Features Interactions Isoform Disease Linear motifs Fingerprint Network All partners

KLC1_HUMAN

GO
G2C
SynGO

Kinesin is a microtubule-associated force-producing protein that may play a role in organelle transport. The light chain may function in coupling of cargo to the heavy chain or in the modulation of its ATPase activity. [View more on UniProt]

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Download full PS network for entry.

No data found.

No annotated instance was found. To search for linear motifs, use the ELM prediction server.

Molecular function

Term Name % Distance from the top of the tree Annotated in KLC1_HUMAN
GO:0043168 anion binding 35.4167 4 no
GO:0000166 nucleotide binding 34.3750 4 no
GO:0017076 purine nucleotide binding 34.3750 5 no
GO:0032555 purine ribonucleotide binding 34.3750 4 no
GO:0035639 purine ribonucleoside triphosphate binding 34.3750 4 no
GO:0005524 ATP binding 30.2083 5 no
GO:0030554 adenyl nucleotide binding 30.2083 6 no
GO:0032559 adenyl ribonucleotide binding 30.2083 5 no
GO:0003723 RNA binding 27.0833 4 no
GO:0045296 cadherin binding 23.9583 4 no
GO:0019894 kinesin binding 9.3750 4 yes

Biological process

Term Name % Distance from top the of the tree Annotated in KLC1_HUMAN
GO:0048522 positive regulation of cellular process 59.3750 4 no
GO:0060255 regulation of macromolecule metabolic process 56.2500 4 no
GO:0080090 regulation of primary metabolic process 54.1667 4 no
GO:0031323 regulation of cellular metabolic process 53.1250 4 no
GO:0048523 negative regulation of cellular process 50.0000 4 no
GO:0051128 regulation of cellular component organization 47.9167 4 no
GO:0009889 regulation of biosynthetic process 45.8333 4 no
GO:0010556 regulation of macromolecule biosynthetic process 45.8333 5 no
GO:0031326 regulation of cellular biosynthetic process 45.8333 5 no
GO:0051246 regulation of protein metabolic process 43.7500 5 no
GO:0010646 regulation of cell communication 43.7500 4 no
GO:0010468 regulation of gene expression 41.6667 6 no
GO:0009966 regulation of signal transduction 38.5417 4 no
GO:0009893 positive regulation of metabolic process 38.5417 4 no
GO:0006996 organelle organization 36.4583 4 yes
GO:0008104 protein localization 36.4583 4 no
GO:0010604 positive regulation of macromolecule metabolic process 36.4583 5 no
GO:0031325 positive regulation of cellular metabolic process 34.3750 5 no
GO:0009892 negative regulation of metabolic process 33.3333 4 no
GO:0031399 regulation of protein modification process 33.3333 6 no
GO:0010605 negative regulation of macromolecule metabolic process 32.2917 5 no
GO:0048584 positive regulation of response to stimulus 32.2917 4 no
GO:0010647 positive regulation of cell communication 32.2917 5 no
GO:0023056 positive regulation of signaling 32.2917 4 no
GO:0031324 negative regulation of cellular metabolic process 31.2500 5 no
GO:0019219 regulation of nucleobase-containing compound metabolic process 31.2500 5 no
GO:0019220 regulation of phosphate metabolic process 28.1250 6 no
GO:0051049 regulation of transport 28.1250 4 no
GO:0051174 regulation of phosphorus metabolic process 28.1250 5 no
GO:0071702 organic substance transport 28.1250 4 no
GO:0051130 positive regulation of cellular component organization 28.1250 5 no
GO:1902531 regulation of intracellular signal transduction 28.1250 5 no
GO:0009891 positive regulation of biosynthetic process 28.1250 5 no
GO:0031328 positive regulation of cellular biosynthetic process 28.1250 6 no
GO:0051252 regulation of RNA metabolic process 28.1250 5 no
GO:0071705 nitrogen compound transport 27.0833 4 no
GO:0009894 regulation of catabolic process 27.0833 4 no
GO:0022607 cellular component assembly 27.0833 4 no
GO:0010557 positive regulation of macromolecule biosynthetic process 27.0833 6 no
GO:0060341 regulation of cellular localization 26.0417 4 no
GO:0051247 positive regulation of protein metabolic process 26.0417 6 no
GO:0044087 regulation of cellular component biogenesis 26.0417 4 no
GO:0033043 regulation of organelle organization 25.0000 5 no
GO:0006355 regulation of DNA-templated transcription 25.0000 7 no
GO:2001141 regulation of RNA biosynthetic process 25.0000 6 no
GO:0042325 regulation of phosphorylation 23.9583 7 no
GO:0009967 positive regulation of signal transduction 23.9583 5 no
GO:0043067 regulation of programmed cell death 23.9583 4 no
GO:0043933 protein-containing complex organization 22.9167 4 yes
GO:0001932 regulation of protein phosphorylation 22.9167 7 no
GO:0015031 protein transport 22.9167 4 no
GO:0032880 regulation of protein localization 22.9167 5 no
GO:0036211 protein modification process 22.9167 4 no
GO:0043412 macromolecule modification 22.9167 4 no
GO:0042981 regulation of apoptotic process 22.9167 5 no
GO:0080134 regulation of response to stress 21.8750 4 no
GO:0009890 negative regulation of biosynthetic process 21.8750 5 no
GO:0010558 negative regulation of macromolecule biosynthetic process 21.8750 6 no
GO:0031327 negative regulation of cellular biosynthetic process 21.8750 6 no
GO:0006796 phosphate-containing compound metabolic process 20.8333 4 no
GO:0030030 cell projection organization 20.8333 4 no
GO:0048585 negative regulation of response to stimulus 20.8333 4 no
GO:0007010 cytoskeleton organization 20.8333 5 no
GO:0071310 cellular response to organic substance 20.8333 4 no
GO:0022411 cellular component disassembly 8.3333 4 yes
GO:0032984 protein-containing complex disassembly 6.2500 5 yes
GO:1903008 organelle disassembly 4.1667 5 yes
GO:0032988 protein-RNA complex disassembly 2.0833 6 yes
GO:0035617 stress granule disassembly 2.0833 6 yes
GO:0071826 protein-RNA complex organization 2.0833 5 yes

Disease

No data found.

Uniprot ID Details Highest evidence Localizing into PSD HPA (protein expression in neurons)
S10A6_HUMAN [view interactions] Low throughput no yes
SYNE4_HUMAN [view interactions] Low throughput no yes
KINH_HUMAN [view entry] [view interactions] Low throughput yes no
KLC2_HUMAN [view entry] [view interactions] Low throughput yes yes
JIP3_HUMAN [view entry] [view interactions] Low throughput yes yes
JIP4_HUMAN [view interactions] Low throughput no yes
FAT1_HUMAN [view interactions] Low throughput no yes
ARH_HUMAN [view interactions] Low throughput no yes
RASF8_HUMAN [view interactions] Low throughput no yes
AAKG3_HUMAN [view interactions] Low throughput no no
BSDC1_HUMAN [view interactions] Low throughput no no
RIC3_HUMAN [view interactions] Low throughput no yes
RUSC1_HUMAN [view entry] [view interactions] Low throughput yes yes
HAP1_HUMAN [view entry] [view interactions] Low throughput yes yes
MK08_HUMAN [view interactions] Low throughput no yes
HSP7C_HUMAN [view entry] [view interactions] Low throughput yes yes
KCRB_HUMAN [view entry] [view interactions] Low throughput yes no
KIF5C_HUMAN [view entry] [view interactions] Low throughput yes yes
KIF5A_HUMAN [view entry] [view interactions] Low throughput yes yes
SYUA_HUMAN [view entry] [view interactions] Low throughput yes no
TAU_HUMAN [view entry] [view interactions] Low throughput yes yes
SKP1_HUMAN [view interactions] Low throughput no yes
MINY2_HUMAN [view interactions] Low throughput no no
A4_HUMAN [view entry] [view interactions] Low throughput yes yes
CSTN1_HUMAN [view entry] [view interactions] Low throughput yes yes
JIP1_HUMAN [view entry] [view interactions] Low throughput yes yes
RAB10_HUMAN [view entry] [view interactions] Low throughput yes yes
RUSC2_HUMAN [view interactions] Low throughput no yes
BAP1_HUMAN [view interactions] High throughput no yes
PARPT_HUMAN [view interactions] High throughput no no
TRI67_HUMAN [view interactions] High throughput no no
RPN2_HUMAN [view entry] [view interactions] High throughput yes yes
EPHA2_HUMAN [view interactions] High throughput no no
EPHB2_HUMAN [view entry] [view interactions] High throughput yes yes
EPHB4_HUMAN [view interactions] High throughput no yes
COPD_HUMAN [view entry] [view interactions] High throughput yes yes
COPB_HUMAN [view interactions] High throughput no yes
COPZ1_HUMAN [view interactions] High throughput no no
DIAP1_HUMAN [view interactions] High throughput no yes
TLE3_HUMAN [view interactions] High throughput no yes
PTN23_HUMAN [view entry] [view interactions] High throughput yes yes
P4R3B_HUMAN [view interactions] High throughput no yes
PSD11_HUMAN [view entry] [view interactions] High throughput yes yes
PSD12_HUMAN [view interactions] High throughput no yes
IPO5_HUMAN [view entry] [view interactions] High throughput yes yes
HAT1_HUMAN [view interactions] High throughput no yes
DC1L2_HUMAN [view entry] [view interactions] High throughput yes yes
PSMD3_HUMAN [view interactions] High throughput no yes
PPIH_HUMAN [view interactions] High throughput no yes
OGA_HUMAN [view interactions] High throughput no yes
CSDE1_HUMAN [view interactions] High throughput no yes
PSD10_HUMAN [view entry] [view interactions] High throughput yes yes
TRI16_HUMAN [view interactions] High throughput no no
HS71B_HUMAN [view entry] [view interactions] High throughput yes yes
HS71A_HUMAN [view entry] [view interactions] High throughput yes yes
RO60_HUMAN [view interactions] High throughput no yes
BIP_HUMAN [view entry] [view interactions] High throughput yes yes
PABP1_HUMAN [view entry] [view interactions] High throughput yes yes
IMDH2_HUMAN [view interactions] High throughput no yes
RINI_HUMAN [view interactions] High throughput no yes
ERF3A_HUMAN [view interactions] High throughput no yes
GNS_HUMAN [view interactions] High throughput no yes
PYRG1_HUMAN [view interactions] High throughput no no
PRS6A_HUMAN [view entry] [view interactions] High throughput yes yes
PTN1_HUMAN [view entry] [view interactions] High throughput yes yes
ML12A_HUMAN [view interactions] High throughput no no
NFKB1_HUMAN [view interactions] High throughput no yes
IF4B_HUMAN [view entry] [view interactions] High throughput yes yes
PSA1_HUMAN [view interactions] High throughput no yes
MAP4_HUMAN [view entry] [view interactions] High throughput yes no
PSA5_HUMAN [view interactions] High throughput no yes
2AAA_HUMAN [view entry] [view interactions] High throughput yes no
MYH9_HUMAN [view entry] [view interactions] High throughput yes no
PRS7_HUMAN [view interactions] High throughput no yes
RBMX_HUMAN [view entry] [view interactions] High throughput yes yes
NAA10_HUMAN [view interactions] High throughput no yes
KPCI_HUMAN [view entry] [view interactions] High throughput yes yes
LPPRC_HUMAN [view entry] [view interactions] High throughput yes yes
PRS6B_HUMAN [view interactions] High throughput no yes
RS10_HUMAN [view entry] [view interactions] High throughput yes yes
IQGA1_HUMAN [view entry] [view interactions] High throughput yes no
CAPZB_HUMAN [view entry] [view interactions] High throughput yes yes
FAS_HUMAN [view entry] [view interactions] High throughput yes no
F10A1_HUMAN [view interactions] High throughput no yes
TCPQ_HUMAN [view entry] [view interactions] High throughput yes yes
PSMD7_HUMAN [view interactions] High throughput no yes
HNRPF_HUMAN [view interactions] High throughput no yes
SPSY_HUMAN [view interactions] High throughput no no
CAZA1_HUMAN [view entry] [view interactions] High throughput yes yes
SNAA_HUMAN [view entry] [view interactions] High throughput yes yes
PSMD4_HUMAN [view interactions] High throughput no yes
GFRA1_HUMAN [view interactions] High throughput no no
ACTB_HUMAN [view entry] [view interactions] High throughput yes no
RS20_HUMAN [view entry] [view interactions] High throughput yes yes
HNRPK_HUMAN [view entry] [view interactions] High throughput yes yes
PP1A_HUMAN [view entry] [view interactions] High throughput yes yes
PP1B_HUMAN [view entry] [view interactions] High throughput yes yes
PRS4_HUMAN [view entry] [view interactions] High throughput yes yes
PRS8_HUMAN [view interactions] High throughput no yes
PRS10_HUMAN [view interactions] High throughput no yes
PP2AB_HUMAN [view interactions] High throughput no yes
2ABA_HUMAN [view interactions] High throughput no yes
SRSF3_HUMAN [view interactions] High throughput no yes
IF4G1_HUMAN [view entry] [view interactions] High throughput yes yes
NCBP1_HUMAN [view interactions] High throughput no yes
ACACA_HUMAN [view entry] [view interactions] High throughput yes yes
PSMD2_HUMAN [view entry] [view interactions] High throughput yes yes
DC1I2_HUMAN [view entry] [view interactions] High throughput yes yes
GOGA4_HUMAN [view interactions] High throughput no yes
ASAH1_HUMAN [view interactions] High throughput no yes
DYHC1_HUMAN [view entry] [view interactions] High throughput yes yes
NUMA1_HUMAN [view interactions] High throughput no yes
PSMD6_HUMAN [view interactions] High throughput no yes
ELOB_HUMAN [view interactions] High throughput no no
TSN_HUMAN [view interactions] High throughput no yes
ADRM1_HUMAN [view interactions] High throughput no yes
DDB1_HUMAN [view interactions] High throughput no yes
VP26B_HUMAN [view entry] [view interactions] High throughput yes yes
HEAT6_HUMAN [view interactions] High throughput no no
LARP1_HUMAN [view interactions] High throughput no yes
5MP2_HUMAN [view interactions] High throughput no yes
CARM1_HUMAN [view interactions] High throughput no yes
GEMI5_HUMAN [view interactions] High throughput no yes
HS105_HUMAN [view entry] [view interactions] High throughput yes yes
RAD50_HUMAN [view interactions] High throughput no yes
OTUB1_HUMAN [view interactions] High throughput no yes
PDLI5_HUMAN [view entry] [view interactions] High throughput yes no
TOPK_HUMAN [view interactions] High throughput no no
PSB7_HUMAN [view interactions] High throughput no yes
PSMD1_HUMAN [view entry] [view interactions] High throughput yes yes
TSNAX_HUMAN [view interactions] High throughput no yes
TCPH_HUMAN [view entry] [view interactions] High throughput yes yes
MCMBP_HUMAN [view interactions] High throughput no yes
PAR6B_HUMAN [view interactions] High throughput no no
CE295_HUMAN [view interactions] High throughput no yes
SLK_HUMAN [view entry] [view interactions] High throughput yes yes
RPAP3_HUMAN [view interactions] High throughput no yes
DDX21_HUMAN [view interactions] High throughput no yes
RBX2_HUMAN [view interactions] High throughput no yes
DJB11_HUMAN [view interactions] High throughput no yes
NRBP_HUMAN [view interactions] High throughput no yes
PSD13_HUMAN [view interactions] High throughput no yes
TRI33_HUMAN [view interactions] High throughput no yes
RUVB2_HUMAN [view interactions] High throughput no yes
RBGP1_HUMAN [view interactions] High throughput no yes
PRC2C_HUMAN [view interactions] High throughput no yes
UCHL5_HUMAN [view interactions] High throughput no yes
DC1L1_HUMAN [view entry] [view interactions] High throughput yes yes
S23IP_HUMAN [view interactions] High throughput no yes
GBF1_HUMAN [view interactions] High throughput no yes
RFFL_HUMAN [view interactions] High throughput no yes
HOOK1_HUMAN [view interactions] High throughput no no
ANC2_HUMAN [view interactions] High throughput no no
NAA40_HUMAN [view interactions] High throughput no no
CCNF_HUMAN [view interactions] High throughput no no
KDM1A_HUMAN [view interactions] High throughput no yes
HDAC1_HUMAN [view interactions] High throughput no no
PF21A_HUMAN [view interactions] High throughput no yes
MK06_HUMAN [view interactions] High throughput no yes
RCOR1_HUMAN [view interactions] High throughput no yes
RAB18_HUMAN [view entry] [view interactions] High throughput yes yes
GLUT4_HUMAN [view interactions] High throughput no no
RFA1_HUMAN [view interactions] High throughput no yes
RIPK4_HUMAN [view interactions] High throughput no no
RFA2_HUMAN [view interactions] High throughput no yes
RFA3_HUMAN [view interactions] High throughput no yes
KLC4_HUMAN [view interactions] High throughput no yes
WWTR1_HUMAN [view interactions] High throughput no yes
AVL9_HUMAN [view interactions] High throughput no yes
SYNPO_HUMAN [view entry] [view interactions] High throughput yes no
RFIP2_HUMAN [view entry] [view interactions] High throughput yes yes
RFIP1_HUMAN [view interactions] High throughput no yes
ZN503_HUMAN [view interactions] High throughput no yes
PIAS1_HUMAN [view entry] [view interactions] High throughput yes yes
RPB3_HUMAN [view interactions] High throughput no yes
CLK1_HUMAN [view interactions] High throughput no yes
CEP44_HUMAN [view interactions] High throughput no yes
DPY30_HUMAN [view interactions] High throughput no yes
OFD1_HUMAN [view interactions] High throughput no yes
1433T_HUMAN [view entry] [view interactions] High throughput yes yes
1433G_HUMAN [view entry] [view interactions] High throughput yes yes
1433F_HUMAN [view entry] [view interactions] High throughput yes yes
1433Z_HUMAN [view entry] [view interactions] High throughput yes yes
1433B_HUMAN [view entry] [view interactions] High throughput yes yes
1433E_HUMAN [view entry] [view interactions] High throughput yes yes
CUL9_HUMAN [view interactions] High throughput no no
ICOS_HUMAN [view interactions] High throughput no no
FMR1_HUMAN [view entry] [view interactions] High throughput yes yes
ITM2B_HUMAN [view interactions] High throughput no yes
TLK2_HUMAN [view interactions] High throughput no no
CP135_HUMAN [view interactions] High throughput no no
CEP63_HUMAN [view interactions] High throughput no yes
BNIP2_HUMAN [view interactions] High throughput no yes
K1H1_HUMAN [view interactions] High throughput no no
ODAD1_HUMAN [view interactions] High throughput no no
LRSM1_HUMAN [view entry] [view interactions] High throughput yes yes
TSC1_HUMAN [view entry] [view interactions] High throughput yes yes
ADRB2_HUMAN [view entry] [view interactions] High throughput yes no
PAR2_HUMAN [view entry] [view interactions] High throughput yes yes
PE2R4_HUMAN [view interactions] High throughput no yes
ERBB2_HUMAN [view entry] [view interactions] High throughput yes no
1433S_HUMAN [view entry] [view interactions] High throughput yes yes
DISC1_HUMAN [view entry] [view interactions] High throughput yes no
HSPB1_HUMAN [view entry] [view interactions] High throughput yes no
CEP43_HUMAN [view interactions] High throughput no no
LMTK2_HUMAN [view entry] [view interactions] High throughput yes yes
FHI1A_HUMAN [view interactions] High throughput no yes
FHI2A_HUMAN [view interactions] High throughput no yes
FHI2B_HUMAN [view interactions] High throughput no yes
HOOK2_HUMAN [view interactions] High throughput no yes
CFTR_HUMAN [view interactions] High throughput no no
CBY1_HUMAN [view interactions] High throughput no no
NIN_HUMAN [view interactions] High throughput no no
PCM1_HUMAN [view interactions] High throughput no yes
TACC3_HUMAN [view entry] [view interactions] High throughput yes yes
AP1AR_HUMAN [view interactions] High throughput no yes
ATCAY_HUMAN [view interactions] High throughput no no
EZH2_HUMAN [view interactions] High throughput no no
TRAK2_HUMAN [view interactions] High throughput no yes
DTBP1_HUMAN [view entry] [view interactions] High throughput yes yes
KPTN_HUMAN [view entry] [view interactions] High throughput yes yes
AZIN1_HUMAN [view interactions] High throughput no yes
TRIP6_HUMAN [view interactions] High throughput no yes
UBP7_HUMAN [view interactions] High throughput no yes
NTRK1_HUMAN [view interactions] High throughput no yes
KC1D_HUMAN [view entry] [view interactions] High throughput yes yes
RAP1B_HUMAN [view entry] [view interactions] High throughput yes no
SORT_HUMAN [view interactions] High throughput no yes
KLC3_HUMAN [view interactions] High throughput no no
NOLC1_HUMAN [view interactions] High throughput no yes
ORC3_HUMAN [view interactions] High throughput no yes
RFOX1_HUMAN [view interactions] High throughput no yes
COG6_HUMAN [view interactions] High throughput no yes
KIF2B_HUMAN [view entry] [view interactions] High throughput yes yes
MYCL_HUMAN [view interactions] High throughput no no
RHG17_HUMAN [view interactions] High throughput no no
SNAPN_HUMAN [view interactions] High throughput no yes
EXOC3_HUMAN [view entry] [view interactions] High throughput yes no
TP4AP_HUMAN [view interactions] High throughput no yes
RABE2_HUMAN [view interactions] High throughput no yes
USF1_HUMAN [view interactions] High throughput no yes
CCD83_HUMAN [view interactions] High throughput no no
TRI25_HUMAN [view interactions] High throughput no yes
ZN598_HUMAN [view interactions] High throughput no no
ARNT_HUMAN [view entry] [view interactions] High throughput yes yes
RASK_HUMAN [view entry] [view interactions] High throughput yes no
UBC12_HUMAN [view entry] [view interactions] High throughput yes yes
VIR_HUMAN [view interactions] High throughput no yes
APEX1_HUMAN [view interactions] High throughput no yes
TIF1B_HUMAN [view interactions] High throughput no yes
MLP3B_HUMAN [view interactions] High throughput no yes
MK01_HUMAN [view entry] [view interactions] High throughput yes yes
DJC16_HUMAN [view interactions] High throughput no no
DJC18_HUMAN [view interactions] High throughput no yes
RIGI_HUMAN [view interactions] High throughput no yes
PRPS2_HUMAN [view interactions] High throughput no no
S10A2_HUMAN [view interactions] High throughput no no
SPSB4_HUMAN [view interactions] High throughput no no
PSA_HUMAN [view entry] [view interactions] High throughput yes yes
EP300_HUMAN [view interactions] High throughput no yes
PRKN_HUMAN [view entry] [view interactions] High throughput yes yes
CUL3_HUMAN [view entry] [view interactions] High throughput yes yes
ZRAN1_HUMAN [view interactions] High throughput no yes