ARNT_HUMAN
Evidence for PS localization
Functions
Required for activity of the Ah (dioxin) receptor. This protein is required for the ligand-binding subunit to translocate from the cytosol to the nucleus after ligand binding. The complex then initiates transcription of genes involved in the activation of PAH procarcinogens. The heterodimer binds to core DNA sequence 5-TACGTG-3 within the hypoxia response element (HRE) of target gene promoters and functions as a transcriptional regulator of the adaptive response to hypoxia . The heterodimer ARNT:AHR binds to core DNA sequence 5-TGCGTG-3 within the dioxin response element (DRE) of target gene promoters and activates their transcription (PubMed). [View more on UniProt]
Protein features
Binary interactions with known binding regions
To display all evidence describing the interaction with a partner, click on the protein name left to the bars.
Network
Isoforms
Disease-causing germline mutations
No data found.
Linear motifs
| ELM instance | Name | Type | Start | End | Partner |
|---|---|---|---|---|---|
| ELMI000851 | MOD_SUMO_for_1 | MOD | 244 | 247 | - |
| ELMI000851 | MOD_SUMO_for_1 | MOD | 244 | 247 | - |
Fingerprint
Molecular function
| Term | Name | % | Distance from the top of the tree | Annotated in ARNT_HUMAN |
|---|---|---|---|---|
| GO:0043168 | anion binding | 39.5062 | 4 | no |
| GO:0000166 | nucleotide binding | 34.5679 | 4 | no |
| GO:0017076 | purine nucleotide binding | 34.5679 | 5 | no |
| GO:0032555 | purine ribonucleotide binding | 34.5679 | 4 | no |
| GO:0035639 | purine ribonucleoside triphosphate binding | 34.5679 | 4 | no |
| GO:0003723 | RNA binding | 28.3951 | 4 | no |
| GO:0043169 | cation binding | 27.1605 | 4 | no |
| GO:0046872 | metal ion binding | 27.1605 | 5 | no |
| GO:0005524 | ATP binding | 25.9259 | 5 | no |
| GO:0030554 | adenyl nucleotide binding | 25.9259 | 6 | no |
| GO:0032559 | adenyl ribonucleotide binding | 25.9259 | 5 | no |
| GO:0042803 | protein homodimerization activity | 13.5802 | 4 | yes |
| GO:0140297 | DNA-binding transcription factor binding | 12.3457 | 4 | yes |
| GO:0003677 | DNA binding | 8.6420 | 4 | yes |
| GO:0061629 | RNA polymerase II-specific DNA-binding transcription factor binding | 8.6420 | 5 | yes |
| GO:0003690 | double-stranded DNA binding | 7.4074 | 5 | yes |
| GO:0043565 | sequence-specific DNA binding | 6.1728 | 5 | yes |
| GO:1990837 | sequence-specific double-stranded DNA binding | 6.1728 | 6 | yes |
| GO:0000976 | transcription cis-regulatory region binding | 4.9383 | 5 | yes |
| GO:0000977 | RNA polymerase II transcription regulatory region sequence-specific DNA binding | 4.9383 | 6 | yes |
| GO:0000978 | RNA polymerase II cis-regulatory region sequence-specific DNA binding | 4.9383 | 7 | yes |
| GO:0000987 | cis-regulatory region sequence-specific DNA binding | 4.9383 | 6 | yes |
| GO:0001067 | transcription regulatory region nucleic acid binding | 4.9383 | 4 | yes |
| GO:0046982 | protein heterodimerization activity | 4.9383 | 4 | yes |
| GO:0017162 | aryl hydrocarbon receptor binding | 3.7037 | 4 | yes |
Biological process
| Term | Name | % | Distance from top the of the tree | Annotated in ARNT_HUMAN |
|---|---|---|---|---|
| GO:0048522 | positive regulation of cellular process | 66.6667 | 4 | yes |
| GO:0031323 | regulation of cellular metabolic process | 60.4938 | 4 | yes |
| GO:0060255 | regulation of macromolecule metabolic process | 60.4938 | 4 | yes |
| GO:0080090 | regulation of primary metabolic process | 58.0247 | 4 | yes |
| GO:0009893 | positive regulation of metabolic process | 53.0864 | 4 | yes |
| GO:0009889 | regulation of biosynthetic process | 51.8519 | 4 | yes |
| GO:0010468 | regulation of gene expression | 51.8519 | 6 | yes |
| GO:0010556 | regulation of macromolecule biosynthetic process | 51.8519 | 5 | yes |
| GO:0010604 | positive regulation of macromolecule metabolic process | 51.8519 | 5 | yes |
| GO:0031326 | regulation of cellular biosynthetic process | 51.8519 | 5 | yes |
| GO:0010646 | regulation of cell communication | 50.6173 | 4 | yes |
| GO:0031325 | positive regulation of cellular metabolic process | 50.6173 | 5 | yes |
| GO:0009966 | regulation of signal transduction | 48.1481 | 4 | yes |
| GO:0048523 | negative regulation of cellular process | 45.6790 | 4 | no |
| GO:0051246 | regulation of protein metabolic process | 44.4444 | 5 | yes |
| GO:0009891 | positive regulation of biosynthetic process | 39.5062 | 5 | yes |
| GO:0010557 | positive regulation of macromolecule biosynthetic process | 39.5062 | 6 | yes |
| GO:0031328 | positive regulation of cellular biosynthetic process | 39.5062 | 6 | yes |
| GO:0048584 | positive regulation of response to stimulus | 38.2716 | 4 | yes |
| GO:0051128 | regulation of cellular component organization | 37.0370 | 4 | no |
| GO:0042981 | regulation of apoptotic process | 35.8025 | 5 | no |
| GO:0043067 | regulation of programmed cell death | 35.8025 | 4 | no |
| GO:1902531 | regulation of intracellular signal transduction | 35.8025 | 5 | no |
| GO:0019219 | regulation of nucleobase-containing compound metabolic process | 35.8025 | 5 | yes |
| GO:0051247 | positive regulation of protein metabolic process | 35.8025 | 6 | yes |
| GO:0010647 | positive regulation of cell communication | 34.5679 | 5 | yes |
| GO:0023056 | positive regulation of signaling | 34.5679 | 4 | yes |
| GO:0009967 | positive regulation of signal transduction | 33.3333 | 5 | yes |
| GO:0051252 | regulation of RNA metabolic process | 33.3333 | 5 | yes |
| GO:0031399 | regulation of protein modification process | 32.0988 | 6 | yes |
| GO:2001141 | regulation of RNA biosynthetic process | 30.8642 | 6 | yes |
| GO:0009892 | negative regulation of metabolic process | 30.8642 | 4 | no |
| GO:0010605 | negative regulation of macromolecule metabolic process | 30.8642 | 5 | no |
| GO:0006355 | regulation of DNA-templated transcription | 30.8642 | 7 | yes |
| GO:0010628 | positive regulation of gene expression | 28.3951 | 7 | yes |
| GO:0006996 | organelle organization | 27.1605 | 4 | no |
| GO:0008104 | protein localization | 27.1605 | 4 | no |
| GO:0045935 | positive regulation of nucleobase-containing compound metabolic process | 27.1605 | 5 | yes |
| GO:0051240 | positive regulation of multicellular organismal process | 27.1605 | 4 | yes |
| GO:0031324 | negative regulation of cellular metabolic process | 25.9259 | 5 | no |
| GO:0019220 | regulation of phosphate metabolic process | 25.9259 | 6 | yes |
| GO:0042127 | regulation of cell population proliferation | 25.9259 | 4 | yes |
| GO:0051174 | regulation of phosphorus metabolic process | 25.9259 | 5 | yes |
| GO:0051248 | negative regulation of protein metabolic process | 24.6914 | 6 | no |
| GO:0048585 | negative regulation of response to stimulus | 24.6914 | 4 | yes |
| GO:0051254 | positive regulation of RNA metabolic process | 24.6914 | 6 | yes |
| GO:0001932 | regulation of protein phosphorylation | 23.4568 | 7 | no |
| GO:0042325 | regulation of phosphorylation | 23.4568 | 7 | no |
| GO:0043066 | negative regulation of apoptotic process | 23.4568 | 6 | no |
| GO:0043069 | negative regulation of programmed cell death | 23.4568 | 5 | no |
| GO:2000026 | regulation of multicellular organismal development | 22.2222 | 4 | yes |
| GO:0006796 | phosphate-containing compound metabolic process | 22.2222 | 4 | no |
| GO:0043412 | macromolecule modification | 22.2222 | 4 | no |
| GO:0071310 | cellular response to organic substance | 22.2222 | 4 | no |
| GO:0051049 | regulation of transport | 22.2222 | 4 | no |
| GO:0045595 | regulation of cell differentiation | 22.2222 | 4 | yes |
| GO:0045893 | positive regulation of DNA-templated transcription | 22.2222 | 8 | yes |
| GO:1902680 | positive regulation of RNA biosynthetic process | 22.2222 | 7 | yes |
| GO:0009968 | negative regulation of signal transduction | 20.9877 | 5 | no |
| GO:0010648 | negative regulation of cell communication | 20.9877 | 5 | no |
| GO:0022607 | cellular component assembly | 20.9877 | 4 | no |
| GO:0023057 | negative regulation of signaling | 20.9877 | 4 | no |
| GO:0036211 | protein modification process | 20.9877 | 4 | no |
| GO:0043933 | protein-containing complex organization | 20.9877 | 4 | no |
| GO:0071702 | organic substance transport | 20.9877 | 4 | no |
| GO:1902533 | positive regulation of intracellular signal transduction | 20.9877 | 6 | no |
| GO:0009894 | regulation of catabolic process | 20.9877 | 4 | yes |
| GO:0010562 | positive regulation of phosphorus metabolic process | 20.9877 | 6 | yes |
| GO:0031401 | positive regulation of protein modification process | 20.9877 | 7 | yes |
| GO:0032101 | regulation of response to external stimulus | 20.9877 | 4 | yes |
| GO:0045937 | positive regulation of phosphate metabolic process | 20.9877 | 7 | yes |
| GO:0051094 | positive regulation of developmental process | 20.9877 | 4 | yes |
| GO:0080134 | regulation of response to stress | 20.9877 | 4 | yes |
| GO:0001817 | regulation of cytokine production | 19.7531 | 4 | yes |
| GO:0006357 | regulation of transcription by RNA polymerase II | 19.7531 | 8 | yes |
| GO:0031347 | regulation of defense response | 17.2840 | 5 | yes |
| GO:0045944 | positive regulation of transcription by RNA polymerase II | 17.2840 | 9 | yes |
| GO:0045597 | positive regulation of cell differentiation | 16.0494 | 5 | yes |
| GO:0060284 | regulation of cell development | 16.0494 | 5 | yes |
| GO:0001819 | positive regulation of cytokine production | 14.8148 | 5 | yes |
| GO:0008284 | positive regulation of cell population proliferation | 14.8148 | 5 | yes |
| GO:1901873 | regulation of post-translational protein modification | 12.3457 | 7 | yes |
| GO:1903320 | regulation of protein modification by small protein conjugation or removal | 12.3457 | 8 | yes |
| GO:0050678 | regulation of epithelial cell proliferation | 11.1111 | 5 | yes |
| GO:1903706 | regulation of hemopoiesis | 9.8765 | 4 | yes |
| GO:0036293 | response to decreased oxygen levels | 9.8765 | 4 | yes |
| GO:0009896 | positive regulation of catabolic process | 8.6420 | 5 | yes |
| GO:0031329 | regulation of cellular catabolic process | 8.6420 | 5 | yes |
| GO:0045637 | regulation of myeloid cell differentiation | 8.6420 | 5 | yes |
| GO:0050679 | positive regulation of epithelial cell proliferation | 8.6420 | 6 | yes |
| GO:0050727 | regulation of inflammatory response | 8.6420 | 5 | yes |
| GO:0045646 | regulation of erythrocyte differentiation | 7.4074 | 6 | yes |
| GO:0090287 | regulation of cellular response to growth factor stimulus | 7.4074 | 4 | yes |
| GO:0031348 | negative regulation of defense response | 6.1728 | 5 | yes |
| GO:0032102 | negative regulation of response to external stimulus | 6.1728 | 5 | yes |
| GO:0045639 | positive regulation of myeloid cell differentiation | 6.1728 | 6 | yes |
| GO:0045648 | positive regulation of erythrocyte differentiation | 6.1728 | 7 | yes |
| GO:0050728 | negative regulation of inflammatory response | 6.1728 | 6 | yes |
| GO:0001936 | regulation of endothelial cell proliferation | 4.9383 | 6 | yes |
| GO:0001938 | positive regulation of endothelial cell proliferation | 4.9383 | 7 | yes |
| GO:0006109 | regulation of carbohydrate metabolic process | 4.9383 | 5 | yes |
| GO:0010574 | regulation of vascular endothelial growth factor production | 4.9383 | 5 | yes |
| GO:0010575 | positive regulation of vascular endothelial growth factor production | 4.9383 | 6 | yes |
| GO:0033233 | regulation of protein sumoylation | 4.9383 | 9 | yes |
| GO:0043467 | regulation of generation of precursor metabolites and energy | 4.9383 | 5 | yes |
| GO:0048568 | embryonic organ development | 4.9383 | 4 | yes |
| GO:0043470 | regulation of carbohydrate catabolic process | 3.7037 | 5 | yes |
| GO:0045913 | positive regulation of carbohydrate metabolic process | 3.7037 | 5 | yes |
| GO:0062012 | regulation of small molecule metabolic process | 3.7037 | 4 | yes |
| GO:0062013 | positive regulation of small molecule metabolic process | 3.7037 | 5 | yes |
| GO:0001892 | embryonic placenta development | 2.4691 | 5 | yes |
| GO:0006110 | regulation of glycolytic process | 2.4691 | 6 | yes |
| GO:0006140 | regulation of nucleotide metabolic process | 2.4691 | 5 | yes |
| GO:0030811 | regulation of nucleotide catabolic process | 2.4691 | 5 | yes |
| GO:0030813 | positive regulation of nucleotide catabolic process | 2.4691 | 6 | yes |
| GO:0030947 | regulation of vascular endothelial growth factor receptor signaling pathway | 2.4691 | 5 | yes |
| GO:0030949 | positive regulation of vascular endothelial growth factor receptor signaling pathway | 2.4691 | 6 | yes |
| GO:0031331 | positive regulation of cellular catabolic process | 2.4691 | 6 | yes |
| GO:0032350 | regulation of hormone metabolic process | 2.4691 | 4 | yes |
| GO:0032352 | positive regulation of hormone metabolic process | 2.4691 | 5 | yes |
| GO:0033121 | regulation of purine nucleotide catabolic process | 2.4691 | 6 | yes |
| GO:0033123 | positive regulation of purine nucleotide catabolic process | 2.4691 | 7 | yes |
| GO:0033235 | positive regulation of protein sumoylation | 2.4691 | 10 | yes |
| GO:0045821 | positive regulation of glycolytic process | 2.4691 | 6 | yes |
| GO:0045981 | positive regulation of nucleotide metabolic process | 2.4691 | 6 | yes |
| GO:0046885 | regulation of hormone biosynthetic process | 2.4691 | 5 | yes |
| GO:0046886 | positive regulation of hormone biosynthetic process | 2.4691 | 6 | yes |
| GO:1900542 | regulation of purine nucleotide metabolic process | 2.4691 | 6 | yes |
| GO:1900544 | positive regulation of purine nucleotide metabolic process | 2.4691 | 7 | yes |
| GO:1901875 | positive regulation of post-translational protein modification | 2.4691 | 8 | yes |
| GO:1903322 | positive regulation of protein modification by small protein conjugation or removal | 2.4691 | 9 | yes |
| GO:1903578 | regulation of ATP metabolic process | 2.4691 | 7 | yes |
| GO:1903580 | positive regulation of ATP metabolic process | 2.4691 | 8 | yes |
Disease
No data found.
All partners
| Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
|---|---|---|---|---|
| NEMO_HUMAN | [view interactions] | Low throughput | no | yes |
| HIF3A_HUMAN | [view interactions] | Low throughput | no | yes |
| TACC3_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| SDS3_HUMAN | [view interactions] | Low throughput | no | yes |
| MK04_HUMAN | [view interactions] | Low throughput | no | no |
| PRDX6_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| RAB35_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| TCTP_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| A1AG2_HUMAN | [view interactions] | Low throughput | no | no |
| A1AG1_HUMAN | [view interactions] | Low throughput | no | no |
| MED29_HUMAN | [view interactions] | Low throughput | no | no |
| TCAL6_HUMAN | [view interactions] | Low throughput | no | no |
| TCAL5_HUMAN | [view interactions] | Low throughput | no | no |
| MP2K3_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| DDB1_HUMAN | [view interactions] | Low throughput | no | yes |
| CUL4A_HUMAN | [view interactions] | Low throughput | no | no |
| CHD4_HUMAN | [view interactions] | Low throughput | no | yes |
| NPAS3_HUMAN | [view interactions] | Low throughput | no | yes |
| NANOG_HUMAN | [view interactions] | Low throughput | no | no |
| SP1_HUMAN | [view interactions] | Low throughput | no | yes |
| TEBP_HUMAN | [view interactions] | Low throughput | no | yes |
| AIP_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| T2FA_HUMAN | [view interactions] | Low throughput | no | yes |
| T2FB_HUMAN | [view interactions] | Low throughput | no | yes |
| PML_HUMAN | [view interactions] | Low throughput | no | yes |
| TBB2A_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| NR0B2_HUMAN | [view interactions] | Low throughput | no | no |
| ESR1_HUMAN | [view interactions] | Low throughput | no | no |
| CASP3_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| CASP9_HUMAN | [view interactions] | Low throughput | no | yes |
| TRIPB_HUMAN | [view interactions] | Low throughput | no | yes |
| VEGFA_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| LAT1_HUMAN | [view interactions] | Low throughput | no | yes |
| CP1B1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| AHR_HUMAN | [view interactions] | Low throughput | no | yes |
| SIM1_HUMAN | [view interactions] | Low throughput | no | no |
| SIM2_HUMAN | [view interactions] | Low throughput | no | yes |
| EPAS1_HUMAN | [view interactions] | Low throughput | no | no |
| CLOCK_HUMAN | [view interactions] | Low throughput | no | yes |
| ARNT_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| HIF1A_HUMAN | [view interactions] | Low throughput | no | no |
| HLF_HUMAN | [view interactions] | Low throughput | no | no |
| DCA15_HUMAN | [view interactions] | Low throughput | no | no |
| NPAS1_HUMAN | [view interactions] | Low throughput | no | no |
| NCOA7_HUMAN | [view interactions] | Low throughput | no | yes |
| NCOR2_HUMAN | [view interactions] | Low throughput | no | yes |
| FOXA2_HUMAN | [view interactions] | Low throughput | no | no |
| NPAS4_HUMAN | [view interactions] | Low throughput | no | yes |
| NCOA2_HUMAN | [view interactions] | Low throughput | no | no |
| NCOA1_HUMAN | [view interactions] | Low throughput | no | yes |
| AHRR_HUMAN | [view interactions] | Low throughput | no | no |
| HEY2_HUMAN | [view interactions] | Low throughput | no | no |
| HEY1_HUMAN | [view interactions] | Low throughput | no | yes |
| HNF4A_HUMAN | [view interactions] | Low throughput | no | no |
| NECD_HUMAN | [view interactions] | Low throughput | no | no |
| CEBPA_HUMAN | [view interactions] | Low throughput | no | yes |
| TRI59_HUMAN | [view interactions] | Low throughput | no | no |
| NPAS2_HUMAN | [view interactions] | Low throughput | no | yes |
| RB_HUMAN | [view interactions] | Low throughput | no | yes |
| BRCA1_HUMAN | [view interactions] | Low throughput | no | yes |
| CUL2_HUMAN | [view interactions] | Low throughput | no | yes |
| ELOB_HUMAN | [view interactions] | Low throughput | no | no |
| EP300_HUMAN | [view interactions] | Low throughput | no | yes |
| CACO1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| PIAS2_HUMAN | [view interactions] | Low throughput | no | yes |
| JUN_HUMAN | [view interactions] | Low throughput | no | yes |
| HS90A_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| AKT1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| TGM2_HUMAN | [view interactions] | Low throughput | no | no |
| CTNB1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| RL18_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DNJA2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| M2OM_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RANG_HUMAN | [view interactions] | High throughput | no | no |
| MYO1C_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CH60_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MATR3_HUMAN | [view interactions] | High throughput | no | yes |
| SI1L3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DPM1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CNBP_HUMAN | [view interactions] | High throughput | no | no |
| MPRIP_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PYR1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HMGB1_HUMAN | [view interactions] | High throughput | no | yes |
| ESR2_HUMAN | [view interactions] | High throughput | no | no |
| H4_HUMAN | [view interactions] | High throughput | no | yes |
| EGLN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CIC_HUMAN | [view interactions] | High throughput | no | yes |
| VHL_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ELOC_HUMAN | [view interactions] | High throughput | no | no |
| OR6K3_HUMAN | [view interactions] | High throughput | no | no |
| S10A8_HUMAN | [view interactions] | High throughput | no | no |
| S10A9_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| GIP_HUMAN | [view interactions] | High throughput | no | no |
| HSP72_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| SBP1_HUMAN | [view interactions] | High throughput | no | no |
| LYOX_HUMAN | [view interactions] | High throughput | no | no |
| CALL3_HUMAN | [view interactions] | High throughput | no | yes |
| TNNC2_HUMAN | [view interactions] | High throughput | no | no |
| NDOR1_HUMAN | [view interactions] | High throughput | no | yes |
| MD2L1_HUMAN | [view interactions] | High throughput | no | no |
| BAG2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| BOP_HUMAN | [view interactions] | High throughput | no | no |
| ZSC18_HUMAN | [view interactions] | High throughput | no | yes |
| FEM1A_HUMAN | [view interactions] | High throughput | no | no |
| TIM8A_HUMAN | [view interactions] | High throughput | no | yes |
| SHRPN_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PCCB_HUMAN | [view interactions] | High throughput | no | yes |
| PLAK_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ANDR_HUMAN | [view interactions] | High throughput | no | no |
| PARPT_HUMAN | [view interactions] | High throughput | no | no |
| FAS_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| TP4A3_HUMAN | [view interactions] | High throughput | no | no |
| EGFR_HUMAN | [view interactions] | High throughput | no | no |
| HAPR1_HUMAN | [view interactions] | High throughput | no | yes |
| IMA5_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| IMA4_HUMAN | [view interactions] | High throughput | no | yes |
| IMA6_HUMAN | [view interactions] | High throughput | no | yes |
| IMA7_HUMAN | [view interactions] | High throughput | no | yes |
| CCND2_HUMAN | [view interactions] | High throughput | no | yes |
| CCNE1_HUMAN | [view interactions] | High throughput | no | no |
| CDK4_HUMAN | [view interactions] | High throughput | no | no |
| CDK6_HUMAN | [view interactions] | High throughput | no | yes |
| CDN2B_HUMAN | [view interactions] | High throughput | no | no |
| EPHA2_HUMAN | [view interactions] | High throughput | no | no |
| FGFR4_HUMAN | [view interactions] | High throughput | no | no |
| STK11_HUMAN | [view interactions] | High throughput | no | yes |
| FZR1_HUMAN | [view interactions] | High throughput | no | no |
| MYC_HUMAN | [view interactions] | High throughput | no | yes |
| MERL_HUMAN | [view interactions] | High throughput | no | yes |
| CD44_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CDN2C_HUMAN | [view interactions] | High throughput | no | yes |
| ERBB2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| LATS2_HUMAN | [view interactions] | High throughput | no | yes |
| TEAD2_HUMAN | [view interactions] | High throughput | no | no |
| BECN1_HUMAN | [view interactions] | High throughput | no | yes |
| GLIS1_HUMAN | [view interactions] | High throughput | no | no |
| GLIS2_HUMAN | [view interactions] | High throughput | no | no |
| HGF_HUMAN | [view interactions] | High throughput | no | yes |
| MP2K5_HUMAN | [view interactions] | High throughput | no | yes |
| MK14_HUMAN | [view interactions] | High throughput | no | yes |
| PGFRA_HUMAN | [view interactions] | High throughput | no | no |
| RAF1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| TF65_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| P53_HUMAN | [view interactions] | High throughput | no | no |
| PDK1_HUMAN | [view interactions] | High throughput | no | yes |
| F263_HUMAN | [view interactions] | High throughput | no | yes |
| F264_HUMAN | [view interactions] | High throughput | no | no |
| LDHA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HXK1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PFKAM_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ICAM1_HUMAN | [view interactions] | High throughput | no | no |
| PRKDC_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ABT1_HUMAN | [view interactions] | High throughput | no | no |
| ARI5A_HUMAN | [view interactions] | High throughput | no | yes |
| FOS_HUMAN | [view interactions] | High throughput | no | yes |
| LDB2_HUMAN | [view interactions] | High throughput | no | yes |
| TEAD1_HUMAN | [view interactions] | High throughput | no | no |
| YAP1_HUMAN | [view interactions] | High throughput | no | yes |
| ARNT2_HUMAN | [view interactions] | High throughput | no | yes |
| DEAF1_HUMAN | [view interactions] | High throughput | no | yes |
| NR4A3_HUMAN | [view interactions] | High throughput | no | yes |
| NR6A1_HUMAN | [view interactions] | High throughput | no | no |
| RBL2_HUMAN | [view interactions] | High throughput | no | yes |
| SENP6_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SIN3A_HUMAN | [view interactions] | High throughput | no | yes |
| HTF4_HUMAN | [view interactions] | High throughput | no | yes |
| TF7L2_HUMAN | [view interactions] | High throughput | no | yes |
| AP2D_HUMAN | [view interactions] | High throughput | no | no |
| TFEB_HUMAN | [view interactions] | High throughput | no | no |
| WWTR1_HUMAN | [view interactions] | High throughput | no | yes |
| ZEB1_HUMAN | [view interactions] | High throughput | no | yes |
| SMG7_HUMAN | [view interactions] | High throughput | no | no |
| ASF1A_HUMAN | [view interactions] | High throughput | no | no |
| TE2IP_HUMAN | [view interactions] | High throughput | no | yes |
| SMAD9_HUMAN | [view interactions] | High throughput | no | yes |
| NUP35_HUMAN | [view interactions] | High throughput | no | yes |
| FOXO1_HUMAN | [view interactions] | High throughput | no | yes |
| IKBA_HUMAN | [view interactions] | High throughput | no | yes |
| SNR40_HUMAN | [view interactions] | High throughput | no | yes |
| TLE3_HUMAN | [view interactions] | High throughput | no | yes |
| RFA1_HUMAN | [view interactions] | High throughput | no | yes |
| BACD2_HUMAN | [view interactions] | High throughput | no | no |
| RFA3_HUMAN | [view interactions] | High throughput | no | yes |
| LSM8_HUMAN | [view interactions] | High throughput | no | yes |
| CRX_HUMAN | [view interactions] | High throughput | no | no |
| HIF1N_HUMAN | [view interactions] | High throughput | no | yes |
| GSC_HUMAN | [view interactions] | High throughput | no | no |
| EGLN3_HUMAN | [view interactions] | High throughput | no | no |
| EYA4_HUMAN | [view interactions] | High throughput | no | yes |
| BCAT1_HUMAN | [view interactions] | High throughput | no | no |
| CIAO3_HUMAN | [view interactions] | High throughput | no | yes |
| C1QT2_HUMAN | [view interactions] | High throughput | no | yes |
| FOXR2_HUMAN | [view interactions] | High throughput | no | no |
| SLX1_HUMAN | [view interactions] | High throughput | no | yes |
| HSP7C_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ERR1_HUMAN | [view interactions] | High throughput | no | yes |
| ERR2_HUMAN | [view interactions] | High throughput | no | no |
| ERR3_HUMAN | [view interactions] | High throughput | no | yes |
| KCNH2_HUMAN | [view interactions] | High throughput | no | no |
| ADHX_HUMAN | [view interactions] | High throughput | no | yes |
| GEMI_HUMAN | [view interactions] | High throughput | no | no |
| IRAK4_HUMAN | [view interactions] | High throughput | no | yes |
| STRBP_HUMAN | [view interactions] | High throughput | no | yes |
| DBLOH_HUMAN | [view interactions] | High throughput | no | no |
| MTA3_HUMAN | [view interactions] | High throughput | no | yes |
| CREB1_HUMAN | [view interactions] | High throughput | no | yes |
| FOXN1_HUMAN | [view interactions] | High throughput | no | no |
| FEV_HUMAN | [view interactions] | High throughput | no | no |
| PAX7_HUMAN | [view interactions] | High throughput | no | no |
| SOX2_HUMAN | [view interactions] | High throughput | no | yes |
| SOX6_HUMAN | [view interactions] | High throughput | no | yes |
| SP7_HUMAN | [view interactions] | High throughput | no | no |
| TLK2_HUMAN | [view interactions] | High throughput | no | no |
| ARL14_HUMAN | [view interactions] | High throughput | no | no |
| ELAV1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HERC2_HUMAN | [view interactions] | High throughput | no | yes |
| OSTM1_HUMAN | [view interactions] | High throughput | no | yes |
| GLYC_HUMAN | [view interactions] | High throughput | no | no |
| MYH10_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SPTB2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MYH9_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| SRC8_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CALM2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CALM3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CALM1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RAC1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| MYO1B_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| KLC1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| HSPB1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RL4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| 2AAA_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| GNAI2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RASK_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| 1433S_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PAXI_HUMAN | [view interactions] | High throughput | no | yes |
| DYN2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MYL6_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| HDAC1_HUMAN | [view interactions] | High throughput | no | no |
| CAND1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ARPC2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SMCA5_HUMAN | [view interactions] | High throughput | no | yes |
| LRC59_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GNAI1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RUVB2_HUMAN | [view interactions] | High throughput | no | yes |
| IPYR_HUMAN | [view interactions] | High throughput | no | yes |
| RL35A_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| FYN_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| TIF1B_HUMAN | [view interactions] | High throughput | no | yes |
| RTN4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NONO_HUMAN | [view interactions] | High throughput | no | yes |
| LAP2A_HUMAN | [view interactions] | High throughput | no | yes |
| SGT1_HUMAN | [view interactions] | High throughput | no | no |
| TENS3_HUMAN | [view interactions] | High throughput | no | no |
| XRCC6_HUMAN | [view interactions] | High throughput | no | yes |
| PUR8_HUMAN | [view interactions] | High throughput | no | yes |
| RL7_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RL19_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PP1A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PSMD2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CDK9_HUMAN | [view interactions] | High throughput | no | yes |
| H13_HUMAN | [view interactions] | High throughput | no | no |
| RUVB1_HUMAN | [view interactions] | High throughput | no | yes |
| RL27_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HS71B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HS71A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SYT7_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FLOT2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RS5_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LYN_HUMAN | [view entry] [view interactions] | High throughput | yes | no |