Annotated in UBL4A_HUMAN |
|---|---|---|---|---|
| DOID:331 | central nervous system disease | 2.7933 | 3 | no |
| DOID:1289 | neurodegenerative disease | 2.2346 | 4 | no |
| DOID:231 | motor neuron disease | 1.6760 | 5 | no |
| DOID:0050539 | Charcot-Marie-Tooth disease type 2 | 1.1173 | 7 | no |
| DOID:10595 | Charcot-Marie-Tooth disease | 1.1173 | 6 | no |
| DOID:12377 | spinal muscular atrophy | 1.1173 | 6 | no |
| DOID:440 | neuromuscular disease | 1.1173 | 5 | no |
| DOID:574 | peripheral nervous system disease | 1.1173 | 3 | no |
| DOID:870 | neuropathy | 1.1173 | 4 | no |
| DOID:332 | amyotrophic lateral sclerosis | 1.1173 | 6 | no |
| DOID:936 | brain disease | 1.1173 | 4 | no |
All partners
| Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
|---|---|---|---|---|
| RN126_HUMAN | [view interactions] | Low throughput | no | yes |
| UBL4A_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| UBP13_HUMAN | [view interactions] | Low throughput | no | yes |
| SGTA_HUMAN | [view interactions] | Low throughput | no | yes |
| BAG6_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| FAF2_HUMAN | [view interactions] | Low throughput | no | yes |
| GET4_HUMAN | [view interactions] | Low throughput | no | yes |
| UBXN1_HUMAN | [view interactions] | Low throughput | no | no |
| PRKN_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| TRAF6_HUMAN | [view interactions] | Low throughput | no | yes |
| AMFR_HUMAN | [view interactions] | Low throughput | no | yes |
| SC61B_HUMAN | [view interactions] | Low throughput | no | yes |
| LAMP1_HUMAN | [view interactions] | High throughput | no | yes |
| CDV3_HUMAN | [view interactions] | High throughput | no | no |
| PGRC1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RBM27_HUMAN | [view interactions] | High throughput | no | yes |
| RAB10_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SUGP1_HUMAN | [view interactions] | High throughput | no | yes |
| RAB15_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SARNP_HUMAN | [view interactions] | High throughput | no | yes |
| RAB1A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PPIB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RAB1B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SODM_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RAB35_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| THY1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RAB8A_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| DUT_HUMAN | [view interactions] | High throughput | no | yes |
| RAB8B_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| SRC8_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PQBP1_HUMAN | [view interactions] | High throughput | no | yes |
| SRPRA_HUMAN | [view interactions] | High throughput | no | no |
| THIL_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SURF4_HUMAN | [view interactions] | High throughput | no | yes |
| RS28_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| UBQL1_HUMAN | [view interactions] | High throughput | no | yes |
| MK14_HUMAN | [view interactions] | High throughput | no | yes |
| HACL2_HUMAN | [view interactions] | High throughput | no | yes |
| MK11_HUMAN | [view interactions] | High throughput | no | yes |
| BAP31_HUMAN | [view interactions] | High throughput | no | yes |
| DNJ5G_HUMAN | [view interactions] | High throughput | no | no |
| CD320_HUMAN | [view interactions] | High throughput | no | yes |
| ACBD5_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PRAF3_HUMAN | [view interactions] | High throughput | no | yes |
| PXMP2_HUMAN | [view interactions] | High throughput | no | no |
| F162A_HUMAN | [view interactions] | High throughput | no | yes |
| RER1_HUMAN | [view interactions] | High throughput | no | yes |
| RAB14_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RB39A_HUMAN | [view interactions] | High throughput | no | no |
| SSBP_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| STX7_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| VAPB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DHC24_HUMAN | [view interactions] | High throughput | no | yes |
| AUP1_HUMAN | [view interactions] | High throughput | no | yes |
| CDIPT_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HSPB1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ILF2_HUMAN | [view interactions] | High throughput | no | yes |
| M2OM_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NDUA4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| P4HA1_HUMAN | [view interactions] | High throughput | no | yes |
| PDIA1_HUMAN | [view interactions] | High throughput | no | yes |
| RAB13_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| STX4_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| STXB3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TECR_HUMAN | [view interactions] | High throughput | no | yes |
| SSRD_HUMAN | [view interactions] | High throughput | no | yes |
| TMED1_HUMAN | [view interactions] | High throughput | no | yes |
| TMED9_HUMAN | [view interactions] | High throughput | no | yes |
| UB2G2_HUMAN | [view interactions] | High throughput | no | yes |
| IMA1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| IMB1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HS71B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HS71A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ANM5_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HSP7C_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MEP50_HUMAN | [view interactions] | High throughput | no | yes |
| HS71L_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| HSP76_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| OGT1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SPTN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ACTB_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ACTG_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HSP72_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| SPTB2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ATPB_HUMAN | [view interactions] | High throughput | no | yes |
| GEMI4_HUMAN | [view interactions] | High throughput | no | yes |
| ADT2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ATPA_HUMAN | [view interactions] | High throughput | no | yes |
| ACTC_HUMAN | [view interactions] | High throughput | no | no |
| ACTS_HUMAN | [view interactions] | High throughput | no | no |
| ACTA_HUMAN | [view interactions] | High throughput | no | no |
| ACTH_HUMAN | [view interactions] | High throughput | no | no |
| CH60_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GRP75_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GEMI5_HUMAN | [view interactions] | High throughput | no | yes |
| DDX20_HUMAN | [view interactions] | High throughput | no | no |
| EF2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DBLOH_HUMAN | [view interactions] | High throughput | no | no |
| DHB12_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RS27A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HNRPK_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CISY_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RPN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TBA1B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TBA1C_HUMAN | [view interactions] | High throughput | no | yes |
| RL40_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HNRPU_HUMAN | [view interactions] | High throughput | no | yes |
| RLA0_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TBB5_HUMAN | [view interactions] | High throughput | no | yes |
| ADT1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TBA1A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RL4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HNRH1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ADT3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| EFTU_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MPCP_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RSSA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RL9_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RS8_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| NUCL_HUMAN | [view interactions] | High throughput | no | yes |
| CLH1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HNRPC_HUMAN | [view interactions] | High throughput | no | yes |
| CALX_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RL7_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TBA3C_HUMAN | [view interactions] | High throughput | no | no |
| TBA3D_HUMAN | [view interactions] | High throughput | no | no |
| TBA3E_HUMAN | [view interactions] | High throughput | no | no |
| TBB4B_HUMAN | [view interactions] | High throughput | no | yes |
| RS18_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RL12_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TBB4A_HUMAN | [view interactions] | High throughput | no | yes |
| RS3A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| EF1A1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HNRPF_HUMAN | [view interactions] | High throughput | no | yes |
| PRP31_HUMAN | [view interactions] | High throughput | no | yes |
| SPIN1_HUMAN | [view interactions] | High throughput | no | no |
| SPNDC_HUMAN | [view interactions] | High throughput | no | yes |
| RIOK1_HUMAN | [view interactions] | High throughput | no | yes |
| RS3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RS4X_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RS2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RL13A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TBA8_HUMAN | [view interactions] | High throughput | no | yes |
| RL7A_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RS12_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RL10_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RS10_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RL28_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RL24_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HNRH2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HNRPM_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PHB2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CCAR1_HUMAN | [view interactions] | High throughput | no | yes |
| C1QBP_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HNRPQ_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ICLN_HUMAN | [view interactions] | High throughput | no | yes |
| RL6_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RACK1_HUMAN | [view interactions] | High throughput | no | yes |
| RL18_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RLA2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RS7_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RL13_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SMN_HUMAN | [view interactions] | High throughput | no | yes |
| HS90A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RS6_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ILF3_HUMAN | [view interactions] | High throughput | no | yes |
| COR1C_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ROA2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HNRPL_HUMAN | [view interactions] | High throughput | no | yes |
| PHB1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RS9_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RS5_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RL15_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RS16_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RS15A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RL14_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RL21_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RL31_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RL10A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HS90B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RU17_HUMAN | [view interactions] | High throughput | no | yes |
| PABP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SMD2_HUMAN | [view interactions] | High throughput | no | yes |
| PABP4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FUS_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HNRPR_HUMAN | [view interactions] | High throughput | no | yes |
| RPN2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TMEDA_HUMAN | [view interactions] | High throughput | no | yes |
| LMAN2_HUMAN | [view interactions] | High throughput | no | yes |
| TMED2_HUMAN | [view interactions] | High throughput | no | yes |
| RL5_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RL8_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SMD3_HUMAN | [view interactions] | High throughput | no | yes |
| RS19_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RL18A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RL23_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RL19_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RL30_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RL26_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RLA1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RL23A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RL36_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RS21_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RS24_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RL27A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RS14_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RS27_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RL38_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RL29_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| THIO_HUMAN | [view interactions] | High throughput | no | yes |
| 1433E_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PRDX1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NPM_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HUWE1_HUMAN | [view interactions] | High throughput | no | yes |
| ERH_HUMAN | [view interactions] | High throughput | no | yes |
| PCBP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PDE12_HUMAN | [view interactions] | High throughput | no | yes |
| PCBP2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| QCR1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GET3_HUMAN | [view interactions] | High throughput | no | yes |
| JAK1_HUMAN | [view interactions] | High throughput | no | yes |
| UFD1_HUMAN | [view interactions] | High throughput | no | no |
| RUXE_HUMAN | [view interactions] | High throughput | no | no |
| ERLN2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| WDR20_HUMAN | [view interactions] | High throughput | no | no |
| LRC59_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NPL4_HUMAN | [view interactions] | High throughput | no | yes |
| PRDX4_HUMAN | [view interactions] | High throughput | no | yes |
| RT22_HUMAN | [view interactions] | High throughput | no | yes |
| MK06_HUMAN | [view interactions] | High throughput | no | yes |
| ATPO_HUMAN | [view interactions] | High throughput | no | yes |
| RIPK4_HUMAN | [view interactions] | High throughput | no | no |
| FUBP2_HUMAN | [view interactions] | High throughput | no | yes |
| OTUB1_HUMAN | [view interactions] | High throughput | no | yes |
| ATPMK_HUMAN | [view interactions] | High throughput | no | no |
| UBE2K_HUMAN | [view interactions] | High throughput | no | yes |
| ROAA_HUMAN | [view interactions] | High throughput | no | yes |
| SMAD3_HUMAN | [view interactions] | High throughput | no | yes |
| RL3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PAEP_HUMAN | [view interactions] | High throughput | no | no |
| RS11_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| C170L_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RL11_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PRIC3_HUMAN | [view interactions] | High throughput | no | yes |
| RS26_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NCBP1_HUMAN | [view interactions] | High throughput | no | yes |
| RL32_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KPYM_HUMAN | [view interactions] | High throughput | no | yes |
| RL37A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MK03_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RS20_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| APOL2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RL36L_HUMAN | [view interactions] | High throughput | no | no |
| MYH9_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| PA2G4_HUMAN | [view interactions] | High throughput | no | yes |
| TF2B_HUMAN | [view interactions] | High throughput | no | yes |
| RS17_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KI21B_HUMAN | [view interactions] | High throughput | no | yes |
| RL22_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RB_HUMAN | [view interactions] | High throughput | no | yes |
| RL27_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CDK18_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TBB8_HUMAN | [view interactions] | High throughput | no | no |
| CDK8_HUMAN | [view interactions] | High throughput | no | no |
| RS25_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| IP6K3_HUMAN | [view interactions] | High throughput | no | no |
| RL34_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CERK1_HUMAN | [view interactions] | High throughput | no | no |
| LDHB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KIF2A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HIPK4_HUMAN | [view interactions] | High throughput | no | no |
| KI21A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FAF1_HUMAN | [view interactions] | High throughput | no | yes |
| VP26A_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| MOV10_HUMAN | [view interactions] | High throughput | no | no |
| BIP_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NXF1_HUMAN | [view interactions] | High throughput | no | yes |
| SGTB_HUMAN | [view interactions] | High throughput | no | yes |
| AMRA1_HUMAN | [view interactions] | High throughput | no | yes |
| HD_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| I5P2_HUMAN | [view interactions] | High throughput | no | yes |
| DUS2_HUMAN | [view interactions] | High throughput | no | no |
| RFXK_HUMAN | [view interactions] | High throughput | no | yes |
| KS6B1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DDI2_HUMAN | [view interactions] | High throughput | no | no |
| EGLN3_HUMAN | [view interactions] | High throughput | no | no |
| ULK4_HUMAN | [view interactions] | High throughput | no | yes |
| RMD5A_HUMAN | [view interactions] | High throughput | no | yes |
| RON_HUMAN | [view interactions] | High throughput | no | yes |
| TIE2_HUMAN | [view interactions] | High throughput | no | no |
| SHRPN_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SNW1_HUMAN | [view interactions] | High throughput | no | yes |
| RNF31_HUMAN | [view interactions] | High throughput | no | yes |
| CDC5L_HUMAN | [view interactions] | High throughput | no | yes |
| PSDE_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MEOX2_HUMAN | [view interactions] | High throughput | no | no |
| APC4_HUMAN | [view interactions] | High throughput | no | yes |
| CDA7L_HUMAN | [view interactions] | High throughput | no | yes |
| ATX3_HUMAN | [view interactions] | High throughput | no | yes |
| TRAF4_HUMAN | [view interactions] | High throughput | no | yes |
| TR10A_HUMAN | [view interactions] | High throughput | no | no |
| PER2_HUMAN | [view interactions] | High throughput | no | yes |
| LMBRL_HUMAN | [view interactions] | High throughput | no | no |
| TRI54_HUMAN | [view interactions] | High throughput | no | no |
| S100P_HUMAN | [view interactions] | High throughput | no | no |
| KCC2A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ERP27_HUMAN | [view interactions] | High throughput | no | no |
| PSB2_HUMAN | [view interactions] | High throughput | no | yes |
| FGFR3_HUMAN | [view interactions] | High throughput | no | yes |
| ABCG2_HUMAN | [view interactions] | High throughput | no | no |
| M3K3_HUMAN | [view interactions] | High throughput | no | no |
| FZR1_HUMAN | [view interactions] | High throughput | no | no |
| CDK9_HUMAN | [view interactions] | High throughput | no | yes |
| ZBTB2_HUMAN | [view interactions] | High throughput | no | yes |
| RN185_HUMAN | [view interactions] | High throughput | no | no |
| FUZZY_HUMAN | [view interactions] | High throughput | no | yes |
| UBC_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SRC_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| KPCA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TERA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| UBL4B_HUMAN | [view interactions] | High throughput | no | no |
| PRAME_HUMAN | [view interactions] | High throughput | no | no |
| MYEOV_HUMAN | [view interactions] | High throughput | no | no |
| EFMT3_HUMAN | [view interactions] | High throughput | no | no |
| ZRAN1_HUMAN | [view interactions] | High throughput | no | yes |
| MET23_HUMAN | [view interactions] | High throughput | no | no |
| FBX7_HUMAN | [view interactions] | High throughput | no | yes |
| HSP74_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RB11A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MOGS_HUMAN | [view interactions] | High throughput | no | yes |
| RAB7A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SRPRB_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| FAS_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CBPD_HUMAN | [view interactions] | High throughput | no | yes |
| FDFT_HUMAN | [view interactions] | High throughput | no | yes |
| A4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PLOD2_HUMAN | [view interactions] | High throughput | no | yes |
| RM53_HUMAN | [view interactions] | High throughput | no | yes |
| SC22B_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| SERPH_HUMAN | [view interactions] | High throughput | no | no |
| HACD3_HUMAN | [view interactions] | High throughput | no | yes |
| NDUA2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ATP5H_HUMAN | [view interactions] | High throughput | no | yes |
| NDUA7_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| XYLK_HUMAN | [view interactions] | High throughput | no | yes |
| SCP2_HUMAN | [view interactions] | High throughput | no | no |
| CAMLG_HUMAN | [view interactions] | Computational | no | yes |
| G6PD_HUMAN | [view entry] [view interactions] | Computational | yes | no |