Features Interactions Isoform Disease Linear motifs Fingerprint Network All partners

DCTN1_HUMAN

Plays a key role in dynein-mediated retrograde transport of vesicles and organelles along microtubules by recruiting and tethering dynein to microtubules. Binds to both dynein and microtubules providing a link between specific cargos, microtubules and dynein. Essential for targeting dynein to microtubule plus ends, recruiting dynein to membranous cargos and enhancing dynein processivity (the ability to move along a microtubule for a long distance without falling off the track). Can also act as a brake to slow the dynein motor during motility along the microtubule (PubMed). Can regulate microtubule stability by promoting microtubule formation, nucleation and polymerization and by inhibiting microtubule catastrophe in neurons. Inhibits microtubule catastrophe by binding both to microtubules and to tubulin, leading to enhanced microtubule stability along the axon (PubMed). Plays a role in metaphase spindle orientation (PubMed). Plays a role in centriole cohesion and subdistal appendage organization and function. Its recruitment to the centriole in a KIF3A-dependent manner is essential for the maintenance of centriole cohesion and the formation of subdistal appendage. Also required for microtubule anchoring at the mother centriole (PubMed). Plays a role in primary cilia formation (PubMed). [View more on UniProt]

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Download full PS network for entry.
Position Amino acid Mutation Disease Overlap with binding region
59 Gly Ser Neuronopathy,distalhereditarymotor,7B(HMN7B) -
71 Gly Ala Perrysyndrome(PERRYS) -
71 Gly Glu Perrysyndrome(PERRYS) -
71 Gly Arg Perrysyndrome(PERRYS) -
72 Thr Pro Perrysyndrome(PERRYS) -
74 Gln Pro Perrysyndrome(PERRYS) -
571 Met Thr Amyotrophiclateralsclerosis(ALS) -
785 Arg Trp Amyotrophiclateralsclerosis(ALS) -
1101 Arg Lys Amyotrophiclateralsclerosis(ALS) -
52 Phe Leu Perrysyndrome(PERRYS) -
78 Tyr Cys Perrysyndrome(PERRYS) -

No annotated instance was found. To search for linear motifs, use the ELM prediction server.

Molecular function

Term Name % Distance from the top of the tree Annotated in DCTN1_HUMAN
GO:0043168 anion binding 30.0000 4 no
GO:0000166 nucleotide binding 28.8235 4 no
GO:0017076 purine nucleotide binding 28.8235 5 no
GO:0032555 purine ribonucleotide binding 28.2353 4 no
GO:0035639 purine ribonucleoside triphosphate binding 27.6471 4 no
GO:0030554 adenyl nucleotide binding 22.9412 6 no
GO:0032559 adenyl ribonucleotide binding 22.3529 5 no
GO:0005524 ATP binding 21.7647 5 no
GO:0015631 tubulin binding 18.2353 4 yes
GO:0008017 microtubule binding 17.6471 5 yes
GO:0019900 kinase binding 16.4706 4 yes
GO:0019901 protein kinase binding 15.2941 5 yes
GO:0048156 tau protein binding 3.5294 4 yes

Biological process

Term Name % Distance from top the of the tree Annotated in DCTN1_HUMAN
GO:0048522 positive regulation of cellular process 51.1765 4 yes
GO:0006996 organelle organization 47.0588 4 yes
GO:0051128 regulation of cellular component organization 43.5294 4 yes
GO:0048523 negative regulation of cellular process 42.9412 4 no
GO:0031323 regulation of cellular metabolic process 39.4118 4 no
GO:0060255 regulation of macromolecule metabolic process 39.4118 4 no
GO:0008104 protein localization 38.8235 4 no
GO:0080090 regulation of primary metabolic process 38.2353 4 no
GO:0010646 regulation of cell communication 35.8824 4 no
GO:0022607 cellular component assembly 32.9412 4 yes
GO:0007010 cytoskeleton organization 31.1765 5 yes
GO:0033043 regulation of organelle organization 31.1765 5 yes
GO:0009966 regulation of signal transduction 30.5882 4 no
GO:0009889 regulation of biosynthetic process 28.2353 4 no
GO:0031326 regulation of cellular biosynthetic process 27.6471 5 no
GO:0051246 regulation of protein metabolic process 27.0588 5 no
GO:0071702 organic substance transport 27.0588 4 no
GO:0071705 nitrogen compound transport 27.0588 4 no
GO:0010556 regulation of macromolecule biosynthetic process 27.0588 5 no
GO:0044087 regulation of cellular component biogenesis 27.0588 4 yes
GO:0010468 regulation of gene expression 25.2941 6 no
GO:0009893 positive regulation of metabolic process 24.7059 4 no
GO:0015031 protein transport 24.7059 4 no
GO:0051130 positive regulation of cellular component organization 24.7059 5 yes
GO:0009892 negative regulation of metabolic process 24.1176 4 no
GO:0010605 negative regulation of macromolecule metabolic process 22.9412 5 no
GO:0051049 regulation of transport 22.9412 4 no
GO:0030030 cell projection organization 22.9412 4 yes
GO:0060341 regulation of cellular localization 22.3529 4 no
GO:0051493 regulation of cytoskeleton organization 21.7647 6 yes
GO:0048584 positive regulation of response to stimulus 21.1765 4 no
GO:0031324 negative regulation of cellular metabolic process 21.1765 5 no
GO:0010604 positive regulation of macromolecule metabolic process 20.5882 5 no
GO:0043933 protein-containing complex organization 20.5882 4 no
GO:1902903 regulation of supramolecular fiber organization 18.8235 5 yes
GO:0120036 plasma membrane bounded cell projection organization 18.2353 5 yes
GO:0010638 positive regulation of organelle organization 14.7059 6 yes
GO:0070925 organelle assembly 14.1176 5 yes
GO:0032886 regulation of microtubule-based process 14.1176 4 yes
GO:0043254 regulation of protein-containing complex assembly 14.1176 5 yes
GO:0044089 positive regulation of cellular component biogenesis 13.5294 5 yes
GO:0070507 regulation of microtubule cytoskeleton organization 12.3529 5 yes
GO:0032271 regulation of protein polymerization 12.3529 6 yes
GO:0051726 regulation of cell cycle 12.3529 4 yes
GO:0061024 membrane organization 10.5882 4 yes
GO:0010564 regulation of cell cycle process 9.4118 5 yes
GO:0016482 cytosolic transport 9.4118 4 yes
GO:0022411 cellular component disassembly 9.4118 4 yes
GO:0031110 regulation of microtubule polymerization or depolymerization 9.4118 6 yes
GO:0034330 cell junction organization 9.4118 4 yes
GO:0050807 regulation of synapse organization 9.4118 5 yes
GO:0051650 establishment of vesicle localization 8.8235 4 yes
GO:1902905 positive regulation of supramolecular fiber organization 8.2353 6 yes
GO:0042147 retrograde transport, endosome to Golgi 8.2353 4 yes
GO:0051495 positive regulation of cytoskeleton organization 8.2353 7 yes
GO:1902850 microtubule cytoskeleton organization involved in mitosis 7.6471 4 yes
GO:0120031 plasma membrane bounded cell projection assembly 7.0588 6 yes
GO:0030031 cell projection assembly 7.0588 5 yes
GO:0031113 regulation of microtubule polymerization 7.0588 6 yes
GO:0031334 positive regulation of protein-containing complex assembly 6.4706 6 yes
GO:0032273 positive regulation of protein polymerization 6.4706 7 yes
GO:0031112 positive regulation of microtubule polymerization or depolymerization 5.2941 7 yes
GO:0031116 positive regulation of microtubule polymerization 5.2941 7 yes
GO:0044782 cilium organization 5.2941 5 yes
GO:0050808 synapse organization 5.2941 5 yes
GO:0051293 establishment of spindle localization 5.2941 4 yes
GO:0060271 cilium assembly 4.1176 6 yes
GO:0007399 nervous system development 4.1176 4 yes
GO:0040001 establishment of mitotic spindle localization 4.1176 5 yes
GO:0050905 neuromuscular process 4.1176 4 yes
GO:0051294 establishment of spindle orientation 4.1176 5 yes
GO:0060236 regulation of mitotic spindle organization 3.5294 7 yes
GO:0090224 regulation of spindle organization 3.5294 6 yes
GO:0034453 microtubule anchoring 3.5294 4 yes
GO:0090063 positive regulation of microtubule nucleation 2.9412 8 yes
GO:0106027 neuron projection organization 2.9412 6 yes
GO:0000132 establishment of mitotic spindle orientation 2.9412 6 yes
GO:0007097 nuclear migration 2.9412 4 yes
GO:0010968 regulation of microtubule nucleation 2.9412 7 yes
GO:0072393 microtubule anchoring at microtubule organizing center 2.3529 5 yes
GO:1905515 non-motile cilium assembly 2.3529 7 yes
GO:0034454 microtubule anchoring at centrosome 2.3529 6 yes
GO:0071763 nuclear membrane organization 1.7647 5 yes
GO:0099558 maintenance of synapse structure 1.7647 6 yes
GO:1904396 regulation of neuromuscular junction development 1.7647 6 yes
GO:1990535 neuron projection maintenance 1.7647 7 yes
GO:0007528 neuromuscular junction development 1.7647 6 yes
GO:0030397 membrane disassembly 1.7647 5 yes
GO:0032400 melanosome localization 1.7647 5 yes
GO:0032401 establishment of melanosome localization 1.7647 6 yes
GO:0032402 melanosome transport 1.7647 5 yes
GO:0034331 cell junction maintenance 1.7647 5 yes
GO:0043954 cellular component maintenance 1.7647 4 yes
GO:0051081 nuclear membrane disassembly 1.7647 6 yes
GO:0051875 pigment granule localization 1.7647 4 yes
GO:0051904 pigment granule transport 1.7647 4 yes
GO:0051905 establishment of pigment granule localization 1.7647 5 yes
GO:1904398 positive regulation of neuromuscular junction development 1.1765 6 yes

Disease

No data found.

Uniprot ID Details Highest evidence Localizing into PSD HPA (protein expression in neurons)
HDAC6_HUMAN [view interactions] Low throughput no yes
NDC80_HUMAN [view interactions] Low throughput no no
NUMA1_HUMAN [view interactions] Low throughput no yes
BAG3_HUMAN [view entry] [view interactions] Low throughput yes no
IQEC1_HUMAN [view entry] [view interactions] Low throughput yes yes
CTIF_HUMAN [view interactions] Low throughput no yes
ECM29_HUMAN [view interactions] Low throughput no no
NDEL1_HUMAN [view entry] [view interactions] Low throughput yes yes
MARE3_HUMAN [view entry] [view interactions] Low throughput yes yes
LIS1_HUMAN [view entry] [view interactions] Low throughput yes yes
DYST_HUMAN [view entry] [view interactions] Low throughput yes yes
KIF11_HUMAN [view interactions] Low throughput no yes
FBXL5_HUMAN [view interactions] Low throughput no yes
RBL2_HUMAN [view interactions] Low throughput no yes
VIME_HUMAN [view entry] [view interactions] Low throughput yes no
PLK1_HUMAN [view interactions] Low throughput no yes
GRB2_HUMAN [view entry] [view interactions] Low throughput yes yes
EPB41_HUMAN [view entry] [view interactions] Low throughput yes no
SPTB2_HUMAN [view entry] [view interactions] Low throughput yes yes
DYL1_HUMAN [view entry] [view interactions] Low throughput yes no
BBS4_HUMAN [view interactions] Low throughput no no
DC1I1_HUMAN [view entry] [view interactions] Low throughput yes yes
HAP1_HUMAN [view entry] [view interactions] Low throughput yes yes
BICL1_HUMAN [view interactions] Low throughput no yes
BICD2_HUMAN [view interactions] Low throughput no yes
DCTN2_HUMAN [view entry] [view interactions] Low throughput yes yes
DCTN4_HUMAN [view entry] [view interactions] Low throughput yes yes
DCTN1_HUMAN [view entry] [view interactions] Low throughput yes yes
ACTY_HUMAN [view entry] [view interactions] Low throughput yes no
MARE1_HUMAN [view entry] [view interactions] Low throughput yes yes
DYHC1_HUMAN [view entry] [view interactions] Low throughput yes yes
SNX6_HUMAN [view entry] [view interactions] Low throughput yes no
AP5Z1_HUMAN [view interactions] Low throughput no yes
KIF3A_HUMAN [view entry] [view interactions] Low throughput yes yes
TAU_HUMAN [view entry] [view interactions] Low throughput yes yes
RAB6A_HUMAN [view entry] [view interactions] Low throughput yes yes
DC2L1_HUMAN [view interactions] Low throughput no no
CLIP1_HUMAN [view entry] [view interactions] Low throughput yes yes
BICD1_HUMAN [view interactions] Low throughput no yes
TBA3D_HUMAN [view interactions] Low throughput no no
DAZL_HUMAN [view interactions] Low throughput no no
SPHK2_HUMAN [view interactions] Low throughput no no
KIF5A_HUMAN [view entry] [view interactions] Low throughput yes yes
NUDC_HUMAN [view interactions] Low throughput no yes
KINH_HUMAN [view entry] [view interactions] Low throughput yes no
EF1A1_HUMAN [view entry] [view interactions] Low throughput yes yes
MISP_HUMAN [view interactions] Low throughput no no
KASH5_HUMAN [view interactions] Low throughput no yes
SNX4_HUMAN [view entry] [view interactions] Low throughput yes yes
CYFP1_HUMAN [view entry] [view interactions] High throughput yes yes
TBB4B_HUMAN [view interactions] High throughput no yes
MYCB2_HUMAN [view entry] [view interactions] High throughput yes no
1433B_HUMAN [view entry] [view interactions] High throughput yes yes
SHAN3_HUMAN [view entry] [view interactions] High throughput yes no
1433E_HUMAN [view entry] [view interactions] High throughput yes yes
RYBP_HUMAN [view interactions] High throughput no no
1433F_HUMAN [view entry] [view interactions] High throughput yes yes
HCN1_HUMAN [view entry] [view interactions] High throughput yes yes
1433Z_HUMAN [view entry] [view interactions] High throughput yes yes
CK5P2_HUMAN [view interactions] High throughput no yes
AURKA_HUMAN [view entry] [view interactions] High throughput yes no
CEP63_HUMAN [view interactions] High throughput no yes
PRKN_HUMAN [view entry] [view interactions] High throughput yes yes
ZRAN1_HUMAN [view interactions] High throughput no yes
BAP1_HUMAN [view interactions] High throughput no yes
HAPR1_HUMAN [view interactions] High throughput no yes
PGAM1_HUMAN [view entry] [view interactions] High throughput yes yes
DOT1L_HUMAN [view interactions] High throughput no yes
STAT1_HUMAN [view entry] [view interactions] High throughput yes no
MEN1_HUMAN [view interactions] High throughput no yes
FXR1_HUMAN [view entry] [view interactions] High throughput yes yes
HSP7C_HUMAN [view entry] [view interactions] High throughput yes yes
HXA1_HUMAN [view interactions] High throughput no no
HS71B_HUMAN [view entry] [view interactions] High throughput yes yes
CDK1_HUMAN [view interactions] High throughput no no
HS71A_HUMAN [view entry] [view interactions] High throughput yes yes
CEP76_HUMAN [view interactions] High throughput no yes
R113A_HUMAN [view interactions] High throughput no yes
CUL3_HUMAN [view entry] [view interactions] High throughput yes yes
RUFY1_HUMAN [view interactions] High throughput no yes
IRF3_HUMAN [view interactions] High throughput no yes
TRI67_HUMAN [view interactions] High throughput no no
CAPZB_HUMAN [view entry] [view interactions] High throughput yes yes
RPN2_HUMAN [view entry] [view interactions] High throughput yes yes
CI072_HUMAN [view entry] [view interactions] High throughput yes no
STIP1_HUMAN [view entry] [view interactions] High throughput yes yes
UBP48_HUMAN [view interactions] High throughput no yes
ENOB_HUMAN [view entry] [view interactions] High throughput yes no
ADA10_HUMAN [view entry] [view interactions] High throughput yes yes
PRPK_HUMAN [view interactions] High throughput no yes
EGFR_HUMAN [view interactions] High throughput no no
TNIK_HUMAN [view entry] [view interactions] High throughput yes yes
TOP3B_HUMAN [view interactions] High throughput no no
CD2AP_HUMAN [view interactions] High throughput no no
MOB3C_HUMAN [view interactions] High throughput no no
LCOR_HUMAN [view interactions] High throughput no yes
EZH2_HUMAN [view interactions] High throughput no no
RICTR_HUMAN [view interactions] High throughput no yes
FEZ2_HUMAN [view interactions] High throughput no yes
UBE2H_HUMAN [view interactions] High throughput no yes
MTEF1_HUMAN [view interactions] High throughput no yes
TNIP1_HUMAN [view interactions] High throughput no yes
SKAP_HUMAN [view interactions] High throughput no yes
FAS_HUMAN [view entry] [view interactions] High throughput yes no
NP1L1_HUMAN [view entry] [view interactions] High throughput yes yes
NF1_HUMAN [view entry] [view interactions] High throughput yes no
ADRO_HUMAN [view interactions] High throughput no no
NMT1_HUMAN [view interactions] High throughput no yes
ERLN2_HUMAN [view entry] [view interactions] High throughput yes yes
S30BP_HUMAN [view interactions] High throughput no yes
MAP7_HUMAN [view interactions] High throughput no yes
RPB2_HUMAN [view interactions] High throughput no yes
IF2B2_HUMAN [view interactions] High throughput no yes
MCM3_HUMAN [view interactions] High throughput no no
NNTM_HUMAN [view entry] [view interactions] High throughput yes yes
RN168_HUMAN [view interactions] High throughput no no
RAB8A_HUMAN [view entry] [view interactions] High throughput yes no
FLNC_HUMAN [view entry] [view interactions] High throughput yes no
BTF3_HUMAN [view interactions] High throughput no yes
MCCA_HUMAN [view entry] [view interactions] High throughput yes yes
MAP1S_HUMAN [view interactions] High throughput no no
RANB9_HUMAN [view entry] [view interactions] High throughput yes yes
EBP2_HUMAN [view interactions] High throughput no yes
STRN4_HUMAN [view entry] [view interactions] High throughput yes yes
MLP3B_HUMAN [view interactions] High throughput no yes
CKP2L_HUMAN [view interactions] High throughput no yes
C2D1B_HUMAN [view interactions] High throughput no yes
CLH1_HUMAN [view entry] [view interactions] High throughput yes yes
CCAR1_HUMAN [view interactions] High throughput no yes
MAP9_HUMAN [view interactions] High throughput no no
DNJA2_HUMAN [view entry] [view interactions] High throughput yes yes
HYOU1_HUMAN [view interactions] High throughput no yes
PSB6_HUMAN [view entry] [view interactions] High throughput yes yes
EMAL4_HUMAN [view interactions] High throughput no yes
PSD11_HUMAN [view entry] [view interactions] High throughput yes yes
BT3L4_HUMAN [view interactions] High throughput no yes
SF3A3_HUMAN [view interactions] High throughput no yes
LUZP1_HUMAN [view interactions] High throughput no yes
SF3B3_HUMAN [view interactions] High throughput no yes
NP1L4_HUMAN [view entry] [view interactions] High throughput yes yes
EIF2A_HUMAN [view interactions] High throughput no yes
CPVL_HUMAN [view interactions] High throughput no no
PACN3_HUMAN [view interactions] High throughput no yes
AGK_HUMAN [view entry] [view interactions] High throughput yes yes
POP1_HUMAN [view interactions] High throughput no no
PSMD7_HUMAN [view interactions] High throughput no yes
RAGP1_HUMAN [view entry] [view interactions] High throughput yes yes
RAB35_HUMAN [view entry] [view interactions] High throughput yes yes
SEC13_HUMAN [view entry] [view interactions] High throughput yes yes
DCLK1_HUMAN [view entry] [view interactions] High throughput yes yes
VP26A_HUMAN [view entry] [view interactions] High throughput yes no
SKA3_HUMAN [view interactions] High throughput no no
VPS29_HUMAN [view entry] [view interactions] High throughput yes yes
TM256_HUMAN [view interactions] High throughput no no
VPS35_HUMAN [view entry] [view interactions] High throughput yes yes
IPO7_HUMAN [view entry] [view interactions] High throughput yes yes
ZN207_HUMAN [view interactions] High throughput no yes
MTUS1_HUMAN [view interactions] High throughput no no
CKAP5_HUMAN [view entry] [view interactions] High throughput yes yes
DYN2_HUMAN [view entry] [view interactions] High throughput yes yes
TPR_HUMAN [view interactions] High throughput no yes
C170B_HUMAN [view interactions] High throughput no yes
SNX1_HUMAN [view entry] [view interactions] High throughput yes yes
EFTS_HUMAN [view interactions] High throughput no no
SNX2_HUMAN [view entry] [view interactions] High throughput yes no
LASP1_HUMAN [view entry] [view interactions] High throughput yes yes
SNX27_HUMAN [view entry] [view interactions] High throughput yes no
EMAL1_HUMAN [view interactions] High throughput no no
USO1_HUMAN [view entry] [view interactions] High throughput yes yes
ZN622_HUMAN [view interactions] High throughput no yes
NUP85_HUMAN [view interactions] High throughput no yes
ZC3HF_HUMAN [view interactions] High throughput no yes
SNX5_HUMAN [view entry] [view interactions] High throughput yes yes
PSDE_HUMAN [view entry] [view interactions] High throughput yes yes
EIF3D_HUMAN [view interactions] High throughput no yes
CE170_HUMAN [view interactions] High throughput no yes
SNX3_HUMAN [view entry] [view interactions] High throughput yes no
WDHD1_HUMAN [view interactions] High throughput no no
MA7D2_HUMAN [view interactions] High throughput no yes
MTA2_HUMAN [view interactions] High throughput no yes
CLAP1_HUMAN [view entry] [view interactions] High throughput yes yes
SMC2_HUMAN [view interactions] High throughput no yes
GTSE1_HUMAN [view interactions] High throughput no no
GLU2B_HUMAN [view interactions] High throughput no yes
MA7D3_HUMAN [view interactions] High throughput no no
MCM4_HUMAN [view interactions] High throughput no yes
MTAP2_HUMAN [view entry] [view interactions] High throughput yes yes
MCM7_HUMAN [view interactions] High throughput no no
SKA2_HUMAN [view interactions] High throughput no no
MATR3_HUMAN [view interactions] High throughput no yes
GPTC1_HUMAN [view interactions] High throughput no yes
NASP_HUMAN [view interactions] High throughput no yes
HMMR_HUMAN [view interactions] High throughput no yes
RAB7A_HUMAN [view entry] [view interactions] High throughput yes yes
CKAP2_HUMAN [view interactions] High throughput no yes
IMA1_HUMAN [view entry] [view interactions] High throughput yes yes
CCNB1_HUMAN [view interactions] High throughput no no
MSH6_HUMAN [view interactions] High throughput no yes
MARE2_HUMAN [view entry] [view interactions] High throughput yes yes
HNRPU_HUMAN [view interactions] High throughput no yes
NUBP2_HUMAN [view interactions] High throughput no yes
SRSF1_HUMAN [view interactions] High throughput no yes
IPO9_HUMAN [view interactions] High throughput no no
FLII_HUMAN [view entry] [view interactions] High throughput yes yes
SRSF2_HUMAN [view interactions] High throughput no yes
G3BP1_HUMAN [view interactions] High throughput no yes
SPAG5_HUMAN [view interactions] High throughput no yes
CAPR1_HUMAN [view entry] [view interactions] High throughput yes yes
CAMP2_HUMAN [view interactions] High throughput no yes
MCM6_HUMAN [view interactions] High throughput no yes
RAB2A_HUMAN [view entry] [view interactions] High throughput yes yes
GANAB_HUMAN [view interactions] High throughput no yes
PKHA5_HUMAN [view entry] [view interactions] High throughput yes yes
CHD4_HUMAN [view interactions] High throughput no yes
AURKB_HUMAN [view interactions] High throughput no yes
CND2_HUMAN [view interactions] High throughput no no
C560_HUMAN [view interactions] High throughput no no
CND1_HUMAN [view interactions] High throughput no yes
LONM_HUMAN [view entry] [view interactions] High throughput yes yes
P4R3A_HUMAN [view interactions] High throughput no yes
TRI36_HUMAN [view interactions] High throughput no no
TM10A_HUMAN [view interactions] High throughput no no
EMC3_HUMAN [view interactions] High throughput no yes
TBCD5_HUMAN [view interactions] High throughput no yes
KIF2A_HUMAN [view entry] [view interactions] High throughput yes yes
HDAC2_HUMAN [view interactions] High throughput no yes
MA7D1_HUMAN [view entry] [view interactions] High throughput yes no
VPS50_HUMAN [view interactions] High throughput no yes
QCR1_HUMAN [view entry] [view interactions] High throughput yes yes
RBGPR_HUMAN [view entry] [view interactions] High throughput yes yes
HAUS8_HUMAN [view interactions] High throughput no yes
GCP60_HUMAN [view interactions] High throughput no yes
DRC5_HUMAN [view interactions] High throughput no no
SMC4_HUMAN [view interactions] High throughput no yes
NIN_HUMAN [view interactions] High throughput no no
PP4R2_HUMAN [view interactions] High throughput no yes
GA2L3_HUMAN [view interactions] High throughput no no
ANFY1_HUMAN [view entry] [view interactions] High throughput yes yes
SLAI2_HUMAN [view interactions] High throughput no no
RNF14_HUMAN [view interactions] High throughput no yes
HAUS7_HUMAN [view interactions] High throughput no no
ZO2_HUMAN [view entry] [view interactions] High throughput yes no
CFA97_HUMAN [view interactions] High throughput no yes
CFDP1_HUMAN [view interactions] High throughput no yes
CHTOP_HUMAN [view interactions] High throughput no yes
HECD1_HUMAN [view interactions] High throughput no yes
NEDD1_HUMAN [view interactions] High throughput no yes
EIF3L_HUMAN [view interactions] High throughput no yes
DLGP5_HUMAN [view interactions] High throughput no no
UBP15_HUMAN [view entry] [view interactions] High throughput yes yes
ARHG2_HUMAN [view entry] [view interactions] High throughput yes yes
STK24_HUMAN [view interactions] High throughput no yes
LTV1_HUMAN [view interactions] High throughput no yes
GBF1_HUMAN [view interactions] High throughput no yes
KIF14_HUMAN [view interactions] High throughput no no
HOOK1_HUMAN [view interactions] High throughput no no
YTHD1_HUMAN [view interactions] High throughput no no
HS12B_HUMAN [view interactions] High throughput no yes
GPX1_HUMAN [view entry] [view interactions] High throughput yes yes
ABCF3_HUMAN [view entry] [view interactions] High throughput yes yes
PAPOG_HUMAN [view interactions] High throughput no yes
ANR28_HUMAN [view interactions] High throughput no no
SRP09_HUMAN [view interactions] High throughput no no
ANR52_HUMAN [view interactions] High throughput no yes
TDRD3_HUMAN [view interactions] High throughput no yes
APC_HUMAN [view entry] [view interactions] High throughput yes no
TTF2_HUMAN [view interactions] High throughput no yes
RHG21_HUMAN [view entry] [view interactions] High throughput yes yes
DCDC2_HUMAN [view interactions] High throughput no yes
CAMP3_HUMAN [view interactions] High throughput no no
C2D1A_HUMAN [view entry] [view interactions] High throughput yes yes
CCSE2_HUMAN [view interactions] High throughput no yes
HYPK_HUMAN [view interactions] High throughput no no
CDC27_HUMAN [view interactions] High throughput no yes
NACAM_HUMAN [view interactions] High throughput no no
CENPJ_HUMAN [view interactions] High throughput no no
NDUA5_HUMAN [view entry] [view interactions] High throughput yes yes
CP131_HUMAN [view interactions] High throughput no no
CAMP1_HUMAN [view interactions] High throughput no yes
CE162_HUMAN [view interactions] High throughput no yes
CEP44_HUMAN [view interactions] High throughput no yes
CE350_HUMAN [view interactions] High throughput no yes
CEP41_HUMAN [view interactions] High throughput no yes
CEP55_HUMAN [view interactions] High throughput no yes
SKA1_HUMAN [view interactions] High throughput no yes
CEP72_HUMAN [view interactions] High throughput no yes
DCLK2_HUMAN [view entry] [view interactions] High throughput yes yes
DHX57_HUMAN [view interactions] High throughput no no
YTDC2_HUMAN [view interactions] High throughput no no
DJC21_HUMAN [view interactions] High throughput no yes
TSR1_HUMAN [view interactions] High throughput no no
EDF1_HUMAN [view interactions] High throughput no yes
PRC1_HUMAN [view interactions] High throughput no yes
ESPL1_HUMAN [view interactions] High throughput no yes
FA83D_HUMAN [view interactions] High throughput no no
F161A_HUMAN [view interactions] High throughput no no
ANXA1_HUMAN [view entry] [view interactions] High throughput yes no
GEN_HUMAN [view interactions] High throughput no yes
TBCEL_HUMAN [view interactions] High throughput no yes
GKAP1_HUMAN [view interactions] High throughput no no
TTK_HUMAN [view interactions] High throughput no yes
JKIP1_HUMAN [view interactions] High throughput no no
NPL4_HUMAN [view interactions] High throughput no yes
MACF1_HUMAN [view entry] [view interactions] High throughput yes yes
DVL1_HUMAN [view entry] [view interactions] High throughput yes yes
MAP1A_HUMAN [view entry] [view interactions] High throughput yes yes
CLAP2_HUMAN [view entry] [view interactions] High throughput yes no
MAP4_HUMAN [view entry] [view interactions] High throughput yes no
HAUS4_HUMAN [view interactions] High throughput no yes
MPP9_HUMAN [view interactions] High throughput no yes
MARK2_HUMAN [view entry] [view interactions] High throughput yes yes
NAV1_HUMAN [view interactions] High throughput no yes
NAA10_HUMAN [view interactions] High throughput no yes
NCK5L_HUMAN [view interactions] High throughput no yes
ZC21A_HUMAN [view interactions] High throughput no yes
NUF2_HUMAN [view interactions] High throughput no no
NEBL_HUMAN [view entry] [view interactions] High throughput yes no
PP6R1_HUMAN [view interactions] High throughput no no
YTHD2_HUMAN [view interactions] High throughput no yes
PSRC1_HUMAN [view interactions] High throughput no no
DC1I2_HUMAN [view entry] [view interactions] High throughput yes yes
SPD2B_HUMAN [view interactions] High throughput no no
LS14B_HUMAN [view interactions] High throughput no yes
SLAI1_HUMAN [view interactions] High throughput no no
MTCL2_HUMAN [view interactions] High throughput no yes
HAUS6_HUMAN [view interactions] High throughput no yes
CYTSB_HUMAN [view entry] [view interactions] High throughput yes yes
CC124_HUMAN [view entry] [view interactions] High throughput yes yes
CYTSA_HUMAN [view interactions] High throughput no yes
MTPN_HUMAN [view interactions] High throughput no yes
SPICE_HUMAN [view interactions] High throughput no yes
SP16H_HUMAN [view interactions] High throughput no yes
SYNJ2_HUMAN [view entry] [view interactions] High throughput yes yes
RENT1_HUMAN [view entry] [view interactions] High throughput yes yes
TMM79_HUMAN [view interactions] High throughput no no
SPC24_HUMAN [view interactions] High throughput no no
TRI26_HUMAN [view interactions] High throughput no yes
STK26_HUMAN [view interactions] High throughput no no
TITIN_HUMAN [view interactions] High throughput no no
PDZ11_HUMAN [view interactions] High throughput no yes
TBB3_HUMAN [view entry] [view interactions] High throughput yes yes
ABRAL_HUMAN [view interactions] High throughput no yes
TXNL1_HUMAN [view entry] [view interactions] High throughput yes yes
NAA15_HUMAN [view interactions] High throughput no yes
UBE2O_HUMAN [view interactions] High throughput no yes
KIF2C_HUMAN [view entry] [view interactions] High throughput yes no
WDR62_HUMAN [view interactions] High throughput no no
LMTK1_HUMAN [view interactions] High throughput no yes
Z3H7A_HUMAN [view interactions] High throughput no no
KCC2A_HUMAN [view entry] [view interactions] High throughput yes yes
CC138_HUMAN [view interactions] High throughput no yes
NINL_HUMAN [view interactions] High throughput no yes
DHX29_HUMAN [view interactions] High throughput no yes
AHI1_HUMAN [view interactions] High throughput no yes
DIAP3_HUMAN [view interactions] High throughput no no
ENSA_HUMAN [view interactions] High throughput no yes
HAUS5_HUMAN [view interactions] High throughput no yes
IBTK_HUMAN [view interactions] High throughput no yes
MED14_HUMAN [view interactions] High throughput no no
IFT74_HUMAN [view interactions] High throughput no yes
DTBP1_HUMAN [view entry] [view interactions] High throughput yes yes
IPO8_HUMAN [view interactions] High throughput no no
NECD_HUMAN [view interactions] High throughput no no
SKT_HUMAN [view entry] [view interactions] High throughput yes yes
KIF1B_HUMAN [view entry] [view interactions] High throughput yes yes
NOD2_HUMAN [view interactions] High throughput no yes
KIF7_HUMAN [view interactions] High throughput no yes
OFD1_HUMAN [view interactions] High throughput no yes
PAK4_HUMAN [view interactions] High throughput no yes
PDLI3_HUMAN [view interactions] High throughput no no
AP2B1_HUMAN [view entry] [view interactions] High throughput yes yes
SH319_HUMAN [view interactions] High throughput no no
Z512B_HUMAN [view interactions] High throughput no yes
REN3B_HUMAN [view interactions] High throughput no yes
DISC1_HUMAN [view entry] [view interactions] High throughput yes no
NAA40_HUMAN [view interactions] High throughput no no
BBS1_HUMAN [view interactions] High throughput no no
SMUF1_HUMAN [view interactions] High throughput no yes
CCNF_HUMAN [view interactions] High throughput no no
BICL2_HUMAN [view interactions] High throughput no no
KDM1A_HUMAN [view interactions] High throughput no yes
AKT1_HUMAN [view entry] [view interactions] High throughput yes yes
UBC_HUMAN [view entry] [view interactions] High throughput yes yes
HDAC1_HUMAN [view interactions] High throughput no no
CDC37_HUMAN [view interactions] High throughput no yes
FBXW4_HUMAN [view interactions] High throughput no no
RCOR1_HUMAN [view interactions] High throughput no yes
K0408_HUMAN [view entry] [view interactions] High throughput yes no
LGR4_HUMAN [view interactions] High throughput no yes
RFA2_HUMAN [view interactions] High throughput no yes
MOV10_HUMAN [view interactions] High throughput no no
RFA3_HUMAN [view interactions] High throughput no yes
NEK2_HUMAN [view interactions] High throughput no no
NXF1_HUMAN [view interactions] High throughput no yes
WWTR1_HUMAN [view interactions] High throughput no yes
PFD1_HUMAN [view interactions] High throughput no yes
EED_HUMAN [view interactions] High throughput no yes
SYNPO_HUMAN [view entry] [view interactions] High throughput yes no
PP1A_HUMAN [view entry] [view interactions] High throughput yes yes
NTRK1_HUMAN [view interactions] High throughput no yes
CENPE_HUMAN [view interactions] High throughput no no
HSPB2_HUMAN [view interactions] High throughput no yes
KI16B_HUMAN [view interactions] High throughput no yes
CRYAB_HUMAN [view entry] [view interactions] High throughput yes no
DERL1_HUMAN [view interactions] High throughput no yes
SPTCS_HUMAN [view interactions] High throughput no yes
ABCG1_HUMAN [view interactions] High throughput no yes
MYO6_HUMAN [view entry] [view interactions] High throughput yes no
DUS12_HUMAN [view interactions] High throughput no no
FTM_HUMAN [view interactions] High throughput no yes
DS13A_HUMAN [view interactions] High throughput no no
KLHL2_HUMAN [view interactions] High throughput no no
DCTN3_HUMAN [view entry] [view interactions] High throughput yes yes
MIPEP_HUMAN [view interactions] High throughput no yes
DC1L1_HUMAN [view entry] [view interactions] High throughput yes yes
RIC8A_HUMAN [view entry] [view interactions] High throughput yes no
KCTD5_HUMAN [view interactions] High throughput no no
DUSTY_HUMAN [view interactions] High throughput no yes
MYO19_HUMAN [view interactions] High throughput no yes
INAVA_HUMAN [view interactions] High throughput no yes
DLRB1_HUMAN [view entry] [view interactions] High throughput yes no
PDGFD_HUMAN [view interactions] High throughput no no
COR1C_HUMAN [view entry] [view interactions] High throughput yes yes
AROS_HUMAN [view interactions] High throughput no yes
ACTZ_HUMAN [view entry] [view interactions] High throughput yes yes
MERB1_HUMAN [view interactions] High throughput no yes
ARP10_HUMAN [view interactions] High throughput no no
ACTA_HUMAN [view interactions] High throughput no no
TRIPB_HUMAN [view interactions] High throughput no yes
CYLD_HUMAN [view entry] [view interactions] High throughput yes yes
TRI25_HUMAN [view interactions] High throughput no yes
CP250_HUMAN [view interactions] High throughput no no
UBE2A_HUMAN [view interactions] High throughput no no
RT12_HUMAN [view interactions] High throughput no yes
HEY1_HUMAN [view interactions] High throughput no yes
CEP83_HUMAN [view interactions] High throughput no yes
BRCA1_HUMAN [view interactions] High throughput no yes
ANKL2_HUMAN [view interactions] High throughput no yes
TES_HUMAN [view interactions] High throughput no yes
QCR8_HUMAN [view interactions] High throughput no yes
KIBRA_HUMAN [view entry] [view interactions] High throughput yes yes
CAZA1_HUMAN [view entry] [view interactions] High throughput yes yes
ZN598_HUMAN [view interactions] High throughput no no
DCTN6_HUMAN [view interactions] High throughput no no
PCBP1_HUMAN [view entry] [view interactions] High throughput yes yes
DCTN5_HUMAN [view interactions] High throughput no yes
EGLN3_HUMAN [view interactions] High throughput no no
CAZA2_HUMAN [view entry] [view interactions] High throughput yes yes
U5S1_HUMAN [view interactions] High throughput no yes
UBC12_HUMAN [view entry] [view interactions] High throughput yes yes
PTSS1_HUMAN [view interactions] High throughput no no
TNIP2_HUMAN [view interactions] High throughput no yes
ESR2_HUMAN [view interactions] High throughput no no
SC16A_HUMAN [view interactions] High throughput no yes
HEXI1_HUMAN [view interactions] High throughput no yes
MEPCE_HUMAN [view interactions] High throughput no yes
MYO1C_HUMAN [view entry] [view interactions] High throughput yes yes
LARP7_HUMAN [view interactions] High throughput no yes
TRI29_HUMAN [view interactions] High throughput no no
RN181_HUMAN [view interactions] High throughput no no
NEB2_HUMAN [view entry] [view interactions] High throughput yes yes
H4_HUMAN [view interactions] High throughput no yes
PRD16_HUMAN [view interactions] High throughput no no
H2B1B_HUMAN [view interactions] High throughput no yes
MECOM_HUMAN [view interactions] High throughput no yes
GRWD1_HUMAN [view interactions] High throughput no no
LRRK2_HUMAN [view interactions] High throughput no yes
VIR_HUMAN [view interactions] High throughput no yes
MOT11_HUMAN [view interactions] High throughput no no
ACTC_HUMAN [view interactions] High throughput no no
TRPV1_HUMAN [view entry] [view interactions] High throughput yes no
DC1L2_HUMAN [view entry] [view interactions] High throughput yes yes
DYLT1_HUMAN [view interactions] High throughput no no
CFTR_HUMAN [view interactions] High throughput no no
DAPLE_HUMAN [view interactions] High throughput no yes
GRDN_HUMAN [view interactions] High throughput no no
HOOK3_HUMAN [view entry] [view interactions] High throughput yes yes
PEX14_HUMAN [view interactions] High throughput no yes
ATX1_HUMAN [view interactions] High throughput no yes
PI4KB_HUMAN [view interactions] High throughput no yes
APEX1_HUMAN [view interactions] High throughput no yes
TRI63_HUMAN [view interactions] High throughput no no
BIRC3_HUMAN [view interactions] High throughput no no
TWF1_HUMAN [view entry] [view interactions] High throughput yes no
STAU1_HUMAN [view entry] [view interactions] High throughput yes yes
BTBD8_HUMAN [view interactions] High throughput no yes
TIF1B_HUMAN [view interactions] High throughput no yes
PKHA4_HUMAN [view interactions] High throughput no yes
CTRO_HUMAN [view entry] [view interactions] High throughput yes yes
CASP4_HUMAN [view interactions] High throughput no yes
KI20A_HUMAN [view interactions] High throughput no yes
MAGA6_HUMAN [view interactions] High throughput no no
MK01_HUMAN [view entry] [view interactions] High throughput yes yes
AKTIP_HUMAN [view interactions] High throughput no yes
MYC_HUMAN [view interactions] High throughput no yes
MT21E_HUMAN [view interactions] High throughput no no
ARF6_HUMAN [view entry] [view interactions] High throughput yes yes
CUL4A_HUMAN [view interactions] High throughput no no
VHL_HUMAN [view entry] [view interactions] High throughput yes yes
RIGI_HUMAN [view interactions] High throughput no yes
RFXK_HUMAN [view interactions] High throughput no yes
UFL1_HUMAN [view interactions] High throughput no yes
GSTK1_HUMAN [view entry] [view interactions] High throughput yes yes
FZR1_HUMAN [view interactions] High throughput no no
5MP2_HUMAN [view interactions] High throughput no yes
SEP14_HUMAN [view interactions] High throughput no no
CIAO1_HUMAN [view interactions] High throughput no yes
ZKSC1_HUMAN [view interactions] High throughput no yes
JIP3_HUMAN [view entry] [view interactions] High throughput yes yes
FBXW7_HUMAN [view interactions] High throughput no yes
SNW1_HUMAN [view interactions] High throughput no yes
FBX32_HUMAN [view interactions] High throughput no no
JUN_HUMAN [view interactions] High throughput no yes
ACTB_HUMAN [view entry] [view interactions] High throughput yes no
CE290_HUMAN [view interactions] High throughput no no
ACTG_HUMAN [view entry] [view interactions] High throughput yes yes
AAPK1_HUMAN [view interactions] High throughput no no
AGAP3_HUMAN [view entry] [view interactions] High throughput yes yes
AAKB1_HUMAN [view interactions] High throughput no yes
RHGBA_HUMAN [view interactions] High throughput no yes
DYL2_HUMAN [view entry] [view interactions] High throughput yes no
DDR1_HUMAN [view interactions] High throughput no yes
ESTD_HUMAN [view interactions] High throughput no yes