NDKB_HUMAN
Evidence for PS localization
Functions
Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate . Negatively regulates Rho activity by interacting with AKAP13/LBC (PubMed). Acts as a transcriptional activator of the MYC gene; binds DNA non-specifically (PubMed, PubMed). Binds to both single-stranded guanine- and cytosine-rich strands within the nuclease hypersensitive element (NHE) III(1) region of the MYC gene promoter. Does not bind to duplex NHE III(1) (PubMed). Has G-quadruplex (G4) DNA-binding activity, which is independent of its nucleotide-binding and kinase activity. Binds both folded and unfolded G4 with similar low nanomolar affinities. Stabilizes folded G4s regardless of whether they are prefolded or not (PubMed). Exhibits histidine protein kinase activity (PubMed). [View more on UniProt]
Protein features
Binary interactions with known binding regions
To display all evidence describing the interaction with a partner, click on the protein name left to the bars.
Network
Isoforms
Disease-causing germline mutations
No data found.
Linear motifs
No annotated instance was found. To search for linear motifs, use the ELM prediction server.
Fingerprint
Molecular function
| Term | Name | % | Distance from the top of the tree | Annotated in NDKB_HUMAN |
|---|---|---|---|---|
| GO:0017076 | purine nucleotide binding | 27.9279 | 4 | yes |
| GO:0003723 | RNA binding | 27.9279 | 4 | no |
| GO:0032555 | purine ribonucleotide binding | 26.1261 | 4 | yes |
| GO:0035639 | purine ribonucleoside triphosphate binding | 26.1261 | 4 | yes |
| GO:0030554 | adenyl nucleotide binding | 21.6216 | 5 | yes |
| GO:0005524 | ATP binding | 19.8198 | 5 | yes |
| GO:0032559 | adenyl ribonucleotide binding | 19.8198 | 5 | yes |
| GO:0046872 | metal ion binding | 18.9189 | 4 | yes |
| GO:0019001 | guanyl nucleotide binding | 9.9099 | 5 | yes |
| GO:0032561 | guanyl ribonucleotide binding | 9.9099 | 5 | yes |
| GO:0003677 | DNA binding | 9.0090 | 4 | yes |
| GO:0016301 | kinase activity | 8.1081 | 4 | yes |
| GO:0016776 | phosphotransferase activity, phosphate group as acceptor | 5.4054 | 4 | yes |
| GO:0019205 | nucleobase-containing compound kinase activity | 5.4054 | 5 | yes |
| GO:0016773 | phosphotransferase activity, alcohol group as acceptor | 4.5045 | 4 | yes |
| GO:0004550 | nucleoside diphosphate kinase activity | 3.6036 | 5 | yes |
| GO:0019003 | GDP binding | 3.6036 | 4 | yes |
| GO:0004673 | protein histidine kinase activity | 1.8018 | 4 | yes |
| GO:0016775 | phosphotransferase activity, nitrogenous group as acceptor | 1.8018 | 4 | yes |
| GO:0051880 | G-quadruplex DNA binding | 1.8018 | 5 | yes |
Biological process
| Term | Name | % | Distance from top the of the tree | Annotated in NDKB_HUMAN |
|---|---|---|---|---|
| GO:0048522 | positive regulation of cellular process | 49.5495 | 4 | yes |
| GO:0048523 | negative regulation of cellular process | 45.0450 | 4 | yes |
| GO:0051171 | regulation of nitrogen compound metabolic process | 40.5405 | 4 | yes |
| GO:0060255 | regulation of macromolecule metabolic process | 40.5405 | 4 | yes |
| GO:0080090 | regulation of primary metabolic process | 39.6396 | 4 | yes |
| GO:0031323 | regulation of cellular metabolic process | 37.8378 | 4 | yes |
| GO:0051128 | regulation of cellular component organization | 36.9369 | 4 | no |
| GO:0009893 | positive regulation of metabolic process | 35.1351 | 4 | yes |
| GO:0010646 | regulation of cell communication | 33.3333 | 4 | no |
| GO:0010468 | regulation of gene expression | 33.3333 | 5 | yes |
| GO:0010941 | regulation of cell death | 30.6306 | 4 | yes |
| GO:0031326 | regulation of cellular biosynthetic process | 29.7297 | 5 | yes |
| GO:0051246 | regulation of protein metabolic process | 29.7297 | 5 | no |
| GO:0009889 | regulation of biosynthetic process | 29.7297 | 4 | yes |
| GO:0042981 | regulation of apoptotic process | 28.8288 | 6 | yes |
| GO:0043067 | regulation of programmed cell death | 28.8288 | 5 | yes |
| GO:0051173 | positive regulation of nitrogen compound metabolic process | 28.8288 | 5 | yes |
| GO:0009966 | regulation of signal transduction | 28.8288 | 4 | no |
| GO:0010604 | positive regulation of macromolecule metabolic process | 28.8288 | 5 | yes |
| GO:0006996 | organelle organization | 27.9279 | 4 | no |
| GO:0019219 | regulation of nucleobase-containing compound metabolic process | 27.9279 | 5 | yes |
| GO:0006796 | phosphate-containing compound metabolic process | 27.0270 | 4 | yes |
| GO:0010556 | regulation of macromolecule biosynthetic process | 27.0270 | 5 | yes |
| GO:0031325 | positive regulation of cellular metabolic process | 26.1261 | 5 | yes |
| GO:0051252 | regulation of RNA metabolic process | 26.1261 | 5 | yes |
| GO:0009892 | negative regulation of metabolic process | 25.2252 | 4 | no |
| GO:1903506 | regulation of nucleic acid-templated transcription | 24.3243 | 7 | yes |
| GO:2001141 | regulation of RNA biosynthetic process | 24.3243 | 6 | yes |
| GO:0006355 | regulation of DNA-templated transcription | 24.3243 | 6 | yes |
| GO:0010605 | negative regulation of macromolecule metabolic process | 23.4234 | 5 | no |
| GO:0022607 | cellular component assembly | 23.4234 | 4 | no |
| GO:1902531 | regulation of intracellular signal transduction | 22.5225 | 5 | no |
| GO:0051172 | negative regulation of nitrogen compound metabolic process | 22.5225 | 5 | no |
| GO:0051247 | positive regulation of protein metabolic process | 21.6216 | 6 | no |
| GO:0051049 | regulation of transport | 20.7207 | 4 | no |
| GO:0071310 | cellular response to organic substance | 20.7207 | 4 | no |
| GO:0048585 | negative regulation of response to stimulus | 20.7207 | 4 | no |
| GO:0031399 | regulation of protein modification process | 20.7207 | 6 | no |
| GO:0060548 | negative regulation of cell death | 18.9189 | 5 | yes |
| GO:0051094 | positive regulation of developmental process | 18.0180 | 4 | yes |
| GO:1901566 | organonitrogen compound biosynthetic process | 18.0180 | 4 | yes |
| GO:0006753 | nucleoside phosphate metabolic process | 18.0180 | 4 | yes |
| GO:0009117 | nucleotide metabolic process | 18.0180 | 5 | yes |
| GO:0043066 | negative regulation of apoptotic process | 17.1171 | 7 | yes |
| GO:0043069 | negative regulation of programmed cell death | 17.1171 | 6 | yes |
| GO:0044271 | cellular nitrogen compound biosynthetic process | 17.1171 | 4 | yes |
| GO:0045595 | regulation of cell differentiation | 17.1171 | 4 | yes |
| GO:0045935 | positive regulation of nucleobase-containing compound metabolic process | 17.1171 | 6 | yes |
| GO:0009891 | positive regulation of biosynthetic process | 17.1171 | 5 | yes |
| GO:0031328 | positive regulation of cellular biosynthetic process | 16.2162 | 6 | yes |
| GO:0051240 | positive regulation of multicellular organismal process | 16.2162 | 4 | yes |
| GO:0072521 | purine-containing compound metabolic process | 16.2162 | 4 | yes |
| GO:0006163 | purine nucleotide metabolic process | 16.2162 | 5 | yes |
| GO:0006357 | regulation of transcription by RNA polymerase II | 16.2162 | 7 | yes |
| GO:0019693 | ribose phosphate metabolic process | 16.2162 | 4 | yes |
| GO:0009150 | purine ribonucleotide metabolic process | 15.3153 | 6 | yes |
| GO:0009259 | ribonucleotide metabolic process | 15.3153 | 5 | yes |
| GO:0042127 | regulation of cell population proliferation | 13.5135 | 4 | yes |
| GO:0051254 | positive regulation of RNA metabolic process | 13.5135 | 6 | yes |
| GO:0009141 | nucleoside triphosphate metabolic process | 13.5135 | 5 | yes |
| GO:0009144 | purine nucleoside triphosphate metabolic process | 13.5135 | 6 | yes |
| GO:0009199 | ribonucleoside triphosphate metabolic process | 13.5135 | 6 | yes |
| GO:0009205 | purine ribonucleoside triphosphate metabolic process | 13.5135 | 7 | yes |
| GO:0010557 | positive regulation of macromolecule biosynthetic process | 13.5135 | 6 | yes |
| GO:0045893 | positive regulation of DNA-templated transcription | 11.7117 | 7 | yes |
| GO:0090407 | organophosphate biosynthetic process | 11.7117 | 4 | yes |
| GO:1901362 | organic cyclic compound biosynthetic process | 11.7117 | 4 | yes |
| GO:1902680 | positive regulation of RNA biosynthetic process | 11.7117 | 7 | yes |
| GO:1903508 | positive regulation of nucleic acid-templated transcription | 11.7117 | 8 | yes |
| GO:2000026 | regulation of multicellular organismal development | 11.7117 | 4 | yes |
| GO:0016310 | phosphorylation | 11.7117 | 5 | yes |
| GO:0045597 | positive regulation of cell differentiation | 10.8108 | 5 | yes |
| GO:1901137 | carbohydrate derivative biosynthetic process | 10.8108 | 4 | yes |
| GO:0018130 | heterocycle biosynthetic process | 10.8108 | 4 | yes |
| GO:0019438 | aromatic compound biosynthetic process | 9.9099 | 4 | yes |
| GO:0034654 | nucleobase-containing compound biosynthetic process | 9.0090 | 4 | yes |
| GO:0045944 | positive regulation of transcription by RNA polymerase II | 9.0090 | 8 | yes |
| GO:0009132 | nucleoside diphosphate metabolic process | 9.0090 | 5 | yes |
| GO:0046390 | ribose phosphate biosynthetic process | 8.1081 | 5 | yes |
| GO:0072522 | purine-containing compound biosynthetic process | 8.1081 | 5 | yes |
| GO:1901293 | nucleoside phosphate biosynthetic process | 8.1081 | 5 | yes |
| GO:0006164 | purine nucleotide biosynthetic process | 8.1081 | 6 | yes |
| GO:0009165 | nucleotide biosynthetic process | 8.1081 | 6 | yes |
| GO:0046939 | nucleotide phosphorylation | 7.2072 | 6 | yes |
| GO:0006165 | nucleoside diphosphate phosphorylation | 7.2072 | 6 | yes |
| GO:0008284 | positive regulation of cell population proliferation | 7.2072 | 5 | yes |
| GO:0009152 | purine ribonucleotide biosynthetic process | 7.2072 | 7 | yes |
| GO:0009260 | ribonucleotide biosynthetic process | 7.2072 | 6 | yes |
| GO:0009142 | nucleoside triphosphate biosynthetic process | 5.4054 | 6 | yes |
| GO:0046039 | GTP metabolic process | 4.5045 | 7 | yes |
| GO:0046051 | UTP metabolic process | 4.5045 | 7 | yes |
| GO:0050678 | regulation of epithelial cell proliferation | 4.5045 | 5 | yes |
| GO:0072527 | pyrimidine-containing compound metabolic process | 4.5045 | 4 | yes |
| GO:0006220 | pyrimidine nucleotide metabolic process | 4.5045 | 5 | yes |
| GO:0009145 | purine nucleoside triphosphate biosynthetic process | 4.5045 | 7 | yes |
| GO:0009147 | pyrimidine nucleoside triphosphate metabolic process | 4.5045 | 6 | yes |
| GO:0009201 | ribonucleoside triphosphate biosynthetic process | 4.5045 | 7 | yes |
| GO:0009206 | purine ribonucleoside triphosphate biosynthetic process | 4.5045 | 8 | yes |
| GO:0009208 | pyrimidine ribonucleoside triphosphate metabolic process | 4.5045 | 7 | yes |
| GO:0009218 | pyrimidine ribonucleotide metabolic process | 4.5045 | 6 | yes |
| GO:0046036 | CTP metabolic process | 3.6036 | 7 | yes |
| GO:0050679 | positive regulation of epithelial cell proliferation | 3.6036 | 6 | yes |
| GO:0072528 | pyrimidine-containing compound biosynthetic process | 3.6036 | 5 | yes |
| GO:0006183 | GTP biosynthetic process | 3.6036 | 8 | yes |
| GO:0006221 | pyrimidine nucleotide biosynthetic process | 3.6036 | 6 | yes |
| GO:0006228 | UTP biosynthetic process | 3.6036 | 8 | yes |
| GO:0006241 | CTP biosynthetic process | 3.6036 | 8 | yes |
| GO:0009148 | pyrimidine nucleoside triphosphate biosynthetic process | 3.6036 | 7 | yes |
| GO:0009209 | pyrimidine ribonucleoside triphosphate biosynthetic process | 3.6036 | 8 | yes |
| GO:0009220 | pyrimidine ribonucleotide biosynthetic process | 3.6036 | 7 | yes |
| GO:0007229 | integrin-mediated signaling pathway | 2.7027 | 4 | yes |
| GO:0030858 | positive regulation of epithelial cell differentiation | 1.8018 | 6 | yes |
| GO:0045604 | regulation of epidermal cell differentiation | 1.8018 | 5 | yes |
| GO:0045606 | positive regulation of epidermal cell differentiation | 1.8018 | 6 | yes |
| GO:0045616 | regulation of keratinocyte differentiation | 1.8018 | 6 | yes |
| GO:0045618 | positive regulation of keratinocyte differentiation | 1.8018 | 5 | yes |
| GO:0045682 | regulation of epidermis development | 1.8018 | 4 | yes |
| GO:0045684 | positive regulation of epidermis development | 1.8018 | 5 | yes |
| GO:0030856 | regulation of epithelial cell differentiation | 1.8018 | 5 | yes |
Disease
| Term | Name | % | Distance from top the of the tree | Annotated in NDKB_HUMAN |
|---|---|---|---|---|
| DOID:0050700 | cardiomyopathy | 1.8018 | 4 | no |
| DOID:0060036 | intrinsic cardiomyopathy | 1.8018 | 5 | no |
| DOID:114 | heart disease | 1.8018 | 3 | no |
| DOID:12930 | dilated cardiomyopathy | 1.8018 | 6 | no |
All partners
| Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
|---|---|---|---|---|
| PTPRS_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| MYCN_HUMAN | [view interactions] | Low throughput | no | no |
| PHOCN_HUMAN | [view interactions] | Low throughput | no | yes |
| ITBP1_HUMAN | [view interactions] | Low throughput | no | no |
| NDKA_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| NDKB_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| PRKN_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| DYN1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| DYN2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| NDK3_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| HERC3_HUMAN | [view interactions] | Low throughput | no | yes |
| HERC5_HUMAN | [view interactions] | Low throughput | no | yes |
| HERC6_HUMAN | [view interactions] | Low throughput | no | no |
| MDM2_HUMAN | [view interactions] | Low throughput | no | yes |
| TA2R_HUMAN | [view interactions] | Low throughput | no | no |
| RORA_HUMAN | [view interactions] | Low throughput | no | yes |
| VIME_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| GBB1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| WWOX_HUMAN | [view interactions] | High throughput | no | yes |
| SMOC1_HUMAN | [view interactions] | High throughput | no | no |
| NPC2_HUMAN | [view interactions] | High throughput | no | yes |
| FIBB_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| HRG1_HUMAN | [view interactions] | High throughput | no | yes |
| CCNG2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| A4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TAU_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CFAB_HUMAN | [view interactions] | High throughput | no | no |
| OXDA_HUMAN | [view interactions] | High throughput | no | no |
| A2GL_HUMAN | [view interactions] | High throughput | no | no |
| ZN598_HUMAN | [view interactions] | High throughput | no | no |
| HDAC4_HUMAN | [view interactions] | High throughput | no | yes |
| BRAF_HUMAN | [view interactions] | High throughput | no | yes |
| PPP6_HUMAN | [view interactions] | High throughput | no | yes |
| AAR2_HUMAN | [view interactions] | High throughput | no | no |
| PIHD1_HUMAN | [view interactions] | High throughput | no | yes |
| U5S1_HUMAN | [view interactions] | High throughput | no | yes |
| UBC12_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ESR2_HUMAN | [view interactions] | High throughput | no | no |
| PPT1_HUMAN | [view interactions] | High throughput | no | yes |
| WDR76_HUMAN | [view interactions] | High throughput | no | no |
| H4_HUMAN | [view interactions] | High throughput | no | yes |
| H2B1B_HUMAN | [view interactions] | High throughput | no | yes |
| GLUC_HUMAN | [view interactions] | High throughput | no | no |
| ARAF_HUMAN | [view interactions] | High throughput | no | yes |
| BIRC3_HUMAN | [view interactions] | High throughput | no | no |
| LRRK2_HUMAN | [view interactions] | High throughput | no | yes |
| PINK1_HUMAN | [view interactions] | High throughput | no | yes |
| ZCH18_HUMAN | [view interactions] | High throughput | no | yes |
| RCN2_HUMAN | [view interactions] | High throughput | no | yes |
| HSP7C_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HS71B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HS71A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| BAG2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CH60_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| BIP_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| EF1G_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PLBL2_HUMAN | [view interactions] | High throughput | no | yes |
| SYWC_HUMAN | [view interactions] | High throughput | no | yes |
| CALU_HUMAN | [view interactions] | High throughput | no | yes |
| SNUT1_HUMAN | [view interactions] | High throughput | no | yes |
| EFTU_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RT28_HUMAN | [view interactions] | High throughput | no | yes |
| MYLK2_HUMAN | [view interactions] | High throughput | no | no |
| EMC2_HUMAN | [view interactions] | High throughput | no | yes |
| EMC4_HUMAN | [view interactions] | High throughput | no | yes |
| RHG31_HUMAN | [view interactions] | High throughput | no | yes |
| RHG06_HUMAN | [view interactions] | High throughput | no | yes |
| VAV_HUMAN | [view interactions] | High throughput | no | no |
| DOCK8_HUMAN | [view interactions] | High throughput | no | yes |
| RHG18_HUMAN | [view interactions] | High throughput | no | yes |
| RHG44_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ARHG1_HUMAN | [view interactions] | High throughput | no | no |
| OCRL_HUMAN | [view interactions] | High throughput | no | yes |
| SOS1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NINL_HUMAN | [view interactions] | High throughput | no | yes |
| MT21E_HUMAN | [view interactions] | High throughput | no | no |
| UFL1_HUMAN | [view interactions] | High throughput | no | yes |
| DDRGK_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DDAH1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CEL3B_HUMAN | [view interactions] | High throughput | no | no |
| FA24B_HUMAN | [view interactions] | High throughput | no | no |
| ARG39_HUMAN | [view interactions] | High throughput | no | yes |
| WDR47_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TRAIP_HUMAN | [view interactions] | High throughput | no | yes |
| KLK10_HUMAN | [view interactions] | High throughput | no | no |
| FKBP3_HUMAN | [view interactions] | High throughput | no | yes |
| SKP1_HUMAN | [view interactions] | High throughput | no | yes |
| PLCG2_HUMAN | [view interactions] | High throughput | no | yes |
| PILRB_HUMAN | [view interactions] | High throughput | no | yes |
| O10H3_HUMAN | [view interactions] | High throughput | no | no |
| ANF_HUMAN | [view interactions] | High throughput | no | no |
| CSRP3_HUMAN | [view interactions] | High throughput | no | no |
| IER2_HUMAN | [view interactions] | High throughput | no | no |
| GPI8_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| HMGC2_HUMAN | [view interactions] | High throughput | no | no |
| UBB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ZN843_HUMAN | [view interactions] | High throughput | no | yes |
| RMD5A_HUMAN | [view interactions] | High throughput | no | yes |
| SPRTN_HUMAN | [view interactions] | High throughput | no | yes |
| RAC1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ACTN2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ARP2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CAPZB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CP135_HUMAN | [view interactions] | High throughput | no | no |
| SAR1B_HUMAN | [view interactions] | High throughput | no | yes |
| VDAC1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RS3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SODC_HUMAN | [view interactions] | High throughput | no | yes |
| FPPS_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HPRT_HUMAN | [view interactions] | High throughput | no | yes |
| IDHC_HUMAN | [view interactions] | High throughput | no | no |
| TALDO_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| SAHH_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AK1A1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ALDR_HUMAN | [view interactions] | High throughput | no | no |
| AK1BF_HUMAN | [view interactions] | High throughput | no | no |
| ENOA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ENOG_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ENOB_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| FKB1A_HUMAN | [view interactions] | High throughput | no | yes |
| FKB1B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FKBP2_HUMAN | [view interactions] | High throughput | no | yes |
| AATC_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PURA2_HUMAN | [view interactions] | High throughput | no | yes |
| COF1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| COF2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DEST_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HINT1_HUMAN | [view interactions] | High throughput | no | yes |
| LDHA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LDHB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LDHC_HUMAN | [view interactions] | High throughput | no | no |
| OAT_HUMAN | [view interactions] | High throughput | no | yes |
| PIN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SNX3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| TKT_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| WDR1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HIBCH_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PPIF_HUMAN | [view interactions] | High throughput | no | no |
| PRDX5_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SNX12_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TAGL_HUMAN | [view interactions] | High throughput | no | no |
| TAGL2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| TAGL3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| UB2V1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| GBG11_HUMAN | [view interactions] | High throughput | no | no |
| GBG3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RS17_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RL40_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SCO1_HUMAN | [view interactions] | High throughput | no | yes |
| BAG3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| GBG2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KS6A3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KS6A2_HUMAN | [view interactions] | High throughput | no | yes |
| FIS1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MTCH1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| OCAD1_HUMAN | [view interactions] | High throughput | no | yes |
| AKAP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NAA40_HUMAN | [view interactions] | High throughput | no | no |
| NBR1_HUMAN | [view interactions] | High throughput | no | yes |
| RYR1_HUMAN | [view interactions] | High throughput | no | no |
| PER2_HUMAN | [view interactions] | High throughput | no | yes |
| ITB1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| P85A_HUMAN | [view interactions] | High throughput | no | yes |
| IKKB_HUMAN | [view interactions] | High throughput | no | yes |
| MK14_HUMAN | [view interactions] | High throughput | no | yes |
| RHOB_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| GIT2_HUMAN | [view interactions] | High throughput | no | yes |
| NDKM_HUMAN | [view interactions] | High throughput | no | yes |
| BNIPL_HUMAN | [view interactions] | High throughput | no | no |
| GLUT4_HUMAN | [view interactions] | High throughput | no | no |
| 2ABB_HUMAN | [view interactions] | High throughput | no | yes |
| AMOL2_HUMAN | [view interactions] | High throughput | no | no |
| HSF1_HUMAN | [view interactions] | High throughput | no | yes |
| OTUB1_HUMAN | [view interactions] | High throughput | no | yes |
| FMC1_HUMAN | [view interactions] | High throughput | no | no |
| NDUA4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NDUS3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PHIPL_HUMAN | [view interactions] | High throughput | no | yes |
| PPM1K_HUMAN | [view interactions] | High throughput | no | yes |
| OPA3_HUMAN | [view interactions] | High throughput | no | yes |
| PLD3B_HUMAN | [view interactions] | High throughput | no | yes |
| RHG24_HUMAN | [view interactions] | High throughput | no | yes |
| RHG35_HUMAN | [view interactions] | High throughput | no | yes |
| I5P2_HUMAN | [view interactions] | High throughput | no | yes |
| PREX1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| 1433Z_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TBA1A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PPTC7_HUMAN | [view interactions] | High throughput | no | yes |
| PHOP1_HUMAN | [view interactions] | High throughput | no | no |
| PTN23_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RS6_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MP2K2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KLF16_HUMAN | [view interactions] | High throughput | no | yes |
| PP1R7_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KVD28_HUMAN | [view interactions] | High throughput | no | no |
| 5HT1B_HUMAN | [view interactions] | High throughput | no | no |
| PP1R8_HUMAN | [view interactions] | High throughput | no | yes |
| RPAB3_HUMAN | [view interactions] | High throughput | no | yes |
| H2B1C_HUMAN | [view interactions] | High throughput | no | yes |
| CYBP_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PGRC1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RL38_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KAD2_HUMAN | [view interactions] | High throughput | no | no |
| UBE2N_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| INO1_HUMAN | [view interactions] | High throughput | no | no |
| G3BP1_HUMAN | [view interactions] | High throughput | no | yes |
| SET_HUMAN | [view interactions] | High throughput | no | yes |
| PSA2_HUMAN | [view interactions] | High throughput | no | yes |
| STRAP_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| UBE2K_HUMAN | [view interactions] | High throughput | no | yes |
| CBR1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LYSC_HUMAN | [view interactions] | High throughput | no | no |
| RS19_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| PDIA6_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RS16_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PSD12_HUMAN | [view interactions] | High throughput | no | yes |
| LA_HUMAN | [view interactions] | High throughput | no | yes |
| RTN4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| 2AAA_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| PCBP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RPN2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| EPIPL_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ACLY_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RNBP6_HUMAN | [view interactions] | High throughput | no | yes |
| LSM2_HUMAN | [view interactions] | High throughput | no | yes |
| MGN_HUMAN | [view interactions] | High throughput | no | yes |
| RRP44_HUMAN | [view interactions] | High throughput | no | yes |
| STIP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RD23A_HUMAN | [view interactions] | High throughput | no | yes |
| PSA7_HUMAN | [view interactions] | High throughput | no | yes |
| F10A1_HUMAN | [view interactions] | High throughput | no | yes |
| PA1B2_HUMAN | [view interactions] | High throughput | no | yes |
| DYHC1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PSB4_HUMAN | [view interactions] | High throughput | no | yes |
| RUVB2_HUMAN | [view interactions] | High throughput | no | yes |
| EIF3M_HUMAN | [view interactions] | High throughput | no | yes |
| PUR9_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KINH_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| KCNQ1_HUMAN | [view interactions] | High throughput | no | yes |
| CAC1C_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CAV3_HUMAN | [view interactions] | High throughput | no | no |
| CTBP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RAB5A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FXR1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TBB4B_HUMAN | [view interactions] | High throughput | no | yes |
| CDK20_HUMAN | [view interactions] | High throughput | no | yes |
| ESR1_HUMAN | [view interactions] | High throughput | no | no |
| KDM4C_HUMAN | [view interactions] | High throughput | no | no |
| KATIP_HUMAN | [view interactions] | High throughput | no | yes |
| FHI1A_HUMAN | [view interactions] | High throughput | no | yes |
| FHI2A_HUMAN | [view interactions] | High throughput | no | yes |
| SVIL_HUMAN | [view interactions] | High throughput | no | yes |
| TERA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NOS2_HUMAN | [view interactions] | High throughput | no | yes |
| UBC_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TRABD_HUMAN | [view interactions] | High throughput | no | yes |
| MCM2_HUMAN | [view interactions] | High throughput | no | no |
| HYPK_HUMAN | [view interactions] | High throughput | no | no |
| NUD16_HUMAN | [view interactions] | Computational | no | yes |
| CMPK2_HUMAN | [view interactions] | Computational | no | yes |
| KTHY_HUMAN | [view interactions] | Computational | no | yes |
| GCH1_HUMAN | [view interactions] | Computational | no | no |
| KPYM_HUMAN | [view interactions] | Computational | no | yes |
| ITPA_HUMAN | [view interactions] | Computational | no | yes |
| KAD9_HUMAN | [view interactions] | Computational | no | yes |
| KPYR_HUMAN | [view entry] [view interactions] | Computational | yes | no |
| DUT_HUMAN | [view interactions] | Computational | no | yes |
| ENTP2_HUMAN | [view interactions] | Computational | no | yes |
| NTPCR_HUMAN | [view interactions] | Computational | no | yes |
| KGUA_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| PEBP1_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| DCTP1_HUMAN | [view interactions] | Computational | no | no |
| AP4A_HUMAN | [view interactions] | Computational | no | no |
| RL4_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| KAD3_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| NDK7_HUMAN | [view interactions] | Computational | no | yes |
| MESH1_HUMAN | [view interactions] | Computational | no | yes |
| TPIS_HUMAN | [view entry] [view interactions] | Computational | yes | yes |