APC_HUMAN
Evidence for PS localization
Functions
Tumor suppressor. Promotes rapid degradation of CTNNB1 and participates in Wnt signaling as a negative regulator. APC activity is correlated with its phosphorylation state. Activates the GEF activity of SPATA13 and ARHGEF4. Plays a role in hepatocyte growth factor (HGF)-induced cell migration. Required for MMP9 up-regulation via the JNK signaling pathway in colorectal tumor cells. Acts as a mediator of ERBB2-dependent stabilization of microtubules at the cell cortex. It is required for the localization of MACF1 to the cell membrane and this localization of MACF1 is critical for its function in microtubule stabilization. [View more on UniProt]
Protein features
Binary interactions with known binding regions
To display all evidence describing the interaction with a partner, click on the protein name left to the bars.
Network
Isoforms
Disease-causing germline mutations
| Position | Amino acid | Mutation | Disease | Overlap with binding region |
|---|---|---|---|---|
| 171 | Ser | Ile | Familialadenomatouspolyposis1(FAP1) | - |
| 414 | Arg | Cys | Familialadenomatouspolyposis1(FAP1) | - |
| 784 | Ser | Thr | Familialadenomatouspolyposis1(FAP1) | - |
| 817 | Gly | Cys | Gastriccancer(GASC) | - |
| 880 | Ile | Thr | Gastriccancer(GASC) | - |
| 911 | Glu | Gly | Familialadenomatouspolyposis1(FAP1) | - |
| 942 | Asn | Asp | Gastriccancer(GASC) | - |
| 1120 | Gly | Glu | Gastriccancer(GASC) | - |
| 1171 | Arg | His | Gastriccancer(GASC) | - |
| 1176 | Pro | Leu | Familialadenomatouspolyposis1(FAP1) | - |
| 1197 | Phe | Ser | Gastriccancer(GASC) | - |
| 1259 | Ile | Thr | Gastriccancer(GASC) | - |
| 1312 | Gly | Glu | Gastriccancer(GASC) | - |
| 1313 | Thr | Ala | Familialadenomatouspolyposis1(FAP1) | - |
| 1326 | Val | Ala | Gastriccancer(GASC) | - |
| 1348 | Arg | Trp | Familialadenomatouspolyposis1(FAP1) | - |
| 2839 | Leu | Phe | Familialadenomatouspolyposis1(FAP1) | - |
| 722 | Ser | Gly | Familialadenomatouspolyposis1(FAP1) | - |
| 1184 | Ala | Pro | Familialadenomatouspolyposis1(FAP1) | - |
| 1296 | Ala | Val | Medulloblastoma(MDB) | - |
| 1472 | Val | Ile | Medulloblastoma(MDB) | - |
| 1495 | Ser | Gly | Medulloblastoma(MDB) | - |
Linear motifs
| ELM instance | Name | Type | Start | End | Partner |
|---|---|---|---|---|---|
| ELMI001285 | LIG_SxIP_EBH_1 | LIG | 2801 | 2811 | - |
| ELMI003247 | MOD_CDK_SPxK_1 | MOD | 1357 | 1363 | - |
| ELMI003815 | MOD_CK1_1 | MOD | 1507 | 1513 | - |
| ELMI000913 | TRG_NES_CRM1_1 | TRG | 67 | 78 | - |
| ELMI000914 | TRG_NES_CRM1_1 | TRG | 163 | 176 | - |
| ELMI001380 | TRG_NLS_MonoCore_2 | TRG | 2048 | 2053 | - |
| ELMI001379 | TRG_NLS_MonoExtC_3 | TRG | 2048 | 2053 | - |
| ELMI001378 | TRG_NLS_MonoExtN_4 | TRG | 2048 | 2054 | - |
| ELMI002398 | TRG_NLS_MonoExtN_4 | TRG | 2049 | 2054 | - |
Fingerprint
Molecular function
| Term | Name | % | Distance from the top of the tree | Annotated in APC_HUMAN |
|---|---|---|---|---|
| GO:0019900 | kinase binding | 24.0741 | 4 | yes |
| GO:0045296 | cadherin binding | 24.0741 | 4 | no |
| GO:0019901 | protein kinase binding | 23.1481 | 5 | yes |
| GO:0017076 | purine nucleotide binding | 23.1481 | 4 | no |
| GO:0032555 | purine ribonucleotide binding | 22.2222 | 4 | no |
| GO:0035639 | purine ribonucleoside triphosphate binding | 22.2222 | 4 | no |
| GO:0003723 | RNA binding | 21.2963 | 4 | no |
| GO:0015631 | tubulin binding | 18.5185 | 4 | yes |
| GO:0008017 | microtubule binding | 14.8148 | 5 | yes |
| GO:0044389 | ubiquitin-like protein ligase binding | 11.1111 | 4 | yes |
| GO:0031625 | ubiquitin protein ligase binding | 10.1852 | 5 | yes |
| GO:0019887 | protein kinase regulator activity | 7.4074 | 4 | yes |
| GO:0051010 | microtubule plus-end binding | 7.4074 | 6 | yes |
Biological process
| Term | Name | % | Distance from top the of the tree | Annotated in APC_HUMAN |
|---|---|---|---|---|
| GO:0048522 | positive regulation of cellular process | 61.1111 | 4 | yes |
| GO:0060255 | regulation of macromolecule metabolic process | 58.3333 | 4 | yes |
| GO:0051171 | regulation of nitrogen compound metabolic process | 53.7037 | 4 | yes |
| GO:0080090 | regulation of primary metabolic process | 53.7037 | 4 | yes |
| GO:0048523 | negative regulation of cellular process | 50.0000 | 4 | yes |
| GO:0031323 | regulation of cellular metabolic process | 49.0741 | 4 | yes |
| GO:0010646 | regulation of cell communication | 47.2222 | 4 | yes |
| GO:0006996 | organelle organization | 47.2222 | 4 | no |
| GO:0022607 | cellular component assembly | 46.2963 | 4 | yes |
| GO:0051128 | regulation of cellular component organization | 46.2963 | 4 | yes |
| GO:0008104 | protein localization | 45.3704 | 4 | no |
| GO:0009893 | positive regulation of metabolic process | 44.4444 | 4 | yes |
| GO:0010604 | positive regulation of macromolecule metabolic process | 43.5185 | 5 | yes |
| GO:0051246 | regulation of protein metabolic process | 41.6667 | 5 | yes |
| GO:0009966 | regulation of signal transduction | 39.8148 | 4 | yes |
| GO:0051173 | positive regulation of nitrogen compound metabolic process | 38.8889 | 5 | yes |
| GO:0010468 | regulation of gene expression | 37.9630 | 5 | no |
| GO:0007010 | cytoskeleton organization | 33.3333 | 5 | no |
| GO:0051247 | positive regulation of protein metabolic process | 32.4074 | 6 | yes |
| GO:0031325 | positive regulation of cellular metabolic process | 30.5556 | 5 | no |
| GO:0031399 | regulation of protein modification process | 28.7037 | 6 | yes |
| GO:0051130 | positive regulation of cellular component organization | 28.7037 | 5 | yes |
| GO:0023056 | positive regulation of signaling | 28.7037 | 4 | no |
| GO:0071702 | organic substance transport | 28.7037 | 4 | no |
| GO:0010647 | positive regulation of cell communication | 27.7778 | 5 | no |
| GO:0030030 | cell projection organization | 27.7778 | 4 | no |
| GO:0051049 | regulation of transport | 27.7778 | 4 | no |
| GO:0071705 | nitrogen compound transport | 27.7778 | 4 | no |
| GO:0009889 | regulation of biosynthetic process | 27.7778 | 4 | no |
| GO:0031326 | regulation of cellular biosynthetic process | 27.7778 | 5 | no |
| GO:0019219 | regulation of nucleobase-containing compound metabolic process | 26.8519 | 5 | no |
| GO:0010941 | regulation of cell death | 25.9259 | 4 | yes |
| GO:0033043 | regulation of organelle organization | 25.9259 | 5 | yes |
| GO:0044087 | regulation of cellular component biogenesis | 25.9259 | 4 | yes |
| GO:0120036 | plasma membrane bounded cell projection organization | 25.9259 | 5 | no |
| GO:0010556 | regulation of macromolecule biosynthetic process | 25.9259 | 5 | no |
| GO:0048584 | positive regulation of response to stimulus | 25.9259 | 4 | no |
| GO:0009892 | negative regulation of metabolic process | 25.9259 | 4 | yes |
| GO:0019220 | regulation of phosphate metabolic process | 25.0000 | 6 | yes |
| GO:0042127 | regulation of cell population proliferation | 25.0000 | 4 | yes |
| GO:0051174 | regulation of phosphorus metabolic process | 25.0000 | 5 | yes |
| GO:0060341 | regulation of cellular localization | 25.0000 | 4 | yes |
| GO:0010605 | negative regulation of macromolecule metabolic process | 24.0741 | 5 | yes |
| GO:0051252 | regulation of RNA metabolic process | 24.0741 | 5 | no |
| GO:0032880 | regulation of protein localization | 23.1481 | 5 | yes |
| GO:0045595 | regulation of cell differentiation | 23.1481 | 4 | yes |
| GO:0015031 | protein transport | 23.1481 | 4 | no |
| GO:0009967 | positive regulation of signal transduction | 23.1481 | 5 | no |
| GO:0031344 | regulation of cell projection organization | 22.2222 | 5 | yes |
| GO:0051493 | regulation of cytoskeleton organization | 22.2222 | 6 | yes |
| GO:0031401 | positive regulation of protein modification process | 22.2222 | 7 | no |
| GO:0006355 | regulation of DNA-templated transcription | 22.2222 | 6 | no |
| GO:0051094 | positive regulation of developmental process | 22.2222 | 4 | no |
| GO:1903506 | regulation of nucleic acid-templated transcription | 22.2222 | 7 | no |
| GO:2001141 | regulation of RNA biosynthetic process | 22.2222 | 6 | no |
| GO:0016192 | vesicle-mediated transport | 22.2222 | 4 | no |
| GO:0042325 | regulation of phosphorylation | 21.2963 | 7 | yes |
| GO:0042981 | regulation of apoptotic process | 21.2963 | 6 | yes |
| GO:0043067 | regulation of programmed cell death | 21.2963 | 5 | yes |
| GO:0043933 | protein-containing complex organization | 21.2963 | 4 | yes |
| GO:0120035 | regulation of plasma membrane bounded cell projection organization | 21.2963 | 6 | yes |
| GO:0036211 | protein modification process | 21.2963 | 4 | no |
| GO:0043412 | macromolecule modification | 21.2963 | 4 | no |
| GO:1902531 | regulation of intracellular signal transduction | 21.2963 | 5 | no |
| GO:0009894 | regulation of catabolic process | 20.3704 | 4 | yes |
| GO:0001932 | regulation of protein phosphorylation | 20.3704 | 7 | yes |
| GO:0031324 | negative regulation of cellular metabolic process | 19.4444 | 5 | yes |
| GO:0048585 | negative regulation of response to stimulus | 19.4444 | 4 | yes |
| GO:0051172 | negative regulation of nitrogen compound metabolic process | 19.4444 | 5 | yes |
| GO:0065003 | protein-containing complex assembly | 19.4444 | 5 | yes |
| GO:0010648 | negative regulation of cell communication | 18.5185 | 5 | yes |
| GO:0023057 | negative regulation of signaling | 18.5185 | 4 | yes |
| GO:0031346 | positive regulation of cell projection organization | 17.5926 | 6 | yes |
| GO:0034330 | cell junction organization | 17.5926 | 4 | yes |
| GO:0051129 | negative regulation of cellular component organization | 17.5926 | 5 | yes |
| GO:1903829 | positive regulation of protein localization | 17.5926 | 5 | yes |
| GO:0009968 | negative regulation of signal transduction | 16.6667 | 5 | yes |
| GO:0042176 | regulation of protein catabolic process | 16.6667 | 5 | yes |
| GO:0051338 | regulation of transferase activity | 16.6667 | 4 | yes |
| GO:1902903 | regulation of supramolecular fiber organization | 16.6667 | 5 | yes |
| GO:0008285 | negative regulation of cell population proliferation | 16.6667 | 5 | yes |
| GO:0044089 | positive regulation of cellular component biogenesis | 15.7407 | 5 | yes |
| GO:2000145 | regulation of cell motility | 15.7407 | 4 | yes |
| GO:0016055 | Wnt signaling pathway | 14.8148 | 5 | yes |
| GO:0030334 | regulation of cell migration | 14.8148 | 5 | yes |
| GO:0043549 | regulation of kinase activity | 14.8148 | 5 | yes |
| GO:0051240 | positive regulation of multicellular organismal process | 14.8148 | 4 | yes |
| GO:0051248 | negative regulation of protein metabolic process | 14.8148 | 6 | yes |
| GO:1905114 | cell surface receptor signaling pathway involved in cell-cell signaling | 14.8148 | 4 | yes |
| GO:0045859 | regulation of protein kinase activity | 13.8889 | 6 | yes |
| GO:0032886 | regulation of microtubule-based process | 12.9630 | 4 | yes |
| GO:0051726 | regulation of cell cycle | 12.9630 | 4 | yes |
| GO:0034329 | cell junction assembly | 12.0370 | 5 | yes |
| GO:0009896 | positive regulation of catabolic process | 11.1111 | 5 | yes |
| GO:0045216 | cell-cell junction organization | 11.1111 | 5 | yes |
| GO:0070507 | regulation of microtubule cytoskeleton organization | 11.1111 | 5 | yes |
| GO:0030111 | regulation of Wnt signaling pathway | 10.1852 | 5 | yes |
| GO:0045732 | positive regulation of protein catabolic process | 10.1852 | 6 | yes |
| GO:0010639 | negative regulation of organelle organization | 9.2593 | 6 | yes |
| GO:0010942 | positive regulation of cell death | 9.2593 | 5 | yes |
| GO:0030335 | positive regulation of cell migration | 9.2593 | 6 | yes |
| GO:0031400 | negative regulation of protein modification process | 9.2593 | 7 | yes |
| GO:0040017 | positive regulation of locomotion | 9.2593 | 4 | yes |
| GO:0051494 | negative regulation of cytoskeleton organization | 9.2593 | 7 | yes |
| GO:1902904 | negative regulation of supramolecular fiber organization | 9.2593 | 6 | yes |
| GO:2000147 | positive regulation of cell motility | 9.2593 | 5 | yes |
| GO:0031110 | regulation of microtubule polymerization or depolymerization | 8.3333 | 6 | yes |
| GO:0060491 | regulation of cell projection assembly | 8.3333 | 5 | yes |
| GO:0060828 | regulation of canonical Wnt signaling pathway | 8.3333 | 6 | yes |
| GO:0120032 | regulation of plasma membrane bounded cell projection assembly | 8.3333 | 6 | yes |
| GO:0120034 | positive regulation of plasma membrane bounded cell projection assembly | 8.3333 | 6 | yes |
| GO:0010563 | negative regulation of phosphorus metabolic process | 7.4074 | 6 | yes |
| GO:0010564 | regulation of cell cycle process | 7.4074 | 5 | yes |
| GO:0043065 | positive regulation of apoptotic process | 7.4074 | 7 | yes |
| GO:0043068 | positive regulation of programmed cell death | 7.4074 | 6 | yes |
| GO:0043242 | negative regulation of protein-containing complex disassembly | 7.4074 | 6 | yes |
| GO:0043244 | regulation of protein-containing complex disassembly | 7.4074 | 5 | yes |
| GO:0045936 | negative regulation of phosphate metabolic process | 7.4074 | 7 | yes |
| GO:1901879 | regulation of protein depolymerization | 7.4074 | 6 | yes |
| GO:1901880 | negative regulation of protein depolymerization | 7.4074 | 7 | yes |
| GO:0006974 | cellular response to DNA damage stimulus | 7.4074 | 4 | yes |
| GO:0007043 | cell-cell junction assembly | 7.4074 | 6 | yes |
| GO:0007167 | enzyme-linked receptor protein signaling pathway | 7.4074 | 4 | yes |
| GO:0007169 | transmembrane receptor protein tyrosine kinase signaling pathway | 7.4074 | 5 | yes |
| GO:0043086 | negative regulation of catalytic activity | 6.4815 | 4 | yes |
| GO:0071900 | regulation of protein serine/threonine kinase activity | 6.4815 | 7 | yes |
| GO:0007346 | regulation of mitotic cell cycle | 6.4815 | 5 | yes |
| GO:0007399 | nervous system development | 6.4815 | 4 | yes |
| GO:0051348 | negative regulation of transferase activity | 5.5556 | 5 | yes |
| GO:0061640 | cytoskeleton-dependent cytokinesis | 5.5556 | 4 | yes |
| GO:0030178 | negative regulation of Wnt signaling pathway | 4.6296 | 6 | yes |
| GO:0033673 | negative regulation of kinase activity | 4.6296 | 6 | yes |
| GO:0042326 | negative regulation of phosphorylation | 4.6296 | 8 | yes |
| GO:0045786 | negative regulation of cell cycle | 4.6296 | 5 | yes |
| GO:0045930 | negative regulation of mitotic cell cycle | 4.6296 | 6 | yes |
| GO:0090090 | negative regulation of canonical Wnt signaling pathway | 4.6296 | 7 | yes |
| GO:0000281 | mitotic cytokinesis | 4.6296 | 4 | yes |
| GO:0001933 | negative regulation of protein phosphorylation | 4.6296 | 8 | yes |
| GO:0006469 | negative regulation of protein kinase activity | 4.6296 | 7 | yes |
| GO:0031111 | negative regulation of microtubule polymerization or depolymerization | 3.7037 | 7 | yes |
| GO:0070830 | bicellular tight junction assembly | 3.7037 | 8 | yes |
| GO:0120192 | tight junction assembly | 3.7037 | 7 | yes |
| GO:0120193 | tight junction organization | 3.7037 | 6 | yes |
| GO:1904029 | regulation of cyclin-dependent protein kinase activity | 3.7037 | 5 | yes |
| GO:0000079 | regulation of cyclin-dependent protein serine/threonine kinase activity | 3.7037 | 6 | yes |
| GO:0008286 | insulin receptor signaling pathway | 3.7037 | 6 | yes |
| GO:0010948 | negative regulation of cell cycle process | 2.7778 | 6 | yes |
| GO:0031114 | regulation of microtubule depolymerization | 2.7778 | 6 | yes |
| GO:0031272 | regulation of pseudopodium assembly | 2.7778 | 7 | yes |
| GO:0031274 | positive regulation of pseudopodium assembly | 2.7778 | 7 | yes |
| GO:0033044 | regulation of chromosome organization | 2.7778 | 6 | yes |
| GO:0051783 | regulation of nuclear division | 2.7778 | 6 | yes |
| GO:0051983 | regulation of chromosome segregation | 2.7778 | 4 | yes |
| GO:0051988 | regulation of attachment of spindle microtubules to kinetochore | 2.7778 | 6 | yes |
| GO:0071901 | negative regulation of protein serine/threonine kinase activity | 2.7778 | 8 | yes |
| GO:0120162 | positive regulation of cold-induced thermogenesis | 2.7778 | 4 | yes |
| GO:1901987 | regulation of cell cycle phase transition | 2.7778 | 6 | yes |
| GO:1901988 | negative regulation of cell cycle phase transition | 2.7778 | 7 | yes |
| GO:1901990 | regulation of mitotic cell cycle phase transition | 2.7778 | 6 | yes |
| GO:1901991 | negative regulation of mitotic cell cycle phase transition | 2.7778 | 7 | yes |
| GO:1902806 | regulation of cell cycle G1/S phase transition | 2.7778 | 7 | yes |
| GO:1902807 | negative regulation of cell cycle G1/S phase transition | 2.7778 | 8 | yes |
| GO:1904779 | regulation of protein localization to centrosome | 2.7778 | 6 | yes |
| GO:1904781 | positive regulation of protein localization to centrosome | 2.7778 | 6 | yes |
| GO:1905818 | regulation of chromosome separation | 2.7778 | 5 | yes |
| GO:2000045 | regulation of G1/S transition of mitotic cell cycle | 2.7778 | 7 | yes |
| GO:2000134 | negative regulation of G1/S transition of mitotic cell cycle | 2.7778 | 8 | yes |
| GO:0007026 | negative regulation of microtubule depolymerization | 2.7778 | 7 | yes |
| GO:0007088 | regulation of mitotic nuclear division | 2.7778 | 6 | yes |
| GO:0010965 | regulation of mitotic sister chromatid separation | 1.8519 | 6 | yes |
| GO:0030071 | regulation of mitotic metaphase/anaphase transition | 1.8519 | 7 | yes |
| GO:0031577 | spindle checkpoint signaling | 1.8519 | 5 | yes |
| GO:0033045 | regulation of sister chromatid segregation | 1.8519 | 5 | yes |
| GO:0033046 | negative regulation of sister chromatid segregation | 1.8519 | 6 | yes |
| GO:0033047 | regulation of mitotic sister chromatid segregation | 1.8519 | 6 | yes |
| GO:0033048 | negative regulation of mitotic sister chromatid segregation | 1.8519 | 7 | yes |
| GO:0045736 | negative regulation of cyclin-dependent protein serine/threonine kinase activity | 1.8519 | 6 | yes |
| GO:0045839 | negative regulation of mitotic nuclear division | 1.8519 | 7 | yes |
| GO:0045841 | negative regulation of mitotic metaphase/anaphase transition | 1.8519 | 8 | yes |
| GO:0051784 | negative regulation of nuclear division | 1.8519 | 7 | yes |
| GO:0051985 | negative regulation of chromosome segregation | 1.8519 | 5 | yes |
| GO:0071173 | spindle assembly checkpoint signaling | 1.8519 | 6 | yes |
| GO:0071174 | mitotic spindle checkpoint signaling | 1.8519 | 5 | yes |
| GO:1902099 | regulation of metaphase/anaphase transition of cell cycle | 1.8519 | 6 | yes |
| GO:1902100 | negative regulation of metaphase/anaphase transition of cell cycle | 1.8519 | 7 | yes |
| GO:1904030 | negative regulation of cyclin-dependent protein kinase activity | 1.8519 | 6 | yes |
| GO:1905819 | negative regulation of chromosome separation | 1.8519 | 6 | yes |
| GO:2000816 | negative regulation of mitotic sister chromatid separation | 1.8519 | 7 | yes |
| GO:2001251 | negative regulation of chromosome organization | 1.8519 | 7 | yes |
| GO:0000075 | cell cycle checkpoint signaling | 1.8519 | 4 | yes |
| GO:0007093 | mitotic cell cycle checkpoint signaling | 1.8519 | 4 | yes |
| GO:0007094 | mitotic spindle assembly checkpoint signaling | 1.8519 | 6 | yes |
Disease
| Term | Name | % | Distance from top the of the tree | Annotated in APC_HUMAN |
|---|---|---|---|---|
| DOID:0050686 | organ system cancer | 2.7778 | 3 | yes |
| DOID:0050424 | familial adenomatous polyposis | 1.8519 | 4 | yes |
| DOID:0050902 | medulloblastoma | 1.8519 | 8 | yes |
| DOID:0080409 | familial adenomatous polyposis 1 | 1.8519 | 5 | yes |
| DOID:10534 | stomach cancer | 1.8519 | 5 | yes |
| DOID:1319 | brain cancer | 1.8519 | 6 | yes |
| DOID:3093 | nervous system cancer | 1.8519 | 4 | yes |
| DOID:3119 | gastrointestinal system cancer | 1.8519 | 4 | yes |
| DOID:3620 | central nervous system cancer | 1.8519 | 5 | yes |
| DOID:4706 | infratentorial cancer | 1.8519 | 7 | yes |
| DOID:5295 | intestinal disease | 1.8519 | 3 | yes |
All partners
| Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
|---|---|---|---|---|
| RBP2_HUMAN | [view interactions] | Low throughput | no | yes |
| ASAP1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| NMDE2_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| PTN13_HUMAN | [view interactions] | Low throughput | no | yes |
| ARHG4_HUMAN | [view interactions] | Low throughput | no | yes |
| SIAH1_HUMAN | [view interactions] | Low throughput | no | yes |
| CSK21_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| BUB1_HUMAN | [view interactions] | Low throughput | no | no |
| STRN3_HUMAN | [view interactions] | Low throughput | no | yes |
| MARE2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| DLG3_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| MUC1_HUMAN | [view interactions] | Low throughput | no | no |
| XPO1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| APC_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| AP2A_HUMAN | [view interactions] | Low throughput | no | no |
| CSK2B_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| DLGP1_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| MD2L1_HUMAN | [view interactions] | Low throughput | no | no |
| BUB3_HUMAN | [view interactions] | Low throughput | no | yes |
| AXIN2_HUMAN | [view interactions] | Low throughput | no | yes |
| ZRAN1_HUMAN | [view interactions] | Low throughput | no | yes |
| OTU7B_HUMAN | [view interactions] | Low throughput | no | yes |
| PCNA_HUMAN | [view interactions] | Low throughput | no | no |
| RFA2_HUMAN | [view interactions] | Low throughput | no | yes |
| STRN_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| STRN4_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| UBR5_HUMAN | [view interactions] | Low throughput | no | no |
| UBP7_HUMAN | [view interactions] | Low throughput | no | yes |
| MKRN1_HUMAN | [view interactions] | Low throughput | no | no |
| PRC1_HUMAN | [view interactions] | Low throughput | no | yes |
| RNF43_HUMAN | [view interactions] | Low throughput | no | yes |
| AMER3_HUMAN | [view interactions] | Low throughput | no | no |
| SPT13_HUMAN | [view interactions] | Low throughput | no | yes |
| CDC42_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| AXIN1_HUMAN | [view interactions] | Low throughput | no | yes |
| FBW1A_HUMAN | [view interactions] | Low throughput | no | yes |
| PAXI_HUMAN | [view interactions] | Low throughput | no | yes |
| KC1E_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| AMER1_HUMAN | [view interactions] | Low throughput | no | yes |
| AMER2_HUMAN | [view interactions] | Low throughput | no | yes |
| GSK3B_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| PLAK_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| DVL2_HUMAN | [view interactions] | Low throughput | no | yes |
| CTBP1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| CRBN_HUMAN | [view interactions] | Low throughput | no | yes |
| CTNB1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| CTNA1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| KCTD1_HUMAN | [view interactions] | Low throughput | no | no |
| MARE1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| CNBP1_HUMAN | [view interactions] | Low throughput | no | no |
| TBA4A_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| HTRA2_HUMAN | [view interactions] | Low throughput | no | yes |
| RAC1_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| ASAP2_HUMAN | [view interactions] | Low throughput | no | yes |
| SCRIB_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| BUB1B_HUMAN | [view interactions] | Low throughput | no | no |
| KC1A_HUMAN | [view interactions] | Low throughput | no | yes |
| 2A5A_HUMAN | [view interactions] | Low throughput | no | yes |
| DVLP1_HUMAN | [view interactions] | Low throughput | no | no |
| DLG4_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| LRP8_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| EPCR_HUMAN | [view interactions] | Low throughput | no | yes |
| KIF3B_HUMAN | [view interactions] | Low throughput | no | no |
| NMDE1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| KIFA3_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| KHDR1_HUMAN | [view interactions] | Low throughput | no | yes |
| DLG1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| COG5_HUMAN | [view interactions] | High throughput | no | yes |
| CBP_HUMAN | [view interactions] | High throughput | no | yes |
| SMC3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DYST_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GOGA2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HGS_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AGFG1_HUMAN | [view interactions] | High throughput | no | yes |
| FLNA_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| FHOD1_HUMAN | [view interactions] | High throughput | no | no |
| EPAS1_HUMAN | [view interactions] | High throughput | no | no |
| ERBIN_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FBX30_HUMAN | [view interactions] | High throughput | no | yes |
| BIP_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| K1C14_HUMAN | [view interactions] | High throughput | no | no |
| K1C13_HUMAN | [view interactions] | High throughput | no | no |
| KINH_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ING5_HUMAN | [view interactions] | High throughput | no | yes |
| K1C19_HUMAN | [view interactions] | High throughput | no | no |
| AGRL1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| LAMA4_HUMAN | [view interactions] | High throughput | no | no |
| LAMA3_HUMAN | [view interactions] | High throughput | no | no |
| K1C15_HUMAN | [view interactions] | High throughput | no | no |
| K2C5_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| K1C23_HUMAN | [view interactions] | High throughput | no | no |
| NAV3_HUMAN | [view interactions] | High throughput | no | yes |
| NAV2_HUMAN | [view interactions] | High throughput | no | yes |
| NAV1_HUMAN | [view interactions] | High throughput | no | yes |
| NCKP5_HUMAN | [view interactions] | High throughput | no | no |
| MYH11_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| MYH10_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MBD5_HUMAN | [view interactions] | High throughput | no | no |
| MACF1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GANP_HUMAN | [view interactions] | High throughput | no | yes |
| MYO6_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| NU153_HUMAN | [view interactions] | High throughput | no | yes |
| NU214_HUMAN | [view interactions] | High throughput | no | no |
| NUP54_HUMAN | [view interactions] | High throughput | no | yes |
| NUP98_HUMAN | [view interactions] | High throughput | no | no |
| NUP58_HUMAN | [view interactions] | High throughput | no | yes |
| NUP42_HUMAN | [view interactions] | High throughput | no | no |
| NEBU_HUMAN | [view interactions] | High throughput | no | no |
| RANB9_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| P121A_HUMAN | [view interactions] | High throughput | no | yes |
| ASPP1_HUMAN | [view interactions] | High throughput | no | yes |
| CYH2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PSMD1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RBM4B_HUMAN | [view interactions] | High throughput | no | yes |
| SC31A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RS27_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| SETB1_HUMAN | [view interactions] | High throughput | no | yes |
| SYNE1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SPTN2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| EXPH5_HUMAN | [view interactions] | High throughput | no | no |
| SPTB2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TAF1_HUMAN | [view interactions] | High throughput | no | yes |
| RO52_HUMAN | [view interactions] | High throughput | no | yes |
| TPR_HUMAN | [view interactions] | High throughput | no | yes |
| ZN106_HUMAN | [view interactions] | High throughput | no | no |
| NOSTN_HUMAN | [view interactions] | High throughput | no | yes |
| CYTSA_HUMAN | [view interactions] | High throughput | no | yes |
| PNISR_HUMAN | [view interactions] | High throughput | no | yes |
| K1328_HUMAN | [view interactions] | High throughput | no | yes |
| F214A_HUMAN | [view interactions] | High throughput | no | yes |
| P121C_HUMAN | [view interactions] | High throughput | no | yes |
| NCK5L_HUMAN | [view interactions] | High throughput | no | yes |
| GGYF2_HUMAN | [view interactions] | High throughput | no | yes |
| CO4A_HUMAN | [view interactions] | High throughput | no | no |
| 1433S_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CKAP5_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ESR1_HUMAN | [view interactions] | High throughput | no | no |
| FAK1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ANR28_HUMAN | [view interactions] | High throughput | no | no |
| LATS2_HUMAN | [view interactions] | High throughput | no | yes |
| FTM_HUMAN | [view interactions] | High throughput | no | yes |
| CE128_HUMAN | [view interactions] | High throughput | no | yes |
| SAS6_HUMAN | [view interactions] | High throughput | no | no |
| TOM20_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FGFR4_HUMAN | [view interactions] | High throughput | no | no |
| FHI2A_HUMAN | [view interactions] | High throughput | no | yes |
| HOOK2_HUMAN | [view interactions] | High throughput | no | yes |
| NU4M_HUMAN | [view interactions] | High throughput | no | yes |
| HNRPM_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| U520_HUMAN | [view interactions] | High throughput | no | yes |
| UBC_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CSN5_HUMAN | [view interactions] | High throughput | no | yes |
| TNKS1_HUMAN | [view interactions] | High throughput | no | yes |
| HECD1_HUMAN | [view interactions] | High throughput | no | yes |
| RN146_HUMAN | [view interactions] | High throughput | no | yes |
| CFTR_HUMAN | [view interactions] | High throughput | no | no |
| CP250_HUMAN | [view interactions] | High throughput | no | no |
| AP2M1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| EF1D_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MARK2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PKP2_HUMAN | [view interactions] | High throughput | no | yes |
| MBD4_HUMAN | [view interactions] | High throughput | no | yes |
| AKP13_HUMAN | [view interactions] | High throughput | no | yes |
| RFOX2_HUMAN | [view interactions] | High throughput | no | yes |
| SENP1_HUMAN | [view interactions] | High throughput | no | no |
| BBX_HUMAN | [view interactions] | High throughput | no | no |
| TRAF1_HUMAN | [view interactions] | High throughput | no | no |
| SYNCI_HUMAN | [view interactions] | High throughput | no | no |
| ACADV_HUMAN | [view interactions] | High throughput | no | yes |
| IQCN_HUMAN | [view interactions] | High throughput | no | no |
| ZN785_HUMAN | [view interactions] | High throughput | no | no |
| KC1D_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| UBP30_HUMAN | [view interactions] | High throughput | no | yes |
| RN114_HUMAN | [view interactions] | High throughput | no | no |
| ZFP91_HUMAN | [view interactions] | High throughput | no | yes |
| TRI32_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HEY1_HUMAN | [view interactions] | High throughput | no | yes |
| RNF31_HUMAN | [view interactions] | High throughput | no | yes |
| SMU1_HUMAN | [view interactions] | High throughput | no | yes |
| VIR_HUMAN | [view interactions] | High throughput | no | yes |
| PP1G_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KIF14_HUMAN | [view interactions] | High throughput | no | no |
| KIF23_HUMAN | [view interactions] | High throughput | no | yes |
| DDX58_HUMAN | [view interactions] | High throughput | no | yes |
| KRT38_HUMAN | [view interactions] | High throughput | no | no |
| TX1B3_HUMAN | [view interactions] | High throughput | no | no |
| SULF2_HUMAN | [view interactions] | High throughput | no | yes |
| SLU7_HUMAN | [view interactions] | High throughput | no | yes |
| ZBT44_HUMAN | [view interactions] | High throughput | no | yes |
| C2C4B_HUMAN | [view interactions] | High throughput | no | no |
| NET5_HUMAN | [view interactions] | High throughput | no | no |
| RN145_HUMAN | [view interactions] | High throughput | no | yes |
| COQ3_HUMAN | [view interactions] | High throughput | no | no |
| FHL2_HUMAN | [view interactions] | High throughput | no | yes |
| BL1S6_HUMAN | [view interactions] | High throughput | no | yes |
| 1433B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DVL1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| S35G1_HUMAN | [view interactions] | High throughput | no | no |
| CCD71_HUMAN | [view interactions] | High throughput | no | no |
| EMIL3_HUMAN | [view interactions] | High throughput | no | yes |
| SPB1_HUMAN | [view interactions] | High throughput | no | yes |
| EGLN3_HUMAN | [view interactions] | High throughput | no | no |
| ENTP1_HUMAN | [view interactions] | High throughput | no | yes |
| MAP10_HUMAN | [view interactions] | High throughput | no | no |
| KRT37_HUMAN | [view interactions] | High throughput | no | no |
| WIZ_HUMAN | [view interactions] | High throughput | no | yes |
| LIN7B_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RHG21_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RUVB2_HUMAN | [view interactions] | High throughput | no | yes |
| YM012_HUMAN | [view interactions] | High throughput | no | no |
| SLN11_HUMAN | [view interactions] | High throughput | no | yes |
| FA83B_HUMAN | [view interactions] | High throughput | no | no |
| SIR6_HUMAN | [view interactions] | High throughput | no | yes |
| RBCC1_HUMAN | [view interactions] | High throughput | no | no |
| TELO2_HUMAN | [view interactions] | High throughput | no | yes |
| RM18_HUMAN | [view interactions] | High throughput | no | yes |
| PLK4_HUMAN | [view interactions] | High throughput | no | yes |
| TRAP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MD1L1_HUMAN | [view interactions] | High throughput | no | yes |
| COPZ1_HUMAN | [view interactions] | High throughput | no | no |
| K1C17_HUMAN | [view interactions] | High throughput | no | no |
| DDX21_HUMAN | [view interactions] | High throughput | no | yes |
| TBB4B_HUMAN | [view interactions] | High throughput | no | yes |
| SAV1_HUMAN | [view interactions] | High throughput | no | yes |
| 1433E_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FLOT2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TNKS2_HUMAN | [view interactions] | High throughput | no | no |
| CDK9_HUMAN | [view interactions] | High throughput | no | yes |
| FBW1B_HUMAN | [view interactions] | High throughput | no | yes |
| VHL_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SYNPO_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| SNF5_HUMAN | [view interactions] | High throughput | no | yes |
| ALDH2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| NHSL1_HUMAN | [view interactions] | High throughput | no | yes |
| DCC_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KIF7_HUMAN | [view interactions] | High throughput | no | yes |
| CDK4_HUMAN | [view interactions] | High throughput | no | no |
| LZTS2_HUMAN | [view interactions] | High throughput | no | no |
| I22R1_HUMAN | [view interactions] | High throughput | no | no |
| LIN7C_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| IL22_HUMAN | [view interactions] | High throughput | no | no |
| ZN408_HUMAN | [view interactions] | High throughput | no | no |
| PK3CA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CTNA3_HUMAN | [view interactions] | High throughput | no | no |
| CCDC6_HUMAN | [view interactions] | High throughput | no | yes |
| 1433T_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NOLC1_HUMAN | [view interactions] | High throughput | no | yes |
| SC23A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DDB1_HUMAN | [view interactions] | High throughput | no | yes |
| NU107_HUMAN | [view interactions] | High throughput | no | no |
| MCM5_HUMAN | [view interactions] | High throughput | no | no |
| HOOK3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CAZA2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NIN_HUMAN | [view interactions] | High throughput | no | no |
| TIF1B_HUMAN | [view interactions] | High throughput | no | yes |
| F120C_HUMAN | [view interactions] | High throughput | no | yes |
| 1433Z_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PATL1_HUMAN | [view interactions] | High throughput | no | yes |
| SMAG2_HUMAN | [view interactions] | High throughput | no | yes |
| CSKP_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CEP85_HUMAN | [view interactions] | High throughput | no | no |
| PLK1_HUMAN | [view interactions] | High throughput | no | yes |
| CNOT9_HUMAN | [view interactions] | High throughput | no | yes |
| MKRN2_HUMAN | [view interactions] | High throughput | no | yes |
| ARP3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| IGHA1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AMOT_HUMAN | [view interactions] | High throughput | no | no |
| K2C1_HUMAN | [view interactions] | High throughput | no | no |
| ANC2_HUMAN | [view interactions] | High throughput | no | no |
| K1C9_HUMAN | [view interactions] | High throughput | no | no |
| B3GA1_HUMAN | [view interactions] | High throughput | no | yes |
| CAV1_HUMAN | [view interactions] | High throughput | no | no |
| PTBP3_HUMAN | [view interactions] | High throughput | no | no |
| CP135_HUMAN | [view interactions] | High throughput | no | no |
| FMR1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DCTN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MYCB2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| E41LA_HUMAN | [view interactions] | High throughput | no | yes |
| TNIK_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| EZRI_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| HDAC4_HUMAN | [view interactions] | High throughput | no | yes |
| FLOT1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CXA1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KIF3A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GOGA1_HUMAN | [view interactions] | High throughput | no | yes |
| KDM1A_HUMAN | [view interactions] | High throughput | no | yes |
| K1C18_HUMAN | [view interactions] | High throughput | no | no |
| K2C8_HUMAN | [view interactions] | High throughput | no | no |
| LATS1_HUMAN | [view interactions] | High throughput | no | yes |
| FA20C_HUMAN | [view interactions] | High throughput | no | no |
| LYN_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| AN32B_HUMAN | [view interactions] | High throughput | no | yes |
| MARE3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| BAAT_HUMAN | [view interactions] | High throughput | no | no |
| AFAD_HUMAN | [view interactions] | High throughput | no | yes |
| TSTD2_HUMAN | [view interactions] | High throughput | no | yes |
| OCLN_HUMAN | [view interactions] | High throughput | no | no |
| FANCC_HUMAN | [view interactions] | High throughput | no | yes |
| PARD3_HUMAN | [view interactions] | High throughput | no | yes |
| CATL2_HUMAN | [view interactions] | High throughput | no | yes |
| PROF1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MP2K1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RAB35_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SIAS_HUMAN | [view interactions] | High throughput | no | yes |
| SEP10_HUMAN | [view interactions] | High throughput | no | yes |
| F16P1_HUMAN | [view interactions] | High throughput | no | no |
| STIL_HUMAN | [view interactions] | High throughput | no | no |
| SMAD1_HUMAN | [view interactions] | High throughput | no | yes |
| STX4_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RASA1_HUMAN | [view interactions] | High throughput | no | yes |
| SYNE3_HUMAN | [view interactions] | High throughput | no | no |
| CANB2_HUMAN | [view interactions] | High throughput | no | no |
| ZO2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| TEFF1_HUMAN | [view interactions] | High throughput | no | no |
| TRI36_HUMAN | [view interactions] | High throughput | no | no |
| TGFB1_HUMAN | [view interactions] | High throughput | no | no |
| ZFPL1_HUMAN | [view interactions] | High throughput | no | yes |
| TMOD1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ZYX_HUMAN | [view interactions] | High throughput | no | no |
| ZN510_HUMAN | [view interactions] | High throughput | no | yes |
| TAXB1_HUMAN | [view interactions] | High throughput | no | yes |
| AGR3_HUMAN | [view interactions] | High throughput | no | no |
| CASC3_HUMAN | [view interactions] | High throughput | no | yes |
| CCL5_HUMAN | [view interactions] | High throughput | no | no |
| CP17A_HUMAN | [view interactions] | High throughput | no | no |
| DIRA3_HUMAN | [view interactions] | High throughput | no | yes |
| DKK3_HUMAN | [view interactions] | High throughput | no | yes |
| HXC6_HUMAN | [view interactions] | High throughput | no | no |
| ARY2_HUMAN | [view interactions] | High throughput | no | no |
| IL24_HUMAN | [view interactions] | High throughput | no | no |
| PDLI2_HUMAN | [view interactions] | High throughput | no | no |
| ST14_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TFF1_HUMAN | [view interactions] | High throughput | no | no |
| TRI25_HUMAN | [view interactions] | High throughput | no | yes |
| ANR17_HUMAN | [view interactions] | High throughput | no | yes |
| ANXA7_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AP2B1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ACTN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CGNL1_HUMAN | [view interactions] | High throughput | no | no |
| COG4_HUMAN | [view interactions] | High throughput | no | no |
| FZD2_HUMAN | [view interactions] | Computational | no | no |
| APCL_HUMAN | [view entry] [view interactions] | Computational | yes | no |
| CADH1_HUMAN | [view entry] [view interactions] | Computational | yes | no |
| WNT1_HUMAN | [view interactions] | Computational | no | no |
| CUL1_HUMAN | [view interactions] | Computational | no | yes |
| LEF1_HUMAN | [view interactions] | Computational | no | no |
| TLE1_HUMAN | [view interactions] | Computational | no | yes |
| PA21B_HUMAN | [view interactions] | Computational | no | no |
| TCF7_HUMAN | [view interactions] | Computational | no | no |
| TLE4_HUMAN | [view interactions] | Computational | no | no |
| DVL3_HUMAN | [view interactions] | Computational | no | yes |
| FZD1_HUMAN | [view interactions] | Computational | no | yes |
| GSK3A_HUMAN | [view interactions] | Computational | no | yes |
| SKP1_HUMAN | [view interactions] | Computational | no | yes |
| CYBP_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| LRP6_HUMAN | [view interactions] | Computational | no | yes |
| FRAT1_HUMAN | [view interactions] | Computational | no | yes |
| WNT8B_HUMAN | [view interactions] | Computational | no | no |
| TLE3_HUMAN | [view interactions] | Computational | no | yes |
| WNT3A_HUMAN | [view entry] [view interactions] | Computational | yes | no |
| TFDP3_HUMAN | [view interactions] | Computational | no | no |
| CASP3_HUMAN | [view interactions] | Computational | no | yes |
| HDAC1_HUMAN | [view interactions] | Computational | no | no |
| WNT3_HUMAN | [view interactions] | Computational | no | no |
| FZD5_HUMAN | [view interactions] | Computational | no | yes |
| TF7L2_HUMAN | [view interactions] | Computational | no | yes |
| FRAT2_HUMAN | [view interactions] | Computational | no | no |
| TBL1R_HUMAN | [view interactions] | Computational | no | yes |
| 2A5D_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| LRP5_HUMAN | [view interactions] | Computational | no | yes |
| SMAD4_HUMAN | [view interactions] | Computational | no | yes |