HAP1_HUMAN
Evidence for PS localization
Functions
Originally identified as neuronal protein that specifically associates with HTT/huntingtin and the binding is enhanced by an expanded polyglutamine repeat within HTT possibly affecting HAP1 interaction properties. Both HTT and HAP1 are involved in intracellular trafficking and HAP1 is proposed to link HTT to motor proteins and/or transport cargos. Seems to play a role in vesicular transport within neurons and axons such as from early endosomes to late endocytic compartments and to promote neurite outgrowth. The vesicular transport function via association with microtubule-dependent transporters can be attenuated by association with mutant HTT. Involved in the axonal transport of BDNF and its activity-dependent secretion; the function seems to involve HTT, DCTN1 and a complex with SORT1. Involved in APP trafficking and seems to facilitate APP anterograde transport and membrane insertion thereby possibly reducing processing into amyloid beta. Involved in delivery of gamma-aminobutyric acid (GABA(A)) receptors to synapses; the function is dependent on kinesin motor protein KIF5 and is disrupted by HTT with expanded polyglutamine repeat. Involved in regulation of autophagosome motility by promoting efficient retrograde axonal transport. Seems to be involved in regulation of membrane receptor recycling and degradation, and respective signal transduction, including GABA(A) receptors, tyrosine kinase receptors, EGFR, IP3 receptor and androgen receptor. Among others suggested to be involved in control of feeding behavior (involving hypothalamic GABA(A) receptors), cerebellar and brainstem development (involving AHI1 and NTRK1/TrkA), postnatal neurogenesis (involving hypothalamic NTRK2/TrkB), and ITPR1/InsP3R1-mediated Ca(2+) release (involving HTT and possibly the effect of mutant HTT). Via association with DCTN1/dynactin p150-glued and HTT/huntingtin involved in cytoplasmic retention of REST in neurons. May be involved in ciliogenesis. Involved in regulation of exocytosis. Seems to be involved in formation of cytoplasmic inclusion bodies (STBs). In case of anomalous expression of TBP, can sequester a subset of TBP into STBs; sequestration is enhanced by an expanded polyglutamine repeat within TBP. HAP1-containing STBs have been proposed to play a protective role against neurodegeneration in Huntigton disease (HD) and spinocerebellar ataxia 17 (SCA17). [View more on UniProt]
Protein features
Binary interactions with known binding regions
To display all evidence describing the interaction with a partner, click on the protein name left to the bars.
Network
Isoforms
Disease-causing germline mutations
No data found.
Linear motifs
No annotated instance was found. To search for linear motifs, use the ELM prediction server.
Fingerprint
Molecular function
| Term | Name | % | Distance from the top of the tree | Annotated in HAP1_HUMAN |
|---|---|---|---|---|
| GO:0017076 | purine nucleotide binding | 26.9841 | 4 | no |
| GO:0032555 | purine ribonucleotide binding | 26.9841 | 4 | no |
| GO:0035639 | purine ribonucleoside triphosphate binding | 26.9841 | 4 | no |
| GO:0005524 | ATP binding | 25.3968 | 5 | no |
| GO:0030554 | adenyl nucleotide binding | 25.3968 | 5 | no |
| GO:0032559 | adenyl ribonucleotide binding | 25.3968 | 5 | no |
| GO:0003723 | RNA binding | 23.8095 | 4 | no |
| GO:0015631 | tubulin binding | 20.6349 | 4 | no |
| GO:0017022 | myosin binding | 3.1746 | 4 | yes |
| GO:0043121 | neurotrophin binding | 3.1746 | 4 | yes |
| GO:0048403 | brain-derived neurotrophic factor binding | 3.1746 | 5 | yes |
Biological process
| Term | Name | % | Distance from top the of the tree | Annotated in HAP1_HUMAN |
|---|---|---|---|---|
| GO:0060255 | regulation of macromolecule metabolic process | 42.8571 | 4 | yes |
| GO:0006996 | organelle organization | 41.2698 | 4 | yes |
| GO:0031323 | regulation of cellular metabolic process | 39.6825 | 4 | yes |
| GO:0048522 | positive regulation of cellular process | 39.6825 | 4 | yes |
| GO:0080090 | regulation of primary metabolic process | 39.6825 | 4 | yes |
| GO:0051171 | regulation of nitrogen compound metabolic process | 38.0952 | 4 | yes |
| GO:0008104 | protein localization | 33.3333 | 4 | yes |
| GO:0048523 | negative regulation of cellular process | 33.3333 | 4 | yes |
| GO:0016192 | vesicle-mediated transport | 30.1587 | 4 | yes |
| GO:0010468 | regulation of gene expression | 30.1587 | 5 | no |
| GO:0010646 | regulation of cell communication | 28.5714 | 4 | yes |
| GO:0051246 | regulation of protein metabolic process | 28.5714 | 5 | yes |
| GO:0071702 | organic substance transport | 28.5714 | 4 | yes |
| GO:0071705 | nitrogen compound transport | 28.5714 | 4 | yes |
| GO:0022607 | cellular component assembly | 28.5714 | 4 | no |
| GO:0015031 | protein transport | 26.9841 | 4 | yes |
| GO:0051049 | regulation of transport | 26.9841 | 4 | yes |
| GO:0009892 | negative regulation of metabolic process | 25.3968 | 4 | yes |
| GO:0010605 | negative regulation of macromolecule metabolic process | 25.3968 | 5 | yes |
| GO:0051172 | negative regulation of nitrogen compound metabolic process | 23.8095 | 5 | yes |
| GO:0009893 | positive regulation of metabolic process | 23.8095 | 4 | no |
| GO:0009966 | regulation of signal transduction | 22.2222 | 4 | yes |
| GO:0051128 | regulation of cellular component organization | 22.2222 | 4 | yes |
| GO:0071310 | cellular response to organic substance | 22.2222 | 4 | no |
| GO:0009889 | regulation of biosynthetic process | 22.2222 | 4 | no |
| GO:0010604 | positive regulation of macromolecule metabolic process | 22.2222 | 5 | no |
| GO:0031326 | regulation of cellular biosynthetic process | 22.2222 | 5 | no |
| GO:0006886 | intracellular protein transport | 20.6349 | 4 | yes |
| GO:0031324 | negative regulation of cellular metabolic process | 20.6349 | 5 | yes |
| GO:0010556 | regulation of macromolecule biosynthetic process | 20.6349 | 5 | no |
| GO:0019219 | regulation of nucleobase-containing compound metabolic process | 20.6349 | 5 | no |
| GO:0051050 | positive regulation of transport | 19.0476 | 4 | yes |
| GO:0048584 | positive regulation of response to stimulus | 17.4603 | 4 | yes |
| GO:0023056 | positive regulation of signaling | 15.8730 | 4 | yes |
| GO:0030030 | cell projection organization | 15.8730 | 4 | yes |
| GO:0033043 | regulation of organelle organization | 15.8730 | 5 | yes |
| GO:0051130 | positive regulation of cellular component organization | 15.8730 | 5 | yes |
| GO:0051248 | negative regulation of protein metabolic process | 15.8730 | 6 | yes |
| GO:0010638 | positive regulation of organelle organization | 14.2857 | 6 | yes |
| GO:0010647 | positive regulation of cell communication | 14.2857 | 5 | yes |
| GO:0044087 | regulation of cellular component biogenesis | 14.2857 | 4 | yes |
| GO:0060341 | regulation of cellular localization | 14.2857 | 4 | yes |
| GO:0009967 | positive regulation of signal transduction | 12.6984 | 5 | yes |
| GO:0030705 | cytoskeleton-dependent intracellular transport | 12.6984 | 4 | yes |
| GO:0044089 | positive regulation of cellular component biogenesis | 12.6984 | 5 | yes |
| GO:0045595 | regulation of cell differentiation | 12.6984 | 4 | yes |
| GO:0051046 | regulation of secretion | 12.6984 | 5 | yes |
| GO:0051240 | positive regulation of multicellular organismal process | 12.6984 | 4 | yes |
| GO:0051650 | establishment of vesicle localization | 12.6984 | 4 | yes |
| GO:1903530 | regulation of secretion by cell | 12.6984 | 4 | yes |
| GO:0007005 | mitochondrion organization | 11.1111 | 5 | yes |
| GO:0010970 | transport along microtubule | 11.1111 | 4 | yes |
| GO:0034248 | regulation of cellular amide metabolic process | 11.1111 | 5 | yes |
| GO:0043269 | regulation of ion transport | 11.1111 | 5 | yes |
| GO:0060627 | regulation of vesicle-mediated transport | 11.1111 | 4 | yes |
| GO:0099111 | microtubule-based transport | 11.1111 | 4 | yes |
| GO:2000026 | regulation of multicellular organismal development | 11.1111 | 4 | yes |
| GO:0006605 | protein targeting | 9.5238 | 5 | yes |
| GO:0017157 | regulation of exocytosis | 9.5238 | 5 | yes |
| GO:0032386 | regulation of intracellular transport | 9.5238 | 5 | yes |
| GO:0032886 | regulation of microtubule-based process | 9.5238 | 4 | yes |
| GO:0043270 | positive regulation of ion transport | 9.5238 | 5 | yes |
| GO:0047496 | vesicle transport along microtubule | 9.5238 | 5 | yes |
| GO:0050804 | modulation of chemical synaptic transmission | 9.5238 | 5 | yes |
| GO:0051094 | positive regulation of developmental process | 9.5238 | 4 | yes |
| GO:0072384 | organelle transport along microtubule | 9.5238 | 4 | yes |
| GO:0099177 | regulation of trans-synaptic signaling | 9.5238 | 4 | yes |
| GO:0099518 | vesicle cytoskeletal trafficking | 9.5238 | 5 | yes |
| GO:0007268 | chemical synaptic transmission | 7.9365 | 6 | yes |
| GO:0008088 | axo-dendritic transport | 7.9365 | 5 | yes |
| GO:0008089 | anterograde axonal transport | 7.9365 | 7 | yes |
| GO:0010959 | regulation of metal ion transport | 7.9365 | 6 | yes |
| GO:0022898 | regulation of transmembrane transporter activity | 7.9365 | 4 | yes |
| GO:0031344 | regulation of cell projection organization | 7.9365 | 5 | yes |
| GO:0034762 | regulation of transmembrane transport | 7.9365 | 4 | yes |
| GO:0045597 | positive regulation of cell differentiation | 7.9365 | 5 | yes |
| GO:0098916 | anterograde trans-synaptic signaling | 7.9365 | 5 | yes |
| GO:0098930 | axonal transport | 7.9365 | 6 | yes |
| GO:0099537 | trans-synaptic signaling | 7.9365 | 4 | yes |
| GO:1902115 | regulation of organelle assembly | 7.9365 | 5 | yes |
| GO:0007167 | enzyme-linked receptor protein signaling pathway | 6.3492 | 4 | yes |
| GO:0007169 | transmembrane receptor protein tyrosine kinase signaling pathway | 6.3492 | 5 | yes |
| GO:0007420 | brain development | 6.3492 | 4 | yes |
| GO:0008090 | retrograde axonal transport | 6.3492 | 7 | yes |
| GO:0031346 | positive regulation of cell projection organization | 6.3492 | 6 | yes |
| GO:0032412 | regulation of ion transmembrane transporter activity | 6.3492 | 5 | yes |
| GO:0034249 | negative regulation of cellular amide metabolic process | 6.3492 | 6 | yes |
| GO:0034765 | regulation of ion transmembrane transport | 6.3492 | 5 | yes |
| GO:0046903 | secretion | 6.3492 | 4 | yes |
| GO:0051282 | regulation of sequestering of calcium ion | 6.3492 | 4 | yes |
| GO:0051924 | regulation of calcium ion transport | 6.3492 | 7 | yes |
| GO:0120035 | regulation of plasma membrane bounded cell projection organization | 6.3492 | 6 | yes |
| GO:1901019 | regulation of calcium ion transmembrane transporter activity | 6.3492 | 6 | yes |
| GO:1903169 | regulation of calcium ion transmembrane transport | 6.3492 | 7 | yes |
| GO:1904062 | regulation of cation transmembrane transport | 6.3492 | 6 | yes |
| GO:0022008 | neurogenesis | 4.7619 | 4 | yes |
| GO:0031585 | regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity | 4.7619 | 6 | yes |
| GO:0031587 | positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity | 4.7619 | 6 | yes |
| GO:0032228 | regulation of synaptic transmission, GABAergic | 4.7619 | 6 | yes |
| GO:0032230 | positive regulation of synaptic transmission, GABAergic | 4.7619 | 6 | yes |
| GO:0032411 | positive regulation of transporter activity | 4.7619 | 4 | yes |
| GO:0032414 | positive regulation of ion transmembrane transporter activity | 4.7619 | 5 | yes |
| GO:0034764 | positive regulation of transmembrane transport | 4.7619 | 5 | yes |
| GO:0034767 | positive regulation of ion transmembrane transport | 4.7619 | 6 | yes |
| GO:0045724 | positive regulation of cilium assembly | 4.7619 | 7 | yes |
| GO:0050767 | regulation of neurogenesis | 4.7619 | 6 | yes |
| GO:0050806 | positive regulation of synaptic transmission | 4.7619 | 5 | yes |
| GO:0051279 | regulation of release of sequestered calcium ion into cytosol | 4.7619 | 5 | yes |
| GO:0051281 | positive regulation of release of sequestered calcium ion into cytosol | 4.7619 | 6 | yes |
| GO:0051928 | positive regulation of calcium ion transport | 4.7619 | 6 | yes |
| GO:0051960 | regulation of nervous system development | 4.7619 | 5 | yes |
| GO:0060284 | regulation of cell development | 4.7619 | 5 | yes |
| GO:0060491 | regulation of cell projection assembly | 4.7619 | 5 | yes |
| GO:0120032 | regulation of plasma membrane bounded cell projection assembly | 4.7619 | 6 | yes |
| GO:0120034 | positive regulation of plasma membrane bounded cell projection assembly | 4.7619 | 6 | yes |
| GO:1901021 | positive regulation of calcium ion transmembrane transporter activity | 4.7619 | 6 | yes |
| GO:1902017 | regulation of cilium assembly | 4.7619 | 6 | yes |
| GO:1902117 | positive regulation of organelle assembly | 4.7619 | 6 | yes |
| GO:1904064 | positive regulation of cation transmembrane transport | 4.7619 | 7 | yes |
| GO:1904427 | positive regulation of calcium ion transmembrane transport | 4.7619 | 7 | yes |
| GO:2001257 | regulation of cation channel activity | 4.7619 | 6 | yes |
| GO:2001259 | positive regulation of cation channel activity | 4.7619 | 6 | yes |
| GO:0006887 | exocytosis | 3.1746 | 4 | yes |
| GO:0010720 | positive regulation of cell development | 3.1746 | 6 | yes |
| GO:0019896 | axonal transport of mitochondrion | 3.1746 | 6 | yes |
| GO:0021979 | hypothalamus cell differentiation | 3.1746 | 4 | yes |
| GO:0032899 | regulation of neurotrophin production | 3.1746 | 4 | yes |
| GO:0032901 | positive regulation of neurotrophin production | 3.1746 | 5 | yes |
| GO:0034643 | establishment of mitochondrion localization, microtubule-mediated | 3.1746 | 4 | yes |
| GO:0038179 | neurotrophin signaling pathway | 3.1746 | 4 | yes |
| GO:0042058 | regulation of epidermal growth factor receptor signaling pathway | 3.1746 | 6 | yes |
| GO:0045742 | positive regulation of epidermal growth factor receptor signaling pathway | 3.1746 | 7 | yes |
| GO:0047497 | mitochondrion transport along microtubule | 3.1746 | 5 | yes |
| GO:0048011 | neurotrophin TRK receptor signaling pathway | 3.1746 | 5 | yes |
| GO:0048311 | mitochondrion distribution | 3.1746 | 4 | yes |
| GO:0050769 | positive regulation of neurogenesis | 3.1746 | 6 | yes |
| GO:0051654 | establishment of mitochondrion localization | 3.1746 | 4 | yes |
| GO:0051962 | positive regulation of nervous system development | 3.1746 | 5 | yes |
| GO:0060632 | regulation of microtubule-based movement | 3.1746 | 5 | yes |
| GO:0098957 | anterograde axonal transport of mitochondrion | 3.1746 | 7 | yes |
| GO:1901184 | regulation of ERBB signaling pathway | 3.1746 | 5 | yes |
| GO:1901186 | positive regulation of ERBB signaling pathway | 3.1746 | 6 | yes |
| GO:1902003 | regulation of amyloid-beta formation | 3.1746 | 6 | yes |
| GO:1902430 | negative regulation of amyloid-beta formation | 3.1746 | 7 | yes |
| GO:1902513 | regulation of organelle transport along microtubule | 3.1746 | 6 | yes |
| GO:1902855 | regulation of non-motile cilium assembly | 3.1746 | 7 | yes |
| GO:1902857 | positive regulation of non-motile cilium assembly | 3.1746 | 8 | yes |
| GO:1902991 | regulation of amyloid precursor protein catabolic process | 3.1746 | 6 | yes |
| GO:1902992 | negative regulation of amyloid precursor protein catabolic process | 3.1746 | 7 | yes |
Disease
| Term | Name | % | Distance from top the of the tree | Annotated in HAP1_HUMAN |
|---|---|---|---|---|
| DOID:331 | central nervous system disease | 6.3492 | 3 | no |
| DOID:1289 | neurodegenerative disease | 3.1746 | 4 | no |
All partners
| Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
|---|---|---|---|---|
| HSP74_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| GRIP1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| 1433E_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| HAP1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| HD_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| PCM1_HUMAN | [view interactions] | Low throughput | no | yes |
| KIF5A_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| DCTN1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| NFM_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| HGS_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| KALRN_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| AHI1_HUMAN | [view interactions] | Low throughput | no | yes |
| ATX3_HUMAN | [view interactions] | Low throughput | no | yes |
| KINH_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| KLC1_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| KIF5C_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| ITPR1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| KLC2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| GBRB3_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| DC1I1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| 1433Z_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| SORT_HUMAN | [view interactions] | Low throughput | no | yes |
| NDF1_HUMAN | [view interactions] | Low throughput | no | yes |
| HS71B_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| HS71A_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| CLCB_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| BDNF_HUMAN | [view interactions] | Low throughput | no | yes |
| CCD96_HUMAN | [view interactions] | High throughput | no | no |
| ASPP2_HUMAN | [view interactions] | High throughput | no | yes |
| C2D1A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| P52K_HUMAN | [view interactions] | High throughput | no | yes |
| MLP3A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| BARD1_HUMAN | [view interactions] | High throughput | no | yes |
| LRIF1_HUMAN | [view interactions] | High throughput | no | yes |
| CE126_HUMAN | [view interactions] | High throughput | no | no |
| ZN33B_HUMAN | [view interactions] | High throughput | no | no |
| TBP_HUMAN | [view interactions] | High throughput | no | yes |
| CG025_HUMAN | [view interactions] | High throughput | no | yes |
| CH033_HUMAN | [view interactions] | High throughput | no | yes |
| CDC73_HUMAN | [view interactions] | High throughput | no | yes |
| HMOX2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RS10_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TAF1D_HUMAN | [view interactions] | High throughput | no | yes |
| TNNT1_HUMAN | [view interactions] | High throughput | no | no |
| MECP2_HUMAN | [view interactions] | High throughput | no | yes |
| ZMAT2_HUMAN | [view interactions] | High throughput | no | yes |
| CDK18_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FA50B_HUMAN | [view interactions] | High throughput | no | yes |
| ZN490_HUMAN | [view interactions] | High throughput | no | no |
| C2CD6_HUMAN | [view interactions] | High throughput | no | no |
| ZN124_HUMAN | [view interactions] | High throughput | no | no |
| PRP31_HUMAN | [view interactions] | High throughput | no | yes |
| CA216_HUMAN | [view interactions] | High throughput | no | yes |
| PKN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ZN648_HUMAN | [view interactions] | High throughput | no | no |
| GBRL2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SCNM1_HUMAN | [view interactions] | High throughput | no | no |
| ZFP1_HUMAN | [view interactions] | High throughput | no | no |
| PPR18_HUMAN | [view interactions] | High throughput | no | no |
| ZN575_HUMAN | [view interactions] | High throughput | no | no |
| CCD13_HUMAN | [view interactions] | High throughput | no | no |
| ZN572_HUMAN | [view interactions] | High throughput | no | yes |
| MSGN1_HUMAN | [view interactions] | High throughput | no | no |
| RHPN1_HUMAN | [view interactions] | High throughput | no | yes |
| ZN835_HUMAN | [view interactions] | High throughput | no | no |
| HXB5_HUMAN | [view interactions] | High throughput | no | no |
| ATPK_HUMAN | [view interactions] | High throughput | no | yes |
| CK5P2_HUMAN | [view interactions] | High throughput | no | yes |
| NDUB9_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PFD1_HUMAN | [view interactions] | High throughput | no | yes |
| PSD11_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RS25_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SNAPN_HUMAN | [view interactions] | High throughput | no | yes |
| STX5_HUMAN | [view interactions] | High throughput | no | yes |
| TNNT3_HUMAN | [view interactions] | High throughput | no | no |
| TOM20_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ZNF24_HUMAN | [view interactions] | High throughput | no | yes |
| CBX8_HUMAN | [view interactions] | High throughput | no | yes |
| CO9A2_HUMAN | [view interactions] | High throughput | no | no |
| CRIP1_HUMAN | [view interactions] | High throughput | no | yes |
| KTBL1_HUMAN | [view interactions] | High throughput | no | no |
| CC113_HUMAN | [view interactions] | High throughput | no | no |
| OGA_HUMAN | [view interactions] | High throughput | no | yes |
| ANKMT_HUMAN | [view interactions] | High throughput | no | yes |
| MPP3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NP1L5_HUMAN | [view interactions] | High throughput | no | yes |
| NPS3A_HUMAN | [view interactions] | High throughput | no | yes |
| PDCD7_HUMAN | [view interactions] | High throughput | no | no |
| PPID_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PPOX_HUMAN | [view interactions] | High throughput | no | no |
| RER1_HUMAN | [view interactions] | High throughput | no | yes |
| SAS10_HUMAN | [view interactions] | High throughput | no | yes |
| ZNF20_HUMAN | [view interactions] | High throughput | no | no |
| DDX49_HUMAN | [view interactions] | High throughput | no | no |
| EIF3E_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NOP53_HUMAN | [view interactions] | High throughput | no | yes |
| ZN691_HUMAN | [view interactions] | High throughput | no | yes |
| RT09_HUMAN | [view interactions] | High throughput | no | yes |
| SRSF4_HUMAN | [view interactions] | High throughput | no | yes |
| TI17A_HUMAN | [view interactions] | High throughput | no | yes |
| TSYL1_HUMAN | [view interactions] | High throughput | no | yes |
| APLP1_HUMAN | [view interactions] | High throughput | no | yes |
| LC7L2_HUMAN | [view interactions] | High throughput | no | yes |
| FEZ1_HUMAN | [view interactions] | High throughput | no | no |
| GA45G_HUMAN | [view interactions] | High throughput | no | yes |
| GIT1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KAT7_HUMAN | [view interactions] | High throughput | no | yes |
| KBTB7_HUMAN | [view interactions] | High throughput | no | yes |
| ING5_HUMAN | [view interactions] | High throughput | no | yes |
| GASP2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MIC60_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| IMA1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| BRD7_HUMAN | [view interactions] | High throughput | no | yes |
| KAT5_HUMAN | [view interactions] | High throughput | no | yes |
| VIME_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| NECD_HUMAN | [view interactions] | High throughput | no | no |
| NOD2_HUMAN | [view interactions] | High throughput | no | yes |
| HDAC4_HUMAN | [view interactions] | High throughput | no | yes |
| AEN_HUMAN | [view interactions] | High throughput | no | no |
| PNKP_HUMAN | [view interactions] | High throughput | no | yes |
| RPB1_HUMAN | [view interactions] | High throughput | no | no |
| SYN1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| PABP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HS71L_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| TPM4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DPYL2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ANXA1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ACTG_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ANXA2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| G3P_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| UBC_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| H4_HUMAN | [view interactions] | High throughput | no | yes |
| ARGI1_HUMAN | [view interactions] | High throughput | no | no |
| EF1A1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DDX1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GBB1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PRPS2_HUMAN | [view interactions] | High throughput | no | no |
| ACTB_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| SC6A4_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| TXLNG_HUMAN | [view interactions] | High throughput | no | no |
| HOOK3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| IMPCT_HUMAN | [view interactions] | High throughput | no | yes |
| MYPT1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MKLN1_HUMAN | [view interactions] | High throughput | no | yes |
| NBR1_HUMAN | [view interactions] | High throughput | no | yes |
| NOSIP_HUMAN | [view interactions] | High throughput | no | yes |
| TXLNA_HUMAN | [view interactions] | High throughput | no | yes |
| NFYB_HUMAN | [view interactions] | Computational | no | yes |
| DCTN2_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| DYH7_HUMAN | [view interactions] | Computational | no | no |
| DYH12_HUMAN | [view interactions] | Computational | no | no |
| REPI1_HUMAN | [view interactions] | Computational | no | yes |
| DCTN4_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| ACTY_HUMAN | [view entry] [view interactions] | Computational | yes | no |
| DCTN3_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| DYH5_HUMAN | [view interactions] | Computational | no | no |
| DYH2_HUMAN | [view interactions] | Computational | no | no |
| DCTN6_HUMAN | [view interactions] | Computational | no | no |
| DYH11_HUMAN | [view interactions] | Computational | no | no |
| DYH6_HUMAN | [view interactions] | Computational | no | no |
| DNAI2_HUMAN | [view interactions] | Computational | no | no |
| DCTN5_HUMAN | [view interactions] | Computational | no | yes |
| DNAL1_HUMAN | [view interactions] | Computational | no | no |
| DYH3_HUMAN | [view interactions] | Computational | no | no |
| DYH1_HUMAN | [view interactions] | Computational | no | yes |
| DYH14_HUMAN | [view interactions] | Computational | no | no |
| DYH9_HUMAN | [view interactions] | Computational | no | no |
| NFYC_HUMAN | [view interactions] | Computational | no | no |
| ARP10_HUMAN | [view interactions] | Computational | no | no |
| DNAL4_HUMAN | [view interactions] | Computational | no | yes |
| ACTZ_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| DYH17_HUMAN | [view interactions] | Computational | no | no |