ARNT_HUMAN
Evidence for PS localization
Functions
Required for activity of the Ah (dioxin) receptor. This protein is required for the ligand-binding subunit to translocate from the cytosol to the nucleus after ligand binding. The complex then initiates transcription of genes involved in the activation of PAH procarcinogens. The heterodimer binds to core DNA sequence 5-TACGTG-3 within the hypoxia response element (HRE) of target gene promoters and functions as a transcriptional regulator of the adaptive response to hypoxia . The heterodimer ARNT:AHR binds to core DNA sequence 5-TGCGTG-3 within the dioxin response element (DRE) of target gene promoters and activates their transcription (PubMed). [View more on UniProt]
Protein features
Binary interactions with known binding regions
To display all evidence describing the interaction with a partner, click on the protein name left to the bars.
Network
Isoforms
Disease-causing germline mutations
No data found.
Linear motifs
| ELM instance | Name | Type | Start | End | Partner |
|---|---|---|---|---|---|
| ELMI000851 | MOD_SUMO_for_1 | MOD | 244 | 247 | - |
Fingerprint
Molecular function
| Term | Name | % | Distance from the top of the tree | Annotated in ARNT_HUMAN |
|---|---|---|---|---|
| GO:0017076 | purine nucleotide binding | 36.3636 | 4 | no |
| GO:0032555 | purine ribonucleotide binding | 35.0649 | 4 | no |
| GO:0035639 | purine ribonucleoside triphosphate binding | 35.0649 | 4 | no |
| GO:0003723 | RNA binding | 28.5714 | 4 | no |
| GO:0030554 | adenyl nucleotide binding | 27.2727 | 5 | no |
| GO:0005524 | ATP binding | 25.9740 | 5 | no |
| GO:0032559 | adenyl ribonucleotide binding | 25.9740 | 5 | no |
| GO:0046872 | metal ion binding | 24.6753 | 4 | no |
| GO:0045296 | cadherin binding | 20.7792 | 4 | no |
| GO:0042803 | protein homodimerization activity | 14.2857 | 4 | yes |
| GO:0140297 | DNA-binding transcription factor binding | 10.3896 | 4 | yes |
| GO:0003677 | DNA binding | 7.7922 | 4 | yes |
| GO:0061629 | RNA polymerase II-specific DNA-binding transcription factor binding | 7.7922 | 5 | yes |
| GO:0003690 | double-stranded DNA binding | 6.4935 | 5 | yes |
| GO:0043565 | sequence-specific DNA binding | 6.4935 | 5 | yes |
| GO:1990837 | sequence-specific double-stranded DNA binding | 6.4935 | 6 | yes |
| GO:0000976 | transcription cis-regulatory region binding | 5.1948 | 5 | yes |
| GO:0000977 | RNA polymerase II transcription regulatory region sequence-specific DNA binding | 5.1948 | 6 | yes |
| GO:0000978 | RNA polymerase II cis-regulatory region sequence-specific DNA binding | 5.1948 | 7 | yes |
| GO:0000987 | cis-regulatory region sequence-specific DNA binding | 5.1948 | 6 | yes |
| GO:0001067 | transcription regulatory region nucleic acid binding | 5.1948 | 4 | yes |
| GO:0046982 | protein heterodimerization activity | 5.1948 | 4 | yes |
| GO:0017162 | aryl hydrocarbon receptor binding | 3.8961 | 4 | yes |
Biological process
| Term | Name | % | Distance from top the of the tree | Annotated in ARNT_HUMAN |
|---|---|---|---|---|
| GO:0048522 | positive regulation of cellular process | 63.6364 | 4 | yes |
| GO:0060255 | regulation of macromolecule metabolic process | 61.0390 | 4 | yes |
| GO:0051171 | regulation of nitrogen compound metabolic process | 58.4416 | 4 | yes |
| GO:0080090 | regulation of primary metabolic process | 58.4416 | 4 | yes |
| GO:0031323 | regulation of cellular metabolic process | 54.5455 | 4 | yes |
| GO:0009893 | positive regulation of metabolic process | 51.9481 | 4 | yes |
| GO:0010646 | regulation of cell communication | 51.9481 | 4 | yes |
| GO:0010468 | regulation of gene expression | 50.6494 | 5 | yes |
| GO:0010604 | positive regulation of macromolecule metabolic process | 50.6494 | 5 | yes |
| GO:0009966 | regulation of signal transduction | 49.3506 | 4 | yes |
| GO:0051173 | positive regulation of nitrogen compound metabolic process | 45.4545 | 5 | yes |
| GO:0051246 | regulation of protein metabolic process | 44.1558 | 5 | yes |
| GO:0048523 | negative regulation of cellular process | 44.1558 | 4 | no |
| GO:0031325 | positive regulation of cellular metabolic process | 41.5584 | 5 | yes |
| GO:0009889 | regulation of biosynthetic process | 38.9610 | 4 | yes |
| GO:0031326 | regulation of cellular biosynthetic process | 38.9610 | 5 | yes |
| GO:0010556 | regulation of macromolecule biosynthetic process | 36.3636 | 5 | yes |
| GO:0019219 | regulation of nucleobase-containing compound metabolic process | 36.3636 | 5 | yes |
| GO:1902531 | regulation of intracellular signal transduction | 36.3636 | 5 | no |
| GO:0048584 | positive regulation of response to stimulus | 35.0649 | 4 | yes |
| GO:0010941 | regulation of cell death | 35.0649 | 4 | no |
| GO:0051128 | regulation of cellular component organization | 35.0649 | 4 | no |
| GO:0010647 | positive regulation of cell communication | 33.7662 | 5 | yes |
| GO:0023056 | positive regulation of signaling | 33.7662 | 4 | yes |
| GO:0051247 | positive regulation of protein metabolic process | 33.7662 | 6 | yes |
| GO:0051252 | regulation of RNA metabolic process | 33.7662 | 5 | yes |
| GO:0042981 | regulation of apoptotic process | 33.7662 | 6 | no |
| GO:0043067 | regulation of programmed cell death | 33.7662 | 5 | no |
| GO:0009967 | positive regulation of signal transduction | 32.4675 | 5 | yes |
| GO:0031399 | regulation of protein modification process | 32.4675 | 6 | yes |
| GO:0006355 | regulation of DNA-templated transcription | 31.1688 | 6 | yes |
| GO:1903506 | regulation of nucleic acid-templated transcription | 31.1688 | 7 | yes |
| GO:2001141 | regulation of RNA biosynthetic process | 31.1688 | 6 | yes |
| GO:0010628 | positive regulation of gene expression | 29.8701 | 6 | yes |
| GO:0009892 | negative regulation of metabolic process | 29.8701 | 4 | no |
| GO:0010605 | negative regulation of macromolecule metabolic process | 29.8701 | 5 | no |
| GO:0006996 | organelle organization | 28.5714 | 4 | no |
| GO:0008104 | protein localization | 28.5714 | 4 | no |
| GO:0051172 | negative regulation of nitrogen compound metabolic process | 28.5714 | 5 | no |
| GO:0045935 | positive regulation of nucleobase-containing compound metabolic process | 27.2727 | 6 | yes |
| GO:0071310 | cellular response to organic substance | 27.2727 | 4 | no |
| GO:0051049 | regulation of transport | 27.2727 | 4 | no |
| GO:0019220 | regulation of phosphate metabolic process | 25.9740 | 6 | yes |
| GO:0051174 | regulation of phosphorus metabolic process | 25.9740 | 5 | yes |
| GO:0009891 | positive regulation of biosynthetic process | 24.6753 | 5 | yes |
| GO:0010557 | positive regulation of macromolecule biosynthetic process | 24.6753 | 6 | yes |
| GO:0031328 | positive regulation of cellular biosynthetic process | 24.6753 | 6 | yes |
| GO:0042127 | regulation of cell population proliferation | 24.6753 | 4 | yes |
| GO:0042325 | regulation of phosphorylation | 24.6753 | 7 | yes |
| GO:0045595 | regulation of cell differentiation | 24.6753 | 4 | yes |
| GO:0051240 | positive regulation of multicellular organismal process | 24.6753 | 4 | yes |
| GO:0051254 | positive regulation of RNA metabolic process | 24.6753 | 6 | yes |
| GO:0051248 | negative regulation of protein metabolic process | 24.6753 | 6 | no |
| GO:0071702 | organic substance transport | 23.3766 | 4 | no |
| GO:0043412 | macromolecule modification | 23.3766 | 4 | no |
| GO:0006796 | phosphate-containing compound metabolic process | 23.3766 | 4 | no |
| GO:0031324 | negative regulation of cellular metabolic process | 23.3766 | 5 | no |
| GO:0022607 | cellular component assembly | 23.3766 | 4 | no |
| GO:1902533 | positive regulation of intracellular signal transduction | 23.3766 | 6 | no |
| GO:0031401 | positive regulation of protein modification process | 22.0779 | 7 | yes |
| GO:0051094 | positive regulation of developmental process | 22.0779 | 4 | yes |
| GO:0001932 | regulation of protein phosphorylation | 22.0779 | 7 | no |
| GO:0036211 | protein modification process | 22.0779 | 4 | no |
| GO:0048585 | negative regulation of response to stimulus | 22.0779 | 4 | no |
| GO:0060548 | negative regulation of cell death | 22.0779 | 5 | no |
| GO:0010562 | positive regulation of phosphorus metabolic process | 20.7792 | 6 | yes |
| GO:0042327 | positive regulation of phosphorylation | 20.7792 | 8 | yes |
| GO:0045893 | positive regulation of DNA-templated transcription | 20.7792 | 7 | yes |
| GO:0045937 | positive regulation of phosphate metabolic process | 20.7792 | 7 | yes |
| GO:1902680 | positive regulation of RNA biosynthetic process | 20.7792 | 7 | yes |
| GO:1903508 | positive regulation of nucleic acid-templated transcription | 20.7792 | 8 | yes |
| GO:0032880 | regulation of protein localization | 20.7792 | 5 | no |
| GO:0043066 | negative regulation of apoptotic process | 20.7792 | 7 | no |
| GO:0043069 | negative regulation of programmed cell death | 20.7792 | 6 | no |
| GO:0043085 | positive regulation of catalytic activity | 20.7792 | 4 | no |
| GO:0051050 | positive regulation of transport | 20.7792 | 4 | no |
| GO:0051336 | regulation of hydrolase activity | 20.7792 | 4 | no |
| GO:0060341 | regulation of cellular localization | 20.7792 | 4 | no |
| GO:0071705 | nitrogen compound transport | 20.7792 | 4 | no |
| GO:0043933 | protein-containing complex organization | 20.7792 | 4 | no |
| GO:0001817 | regulation of cytokine production | 19.4805 | 4 | yes |
| GO:2000026 | regulation of multicellular organismal development | 19.4805 | 4 | yes |
| GO:0009894 | regulation of catabolic process | 18.1818 | 4 | yes |
| GO:0006357 | regulation of transcription by RNA polymerase II | 16.8831 | 7 | yes |
| GO:0045597 | positive regulation of cell differentiation | 16.8831 | 5 | yes |
| GO:0001819 | positive regulation of cytokine production | 15.5844 | 5 | yes |
| GO:0008284 | positive regulation of cell population proliferation | 15.5844 | 5 | yes |
| GO:0045944 | positive regulation of transcription by RNA polymerase II | 14.2857 | 8 | yes |
| GO:1903320 | regulation of protein modification by small protein conjugation or removal | 12.9870 | 7 | yes |
| GO:0031329 | regulation of cellular catabolic process | 11.6883 | 5 | yes |
| GO:0050678 | regulation of epithelial cell proliferation | 10.3896 | 5 | yes |
| GO:0009896 | positive regulation of catabolic process | 9.0909 | 5 | yes |
| GO:0050679 | positive regulation of epithelial cell proliferation | 9.0909 | 6 | yes |
| GO:1903706 | regulation of hemopoiesis | 9.0909 | 4 | yes |
| GO:0036293 | response to decreased oxygen levels | 7.7922 | 4 | yes |
| GO:0043620 | regulation of DNA-templated transcription in response to stress | 7.7922 | 4 | yes |
| GO:0045637 | regulation of myeloid cell differentiation | 7.7922 | 5 | yes |
| GO:0090287 | regulation of cellular response to growth factor stimulus | 7.7922 | 4 | yes |
| GO:0031331 | positive regulation of cellular catabolic process | 6.4935 | 6 | yes |
| GO:0043618 | regulation of transcription from RNA polymerase II promoter in response to stress | 6.4935 | 5 | yes |
| GO:0045646 | regulation of erythrocyte differentiation | 6.4935 | 6 | yes |
| GO:0001936 | regulation of endothelial cell proliferation | 5.1948 | 6 | yes |
| GO:0001938 | positive regulation of endothelial cell proliferation | 5.1948 | 7 | yes |
| GO:0006109 | regulation of carbohydrate metabolic process | 5.1948 | 5 | yes |
| GO:0033233 | regulation of protein sumoylation | 5.1948 | 8 | yes |
| GO:0043467 | regulation of generation of precursor metabolites and energy | 5.1948 | 5 | yes |
| GO:0045639 | positive regulation of myeloid cell differentiation | 5.1948 | 6 | yes |
| GO:0045648 | positive regulation of erythrocyte differentiation | 5.1948 | 7 | yes |
| GO:0048568 | embryonic organ development | 5.1948 | 4 | yes |
| GO:0010574 | regulation of vascular endothelial growth factor production | 3.8961 | 5 | yes |
| GO:0010575 | positive regulation of vascular endothelial growth factor production | 3.8961 | 6 | yes |
| GO:0043470 | regulation of carbohydrate catabolic process | 3.8961 | 5 | yes |
| GO:0045913 | positive regulation of carbohydrate metabolic process | 3.8961 | 5 | yes |
| GO:0062012 | regulation of small molecule metabolic process | 3.8961 | 4 | yes |
| GO:0062013 | positive regulation of small molecule metabolic process | 3.8961 | 5 | yes |
| GO:0001892 | embryonic placenta development | 2.5974 | 5 | yes |
| GO:0006110 | regulation of glycolytic process | 2.5974 | 6 | yes |
| GO:0006140 | regulation of nucleotide metabolic process | 2.5974 | 5 | yes |
| GO:0030947 | regulation of vascular endothelial growth factor receptor signaling pathway | 2.5974 | 5 | yes |
| GO:0030949 | positive regulation of vascular endothelial growth factor receptor signaling pathway | 2.5974 | 6 | yes |
| GO:0032350 | regulation of hormone metabolic process | 2.5974 | 4 | yes |
| GO:0032352 | positive regulation of hormone metabolic process | 2.5974 | 5 | yes |
| GO:0033235 | positive regulation of protein sumoylation | 2.5974 | 9 | yes |
| GO:0043619 | regulation of transcription from RNA polymerase II promoter in response to oxidative stress | 2.5974 | 6 | yes |
| GO:0045821 | positive regulation of glycolytic process | 2.5974 | 6 | yes |
| GO:0045981 | positive regulation of nucleotide metabolic process | 2.5974 | 6 | yes |
| GO:0046885 | regulation of hormone biosynthetic process | 2.5974 | 5 | yes |
| GO:0046886 | positive regulation of hormone biosynthetic process | 2.5974 | 6 | yes |
| GO:1900542 | regulation of purine nucleotide metabolic process | 2.5974 | 6 | yes |
| GO:1900544 | positive regulation of purine nucleotide metabolic process | 2.5974 | 7 | yes |
| GO:1903322 | positive regulation of protein modification by small protein conjugation or removal | 2.5974 | 8 | yes |
| GO:1903578 | regulation of ATP metabolic process | 2.5974 | 7 | yes |
| GO:1903580 | positive regulation of ATP metabolic process | 2.5974 | 8 | yes |
Disease
| Term | Name | % | Distance from top the of the tree | Annotated in ARNT_HUMAN |
|---|---|---|---|---|
| DOID:0050686 | organ system cancer | 3.8961 | 3 | no |
| DOID:0050700 | cardiomyopathy | 3.8961 | 4 | no |
| DOID:0060036 | intrinsic cardiomyopathy | 3.8961 | 5 | no |
| DOID:114 | heart disease | 3.8961 | 3 | no |
| DOID:10780 | primary polycythemia | 2.5974 | 5 | no |
| DOID:4961 | bone marrow disease | 2.5974 | 3 | no |
| DOID:8432 | polycythemia | 2.5974 | 4 | no |
| DOID:2843 | long QT syndrome | 2.5974 | 6 | no |
All partners
| Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
|---|---|---|---|---|
| DDB1_HUMAN | [view interactions] | Low throughput | no | yes |
| CUL4A_HUMAN | [view interactions] | Low throughput | no | no |
| CHD4_HUMAN | [view interactions] | Low throughput | no | yes |
| NPAS3_HUMAN | [view interactions] | Low throughput | no | yes |
| NANOG_HUMAN | [view interactions] | Low throughput | no | no |
| SP1_HUMAN | [view interactions] | Low throughput | no | yes |
| TEBP_HUMAN | [view interactions] | Low throughput | no | yes |
| AIP_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| T2FA_HUMAN | [view interactions] | Low throughput | no | yes |
| T2FB_HUMAN | [view interactions] | Low throughput | no | yes |
| PML_HUMAN | [view interactions] | Low throughput | no | yes |
| TBB2A_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| NR0B2_HUMAN | [view interactions] | Low throughput | no | no |
| ESR1_HUMAN | [view interactions] | Low throughput | no | no |
| CASP3_HUMAN | [view interactions] | Low throughput | no | yes |
| CASP9_HUMAN | [view interactions] | Low throughput | no | yes |
| TRIPB_HUMAN | [view interactions] | Low throughput | no | yes |
| VEGFA_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| LAT1_HUMAN | [view interactions] | Low throughput | no | yes |
| CP1B1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| AHR_HUMAN | [view interactions] | Low throughput | no | yes |
| SIM1_HUMAN | [view interactions] | Low throughput | no | no |
| SIM2_HUMAN | [view interactions] | Low throughput | no | yes |
| EPAS1_HUMAN | [view interactions] | Low throughput | no | no |
| CLOCK_HUMAN | [view interactions] | Low throughput | no | yes |
| ARNT_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| HIF1A_HUMAN | [view interactions] | Low throughput | no | no |
| HLF_HUMAN | [view interactions] | Low throughput | no | no |
| DCA15_HUMAN | [view interactions] | Low throughput | no | no |
| NPAS1_HUMAN | [view interactions] | Low throughput | no | no |
| NCOA7_HUMAN | [view interactions] | Low throughput | no | yes |
| NCOR2_HUMAN | [view interactions] | Low throughput | no | yes |
| FOXA2_HUMAN | [view interactions] | Low throughput | no | no |
| NPAS4_HUMAN | [view interactions] | Low throughput | no | yes |
| NCOA2_HUMAN | [view interactions] | Low throughput | no | no |
| NCOA1_HUMAN | [view interactions] | Low throughput | no | yes |
| AHRR_HUMAN | [view interactions] | Low throughput | no | no |
| HEY2_HUMAN | [view interactions] | Low throughput | no | no |
| HEY1_HUMAN | [view interactions] | Low throughput | no | yes |
| HNF4A_HUMAN | [view interactions] | Low throughput | no | no |
| NECD_HUMAN | [view interactions] | Low throughput | no | no |
| CEBPA_HUMAN | [view interactions] | Low throughput | no | yes |
| TRI59_HUMAN | [view interactions] | Low throughput | no | no |
| RB_HUMAN | [view interactions] | Low throughput | no | yes |
| BRCA1_HUMAN | [view interactions] | Low throughput | no | yes |
| CUL2_HUMAN | [view interactions] | Low throughput | no | yes |
| ELOB_HUMAN | [view interactions] | Low throughput | no | no |
| EP300_HUMAN | [view interactions] | Low throughput | no | yes |
| CACO1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| PIAS2_HUMAN | [view interactions] | Low throughput | no | yes |
| JUN_HUMAN | [view interactions] | Low throughput | no | yes |
| HS90A_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| AKT1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| TGM2_HUMAN | [view interactions] | Low throughput | no | no |
| CTNB1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| NEMO_HUMAN | [view interactions] | Low throughput | no | yes |
| HIF3A_HUMAN | [view interactions] | Low throughput | no | yes |
| TACC3_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| SDS3_HUMAN | [view interactions] | Low throughput | no | yes |
| MK04_HUMAN | [view interactions] | Low throughput | no | no |
| PRDX6_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| RAB35_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| TCTP_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| A1AG2_HUMAN | [view interactions] | Low throughput | no | no |
| A1AG1_HUMAN | [view interactions] | Low throughput | no | no |
| MED29_HUMAN | [view interactions] | Low throughput | no | no |
| TCAL6_HUMAN | [view interactions] | Low throughput | no | no |
| TCAL5_HUMAN | [view interactions] | Low throughput | no | no |
| MP2K3_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| GIP_HUMAN | [view interactions] | High throughput | no | no |
| HSP72_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| SBP1_HUMAN | [view interactions] | High throughput | no | no |
| LYOX_HUMAN | [view interactions] | High throughput | no | no |
| CALL3_HUMAN | [view interactions] | High throughput | no | yes |
| TNNC2_HUMAN | [view interactions] | High throughput | no | no |
| NDOR1_HUMAN | [view interactions] | High throughput | no | yes |
| MD2L1_HUMAN | [view interactions] | High throughput | no | no |
| BAG2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| BOP_HUMAN | [view interactions] | High throughput | no | no |
| ZSC18_HUMAN | [view interactions] | High throughput | no | yes |
| FEM1A_HUMAN | [view interactions] | High throughput | no | no |
| TIM8A_HUMAN | [view interactions] | High throughput | no | yes |
| SHRPN_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PCCB_HUMAN | [view interactions] | High throughput | no | yes |
| PLAK_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FAS_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| TP4A3_HUMAN | [view interactions] | High throughput | no | no |
| EGFR_HUMAN | [view interactions] | High throughput | no | no |
| IMA5_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| IMA4_HUMAN | [view interactions] | High throughput | no | yes |
| IMA6_HUMAN | [view interactions] | High throughput | no | yes |
| IMA7_HUMAN | [view interactions] | High throughput | no | yes |
| CCND2_HUMAN | [view interactions] | High throughput | no | yes |
| CCNE1_HUMAN | [view interactions] | High throughput | no | no |
| CDK4_HUMAN | [view interactions] | High throughput | no | no |
| CDK6_HUMAN | [view interactions] | High throughput | no | yes |
| CDN2B_HUMAN | [view interactions] | High throughput | no | no |
| EPHA2_HUMAN | [view interactions] | High throughput | no | no |
| FGFR4_HUMAN | [view interactions] | High throughput | no | no |
| STK11_HUMAN | [view interactions] | High throughput | no | yes |
| FZR1_HUMAN | [view interactions] | High throughput | no | no |
| MYC_HUMAN | [view interactions] | High throughput | no | yes |
| MERL_HUMAN | [view interactions] | High throughput | no | yes |
| CD44_HUMAN | [view interactions] | High throughput | no | yes |
| CDN2C_HUMAN | [view interactions] | High throughput | no | yes |
| ERBB2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| LATS2_HUMAN | [view interactions] | High throughput | no | yes |
| TEAD2_HUMAN | [view interactions] | High throughput | no | no |
| BECN1_HUMAN | [view interactions] | High throughput | no | yes |
| GLIS1_HUMAN | [view interactions] | High throughput | no | no |
| GLIS2_HUMAN | [view interactions] | High throughput | no | no |
| HGF_HUMAN | [view interactions] | High throughput | no | yes |
| MP2K5_HUMAN | [view interactions] | High throughput | no | yes |
| MK14_HUMAN | [view interactions] | High throughput | no | yes |
| PGFRA_HUMAN | [view interactions] | High throughput | no | no |
| RAF1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| TF65_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| P53_HUMAN | [view interactions] | High throughput | no | no |
| PDK1_HUMAN | [view interactions] | High throughput | no | yes |
| F263_HUMAN | [view interactions] | High throughput | no | yes |
| F264_HUMAN | [view interactions] | High throughput | no | no |
| LDHA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HXK1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PFKAM_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ICAM1_HUMAN | [view interactions] | High throughput | no | no |
| ABT1_HUMAN | [view interactions] | High throughput | no | no |
| ARI5A_HUMAN | [view interactions] | High throughput | no | yes |
| FOS_HUMAN | [view interactions] | High throughput | no | yes |
| LDB2_HUMAN | [view interactions] | High throughput | no | yes |
| TEAD1_HUMAN | [view interactions] | High throughput | no | no |
| YAP1_HUMAN | [view interactions] | High throughput | no | yes |
| ARNT2_HUMAN | [view interactions] | High throughput | no | yes |
| DEAF1_HUMAN | [view interactions] | High throughput | no | yes |
| NR4A3_HUMAN | [view interactions] | High throughput | no | yes |
| NR6A1_HUMAN | [view interactions] | High throughput | no | no |
| RBL2_HUMAN | [view interactions] | High throughput | no | yes |
| SENP6_HUMAN | [view interactions] | High throughput | no | yes |
| SIN3A_HUMAN | [view interactions] | High throughput | no | yes |
| HTF4_HUMAN | [view interactions] | High throughput | no | yes |
| TF7L2_HUMAN | [view interactions] | High throughput | no | yes |
| AP2D_HUMAN | [view interactions] | High throughput | no | no |
| TFEB_HUMAN | [view interactions] | High throughput | no | no |
| WWTR1_HUMAN | [view interactions] | High throughput | no | yes |
| ZEB1_HUMAN | [view interactions] | High throughput | no | yes |
| SMG7_HUMAN | [view interactions] | High throughput | no | no |
| ASF1A_HUMAN | [view interactions] | High throughput | no | no |
| TE2IP_HUMAN | [view interactions] | High throughput | no | yes |
| SMAD9_HUMAN | [view interactions] | High throughput | no | yes |
| BACD2_HUMAN | [view interactions] | High throughput | no | no |
| LSM8_HUMAN | [view interactions] | High throughput | no | yes |
| HIF1N_HUMAN | [view interactions] | High throughput | no | yes |
| EGLN3_HUMAN | [view interactions] | High throughput | no | no |
| BCAT1_HUMAN | [view interactions] | High throughput | no | no |
| FOXR2_HUMAN | [view interactions] | High throughput | no | no |
| C1QT2_HUMAN | [view interactions] | High throughput | no | yes |
| CIAO3_HUMAN | [view interactions] | High throughput | no | yes |
| SLX1_HUMAN | [view interactions] | High throughput | no | yes |
| HSP7C_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ERR1_HUMAN | [view interactions] | High throughput | no | yes |
| ERR2_HUMAN | [view interactions] | High throughput | no | no |
| ERR3_HUMAN | [view interactions] | High throughput | no | yes |
| KCNH2_HUMAN | [view interactions] | High throughput | no | no |
| ADHX_HUMAN | [view interactions] | High throughput | no | yes |
| GEMI_HUMAN | [view interactions] | High throughput | no | no |
| IRAK4_HUMAN | [view interactions] | High throughput | no | yes |
| STRBP_HUMAN | [view interactions] | High throughput | no | yes |
| DBLOH_HUMAN | [view interactions] | High throughput | no | no |
| MTA3_HUMAN | [view interactions] | High throughput | no | yes |
| CREB1_HUMAN | [view interactions] | High throughput | no | yes |
| FOXN1_HUMAN | [view interactions] | High throughput | no | no |
| FEV_HUMAN | [view interactions] | High throughput | no | no |
| PAX7_HUMAN | [view interactions] | High throughput | no | no |
| SOX2_HUMAN | [view interactions] | High throughput | no | yes |
| SOX6_HUMAN | [view interactions] | High throughput | no | yes |
| SP7_HUMAN | [view interactions] | High throughput | no | no |
| ARL14_HUMAN | [view interactions] | High throughput | no | no |
| ELAV1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HERC2_HUMAN | [view interactions] | High throughput | no | yes |
| OSTM1_HUMAN | [view interactions] | High throughput | no | yes |
| GLYC_HUMAN | [view interactions] | High throughput | no | no |
| MYH10_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SPTB2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MYH9_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| SRC8_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CALM2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CALM3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CALM1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RAC1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| MYO1B_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| KLC1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| HSPB1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RL4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| 2AAA_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| GNAI2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RASK_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| 1433S_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PAXI_HUMAN | [view interactions] | High throughput | no | yes |
| DYN2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MYL6_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| HDAC1_HUMAN | [view interactions] | High throughput | no | no |
| CAND1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ARPC2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SMCA5_HUMAN | [view interactions] | High throughput | no | yes |
| LRC59_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GNAI1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RUVB2_HUMAN | [view interactions] | High throughput | no | yes |
| IPYR_HUMAN | [view interactions] | High throughput | no | yes |
| RL35A_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| FYN_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| TIF1B_HUMAN | [view interactions] | High throughput | no | yes |
| RTN4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NONO_HUMAN | [view interactions] | High throughput | no | yes |
| LAP2A_HUMAN | [view interactions] | High throughput | no | yes |
| SGT1_HUMAN | [view interactions] | High throughput | no | no |
| TENS3_HUMAN | [view interactions] | High throughput | no | no |
| XRCC6_HUMAN | [view interactions] | High throughput | no | yes |
| PUR8_HUMAN | [view interactions] | High throughput | no | yes |
| RL7_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RL19_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PP1A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PSMD2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CDK9_HUMAN | [view interactions] | High throughput | no | yes |
| H13_HUMAN | [view interactions] | High throughput | no | no |
| RUVB1_HUMAN | [view interactions] | High throughput | no | yes |
| RL27_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HS71B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HS71A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SYT7_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FLOT2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RS5_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LYN_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RL18_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DNJA2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| M2OM_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RANG_HUMAN | [view interactions] | High throughput | no | no |
| MYO1C_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CH60_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MATR3_HUMAN | [view interactions] | High throughput | no | yes |
| SI1L3_HUMAN | [view interactions] | High throughput | no | yes |
| DPM1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CNBP_HUMAN | [view interactions] | High throughput | no | no |
| MPRIP_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PYR1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HMGB1_HUMAN | [view interactions] | High throughput | no | yes |
| ESR2_HUMAN | [view interactions] | High throughput | no | no |
| H4_HUMAN | [view interactions] | High throughput | no | yes |
| EGLN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CIC_HUMAN | [view interactions] | High throughput | no | yes |
| VHL_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ELOC_HUMAN | [view interactions] | High throughput | no | no |
| OR6K3_HUMAN | [view interactions] | High throughput | no | no |
| S10A8_HUMAN | [view interactions] | High throughput | no | no |
| S10A9_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| NOS3_HUMAN | [view interactions] | Computational | no | no |
| CAH9_HUMAN | [view interactions] | Computational | no | no |
| HIG1A_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| SIR1_HUMAN | [view interactions] | Computational | no | yes |
| CSN5_HUMAN | [view interactions] | Computational | no | yes |
| EGLN2_HUMAN | [view interactions] | Computational | no | no |
| CP1A1_HUMAN | [view interactions] | Computational | no | yes |
| CBP_HUMAN | [view interactions] | Computational | no | yes |
| CDN1A_HUMAN | [view interactions] | Computational | no | no |
| SMAD3_HUMAN | [view interactions] | Computational | no | yes |
| HDAC7_HUMAN | [view interactions] | Computational | no | no |
| ASPH_HUMAN | [view interactions] | Computational | no | yes |
| IF2P_HUMAN | [view interactions] | Computational | no | yes |
| SMAD4_HUMAN | [view interactions] | Computational | no | yes |
| APEX1_HUMAN | [view interactions] | Computational | no | yes |
| EPO_HUMAN | [view interactions] | Computational | no | no |
| EDN1_HUMAN | [view interactions] | Computational | no | no |