FIBB_HUMAN
Evidence for PS localization
Functions
Cleaved by the protease thrombin to yield monomers which, together with fibrinogen alpha (FGA) and fibrinogen gamma (FGG), polymerize to form an insoluble fibrin matrix. Fibrin has a major function in hemostasis as one of the primary components of blood clots. In addition, functions during the early stages of wound repair to stabilize the lesion and guide cell migration during re-epithelialization. Was originally thought to be essential for platelet aggregation, based on in vitro studies using anticoagulated blood. However subsequent studies have shown that it is not absolutely required for thrombus formation in vivo. Enhances expression of SELP in activated platelets. Maternal fibrinogen is essential for successful pregnancy. Fibrin deposition is also associated with infection, where it protects against IFNG-mediated hemorrhage. May also facilitate the antibacterial immune response via both innate and T-cell mediated pathways. [View more on UniProt]
Protein features
Binary interactions with known binding regions
To display all evidence describing the interaction with a partner, click on the protein name left to the bars.
Network
Isoforms
Disease-causing germline mutations
No data found.
Linear motifs
No annotated instance was found. To search for linear motifs, use the ELM prediction server.
Fingerprint
Molecular function
| Term | Name | % | Distance from the top of the tree | Annotated in FIBB_HUMAN |
|---|---|---|---|---|
| GO:0046872 | metal ion binding | 30.0000 | 4 | no |
| GO:0017076 | purine nucleotide binding | 28.3333 | 4 | no |
| GO:0032555 | purine ribonucleotide binding | 28.3333 | 4 | no |
| GO:0035639 | purine ribonucleoside triphosphate binding | 28.3333 | 4 | no |
| GO:0005524 | ATP binding | 21.6667 | 5 | no |
| GO:0030554 | adenyl nucleotide binding | 21.6667 | 5 | no |
| GO:0032559 | adenyl ribonucleotide binding | 21.6667 | 5 | no |
Biological process
| Term | Name | % | Distance from top the of the tree | Annotated in FIBB_HUMAN |
|---|---|---|---|---|
| GO:0048523 | negative regulation of cellular process | 53.3333 | 4 | yes |
| GO:0048522 | positive regulation of cellular process | 46.6667 | 4 | yes |
| GO:0051171 | regulation of nitrogen compound metabolic process | 45.0000 | 4 | no |
| GO:0010646 | regulation of cell communication | 43.3333 | 4 | yes |
| GO:0031323 | regulation of cellular metabolic process | 43.3333 | 4 | no |
| GO:0060255 | regulation of macromolecule metabolic process | 43.3333 | 4 | no |
| GO:0080090 | regulation of primary metabolic process | 43.3333 | 4 | no |
| GO:0009966 | regulation of signal transduction | 38.3333 | 4 | yes |
| GO:0022607 | cellular component assembly | 35.0000 | 4 | yes |
| GO:0010941 | regulation of cell death | 30.0000 | 4 | yes |
| GO:0051246 | regulation of protein metabolic process | 30.0000 | 5 | no |
| GO:0009967 | positive regulation of signal transduction | 28.3333 | 5 | yes |
| GO:0010647 | positive regulation of cell communication | 28.3333 | 5 | yes |
| GO:0023056 | positive regulation of signaling | 28.3333 | 4 | yes |
| GO:0042981 | regulation of apoptotic process | 28.3333 | 6 | yes |
| GO:0043067 | regulation of programmed cell death | 28.3333 | 5 | yes |
| GO:0048584 | positive regulation of response to stimulus | 28.3333 | 4 | yes |
| GO:0051049 | regulation of transport | 28.3333 | 4 | yes |
| GO:0051240 | positive regulation of multicellular organismal process | 28.3333 | 4 | yes |
| GO:0009893 | positive regulation of metabolic process | 28.3333 | 4 | no |
| GO:1902531 | regulation of intracellular signal transduction | 26.6667 | 5 | yes |
| GO:0031325 | positive regulation of cellular metabolic process | 26.6667 | 5 | no |
| GO:0006996 | organelle organization | 26.6667 | 4 | no |
| GO:0009889 | regulation of biosynthetic process | 26.6667 | 4 | no |
| GO:0009892 | negative regulation of metabolic process | 26.6667 | 4 | no |
| GO:0010468 | regulation of gene expression | 26.6667 | 5 | no |
| GO:0031326 | regulation of cellular biosynthetic process | 26.6667 | 5 | no |
| GO:0043933 | protein-containing complex organization | 25.0000 | 4 | yes |
| GO:0010604 | positive regulation of macromolecule metabolic process | 25.0000 | 5 | no |
| GO:0051173 | positive regulation of nitrogen compound metabolic process | 25.0000 | 5 | no |
| GO:0008104 | protein localization | 25.0000 | 4 | no |
| GO:0010605 | negative regulation of macromolecule metabolic process | 25.0000 | 5 | no |
| GO:0051128 | regulation of cellular component organization | 25.0000 | 4 | no |
| GO:0071702 | organic substance transport | 25.0000 | 4 | no |
| GO:0045595 | regulation of cell differentiation | 23.3333 | 4 | yes |
| GO:0051094 | positive regulation of developmental process | 23.3333 | 4 | yes |
| GO:0071310 | cellular response to organic substance | 23.3333 | 4 | yes |
| GO:0080134 | regulation of response to stress | 23.3333 | 4 | yes |
| GO:0019220 | regulation of phosphate metabolic process | 23.3333 | 6 | no |
| GO:0042325 | regulation of phosphorylation | 23.3333 | 7 | no |
| GO:0051174 | regulation of phosphorus metabolic process | 23.3333 | 5 | no |
| GO:0016192 | vesicle-mediated transport | 23.3333 | 4 | no |
| GO:0010556 | regulation of macromolecule biosynthetic process | 23.3333 | 5 | no |
| GO:0051172 | negative regulation of nitrogen compound metabolic process | 23.3333 | 5 | no |
| GO:0071705 | nitrogen compound transport | 23.3333 | 4 | no |
| GO:0010648 | negative regulation of cell communication | 21.6667 | 5 | yes |
| GO:0023057 | negative regulation of signaling | 21.6667 | 4 | yes |
| GO:0060548 | negative regulation of cell death | 21.6667 | 5 | yes |
| GO:0065003 | protein-containing complex assembly | 21.6667 | 5 | yes |
| GO:0001932 | regulation of protein phosphorylation | 21.6667 | 7 | no |
| GO:0031399 | regulation of protein modification process | 21.6667 | 6 | no |
| GO:0036211 | protein modification process | 21.6667 | 4 | no |
| GO:0043412 | macromolecule modification | 21.6667 | 4 | no |
| GO:0006355 | regulation of DNA-templated transcription | 21.6667 | 6 | no |
| GO:0019219 | regulation of nucleobase-containing compound metabolic process | 21.6667 | 5 | no |
| GO:0031324 | negative regulation of cellular metabolic process | 21.6667 | 5 | no |
| GO:0051252 | regulation of RNA metabolic process | 21.6667 | 5 | no |
| GO:1903506 | regulation of nucleic acid-templated transcription | 21.6667 | 7 | no |
| GO:2001141 | regulation of RNA biosynthetic process | 21.6667 | 6 | no |
| GO:0022603 | regulation of anatomical structure morphogenesis | 20.0000 | 4 | yes |
| GO:0048585 | negative regulation of response to stimulus | 20.0000 | 4 | yes |
| GO:0060341 | regulation of cellular localization | 20.0000 | 4 | yes |
| GO:1902533 | positive regulation of intracellular signal transduction | 20.0000 | 6 | yes |
| GO:0009968 | negative regulation of signal transduction | 18.3333 | 5 | yes |
| GO:0043066 | negative regulation of apoptotic process | 18.3333 | 7 | yes |
| GO:0043069 | negative regulation of programmed cell death | 18.3333 | 6 | yes |
| GO:0045597 | positive regulation of cell differentiation | 18.3333 | 5 | yes |
| GO:0051050 | positive regulation of transport | 18.3333 | 4 | yes |
| GO:0032101 | regulation of response to external stimulus | 16.6667 | 4 | yes |
| GO:0032880 | regulation of protein localization | 16.6667 | 5 | yes |
| GO:0043408 | regulation of MAPK cascade | 16.6667 | 6 | yes |
| GO:0030155 | regulation of cell adhesion | 15.0000 | 4 | yes |
| GO:0044057 | regulation of system process | 15.0000 | 4 | yes |
| GO:0051241 | negative regulation of multicellular organismal process | 15.0000 | 4 | yes |
| GO:0060627 | regulation of vesicle-mediated transport | 15.0000 | 4 | yes |
| GO:0010810 | regulation of cell-substrate adhesion | 13.3333 | 5 | yes |
| GO:0010038 | response to metal ion | 11.6667 | 4 | yes |
| GO:0010720 | positive regulation of cell development | 11.6667 | 6 | yes |
| GO:0043410 | positive regulation of MAPK cascade | 11.6667 | 7 | yes |
| GO:0045785 | positive regulation of cell adhesion | 11.6667 | 5 | yes |
| GO:0051223 | regulation of protein transport | 11.6667 | 5 | yes |
| GO:0060284 | regulation of cell development | 11.6667 | 5 | yes |
| GO:0070201 | regulation of establishment of protein localization | 11.6667 | 6 | yes |
| GO:0070372 | regulation of ERK1 and ERK2 cascade | 11.6667 | 7 | yes |
| GO:1903829 | positive regulation of protein localization | 11.6667 | 5 | yes |
| GO:0003018 | vascular process in circulatory system | 10.0000 | 4 | yes |
| GO:0007160 | cell-matrix adhesion | 10.0000 | 4 | yes |
| GO:0022407 | regulation of cell-cell adhesion | 10.0000 | 5 | yes |
| GO:0022604 | regulation of cell morphogenesis | 10.0000 | 5 | yes |
| GO:0032870 | cellular response to hormone stimulus | 10.0000 | 4 | yes |
| GO:0034097 | response to cytokine | 10.0000 | 4 | yes |
| GO:0051046 | regulation of secretion | 10.0000 | 5 | yes |
| GO:0051047 | positive regulation of secretion | 10.0000 | 5 | yes |
| GO:0051592 | response to calcium ion | 10.0000 | 5 | yes |
| GO:0070374 | positive regulation of ERK1 and ERK2 cascade | 10.0000 | 8 | yes |
| GO:1903522 | regulation of blood circulation | 10.0000 | 5 | yes |
| GO:0006508 | proteolysis | 8.3333 | 4 | yes |
| GO:0010769 | regulation of cell morphogenesis involved in differentiation | 8.3333 | 6 | yes |
| GO:0010770 | positive regulation of cell morphogenesis involved in differentiation | 8.3333 | 7 | yes |
| GO:0010811 | positive regulation of cell-substrate adhesion | 8.3333 | 6 | yes |
| GO:0022409 | positive regulation of cell-cell adhesion | 8.3333 | 6 | yes |
| GO:0032102 | negative regulation of response to external stimulus | 8.3333 | 5 | yes |
| GO:0034109 | homotypic cell-cell adhesion | 8.3333 | 4 | yes |
| GO:0050708 | regulation of protein secretion | 8.3333 | 5 | yes |
| GO:0051222 | positive regulation of protein transport | 8.3333 | 5 | yes |
| GO:0070527 | platelet aggregation | 8.3333 | 5 | yes |
| GO:0070555 | response to interleukin-1 | 8.3333 | 5 | yes |
| GO:1903034 | regulation of response to wounding | 8.3333 | 5 | yes |
| GO:1903530 | regulation of secretion by cell | 8.3333 | 4 | yes |
| GO:1903532 | positive regulation of secretion by cell | 8.3333 | 5 | yes |
| GO:1904951 | positive regulation of establishment of protein localization | 8.3333 | 6 | yes |
| GO:2001233 | regulation of apoptotic signaling pathway | 8.3333 | 5 | yes |
| GO:0002791 | regulation of peptide secretion | 6.6667 | 6 | yes |
| GO:0019229 | regulation of vasoconstriction | 6.6667 | 6 | yes |
| GO:0035150 | regulation of tube size | 6.6667 | 4 | yes |
| GO:0035296 | regulation of tube diameter | 6.6667 | 5 | yes |
| GO:0045907 | positive regulation of vasoconstriction | 6.6667 | 5 | yes |
| GO:0046883 | regulation of hormone secretion | 6.6667 | 4 | yes |
| GO:0046887 | positive regulation of hormone secretion | 6.6667 | 5 | yes |
| GO:0050714 | positive regulation of protein secretion | 6.6667 | 6 | yes |
| GO:0061041 | regulation of wound healing | 6.6667 | 6 | yes |
| GO:0071345 | cellular response to cytokine stimulus | 6.6667 | 5 | yes |
| GO:0090087 | regulation of peptide transport | 6.6667 | 5 | yes |
| GO:0090276 | regulation of peptide hormone secretion | 6.6667 | 5 | yes |
| GO:0097746 | blood vessel diameter maintenance | 6.6667 | 5 | yes |
| GO:1900024 | regulation of substrate adhesion-dependent cell spreading | 6.6667 | 6 | yes |
| GO:1900026 | positive regulation of substrate adhesion-dependent cell spreading | 6.6667 | 7 | yes |
| GO:1904035 | regulation of epithelial cell apoptotic process | 6.6667 | 7 | yes |
| GO:2000351 | regulation of endothelial cell apoptotic process | 6.6667 | 8 | yes |
| GO:2001234 | negative regulation of apoptotic signaling pathway | 6.6667 | 6 | yes |
| GO:2001236 | regulation of extrinsic apoptotic signaling pathway | 6.6667 | 6 | yes |
| GO:0002793 | positive regulation of peptide secretion | 5.0000 | 6 | yes |
| GO:0016485 | protein processing | 5.0000 | 5 | yes |
| GO:0017157 | regulation of exocytosis | 5.0000 | 5 | yes |
| GO:0019730 | antimicrobial humoral response | 5.0000 | 4 | yes |
| GO:0019731 | antibacterial humoral response | 5.0000 | 5 | yes |
| GO:0030193 | regulation of blood coagulation | 5.0000 | 4 | yes |
| GO:0030195 | negative regulation of blood coagulation | 5.0000 | 5 | yes |
| GO:0031638 | zymogen activation | 5.0000 | 6 | yes |
| GO:0031639 | plasminogen activation | 5.0000 | 7 | yes |
| GO:0034114 | regulation of heterotypic cell-cell adhesion | 5.0000 | 6 | yes |
| GO:0034116 | positive regulation of heterotypic cell-cell adhesion | 5.0000 | 7 | yes |
| GO:0042730 | fibrinolysis | 5.0000 | 6 | yes |
| GO:0042742 | defense response to bacterium | 5.0000 | 4 | yes |
| GO:0045921 | positive regulation of exocytosis | 5.0000 | 6 | yes |
| GO:0050818 | regulation of coagulation | 5.0000 | 4 | yes |
| GO:0050819 | negative regulation of coagulation | 5.0000 | 5 | yes |
| GO:0051258 | protein polymerization | 5.0000 | 6 | yes |
| GO:0051604 | protein maturation | 5.0000 | 4 | yes |
| GO:0061045 | negative regulation of wound healing | 5.0000 | 6 | yes |
| GO:0071347 | cellular response to interleukin-1 | 5.0000 | 6 | yes |
| GO:0072376 | protein activation cascade | 5.0000 | 5 | yes |
| GO:0072378 | blood coagulation, fibrin clot formation | 5.0000 | 6 | yes |
| GO:0090277 | positive regulation of peptide hormone secretion | 5.0000 | 6 | yes |
| GO:1900047 | negative regulation of hemostasis | 5.0000 | 4 | yes |
| GO:1902041 | regulation of extrinsic apoptotic signaling pathway via death domain receptors | 5.0000 | 7 | yes |
| GO:1902042 | negative regulation of extrinsic apoptotic signaling pathway via death domain receptors | 5.0000 | 8 | yes |
| GO:1903035 | negative regulation of response to wounding | 5.0000 | 5 | yes |
| GO:1904036 | negative regulation of epithelial cell apoptotic process | 5.0000 | 8 | yes |
| GO:2000352 | negative regulation of endothelial cell apoptotic process | 5.0000 | 9 | yes |
| GO:2001237 | negative regulation of extrinsic apoptotic signaling pathway | 5.0000 | 7 | yes |
| GO:0043152 | induction of bacterial agglutination | 3.3333 | 6 | yes |
| GO:0044320 | cellular response to leptin stimulus | 3.3333 | 5 | yes |
| GO:0044321 | response to leptin | 3.3333 | 4 | yes |
Disease
| Term | Name | % | Distance from top the of the tree | Annotated in FIBB_HUMAN |
|---|---|---|---|---|
| DOID:331 | central nervous system disease | 3.3333 | 3 | no |
All partners
| Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
|---|---|---|---|---|
| FIBA_HUMAN | [view interactions] | Low throughput | no | no |
| CALR_HUMAN | [view interactions] | Low throughput | no | yes |
| LRP1B_HUMAN | [view interactions] | Low throughput | no | yes |
| NID1_HUMAN | [view interactions] | Low throughput | no | no |
| FBLN1_HUMAN | [view interactions] | Low throughput | no | yes |
| A4_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| FIBG_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| THRB_HUMAN | [view interactions] | Low throughput | no | no |
| DRA_HUMAN | [view interactions] | Low throughput | no | no |
| FIBB_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| DRB1_HUMAN | [view interactions] | Low throughput | no | no |
| CDN1A_HUMAN | [view interactions] | High throughput | no | no |
| GRB7_HUMAN | [view interactions] | High throughput | no | no |
| AIMP2_HUMAN | [view interactions] | High throughput | no | yes |
| P55G_HUMAN | [view interactions] | High throughput | no | yes |
| SMN_HUMAN | [view interactions] | High throughput | no | yes |
| KITH_HUMAN | [view interactions] | High throughput | no | yes |
| LZIC_HUMAN | [view interactions] | High throughput | no | no |
| SPRE_HUMAN | [view interactions] | High throughput | no | yes |
| PIR_HUMAN | [view interactions] | High throughput | no | no |
| TLN1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| SBDS_HUMAN | [view interactions] | High throughput | no | yes |
| CAB39_HUMAN | [view interactions] | High throughput | no | yes |
| RRP44_HUMAN | [view interactions] | High throughput | no | yes |
| SNX6_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| PSME2_HUMAN | [view interactions] | High throughput | no | no |
| PNPO_HUMAN | [view interactions] | High throughput | no | yes |
| RBM12_HUMAN | [view interactions] | High throughput | no | yes |
| SYFB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RPR1B_HUMAN | [view interactions] | High throughput | no | yes |
| UBE2T_HUMAN | [view interactions] | High throughput | no | no |
| ARMT1_HUMAN | [view interactions] | High throughput | no | yes |
| NAA50_HUMAN | [view interactions] | High throughput | no | yes |
| FTO_HUMAN | [view interactions] | High throughput | no | yes |
| EIF2A_HUMAN | [view interactions] | High throughput | no | yes |
| ITPA_HUMAN | [view interactions] | High throughput | no | yes |
| NAA15_HUMAN | [view interactions] | High throughput | no | yes |
| VRK1_HUMAN | [view interactions] | High throughput | no | yes |
| PUS7_HUMAN | [view interactions] | High throughput | no | yes |
| RPR1A_HUMAN | [view interactions] | High throughput | no | yes |
| TOPK_HUMAN | [view interactions] | High throughput | no | no |
| OTUB1_HUMAN | [view interactions] | High throughput | no | yes |
| K1143_HUMAN | [view interactions] | High throughput | no | yes |
| SYAP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GPKOW_HUMAN | [view interactions] | High throughput | no | yes |
| UBCP1_HUMAN | [view interactions] | High throughput | no | yes |
| HS904_HUMAN | [view interactions] | High throughput | no | no |
| SF3A1_HUMAN | [view interactions] | High throughput | no | yes |
| PMVK_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PAK2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| SCRN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PPID_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RHG01_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| EF1A2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HMCS1_HUMAN | [view interactions] | High throughput | no | yes |
| VIGLN_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ERF1_HUMAN | [view interactions] | High throughput | no | yes |
| RHOA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DUS3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| PAPOA_HUMAN | [view interactions] | High throughput | no | yes |
| GNAQ_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KPCI_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FEN1_HUMAN | [view interactions] | High throughput | no | yes |
| GNL1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| T2FA_HUMAN | [view interactions] | High throughput | no | yes |
| PUR8_HUMAN | [view interactions] | High throughput | no | yes |
| BLVRB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GRAN_HUMAN | [view interactions] | High throughput | no | no |
| TCEA1_HUMAN | [view interactions] | High throughput | no | no |
| UBA1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PYGB_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| OXSR1_HUMAN | [view interactions] | High throughput | no | yes |
| LETM1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DDAH1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| EIF3J_HUMAN | [view interactions] | High throughput | no | yes |
| VP26A_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| SNX3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| NDK8_HUMAN | [view interactions] | High throughput | no | no |
| SYNC_HUMAN | [view interactions] | High throughput | no | yes |
| DENR_HUMAN | [view interactions] | High throughput | no | yes |
| PAPS1_HUMAN | [view interactions] | High throughput | no | yes |
| LSM1_HUMAN | [view interactions] | High throughput | no | no |
| KIF2A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ALDH2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| MK06_HUMAN | [view interactions] | High throughput | no | yes |
| H2B1J_HUMAN | [view interactions] | High throughput | no | yes |
| 1433T_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| C1QBP_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RL1D1_HUMAN | [view interactions] | High throughput | no | yes |
| CFTR_HUMAN | [view interactions] | High throughput | no | no |
| GCR_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KCMA1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CAV3_HUMAN | [view interactions] | High throughput | no | no |
| RYR2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| INSR_HUMAN | [view interactions] | High throughput | no | yes |
| F13B_HUMAN | [view interactions] | High throughput | no | no |
| KLK6_HUMAN | [view interactions] | High throughput | no | no |
| MIS12_HUMAN | [view interactions] | High throughput | no | yes |
| NSD2_HUMAN | [view interactions] | High throughput | no | yes |
| UFL1_HUMAN | [view interactions] | High throughput | no | yes |
| KHDR2_HUMAN | [view interactions] | High throughput | no | yes |
| FINC_HUMAN | [view interactions] | High throughput | no | yes |
| ASB6_HUMAN | [view interactions] | High throughput | no | yes |
| ASB7_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ASCC1_HUMAN | [view interactions] | High throughput | no | yes |
| DD19B_HUMAN | [view interactions] | High throughput | no | yes |
| TM237_HUMAN | [view interactions] | High throughput | no | no |
| SNX27_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ADK_HUMAN | [view interactions] | High throughput | no | yes |
| RING1_HUMAN | [view interactions] | High throughput | no | yes |
| NDKB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PO2F1_HUMAN | [view interactions] | High throughput | no | yes |
| SLK_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CTBL1_HUMAN | [view interactions] | High throughput | no | yes |
| TBC24_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MP2K1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ATG3_HUMAN | [view interactions] | High throughput | no | yes |
| CCYL1_HUMAN | [view interactions] | High throughput | no | yes |
| MCTS1_HUMAN | [view interactions] | High throughput | no | no |
| PYM1_HUMAN | [view interactions] | High throughput | no | yes |
| CGL_HUMAN | [view interactions] | High throughput | no | yes |
| HDGR2_HUMAN | [view interactions] | High throughput | no | yes |
| USO1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PTN11_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TES_HUMAN | [view interactions] | High throughput | no | yes |
| PAK1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GLSK_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FACD2_HUMAN | [view interactions] | High throughput | no | no |
| LAP2A_HUMAN | [view interactions] | High throughput | no | yes |
| ESR2_HUMAN | [view interactions] | High throughput | no | no |
| TET2_HUMAN | [view interactions] | High throughput | no | yes |
| SP110_HUMAN | [view interactions] | High throughput | no | no |
| HPT_HUMAN | [view interactions] | High throughput | no | no |
| TRFE_HUMAN | [view interactions] | High throughput | no | no |
| VTDB_HUMAN | [view interactions] | High throughput | no | yes |
| CERU_HUMAN | [view interactions] | High throughput | no | no |
| AACT_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CLUS_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HEMO_HUMAN | [view interactions] | High throughput | no | no |
| A1AG1_HUMAN | [view interactions] | High throughput | no | no |
| PROL4_HUMAN | [view interactions] | High throughput | no | no |
| A1AT_HUMAN | [view interactions] | High throughput | no | no |
| STAT_HUMAN | [view interactions] | High throughput | no | no |
| TRI37_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SIA7F_HUMAN | [view interactions] | High throughput | no | yes |
| BT3L4_HUMAN | [view interactions] | High throughput | no | yes |
| CHRD1_HUMAN | [view interactions] | High throughput | no | yes |
| ATPF2_HUMAN | [view interactions] | High throughput | no | yes |
| 2ABB_HUMAN | [view interactions] | High throughput | no | yes |
| FNDC1_HUMAN | [view interactions] | High throughput | no | yes |
| MINY3_HUMAN | [view interactions] | High throughput | no | yes |
| TBCE_HUMAN | [view interactions] | High throughput | no | no |
| XPP1_HUMAN | [view interactions] | High throughput | no | yes |
| CHM1A_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CRDL2_HUMAN | [view interactions] | High throughput | no | yes |
| HPF1_HUMAN | [view interactions] | High throughput | no | no |
| DBNL_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DSCR6_HUMAN | [view interactions] | High throughput | no | no |
| GBG8_HUMAN | [view interactions] | High throughput | no | no |
| STX17_HUMAN | [view interactions] | High throughput | no | yes |
| DDX1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SAR1B_HUMAN | [view interactions] | High throughput | no | yes |
| AATC_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GLRX3_HUMAN | [view interactions] | High throughput | no | yes |
| ARFG1_HUMAN | [view interactions] | High throughput | no | no |
| ICAL_HUMAN | [view interactions] | High throughput | no | yes |
| SC6A1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| SARAF_HUMAN | [view interactions] | High throughput | no | no |
| SG1D1_HUMAN | [view interactions] | High throughput | no | no |
| UBE2U_HUMAN | [view interactions] | High throughput | no | no |
| PHF11_HUMAN | [view interactions] | High throughput | no | no |
| SL9A5_HUMAN | [view interactions] | High throughput | no | no |
| CIR1_HUMAN | [view interactions] | High throughput | no | yes |
| ADT3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CCR1_HUMAN | [view interactions] | High throughput | no | no |
| PINK1_HUMAN | [view interactions] | High throughput | no | yes |
| PIGT_HUMAN | [view interactions] | High throughput | no | no |
| PDE6D_HUMAN | [view interactions] | High throughput | no | yes |
| LEG3_HUMAN | [view interactions] | High throughput | no | yes |
| CERS3_HUMAN | [view interactions] | High throughput | no | no |
| SSUH2_HUMAN | [view interactions] | High throughput | no | no |
| P2RX6_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| EGFL8_HUMAN | [view interactions] | High throughput | no | no |
| SSBP2_HUMAN | [view interactions] | High throughput | no | yes |
| CR021_HUMAN | [view interactions] | High throughput | no | no |
| PLCA_HUMAN | [view interactions] | High throughput | no | yes |
| RHBL4_HUMAN | [view interactions] | High throughput | no | no |
| MBNL1_HUMAN | [view interactions] | High throughput | no | yes |
| KLK10_HUMAN | [view interactions] | High throughput | no | no |
| CP343_HUMAN | [view interactions] | High throughput | no | no |
| CSK_HUMAN | [view interactions] | High throughput | no | yes |
| KNG1_HUMAN | [view interactions] | High throughput | no | no |
| PLMN_HUMAN | [view interactions] | High throughput | no | no |
| ANT3_HUMAN | [view interactions] | High throughput | no | no |
| CSK2B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ANXA7_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HAOX1_HUMAN | [view interactions] | Computational | no | no |
| APOA_HUMAN | [view interactions] | Computational | no | no |
| PEBP1_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| CO8A_HUMAN | [view interactions] | Computational | no | no |
| HRG_HUMAN | [view interactions] | Computational | no | no |
| ITA2B_HUMAN | [view interactions] | Computational | no | no |
| A2AP_HUMAN | [view interactions] | Computational | no | no |
| PTN1_HUMAN | [view interactions] | Computational | no | yes |
| ITB3_HUMAN | [view entry] [view interactions] | Computational | yes | no |
| ITAM_HUMAN | [view interactions] | Computational | no | no |
| HABP2_HUMAN | [view interactions] | Computational | no | no |
| FGL1_HUMAN | [view interactions] | Computational | no | no |
| ITB2_HUMAN | [view interactions] | Computational | no | no |
| TSP1_HUMAN | [view interactions] | Computational | no | no |
| APOA1_HUMAN | [view interactions] | Computational | no | no |
| APOM_HUMAN | [view interactions] | Computational | no | no |
| APOA4_HUMAN | [view interactions] | Computational | no | no |
| APOH_HUMAN | [view interactions] | Computational | no | no |
| IPSP_HUMAN | [view interactions] | Computational | no | no |
| ITA5_HUMAN | [view entry] [view interactions] | Computational | yes | no |
| FETUB_HUMAN | [view interactions] | Computational | no | no |
| AMBP_HUMAN | [view interactions] | Computational | no | no |
| ITB1_HUMAN | [view entry] [view interactions] | Computational | yes | no |
| UPAR_HUMAN | [view interactions] | Computational | no | yes |
| CO9_HUMAN | [view interactions] | Computational | no | no |
| PROC_HUMAN | [view interactions] | Computational | no | no |
| UROK_HUMAN | [view interactions] | Computational | no | no |
| HEP2_HUMAN | [view interactions] | Computational | no | no |
| FTCD_HUMAN | [view interactions] | Computational | no | no |
| ITAV_HUMAN | [view interactions] | Computational | no | yes |