TRPV1_HUMAN
Evidence for PS localization
Functions
Ligand-activated non-selective calcium permeant cation channel involved in detection of noxious chemical and thermal stimuli. Seems to mediate proton influx and may be involved in intracellular acidosis in nociceptive neurons. Involved in mediation of inflammatory pain and hyperalgesia. Sensitized by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases, which involves PKC isozymes and PCL. Activation by vanilloids, like capsaicin, and temperatures higher than 42 degrees Celsius, exhibits a time- and Ca(2+)-dependent outward rectification, followed by a long-lasting refractory state. Mild extracellular acidic pH (6.5) potentiates channel activation by noxious heat and vanilloids, whereas acidic conditions (pH <6) directly activate the channel. Can be activated by endogenous compounds, including 12-hydroperoxytetraenoic acid and bradykinin. Acts as ionotropic endocannabinoid receptor with central neuromodulatory effects. Triggers a form of long-term depression (TRPV1-LTD) mediated by the endocannabinoid anandamine in the hippocampus and nucleus accumbens by affecting AMPA receptors endocytosis. [View more on UniProt]
Protein features
Binary interactions with known binding regions
Interacting region for partners were not defined.
Network
Isoforms
Disease-causing germline mutations
No data found.
Linear motifs
No annotated instance was found. To search for linear motifs, use the ELM prediction server.
Fingerprint
Molecular function
| Term | Name | % | Distance from the top of the tree | Annotated in TRPV1_HUMAN |
|---|---|---|---|---|
| GO:0017076 | purine nucleotide binding | 38.2716 | 4 | yes |
| GO:0032555 | purine ribonucleotide binding | 38.2716 | 4 | yes |
| GO:0035639 | purine ribonucleoside triphosphate binding | 38.2716 | 4 | yes |
| GO:0046872 | metal ion binding | 37.0370 | 4 | yes |
| GO:0005524 | ATP binding | 30.8642 | 5 | yes |
| GO:0030554 | adenyl nucleotide binding | 30.8642 | 5 | yes |
| GO:0032559 | adenyl ribonucleotide binding | 30.8642 | 5 | yes |
| GO:0003723 | RNA binding | 25.9259 | 4 | no |
| GO:0035091 | phosphatidylinositol binding | 9.8765 | 4 | yes |
| GO:0008324 | cation transmembrane transporter activity | 3.7037 | 4 | yes |
| GO:0015085 | calcium ion transmembrane transporter activity | 3.7037 | 6 | yes |
| GO:0022890 | inorganic cation transmembrane transporter activity | 3.7037 | 4 | yes |
| GO:0046873 | metal ion transmembrane transporter activity | 3.7037 | 5 | yes |
| GO:0005216 | ion channel activity | 2.4691 | 4 | yes |
| GO:0005217 | intracellular ligand-gated ion channel activity | 2.4691 | 6 | yes |
| GO:0005230 | extracellular ligand-gated ion channel activity | 2.4691 | 6 | yes |
| GO:0005231 | excitatory extracellular ligand-gated ion channel activity | 2.4691 | 7 | yes |
| GO:0005244 | voltage-gated ion channel activity | 2.4691 | 4 | yes |
| GO:0005245 | voltage-gated calcium channel activity | 2.4691 | 6 | yes |
| GO:0005261 | cation channel activity | 2.4691 | 5 | yes |
| GO:0005262 | calcium channel activity | 2.4691 | 6 | yes |
| GO:0015267 | channel activity | 2.4691 | 4 | yes |
| GO:0015276 | ligand-gated ion channel activity | 2.4691 | 5 | yes |
| GO:0015278 | calcium-release channel activity | 2.4691 | 7 | yes |
| GO:0017081 | chloride channel regulator activity | 2.4691 | 4 | yes |
| GO:0022832 | voltage-gated channel activity | 2.4691 | 6 | yes |
| GO:0022834 | ligand-gated channel activity | 2.4691 | 6 | yes |
| GO:0022836 | gated channel activity | 2.4691 | 5 | yes |
| GO:0022843 | voltage-gated cation channel activity | 2.4691 | 5 | yes |
| GO:0097603 | temperature-gated ion channel activity | 2.4691 | 5 | yes |
| GO:0099094 | ligand-gated cation channel activity | 2.4691 | 6 | yes |
| GO:0099604 | ligand-gated calcium channel activity | 2.4691 | 7 | yes |
Biological process
| Term | Name | % | Distance from top the of the tree | Annotated in TRPV1_HUMAN |
|---|---|---|---|---|
| GO:0048522 | positive regulation of cellular process | 44.4444 | 4 | yes |
| GO:0060255 | regulation of macromolecule metabolic process | 43.2099 | 4 | yes |
| GO:0051171 | regulation of nitrogen compound metabolic process | 41.9753 | 4 | yes |
| GO:0080090 | regulation of primary metabolic process | 41.9753 | 4 | yes |
| GO:0031323 | regulation of cellular metabolic process | 40.7407 | 4 | yes |
| GO:0048523 | negative regulation of cellular process | 40.7407 | 4 | yes |
| GO:0022607 | cellular component assembly | 38.2716 | 4 | yes |
| GO:0006996 | organelle organization | 34.5679 | 4 | no |
| GO:0051128 | regulation of cellular component organization | 33.3333 | 4 | no |
| GO:0008104 | protein localization | 32.0988 | 4 | no |
| GO:0051049 | regulation of transport | 30.8642 | 4 | yes |
| GO:0010468 | regulation of gene expression | 28.3951 | 5 | yes |
| GO:0051246 | regulation of protein metabolic process | 28.3951 | 5 | no |
| GO:0010646 | regulation of cell communication | 27.1605 | 4 | no |
| GO:0009893 | positive regulation of metabolic process | 25.9259 | 4 | yes |
| GO:0051173 | positive regulation of nitrogen compound metabolic process | 24.6914 | 5 | yes |
| GO:0019219 | regulation of nucleobase-containing compound metabolic process | 23.4568 | 5 | yes |
| GO:0031325 | positive regulation of cellular metabolic process | 23.4568 | 5 | yes |
| GO:0007010 | cytoskeleton organization | 23.4568 | 5 | no |
| GO:0043933 | protein-containing complex organization | 22.2222 | 4 | yes |
| GO:0010604 | positive regulation of macromolecule metabolic process | 22.2222 | 5 | no |
| GO:0009889 | regulation of biosynthetic process | 20.9877 | 4 | yes |
| GO:0010556 | regulation of macromolecule biosynthetic process | 20.9877 | 5 | yes |
| GO:0031326 | regulation of cellular biosynthetic process | 20.9877 | 5 | yes |
| GO:0051050 | positive regulation of transport | 20.9877 | 4 | yes |
| GO:0065003 | protein-containing complex assembly | 20.9877 | 5 | yes |
| GO:0071702 | organic substance transport | 20.9877 | 4 | yes |
| GO:0051130 | positive regulation of cellular component organization | 20.9877 | 5 | no |
| GO:0060341 | regulation of cellular localization | 20.9877 | 4 | no |
| GO:0009892 | negative regulation of metabolic process | 19.7531 | 4 | yes |
| GO:0010605 | negative regulation of macromolecule metabolic process | 18.5185 | 5 | yes |
| GO:0045595 | regulation of cell differentiation | 18.5185 | 4 | yes |
| GO:0051252 | regulation of RNA metabolic process | 18.5185 | 5 | yes |
| GO:0071310 | cellular response to organic substance | 18.5185 | 4 | yes |
| GO:0071705 | nitrogen compound transport | 18.5185 | 4 | yes |
| GO:0010941 | regulation of cell death | 16.0494 | 4 | yes |
| GO:0031324 | negative regulation of cellular metabolic process | 16.0494 | 5 | yes |
| GO:0051172 | negative regulation of nitrogen compound metabolic process | 16.0494 | 5 | yes |
| GO:0051240 | positive regulation of multicellular organismal process | 16.0494 | 4 | yes |
| GO:0006355 | regulation of DNA-templated transcription | 14.8148 | 6 | yes |
| GO:0010243 | response to organonitrogen compound | 14.8148 | 4 | yes |
| GO:0042981 | regulation of apoptotic process | 14.8148 | 6 | yes |
| GO:0043067 | regulation of programmed cell death | 14.8148 | 5 | yes |
| GO:0044057 | regulation of system process | 14.8148 | 4 | yes |
| GO:1903506 | regulation of nucleic acid-templated transcription | 14.8148 | 7 | yes |
| GO:2001141 | regulation of RNA biosynthetic process | 14.8148 | 6 | yes |
| GO:0009891 | positive regulation of biosynthetic process | 13.5802 | 5 | yes |
| GO:0014070 | response to organic cyclic compound | 13.5802 | 4 | yes |
| GO:0031328 | positive regulation of cellular biosynthetic process | 13.5802 | 6 | yes |
| GO:1901701 | cellular response to oxygen-containing compound | 12.3457 | 4 | yes |
| GO:0006357 | regulation of transcription by RNA polymerase II | 11.1111 | 7 | yes |
| GO:0051046 | regulation of secretion | 11.1111 | 5 | yes |
| GO:0060284 | regulation of cell development | 11.1111 | 5 | yes |
| GO:0070848 | response to growth factor | 11.1111 | 4 | yes |
| GO:1901699 | cellular response to nitrogen compound | 11.1111 | 4 | yes |
| GO:1903522 | regulation of blood circulation | 11.1111 | 5 | yes |
| GO:0006811 | ion transport | 9.8765 | 4 | yes |
| GO:0008016 | regulation of heart contraction | 9.8765 | 6 | yes |
| GO:0071363 | cellular response to growth factor stimulus | 9.8765 | 5 | yes |
| GO:0071407 | cellular response to organic cyclic compound | 9.8765 | 5 | yes |
| GO:0071417 | cellular response to organonitrogen compound | 9.8765 | 4 | yes |
| GO:0034097 | response to cytokine | 8.6420 | 4 | yes |
| GO:0051093 | negative regulation of developmental process | 8.6420 | 4 | yes |
| GO:0006812 | cation transport | 7.4074 | 5 | yes |
| GO:0009890 | negative regulation of biosynthetic process | 7.4074 | 5 | yes |
| GO:0010558 | negative regulation of macromolecule biosynthetic process | 7.4074 | 6 | yes |
| GO:0010942 | positive regulation of cell death | 7.4074 | 5 | yes |
| GO:0030001 | metal ion transport | 7.4074 | 6 | yes |
| GO:0031327 | negative regulation of cellular biosynthetic process | 7.4074 | 6 | yes |
| GO:0043065 | positive regulation of apoptotic process | 7.4074 | 7 | yes |
| GO:0043068 | positive regulation of programmed cell death | 7.4074 | 6 | yes |
| GO:0045596 | negative regulation of cell differentiation | 7.4074 | 5 | yes |
| GO:0045934 | negative regulation of nucleobase-containing compound metabolic process | 7.4074 | 6 | yes |
| GO:0051241 | negative regulation of multicellular organismal process | 7.4074 | 4 | yes |
| GO:0051253 | negative regulation of RNA metabolic process | 7.4074 | 6 | yes |
| GO:0071345 | cellular response to cytokine stimulus | 7.4074 | 5 | yes |
| GO:1990090 | cellular response to nerve growth factor stimulus | 7.4074 | 4 | yes |
| GO:0043434 | response to peptide hormone | 6.1728 | 4 | yes |
| GO:0045892 | negative regulation of DNA-templated transcription | 6.1728 | 7 | yes |
| GO:0046903 | secretion | 6.1728 | 4 | yes |
| GO:1901652 | response to peptide | 6.1728 | 4 | yes |
| GO:1902679 | negative regulation of RNA biosynthetic process | 6.1728 | 7 | yes |
| GO:1903507 | negative regulation of nucleic acid-templated transcription | 6.1728 | 8 | yes |
| GO:0006816 | calcium ion transport | 4.9383 | 7 | yes |
| GO:0010447 | response to acidic pH | 4.9383 | 4 | yes |
| GO:0010721 | negative regulation of cell development | 4.9383 | 6 | yes |
| GO:0034605 | cellular response to heat | 4.9383 | 4 | yes |
| GO:0034612 | response to tumor necrosis factor | 4.9383 | 5 | yes |
| GO:0045428 | regulation of nitric oxide biosynthetic process | 4.9383 | 6 | yes |
| GO:0045429 | positive regulation of nitric oxide biosynthetic process | 4.9383 | 7 | yes |
| GO:0051047 | positive regulation of secretion | 4.9383 | 5 | yes |
| GO:0051259 | protein complex oligomerization | 4.9383 | 6 | yes |
| GO:0051881 | regulation of mitochondrial membrane potential | 4.9383 | 4 | yes |
| GO:0071356 | cellular response to tumor necrosis factor | 4.9383 | 6 | yes |
| GO:0080164 | regulation of nitric oxide metabolic process | 4.9383 | 5 | yes |
| GO:0098655 | cation transmembrane transport | 4.9383 | 4 | yes |
| GO:0098660 | inorganic ion transmembrane transport | 4.9383 | 4 | yes |
| GO:0098662 | inorganic cation transmembrane transport | 4.9383 | 5 | yes |
| GO:1904407 | positive regulation of nitric oxide metabolic process | 4.9383 | 6 | yes |
| GO:0002790 | peptide secretion | 3.7037 | 5 | yes |
| GO:0006936 | muscle contraction | 3.7037 | 4 | yes |
| GO:0006954 | inflammatory response | 3.7037 | 4 | yes |
| GO:0007600 | sensory perception | 3.7037 | 4 | yes |
| GO:0014074 | response to purine-containing compound | 3.7037 | 5 | yes |
| GO:0015833 | peptide transport | 3.7037 | 5 | yes |
| GO:0042116 | macrophage activation | 3.7037 | 4 | yes |
| GO:0042886 | amide transport | 3.7037 | 5 | yes |
| GO:0043279 | response to alkaloid | 3.7037 | 5 | yes |
| GO:0045822 | negative regulation of heart contraction | 3.7037 | 6 | yes |
| GO:0046683 | response to organophosphorus | 3.7037 | 4 | yes |
| GO:0050954 | sensory perception of mechanical stimulus | 3.7037 | 5 | yes |
| GO:0051260 | protein homooligomerization | 3.7037 | 7 | yes |
| GO:0051262 | protein tetramerization | 3.7037 | 7 | yes |
| GO:0070588 | calcium ion transmembrane transport | 3.7037 | 6 | yes |
| GO:0071467 | cellular response to pH | 3.7037 | 4 | yes |
| GO:0071468 | cellular response to acidic pH | 3.7037 | 5 | yes |
| GO:1903523 | negative regulation of blood circulation | 3.7037 | 5 | yes |
| GO:0000122 | negative regulation of transcription by RNA polymerase II | 2.4691 | 8 | yes |
| GO:0001660 | fever generation | 2.4691 | 5 | yes |
| GO:0001774 | microglial cell activation | 2.4691 | 4 | yes |
| GO:0002526 | acute inflammatory response | 2.4691 | 5 | yes |
| GO:0003085 | negative regulation of systemic arterial blood pressure | 2.4691 | 5 | yes |
| GO:0006820 | anion transport | 2.4691 | 5 | yes |
| GO:0006835 | dicarboxylic acid transport | 2.4691 | 7 | yes |
| GO:0006865 | amino acid transport | 2.4691 | 5 | yes |
| GO:0006939 | smooth muscle contraction | 2.4691 | 5 | yes |
| GO:0006953 | acute-phase response | 2.4691 | 6 | yes |
| GO:0010459 | negative regulation of heart rate | 2.4691 | 4 | yes |
| GO:0010917 | negative regulation of mitochondrial membrane potential | 2.4691 | 5 | yes |
| GO:0014047 | glutamate secretion | 2.4691 | 4 | yes |
| GO:0014832 | urinary bladder smooth muscle contraction | 2.4691 | 7 | yes |
| GO:0014848 | urinary tract smooth muscle contraction | 2.4691 | 6 | yes |
| GO:0015711 | organic anion transport | 2.4691 | 5 | yes |
| GO:0015800 | acidic amino acid transport | 2.4691 | 6 | yes |
| GO:0015849 | organic acid transport | 2.4691 | 5 | yes |
| GO:0016048 | detection of temperature stimulus | 2.4691 | 4 | yes |
| GO:0031649 | heat generation | 2.4691 | 4 | yes |
| GO:0033198 | response to ATP | 2.4691 | 4 | yes |
| GO:0044058 | regulation of digestive system process | 2.4691 | 5 | yes |
| GO:0045776 | negative regulation of blood pressure | 2.4691 | 4 | yes |
| GO:0045837 | negative regulation of membrane potential | 2.4691 | 4 | yes |
| GO:0046942 | carboxylic acid transport | 2.4691 | 6 | yes |
| GO:0050907 | detection of chemical stimulus involved in sensory perception | 2.4691 | 4 | yes |
| GO:0050951 | sensory perception of temperature stimulus | 2.4691 | 5 | yes |
| GO:0050955 | thermoception | 2.4691 | 6 | yes |
| GO:0050960 | detection of temperature stimulus involved in thermoception | 2.4691 | 5 | yes |
| GO:0050961 | detection of temperature stimulus involved in sensory perception | 2.4691 | 4 | yes |
| GO:0050965 | detection of temperature stimulus involved in sensory perception of pain | 2.4691 | 5 | yes |
| GO:0050968 | detection of chemical stimulus involved in sensory perception of pain | 2.4691 | 5 | yes |
| GO:0051289 | protein homotetramerization | 2.4691 | 8 | yes |
| GO:0060083 | smooth muscle contraction involved in micturition | 2.4691 | 8 | yes |
| GO:0060453 | regulation of gastric acid secretion | 2.4691 | 6 | yes |
| GO:0060454 | positive regulation of gastric acid secretion | 2.4691 | 6 | yes |
| GO:0060456 | positive regulation of digestive system process | 2.4691 | 5 | yes |
| GO:0062149 | detection of stimulus involved in sensory perception of pain | 2.4691 | 4 | yes |
| GO:0071312 | cellular response to alkaloid | 2.4691 | 5 | yes |
| GO:0071318 | cellular response to ATP | 2.4691 | 5 | yes |
| GO:0071502 | cellular response to temperature stimulus | 2.4691 | 4 | yes |
| GO:0090210 | regulation of establishment of blood-brain barrier | 2.4691 | 6 | yes |
| GO:0090212 | negative regulation of establishment of blood-brain barrier | 2.4691 | 7 | yes |
| GO:0097553 | calcium ion transmembrane import into cytosol | 2.4691 | 7 | yes |
| GO:0098657 | import into cell | 2.4691 | 4 | yes |
| GO:0098659 | inorganic cation import across plasma membrane | 2.4691 | 5 | yes |
| GO:0098703 | calcium ion import across plasma membrane | 2.4691 | 6 | yes |
| GO:0099587 | inorganic ion import across plasma membrane | 2.4691 | 4 | yes |
| GO:1901594 | response to capsazepine | 2.4691 | 4 | yes |
Disease
| Term | Name | % | Distance from top the of the tree | Annotated in TRPV1_HUMAN |
|---|---|---|---|---|
| DOID:114 | heart disease | 4.9383 | 3 | no |
| DOID:0050700 | cardiomyopathy | 3.7037 | 4 | no |
| DOID:0060036 | intrinsic cardiomyopathy | 3.7037 | 5 | no |
| DOID:2843 | long QT syndrome | 2.4691 | 6 | no |
All partners
| Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
|---|---|---|---|---|
| SYT9_HUMAN | [view interactions] | Low throughput | no | no |
| SNAPN_HUMAN | [view interactions] | Low throughput | no | yes |
| TRPV1_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| CALM2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| CALM3_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| CALM1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| OS9_HUMAN | [view interactions] | Low throughput | no | yes |
| FAF1_HUMAN | [view interactions] | Low throughput | no | yes |
| EGFR_HUMAN | [view interactions] | Low throughput | no | no |
| CBL_HUMAN | [view interactions] | Low throughput | no | yes |
| RFIP3_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| AKAP5_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| KAPCA_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| TBB6_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| U2AF2_HUMAN | [view interactions] | High throughput | no | yes |
| UACA_HUMAN | [view interactions] | High throughput | no | yes |
| VINC_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ABLM2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ACTZ_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ADDB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AIFM1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CAPZB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CO6A1_HUMAN | [view interactions] | High throughput | no | no |
| CSRP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DDX17_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DYST_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SYEP_HUMAN | [view interactions] | High throughput | no | yes |
| SYFB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FPPS_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FIBA_HUMAN | [view interactions] | High throughput | no | no |
| HBE_HUMAN | [view interactions] | High throughput | no | no |
| HNRPM_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SYIC_HUMAN | [view interactions] | High throughput | no | yes |
| LIMA1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| MARK2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MYO1D_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RB11B_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RAB35_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RS2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SAM50_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SSRA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TWF1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| VMA5A_HUMAN | [view interactions] | High throughput | no | no |
| YBOX3_HUMAN | [view interactions] | High throughput | no | yes |
| SEPT2_HUMAN | [view interactions] | High throughput | no | no |
| ACLY_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ACTB_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ACTN2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ADDA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AP3D1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ARL8A_HUMAN | [view interactions] | High throughput | no | no |
| ATAD1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AT2A2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ATX2_HUMAN | [view interactions] | High throughput | no | yes |
| ATX2L_HUMAN | [view interactions] | High throughput | no | no |
| BMP2K_HUMAN | [view interactions] | High throughput | no | yes |
| CATA_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CHM4B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CLCB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| COEA1_HUMAN | [view interactions] | High throughput | no | no |
| COPB_HUMAN | [view interactions] | High throughput | no | yes |
| COPG1_HUMAN | [view interactions] | High throughput | no | yes |
| CRIP2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CSDE1_HUMAN | [view interactions] | High throughput | no | yes |
| CATB_HUMAN | [view interactions] | High throughput | no | yes |
| DAB2_HUMAN | [view interactions] | High throughput | no | yes |
| DCTN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DDX3Y_HUMAN | [view interactions] | High throughput | no | yes |
| DDX6_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DNJC9_HUMAN | [view interactions] | High throughput | no | yes |
| DOC11_HUMAN | [view interactions] | High throughput | no | yes |
| DC1L2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| IF2G_HUMAN | [view interactions] | High throughput | no | yes |
| EIF3B_HUMAN | [view interactions] | High throughput | no | yes |
| IF4G3_HUMAN | [view interactions] | High throughput | no | yes |
| E41L3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ESYT1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FCHO2_HUMAN | [view interactions] | High throughput | no | yes |
| FKB1A_HUMAN | [view interactions] | High throughput | no | yes |
| FKBP2_HUMAN | [view interactions] | High throughput | no | yes |
| FLNA_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| FLNB_HUMAN | [view interactions] | High throughput | no | no |
| H2A1_HUMAN | [view interactions] | High throughput | no | yes |
| H2A2A_HUMAN | [view interactions] | High throughput | no | yes |
| H2A1B_HUMAN | [view interactions] | High throughput | no | yes |
| H2A1D_HUMAN | [view interactions] | High throughput | no | yes |
| H2A1A_HUMAN | [view interactions] | High throughput | no | yes |
| H2AJ_HUMAN | [view interactions] | High throughput | no | yes |
| H2A3_HUMAN | [view interactions] | High throughput | no | yes |
| H2A2B_HUMAN | [view interactions] | High throughput | no | yes |
| H2A1J_HUMAN | [view interactions] | High throughput | no | yes |
| H2AX_HUMAN | [view interactions] | High throughput | no | yes |
| H2A1C_HUMAN | [view interactions] | High throughput | no | yes |
| H2A1H_HUMAN | [view interactions] | High throughput | no | yes |
| H2A2C_HUMAN | [view interactions] | High throughput | no | yes |
| H13_HUMAN | [view interactions] | High throughput | no | no |
| HNRH1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HNRH2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HS90A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ITA6_HUMAN | [view interactions] | High throughput | no | yes |
| K1C28_HUMAN | [view interactions] | High throughput | no | no |
| LASP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LIMC1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| LRRF2_HUMAN | [view interactions] | High throughput | no | yes |
| LSM12_HUMAN | [view interactions] | High throughput | no | yes |
| MK01_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MBNL1_HUMAN | [view interactions] | High throughput | no | yes |
| RM11_HUMAN | [view interactions] | High throughput | no | yes |
| MYO7A_HUMAN | [view interactions] | High throughput | no | yes |
| NACAM_HUMAN | [view interactions] | High throughput | no | no |
| NDUBA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NEXN_HUMAN | [view interactions] | High throughput | no | yes |
| NUFP2_HUMAN | [view interactions] | High throughput | no | no |
| ODO1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| OSBL3_HUMAN | [view interactions] | High throughput | no | yes |
| PFKAM_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PFKAP_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PKHA6_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| PLLP_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| PRVA_HUMAN | [view interactions] | High throughput | no | yes |
| PYM1_HUMAN | [view interactions] | High throughput | no | yes |
| RAI14_HUMAN | [view interactions] | High throughput | no | yes |
| RALA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RAP1A_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RBM14_HUMAN | [view interactions] | High throughput | no | yes |
| RBMX_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RL38_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RS27_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RS27L_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RRBP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RUFY3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SAR1B_HUMAN | [view interactions] | High throughput | no | yes |
| SH3L1_HUMAN | [view interactions] | High throughput | no | yes |
| SND1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CYTSA_HUMAN | [view interactions] | High throughput | no | yes |
| SRPRB_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| THY1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TCTP_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TRPV2_HUMAN | [view interactions] | High throughput | no | yes |
| T22D4_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| TBB1_HUMAN | [view interactions] | High throughput | no | yes |
| P2RX3_HUMAN | [view interactions] | Computational | no | no |
| AKAP1_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| TRPM3_HUMAN | [view interactions] | Computational | no | no |
| KCC2B_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| TRPA1_HUMAN | [view interactions] | Computational | no | no |
| TKN1_HUMAN | [view interactions] | Computational | no | yes |
| NAPEP_HUMAN | [view interactions] | Computational | no | yes |
| CNR1_HUMAN | [view interactions] | Computational | no | yes |
| GPR55_HUMAN | [view interactions] | Computational | no | no |
| FAAH1_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| NGF_HUMAN | [view interactions] | Computational | no | no |
| SRC_HUMAN | [view entry] [view interactions] | Computational | yes | no |
| KCC2D_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| ASIC3_HUMAN | [view interactions] | Computational | no | no |
| TRPM5_HUMAN | [view interactions] | Computational | no | no |
| KAPCB_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| ANK1_HUMAN | [view entry] [view interactions] | Computational | yes | no |
| CALC_HUMAN | [view interactions] | Computational | no | no |
| TRPM8_HUMAN | [view interactions] | Computational | no | no |
| KPCE_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| SCNAA_HUMAN | [view interactions] | Computational | no | no |
| KAPCG_HUMAN | [view interactions] | Computational | no | no |
| TRPC3_HUMAN | [view interactions] | Computational | no | no |
| TRPC1_HUMAN | [view interactions] | Computational | no | yes |
| PIRT_HUMAN | [view interactions] | Computational | no | no |
| ANO1_HUMAN | [view interactions] | Computational | no | no |
| AKT1_HUMAN | [view entry] [view interactions] | Computational | yes | yes |