Features Interactions Isoform Disease Linear motifs Fingerprint Network All partners

HSP72_HUMAN

GO
G2C
SynGO

Molecular chaperone implicated in a wide variety of cellular processes, including protection of the proteome from stress, folding and transport of newly synthesized polypeptides, activation of proteolysis of misfolded proteins and the formation and dissociation of protein complexes. Plays a pivotal role in the protein quality control system, ensuring the correct folding of proteins, the re-folding of misfolded proteins and controlling the targeting of proteins for subsequent degradation. This is achieved through cycles of ATP binding, ATP hydrolysis and ADP release, mediated by co-chaperones. The affinity for polypeptides is regulated by its nucleotide bound state. In the ATP-bound form, it has a low affinity for substrate proteins. However, upon hydrolysis of the ATP to ADP, it undergoes a conformational change that increases its affinity for substrate proteins. It goes through repeated cycles of ATP hydrolysis and nucleotide exchange, which permits cycles of substrate binding and release (PubMed). Plays a role in spermatogenesis. In association with SHCBP1L may participate in the maintenance of spindle integrity during meiosis in male germ cells . [View more on UniProt]

Interacting region for partners were not defined.

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No data found.

No data found.

ELM instance Name Type Start End Partner
ELMI000038 LIG_TPR LIG 636 639 -

Molecular function

Term Name % Distance from the top of the tree Annotated in HSP72_HUMAN
GO:0017076 purine nucleotide binding 36.6337 4 yes
GO:0032555 purine ribonucleotide binding 33.6634 4 yes
GO:0035639 purine ribonucleoside triphosphate binding 33.6634 4 yes
GO:0030554 adenyl nucleotide binding 31.6832 5 yes
GO:0005524 ATP binding 28.7129 5 yes
GO:0032559 adenyl ribonucleotide binding 28.7129 5 yes
GO:0019900 kinase binding 26.7327 4 no
GO:0019901 protein kinase binding 23.7624 5 no
GO:0016462 pyrophosphatase activity 18.8119 5 yes
GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 18.8119 4 yes
GO:0017111 ribonucleoside triphosphate phosphatase activity 18.8119 6 yes
GO:0016887 ATP hydrolysis activity 11.8812 7 yes
GO:0048156 tau protein binding 7.9208 4 yes
GO:0097718 disordered domain specific binding 6.9307 4 yes

Biological process

Term Name % Distance from top the of the tree Annotated in HSP72_HUMAN
GO:0048522 positive regulation of cellular process 57.4257 4 yes
GO:0060255 regulation of macromolecule metabolic process 55.4455 4 yes
GO:0080090 regulation of primary metabolic process 52.4752 4 yes
GO:0051171 regulation of nitrogen compound metabolic process 51.4851 4 yes
GO:0031323 regulation of cellular metabolic process 46.5347 4 yes
GO:0048523 negative regulation of cellular process 45.5446 4 yes
GO:0051128 regulation of cellular component organization 44.5545 4 yes
GO:0010646 regulation of cell communication 42.5743 4 no
GO:0051246 regulation of protein metabolic process 40.5941 5 yes
GO:0006996 organelle organization 40.5941 4 yes
GO:0009966 regulation of signal transduction 39.6040 4 no
GO:0009893 positive regulation of metabolic process 39.6040 4 yes
GO:0010604 positive regulation of macromolecule metabolic process 35.6436 5 yes
GO:0051049 regulation of transport 34.6535 4 yes
GO:0010468 regulation of gene expression 34.6535 5 no
GO:0051173 positive regulation of nitrogen compound metabolic process 33.6634 5 yes
GO:0008104 protein localization 33.6634 4 no
GO:0031399 regulation of protein modification process 32.6733 6 yes
GO:1902531 regulation of intracellular signal transduction 31.6832 5 no
GO:0022607 cellular component assembly 30.6931 4 no
GO:0009892 negative regulation of metabolic process 30.6931 4 no
GO:0010605 negative regulation of macromolecule metabolic process 30.6931 5 no
GO:0010941 regulation of cell death 30.6931 4 no
GO:0051247 positive regulation of protein metabolic process 29.7030 6 yes
GO:0009894 regulation of catabolic process 29.7030 4 no
GO:0031325 positive regulation of cellular metabolic process 29.7030 5 yes
GO:0071310 cellular response to organic substance 28.7129 4 yes
GO:0042981 regulation of apoptotic process 28.7129 6 no
GO:0043067 regulation of programmed cell death 28.7129 5 no
GO:0044087 regulation of cellular component biogenesis 27.7228 4 yes
GO:0051174 regulation of phosphorus metabolic process 27.7228 5 yes
GO:0060341 regulation of cellular localization 27.7228 4 no
GO:0009889 regulation of biosynthetic process 27.7228 4 no
GO:0010556 regulation of macromolecule biosynthetic process 27.7228 5 no
GO:0051172 negative regulation of nitrogen compound metabolic process 27.7228 5 no
GO:0019220 regulation of phosphate metabolic process 27.7228 6 yes
GO:0071702 organic substance transport 26.7327 4 no
GO:0033043 regulation of organelle organization 26.7327 5 no
GO:0010647 positive regulation of cell communication 25.7426 5 no
GO:0023056 positive regulation of signaling 25.7426 4 no
GO:0071705 nitrogen compound transport 25.7426 4 no
GO:0019219 regulation of nucleobase-containing compound metabolic process 25.7426 5 no
GO:0031326 regulation of cellular biosynthetic process 25.7426 5 no
GO:0036211 protein modification process 24.7525 4 no
GO:0043412 macromolecule modification 24.7525 4 no
GO:0048584 positive regulation of response to stimulus 24.7525 4 no
GO:0031324 negative regulation of cellular metabolic process 24.7525 5 no
GO:0042325 regulation of phosphorylation 23.7624 7 yes
GO:0051130 positive regulation of cellular component organization 23.7624 5 no
GO:0043933 protein-containing complex organization 22.7723 4 no
GO:0015031 protein transport 22.7723 4 no
GO:0032880 regulation of protein localization 22.7723 5 no
GO:0051338 regulation of transferase activity 22.7723 4 no
GO:0080134 regulation of response to stress 22.7723 4 no
GO:0016192 vesicle-mediated transport 22.7723 4 yes
GO:0051252 regulation of RNA metabolic process 21.7822 5 no
GO:0009967 positive regulation of signal transduction 21.7822 5 no
GO:0031329 regulation of cellular catabolic process 21.7822 5 no
GO:0060548 negative regulation of cell death 21.7822 5 no
GO:0051129 negative regulation of cellular component organization 20.7921 5 yes
GO:0006355 regulation of DNA-templated transcription 20.7921 6 no
GO:1903506 regulation of nucleic acid-templated transcription 20.7921 7 no
GO:2001141 regulation of RNA biosynthetic process 20.7921 6 no
GO:0043066 negative regulation of apoptotic process 20.7921 7 no
GO:0043069 negative regulation of programmed cell death 20.7921 6 no
GO:0001932 regulation of protein phosphorylation 20.7921 7 yes
GO:0051050 positive regulation of transport 19.8020 4 yes
GO:0031401 positive regulation of protein modification process 19.8020 7 yes
GO:0006986 response to unfolded protein 16.8317 4 yes
GO:0045937 positive regulation of phosphate metabolic process 14.8515 7 yes
GO:0051726 regulation of cell cycle 14.8515 4 yes
GO:0010562 positive regulation of phosphorus metabolic process 14.8515 6 yes
GO:0042327 positive regulation of phosphorylation 13.8614 8 yes
GO:0001934 positive regulation of protein phosphorylation 11.8812 8 yes
GO:0034762 regulation of transmembrane transport 10.8911 4 yes
GO:0043269 regulation of ion transport 10.8911 5 yes
GO:0010564 regulation of cell cycle process 10.8911 5 yes
GO:0034765 regulation of ion transmembrane transport 8.9109 5 yes
GO:0035967 cellular response to topologically incorrect protein 8.9109 4 yes
GO:0051084 de novo post-translational protein folding 8.9109 4 yes
GO:0051085 chaperone cofactor-dependent protein refolding 8.9109 4 yes
GO:0022411 cellular component disassembly 8.9109 4 yes
GO:0034620 cellular response to unfolded protein 7.9208 5 yes
GO:0090083 regulation of inclusion body assembly 7.9208 5 yes
GO:0090084 negative regulation of inclusion body assembly 6.9307 6 yes
GO:1901987 regulation of cell cycle phase transition 6.9307 6 yes
GO:1901990 regulation of mitotic cell cycle phase transition 6.9307 6 yes
GO:1904062 regulation of cation transmembrane transport 6.9307 6 yes
GO:0007346 regulation of mitotic cell cycle 6.9307 5 yes
GO:0032412 regulation of ion transmembrane transporter activity 5.9406 5 yes
GO:0045787 positive regulation of cell cycle 5.9406 5 yes
GO:0051276 chromosome organization 5.9406 5 yes
GO:0010959 regulation of metal ion transport 5.9406 6 yes
GO:0022898 regulation of transmembrane transporter activity 5.9406 4 yes
GO:0034764 positive regulation of transmembrane transport 4.9505 5 yes
GO:0043270 positive regulation of ion transport 4.9505 5 yes
GO:0051924 regulation of calcium ion transport 4.9505 7 yes
GO:0090068 positive regulation of cell cycle process 4.9505 6 yes
GO:1903169 regulation of calcium ion transmembrane transport 4.9505 7 yes
GO:0032414 positive regulation of ion transmembrane transporter activity 3.9604 5 yes
GO:0032781 positive regulation of ATP-dependent activity 3.9604 4 yes
GO:0034767 positive regulation of ion transmembrane transport 3.9604 6 yes
GO:0048285 organelle fission 3.9604 5 yes
GO:0051928 positive regulation of calcium ion transport 3.9604 6 yes
GO:1901019 regulation of calcium ion transmembrane transporter activity 3.9604 6 yes
GO:1901021 positive regulation of calcium ion transmembrane transporter activity 3.9604 6 yes
GO:1902749 regulation of cell cycle G2/M phase transition 3.9604 7 yes
GO:1904064 positive regulation of cation transmembrane transport 3.9604 7 yes
GO:1904427 positive regulation of calcium ion transmembrane transport 3.9604 7 yes
GO:0010389 regulation of G2/M transition of mitotic cell cycle 3.9604 7 yes
GO:0032411 positive regulation of transporter activity 3.9604 4 yes
GO:0045931 positive regulation of mitotic cell cycle 2.9703 6 yes
GO:0048232 male gamete generation 2.9703 4 yes
GO:0070193 synaptonemal complex organization 2.9703 6 yes
GO:1901989 positive regulation of cell cycle phase transition 2.9703 7 yes
GO:1901992 positive regulation of mitotic cell cycle phase transition 2.9703 7 yes
GO:1902751 positive regulation of cell cycle G2/M phase transition 2.9703 8 yes
GO:0010971 positive regulation of G2/M transition of mitotic cell cycle 2.9703 8 yes
GO:0070194 synaptonemal complex disassembly 1.9802 5 yes
GO:1901894 regulation of ATPase-coupled calcium transmembrane transporter activity 1.9802 4 yes
GO:1901896 positive regulation of ATPase-coupled calcium transmembrane transporter activity 1.9802 5 yes
GO:0000280 nuclear division 1.9802 6 yes
GO:0007127 meiosis I 1.9802 4 yes
GO:0007141 male meiosis I 1.9802 4 yes
GO:0007286 spermatid development 1.9802 4 yes

Disease

Term Name % Distance from top the of the tree Annotated in HSP72_HUMAN
DOID:574 peripheral nervous system disease 3.9604 3 no
DOID:870 neuropathy 3.9604 4 no
DOID:440 neuromuscular disease 2.9703 5 no
DOID:10595 Charcot-Marie-Tooth disease 1.9802 6 no
Uniprot ID Details Highest evidence Localizing into PSD HPA (protein expression in neurons)
HSP72_HUMAN [view entry] [view interactions] Low throughput yes no
CDK1_HUMAN [view interactions] Low throughput no no
NASP_HUMAN [view interactions] Low throughput no yes
PARP2_HUMAN [view interactions] Low throughput no yes
PARP1_HUMAN [view entry] [view interactions] Low throughput yes yes
CTSR1_HUMAN [view interactions] Low throughput no no
PP1G_HUMAN [view entry] [view interactions] Low throughput yes yes
H2A1_HUMAN [view interactions] Low throughput no yes
H2A2A_HUMAN [view interactions] Low throughput no yes
H2A1B_HUMAN [view interactions] Low throughput no yes
H2A1D_HUMAN [view interactions] Low throughput no yes
H2A1A_HUMAN [view interactions] Low throughput no yes
H2AJ_HUMAN [view interactions] Low throughput no yes
H2A3_HUMAN [view interactions] Low throughput no yes
H2A2B_HUMAN [view interactions] Low throughput no yes
H2A1J_HUMAN [view interactions] Low throughput no yes
H2AX_HUMAN [view interactions] Low throughput no yes
H2A1C_HUMAN [view interactions] Low throughput no yes
H2A1H_HUMAN [view interactions] Low throughput no yes
H2A2C_HUMAN [view interactions] Low throughput no yes
BAG6_HUMAN [view entry] [view interactions] Low throughput yes yes
CRBN_HUMAN [view interactions] Low throughput no yes
FUND1_HUMAN [view interactions] Low throughput no yes
SAE1_HUMAN [view entry] [view interactions] Low throughput yes yes
HIF1A_HUMAN [view interactions] Low throughput no no
R144A_HUMAN [view interactions] Low throughput no yes
SNW1_HUMAN [view interactions] High throughput no yes
KIF11_HUMAN [view interactions] High throughput no yes
GALT9_HUMAN [view interactions] High throughput no no
HMCES_HUMAN [view interactions] High throughput no yes
EMSY_HUMAN [view interactions] High throughput no yes
SF3A1_HUMAN [view interactions] High throughput no yes
RAVR1_HUMAN [view interactions] High throughput no yes
KLC2_HUMAN [view entry] [view interactions] High throughput yes yes
EDRF1_HUMAN [view interactions] High throughput no no
CBL_HUMAN [view interactions] High throughput no yes
SKA3_HUMAN [view interactions] High throughput no no
TLN1_HUMAN [view entry] [view interactions] High throughput yes no
HMGN5_HUMAN [view interactions] High throughput no no
GADL1_HUMAN [view interactions] High throughput no no
PTN23_HUMAN [view entry] [view interactions] High throughput yes yes
MD1L1_HUMAN [view interactions] High throughput no yes
DBNL_HUMAN [view entry] [view interactions] High throughput yes yes
SNX20_HUMAN [view interactions] High throughput no no
PDLI5_HUMAN [view entry] [view interactions] High throughput yes no
MP2K2_HUMAN [view entry] [view interactions] High throughput yes yes
DLG4_HUMAN [view entry] [view interactions] High throughput yes yes
SPAG1_HUMAN [view interactions] High throughput no no
NPHP4_HUMAN [view interactions] High throughput no yes
CHM4A_HUMAN [view interactions] High throughput no no
BAG4_HUMAN [view interactions] High throughput no yes
ARNT_HUMAN [view entry] [view interactions] High throughput yes yes
CHIP_HUMAN [view entry] [view interactions] High throughput yes yes
MINT_HUMAN [view interactions] High throughput no yes
PR15A_HUMAN [view interactions] High throughput no yes
WDHD1_HUMAN [view interactions] High throughput no no
SIK2_HUMAN [view interactions] High throughput no yes
BL1S3_HUMAN [view interactions] High throughput no no
AKAP5_HUMAN [view entry] [view interactions] High throughput yes yes
ESS2_HUMAN [view interactions] High throughput no yes
BAG2_HUMAN [view entry] [view interactions] High throughput yes no
FKB15_HUMAN [view entry] [view interactions] High throughput yes yes
DNJC7_HUMAN [view interactions] High throughput no yes
GRL1A_HUMAN [view interactions] High throughput no no
TT30B_HUMAN [view interactions] High throughput no no
MTMR6_HUMAN [view interactions] High throughput no no
THSD4_HUMAN [view interactions] High throughput no no
I2BP2_HUMAN [view interactions] High throughput no yes
HPBP1_HUMAN [view interactions] High throughput no yes
SRP54_HUMAN [view interactions] High throughput no yes
MIGA2_HUMAN [view interactions] High throughput no yes
VIGLN_HUMAN [view entry] [view interactions] High throughput yes yes
HSP7C_HUMAN [view entry] [view interactions] High throughput yes yes
AFAD_HUMAN [view interactions] High throughput no yes
KLH34_HUMAN [view interactions] High throughput no no
ERC6L_HUMAN [view interactions] High throughput no yes
THAP4_HUMAN [view interactions] High throughput no yes
C2D1A_HUMAN [view entry] [view interactions] High throughput yes yes
VSIG8_HUMAN [view interactions] High throughput no no
GEMI_HUMAN [view interactions] High throughput no no
ILK_HUMAN [view interactions] High throughput no no
TPD54_HUMAN [view interactions] High throughput no yes
ABH15_HUMAN [view interactions] High throughput no yes
RNH2B_HUMAN [view interactions] High throughput no yes
TSSK1_HUMAN [view interactions] High throughput no no
MYPT1_HUMAN [view entry] [view interactions] High throughput yes yes
SODC_HUMAN [view interactions] High throughput no yes
FNBP4_HUMAN [view interactions] High throughput no yes
XPO7_HUMAN [view entry] [view interactions] High throughput yes yes
RFX5_HUMAN [view interactions] High throughput no yes
NEK4_HUMAN [view interactions] High throughput no yes
P66B_HUMAN [view interactions] High throughput no yes
PRD16_HUMAN [view interactions] High throughput no no
CF298_HUMAN [view interactions] High throughput no yes
RIN3_HUMAN [view interactions] High throughput no yes
MBIP1_HUMAN [view interactions] High throughput no yes
MOT11_HUMAN [view interactions] High throughput no no
DP13B_HUMAN [view entry] [view interactions] High throughput yes yes
PPM1B_HUMAN [view interactions] High throughput no yes
SOLH1_HUMAN [view interactions] High throughput no no
JAZF1_HUMAN [view interactions] High throughput no yes
ARMC1_HUMAN [view interactions] High throughput no yes
NTM2F_HUMAN [view interactions] High throughput no no
GPKOW_HUMAN [view interactions] High throughput no yes
PEBB_HUMAN [view interactions] High throughput no no
DJC13_HUMAN [view entry] [view interactions] High throughput yes yes
CFTR_HUMAN [view interactions] High throughput no no
KCTD3_HUMAN [view interactions] High throughput no yes
MAX_HUMAN [view interactions] High throughput no yes
SLK_HUMAN [view entry] [view interactions] High throughput yes yes
TBB3_HUMAN [view entry] [view interactions] High throughput yes yes
SF3A3_HUMAN [view interactions] High throughput no yes
HPSE_HUMAN [view interactions] High throughput no no
ZN143_HUMAN [view interactions] High throughput no yes
ATPB_HUMAN [view interactions] High throughput no yes
CT2NL_HUMAN [view interactions] High throughput no yes
PSDE_HUMAN [view entry] [view interactions] High throughput yes yes
URGCP_HUMAN [view interactions] High throughput no yes
KCMA1_HUMAN [view entry] [view interactions] High throughput yes no
SF01_HUMAN [view interactions] High throughput no yes
MK03_HUMAN [view entry] [view interactions] High throughput yes yes
MYO5C_HUMAN [view entry] [view interactions] High throughput yes yes
JUN_HUMAN [view interactions] High throughput no yes
PIGQ_HUMAN [view interactions] High throughput no yes
MEIOC_HUMAN [view interactions] High throughput no no
CC038_HUMAN [view interactions] High throughput no yes
DNM1L_HUMAN [view entry] [view interactions] High throughput yes yes
KLH26_HUMAN [view interactions] High throughput no no
GSK3B_HUMAN [view entry] [view interactions] High throughput yes yes
NEDD1_HUMAN [view interactions] High throughput no yes
ARFG2_HUMAN [view entry] [view interactions] High throughput yes yes
EWS_HUMAN [view interactions] High throughput no yes
PO2F1_HUMAN [view interactions] High throughput no yes
MEOX2_HUMAN [view interactions] High throughput no no
PLIN3_HUMAN [view interactions] High throughput no yes
TRI38_HUMAN [view interactions] High throughput no yes
QSER1_HUMAN [view interactions] High throughput no yes
UBE2A_HUMAN [view interactions] High throughput no no
QRIC1_HUMAN [view interactions] High throughput no yes
LA_HUMAN [view interactions] High throughput no yes
MRTFA_HUMAN [view interactions] High throughput no yes
PER1_HUMAN [view interactions] High throughput no no
CC117_HUMAN [view interactions] High throughput no yes
NDF1_HUMAN [view interactions] High throughput no yes
ZN598_HUMAN [view interactions] High throughput no no
MIP_HUMAN [view interactions] High throughput no no
ASPP2_HUMAN [view interactions] High throughput no yes
M3K5_HUMAN [view interactions] High throughput no yes
PHAR4_HUMAN [view interactions] High throughput no yes
FOSL1_HUMAN [view interactions] High throughput no yes
PAPOA_HUMAN [view interactions] High throughput no yes
ZN124_HUMAN [view interactions] High throughput no no
DEN4C_HUMAN [view interactions] High throughput no yes
PSMF1_HUMAN [view interactions] High throughput no yes
ZN503_HUMAN [view interactions] High throughput no yes
SOCS6_HUMAN [view interactions] High throughput no yes
CKAP5_HUMAN [view entry] [view interactions] High throughput yes yes
ASH2L_HUMAN [view interactions] High throughput no yes
OSB11_HUMAN [view interactions] High throughput no no
PKHS1_HUMAN [view interactions] High throughput no no
PAXI1_HUMAN [view interactions] High throughput no no
KCD17_HUMAN [view interactions] High throughput no yes
ZN703_HUMAN [view interactions] High throughput no yes
FAKD1_HUMAN [view interactions] High throughput no yes
SHRM1_HUMAN [view interactions] High throughput no no
SRTD4_HUMAN [view interactions] High throughput no yes
LRC40_HUMAN [view entry] [view interactions] High throughput yes yes
WBP1L_HUMAN [view interactions] High throughput no yes
MARE2_HUMAN [view entry] [view interactions] High throughput yes yes
FGF21_HUMAN [view interactions] High throughput no no
KINH_HUMAN [view entry] [view interactions] High throughput yes no
DPOA2_HUMAN [view interactions] High throughput no yes
BCAM_HUMAN [view interactions] High throughput no yes
LAT2_HUMAN [view interactions] High throughput no no
TEX45_HUMAN [view interactions] High throughput no no
LAR4B_HUMAN [view interactions] High throughput no yes
PAK1_HUMAN [view entry] [view interactions] High throughput yes yes
BAHD1_HUMAN [view interactions] High throughput no no
HSF1_HUMAN [view interactions] High throughput no yes
RPC6_HUMAN [view interactions] High throughput no yes
SNX1_HUMAN [view entry] [view interactions] High throughput yes yes
TSN2_HUMAN [view interactions] High throughput no no
PTN13_HUMAN [view interactions] High throughput no yes
INCA1_HUMAN [view interactions] High throughput no no
ZN318_HUMAN [view interactions] High throughput no yes
SPT12_HUMAN [view interactions] High throughput no no
PAK2_HUMAN [view entry] [view interactions] High throughput yes no
SPAS1_HUMAN [view interactions] High throughput no no
CSTF3_HUMAN [view interactions] High throughput no yes
TMM61_HUMAN [view interactions] High throughput no no
PALLD_HUMAN [view interactions] High throughput no yes
ZN296_HUMAN [view interactions] High throughput no no
LRCH2_HUMAN [view interactions] High throughput no no
KAD8_HUMAN [view interactions] High throughput no no
CDC5L_HUMAN [view interactions] High throughput no yes
KLC3_HUMAN [view interactions] High throughput no no
CORO7_HUMAN [view interactions] High throughput no no
ASB9_HUMAN [view interactions] High throughput no no
PHC1_HUMAN [view interactions] High throughput no yes
CHMP7_HUMAN [view interactions] High throughput no yes
HGS_HUMAN [view entry] [view interactions] High throughput yes yes
PRR3_HUMAN [view interactions] High throughput no no
RPRD2_HUMAN [view interactions] High throughput no yes
ZKSC3_HUMAN [view interactions] High throughput no yes
NGAP_HUMAN [view entry] [view interactions] High throughput yes yes
HD_HUMAN [view entry] [view interactions] High throughput yes yes
TXLNG_HUMAN [view interactions] High throughput no no
M3K3_HUMAN [view interactions] High throughput no no
SF3A2_HUMAN [view interactions] High throughput no yes
RIPK2_HUMAN [view interactions] High throughput no yes
SCMC3_HUMAN [view interactions] High throughput no yes
TAB2_HUMAN [view interactions] High throughput no yes
ADAD2_HUMAN [view interactions] High throughput no no
EGFR_HUMAN [view interactions] High throughput no no
FWCH2_HUMAN [view interactions] High throughput no no
AKT2_HUMAN [view entry] [view interactions] High throughput yes yes
PKN3_HUMAN [view interactions] High throughput no yes
STK4_HUMAN [view interactions] High throughput no yes
MAVS_HUMAN [view interactions] High throughput no yes
NFKB1_HUMAN [view interactions] High throughput no yes
ABL2_HUMAN [view entry] [view interactions] High throughput yes yes
RNF34_HUMAN [view interactions] High throughput no no
CHD5_HUMAN [view interactions] High throughput no no
HSF2_HUMAN [view interactions] High throughput no no
SBNO1_HUMAN [view interactions] High throughput no yes
UN45B_HUMAN [view interactions] High throughput no no
TEDC1_HUMAN [view interactions] High throughput no no
PSMD2_HUMAN [view entry] [view interactions] High throughput yes yes
RNF37_HUMAN [view interactions] High throughput no no
HS105_HUMAN [view entry] [view interactions] High throughput yes yes
PRC2C_HUMAN [view interactions] High throughput no yes
FKBPL_HUMAN [view interactions] High throughput no yes
RIR2B_HUMAN [view interactions] High throughput no yes
PFD5_HUMAN [view interactions] High throughput no yes
RTF1_HUMAN [view interactions] High throughput no yes
TTC1_HUMAN [view interactions] High throughput no yes
UBAP2_HUMAN [view interactions] High throughput no yes
SCHI1_HUMAN [view interactions] High throughput no yes
WIZ_HUMAN [view interactions] High throughput no yes
TANK_HUMAN [view interactions] High throughput no yes
NOXO1_HUMAN [view interactions] High throughput no no
OTUD5_HUMAN [view interactions] High throughput no yes
OXSR1_HUMAN [view interactions] High throughput no yes
CDK9_HUMAN [view interactions] High throughput no yes
ADNP_HUMAN [view interactions] High throughput no yes
MEPCE_HUMAN [view interactions] High throughput no yes
PPWD1_HUMAN [view interactions] High throughput no yes
ROA1_HUMAN [view entry] [view interactions] High throughput yes yes
RAB15_HUMAN [view entry] [view interactions] High throughput yes yes
COP1_HUMAN [view interactions] High throughput no no
GBB2_HUMAN [view entry] [view interactions] High throughput yes yes
BAP1_HUMAN [view interactions] High throughput no yes
CB27A_HUMAN [view interactions] High throughput no no
CB27B_HUMAN [view interactions] High throughput no no
TASL_HUMAN [view interactions] High throughput no no
TRAF6_HUMAN [view interactions] High throughput no yes
GLPK5_HUMAN [view interactions] High throughput no yes
NCOA2_HUMAN [view interactions] High throughput no no
AL3B1_HUMAN [view interactions] High throughput no yes
NCOA1_HUMAN [view interactions] High throughput no yes
B4GT2_HUMAN [view interactions] High throughput no no
PSA3_HUMAN [view interactions] High throughput no no
LRC8E_HUMAN [view interactions] High throughput no no
SIR7_HUMAN [view interactions] High throughput no yes
O10H1_HUMAN [view interactions] High throughput no no
FBX25_HUMAN [view interactions] High throughput no no
CBPC6_HUMAN [view interactions] High throughput no yes
HS90A_HUMAN [view entry] [view interactions] High throughput yes yes
PLCB_HUMAN [view interactions] High throughput no yes
LEG12_HUMAN [view interactions] High throughput no no
SUMF2_HUMAN [view interactions] High throughput no yes
NOS2_HUMAN [view interactions] High throughput no yes
CLPB_HUMAN [view interactions] High throughput no yes
1433Z_HUMAN [view entry] [view interactions] High throughput yes yes
KCNC4_HUMAN [view entry] [view interactions] High throughput yes no
MLP3A_HUMAN [view entry] [view interactions] High throughput yes yes
TTLL5_HUMAN [view interactions] High throughput no yes
MT21A_HUMAN [view interactions] High throughput no yes
FA12_HUMAN [view interactions] High throughput no no
EFMT3_HUMAN [view interactions] High throughput no no
MTU1_HUMAN [view interactions] High throughput no no
UBL4A_HUMAN [view entry] [view interactions] High throughput yes yes
NDRG2_HUMAN [view entry] [view interactions] High throughput yes yes
HDAC6_HUMAN [view interactions] High throughput no yes
ZNT2_HUMAN [view interactions] High throughput no no
BAG3_HUMAN [view entry] [view interactions] High throughput yes no
UBP36_HUMAN [view interactions] High throughput no yes
PRKN_HUMAN [view entry] [view interactions] High throughput yes yes
MGT4B_HUMAN [view interactions] High throughput no no
LGR4_HUMAN [view interactions] High throughput no yes
FXL15_HUMAN [view interactions] High throughput no no
AURKA_HUMAN [view entry] [view interactions] High throughput yes no
TMPS5_HUMAN [view interactions] High throughput no no
CDN1A_HUMAN [view interactions] High throughput no no
NPRL3_HUMAN [view interactions] High throughput no yes
CP250_HUMAN [view interactions] High throughput no no
K2C8_HUMAN [view interactions] High throughput no no
CEP57_HUMAN [view interactions] High throughput no yes
LST8_HUMAN [view interactions] High throughput no yes
HAUS2_HUMAN [view interactions] High throughput no yes
DOK3_HUMAN [view interactions] High throughput no no
CEP76_HUMAN [view interactions] High throughput no yes
SNX21_HUMAN [view interactions] High throughput no yes
P53_HUMAN [view interactions] High throughput no no
CPLN2_HUMAN [view interactions] High throughput no yes
SIR6_HUMAN [view interactions] High throughput no yes
PLPL5_HUMAN [view interactions] High throughput no no
HEYL_HUMAN [view interactions] High throughput no no
LSME2_HUMAN [view interactions] High throughput no no
PELI3_HUMAN [view interactions] High throughput no yes
CDK20_HUMAN [view interactions] High throughput no yes
ZN488_HUMAN [view interactions] High throughput no no
BSND_HUMAN [view interactions] High throughput no no
DHDH_HUMAN [view interactions] High throughput no no
HEY1_HUMAN [view interactions] High throughput no yes
INF2_HUMAN [view entry] [view interactions] High throughput yes yes
CP2W1_HUMAN [view interactions] High throughput no no
GNB1L_HUMAN [view interactions] High throughput no yes
MYO1D_HUMAN [view entry] [view interactions] High throughput yes yes
DNSL2_HUMAN [view interactions] High throughput no no
PTEN_HUMAN [view entry] [view interactions] High throughput yes yes
RFPL2_HUMAN [view interactions] High throughput no no
GAN_HUMAN [view interactions] High throughput no yes
AP5Z1_HUMAN [view interactions] High throughput no yes
ALKB3_HUMAN [view interactions] High throughput no yes
CC020_HUMAN [view interactions] High throughput no no
MCM2_HUMAN [view interactions] High throughput no no
RAB6C_HUMAN [view interactions] High throughput no no
MCM5_HUMAN [view interactions] High throughput no no
AAKG3_HUMAN [view interactions] High throughput no no
KSR1_HUMAN [view interactions] High throughput no yes
ANM6_HUMAN [view interactions] High throughput no yes
FAF1_HUMAN [view interactions] High throughput no yes
RAPSN_HUMAN [view entry] [view interactions] High throughput yes no
CDC73_HUMAN [view interactions] High throughput no yes
WDR90_HUMAN [view interactions] High throughput no yes
WDTC1_HUMAN [view interactions] High throughput no yes
DIC_HUMAN [view interactions] High throughput no yes
DHR13_HUMAN [view interactions] High throughput no yes
RPTOR_HUMAN [view interactions] High throughput no yes
WDR86_HUMAN [view interactions] High throughput no no
PROD_HUMAN [view entry] [view interactions] High throughput yes yes
LIME1_HUMAN [view entry] [view interactions] High throughput yes yes
SNH28_HUMAN [view interactions] High throughput no no
FOXS1_HUMAN [view interactions] High throughput no yes
VWA2_HUMAN [view interactions] High throughput no no
SCAP_HUMAN [view interactions] High throughput no yes
FZR1_HUMAN [view interactions] High throughput no no
TLE2_HUMAN [view interactions] High throughput no yes
FXRD1_HUMAN [view interactions] High throughput no no
SEP12_HUMAN [view interactions] High throughput no no
FACD2_HUMAN [view interactions] High throughput no no
RFFL_HUMAN [view interactions] High throughput no yes
TRI25_HUMAN [view interactions] High throughput no yes
LOXL4_HUMAN [view interactions] High throughput no no
ESR1_HUMAN [view interactions] High throughput no no
TELT_HUMAN [view interactions] High throughput no no
UBQL2_HUMAN [view interactions] High throughput no yes
WDR37_HUMAN [view entry] [view interactions] High throughput yes yes
ZUP1_HUMAN [view interactions] High throughput no yes
BPIFC_HUMAN [view interactions] High throughput no no
RMD5A_HUMAN [view interactions] High throughput no yes
FA83F_HUMAN [view interactions] High throughput no no
FGFR1_HUMAN [view interactions] High throughput no yes
GATA1_HUMAN [view interactions] High throughput no no
TF65_HUMAN [view entry] [view interactions] High throughput yes yes
PRSR2_HUMAN [view interactions] High throughput no yes
UB2R1_HUMAN [view interactions] High throughput no yes
IQCF2_HUMAN [view interactions] High throughput no no
HEXI1_HUMAN [view interactions] High throughput no yes
NR1I3_HUMAN [view interactions] High throughput no no
LARP7_HUMAN [view interactions] High throughput no yes
TRABD_HUMAN [view interactions] High throughput no yes
RUNX1_HUMAN [view interactions] High throughput no yes
GDPD5_HUMAN [view interactions] High throughput no no
ERCC8_HUMAN [view interactions] High throughput no no
GBB1_HUMAN [view entry] [view interactions] High throughput yes yes
PPT1_HUMAN [view interactions] High throughput no yes
SPRTN_HUMAN [view interactions] High throughput no yes
AGR2_HUMAN [view interactions] High throughput no no
UBP11_HUMAN [view interactions] High throughput no yes
RECQ4_HUMAN [view interactions] High throughput no yes
NEB2_HUMAN [view entry] [view interactions] High throughput yes yes
BAG1_HUMAN [view interactions] High throughput no yes
VIR_HUMAN [view interactions] High throughput no yes
RHG18_HUMAN [view interactions] High throughput no yes
RC3H1_HUMAN [view interactions] High throughput no yes
HSP74_HUMAN [view entry] [view interactions] High throughput yes yes
CCND1_HUMAN [view interactions] High throughput no yes
TATD3_HUMAN [view interactions] High throughput no yes
GLUC_HUMAN [view interactions] High throughput no no
A4_HUMAN [view entry] [view interactions] High throughput yes yes
UBE3A_HUMAN [view interactions] High throughput no yes
NHLC2_HUMAN [view interactions] High throughput no yes
TAU_HUMAN [view entry] [view interactions] High throughput yes yes
DPPA3_HUMAN [view interactions] High throughput no no
EF1A1_HUMAN [view entry] [view interactions] High throughput yes yes
LMBRL_HUMAN [view interactions] High throughput no no
GRPE1_HUMAN [view interactions] High throughput no yes
SAP_HUMAN [view interactions] High throughput no yes
GRP75_HUMAN [view entry] [view interactions] High throughput yes yes
PKHA4_HUMAN [view interactions] High throughput no yes
STIP1_HUMAN [view entry] [view interactions] High throughput yes yes
PINK1_HUMAN [view interactions] High throughput no yes
ACOX1_HUMAN [view interactions] High throughput no yes
YAP1_HUMAN [view interactions] High throughput no yes
RAB7A_HUMAN [view entry] [view interactions] High throughput yes yes
TFCP2_HUMAN [view interactions] High throughput no no
MCAT_HUMAN [view interactions] High throughput no yes
CTRO_HUMAN [view entry] [view interactions] High throughput yes yes
DECR_HUMAN [view entry] [view interactions] High throughput yes yes
AIMP2_HUMAN [view interactions] High throughput no yes
MMP14_HUMAN [view interactions] High throughput no yes
BRD4_HUMAN [view interactions] High throughput no yes
NHRF1_HUMAN [view interactions] High throughput no no
NINL_HUMAN [view interactions] High throughput no yes
GCST_HUMAN [view interactions] High throughput no yes
CIC_HUMAN [view interactions] High throughput no yes
GSTM1_HUMAN [view interactions] High throughput no yes
GLI1_HUMAN [view interactions] High throughput no no
GSTM2_HUMAN [view entry] [view interactions] High throughput yes yes
HS90B_HUMAN [view entry] [view interactions] High throughput yes yes
RBM39_HUMAN [view interactions] High throughput no yes
SRC_HUMAN [view entry] [view interactions] High throughput yes no
DNJA1_HUMAN [view entry] [view interactions] High throughput yes yes
BICD1_HUMAN [view interactions] High throughput no yes
DNJA2_HUMAN [view entry] [view interactions] High throughput yes yes
ATX1_HUMAN [view interactions] High throughput no yes
DJB12_HUMAN [view interactions] High throughput no yes
CLCA_HUMAN [view entry] [view interactions] High throughput yes no
DJB14_HUMAN [view interactions] High throughput no yes
CLH1_HUMAN [view entry] [view interactions] High throughput yes yes
DNJB1_HUMAN [view entry] [view interactions] High throughput yes yes
HS74L_HUMAN [view entry] [view interactions] High throughput yes no
DNJB2_HUMAN [view entry] [view interactions] High throughput yes yes
F10A1_HUMAN [view interactions] High throughput no yes
DNJB4_HUMAN [view entry] [view interactions] High throughput yes yes
TBB5_HUMAN [view interactions] High throughput no yes
DNJB5_HUMAN [view interactions] High throughput no yes
DNJB6_HUMAN [view entry] [view interactions] High throughput yes yes
DNJB8_HUMAN [view interactions] High throughput no no
DJC12_HUMAN [view interactions] High throughput no yes
DJC16_HUMAN [view interactions] High throughput no no
DJC18_HUMAN [view interactions] High throughput no yes
DNJ5B_HUMAN [view interactions] High throughput no no
DNJC5_HUMAN [view interactions] High throughput no yes
HS71B_HUMAN [view entry] [view interactions] High throughput yes yes
HS71A_HUMAN [view entry] [view interactions] High throughput yes yes
NUCG_HUMAN [view entry] [view interactions] High throughput yes yes
DNJC9_HUMAN [view interactions] High throughput no yes
FKBP8_HUMAN [view entry] [view interactions] High throughput yes yes
BAG5_HUMAN [view entry] [view interactions] High throughput yes no
MLF2_HUMAN [view entry] [view interactions] High throughput yes yes
RPGF6_HUMAN [view interactions] High throughput no yes
SPN1_HUMAN [view interactions] High throughput no yes
BUB1B_HUMAN [view interactions] High throughput no no
PPM1M_HUMAN [view interactions] High throughput no yes
M3K7_HUMAN [view interactions] High throughput no yes
QKI_HUMAN [view interactions] High throughput no no
GAPD1_HUMAN [view entry] [view interactions] High throughput yes yes
ELP4_HUMAN [view interactions] High throughput no yes
FOXC1_HUMAN [view interactions] High throughput no no
RETST_HUMAN [view interactions] High throughput no yes
GABPA_HUMAN [view interactions] High throughput no no
SCYL2_HUMAN [view interactions] High throughput no yes
NUP62_HUMAN [view interactions] Computational no yes
UBC9_HUMAN [view interactions] Computational no yes
RAE1L_HUMAN [view interactions] Computational no no
DNJA3_HUMAN [view entry] [view interactions] Computational yes yes
DIDO1_HUMAN [view interactions] Computational no yes
NU107_HUMAN [view interactions] Computational no no
NUP85_HUMAN [view interactions] Computational no yes
NUP93_HUMAN [view interactions] Computational no yes
DNJA4_HUMAN [view interactions] Computational no yes
EP300_HUMAN [view interactions] Computational no yes
FKBP4_HUMAN [view entry] [view interactions] Computational yes yes
NUP35_HUMAN [view interactions] Computational no yes
NU133_HUMAN [view interactions] Computational no yes
P121A_HUMAN [view interactions] Computational no yes
NUP37_HUMAN [view interactions] Computational no yes
NU153_HUMAN [view interactions] Computational no yes
CBP_HUMAN [view interactions] Computational no yes
P121C_HUMAN [view interactions] Computational no yes
NU155_HUMAN [view interactions] Computational no yes
DJB13_HUMAN [view interactions] Computational no no
NU205_HUMAN [view interactions] Computational no no
CTSRB_HUMAN [view interactions] Computational no no
PRGR_HUMAN [view interactions] Computational no no
NUP88_HUMAN [view interactions] Computational no yes
SEC13_HUMAN [view entry] [view interactions] Computational yes yes
FKBP6_HUMAN [view interactions] Computational no no
NU214_HUMAN [view interactions] Computational no no
SEH1_HUMAN [view interactions] Computational no no
NUP42_HUMAN [view interactions] Computational no no
NUP50_HUMAN [view interactions] Computational no yes
DNJC2_HUMAN [view interactions] Computational no yes
NDC1_HUMAN [view interactions] Computational no yes
NU188_HUMAN [view interactions] Computational no yes
AAAS_HUMAN [view interactions] Computational no yes
TPR_HUMAN [view interactions] Computational no yes
CCAR2_HUMAN [view interactions] Computational no yes
NUP58_HUMAN [view interactions] Computational no yes
RBP2_HUMAN [view interactions] Computational no yes
TLR2_HUMAN [view interactions] Computational no no
NUP98_HUMAN [view interactions] Computational no no
NU160_HUMAN [view interactions] Computational no no
PO210_HUMAN [view interactions] Computational no yes
NUP43_HUMAN [view interactions] Computational no yes
AROS_HUMAN [view interactions] Computational no yes
NUP54_HUMAN [view interactions] Computational no yes