Features Interactions Isoform Disease Linear motifs Fingerprint Network All partners

TF65_HUMAN

Evidence for PS localization

GO
G2C
SynGO
SynaptomeDB
HPA (protein expression in neurons)

Functions

NF-kappa-B is a pleiotropic transcription factor present in almost all cell types and is the endpoint of a series of signal transduction events that are initiated by a vast array of stimuli related to many biological processes such as inflammation, immunity, differentiation, cell growth, tumorigenesis and apoptosis. NF-kappa-B is a homo- or heterodimeric complex formed by the Rel-like domain-containing proteins RELA/p65, RELB, NFKB1/p105, NFKB1/p50, REL and NFKB2/p52. The heterodimeric RELA-NFKB1 complex appears to be most abundant one. The dimers bind at kappa-B sites in the DNA of their target genes and the individual dimers have distinct preferences for different kappa-B sites that they can bind with distinguishable affinity and specificity. Different dimer combinations act as transcriptional activators or repressors, respectively. The NF-kappa-B heterodimeric RELA-NFKB1 and RELA-REL complexes, for instance, function as transcriptional activators. NF-kappa-B is controlled by various mechanisms of post-translational modification and subcellular compartmentalization as well as by interactions with other cofactors or corepressors. NF-kappa-B complexes are held in the cytoplasm in an inactive state complexed with members of the NF-kappa-B inhibitor (I-kappa-B) family. In a conventional activation pathway, I-kappa-B is phosphorylated by I-kappa-B kinases (IKKs) in response to different activators, subsequently degraded thus liberating the active NF-kappa-B complex which translocates to the nucleus. The inhibitory effect of I-kappa-B on NF-kappa-B through retention in the cytoplasm is exerted primarily through the interaction with RELA. RELA shows a weak DNA-binding site which could contribute directly to DNA binding in the NF-kappa-B complex. Beside its activity as a direct transcriptional activator, it is also able to modulate promoters accessibility to transcription factors and thereby indirectly regulate gene expression. Associates with chromatin at the NF-kappa-B promoter region via association with DDX1. Essential for cytokine gene expression in T-cells (PubMed). The NF-kappa-B homodimeric RELA-RELA complex appears to be involved in invasin-mediated activation of IL-8 expression. Key transcription factor regulating the IFN response during SARS-CoV-2 infection (PubMed). [View more on UniProt]

Protein features

Binary interactions with known binding regions

To display all evidence describing the interaction with a partner, click on the protein name left to the bars.

Network

Download full PS network for entry.

Isoforms

Disease-causing germline mutations

No data found.

Linear motifs

ELM instance Name Type Start End Partner
ELMI001961 DOC_WW_Pin1_4 DOC 251 256 -
ELMI001188 LIG_EH_1 LIG 138 142 -
ELMI002162 TRG_NLS_MonoExtC_3 TRG 301 307 -
ELMI001961 DOC_WW_Pin1_4 DOC 251 256 -
ELMI001188 LIG_EH_1 LIG 138 142 -
ELMI002162 TRG_NLS_MonoExtC_3 TRG 301 307 -

Fingerprint

Molecular function

Term Name % Distance from the top of the tree Annotated in TF65_HUMAN
GO:0043168 anion binding 36.1111 4 yes
GO:0000166 nucleotide binding 32.4074 4 no
GO:0017076 purine nucleotide binding 31.4815 5 no
GO:0030554 adenyl nucleotide binding 28.7037 6 no
GO:0032555 purine ribonucleotide binding 28.7037 4 no
GO:0035639 purine ribonucleoside triphosphate binding 28.7037 4 no
GO:0003723 RNA binding 28.7037 4 no
GO:0005524 ATP binding 25.9259 5 no
GO:0032559 adenyl ribonucleotide binding 25.9259 5 no
GO:0044389 ubiquitin-like protein ligase binding 23.1481 4 yes
GO:0043169 cation binding 23.1481 4 no
GO:0046872 metal ion binding 23.1481 5 no
GO:0031625 ubiquitin protein ligase binding 21.2963 5 yes
GO:0003677 DNA binding 20.3704 4 yes
GO:0019900 kinase binding 17.5926 4 yes
GO:0140297 DNA-binding transcription factor binding 16.6667 4 yes
GO:0019901 protein kinase binding 15.7407 5 yes
GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding 13.8889 5 yes
GO:0003690 double-stranded DNA binding 12.9630 5 yes
GO:0042803 protein homodimerization activity 12.0370 4 yes
GO:0000976 transcription cis-regulatory region binding 10.1852 5 yes
GO:0001067 transcription regulatory region nucleic acid binding 10.1852 4 yes
GO:0043565 sequence-specific DNA binding 10.1852 5 yes
GO:1990837 sequence-specific double-stranded DNA binding 10.1852 6 yes
GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding 8.3333 6 yes
GO:0000987 cis-regulatory region sequence-specific DNA binding 8.3333 6 yes
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding 7.4074 7 yes
GO:0042826 histone deacetylase binding 7.4074 4 yes
GO:0051059 NF-kappaB binding 6.4815 6 yes
GO:0031490 chromatin DNA binding 5.5556 4 yes
GO:0001046 core promoter sequence-specific DNA binding 4.6296 6 yes
GO:0001221 transcription coregulator binding 4.6296 4 yes
GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific 4.6296 4 yes
GO:0001223 transcription coactivator binding 3.7037 5 yes
GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding 2.7778 7 yes
GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific 2.7778 4 yes
GO:0140296 general transcription initiation factor binding 2.7778 4 yes
GO:0042301 phosphate ion binding 1.8519 5 yes
GO:0042805 actinin binding 1.8519 4 yes
GO:0071532 ankyrin repeat binding 1.8519 4 yes

Biological process

Term Name % Distance from top the of the tree Annotated in TF65_HUMAN
GO:0060255 regulation of macromolecule metabolic process 61.1111 4 yes
GO:0080090 regulation of primary metabolic process 60.1852 4 yes
GO:0048522 positive regulation of cellular process 58.3333 4 yes
GO:0031323 regulation of cellular metabolic process 55.5556 4 yes
GO:0048523 negative regulation of cellular process 51.8519 4 yes
GO:0009889 regulation of biosynthetic process 51.8519 4 yes
GO:0031326 regulation of cellular biosynthetic process 51.8519 5 yes
GO:0010556 regulation of macromolecule biosynthetic process 50.9259 5 yes
GO:0010468 regulation of gene expression 50.0000 6 yes
GO:0009893 positive regulation of metabolic process 48.1481 4 yes
GO:0010646 regulation of cell communication 45.3704 4 yes
GO:0019219 regulation of nucleobase-containing compound metabolic process 45.3704 5 yes
GO:0010604 positive regulation of macromolecule metabolic process 44.4444 5 yes
GO:0009966 regulation of signal transduction 43.5185 4 yes
GO:0051246 regulation of protein metabolic process 42.5926 5 yes
GO:0009892 negative regulation of metabolic process 42.5926 4 yes
GO:0010605 negative regulation of macromolecule metabolic process 41.6667 5 yes
GO:0051252 regulation of RNA metabolic process 40.7407 5 yes
GO:0051128 regulation of cellular component organization 39.8148 4 no
GO:0031325 positive regulation of cellular metabolic process 39.8148 5 yes
GO:2001141 regulation of RNA biosynthetic process 38.8889 6 yes
GO:0006355 regulation of DNA-templated transcription 38.8889 7 yes
GO:0031324 negative regulation of cellular metabolic process 37.9630 5 yes
GO:0043067 regulation of programmed cell death 35.1852 4 yes
GO:0008104 protein localization 35.1852 4 no
GO:0009891 positive regulation of biosynthetic process 35.1852 5 yes
GO:0031328 positive regulation of cellular biosynthetic process 35.1852 6 yes
GO:0042981 regulation of apoptotic process 34.2593 5 yes
GO:0006996 organelle organization 34.2593 4 no
GO:0048584 positive regulation of response to stimulus 33.3333 4 yes
GO:0048585 negative regulation of response to stimulus 33.3333 4 yes
GO:0010557 positive regulation of macromolecule biosynthetic process 33.3333 6 yes
GO:0051247 positive regulation of protein metabolic process 31.4815 6 yes
GO:1902531 regulation of intracellular signal transduction 31.4815 5 yes
GO:0036211 protein modification process 31.4815 4 no
GO:0043412 macromolecule modification 31.4815 4 no
GO:0009890 negative regulation of biosynthetic process 31.4815 5 yes
GO:0010558 negative regulation of macromolecule biosynthetic process 31.4815 6 yes
GO:0031327 negative regulation of cellular biosynthetic process 31.4815 6 yes
GO:0031399 regulation of protein modification process 30.5556 6 yes
GO:0006357 regulation of transcription by RNA polymerase II 29.6296 8 yes
GO:0010648 negative regulation of cell communication 29.6296 5 yes
GO:0023057 negative regulation of signaling 29.6296 4 yes
GO:0060341 regulation of cellular localization 28.7037 4 no
GO:0009894 regulation of catabolic process 28.7037 4 yes
GO:0009968 negative regulation of signal transduction 28.7037 5 yes
GO:0023056 positive regulation of signaling 28.7037 4 yes
GO:0045595 regulation of cell differentiation 27.7778 4 yes
GO:0010647 positive regulation of cell communication 27.7778 5 yes
GO:0045935 positive regulation of nucleobase-containing compound metabolic process 26.8519 5 yes
GO:0051248 negative regulation of protein metabolic process 26.8519 6 yes
GO:0071310 cellular response to organic substance 26.8519 4 yes
GO:0080134 regulation of response to stress 26.8519 4 yes
GO:0045934 negative regulation of nucleobase-containing compound metabolic process 25.9259 5 yes
GO:0071702 organic substance transport 25.9259 4 no
GO:0009967 positive regulation of signal transduction 25.9259 5 yes
GO:0051240 positive regulation of multicellular organismal process 25.0000 4 yes
GO:0090304 nucleic acid metabolic process 25.0000 4 yes
GO:0032880 regulation of protein localization 25.0000 5 no
GO:0071705 nitrogen compound transport 25.0000 4 no
GO:0022607 cellular component assembly 25.0000 4 no
GO:0042127 regulation of cell population proliferation 25.0000 4 yes
GO:0043066 negative regulation of apoptotic process 24.0741 6 yes
GO:0043069 negative regulation of programmed cell death 24.0741 5 yes
GO:0051726 regulation of cell cycle 24.0741 4 no
GO:0030162 regulation of proteolysis 24.0741 6 no
GO:0010628 positive regulation of gene expression 24.0741 7 yes
GO:0043933 protein-containing complex organization 23.1481 4 yes
GO:0051253 negative regulation of RNA metabolic process 23.1481 6 yes
GO:0051254 positive regulation of RNA metabolic process 23.1481 6 yes
GO:0006796 phosphate-containing compound metabolic process 23.1481 4 no
GO:0019220 regulation of phosphate metabolic process 23.1481 6 no
GO:0044087 regulation of cellular component biogenesis 23.1481 4 no
GO:0051049 regulation of transport 23.1481 4 no
GO:0051174 regulation of phosphorus metabolic process 23.1481 5 no
GO:0015031 protein transport 23.1481 4 no
GO:0051094 positive regulation of developmental process 22.2222 4 yes
GO:0045893 positive regulation of DNA-templated transcription 21.2963 8 yes
GO:0045944 positive regulation of transcription by RNA polymerase II 21.2963 9 yes
GO:1902680 positive regulation of RNA biosynthetic process 21.2963 7 yes
GO:0045892 negative regulation of DNA-templated transcription 20.3704 8 yes
GO:1902679 negative regulation of RNA biosynthetic process 20.3704 7 yes
GO:2000026 regulation of multicellular organismal development 20.3704 4 yes
GO:0010564 regulation of cell cycle process 20.3704 5 no
GO:0033043 regulation of organelle organization 20.3704 5 no
GO:0060284 regulation of cell development 19.4444 5 yes
GO:1901873 regulation of post-translational protein modification 19.4444 7 yes
GO:1903320 regulation of protein modification by small protein conjugation or removal 19.4444 8 yes
GO:0031400 negative regulation of protein modification process 19.4444 7 yes
GO:0045597 positive regulation of cell differentiation 18.5185 5 yes
GO:0050776 regulation of immune response 18.5185 4 yes
GO:1901701 cellular response to oxygen-containing compound 18.5185 4 yes
GO:0008284 positive regulation of cell population proliferation 18.5185 5 yes
GO:0032101 regulation of response to external stimulus 18.5185 4 yes
GO:0042176 regulation of protein catabolic process 18.5185 5 yes
GO:1902533 positive regulation of intracellular signal transduction 17.5926 6 yes
GO:0000122 negative regulation of transcription by RNA polymerase II 17.5926 9 yes
GO:0010243 response to organonitrogen compound 17.5926 4 yes
GO:0051093 negative regulation of developmental process 16.6667 4 yes
GO:1902532 negative regulation of intracellular signal transduction 16.6667 6 yes
GO:0009057 macromolecule catabolic process 16.6667 4 yes
GO:0009059 macromolecule biosynthetic process 16.6667 4 yes
GO:0014070 response to organic cyclic compound 16.6667 4 yes
GO:0016070 RNA metabolic process 16.6667 5 yes
GO:0032870 cellular response to hormone stimulus 16.6667 4 yes
GO:0051241 negative regulation of multicellular organismal process 15.7407 4 yes
GO:2001233 regulation of apoptotic signaling pathway 15.7407 5 yes
GO:0002684 positive regulation of immune system process 15.7407 4 yes
GO:0050778 positive regulation of immune response 14.8148 5 yes
GO:0009895 negative regulation of catabolic process 14.8148 5 yes
GO:0031347 regulation of defense response 14.8148 5 yes
GO:0033993 response to lipid 14.8148 4 yes
GO:0071417 cellular response to organonitrogen compound 13.8889 4 yes
GO:1901699 cellular response to nitrogen compound 13.8889 4 yes
GO:0141124 intracellular signaling cassette 12.9630 4 yes
GO:0001817 regulation of cytokine production 12.9630 4 yes
GO:0022603 regulation of anatomical structure morphogenesis 12.9630 4 yes
GO:0043434 response to peptide hormone 12.0370 4 yes
GO:0062197 cellular response to chemical stress 12.0370 4 yes
GO:1901565 organonitrogen compound catabolic process 12.0370 4 yes
GO:2001234 negative regulation of apoptotic signaling pathway 12.0370 6 yes
GO:0002831 regulation of response to biotic stimulus 12.0370 4 yes
GO:0045088 regulation of innate immune response 11.1111 5 yes
GO:0048545 response to steroid hormone 11.1111 4 yes
GO:0048732 gland development 11.1111 4 yes
GO:0001819 positive regulation of cytokine production 11.1111 5 yes
GO:0007167 enzyme-linked receptor protein signaling pathway 11.1111 4 yes
GO:0030155 regulation of cell adhesion 11.1111 4 yes
GO:0071824 protein-DNA complex organization 10.1852 5 yes
GO:0140546 defense response to symbiont 10.1852 4 yes
GO:0010720 positive regulation of cell development 10.1852 6 yes
GO:0030163 protein catabolic process 10.1852 4 yes
GO:0032103 positive regulation of response to external stimulus 10.1852 5 yes
GO:0034097 response to cytokine 10.1852 4 yes
GO:0034599 cellular response to oxidative stress 10.1852 4 yes
GO:0050767 regulation of neurogenesis 9.2593 6 yes
GO:0051091 positive regulation of DNA-binding transcription factor activity 9.2593 4 yes
GO:0051092 positive regulation of NF-kappaB transcription factor activity 9.2593 5 yes
GO:0051960 regulation of nervous system development 9.2593 5 yes
GO:0071363 cellular response to growth factor stimulus 9.2593 4 yes
GO:0071375 cellular response to peptide hormone stimulus 9.2593 5 yes
GO:0071396 cellular response to lipid 9.2593 5 yes
GO:1901874 negative regulation of post-translational protein modification 9.2593 8 yes
GO:1903321 negative regulation of protein modification by small protein conjugation or removal 9.2593 9 yes
GO:0006325 chromatin organization 9.2593 6 yes
GO:0007169 cell surface receptor protein tyrosine kinase signaling pathway 9.2593 5 yes
GO:0043122 regulation of canonical NF-kappaB signal transduction 8.3333 6 yes
GO:0045089 positive regulation of innate immune response 8.3333 6 yes
GO:0071345 cellular response to cytokine stimulus 8.3333 5 yes
GO:1901362 organic cyclic compound biosynthetic process 8.3333 4 yes
GO:0002833 positive regulation of response to biotic stimulus 8.3333 5 yes
GO:0006954 inflammatory response 8.3333 4 yes
GO:0019221 cytokine-mediated signaling pathway 8.3333 4 yes
GO:0031349 positive regulation of defense response 8.3333 5 yes
GO:0034654 nucleobase-containing compound biosynthetic process 8.3333 4 yes
GO:0045785 positive regulation of cell adhesion 7.4074 5 yes
GO:0141187 nucleic acid biosynthetic process 7.4074 5 yes
GO:2001236 regulation of extrinsic apoptotic signaling pathway 7.4074 6 yes
GO:0001889 liver development 7.4074 5 yes
GO:0022407 regulation of cell-cell adhesion 7.4074 5 yes
GO:0032774 RNA biosynthetic process 7.4074 5 yes
GO:0032868 response to insulin 7.4074 5 yes
GO:0043123 positive regulation of canonical NF-kappaB signal transduction 6.4815 7 yes
GO:1903037 regulation of leukocyte cell-cell adhesion 6.4815 6 yes
GO:1903039 positive regulation of leukocyte cell-cell adhesion 6.4815 7 yes
GO:0000302 response to reactive oxygen species 6.4815 4 yes
GO:2001237 negative regulation of extrinsic apoptotic signaling pathway 6.4815 7 yes
GO:0006351 DNA-templated transcription 6.4815 6 yes
GO:0022409 positive regulation of cell-cell adhesion 6.4815 6 yes
GO:0042177 negative regulation of protein catabolic process 6.4815 6 yes
GO:0042542 response to hydrogen peroxide 5.5556 4 yes
GO:0045765 regulation of angiogenesis 5.5556 5 yes
GO:0050769 positive regulation of neurogenesis 5.5556 6 yes
GO:0051962 positive regulation of nervous system development 5.5556 5 yes
GO:1901342 regulation of vasculature development 5.5556 5 yes
GO:1901654 response to ketone 5.5556 4 yes
GO:0002768 immune response-regulating cell surface receptor signaling pathway 5.5556 4 yes
GO:0009416 response to light stimulus 5.5556 4 yes
GO:0014013 regulation of gliogenesis 5.5556 7 yes
GO:0032677 regulation of interleukin-8 production 5.5556 5 yes
GO:0034614 cellular response to reactive oxygen species 5.5556 5 yes
GO:0045685 regulation of glial cell differentiation 4.6296 5 yes
GO:0050727 regulation of inflammatory response 4.6296 5 yes
GO:0070301 cellular response to hydrogen peroxide 4.6296 5 yes
GO:1901222 regulation of non-canonical NF-kappaB signal transduction 4.6296 6 yes
GO:1901224 positive regulation of non-canonical NF-kappaB signal transduction 4.6296 7 yes
GO:1902893 regulation of miRNA transcription 4.6296 7 yes
GO:1902895 positive regulation of miRNA transcription 4.6296 8 yes
GO:2000628 regulation of miRNA metabolic process 4.6296 6 yes
GO:2000630 positive regulation of miRNA metabolic process 4.6296 7 yes
GO:0002429 immune response-activating cell surface receptor signaling pathway 4.6296 4 yes
GO:0009411 response to UV 4.6296 5 yes
GO:0032757 positive regulation of interleukin-8 production 4.6296 6 yes
GO:0033233 regulation of protein sumoylation 4.6296 9 yes
GO:0035994 response to muscle stretch 4.6296 4 yes
GO:0043200 response to amino acid 3.7037 4 yes
GO:0045687 positive regulation of glial cell differentiation 3.7037 6 yes
GO:0046626 regulation of insulin receptor signaling pathway 3.7037 5 yes
GO:0051607 defense response to virus 3.7037 4 yes
GO:0071356 cellular response to tumor necrosis factor 3.7037 6 yes
GO:1901343 negative regulation of vasculature development 3.7037 5 yes
GO:2000181 negative regulation of blood vessel morphogenesis 3.7037 5 yes
GO:0002758 innate immune response-activating signaling pathway 3.7037 4 yes
GO:0007249 canonical NF-kappaB signal transduction 3.7037 5 yes
GO:0010574 regulation of vascular endothelial growth factor production 3.7037 5 yes
GO:0010575 positive regulation of vascular endothelial growth factor production 3.7037 6 yes
GO:0014015 positive regulation of gliogenesis 3.7037 7 yes
GO:0016525 negative regulation of angiogenesis 3.7037 6 yes
GO:0032652 regulation of interleukin-1 production 3.7037 5 yes
GO:0033209 tumor necrosis factor-mediated signaling pathway 3.7037 5 yes
GO:0033234 negative regulation of protein sumoylation 3.7037 10 yes
GO:0033273 response to vitamin 3.7037 4 yes
GO:0034612 response to tumor necrosis factor 3.7037 5 yes
GO:0046627 negative regulation of insulin receptor signaling pathway 2.7778 6 yes
GO:0046683 response to organophosphorus 2.7778 4 yes
GO:0050854 regulation of antigen receptor-mediated signaling pathway 2.7778 5 yes
GO:0050856 regulation of T cell receptor signaling pathway 2.7778 6 yes
GO:0050857 positive regulation of antigen receptor-mediated signaling pathway 2.7778 6 yes
GO:0050862 positive regulation of T cell receptor signaling pathway 2.7778 7 yes
GO:0051591 response to cAMP 2.7778 4 yes
GO:0070498 interleukin-1-mediated signaling pathway 2.7778 5 yes
GO:0070555 response to interleukin-1 2.7778 5 yes
GO:0099527 postsynapse to nucleus signaling pathway 2.7778 4 yes
GO:1900076 regulation of cellular response to insulin stimulus 2.7778 4 yes
GO:1900077 negative regulation of cellular response to insulin stimulus 2.7778 5 yes
GO:1901223 negative regulation of non-canonical NF-kappaB signal transduction 2.7778 7 yes
GO:1902003 regulation of amyloid-beta formation 2.7778 5 yes
GO:1902991 regulation of amyloid precursor protein catabolic process 2.7778 6 yes
GO:1904385 cellular response to angiotensin 2.7778 6 yes
GO:1990776 response to angiotensin 2.7778 5 yes
GO:0002220 innate immune response activating cell surface receptor signaling pathway 2.7778 5 yes
GO:0002221 pattern recognition receptor signaling pathway 2.7778 5 yes
GO:0002237 response to molecule of bacterial origin 2.7778 4 yes
GO:0002753 cytoplasmic pattern recognition receptor signaling pathway 2.7778 4 yes
GO:0014074 response to purine-containing compound 2.7778 5 yes
GO:0032495 response to muramyl dipeptide 2.7778 4 yes
GO:0032496 response to lipopolysaccharide 2.7778 4 yes
GO:0032570 response to progesterone 2.7778 5 yes
GO:0032651 regulation of interleukin-1 beta production 2.7778 6 yes
GO:0032675 regulation of interleukin-6 production 2.7778 5 yes
GO:0032731 positive regulation of interleukin-1 beta production 2.7778 7 yes
GO:0032732 positive regulation of interleukin-1 production 2.7778 6 yes
GO:0032755 positive regulation of interleukin-6 production 2.7778 6 yes
GO:0034248 regulation of amide metabolic process 2.7778 4 yes
GO:0038084 vascular endothelial growth factor signaling pathway 2.7778 6 yes
GO:0070391 response to lipoteichoic acid 1.8519 4 yes
GO:0070431 nucleotide-binding oligomerization domain containing 2 signaling pathway 1.8519 6 yes
GO:0070741 response to interleukin-6 1.8519 5 yes
GO:0071219 cellular response to molecule of bacterial origin 1.8519 4 yes
GO:0071222 cellular response to lipopolysaccharide 1.8519 5 yes
GO:0071223 cellular response to lipoteichoic acid 1.8519 5 yes
GO:0071224 cellular response to peptidoglycan 1.8519 5 yes
GO:0071316 cellular response to nicotine 1.8519 4 yes
GO:0071347 cellular response to interleukin-1 1.8519 6 yes
GO:0071354 cellular response to interleukin-6 1.8519 6 yes
GO:0140895 cell surface toll-like receptor signaling pathway 1.8519 7 yes
GO:1902004 positive regulation of amyloid-beta formation 1.8519 6 yes
GO:1902894 negative regulation of miRNA transcription 1.8519 8 yes
GO:1902993 positive regulation of amyloid precursor protein catabolic process 1.8519 7 yes
GO:1904994 regulation of leukocyte adhesion to vascular endothelial cell 1.8519 7 yes
GO:1904996 positive regulation of leukocyte adhesion to vascular endothelial cell 1.8519 8 yes
GO:2000629 negative regulation of miRNA metabolic process 1.8519 7 yes
GO:0002357 defense response to tumor cell 1.8519 4 yes
GO:0002752 cell surface pattern recognition receptor signaling pathway 1.8519 6 yes
GO:0006117 acetaldehyde metabolic process 1.8519 4 yes
GO:0006968 cellular defense response 1.8519 4 yes
GO:0007218 neuropeptide signaling pathway 1.8519 4 yes
GO:0010224 response to UV-B 1.8519 6 yes
GO:0014038 regulation of Schwann cell differentiation 1.8519 6 yes
GO:0014040 positive regulation of Schwann cell differentiation 1.8519 7 yes
GO:0032494 response to peptidoglycan 1.8519 4 yes
GO:0032655 regulation of interleukin-12 production 1.8519 5 yes
GO:0032735 positive regulation of interleukin-12 production 1.8519 6 yes
GO:0033590 response to cobalamin 1.8519 4 yes
GO:0034142 toll-like receptor 4 signaling pathway 1.8519 8 yes
GO:0034250 positive regulation of amide metabolic process 1.8519 5 yes
GO:0035728 response to hepatocyte growth factor 1.8519 4 yes
GO:0035729 cellular response to hepatocyte growth factor stimulus 1.8519 5 yes
GO:0035872 nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway 1.8519 5 yes
GO:0038061 non-canonical NF-kappaB signal transduction 1.8519 5 yes
GO:0038161 prolactin signaling pathway 1.8519 4 yes

Disease

No data found.

All partners

Uniprot ID Details Highest evidence Localizing into PSD HPA (protein expression in neurons)
TLE1_HUMAN [view interactions] Low throughput no yes
PARP1_HUMAN [view entry] [view interactions] Low throughput yes yes
MTPN_HUMAN [view interactions] Low throughput no yes
PO2F1_HUMAN [view interactions] Low throughput no yes
MYC_HUMAN [view interactions] Low throughput no yes
NKX21_HUMAN [view interactions] Low throughput no no
FUS_HUMAN [view entry] [view interactions] Low throughput yes yes
TBP_HUMAN [view interactions] Low throughput no yes
SIR5_HUMAN [view interactions] Low throughput no yes
UBP31_HUMAN [view interactions] Low throughput no yes
BRMS1_HUMAN [view interactions] Low throughput no yes
AKIP1_HUMAN [view interactions] Low throughput no no
ATF3_HUMAN [view interactions] Low throughput no yes
HDAC6_HUMAN [view interactions] Low throughput no yes
ANM1_HUMAN [view interactions] Low throughput no yes
MAFK_HUMAN [view interactions] Low throughput no no
PPARD_HUMAN [view interactions] Low throughput no yes
PSD10_HUMAN [view entry] [view interactions] Low throughput yes yes
MTA1_HUMAN [view interactions] Low throughput no yes
P63_HUMAN [view interactions] Low throughput no no
1433S_HUMAN [view entry] [view interactions] Low throughput yes yes
ZBT7B_HUMAN [view interactions] Low throughput no no
SP3_HUMAN [view interactions] Low throughput no no
CEBPZ_HUMAN [view interactions] Low throughput no no
HSP74_HUMAN [view entry] [view interactions] Low throughput yes yes
CHIP_HUMAN [view entry] [view interactions] Low throughput yes yes
EZH2_HUMAN [view interactions] Low throughput no no
SUZ12_HUMAN [view interactions] Low throughput no no
KLF4_HUMAN [view interactions] Low throughput no no
PIN1_HUMAN [view entry] [view interactions] Low throughput yes yes
ACTS_HUMAN [view interactions] Low throughput no no
FAF1_HUMAN [view interactions] Low throughput no yes
TBL1X_HUMAN [view interactions] Low throughput no yes
CHFR_HUMAN [view interactions] Low throughput no no
DNJA3_HUMAN [view entry] [view interactions] Low throughput yes yes
SOCS3_HUMAN [view interactions] Low throughput no yes
NANP8_HUMAN [view interactions] Low throughput no no
NANOG_HUMAN [view interactions] Low throughput no no
FEM1A_HUMAN [view interactions] Low throughput no no
UBP7_HUMAN [view interactions] Low throughput no yes
HIF1A_HUMAN [view interactions] Low throughput no no
ANM5_HUMAN [view entry] [view interactions] Low throughput yes yes
HS71B_HUMAN [view entry] [view interactions] Low throughput yes yes
HS71A_HUMAN [view entry] [view interactions] Low throughput yes yes
HSP7C_HUMAN [view entry] [view interactions] Low throughput yes yes
ASPP2_HUMAN [view interactions] Low throughput no yes
MBB1A_HUMAN [view interactions] Low throughput no yes
DHX9_HUMAN [view interactions] Low throughput no yes
KC1G1_HUMAN [view interactions] Low throughput no no
NCF1_HUMAN [view interactions] Low throughput no no
IKBB_HUMAN [view interactions] Low throughput no no
THIOM_HUMAN [view interactions] Low throughput no yes
IKBA_HUMAN [view interactions] Low throughput no yes
NFKB1_HUMAN [view interactions] Low throughput no yes
UXT_HUMAN [view interactions] Low throughput no yes
REL_HUMAN [view interactions] Low throughput no yes
TF65_HUMAN [view entry] [view interactions] Low throughput yes yes
IKBE_HUMAN [view entry] [view interactions] Low throughput yes yes
NPM_HUMAN [view entry] [view interactions] Low throughput yes yes
KEAP1_HUMAN [view interactions] Low throughput no yes
MED17_HUMAN [view interactions] Low throughput no no
SIX2_HUMAN [view interactions] Low throughput no no
KS6A5_HUMAN [view entry] [view interactions] Low throughput yes yes
TXNIP_HUMAN [view interactions] Low throughput no no
CSK21_HUMAN [view entry] [view interactions] Low throughput yes yes
CCNB1_HUMAN [view interactions] Low throughput no no
AATF_HUMAN [view interactions] Low throughput no yes
P53_HUMAN [view interactions] Low throughput no no
RS3_HUMAN [view entry] [view interactions] Low throughput yes yes
ECSIT_HUMAN [view interactions] Low throughput no yes
SIR6_HUMAN [view interactions] Low throughput no yes
SETD7_HUMAN [view interactions] Low throughput no yes
PDLI2_HUMAN [view interactions] Low throughput no no
UBC_HUMAN [view entry] [view interactions] Low throughput yes yes
CASK_HUMAN [view interactions] Low throughput no no
CUL2_HUMAN [view interactions] Low throughput no yes
CSN1_HUMAN [view interactions] Low throughput no no
SOCS1_HUMAN [view interactions] Low throughput no yes
COMD1_HUMAN [view interactions] Low throughput no yes
EHMT1_HUMAN [view interactions] Low throughput no yes
KAISO_HUMAN [view interactions] Low throughput no yes
GFI1_HUMAN [view interactions] Low throughput no yes
SIR1_HUMAN [view interactions] Low throughput no yes
PAK1_HUMAN [view entry] [view interactions] Low throughput yes yes
IKKA_HUMAN [view interactions] Low throughput no yes
DNM3L_HUMAN [view interactions] Low throughput no yes
BRD4_HUMAN [view interactions] Low throughput no yes
DAXX_HUMAN [view interactions] Low throughput no yes
CDX2_HUMAN [view interactions] Low throughput no no
IEX1_HUMAN [view interactions] Low throughput no yes
LOX5_HUMAN [view interactions] Low throughput no no
PDCD4_HUMAN [view interactions] Low throughput no yes
SNAI1_HUMAN [view interactions] Low throughput no yes
BECN1_HUMAN [view interactions] Low throughput no yes
CBP_HUMAN [view interactions] Low throughput no yes
KLF6_HUMAN [view interactions] Low throughput no yes
IRF5_HUMAN [view interactions] Low throughput no no
MKRN2_HUMAN [view interactions] Low throughput no yes
M3K8_HUMAN [view interactions] Low throughput no yes
VDR_HUMAN [view interactions] Low throughput no no
PIAS4_HUMAN [view interactions] Low throughput no yes
FBXW7_HUMAN [view interactions] Low throughput no yes
MYCD_HUMAN [view interactions] Low throughput no yes
TEAD4_HUMAN [view interactions] Low throughput no no
NOS2_HUMAN [view interactions] Low throughput no yes
NR4A1_HUMAN [view interactions] Low throughput no yes
DPF3_HUMAN [view interactions] Low throughput no yes
REQU_HUMAN [view interactions] Low throughput no yes
SQSTM_HUMAN [view interactions] Low throughput no yes
IMA3_HUMAN [view interactions] Low throughput no yes
FOS_HUMAN [view interactions] Low throughput no yes
HDAC3_HUMAN [view interactions] Low throughput no yes
PP2AA_HUMAN [view entry] [view interactions] Low throughput yes yes
RRP5_HUMAN [view interactions] Low throughput no yes
KAPCA_HUMAN [view entry] [view interactions] Low throughput yes yes
TF2B_HUMAN [view interactions] Low throughput no yes
HDAC1_HUMAN [view interactions] Low throughput no no
COMDA_HUMAN [view interactions] Low throughput no yes
COMD6_HUMAN [view interactions] Low throughput no no
CK5P3_HUMAN [view entry] [view interactions] Low throughput yes yes
UBB_HUMAN [view entry] [view interactions] Low throughput yes yes
RS27A_HUMAN [view entry] [view interactions] Low throughput yes yes
ZHX2_HUMAN [view interactions] Low throughput no yes
RL40_HUMAN [view entry] [view interactions] Low throughput yes yes
NMI_HUMAN [view interactions] Low throughput no yes
SETD6_HUMAN [view interactions] Low throughput no yes
ZFP91_HUMAN [view interactions] Low throughput no yes
2AAA_HUMAN [view entry] [view interactions] Low throughput yes no
RAD51_HUMAN [view interactions] Low throughput no yes
ESR1_HUMAN [view interactions] Low throughput no no
SAP18_HUMAN [view interactions] Low throughput no yes
TWST1_HUMAN [view interactions] Low throughput no no
UBP48_HUMAN [view interactions] Low throughput no yes
MEN1_HUMAN [view interactions] Low throughput no yes
MED16_HUMAN [view interactions] Low throughput no yes
MACD1_HUMAN [view entry] [view interactions] Low throughput yes no
TRIP6_HUMAN [view interactions] Low throughput no yes
NCOA3_HUMAN [view interactions] Low throughput no yes
EP300_HUMAN [view interactions] Low throughput no yes
F16P1_HUMAN [view interactions] Low throughput no no
NFKB2_HUMAN [view interactions] Low throughput no yes
TRIM7_HUMAN [view interactions] Low throughput no yes
TGM2_HUMAN [view interactions] Low throughput no no
SPSB1_HUMAN [view interactions] Low throughput no no
OGT1_HUMAN [view entry] [view interactions] Low throughput yes yes
LYRIC_HUMAN [view entry] [view interactions] Low throughput yes yes
TMUB1_HUMAN [view entry] [view interactions] Low throughput yes yes
NR4A2_HUMAN [view interactions] Low throughput no yes
RO52_HUMAN [view interactions] Low throughput no yes
STAT3_HUMAN [view entry] [view interactions] Low throughput yes yes
KMT2D_HUMAN [view interactions] Low throughput no yes
SP1_HUMAN [view interactions] Low throughput no yes
ANXA1_HUMAN [view entry] [view interactions] Low throughput yes no
NR0B2_HUMAN [view interactions] Low throughput no no
NR1H4_HUMAN [view interactions] Low throughput no no
GSK3B_HUMAN [view entry] [view interactions] Low throughput yes yes
NDK5_HUMAN [view interactions] Low throughput no yes
RELB_HUMAN [view interactions] Low throughput no yes
CTNB1_HUMAN [view entry] [view interactions] Low throughput yes yes
KAT2A_HUMAN [view interactions] Low throughput no no
SIR2_HUMAN [view entry] [view interactions] Low throughput yes yes
RUVB2_HUMAN [view interactions] Low throughput no yes
CDC20_HUMAN [view interactions] Low throughput no no
FOXP3_HUMAN [view interactions] Low throughput no no
APC11_HUMAN [view interactions] Low throughput no yes
ELF3_HUMAN [view interactions] Low throughput no no
FBXW2_HUMAN [view interactions] Low throughput no yes
KDM2A_HUMAN [view interactions] Low throughput no yes
NSD1_HUMAN [view interactions] Low throughput no yes
CRIP2_HUMAN [view entry] [view interactions] Low throughput yes no
CTNA1_HUMAN [view entry] [view interactions] Low throughput yes yes
NEMO_HUMAN [view interactions] Low throughput no yes
CARM1_HUMAN [view interactions] Low throughput no yes
TADBP_HUMAN [view interactions] Low throughput no yes
M4K1_HUMAN [view interactions] Low throughput no no
TNR6_HUMAN [view interactions] Low throughput no no
RORA_HUMAN [view interactions] Low throughput no yes
UBAC1_HUMAN [view interactions] Low throughput no yes
TLR2_HUMAN [view interactions] Low throughput no no
YAP1_HUMAN [view interactions] Low throughput no yes
BAF_HUMAN [view entry] [view interactions] Low throughput yes yes
HOIL1_HUMAN [view interactions] Low throughput no no
KPCZ_HUMAN [view entry] [view interactions] Low throughput yes yes
IKKB_HUMAN [view interactions] Low throughput no yes
RN182_HUMAN [view interactions] Low throughput no no
OVOL2_HUMAN [view interactions] Low throughput no no
ANXA2_HUMAN [view entry] [view interactions] Low throughput yes no
DCAF1_HUMAN [view interactions] Low throughput no yes
IMA1_HUMAN [view entry] [view interactions] Low throughput yes yes
MRTFA_HUMAN [view entry] [view interactions] Low throughput yes yes
MDM2_HUMAN [view entry] [view interactions] Low throughput yes yes
ANDR_HUMAN [view interactions] Low throughput no no
CITE2_HUMAN [view interactions] Low throughput no yes
TRIP4_HUMAN [view interactions] Low throughput no yes
TFAP4_HUMAN [view interactions] Low throughput no yes
HMGA2_HUMAN [view interactions] Low throughput no yes
HEXI1_HUMAN [view interactions] Low throughput no yes
PP2AB_HUMAN [view interactions] Low throughput no yes
SRF_HUMAN [view interactions] Low throughput no yes
PPARA_HUMAN [view interactions] Low throughput no yes
PRGR_HUMAN [view interactions] Low throughput no no
NKRF_HUMAN [view interactions] Low throughput no no
PP4C_HUMAN [view interactions] Low throughput no yes
TAF1_HUMAN [view interactions] Low throughput no yes
TAF6_HUMAN [view interactions] Low throughput no no
TAF11_HUMAN [view interactions] Low throughput no no
TAF4B_HUMAN [view interactions] Low throughput no yes
EGR1_HUMAN [view interactions] Low throughput no yes
CEBPD_HUMAN [view interactions] Low throughput no no
IRF8_HUMAN [view interactions] Low throughput no no
IRF2_HUMAN [view interactions] Low throughput no yes
IRF9_HUMAN [view interactions] Low throughput no yes
SNIP1_HUMAN [view interactions] Low throughput no no
TAF9_HUMAN [view interactions] Low throughput no yes
MED15_HUMAN [view interactions] Low throughput no yes
GCR_HUMAN [view entry] [view interactions] Low throughput yes yes
MED23_HUMAN [view interactions] Low throughput no no
CEBPB_HUMAN [view interactions] Low throughput no no
MED7_HUMAN [view interactions] Low throughput no no
SMCA2_HUMAN [view interactions] Low throughput no yes
PLK1_HUMAN [view interactions] Low throughput no yes
PK3CA_HUMAN [view entry] [view interactions] Low throughput yes yes
IKKE_HUMAN [view interactions] Low throughput no yes
UB2D1_HUMAN [view interactions] Low throughput no yes
HDAC2_HUMAN [view interactions] Low throughput no yes
UB2E1_HUMAN [view interactions] Low throughput no yes
RXRA_HUMAN [view interactions] Low throughput no yes
UBE2H_HUMAN [view interactions] Low throughput no yes
UB2R1_HUMAN [view interactions] Low throughput no yes
PRGC1_HUMAN [view interactions] Low throughput no no
UB2D2_HUMAN [view interactions] Low throughput no yes
UB2D3_HUMAN [view interactions] Low throughput no yes
CENPJ_HUMAN [view interactions] Low throughput no no
UB2L3_HUMAN [view interactions] Low throughput no yes
UBE2C_HUMAN [view interactions] Low throughput no yes
CHK1_HUMAN [view interactions] Low throughput no no
JUN_HUMAN [view interactions] Low throughput no yes
PIAS3_HUMAN [view entry] [view interactions] Low throughput yes yes
RNF25_HUMAN [view interactions] Low throughput no no
IASPP_HUMAN [view interactions] Low throughput no yes
ING4_HUMAN [view interactions] Low throughput no no
NCOR2_HUMAN [view interactions] Low throughput no yes
APBA2_HUMAN [view interactions] Low throughput no yes
TLE5_HUMAN [view interactions] Low throughput no no
KAT5_HUMAN [view interactions] Low throughput no yes
ZBT7A_HUMAN [view interactions] Low throughput no yes
HSF1_HUMAN [view interactions] Low throughput no yes
RPB1_HUMAN [view interactions] Low throughput no no
PPARG_HUMAN [view interactions] Low throughput no yes
ATM_HUMAN [view interactions] Low throughput no yes
DNM3B_HUMAN [view interactions] Low throughput no yes
AP2A_HUMAN [view interactions] Low throughput no no
TOM20_HUMAN [view entry] [view interactions] Low throughput yes yes
MEOX2_HUMAN [view interactions] Low throughput no no
BANP_HUMAN [view interactions] Low throughput no yes
TNIP2_HUMAN [view interactions] Low throughput no yes
TBK1_HUMAN [view entry] [view interactions] Low throughput yes yes
BARD1_HUMAN [view interactions] Low throughput no yes
BRCA1_HUMAN [view interactions] Low throughput no yes
UN5CL_HUMAN [view interactions] Low throughput no no
TRIB3_HUMAN [view interactions] Low throughput no yes
HMGB1_HUMAN [view interactions] Low throughput no yes
CSK22_HUMAN [view entry] [view interactions] Low throughput yes no
CDK9_HUMAN [view interactions] Low throughput no yes
PML_HUMAN [view interactions] Low throughput no yes
NOTC1_HUMAN [view entry] [view interactions] Low throughput yes yes
ETHE1_HUMAN [view interactions] Low throughput no yes
AHR_HUMAN [view interactions] Low throughput no yes
CENPR_HUMAN [view interactions] Low throughput no yes
TERT_HUMAN [view interactions] Low throughput no no
RFC1_HUMAN [view interactions] Low throughput no yes
FBW1A_HUMAN [view interactions] Low throughput no yes
CUL1_HUMAN [view interactions] High throughput no yes
DYHC1_HUMAN [view entry] [view interactions] High throughput yes yes
NUMA1_HUMAN [view interactions] High throughput no yes
GAPD1_HUMAN [view entry] [view interactions] High throughput yes yes
SMAD2_HUMAN [view interactions] High throughput no yes
ZFHX3_HUMAN [view interactions] High throughput no yes
SNF8_HUMAN [view interactions] High throughput no yes
RBM14_HUMAN [view interactions] High throughput no yes
NAA15_HUMAN [view interactions] High throughput no yes
RPA49_HUMAN [view interactions] High throughput no yes
RPA2_HUMAN [view interactions] High throughput no no
INT13_HUMAN [view interactions] High throughput no no
NGAP_HUMAN [view entry] [view interactions] High throughput yes yes
PP6R1_HUMAN [view interactions] High throughput no no
HOOK1_HUMAN [view interactions] High throughput no no
HOOK3_HUMAN [view entry] [view interactions] High throughput yes yes
SAR1A_HUMAN [view entry] [view interactions] High throughput yes yes
CCNF_HUMAN [view interactions] High throughput no no
KTI12_HUMAN [view interactions] High throughput no yes
AFF1_HUMAN [view interactions] High throughput no no
TGON2_HUMAN [view entry] [view interactions] High throughput yes yes
FBW1B_HUMAN [view interactions] High throughput no yes
DCD_HUMAN [view interactions] High throughput no no
K2C5_HUMAN [view entry] [view interactions] High throughput yes no
BIP_HUMAN [view entry] [view interactions] High throughput yes yes
POTEJ_HUMAN [view interactions] High throughput no no
IL1RA_HUMAN [view interactions] High throughput no no
DHSO_HUMAN [view interactions] High throughput no no
POTEE_HUMAN [view interactions] High throughput no no
RBTN2_HUMAN [view interactions] High throughput no yes
PLMN_HUMAN [view interactions] High throughput no no
SRSF7_HUMAN [view interactions] High throughput no yes
DI3L2_HUMAN [view interactions] High throughput no yes
MK10_HUMAN [view entry] [view interactions] High throughput yes yes
GAN_HUMAN [view interactions] High throughput no yes
SOCS6_HUMAN [view interactions] High throughput no yes
PRKDC_HUMAN [view entry] [view interactions] High throughput yes yes
PIWL4_HUMAN [view interactions] High throughput no yes
CNNM3_HUMAN [view interactions] High throughput no yes
ABCA1_HUMAN [view interactions] High throughput no yes
MK14_HUMAN [view interactions] High throughput no yes
S31A3_HUMAN [view interactions] High throughput no no
RL13_HUMAN [view entry] [view interactions] High throughput yes yes
PEX1_HUMAN [view interactions] High throughput no no
PA24A_HUMAN [view entry] [view interactions] High throughput yes yes
REV1_HUMAN [view interactions] High throughput no yes
CDK4_HUMAN [view interactions] High throughput no no
CCND1_HUMAN [view interactions] High throughput no yes
RING2_HUMAN [view interactions] High throughput no yes
CCN3_HUMAN [view interactions] High throughput no no
NTRK1_HUMAN [view interactions] High throughput no yes
WASP_HUMAN [view interactions] High throughput no yes
HIF1N_HUMAN [view interactions] High throughput no yes
HERC3_HUMAN [view interactions] High throughput no yes
EGLN3_HUMAN [view interactions] High throughput no no
PSMD4_HUMAN [view interactions] High throughput no yes
PRS7_HUMAN [view interactions] High throughput no yes
HYPK_HUMAN [view interactions] High throughput no no
NUFP2_HUMAN [view interactions] High throughput no no
CD006_HUMAN [view interactions] High throughput no no
TIM8A_HUMAN [view interactions] High throughput no yes
TIM8B_HUMAN [view interactions] High throughput no yes
TIM13_HUMAN [view interactions] High throughput no yes
PHF10_HUMAN [view interactions] High throughput no yes
IMA4_HUMAN [view interactions] High throughput no yes
DPF1_HUMAN [view interactions] High throughput no yes
AP1G1_HUMAN [view entry] [view interactions] High throughput yes yes
NF2L2_HUMAN [view interactions] High throughput no yes
GPC4_HUMAN [view entry] [view interactions] High throughput yes yes
IMA5_HUMAN [view entry] [view interactions] High throughput yes yes
IMB1_HUMAN [view entry] [view interactions] High throughput yes yes
HSP76_HUMAN [view entry] [view interactions] High throughput yes yes
MK01_HUMAN [view entry] [view interactions] High throughput yes yes
SNX27_HUMAN [view entry] [view interactions] High throughput yes no
PTOV1_HUMAN [view interactions] High throughput no yes
PRPS1_HUMAN [view entry] [view interactions] High throughput yes no
IMA7_HUMAN [view interactions] High throughput no yes
COMD2_HUMAN [view interactions] High throughput no yes
GPC6_HUMAN [view entry] [view interactions] High throughput yes yes
WDR26_HUMAN [view interactions] High throughput no yes
COMD4_HUMAN [view interactions] High throughput no no
DECR_HUMAN [view entry] [view interactions] High throughput yes yes
COMD5_HUMAN [view interactions] High throughput no no
SKI8_HUMAN [view interactions] High throughput no yes
COMD8_HUMAN [view interactions] High throughput no yes
DNJB6_HUMAN [view entry] [view interactions] High throughput yes yes
GSLG1_HUMAN [view entry] [view interactions] High throughput yes yes
COMD7_HUMAN [view interactions] High throughput no no
SAHH2_HUMAN [view entry] [view interactions] High throughput yes yes
HSP72_HUMAN [view entry] [view interactions] High throughput yes no
LRC66_HUMAN [view interactions] High throughput no no
ATX3_HUMAN [view interactions] High throughput no yes
XPO1_HUMAN [view entry] [view interactions] High throughput yes yes
ACTN4_HUMAN [view entry] [view interactions] High throughput yes yes
CTBP2_HUMAN [view interactions] High throughput no no
KIF14_HUMAN [view interactions] High throughput no no
RIGI_HUMAN [view interactions] High throughput no yes
PAXX_HUMAN [view interactions] High throughput no yes
CB27A_HUMAN [view interactions] High throughput no no
CB27B_HUMAN [view interactions] High throughput no no
PXDC2_HUMAN [view interactions] High throughput no yes
BAG2_HUMAN [view entry] [view interactions] High throughput yes no
DAPP1_HUMAN [view interactions] High throughput no yes
CLH2_HUMAN [view interactions] High throughput no no
PIP_HUMAN [view interactions] High throughput no no
EFMT3_HUMAN [view interactions] High throughput no no
DCTN3_HUMAN [view entry] [view interactions] High throughput yes yes
ACTN1_HUMAN [view entry] [view interactions] High throughput yes yes
RPN1_HUMAN [view entry] [view interactions] High throughput yes yes
AL3A2_HUMAN [view entry] [view interactions] High throughput yes yes
ATAD1_HUMAN [view entry] [view interactions] High throughput yes yes
CK5P2_HUMAN [view interactions] High throughput no yes
MTSS1_HUMAN [view interactions] High throughput no no
FA20C_HUMAN [view interactions] High throughput no no
C1QB_HUMAN [view entry] [view interactions] High throughput yes no
PRKN_HUMAN [view entry] [view interactions] High throughput yes yes
CO2A1_HUMAN [view interactions] High throughput no no
ZRAN1_HUMAN [view interactions] High throughput no yes
DDC_HUMAN [view interactions] High throughput no no
EF1D_HUMAN [view entry] [view interactions] High throughput yes yes
ISL1_HUMAN [view interactions] High throughput no no
TRI67_HUMAN [view interactions] High throughput no no
RPN2_HUMAN [view entry] [view interactions] High throughput yes yes
SMAD3_HUMAN [view interactions] High throughput no yes
SMAD4_HUMAN [view interactions] High throughput no yes
ATX1_HUMAN [view interactions] High throughput no yes
KPYM_HUMAN [view interactions] High throughput no yes
RNAS1_HUMAN [view interactions] High throughput no yes
MPIP1_HUMAN [view interactions] High throughput no no
SAT1_HUMAN [view interactions] High throughput no yes
PTPRJ_HUMAN [view interactions] High throughput no yes
CCL5_HUMAN [view interactions] High throughput no no
KITH_HUMAN [view interactions] High throughput no yes
RU17_HUMAN [view interactions] High throughput no yes
KDM1A_HUMAN [view interactions] High throughput no yes
TELT_HUMAN [view interactions] High throughput no no
PNMT_HUMAN [view interactions] High throughput no no
RL23_HUMAN [view entry] [view interactions] High throughput yes yes
ATG12_HUMAN [view interactions] High throughput no yes
MSH2_HUMAN [view interactions] High throughput no yes
AGO1_HUMAN [view interactions] High throughput no no
FKB11_HUMAN [view interactions] High throughput no no
NCOA6_HUMAN [view interactions] High throughput no yes
RIOK2_HUMAN [view interactions] High throughput no yes
GOPC_HUMAN [view entry] [view interactions] High throughput yes yes
BATF2_HUMAN [view interactions] High throughput no yes
CASP6_HUMAN [view interactions] High throughput no no
CCKN_HUMAN [view interactions] High throughput no yes
FGFR3_HUMAN [view interactions] High throughput no yes
GELS_HUMAN [view entry] [view interactions] High throughput yes no
RAN_HUMAN [view entry] [view interactions] High throughput yes no
UBQL1_HUMAN [view interactions] High throughput no yes
DNMT1_HUMAN [view interactions] High throughput no no
SRBP1_HUMAN [view interactions] High throughput no yes
PANKY_HUMAN [view interactions] High throughput no no
ZDH13_HUMAN [view interactions] High throughput no no
ZMY11_HUMAN [view interactions] High throughput no no
ANKR7_HUMAN [view interactions] High throughput no no
CXXC1_HUMAN [view interactions] High throughput no yes
CERS2_HUMAN [view interactions] High throughput no no
BRPF1_HUMAN [view interactions] High throughput no yes
USF2_HUMAN [view interactions] High throughput no no
RAB21_HUMAN [view entry] [view interactions] High throughput yes yes
MP2K6_HUMAN [view interactions] High throughput no yes
HS71L_HUMAN [view entry] [view interactions] High throughput yes no
M3K7_HUMAN [view interactions] High throughput no yes
STAT1_HUMAN [view entry] [view interactions] High throughput yes no
MKS1_HUMAN [view interactions] High throughput no no
SSH3_HUMAN [view interactions] High throughput no yes
CFTR_HUMAN [view interactions] High throughput no no
EPHA2_HUMAN [view interactions] High throughput no no
GLIS1_HUMAN [view interactions] High throughput no no
NFIC_HUMAN [view interactions] High throughput no yes
RASF1_HUMAN [view interactions] High throughput no yes
ARNT_HUMAN [view entry] [view interactions] High throughput yes yes
AURKA_HUMAN [view entry] [view interactions] High throughput yes no
CCND2_HUMAN [view interactions] High throughput no yes
IGF1R_HUMAN [view entry] [view interactions] High throughput yes yes
LATS2_HUMAN [view interactions] High throughput no yes
ITF2_HUMAN [view interactions] High throughput no yes
MX1_HUMAN [view interactions] High throughput no yes
ICAM1_HUMAN [view interactions] High throughput no no
ASB9_HUMAN [view interactions] High throughput no no
SMD3_HUMAN [view interactions] High throughput no yes
PO6F2_HUMAN [view interactions] High throughput no no
DDX3X_HUMAN [view entry] [view interactions] High throughput yes yes
RT4I1_HUMAN [view interactions] High throughput no yes
PPP6_HUMAN [view interactions] High throughput no yes
SUOX_HUMAN [view interactions] High throughput no no
SC16A_HUMAN [view interactions] High throughput no yes
ANR28_HUMAN [view interactions] High throughput no no
TRI55_HUMAN [view interactions] High throughput no no
RPA34_HUMAN [view interactions] High throughput no yes
TRI63_HUMAN [view interactions] High throughput no no
DC1L2_HUMAN [view entry] [view interactions] High throughput yes yes
IQGA2_HUMAN [view interactions] High throughput no yes
JIP4_HUMAN [view interactions] High throughput no yes
AKP8L_HUMAN [view interactions] High throughput no yes
ANM3_HUMAN [view interactions] High throughput no yes
MTA2_HUMAN [view interactions] High throughput no yes
ELP1_HUMAN [view interactions] High throughput no yes
RPA1_HUMAN [view interactions] High throughput no yes
XRCC6_HUMAN [view interactions] High throughput no yes
TYY1_HUMAN [view interactions] High throughput no yes
COPB2_HUMAN [view entry] [view interactions] High throughput yes yes
ODO2_HUMAN [view entry] [view interactions] High throughput yes yes
LPPRC_HUMAN [view entry] [view interactions] High throughput yes yes
IF2M_HUMAN [view interactions] High throughput no yes
PAPOA_HUMAN [view interactions] High throughput no yes
RPAB3_HUMAN [view interactions] High throughput no yes
TCP4_HUMAN [view interactions] High throughput no yes
RL30_HUMAN [view entry] [view interactions] High throughput yes yes
SKP1_HUMAN [view interactions] High throughput no yes
GTF2I_HUMAN [view interactions] High throughput no yes
CAP1_HUMAN [view entry] [view interactions] High throughput yes yes
RL6_HUMAN [view entry] [view interactions] High throughput yes yes