MARK2_HUMAN
Evidence for PS localization
Functions
Serine/threonine-protein kinase (PubMed). Involved in cell polarity and microtubule dynamics regulation. Phosphorylates CRTC2/TORC2, DCX, HDAC7, KIF13B, MAP2, MAP4 and RAB11FIP2. Phosphorylates the microtubule-associated protein MAPT/TAU (PubMed). Plays a key role in cell polarity by phosphorylating the microtubule-associated proteins MAP2, MAP4 and MAPT/TAU at KXGS motifs, causing detachment from microtubules, and their disassembly. Regulates epithelial cell polarity by phosphorylating RAB11FIP2. Involved in the regulation of neuronal migration through its dual activities in regulating cellular polarity and microtubule dynamics, possibly by phosphorylating and regulating DCX. Regulates axogenesis by phosphorylating KIF13B, promoting interaction between KIF13B and 14-3-3 and inhibiting microtubule-dependent accumulation of KIF13B. Also required for neurite outgrowth and establishment of neuronal polarity. Regulates localization and activity of some histone deacetylases by mediating phosphorylation of HDAC7, promoting subsequent interaction between HDAC7 and 14-3-3 and export from the nucleus. Also acts as a positive regulator of the Wnt signaling pathway, probably by mediating phosphorylation of dishevelled proteins (DVL1, DVL2 and/or DVL3). Modulates the developmental decision to build a columnar versus a hepatic epithelial cell apparently by promoting a switch from a direct to a transcytotic mode of apical protein delivery. Essential for the asymmetric development of membrane domains of polarized epithelial cells. [View more on UniProt]
Protein features
Binary interactions with known binding regions
To display all evidence describing the interaction with a partner, click on the protein name left to the bars.
Network
Isoforms
Disease-causing germline mutations
No data found.
Linear motifs
No annotated instance was found. To search for linear motifs, use the ELM prediction server.
Fingerprint
Molecular function
| Term | Name | % | Distance from the top of the tree | Annotated in MARK2_HUMAN |
|---|---|---|---|---|
| GO:0043168 | anion binding | 38.6792 | 4 | yes |
| GO:0000166 | nucleotide binding | 37.7358 | 4 | yes |
| GO:0017076 | purine nucleotide binding | 37.7358 | 5 | yes |
| GO:0032555 | purine ribonucleotide binding | 36.7925 | 4 | yes |
| GO:0035639 | purine ribonucleoside triphosphate binding | 35.8491 | 4 | yes |
| GO:0019900 | kinase binding | 26.4151 | 4 | no |
| GO:0019901 | protein kinase binding | 26.4151 | 5 | no |
| GO:0043169 | cation binding | 23.5849 | 4 | yes |
| GO:0030554 | adenyl nucleotide binding | 22.6415 | 6 | yes |
| GO:0046872 | metal ion binding | 22.6415 | 5 | yes |
| GO:0032559 | adenyl ribonucleotide binding | 21.6981 | 5 | yes |
| GO:0005524 | ATP binding | 20.7547 | 5 | yes |
| GO:0003723 | RNA binding | 16.0377 | 4 | yes |
| GO:0045296 | cadherin binding | 15.0943 | 4 | yes |
| GO:0016301 | kinase activity | 14.1509 | 4 | yes |
| GO:0016773 | phosphotransferase activity, alcohol group as acceptor | 14.1509 | 4 | yes |
| GO:0004674 | protein serine/threonine kinase activity | 11.3208 | 4 | yes |
| GO:0106310 | protein serine kinase activity | 11.3208 | 4 | yes |
| GO:0019887 | protein kinase regulator activity | 10.3774 | 4 | yes |
| GO:0048156 | tau protein binding | 7.5472 | 4 | yes |
| GO:0000287 | magnesium ion binding | 4.7170 | 6 | yes |
| GO:0050321 | tau-protein kinase activity | 3.7736 | 4 | yes |
| GO:0019209 | kinase activator activity | 2.8302 | 4 | yes |
| GO:0030295 | protein kinase activator activity | 2.8302 | 5 | yes |
Biological process
| Term | Name | % | Distance from top the of the tree | Annotated in MARK2_HUMAN |
|---|---|---|---|---|
| GO:0048522 | positive regulation of cellular process | 74.5283 | 4 | yes |
| GO:0048523 | negative regulation of cellular process | 58.4906 | 4 | no |
| GO:0051128 | regulation of cellular component organization | 56.6038 | 4 | yes |
| GO:0060255 | regulation of macromolecule metabolic process | 56.6038 | 4 | yes |
| GO:0031323 | regulation of cellular metabolic process | 53.7736 | 4 | yes |
| GO:0006996 | organelle organization | 50.9434 | 4 | yes |
| GO:0080090 | regulation of primary metabolic process | 50.0000 | 4 | yes |
| GO:0008104 | protein localization | 48.1132 | 4 | no |
| GO:0010646 | regulation of cell communication | 47.1698 | 4 | no |
| GO:0009893 | positive regulation of metabolic process | 46.2264 | 4 | yes |
| GO:0022607 | cellular component assembly | 45.2830 | 4 | no |
| GO:0010604 | positive regulation of macromolecule metabolic process | 42.4528 | 5 | yes |
| GO:0009889 | regulation of biosynthetic process | 41.5094 | 4 | no |
| GO:0009966 | regulation of signal transduction | 41.5094 | 4 | no |
| GO:0010556 | regulation of macromolecule biosynthetic process | 40.5660 | 5 | no |
| GO:0031326 | regulation of cellular biosynthetic process | 40.5660 | 5 | no |
| GO:0051246 | regulation of protein metabolic process | 39.6226 | 5 | yes |
| GO:0010468 | regulation of gene expression | 39.6226 | 6 | no |
| GO:0031325 | positive regulation of cellular metabolic process | 38.6792 | 5 | yes |
| GO:0051049 | regulation of transport | 38.6792 | 4 | no |
| GO:0071702 | organic substance transport | 36.7925 | 4 | no |
| GO:0060341 | regulation of cellular localization | 34.9057 | 4 | no |
| GO:0048584 | positive regulation of response to stimulus | 34.9057 | 4 | no |
| GO:0071705 | nitrogen compound transport | 33.9623 | 4 | no |
| GO:0009892 | negative regulation of metabolic process | 33.9623 | 4 | no |
| GO:0032880 | regulation of protein localization | 33.0189 | 5 | no |
| GO:0019220 | regulation of phosphate metabolic process | 32.0755 | 6 | yes |
| GO:0051174 | regulation of phosphorus metabolic process | 32.0755 | 5 | yes |
| GO:0031399 | regulation of protein modification process | 31.1321 | 6 | yes |
| GO:0010605 | negative regulation of macromolecule metabolic process | 31.1321 | 5 | no |
| GO:0010647 | positive regulation of cell communication | 31.1321 | 5 | no |
| GO:0023056 | positive regulation of signaling | 31.1321 | 4 | no |
| GO:0033043 | regulation of organelle organization | 30.1887 | 5 | yes |
| GO:0051130 | positive regulation of cellular component organization | 30.1887 | 5 | yes |
| GO:0031324 | negative regulation of cellular metabolic process | 30.1887 | 5 | no |
| GO:0045595 | regulation of cell differentiation | 30.1887 | 4 | no |
| GO:0009891 | positive regulation of biosynthetic process | 30.1887 | 5 | no |
| GO:0019219 | regulation of nucleobase-containing compound metabolic process | 30.1887 | 5 | no |
| GO:0044087 | regulation of cellular component biogenesis | 30.1887 | 4 | no |
| GO:1902531 | regulation of intracellular signal transduction | 30.1887 | 5 | no |
| GO:0031344 | regulation of cell projection organization | 29.2453 | 5 | yes |
| GO:0051247 | positive regulation of protein metabolic process | 29.2453 | 6 | yes |
| GO:0120035 | regulation of plasma membrane bounded cell projection organization | 29.2453 | 6 | yes |
| GO:0031328 | positive regulation of cellular biosynthetic process | 28.3019 | 6 | no |
| GO:0042981 | regulation of apoptotic process | 28.3019 | 5 | no |
| GO:0043067 | regulation of programmed cell death | 28.3019 | 4 | no |
| GO:0042325 | regulation of phosphorylation | 27.3585 | 7 | yes |
| GO:0001932 | regulation of protein phosphorylation | 26.4151 | 7 | yes |
| GO:0007010 | cytoskeleton organization | 26.4151 | 5 | yes |
| GO:0015031 | protein transport | 26.4151 | 4 | no |
| GO:0051050 | positive regulation of transport | 26.4151 | 4 | no |
| GO:0009967 | positive regulation of signal transduction | 26.4151 | 5 | no |
| GO:0010557 | positive regulation of macromolecule biosynthetic process | 26.4151 | 6 | no |
| GO:0048585 | negative regulation of response to stimulus | 26.4151 | 4 | no |
| GO:0051094 | positive regulation of developmental process | 25.4717 | 4 | no |
| GO:0043933 | protein-containing complex organization | 25.4717 | 4 | no |
| GO:0010648 | negative regulation of cell communication | 25.4717 | 5 | no |
| GO:0023057 | negative regulation of signaling | 25.4717 | 4 | no |
| GO:0051252 | regulation of RNA metabolic process | 25.4717 | 5 | no |
| GO:1903829 | positive regulation of protein localization | 24.5283 | 5 | no |
| GO:0006355 | regulation of DNA-templated transcription | 24.5283 | 7 | no |
| GO:2000145 | regulation of cell motility | 24.5283 | 4 | no |
| GO:2001141 | regulation of RNA biosynthetic process | 24.5283 | 6 | no |
| GO:0030334 | regulation of cell migration | 23.5849 | 5 | no |
| GO:0071310 | cellular response to organic substance | 23.5849 | 4 | no |
| GO:0043412 | macromolecule modification | 23.5849 | 4 | yes |
| GO:0065003 | protein-containing complex assembly | 23.5849 | 5 | no |
| GO:0009968 | negative regulation of signal transduction | 23.5849 | 5 | no |
| GO:0051240 | positive regulation of multicellular organismal process | 22.6415 | 4 | no |
| GO:0022603 | regulation of anatomical structure morphogenesis | 22.6415 | 4 | yes |
| GO:0036211 | protein modification process | 22.6415 | 4 | yes |
| GO:0051493 | regulation of cytoskeleton organization | 22.6415 | 6 | yes |
| GO:0042127 | regulation of cell population proliferation | 22.6415 | 4 | no |
| GO:0080134 | regulation of response to stress | 21.6981 | 4 | no |
| GO:0030030 | cell projection organization | 21.6981 | 4 | yes |
| GO:0043085 | positive regulation of catalytic activity | 21.6981 | 4 | yes |
| GO:0050804 | modulation of chemical synaptic transmission | 20.7547 | 5 | no |
| GO:0099177 | regulation of trans-synaptic signaling | 20.7547 | 4 | no |
| GO:1901701 | cellular response to oxygen-containing compound | 20.7547 | 4 | no |
| GO:0031401 | positive regulation of protein modification process | 20.7547 | 7 | yes |
| GO:0097435 | supramolecular fiber organization | 20.7547 | 4 | no |
| GO:0030155 | regulation of cell adhesion | 20.7547 | 4 | no |
| GO:0006796 | phosphate-containing compound metabolic process | 19.8113 | 4 | yes |
| GO:0010562 | positive regulation of phosphorus metabolic process | 19.8113 | 6 | yes |
| GO:0045937 | positive regulation of phosphate metabolic process | 19.8113 | 7 | yes |
| GO:0120036 | plasma membrane bounded cell projection organization | 19.8113 | 5 | yes |
| GO:0042327 | positive regulation of phosphorylation | 18.8679 | 8 | yes |
| GO:0001934 | positive regulation of protein phosphorylation | 17.9245 | 8 | yes |
| GO:0043549 | regulation of kinase activity | 17.9245 | 5 | yes |
| GO:0051338 | regulation of transferase activity | 17.9245 | 4 | yes |
| GO:0010975 | regulation of neuron projection development | 16.9811 | 7 | yes |
| GO:0031346 | positive regulation of cell projection organization | 16.9811 | 6 | yes |
| GO:0045859 | regulation of protein kinase activity | 16.0377 | 6 | yes |
| GO:0016310 | phosphorylation | 15.0943 | 5 | yes |
| GO:0006468 | protein phosphorylation | 13.2075 | 5 | yes |
| GO:0007005 | mitochondrion organization | 13.2075 | 5 | yes |
| GO:0031175 | neuron projection development | 13.2075 | 6 | yes |
| GO:0032886 | regulation of microtubule-based process | 13.2075 | 4 | yes |
| GO:0022604 | regulation of cell morphogenesis | 12.2642 | 5 | yes |
| GO:0070507 | regulation of microtubule cytoskeleton organization | 12.2642 | 5 | yes |
| GO:0033674 | positive regulation of kinase activity | 11.3208 | 6 | yes |
| GO:0051347 | positive regulation of transferase activity | 11.3208 | 5 | yes |
| GO:0045860 | positive regulation of protein kinase activity | 10.3774 | 7 | yes |
| GO:0022411 | cellular component disassembly | 9.4340 | 4 | yes |
| GO:0010976 | positive regulation of neuron projection development | 8.4906 | 7 | yes |
| GO:0016055 | Wnt signaling pathway | 8.4906 | 4 | yes |
| GO:0018193 | peptidyl-amino acid modification | 8.4906 | 5 | yes |
| GO:0001764 | neuron migration | 7.5472 | 4 | yes |
| GO:0018105 | peptidyl-serine phosphorylation | 6.6038 | 6 | yes |
| GO:0018209 | peptidyl-serine modification | 6.6038 | 6 | yes |
| GO:0035088 | establishment or maintenance of apical/basal cell polarity | 6.6038 | 4 | yes |
| GO:0043393 | regulation of protein binding | 6.6038 | 4 | yes |
| GO:0046777 | protein autophosphorylation | 6.6038 | 6 | yes |
| GO:1903008 | organelle disassembly | 6.6038 | 5 | yes |
| GO:0045197 | establishment or maintenance of epithelial cell apical/basal polarity | 5.6604 | 5 | yes |
| GO:0000422 | autophagy of mitochondrion | 3.7736 | 4 | yes |
| GO:0050770 | regulation of axonogenesis | 3.7736 | 5 | yes |
| GO:0018107 | peptidyl-threonine phosphorylation | 2.8302 | 6 | yes |
| GO:0018210 | peptidyl-threonine modification | 2.8302 | 6 | yes |
| GO:0032147 | activation of protein kinase activity | 2.8302 | 8 | yes |
| GO:0061564 | axon development | 2.8302 | 7 | yes |
| GO:1904526 | regulation of microtubule binding | 1.8868 | 5 | yes |
Disease
No data found.
All partners
| Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
|---|---|---|---|---|
| CBP_HUMAN | [view interactions] | Low throughput | no | yes |
| STK11_HUMAN | [view interactions] | Low throughput | no | yes |
| RFIP2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| KPCE_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| PKD1_HUMAN | [view interactions] | Low throughput | no | yes |
| BAIP2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| EIF2A_HUMAN | [view interactions] | Low throughput | no | yes |
| 1433F_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| 1433Z_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| UBP21_HUMAN | [view interactions] | Low throughput | no | no |
| UTRN_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| MTCL1_HUMAN | [view interactions] | Low throughput | no | yes |
| KI13B_HUMAN | [view interactions] | Low throughput | no | yes |
| ARHG2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| KPCI_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| 1433B_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| 1433G_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| 1433T_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| 1433E_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| MARK2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| CRTC2_HUMAN | [view interactions] | Low throughput | no | yes |
| KPCD1_HUMAN | [view interactions] | Low throughput | no | yes |
| TAOK1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| TAU_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| PINK1_HUMAN | [view interactions] | Low throughput | no | yes |
| KCC1A_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| AKT1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| HDAC7_HUMAN | [view interactions] | Low throughput | no | no |
| PTPA_HUMAN | [view interactions] | Low throughput | no | yes |
| DMD_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| RHOA_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| GAB1_HUMAN | [view interactions] | Low throughput | no | yes |
| GAB2_HUMAN | [view interactions] | Low throughput | no | yes |
| PARD3_HUMAN | [view interactions] | Low throughput | no | yes |
| RNF41_HUMAN | [view interactions] | Low throughput | no | yes |
| CD44_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| STK4_HUMAN | [view interactions] | Low throughput | no | yes |
| STK3_HUMAN | [view interactions] | Low throughput | no | yes |
| ZRAN1_HUMAN | [view interactions] | High throughput | no | yes |
| VIGLN_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RAF1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| TRI67_HUMAN | [view interactions] | High throughput | no | no |
| UBE2O_HUMAN | [view interactions] | High throughput | no | yes |
| AGO1_HUMAN | [view interactions] | High throughput | no | no |
| AGO2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AGO3_HUMAN | [view interactions] | High throughput | no | yes |
| AGO4_HUMAN | [view interactions] | High throughput | no | no |
| SNTB1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| STIM1_HUMAN | [view interactions] | High throughput | no | yes |
| DHR12_HUMAN | [view interactions] | High throughput | no | yes |
| SPD2A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DTNB_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| DDX6L_HUMAN | [view interactions] | High throughput | no | yes |
| PP6R2_HUMAN | [view interactions] | High throughput | no | no |
| TPX2_HUMAN | [view interactions] | High throughput | no | yes |
| GCSP_HUMAN | [view interactions] | High throughput | no | yes |
| DVL2_HUMAN | [view interactions] | High throughput | no | yes |
| SPOP_HUMAN | [view interactions] | High throughput | no | no |
| ANLN_HUMAN | [view interactions] | High throughput | no | yes |
| UBP36_HUMAN | [view interactions] | High throughput | no | yes |
| UBE2H_HUMAN | [view interactions] | High throughput | no | yes |
| TNIP1_HUMAN | [view interactions] | High throughput | no | yes |
| NF1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| SPPL3_HUMAN | [view interactions] | High throughput | no | no |
| NEDD4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NED4L_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SMUF1_HUMAN | [view interactions] | High throughput | no | yes |
| FBX7_HUMAN | [view interactions] | High throughput | no | yes |
| HS90A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HS90B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HSP74_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CDC37_HUMAN | [view interactions] | High throughput | no | yes |
| PFD2_HUMAN | [view interactions] | High throughput | no | yes |
| CADH1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| GRRE1_HUMAN | [view interactions] | High throughput | no | no |
| RET_HUMAN | [view interactions] | High throughput | no | yes |
| PTPRA_HUMAN | [view interactions] | High throughput | no | yes |
| MIC26_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RMD3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DNJ5B_HUMAN | [view interactions] | High throughput | no | no |
| DNJC5_HUMAN | [view interactions] | High throughput | no | yes |
| KAPCA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ARF6_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| B3GA1_HUMAN | [view interactions] | High throughput | no | yes |
| CK052_HUMAN | [view interactions] | High throughput | no | no |
| CAV1_HUMAN | [view interactions] | High throughput | no | no |
| CXAR_HUMAN | [view interactions] | High throughput | no | yes |
| DIRA3_HUMAN | [view interactions] | High throughput | no | yes |
| RCAS1_HUMAN | [view interactions] | High throughput | no | yes |
| E41LA_HUMAN | [view interactions] | High throughput | no | yes |
| EZRI_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| FLOT1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CXA1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PAR6G_HUMAN | [view interactions] | High throughput | no | no |
| CXD3_HUMAN | [view interactions] | High throughput | no | no |
| LAMP2_HUMAN | [view interactions] | High throughput | no | yes |
| SNTB2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| LAMP3_HUMAN | [view interactions] | High throughput | no | no |
| SMAP_HUMAN | [view interactions] | High throughput | no | yes |
| LTOR1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LCK_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| MPPA_HUMAN | [view interactions] | High throughput | no | yes |
| LMAN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LYN_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| MARK1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| MARE3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CERT_HUMAN | [view interactions] | High throughput | no | yes |
| MARCS_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| UTP18_HUMAN | [view interactions] | High throughput | no | yes |
| AFAD_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| OCLN_HUMAN | [view interactions] | High throughput | no | no |
| MARK3_HUMAN | [view interactions] | High throughput | no | yes |
| PANX1_HUMAN | [view interactions] | High throughput | no | no |
| PHLP1_HUMAN | [view interactions] | High throughput | no | yes |
| RB11A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CLAP2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RAB2A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RAB35_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KINH_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RAB5A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RAB5C_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CE85L_HUMAN | [view interactions] | High throughput | no | yes |
| RAB9A_HUMAN | [view interactions] | High throughput | no | yes |
| DTNA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| STX4_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| FUCO_HUMAN | [view interactions] | High throughput | no | yes |
| STX6_HUMAN | [view interactions] | High throughput | no | yes |
| GASP1_HUMAN | [view interactions] | High throughput | no | yes |
| STX7_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SQSTM_HUMAN | [view interactions] | High throughput | no | yes |
| TRI36_HUMAN | [view interactions] | High throughput | no | no |
| ZFPL1_HUMAN | [view interactions] | High throughput | no | yes |
| ATG9A_HUMAN | [view interactions] | High throughput | no | yes |
| TRPM7_HUMAN | [view interactions] | High throughput | no | no |
| DTX2_HUMAN | [view interactions] | High throughput | no | yes |
| FRYL_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PARP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RSF1_HUMAN | [view interactions] | High throughput | no | yes |
| ESYT2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| 2AAA_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| MUC18_HUMAN | [view interactions] | High throughput | no | yes |
| NUP42_HUMAN | [view interactions] | High throughput | no | no |
| SSR3_HUMAN | [view interactions] | High throughput | no | yes |
| FXL16_HUMAN | [view interactions] | High throughput | no | yes |
| HERC2_HUMAN | [view interactions] | High throughput | no | yes |
| PRDX3_HUMAN | [view interactions] | High throughput | no | yes |
| CCD82_HUMAN | [view interactions] | High throughput | no | yes |
| CAZA2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PDCD7_HUMAN | [view interactions] | High throughput | no | no |
| 2A5E_HUMAN | [view interactions] | High throughput | no | yes |
| CLAP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CAZA1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| WDR46_HUMAN | [view interactions] | High throughput | no | yes |
| ERI3_HUMAN | [view interactions] | High throughput | no | yes |
| ARK72_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| EEA1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PPHLN_HUMAN | [view interactions] | High throughput | no | yes |
| KI67_HUMAN | [view interactions] | High throughput | no | no |
| LRRK2_HUMAN | [view interactions] | High throughput | no | yes |
| CSF1_HUMAN | [view interactions] | High throughput | no | no |
| SYUA_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| MTR1A_HUMAN | [view interactions] | High throughput | no | no |
| HTRA4_HUMAN | [view interactions] | High throughput | no | no |
| DAPK1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MTCL2_HUMAN | [view interactions] | High throughput | no | yes |
| CAPZB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| WDR6_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RM22_HUMAN | [view interactions] | High throughput | no | yes |
| CDC5L_HUMAN | [view interactions] | High throughput | no | yes |
| PTBP3_HUMAN | [view interactions] | High throughput | no | no |
| ITM2B_HUMAN | [view interactions] | High throughput | no | yes |
| RYBP_HUMAN | [view interactions] | High throughput | no | no |
| RIMS1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HCN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DYR1A_HUMAN | [view interactions] | High throughput | no | yes |
| KPYM_HUMAN | [view interactions] | High throughput | no | yes |
| M3K3_HUMAN | [view interactions] | High throughput | no | no |
| 1433S_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CBY1_HUMAN | [view interactions] | High throughput | no | no |
| ESR1_HUMAN | [view interactions] | High throughput | no | no |
| PTPRD_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| TMM17_HUMAN | [view interactions] | High throughput | no | yes |
| DCTN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CEP89_HUMAN | [view interactions] | High throughput | no | no |
| LAMP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RASK_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RASN_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RASH_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| KCNJ2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| EGFR_HUMAN | [view interactions] | High throughput | no | no |
| INSR_HUMAN | [view interactions] | High throughput | no | yes |
| NTRK1_HUMAN | [view interactions] | High throughput | no | yes |
| ROR2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| STYK1_HUMAN | [view interactions] | High throughput | no | yes |
| CFTR_HUMAN | [view interactions] | High throughput | no | no |
| KCNK3_HUMAN | [view interactions] | High throughput | no | no |
| CSKP_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RFA2_HUMAN | [view interactions] | High throughput | no | yes |
| KIFA3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PAR3L_HUMAN | [view interactions] | High throughput | no | yes |
| MARK4_HUMAN | [view interactions] | High throughput | no | yes |
| TAD2A_HUMAN | [view interactions] | High throughput | no | no |
| AAPK1_HUMAN | [view interactions] | High throughput | no | no |
| PAR6A_HUMAN | [view interactions] | High throughput | no | yes |
| FOXP3_HUMAN | [view interactions] | High throughput | no | no |
| TERA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AURKB_HUMAN | [view interactions] | High throughput | no | yes |
| CDN1A_HUMAN | [view interactions] | High throughput | no | no |
| CEP57_HUMAN | [view interactions] | High throughput | no | yes |
| CCDC8_HUMAN | [view interactions] | High throughput | no | yes |
| EED_HUMAN | [view interactions] | High throughput | no | yes |
| NP1L5_HUMAN | [view interactions] | High throughput | no | yes |
| CDK15_HUMAN | [view interactions] | High throughput | no | no |
| ROA1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AP2M1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| APC_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| LDHD_HUMAN | [view interactions] | High throughput | no | yes |
| DLG5_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CAMP2_HUMAN | [view interactions] | High throughput | no | yes |
| CENPE_HUMAN | [view interactions] | High throughput | no | no |
| CYH1_HUMAN | [view interactions] | High throughput | no | no |
| SRSF8_HUMAN | [view interactions] | High throughput | no | yes |
| TMCC2_HUMAN | [view interactions] | High throughput | no | yes |
| LRC33_HUMAN | [view interactions] | High throughput | no | yes |
| NUAK2_HUMAN | [view interactions] | High throughput | no | yes |
| SIX2_HUMAN | [view interactions] | High throughput | no | no |
| MANS1_HUMAN | [view interactions] | High throughput | no | yes |
| CAD19_HUMAN | [view interactions] | High throughput | no | no |
| CAV3_HUMAN | [view interactions] | High throughput | no | no |
| GSK3A_HUMAN | [view interactions] | High throughput | no | yes |
| HDAC4_HUMAN | [view interactions] | High throughput | no | yes |
| ESR2_HUMAN | [view interactions] | High throughput | no | no |
| VIR_HUMAN | [view interactions] | High throughput | no | yes |
| RC3H1_HUMAN | [view interactions] | High throughput | no | yes |
| RC3H2_HUMAN | [view interactions] | High throughput | no | yes |
| A16L1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TRPV1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| APEX1_HUMAN | [view interactions] | High throughput | no | yes |
| CC14A_HUMAN | [view interactions] | High throughput | no | yes |
| RGS14_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PKHA4_HUMAN | [view interactions] | High throughput | no | yes |
| SC6A4_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| GLI1_HUMAN | [view interactions] | High throughput | no | no |
| IF16_HUMAN | [view interactions] | High throughput | no | no |
| UFL1_HUMAN | [view interactions] | High throughput | no | yes |
| DDRGK_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SMAD4_HUMAN | [view interactions] | High throughput | no | yes |
| KCNE3_HUMAN | [view interactions] | High throughput | no | yes |
| FGF13_HUMAN | [view interactions] | High throughput | no | no |
| GPSM3_HUMAN | [view interactions] | High throughput | no | no |
| TMM74_HUMAN | [view interactions] | High throughput | no | no |
| MACC1_HUMAN | [view interactions] | High throughput | no | yes |
| PHB2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| 2ABB_HUMAN | [view interactions] | High throughput | no | yes |
| CDC42_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RAC1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RHOG_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RHOJ_HUMAN | [view interactions] | High throughput | no | yes |
| RHOQ_HUMAN | [view interactions] | High throughput | no | no |
| RAC2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RAC3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RHOB_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RHOC_HUMAN | [view interactions] | High throughput | no | no |
| RHOD_HUMAN | [view interactions] | High throughput | no | no |
| RHOF_HUMAN | [view interactions] | High throughput | no | no |
| RHOU_HUMAN | [view interactions] | High throughput | no | no |
| RHOV_HUMAN | [view interactions] | High throughput | no | no |
| RHOH_HUMAN | [view interactions] | High throughput | no | yes |
| RND1_HUMAN | [view interactions] | High throughput | no | no |
| RND2_HUMAN | [view interactions] | High throughput | no | no |
| RND3_HUMAN | [view interactions] | High throughput | no | no |
| RANB9_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SOX2_HUMAN | [view interactions] | High throughput | no | yes |
| ARP2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ARL8A_HUMAN | [view interactions] | High throughput | no | no |
| ARL8B_HUMAN | [view interactions] | High throughput | no | yes |
| ERF3A_HUMAN | [view interactions] | High throughput | no | yes |
| CCDC9_HUMAN | [view interactions] | High throughput | no | yes |
| JKIP1_HUMAN | [view interactions] | High throughput | no | no |
| RBM25_HUMAN | [view interactions] | High throughput | no | yes |
| PR40A_HUMAN | [view interactions] | High throughput | no | no |
| MIS12_HUMAN | [view interactions] | High throughput | no | yes |
| TPC11_HUMAN | [view interactions] | High throughput | no | no |
| TPC2A_HUMAN | [view interactions] | High throughput | no | yes |
| MYCN_HUMAN | [view interactions] | High throughput | no | no |
| MYC_HUMAN | [view interactions] | High throughput | no | yes |
| PRKN_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |