SYFB_HUMAN
Evidence for PS localization
Functions
Protein features
Binary interactions with known binding regions
To display all evidence describing the interaction with a partner, click on the protein name left to the bars.
Network
Isoforms
Disease-causing germline mutations
No data found.
Linear motifs
No annotated instance was found. To search for linear motifs, use the ELM prediction server.
Fingerprint
Molecular function
| Term | Name | % | Distance from the top of the tree | Annotated in SYFB_HUMAN |
|---|---|---|---|---|
| GO:0000166 | nucleotide binding | 47.8261 | 4 | yes |
| GO:0043168 | anion binding | 47.8261 | 4 | yes |
| GO:0017076 | purine nucleotide binding | 45.6522 | 5 | yes |
| GO:0032555 | purine ribonucleotide binding | 45.6522 | 4 | yes |
| GO:0035639 | purine ribonucleoside triphosphate binding | 45.6522 | 4 | yes |
| GO:0005524 | ATP binding | 36.9565 | 5 | yes |
| GO:0030554 | adenyl nucleotide binding | 36.9565 | 6 | yes |
| GO:0032559 | adenyl ribonucleotide binding | 36.9565 | 5 | yes |
| GO:0003723 | RNA binding | 32.6087 | 4 | yes |
| GO:0043169 | cation binding | 23.9130 | 4 | yes |
| GO:0046872 | metal ion binding | 23.9130 | 5 | yes |
| GO:0019900 | kinase binding | 21.7391 | 4 | no |
| GO:0000287 | magnesium ion binding | 6.5217 | 6 | yes |
| GO:0004812 | aminoacyl-tRNA ligase activity | 6.5217 | 4 | yes |
| GO:0004826 | phenylalanine-tRNA ligase activity | 6.5217 | 5 | yes |
| GO:0140101 | catalytic activity, acting on a tRNA | 6.5217 | 4 | yes |
Biological process
| Term | Name | % | Distance from top the of the tree | Annotated in SYFB_HUMAN |
|---|---|---|---|---|
| GO:0048522 | positive regulation of cellular process | 69.5652 | 4 | no |
| GO:0031323 | regulation of cellular metabolic process | 60.8696 | 4 | no |
| GO:0060255 | regulation of macromolecule metabolic process | 60.8696 | 4 | no |
| GO:0009893 | positive regulation of metabolic process | 56.5217 | 4 | no |
| GO:0048523 | negative regulation of cellular process | 56.5217 | 4 | no |
| GO:0051128 | regulation of cellular component organization | 54.3478 | 4 | no |
| GO:0080090 | regulation of primary metabolic process | 54.3478 | 4 | no |
| GO:0009889 | regulation of biosynthetic process | 52.1739 | 4 | no |
| GO:0022607 | cellular component assembly | 50.0000 | 4 | yes |
| GO:0010556 | regulation of macromolecule biosynthetic process | 50.0000 | 5 | no |
| GO:0031326 | regulation of cellular biosynthetic process | 50.0000 | 5 | no |
| GO:0010604 | positive regulation of macromolecule metabolic process | 47.8261 | 5 | no |
| GO:0010646 | regulation of cell communication | 47.8261 | 4 | no |
| GO:0009966 | regulation of signal transduction | 45.6522 | 4 | no |
| GO:0010468 | regulation of gene expression | 45.6522 | 6 | no |
| GO:0031325 | positive regulation of cellular metabolic process | 45.6522 | 5 | no |
| GO:0043933 | protein-containing complex organization | 43.4783 | 4 | yes |
| GO:0009892 | negative regulation of metabolic process | 43.4783 | 4 | no |
| GO:0010605 | negative regulation of macromolecule metabolic process | 41.3043 | 5 | no |
| GO:0019219 | regulation of nucleobase-containing compound metabolic process | 41.3043 | 5 | no |
| GO:0043067 | regulation of programmed cell death | 41.3043 | 4 | no |
| GO:0048584 | positive regulation of response to stimulus | 41.3043 | 4 | no |
| GO:0051246 | regulation of protein metabolic process | 41.3043 | 5 | no |
| GO:0042981 | regulation of apoptotic process | 39.1304 | 5 | no |
| GO:1902531 | regulation of intracellular signal transduction | 39.1304 | 5 | no |
| GO:0031324 | negative regulation of cellular metabolic process | 39.1304 | 5 | no |
| GO:0009891 | positive regulation of biosynthetic process | 36.9565 | 5 | no |
| GO:0051252 | regulation of RNA metabolic process | 36.9565 | 5 | no |
| GO:0006355 | regulation of DNA-templated transcription | 34.7826 | 7 | no |
| GO:0006996 | organelle organization | 34.7826 | 4 | no |
| GO:0044087 | regulation of cellular component biogenesis | 34.7826 | 4 | no |
| GO:0048585 | negative regulation of response to stimulus | 34.7826 | 4 | no |
| GO:2001141 | regulation of RNA biosynthetic process | 34.7826 | 6 | no |
| GO:0009890 | negative regulation of biosynthetic process | 34.7826 | 5 | no |
| GO:0009059 | macromolecule biosynthetic process | 32.6087 | 4 | yes |
| GO:0009967 | positive regulation of signal transduction | 32.6087 | 5 | no |
| GO:0010557 | positive regulation of macromolecule biosynthetic process | 32.6087 | 6 | no |
| GO:0010647 | positive regulation of cell communication | 32.6087 | 5 | no |
| GO:0010648 | negative regulation of cell communication | 32.6087 | 5 | no |
| GO:0023056 | positive regulation of signaling | 32.6087 | 4 | no |
| GO:0023057 | negative regulation of signaling | 32.6087 | 4 | no |
| GO:0031328 | positive regulation of cellular biosynthetic process | 32.6087 | 6 | no |
| GO:0031399 | regulation of protein modification process | 32.6087 | 6 | no |
| GO:0051247 | positive regulation of protein metabolic process | 32.6087 | 6 | no |
| GO:0010558 | negative regulation of macromolecule biosynthetic process | 32.6087 | 6 | no |
| GO:0031327 | negative regulation of cellular biosynthetic process | 32.6087 | 6 | no |
| GO:0060341 | regulation of cellular localization | 32.6087 | 4 | no |
| GO:0006796 | phosphate-containing compound metabolic process | 30.4348 | 4 | no |
| GO:0009968 | negative regulation of signal transduction | 30.4348 | 5 | no |
| GO:0019220 | regulation of phosphate metabolic process | 30.4348 | 6 | no |
| GO:0051174 | regulation of phosphorus metabolic process | 30.4348 | 5 | no |
| GO:0032880 | regulation of protein localization | 30.4348 | 5 | no |
| GO:0071310 | cellular response to organic substance | 30.4348 | 4 | no |
| GO:0065003 | protein-containing complex assembly | 28.2609 | 5 | yes |
| GO:0006357 | regulation of transcription by RNA polymerase II | 28.2609 | 8 | no |
| GO:0036211 | protein modification process | 28.2609 | 4 | no |
| GO:0043412 | macromolecule modification | 28.2609 | 4 | no |
| GO:0045935 | positive regulation of nucleobase-containing compound metabolic process | 28.2609 | 5 | no |
| GO:0009894 | regulation of catabolic process | 28.2609 | 4 | no |
| GO:0051049 | regulation of transport | 28.2609 | 4 | no |
| GO:0051130 | positive regulation of cellular component organization | 28.2609 | 5 | no |
| GO:1901701 | cellular response to oxygen-containing compound | 28.2609 | 4 | no |
| GO:0042127 | regulation of cell population proliferation | 26.0870 | 4 | no |
| GO:0051241 | negative regulation of multicellular organismal process | 26.0870 | 4 | no |
| GO:0080134 | regulation of response to stress | 26.0870 | 4 | no |
| GO:0032101 | regulation of response to external stimulus | 26.0870 | 4 | no |
| GO:0051240 | positive regulation of multicellular organismal process | 26.0870 | 4 | no |
| GO:0031401 | positive regulation of protein modification process | 23.9130 | 7 | no |
| GO:0045595 | regulation of cell differentiation | 23.9130 | 4 | no |
| GO:1902533 | positive regulation of intracellular signal transduction | 23.9130 | 6 | no |
| GO:2000145 | regulation of cell motility | 23.9130 | 4 | no |
| GO:0033043 | regulation of organelle organization | 23.9130 | 5 | no |
| GO:0051094 | positive regulation of developmental process | 23.9130 | 4 | no |
| GO:0090304 | nucleic acid metabolic process | 21.7391 | 4 | yes |
| GO:0001932 | regulation of protein phosphorylation | 21.7391 | 7 | no |
| GO:0008104 | protein localization | 21.7391 | 4 | no |
| GO:0042325 | regulation of phosphorylation | 21.7391 | 7 | no |
| GO:0051248 | negative regulation of protein metabolic process | 21.7391 | 6 | no |
| GO:0051254 | positive regulation of RNA metabolic process | 21.7391 | 6 | no |
| GO:0009896 | positive regulation of catabolic process | 21.7391 | 5 | no |
| GO:0022603 | regulation of anatomical structure morphogenesis | 21.7391 | 4 | no |
| GO:0030155 | regulation of cell adhesion | 21.7391 | 4 | no |
| GO:0030334 | regulation of cell migration | 21.7391 | 5 | no |
| GO:1901566 | organonitrogen compound biosynthetic process | 17.3913 | 4 | yes |
| GO:0006412 | translation | 15.2174 | 4 | yes |
| GO:0016070 | RNA metabolic process | 13.0435 | 5 | yes |
| GO:0051259 | protein complex oligomerization | 10.8696 | 6 | yes |
| GO:0051262 | protein tetramerization | 10.8696 | 7 | yes |
| GO:0051290 | protein heterotetramerization | 8.6957 | 8 | yes |
| GO:0051291 | protein heterooligomerization | 8.6957 | 7 | yes |
| GO:0006399 | tRNA metabolic process | 6.5217 | 6 | yes |
| GO:0006418 | tRNA aminoacylation for protein translation | 6.5217 | 6 | yes |
| GO:0006432 | phenylalanyl-tRNA aminoacylation | 6.5217 | 7 | yes |
| GO:0043038 | amino acid activation | 6.5217 | 4 | yes |
| GO:0043039 | tRNA aminoacylation | 6.5217 | 5 | yes |
Disease
No data found.
All partners
| Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
|---|---|---|---|---|
| SYFA_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| MSRA_HUMAN | [view interactions] | Low throughput | no | no |
| SYFB_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| E2AK2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| OTUB1_HUMAN | [view interactions] | High throughput | no | yes |
| WRP73_HUMAN | [view interactions] | High throughput | no | no |
| T2EB_HUMAN | [view interactions] | High throughput | no | yes |
| MAGBA_HUMAN | [view interactions] | High throughput | no | no |
| APBA3_HUMAN | [view interactions] | High throughput | no | yes |
| FIBB_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| GPX7_HUMAN | [view interactions] | High throughput | no | no |
| UBP47_HUMAN | [view interactions] | High throughput | no | yes |
| PAK4_HUMAN | [view interactions] | High throughput | no | yes |
| LRRK2_HUMAN | [view interactions] | High throughput | no | yes |
| GRN_HUMAN | [view interactions] | High throughput | no | no |
| SH2D3_HUMAN | [view interactions] | High throughput | no | no |
| RAC1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| PTPRR_HUMAN | [view interactions] | High throughput | no | yes |
| FGFR1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GATA3_HUMAN | [view interactions] | High throughput | no | no |
| P53_HUMAN | [view interactions] | High throughput | no | no |
| VCAM1_HUMAN | [view interactions] | High throughput | no | no |
| FINC_HUMAN | [view interactions] | High throughput | no | yes |
| STAT1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| MB212_HUMAN | [view interactions] | High throughput | no | no |
| MK03_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| JUN_HUMAN | [view interactions] | High throughput | no | yes |
| BCAR1_HUMAN | [view interactions] | High throughput | no | yes |
| FXR1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| EGLN_HUMAN | [view interactions] | High throughput | no | no |
| HDAC4_HUMAN | [view interactions] | High throughput | no | yes |
| CEP63_HUMAN | [view interactions] | High throughput | no | yes |
| ACTB_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| HD_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ATX1_HUMAN | [view interactions] | High throughput | no | yes |
| HDGF_HUMAN | [view interactions] | High throughput | no | yes |
| FOXR1_HUMAN | [view interactions] | High throughput | no | no |
| GLI1_HUMAN | [view interactions] | High throughput | no | no |
| ESR1_HUMAN | [view interactions] | High throughput | no | no |
| EZRI_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CFTR_HUMAN | [view interactions] | High throughput | no | no |
| SF3B4_HUMAN | [view interactions] | High throughput | no | yes |
| UBA5_HUMAN | [view interactions] | High throughput | no | yes |
| CD4_HUMAN | [view interactions] | High throughput | no | no |
| ITA4_HUMAN | [view interactions] | High throughput | no | no |
| NXF1_HUMAN | [view interactions] | High throughput | no | yes |
| EED_HUMAN | [view interactions] | High throughput | no | yes |
| DTX3_HUMAN | [view interactions] | High throughput | no | yes |
| TEKT2_HUMAN | [view interactions] | High throughput | no | no |
| NTRK1_HUMAN | [view interactions] | High throughput | no | yes |
| MCM2_HUMAN | [view interactions] | High throughput | no | no |
| UBE2A_HUMAN | [view interactions] | High throughput | no | no |
| HSP7C_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MTCH2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| U5S1_HUMAN | [view interactions] | High throughput | no | yes |
| AAR2_HUMAN | [view interactions] | High throughput | no | no |
| ARI1_HUMAN | [view interactions] | High throughput | no | yes |
| ESR2_HUMAN | [view interactions] | High throughput | no | no |
| HEXI1_HUMAN | [view interactions] | High throughput | no | yes |
| WWOX_HUMAN | [view interactions] | High throughput | no | yes |
| RECQ4_HUMAN | [view interactions] | High throughput | no | yes |
| MYC_HUMAN | [view interactions] | High throughput | no | yes |
| A16L1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PHB1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TCTP_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NR2C2_HUMAN | [view interactions] | High throughput | no | yes |
| TRPV1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| MTMRE_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TIP_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GSK3B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| BIRC3_HUMAN | [view interactions] | High throughput | no | no |
| LMBRL_HUMAN | [view interactions] | High throughput | no | no |
| TIF1B_HUMAN | [view interactions] | High throughput | no | yes |
| PKHA4_HUMAN | [view interactions] | High throughput | no | yes |
| BACD3_HUMAN | [view interactions] | High throughput | no | yes |
| PINK1_HUMAN | [view interactions] | High throughput | no | yes |
| ZCH18_HUMAN | [view interactions] | High throughput | no | yes |
| ANR55_HUMAN | [view interactions] | High throughput | no | yes |
| ANLN_HUMAN | [view interactions] | High throughput | no | yes |
| MD2L2_HUMAN | [view interactions] | High throughput | no | yes |
| BRD4_HUMAN | [view interactions] | High throughput | no | yes |
| PD1L1_HUMAN | [view interactions] | High throughput | no | no |
| SKA3_HUMAN | [view interactions] | High throughput | no | no |
| FZR1_HUMAN | [view interactions] | High throughput | no | no |
| GHRL_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| DCAM_HUMAN | [view interactions] | High throughput | no | yes |
| PACE1_HUMAN | [view interactions] | High throughput | no | yes |
| ARSF_HUMAN | [view interactions] | High throughput | no | no |
| CENPM_HUMAN | [view interactions] | High throughput | no | yes |
| MTPN_HUMAN | [view interactions] | High throughput | no | yes |
| ZBTB9_HUMAN | [view interactions] | High throughput | no | no |
| BRK1_HUMAN | [view interactions] | High throughput | no | no |
| PITX1_HUMAN | [view interactions] | High throughput | no | yes |
| HSBP1_HUMAN | [view interactions] | High throughput | no | no |
| SPRTN_HUMAN | [view interactions] | High throughput | no | yes |
| ZRAN1_HUMAN | [view interactions] | High throughput | no | yes |
| CLU_HUMAN | [view interactions] | High throughput | no | yes |
| RAC2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RHOA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RHOB_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RHOC_HUMAN | [view interactions] | High throughput | no | no |
| RHOU_HUMAN | [view interactions] | High throughput | no | no |
| RHOV_HUMAN | [view interactions] | High throughput | no | no |
| RHBT2_HUMAN | [view interactions] | High throughput | no | no |
| RND1_HUMAN | [view interactions] | High throughput | no | no |
| SAR1B_HUMAN | [view interactions] | High throughput | no | yes |
| ANM1_HUMAN | [view interactions] | High throughput | no | yes |
| TERA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PRKN_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| BAP1_HUMAN | [view interactions] | High throughput | no | yes |
| ACE2_HUMAN | [view interactions] | High throughput | no | no |
| BRCA1_HUMAN | [view interactions] | High throughput | no | yes |
| RAF1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| TRI67_HUMAN | [view interactions] | High throughput | no | no |
| RHG24_HUMAN | [view interactions] | High throughput | no | yes |
| ADA10_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CFAH_HUMAN | [view interactions] | High throughput | no | no |
| TET5C_HUMAN | [view interactions] | High throughput | no | yes |
| EZH2_HUMAN | [view interactions] | High throughput | no | no |
| PTEN_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RICTR_HUMAN | [view interactions] | High throughput | no | yes |
| SMC5_HUMAN | [view interactions] | High throughput | no | yes |
| UBE2H_HUMAN | [view interactions] | High throughput | no | yes |
| CTBL1_HUMAN | [view interactions] | High throughput | no | yes |
| INT5_HUMAN | [view interactions] | High throughput | no | no |
| LEO1_HUMAN | [view interactions] | High throughput | no | yes |
| EGFR_HUMAN | [view interactions] | High throughput | no | no |
| SUMO2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SYIC_HUMAN | [view interactions] | High throughput | no | yes |
| UBP8_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| SYAC_HUMAN | [view interactions] | High throughput | no | yes |
| FAF1_HUMAN | [view interactions] | High throughput | no | yes |
| GANAB_HUMAN | [view interactions] | High throughput | no | yes |
| PLOD2_HUMAN | [view interactions] | High throughput | no | yes |
| UGPA_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| XRCC6_HUMAN | [view interactions] | High throughput | no | yes |
| PUR2_HUMAN | [view interactions] | High throughput | no | yes |
| HS105_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PUR6_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RANB3_HUMAN | [view interactions] | High throughput | no | yes |
| RL24_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RLA0_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RLA1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| SET_HUMAN | [view interactions] | High throughput | no | yes |
| SF01_HUMAN | [view interactions] | High throughput | no | yes |
| SPT5H_HUMAN | [view interactions] | High throughput | no | yes |
| SWP70_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| SYTC_HUMAN | [view interactions] | High throughput | no | yes |
| SYTC2_HUMAN | [view interactions] | High throughput | no | yes |
| OGT1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TCPG_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DRG1_HUMAN | [view interactions] | High throughput | no | yes |
| RL19_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RIR1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PP1R8_HUMAN | [view interactions] | High throughput | no | yes |
| DGUOK_HUMAN | [view interactions] | High throughput | no | yes |
| ASM3B_HUMAN | [view interactions] | High throughput | no | no |
| MIPEP_HUMAN | [view interactions] | High throughput | no | yes |
| ACTC_HUMAN | [view interactions] | High throughput | no | no |
| LEG9_HUMAN | [view interactions] | High throughput | no | yes |
| GCR_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NAA40_HUMAN | [view interactions] | High throughput | no | no |
| TOLIP_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CCNF_HUMAN | [view interactions] | High throughput | no | no |
| RFA1_HUMAN | [view interactions] | High throughput | no | yes |
| RFA2_HUMAN | [view interactions] | High throughput | no | yes |
| RFA3_HUMAN | [view interactions] | High throughput | no | yes |
| GLUT4_HUMAN | [view interactions] | High throughput | no | no |
| SLX4_HUMAN | [view interactions] | High throughput | no | yes |
| DDA1_HUMAN | [view interactions] | High throughput | no | yes |