FIBB_HUMAN
Evidence for PS localization
Functions
Cleaved by the protease thrombin to yield monomers which, together with fibrinogen alpha (FGA) and fibrinogen gamma (FGG), polymerize to form an insoluble fibrin matrix. Fibrin has a major function in hemostasis as one of the primary components of blood clots. In addition, functions during the early stages of wound repair to stabilize the lesion and guide cell migration during re-epithelialization. Was originally thought to be essential for platelet aggregation, based on in vitro studies using anticoagulated blood. However subsequent studies have shown that it is not absolutely required for thrombus formation in vivo. Enhances expression of SELP in activated platelets. Maternal fibrinogen is essential for successful pregnancy. Fibrin deposition is also associated with infection, where it protects against IFNG-mediated hemorrhage. May also facilitate the antibacterial immune response via both innate and T-cell mediated pathways. [View more on UniProt]
Protein features
Binary interactions with known binding regions
To display all evidence describing the interaction with a partner, click on the protein name left to the bars.
Network
Isoforms
Disease-causing germline mutations
No data found.
Linear motifs
No annotated instance was found. To search for linear motifs, use the ELM prediction server.
Fingerprint
Molecular function
| Term | Name | % | Distance from the top of the tree | Annotated in FIBB_HUMAN |
|---|---|---|---|---|
| GO:0043168 | anion binding | 33.8983 | 4 | no |
| GO:0043169 | cation binding | 30.5085 | 4 | no |
| GO:0046872 | metal ion binding | 30.5085 | 5 | no |
| GO:0000166 | nucleotide binding | 28.8136 | 4 | no |
| GO:0017076 | purine nucleotide binding | 28.8136 | 5 | no |
| GO:0032555 | purine ribonucleotide binding | 27.1186 | 4 | no |
| GO:0035639 | purine ribonucleoside triphosphate binding | 27.1186 | 4 | no |
| GO:0030554 | adenyl nucleotide binding | 22.0339 | 6 | no |
| GO:0005524 | ATP binding | 20.3390 | 5 | no |
| GO:0032559 | adenyl ribonucleotide binding | 20.3390 | 5 | no |
Biological process
| Term | Name | % | Distance from top the of the tree | Annotated in FIBB_HUMAN |
|---|---|---|---|---|
| GO:0048523 | negative regulation of cellular process | 55.9322 | 4 | yes |
| GO:0010646 | regulation of cell communication | 44.0678 | 4 | yes |
| GO:0048522 | positive regulation of cellular process | 44.0678 | 4 | yes |
| GO:0060255 | regulation of macromolecule metabolic process | 42.3729 | 4 | no |
| GO:0080090 | regulation of primary metabolic process | 42.3729 | 4 | no |
| GO:0031323 | regulation of cellular metabolic process | 40.6780 | 4 | no |
| GO:0009966 | regulation of signal transduction | 38.9831 | 4 | yes |
| GO:0022607 | cellular component assembly | 35.5932 | 4 | yes |
| GO:0009889 | regulation of biosynthetic process | 33.8983 | 4 | no |
| GO:0051128 | regulation of cellular component organization | 32.2034 | 4 | no |
| GO:0043933 | protein-containing complex organization | 32.2034 | 4 | yes |
| GO:0006996 | organelle organization | 30.5085 | 4 | no |
| GO:0008104 | protein localization | 30.5085 | 4 | no |
| GO:0010468 | regulation of gene expression | 30.5085 | 6 | no |
| GO:0010556 | regulation of macromolecule biosynthetic process | 30.5085 | 5 | no |
| GO:0031326 | regulation of cellular biosynthetic process | 30.5085 | 5 | no |
| GO:0009892 | negative regulation of metabolic process | 30.5085 | 4 | no |
| GO:0042981 | regulation of apoptotic process | 30.5085 | 5 | yes |
| GO:0043067 | regulation of programmed cell death | 30.5085 | 4 | yes |
| GO:0051049 | regulation of transport | 30.5085 | 4 | yes |
| GO:1902531 | regulation of intracellular signal transduction | 28.8136 | 5 | yes |
| GO:0051246 | regulation of protein metabolic process | 28.8136 | 5 | no |
| GO:0010605 | negative regulation of macromolecule metabolic process | 28.8136 | 5 | no |
| GO:0009893 | positive regulation of metabolic process | 27.1186 | 4 | no |
| GO:0009967 | positive regulation of signal transduction | 27.1186 | 5 | yes |
| GO:0010647 | positive regulation of cell communication | 27.1186 | 5 | yes |
| GO:0023056 | positive regulation of signaling | 27.1186 | 4 | yes |
| GO:0048584 | positive regulation of response to stimulus | 27.1186 | 4 | yes |
| GO:0031325 | positive regulation of cellular metabolic process | 25.4237 | 5 | no |
| GO:0031324 | negative regulation of cellular metabolic process | 25.4237 | 5 | no |
| GO:0071702 | organic substance transport | 25.4237 | 4 | no |
| GO:0051240 | positive regulation of multicellular organismal process | 25.4237 | 4 | yes |
| GO:0065003 | protein-containing complex assembly | 23.7288 | 5 | yes |
| GO:0071310 | cellular response to organic substance | 23.7288 | 4 | yes |
| GO:0010604 | positive regulation of macromolecule metabolic process | 23.7288 | 5 | no |
| GO:0006355 | regulation of DNA-templated transcription | 23.7288 | 7 | no |
| GO:0019219 | regulation of nucleobase-containing compound metabolic process | 23.7288 | 5 | no |
| GO:0051252 | regulation of RNA metabolic process | 23.7288 | 5 | no |
| GO:2001141 | regulation of RNA biosynthetic process | 23.7288 | 6 | no |
| GO:0071705 | nitrogen compound transport | 23.7288 | 4 | no |
| GO:0080134 | regulation of response to stress | 22.0339 | 4 | yes |
| GO:1902533 | positive regulation of intracellular signal transduction | 22.0339 | 6 | yes |
| GO:0036211 | protein modification process | 22.0339 | 4 | no |
| GO:0043412 | macromolecule modification | 22.0339 | 4 | no |
| GO:0009890 | negative regulation of biosynthetic process | 22.0339 | 5 | no |
| GO:0010648 | negative regulation of cell communication | 22.0339 | 5 | yes |
| GO:0023057 | negative regulation of signaling | 22.0339 | 4 | yes |
| GO:0048585 | negative regulation of response to stimulus | 22.0339 | 4 | yes |
| GO:0010558 | negative regulation of macromolecule biosynthetic process | 20.3390 | 6 | no |
| GO:0031327 | negative regulation of cellular biosynthetic process | 20.3390 | 6 | no |
| GO:0015031 | protein transport | 20.3390 | 4 | no |
| GO:0009968 | negative regulation of signal transduction | 18.6441 | 5 | yes |
| GO:0030155 | regulation of cell adhesion | 18.6441 | 4 | yes |
| GO:0032101 | regulation of response to external stimulus | 18.6441 | 4 | yes |
| GO:0043066 | negative regulation of apoptotic process | 18.6441 | 6 | yes |
| GO:0043069 | negative regulation of programmed cell death | 18.6441 | 5 | yes |
| GO:0051241 | negative regulation of multicellular organismal process | 18.6441 | 4 | yes |
| GO:0060341 | regulation of cellular localization | 16.9492 | 4 | yes |
| GO:0051050 | positive regulation of transport | 16.9492 | 4 | yes |
| GO:0060627 | regulation of vesicle-mediated transport | 15.2542 | 4 | yes |
| GO:0010810 | regulation of cell-substrate adhesion | 15.2542 | 5 | yes |
| GO:0043408 | regulation of MAPK cascade | 15.2542 | 6 | yes |
| GO:0044057 | regulation of system process | 15.2542 | 4 | yes |
| GO:0010038 | response to metal ion | 13.5593 | 4 | yes |
| GO:0032880 | regulation of protein localization | 13.5593 | 5 | yes |
| GO:0070201 | regulation of establishment of protein localization | 11.8644 | 6 | yes |
| GO:0070372 | regulation of ERK1 and ERK2 cascade | 11.8644 | 7 | yes |
| GO:0003018 | vascular process in circulatory system | 11.8644 | 4 | yes |
| GO:0022407 | regulation of cell-cell adhesion | 11.8644 | 5 | yes |
| GO:0043410 | positive regulation of MAPK cascade | 11.8644 | 7 | yes |
| GO:0045785 | positive regulation of cell adhesion | 11.8644 | 5 | yes |
| GO:0070374 | positive regulation of ERK1 and ERK2 cascade | 10.1695 | 8 | yes |
| GO:1903829 | positive regulation of protein localization | 10.1695 | 5 | yes |
| GO:2001233 | regulation of apoptotic signaling pathway | 10.1695 | 5 | yes |
| GO:0006508 | proteolysis | 10.1695 | 4 | yes |
| GO:0032870 | cellular response to hormone stimulus | 10.1695 | 4 | yes |
| GO:0034097 | response to cytokine | 10.1695 | 4 | yes |
| GO:0051046 | regulation of secretion | 10.1695 | 5 | yes |
| GO:0051047 | positive regulation of secretion | 10.1695 | 5 | yes |
| GO:0051223 | regulation of protein transport | 10.1695 | 5 | yes |
| GO:0051592 | response to calcium ion | 10.1695 | 5 | yes |
| GO:0070555 | response to interleukin-1 | 8.4746 | 5 | yes |
| GO:0097746 | blood vessel diameter maintenance | 8.4746 | 5 | yes |
| GO:0140546 | defense response to symbiont | 8.4746 | 4 | yes |
| GO:1900024 | regulation of substrate adhesion-dependent cell spreading | 8.4746 | 6 | yes |
| GO:1900026 | positive regulation of substrate adhesion-dependent cell spreading | 8.4746 | 7 | yes |
| GO:1903522 | regulation of blood circulation | 8.4746 | 5 | yes |
| GO:1903530 | regulation of secretion by cell | 8.4746 | 4 | yes |
| GO:1903532 | positive regulation of secretion by cell | 8.4746 | 5 | yes |
| GO:1904951 | positive regulation of establishment of protein localization | 8.4746 | 6 | yes |
| GO:2001234 | negative regulation of apoptotic signaling pathway | 8.4746 | 6 | yes |
| GO:0010811 | positive regulation of cell-substrate adhesion | 8.4746 | 6 | yes |
| GO:0022409 | positive regulation of cell-cell adhesion | 8.4746 | 6 | yes |
| GO:0032102 | negative regulation of response to external stimulus | 8.4746 | 5 | yes |
| GO:0035150 | regulation of tube size | 8.4746 | 4 | yes |
| GO:0035296 | regulation of tube diameter | 8.4746 | 5 | yes |
| GO:0050708 | regulation of protein secretion | 8.4746 | 5 | yes |
| GO:0070527 | platelet aggregation | 6.7797 | 5 | yes |
| GO:0071345 | cellular response to cytokine stimulus | 6.7797 | 5 | yes |
| GO:0090087 | regulation of peptide transport | 6.7797 | 5 | yes |
| GO:0090276 | regulation of peptide hormone secretion | 6.7797 | 5 | yes |
| GO:1903034 | regulation of response to wounding | 6.7797 | 5 | yes |
| GO:1904035 | regulation of epithelial cell apoptotic process | 6.7797 | 6 | yes |
| GO:2000351 | regulation of endothelial cell apoptotic process | 6.7797 | 7 | yes |
| GO:2001236 | regulation of extrinsic apoptotic signaling pathway | 6.7797 | 6 | yes |
| GO:0002791 | regulation of peptide secretion | 6.7797 | 6 | yes |
| GO:0007160 | cell-matrix adhesion | 6.7797 | 4 | yes |
| GO:0019229 | regulation of vasoconstriction | 6.7797 | 6 | yes |
| GO:0034109 | homotypic cell-cell adhesion | 6.7797 | 4 | yes |
| GO:0045907 | positive regulation of vasoconstriction | 6.7797 | 5 | yes |
| GO:0046883 | regulation of hormone secretion | 6.7797 | 4 | yes |
| GO:0046887 | positive regulation of hormone secretion | 6.7797 | 5 | yes |
| GO:0050714 | positive regulation of protein secretion | 6.7797 | 6 | yes |
| GO:0051222 | positive regulation of protein transport | 6.7797 | 5 | yes |
| GO:0051604 | protein maturation | 6.7797 | 4 | yes |
| GO:0061041 | regulation of wound healing | 5.0847 | 6 | yes |
| GO:0061045 | negative regulation of wound healing | 5.0847 | 6 | yes |
| GO:0071347 | cellular response to interleukin-1 | 5.0847 | 6 | yes |
| GO:0072376 | protein activation cascade | 5.0847 | 5 | yes |
| GO:0072378 | blood coagulation, fibrin clot formation | 5.0847 | 6 | yes |
| GO:0090277 | positive regulation of peptide hormone secretion | 5.0847 | 6 | yes |
| GO:1900047 | negative regulation of hemostasis | 5.0847 | 4 | yes |
| GO:1902041 | regulation of extrinsic apoptotic signaling pathway via death domain receptors | 5.0847 | 7 | yes |
| GO:1902042 | negative regulation of extrinsic apoptotic signaling pathway via death domain receptors | 5.0847 | 8 | yes |
| GO:1903035 | negative regulation of response to wounding | 5.0847 | 5 | yes |
| GO:1904036 | negative regulation of epithelial cell apoptotic process | 5.0847 | 7 | yes |
| GO:2000352 | negative regulation of endothelial cell apoptotic process | 5.0847 | 8 | yes |
| GO:2001237 | negative regulation of extrinsic apoptotic signaling pathway | 5.0847 | 7 | yes |
| GO:0002793 | positive regulation of peptide secretion | 5.0847 | 6 | yes |
| GO:0016485 | protein processing | 5.0847 | 5 | yes |
| GO:0017157 | regulation of exocytosis | 5.0847 | 5 | yes |
| GO:0030193 | regulation of blood coagulation | 5.0847 | 4 | yes |
| GO:0030195 | negative regulation of blood coagulation | 5.0847 | 5 | yes |
| GO:0031638 | zymogen activation | 5.0847 | 6 | yes |
| GO:0031639 | plasminogen activation | 5.0847 | 7 | yes |
| GO:0034114 | regulation of heterotypic cell-cell adhesion | 5.0847 | 6 | yes |
| GO:0034116 | positive regulation of heterotypic cell-cell adhesion | 5.0847 | 7 | yes |
| GO:0042730 | fibrinolysis | 5.0847 | 6 | yes |
| GO:0045921 | positive regulation of exocytosis | 5.0847 | 6 | yes |
| GO:0050818 | regulation of coagulation | 5.0847 | 4 | yes |
| GO:0050819 | negative regulation of coagulation | 5.0847 | 5 | yes |
| GO:0051258 | protein polymerization | 5.0847 | 6 | yes |
| GO:0019730 | antimicrobial humoral response | 3.3898 | 4 | yes |
| GO:0019731 | antibacterial humoral response | 3.3898 | 5 | yes |
| GO:0042742 | defense response to bacterium | 3.3898 | 4 | yes |
| GO:0043152 | induction of bacterial agglutination | 3.3898 | 6 | yes |
| GO:0044320 | cellular response to leptin stimulus | 3.3898 | 5 | yes |
| GO:0044321 | response to leptin | 3.3898 | 4 | yes |
Disease
No data found.
All partners
| Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
|---|---|---|---|---|
| FIBA_HUMAN | [view interactions] | Low throughput | no | no |
| CALR_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| LRP1B_HUMAN | [view interactions] | Low throughput | no | yes |
| NID1_HUMAN | [view interactions] | Low throughput | no | no |
| FBLN1_HUMAN | [view interactions] | Low throughput | no | yes |
| A4_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| VWF_HUMAN | [view interactions] | Low throughput | no | no |
| FIBG_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| FIBB_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| THRB_HUMAN | [view interactions] | Low throughput | no | no |
| DRA_HUMAN | [view interactions] | Low throughput | no | no |
| DRB1_HUMAN | [view interactions] | Low throughput | no | no |
| VRK1_HUMAN | [view interactions] | High throughput | no | yes |
| NAA15_HUMAN | [view interactions] | High throughput | no | yes |
| ITPA_HUMAN | [view interactions] | High throughput | no | yes |
| EIF2A_HUMAN | [view interactions] | High throughput | no | yes |
| FTO_HUMAN | [view interactions] | High throughput | no | yes |
| NAA50_HUMAN | [view interactions] | High throughput | no | yes |
| ARMT1_HUMAN | [view interactions] | High throughput | no | yes |
| UBE2T_HUMAN | [view interactions] | High throughput | no | no |
| RPR1B_HUMAN | [view interactions] | High throughput | no | yes |
| SYFB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RBM12_HUMAN | [view interactions] | High throughput | no | yes |
| PNPO_HUMAN | [view interactions] | High throughput | no | yes |
| PSME2_HUMAN | [view interactions] | High throughput | no | no |
| SNX6_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RRP44_HUMAN | [view interactions] | High throughput | no | yes |
| CAB39_HUMAN | [view interactions] | High throughput | no | yes |
| SBDS_HUMAN | [view interactions] | High throughput | no | yes |
| TLN1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ALDH2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| MK06_HUMAN | [view interactions] | High throughput | no | yes |
| H2B1J_HUMAN | [view interactions] | High throughput | no | yes |
| 1433T_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| C1QBP_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RL1D1_HUMAN | [view interactions] | High throughput | no | yes |
| CFTR_HUMAN | [view interactions] | High throughput | no | no |
| GCR_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KCMA1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CAV3_HUMAN | [view interactions] | High throughput | no | no |
| RYR2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| INSR_HUMAN | [view interactions] | High throughput | no | yes |
| F13B_HUMAN | [view interactions] | High throughput | no | no |
| KLK6_HUMAN | [view interactions] | High throughput | no | no |
| MIS12_HUMAN | [view interactions] | High throughput | no | yes |
| NSD2_HUMAN | [view interactions] | High throughput | no | yes |
| UFL1_HUMAN | [view interactions] | High throughput | no | yes |
| RN181_HUMAN | [view interactions] | High throughput | no | no |
| KHDR2_HUMAN | [view interactions] | High throughput | no | yes |
| FINC_HUMAN | [view interactions] | High throughput | no | yes |
| ASB6_HUMAN | [view interactions] | High throughput | no | yes |
| ASB7_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ASCC1_HUMAN | [view interactions] | High throughput | no | yes |
| DD19B_HUMAN | [view interactions] | High throughput | no | yes |
| TM237_HUMAN | [view interactions] | High throughput | no | no |
| SNX27_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ADK_HUMAN | [view interactions] | High throughput | no | yes |
| RING1_HUMAN | [view interactions] | High throughput | no | yes |
| NDKB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PO2F1_HUMAN | [view interactions] | High throughput | no | yes |
| SLK_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CTBL1_HUMAN | [view interactions] | High throughput | no | yes |
| TBC24_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MP2K1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ATG3_HUMAN | [view interactions] | High throughput | no | yes |
| CCYL1_HUMAN | [view interactions] | High throughput | no | yes |
| MCTS1_HUMAN | [view interactions] | High throughput | no | no |
| PYM1_HUMAN | [view interactions] | High throughput | no | yes |
| CGL_HUMAN | [view interactions] | High throughput | no | yes |
| HDGR2_HUMAN | [view interactions] | High throughput | no | yes |
| USO1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PTN11_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TES_HUMAN | [view interactions] | High throughput | no | yes |
| PAK1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GLSK_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FACD2_HUMAN | [view interactions] | High throughput | no | no |
| LAP2A_HUMAN | [view interactions] | High throughput | no | yes |
| ESR2_HUMAN | [view interactions] | High throughput | no | no |
| TET2_HUMAN | [view interactions] | High throughput | no | yes |
| SP110_HUMAN | [view interactions] | High throughput | no | no |
| HPT_HUMAN | [view interactions] | High throughput | no | no |
| TRFE_HUMAN | [view interactions] | High throughput | no | no |
| VTDB_HUMAN | [view interactions] | High throughput | no | yes |
| CERU_HUMAN | [view interactions] | High throughput | no | no |
| AACT_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CLUS_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HEMO_HUMAN | [view interactions] | High throughput | no | no |
| A1AG1_HUMAN | [view interactions] | High throughput | no | no |
| PROL4_HUMAN | [view interactions] | High throughput | no | no |
| A1AT_HUMAN | [view interactions] | High throughput | no | no |
| STAT_HUMAN | [view interactions] | High throughput | no | no |
| TRI37_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SIA7F_HUMAN | [view interactions] | High throughput | no | yes |
| BT3L4_HUMAN | [view interactions] | High throughput | no | yes |
| CHRD1_HUMAN | [view interactions] | High throughput | no | yes |
| ATPF2_HUMAN | [view interactions] | High throughput | no | yes |
| 2ABB_HUMAN | [view interactions] | High throughput | no | yes |
| FNDC1_HUMAN | [view interactions] | High throughput | no | yes |
| MINY3_HUMAN | [view interactions] | High throughput | no | yes |
| TBCE_HUMAN | [view interactions] | High throughput | no | no |
| XPP1_HUMAN | [view interactions] | High throughput | no | yes |
| CHM1A_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CRDL2_HUMAN | [view interactions] | High throughput | no | yes |
| HPF1_HUMAN | [view interactions] | High throughput | no | no |
| DBNL_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DSCR6_HUMAN | [view interactions] | High throughput | no | no |
| GBG8_HUMAN | [view interactions] | High throughput | no | no |
| STX17_HUMAN | [view interactions] | High throughput | no | yes |
| DDX1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SAR1B_HUMAN | [view interactions] | High throughput | no | yes |
| AATC_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GLRX3_HUMAN | [view interactions] | High throughput | no | yes |
| ARFG1_HUMAN | [view interactions] | High throughput | no | no |
| ICAL_HUMAN | [view interactions] | High throughput | no | yes |
| SC6A1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| SARAF_HUMAN | [view interactions] | High throughput | no | no |
| SG1D1_HUMAN | [view interactions] | High throughput | no | no |
| UBE2U_HUMAN | [view interactions] | High throughput | no | no |
| PHF11_HUMAN | [view interactions] | High throughput | no | no |
| SL9A5_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CIR1_HUMAN | [view interactions] | High throughput | no | yes |
| ADT3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CCR1_HUMAN | [view interactions] | High throughput | no | no |
| PINK1_HUMAN | [view interactions] | High throughput | no | yes |
| PIGT_HUMAN | [view interactions] | High throughput | no | no |
| PDE6D_HUMAN | [view interactions] | High throughput | no | yes |
| LEG3_HUMAN | [view interactions] | High throughput | no | yes |
| CERS3_HUMAN | [view interactions] | High throughput | no | no |
| SSUH2_HUMAN | [view interactions] | High throughput | no | no |
| P2RX6_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| EGFL8_HUMAN | [view interactions] | High throughput | no | no |
| SSBP2_HUMAN | [view interactions] | High throughput | no | yes |
| CR021_HUMAN | [view interactions] | High throughput | no | no |
| PLCA_HUMAN | [view interactions] | High throughput | no | yes |
| RHBL4_HUMAN | [view interactions] | High throughput | no | no |
| MBNL1_HUMAN | [view interactions] | High throughput | no | yes |
| KLK10_HUMAN | [view interactions] | High throughput | no | no |
| CP343_HUMAN | [view interactions] | High throughput | no | no |
| SOX2_HUMAN | [view interactions] | High throughput | no | yes |
| TRI31_HUMAN | [view interactions] | High throughput | no | no |
| ZRAN1_HUMAN | [view interactions] | High throughput | no | yes |
| PRIO_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CSK_HUMAN | [view interactions] | High throughput | no | yes |
| KNG1_HUMAN | [view interactions] | High throughput | no | no |
| PLMN_HUMAN | [view interactions] | High throughput | no | no |
| ANT3_HUMAN | [view interactions] | High throughput | no | no |
| FOXO1_HUMAN | [view interactions] | High throughput | no | yes |
| CSK2B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ANXA7_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CDN1A_HUMAN | [view interactions] | High throughput | no | no |
| GRB7_HUMAN | [view interactions] | High throughput | no | no |
| AIMP2_HUMAN | [view interactions] | High throughput | no | yes |
| P55G_HUMAN | [view interactions] | High throughput | no | yes |
| SMN_HUMAN | [view interactions] | High throughput | no | yes |
| KITH_HUMAN | [view interactions] | High throughput | no | yes |
| KIF2A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PIR_HUMAN | [view interactions] | High throughput | no | no |
| LSM1_HUMAN | [view interactions] | High throughput | no | no |
| PAPS1_HUMAN | [view interactions] | High throughput | no | yes |
| DENR_HUMAN | [view interactions] | High throughput | no | yes |
| SYNC_HUMAN | [view interactions] | High throughput | no | yes |
| NDK8_HUMAN | [view interactions] | High throughput | no | no |
| SNX3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| VP26A_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| EIF3J_HUMAN | [view interactions] | High throughput | no | yes |
| DDAH1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| LETM1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| OXSR1_HUMAN | [view interactions] | High throughput | no | yes |
| PYGB_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| UBA1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TCEA1_HUMAN | [view interactions] | High throughput | no | no |
| GRAN_HUMAN | [view interactions] | High throughput | no | no |
| BLVRB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PUR8_HUMAN | [view interactions] | High throughput | no | yes |
| T2FA_HUMAN | [view interactions] | High throughput | no | yes |
| SPRE_HUMAN | [view interactions] | High throughput | no | yes |
| GNL1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FEN1_HUMAN | [view interactions] | High throughput | no | yes |
| KPCI_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GNAQ_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PAPOA_HUMAN | [view interactions] | High throughput | no | yes |
| DUS3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RHOA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ERF1_HUMAN | [view interactions] | High throughput | no | yes |
| VIGLN_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HMCS1_HUMAN | [view interactions] | High throughput | no | yes |
| EF1A2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RHG01_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PPID_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SCRN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PAK2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| PMVK_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SF3A1_HUMAN | [view interactions] | High throughput | no | yes |
| HS904_HUMAN | [view interactions] | High throughput | no | no |
| UBCP1_HUMAN | [view interactions] | High throughput | no | yes |
| LZIC_HUMAN | [view interactions] | High throughput | no | no |
| GPKOW_HUMAN | [view interactions] | High throughput | no | yes |
| SYAP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| K1143_HUMAN | [view interactions] | High throughput | no | yes |
| OTUB1_HUMAN | [view interactions] | High throughput | no | yes |
| TOPK_HUMAN | [view interactions] | High throughput | no | no |
| RPR1A_HUMAN | [view interactions] | High throughput | no | yes |
| PUS7_HUMAN | [view interactions] | High throughput | no | yes |