NDKB_HUMAN
Evidence for PS localization
Functions
Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate . Negatively regulates Rho activity by interacting with AKAP13/LBC (PubMed). Acts as a transcriptional activator of the MYC gene; binds DNA non-specifically (PubMed, PubMed). Binds to both single-stranded guanine- and cytosine-rich strands within the nuclease hypersensitive element (NHE) III(1) region of the MYC gene promoter. Does not bind to duplex NHE III(1) (PubMed). Has G-quadruplex (G4) DNA-binding activity, which is independent of its nucleotide-binding and kinase activity. Binds both folded and unfolded G4 with similar low nanomolar affinities. Stabilizes folded G4s regardless of whether they are prefolded or not (PubMed). Exhibits histidine protein kinase activity (PubMed). [View more on UniProt]
Protein features
Binary interactions with known binding regions
To display all evidence describing the interaction with a partner, click on the protein name left to the bars.
Network
Isoforms
Disease-causing germline mutations
No data found.
Linear motifs
No annotated instance was found. To search for linear motifs, use the ELM prediction server.
Fingerprint
Molecular function
| Term | Name | % | Distance from the top of the tree | Annotated in NDKB_HUMAN |
|---|---|---|---|---|
| GO:0043168 | anion binding | 28.5714 | 4 | yes |
| GO:0003723 | RNA binding | 27.6786 | 4 | no |
| GO:0000166 | nucleotide binding | 27.6786 | 4 | yes |
| GO:0017076 | purine nucleotide binding | 25.8929 | 5 | yes |
| GO:0032555 | purine ribonucleotide binding | 24.1071 | 4 | yes |
| GO:0035639 | purine ribonucleoside triphosphate binding | 23.2143 | 4 | yes |
| GO:0043169 | cation binding | 23.2143 | 4 | yes |
| GO:0046872 | metal ion binding | 22.3214 | 5 | yes |
| GO:0030554 | adenyl nucleotide binding | 19.6429 | 6 | yes |
| GO:0032559 | adenyl ribonucleotide binding | 17.8571 | 5 | yes |
| GO:0005524 | ATP binding | 16.9643 | 5 | yes |
| GO:0032561 | guanyl ribonucleotide binding | 8.9286 | 5 | yes |
| GO:0003677 | DNA binding | 8.9286 | 4 | yes |
| GO:0019001 | guanyl nucleotide binding | 8.9286 | 6 | yes |
| GO:0016301 | kinase activity | 6.2500 | 4 | yes |
| GO:0004674 | protein serine/threonine kinase activity | 4.4643 | 4 | yes |
| GO:0016773 | phosphotransferase activity, alcohol group as acceptor | 4.4643 | 4 | yes |
| GO:0019003 | GDP binding | 4.4643 | 5 | yes |
| GO:0004550 | nucleoside diphosphate kinase activity | 3.5714 | 5 | yes |
| GO:0016776 | phosphotransferase activity, phosphate group as acceptor | 3.5714 | 4 | yes |
| GO:0019205 | nucleobase-containing compound kinase activity | 3.5714 | 5 | yes |
| GO:0033293 | monocarboxylic acid binding | 1.7857 | 5 | yes |
| GO:0051880 | G-quadruplex DNA binding | 1.7857 | 5 | yes |
| GO:0004673 | protein histidine kinase activity | 1.7857 | 4 | yes |
| GO:0016775 | phosphotransferase activity, nitrogenous group as acceptor | 1.7857 | 4 | yes |
| GO:0031406 | carboxylic acid binding | 1.7857 | 4 | yes |
Biological process
| Term | Name | % | Distance from top the of the tree | Annotated in NDKB_HUMAN |
|---|---|---|---|---|
| GO:0048522 | positive regulation of cellular process | 50.8929 | 4 | yes |
| GO:0048523 | negative regulation of cellular process | 46.4286 | 4 | yes |
| GO:0051128 | regulation of cellular component organization | 43.7500 | 4 | yes |
| GO:0031323 | regulation of cellular metabolic process | 41.0714 | 4 | yes |
| GO:0060255 | regulation of macromolecule metabolic process | 41.0714 | 4 | yes |
| GO:0080090 | regulation of primary metabolic process | 40.1786 | 4 | yes |
| GO:0009889 | regulation of biosynthetic process | 35.7143 | 4 | yes |
| GO:0009893 | positive regulation of metabolic process | 35.7143 | 4 | yes |
| GO:0010468 | regulation of gene expression | 33.9286 | 6 | yes |
| GO:0010556 | regulation of macromolecule biosynthetic process | 33.9286 | 5 | yes |
| GO:0031326 | regulation of cellular biosynthetic process | 33.9286 | 5 | yes |
| GO:0010646 | regulation of cell communication | 33.9286 | 4 | no |
| GO:0042981 | regulation of apoptotic process | 30.3571 | 5 | yes |
| GO:0043067 | regulation of programmed cell death | 30.3571 | 4 | yes |
| GO:0006996 | organelle organization | 30.3571 | 4 | no |
| GO:0010604 | positive regulation of macromolecule metabolic process | 29.4643 | 5 | yes |
| GO:0051246 | regulation of protein metabolic process | 29.4643 | 5 | no |
| GO:0006796 | phosphate-containing compound metabolic process | 28.5714 | 4 | yes |
| GO:0009966 | regulation of signal transduction | 28.5714 | 4 | no |
| GO:0019219 | regulation of nucleobase-containing compound metabolic process | 27.6786 | 5 | yes |
| GO:0031325 | positive regulation of cellular metabolic process | 27.6786 | 5 | yes |
| GO:0022607 | cellular component assembly | 27.6786 | 4 | no |
| GO:0009892 | negative regulation of metabolic process | 26.7857 | 4 | no |
| GO:0051252 | regulation of RNA metabolic process | 25.8929 | 5 | yes |
| GO:0080134 | regulation of response to stress | 25.0000 | 4 | no |
| GO:0006355 | regulation of DNA-templated transcription | 24.1071 | 7 | yes |
| GO:0009891 | positive regulation of biosynthetic process | 24.1071 | 5 | yes |
| GO:2001141 | regulation of RNA biosynthetic process | 24.1071 | 6 | yes |
| GO:0010605 | negative regulation of macromolecule metabolic process | 24.1071 | 5 | no |
| GO:0051247 | positive regulation of protein metabolic process | 23.2143 | 6 | no |
| GO:1902531 | regulation of intracellular signal transduction | 22.3214 | 5 | no |
| GO:0010557 | positive regulation of macromolecule biosynthetic process | 21.4286 | 6 | yes |
| GO:0031328 | positive regulation of cellular biosynthetic process | 21.4286 | 6 | yes |
| GO:0051130 | positive regulation of cellular component organization | 21.4286 | 5 | yes |
| GO:0071310 | cellular response to organic substance | 21.4286 | 4 | yes |
| GO:0048584 | positive regulation of response to stimulus | 21.4286 | 4 | no |
| GO:0048585 | negative regulation of response to stimulus | 21.4286 | 4 | no |
| GO:0051049 | regulation of transport | 21.4286 | 4 | no |
| GO:0043933 | protein-containing complex organization | 21.4286 | 4 | no |
| GO:0036211 | protein modification process | 20.5357 | 4 | no |
| GO:0043412 | macromolecule modification | 20.5357 | 4 | no |
| GO:0008104 | protein localization | 20.5357 | 4 | no |
| GO:0031324 | negative regulation of cellular metabolic process | 20.5357 | 5 | no |
| GO:0060341 | regulation of cellular localization | 20.5357 | 4 | no |
| GO:0033043 | regulation of organelle organization | 20.5357 | 5 | no |
| GO:0043066 | negative regulation of apoptotic process | 18.7500 | 6 | yes |
| GO:0043069 | negative regulation of programmed cell death | 18.7500 | 5 | yes |
| GO:0006163 | purine nucleotide metabolic process | 17.8571 | 5 | yes |
| GO:0006753 | nucleoside phosphate metabolic process | 17.8571 | 4 | yes |
| GO:0009117 | nucleotide metabolic process | 17.8571 | 5 | yes |
| GO:0072521 | purine-containing compound metabolic process | 17.8571 | 4 | yes |
| GO:0019693 | ribose phosphate metabolic process | 16.9643 | 4 | yes |
| GO:0031344 | regulation of cell projection organization | 16.9643 | 5 | yes |
| GO:0045935 | positive regulation of nucleobase-containing compound metabolic process | 16.9643 | 5 | yes |
| GO:0051240 | positive regulation of multicellular organismal process | 16.9643 | 4 | yes |
| GO:0120035 | regulation of plasma membrane bounded cell projection organization | 16.9643 | 6 | yes |
| GO:1901566 | organonitrogen compound biosynthetic process | 16.9643 | 4 | yes |
| GO:0006357 | regulation of transcription by RNA polymerase II | 16.0714 | 8 | yes |
| GO:0045595 | regulation of cell differentiation | 16.0714 | 4 | yes |
| GO:0009150 | purine ribonucleotide metabolic process | 15.1786 | 6 | yes |
| GO:0009259 | ribonucleotide metabolic process | 15.1786 | 5 | yes |
| GO:0051094 | positive regulation of developmental process | 15.1786 | 4 | yes |
| GO:0042127 | regulation of cell population proliferation | 14.2857 | 4 | yes |
| GO:0051254 | positive regulation of RNA metabolic process | 13.3929 | 6 | yes |
| GO:1901362 | organic cyclic compound biosynthetic process | 13.3929 | 4 | yes |
| GO:1901701 | cellular response to oxygen-containing compound | 13.3929 | 4 | yes |
| GO:2000026 | regulation of multicellular organismal development | 13.3929 | 4 | yes |
| GO:0010243 | response to organonitrogen compound | 12.5000 | 4 | yes |
| GO:0010975 | regulation of neuron projection development | 12.5000 | 7 | yes |
| GO:0009141 | nucleoside triphosphate metabolic process | 11.6071 | 5 | yes |
| GO:0009144 | purine nucleoside triphosphate metabolic process | 11.6071 | 6 | yes |
| GO:0009199 | ribonucleoside triphosphate metabolic process | 11.6071 | 6 | yes |
| GO:0009205 | purine ribonucleoside triphosphate metabolic process | 11.6071 | 7 | yes |
| GO:0045893 | positive regulation of DNA-templated transcription | 11.6071 | 8 | yes |
| GO:0060284 | regulation of cell development | 11.6071 | 5 | yes |
| GO:1902680 | positive regulation of RNA biosynthetic process | 11.6071 | 7 | yes |
| GO:0033993 | response to lipid | 10.7143 | 4 | yes |
| GO:0034654 | nucleobase-containing compound biosynthetic process | 10.7143 | 4 | yes |
| GO:0051241 | negative regulation of multicellular organismal process | 10.7143 | 4 | yes |
| GO:0090407 | organophosphate biosynthetic process | 10.7143 | 4 | yes |
| GO:1901137 | carbohydrate derivative biosynthetic process | 9.8214 | 4 | yes |
| GO:0034599 | cellular response to oxidative stress | 8.9286 | 4 | yes |
| GO:0045597 | positive regulation of cell differentiation | 8.9286 | 5 | yes |
| GO:0045944 | positive regulation of transcription by RNA polymerase II | 8.9286 | 9 | yes |
| GO:0062197 | cellular response to chemical stress | 8.9286 | 4 | yes |
| GO:0006164 | purine nucleotide biosynthetic process | 8.0357 | 6 | yes |
| GO:0008284 | positive regulation of cell population proliferation | 8.0357 | 5 | yes |
| GO:0009152 | purine ribonucleotide biosynthetic process | 8.0357 | 7 | yes |
| GO:0009165 | nucleotide biosynthetic process | 8.0357 | 6 | yes |
| GO:0009260 | ribonucleotide biosynthetic process | 8.0357 | 6 | yes |
| GO:0031346 | positive regulation of cell projection organization | 8.0357 | 6 | yes |
| GO:0046390 | ribose phosphate biosynthetic process | 8.0357 | 5 | yes |
| GO:0071396 | cellular response to lipid | 8.0357 | 5 | yes |
| GO:0072522 | purine-containing compound biosynthetic process | 8.0357 | 5 | yes |
| GO:1901293 | nucleoside phosphate biosynthetic process | 8.0357 | 5 | yes |
| GO:0051093 | negative regulation of developmental process | 7.1429 | 4 | yes |
| GO:0045596 | negative regulation of cell differentiation | 5.3571 | 5 | yes |
| GO:1903706 | regulation of hemopoiesis | 5.3571 | 4 | yes |
| GO:0002683 | negative regulation of immune system process | 4.4643 | 4 | yes |
| GO:0009142 | nucleoside triphosphate biosynthetic process | 4.4643 | 6 | yes |
| GO:0009145 | purine nucleoside triphosphate biosynthetic process | 4.4643 | 7 | yes |
| GO:0009201 | ribonucleoside triphosphate biosynthetic process | 4.4643 | 7 | yes |
| GO:0009206 | purine ribonucleoside triphosphate biosynthetic process | 4.4643 | 8 | yes |
| GO:0010976 | positive regulation of neuron projection development | 4.4643 | 7 | yes |
| GO:0043434 | response to peptide hormone | 4.4643 | 4 | yes |
| GO:0050678 | regulation of epithelial cell proliferation | 4.4643 | 5 | yes |
| GO:0006183 | GTP biosynthetic process | 3.5714 | 8 | yes |
| GO:0006220 | pyrimidine nucleotide metabolic process | 3.5714 | 5 | yes |
| GO:0006221 | pyrimidine nucleotide biosynthetic process | 3.5714 | 6 | yes |
| GO:0006228 | UTP biosynthetic process | 3.5714 | 8 | yes |
| GO:0006241 | CTP biosynthetic process | 3.5714 | 8 | yes |
| GO:0007188 | adenylate cyclase-modulating G protein-coupled receptor signaling pathway | 3.5714 | 4 | yes |
| GO:0007189 | adenylate cyclase-activating G protein-coupled receptor signaling pathway | 3.5714 | 5 | yes |
| GO:0009147 | pyrimidine nucleoside triphosphate metabolic process | 3.5714 | 6 | yes |
| GO:0009148 | pyrimidine nucleoside triphosphate biosynthetic process | 3.5714 | 7 | yes |
| GO:0009208 | pyrimidine ribonucleoside triphosphate metabolic process | 3.5714 | 7 | yes |
| GO:0009209 | pyrimidine ribonucleoside triphosphate biosynthetic process | 3.5714 | 8 | yes |
| GO:0009218 | pyrimidine ribonucleotide metabolic process | 3.5714 | 6 | yes |
| GO:0009220 | pyrimidine ribonucleotide biosynthetic process | 3.5714 | 7 | yes |
| GO:0010721 | negative regulation of cell development | 3.5714 | 6 | yes |
| GO:0045637 | regulation of myeloid cell differentiation | 3.5714 | 5 | yes |
| GO:0046036 | CTP metabolic process | 3.5714 | 7 | yes |
| GO:0046039 | GTP metabolic process | 3.5714 | 7 | yes |
| GO:0046051 | UTP metabolic process | 3.5714 | 7 | yes |
| GO:0050679 | positive regulation of epithelial cell proliferation | 3.5714 | 6 | yes |
| GO:0072527 | pyrimidine-containing compound metabolic process | 3.5714 | 4 | yes |
| GO:0072528 | pyrimidine-containing compound biosynthetic process | 3.5714 | 5 | yes |
| GO:1902105 | regulation of leukocyte differentiation | 3.5714 | 5 | yes |
| GO:0007229 | integrin-mediated signaling pathway | 2.6786 | 4 | yes |
| GO:0042593 | glucose homeostasis | 2.6786 | 4 | yes |
| GO:0001678 | intracellular glucose homeostasis | 1.7857 | 4 | yes |
| GO:0002761 | regulation of myeloid leukocyte differentiation | 1.7857 | 6 | yes |
| GO:0002762 | negative regulation of myeloid leukocyte differentiation | 1.7857 | 7 | yes |
| GO:0009743 | response to carbohydrate | 1.7857 | 4 | yes |
| GO:0009746 | response to hexose | 1.7857 | 6 | yes |
| GO:0009749 | response to glucose | 1.7857 | 7 | yes |
| GO:0030856 | regulation of epithelial cell differentiation | 1.7857 | 5 | yes |
| GO:0030858 | positive regulation of epithelial cell differentiation | 1.7857 | 6 | yes |
| GO:0034284 | response to monosaccharide | 1.7857 | 5 | yes |
| GO:0045604 | regulation of epidermal cell differentiation | 1.7857 | 5 | yes |
| GO:0045606 | positive regulation of epidermal cell differentiation | 1.7857 | 6 | yes |
| GO:0045616 | regulation of keratinocyte differentiation | 1.7857 | 6 | yes |
| GO:0045618 | positive regulation of keratinocyte differentiation | 1.7857 | 5 | yes |
| GO:0045638 | negative regulation of myeloid cell differentiation | 1.7857 | 6 | yes |
| GO:0045682 | regulation of epidermis development | 1.7857 | 4 | yes |
| GO:0045684 | positive regulation of epidermis development | 1.7857 | 5 | yes |
| GO:0060416 | response to growth hormone | 1.7857 | 5 | yes |
| GO:0070542 | response to fatty acid | 1.7857 | 4 | yes |
| GO:0071322 | cellular response to carbohydrate stimulus | 1.7857 | 5 | yes |
| GO:0071326 | cellular response to monosaccharide stimulus | 1.7857 | 6 | yes |
| GO:0071331 | cellular response to hexose stimulus | 1.7857 | 7 | yes |
| GO:0071333 | cellular response to glucose stimulus | 1.7857 | 5 | yes |
| GO:0071398 | cellular response to fatty acid | 1.7857 | 5 | yes |
| GO:1902106 | negative regulation of leukocyte differentiation | 1.7857 | 6 | yes |
| GO:1903707 | negative regulation of hemopoiesis | 1.7857 | 5 | yes |
Disease
No data found.
All partners
| Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
|---|---|---|---|---|
| NDK3_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| HERC3_HUMAN | [view interactions] | Low throughput | no | yes |
| HERC5_HUMAN | [view interactions] | Low throughput | no | yes |
| HERC6_HUMAN | [view interactions] | Low throughput | no | no |
| MDM2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| TA2R_HUMAN | [view interactions] | Low throughput | no | no |
| RORA_HUMAN | [view interactions] | Low throughput | no | yes |
| VIME_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| GBB1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| PTPRS_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| MYCN_HUMAN | [view interactions] | Low throughput | no | no |
| PHOCN_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| ITBP1_HUMAN | [view interactions] | Low throughput | no | no |
| NDKA_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| NDKB_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| PRKN_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| DYN1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| DYN2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| LSM2_HUMAN | [view interactions] | High throughput | no | yes |
| MGN_HUMAN | [view interactions] | High throughput | no | yes |
| RRP44_HUMAN | [view interactions] | High throughput | no | yes |
| STIP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RD23A_HUMAN | [view interactions] | High throughput | no | yes |
| PSA7_HUMAN | [view interactions] | High throughput | no | yes |
| F10A1_HUMAN | [view interactions] | High throughput | no | yes |
| PA1B2_HUMAN | [view interactions] | High throughput | no | yes |
| DYHC1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PSB4_HUMAN | [view interactions] | High throughput | no | yes |
| RUVB2_HUMAN | [view interactions] | High throughput | no | yes |
| EIF3M_HUMAN | [view interactions] | High throughput | no | yes |
| PUR9_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KINH_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| KCNQ1_HUMAN | [view interactions] | High throughput | no | yes |
| CAC1C_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CAV3_HUMAN | [view interactions] | High throughput | no | no |
| CTBP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RAB5A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FXR1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TBB4B_HUMAN | [view interactions] | High throughput | no | yes |
| CDK20_HUMAN | [view interactions] | High throughput | no | yes |
| ESR1_HUMAN | [view interactions] | High throughput | no | no |
| KDM4C_HUMAN | [view interactions] | High throughput | no | no |
| KATIP_HUMAN | [view interactions] | High throughput | no | yes |
| FHI1A_HUMAN | [view interactions] | High throughput | no | yes |
| FHI2A_HUMAN | [view interactions] | High throughput | no | yes |
| CFTR_HUMAN | [view interactions] | High throughput | no | no |
| SVIL_HUMAN | [view interactions] | High throughput | no | yes |
| TERA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NOS2_HUMAN | [view interactions] | High throughput | no | yes |
| UBC_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TRABD_HUMAN | [view interactions] | High throughput | no | yes |
| MCM2_HUMAN | [view interactions] | High throughput | no | no |
| HYPK_HUMAN | [view interactions] | High throughput | no | no |
| WWOX_HUMAN | [view interactions] | High throughput | no | yes |
| SMOC1_HUMAN | [view interactions] | High throughput | no | no |
| NPC2_HUMAN | [view interactions] | High throughput | no | yes |
| FIBB_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| HRG1_HUMAN | [view interactions] | High throughput | no | yes |
| CCNG2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| A4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TAU_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CFAB_HUMAN | [view interactions] | High throughput | no | no |
| OXDA_HUMAN | [view interactions] | High throughput | no | no |
| A2GL_HUMAN | [view interactions] | High throughput | no | no |
| ZN598_HUMAN | [view interactions] | High throughput | no | no |
| HDAC4_HUMAN | [view interactions] | High throughput | no | yes |
| BRAF_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PPP6_HUMAN | [view interactions] | High throughput | no | yes |
| AAR2_HUMAN | [view interactions] | High throughput | no | no |
| PIHD1_HUMAN | [view interactions] | High throughput | no | yes |
| U5S1_HUMAN | [view interactions] | High throughput | no | yes |
| UBC12_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ESR2_HUMAN | [view interactions] | High throughput | no | no |
| PPT1_HUMAN | [view interactions] | High throughput | no | yes |
| WDR76_HUMAN | [view interactions] | High throughput | no | no |
| H4_HUMAN | [view interactions] | High throughput | no | yes |
| H2B1B_HUMAN | [view interactions] | High throughput | no | yes |
| GLUC_HUMAN | [view interactions] | High throughput | no | no |
| ARAF_HUMAN | [view interactions] | High throughput | no | yes |
| BIRC3_HUMAN | [view interactions] | High throughput | no | no |
| LRRK2_HUMAN | [view interactions] | High throughput | no | yes |
| PINK1_HUMAN | [view interactions] | High throughput | no | yes |
| ZCH18_HUMAN | [view interactions] | High throughput | no | yes |
| RCN2_HUMAN | [view interactions] | High throughput | no | yes |
| HSP7C_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HS71B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HS71A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| BAG2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CH60_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| BIP_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| EF1G_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PLBL2_HUMAN | [view interactions] | High throughput | no | yes |
| SYWC_HUMAN | [view interactions] | High throughput | no | yes |
| CALU_HUMAN | [view interactions] | High throughput | no | yes |
| SNUT1_HUMAN | [view interactions] | High throughput | no | yes |
| EFTU_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RT28_HUMAN | [view interactions] | High throughput | no | yes |
| MYLK2_HUMAN | [view interactions] | High throughput | no | no |
| EMC2_HUMAN | [view interactions] | High throughput | no | yes |
| EMC4_HUMAN | [view interactions] | High throughput | no | yes |
| RHG31_HUMAN | [view interactions] | High throughput | no | yes |
| RHG06_HUMAN | [view interactions] | High throughput | no | yes |
| VAV_HUMAN | [view interactions] | High throughput | no | no |
| DOCK8_HUMAN | [view interactions] | High throughput | no | yes |
| RHG18_HUMAN | [view interactions] | High throughput | no | yes |
| RHG44_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ARHG1_HUMAN | [view interactions] | High throughput | no | no |
| OCRL_HUMAN | [view interactions] | High throughput | no | yes |
| SOS1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NINL_HUMAN | [view interactions] | High throughput | no | yes |
| MT21E_HUMAN | [view interactions] | High throughput | no | no |
| UFL1_HUMAN | [view interactions] | High throughput | no | yes |
| DDRGK_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DDAH1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CEL3B_HUMAN | [view interactions] | High throughput | no | no |
| FA24B_HUMAN | [view interactions] | High throughput | no | no |
| ARG39_HUMAN | [view interactions] | High throughput | no | yes |
| WDR47_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TRAIP_HUMAN | [view interactions] | High throughput | no | yes |
| KLK10_HUMAN | [view interactions] | High throughput | no | no |
| FKBP3_HUMAN | [view interactions] | High throughput | no | yes |
| SKP1_HUMAN | [view interactions] | High throughput | no | yes |
| PLCG2_HUMAN | [view interactions] | High throughput | no | yes |
| PILRB_HUMAN | [view interactions] | High throughput | no | yes |
| O10H3_HUMAN | [view interactions] | High throughput | no | no |
| ANF_HUMAN | [view interactions] | High throughput | no | no |
| CSRP3_HUMAN | [view interactions] | High throughput | no | no |
| IER2_HUMAN | [view interactions] | High throughput | no | no |
| GPI8_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| HMGC2_HUMAN | [view interactions] | High throughput | no | no |
| UBB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ZN843_HUMAN | [view interactions] | High throughput | no | yes |
| RMD5A_HUMAN | [view interactions] | High throughput | no | yes |
| SPRTN_HUMAN | [view interactions] | High throughput | no | yes |
| RAC1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ACTN2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ARP2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CAPZB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CP135_HUMAN | [view interactions] | High throughput | no | no |
| SAR1B_HUMAN | [view interactions] | High throughput | no | yes |
| VDAC1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HDAC6_HUMAN | [view interactions] | High throughput | no | yes |
| OVOL2_HUMAN | [view interactions] | High throughput | no | no |
| ZRAN1_HUMAN | [view interactions] | High throughput | no | yes |
| BAP1_HUMAN | [view interactions] | High throughput | no | yes |
| RUFY1_HUMAN | [view interactions] | High throughput | no | yes |
| TRI67_HUMAN | [view interactions] | High throughput | no | no |
| ASXL1_HUMAN | [view interactions] | High throughput | no | no |
| ASXL2_HUMAN | [view interactions] | High throughput | no | no |
| ASXL3_HUMAN | [view interactions] | High throughput | no | no |
| EZH2_HUMAN | [view interactions] | High throughput | no | no |
| CL16A_HUMAN | [view interactions] | High throughput | no | yes |
| GOLI_HUMAN | [view interactions] | High throughput | no | yes |
| RN149_HUMAN | [view interactions] | High throughput | no | no |
| SMC5_HUMAN | [view interactions] | High throughput | no | yes |
| UBE2H_HUMAN | [view interactions] | High throughput | no | yes |
| RS3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SODC_HUMAN | [view interactions] | High throughput | no | yes |
| FPPS_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HPRT_HUMAN | [view interactions] | High throughput | no | yes |
| IDHC_HUMAN | [view interactions] | High throughput | no | no |
| TALDO_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| SAHH_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AK1A1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ALDR_HUMAN | [view interactions] | High throughput | no | no |
| AK1BF_HUMAN | [view interactions] | High throughput | no | no |
| ENOA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ENOG_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ENOB_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| FKB1A_HUMAN | [view interactions] | High throughput | no | yes |
| FKB1B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FKBP2_HUMAN | [view interactions] | High throughput | no | yes |
| AATC_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PURA2_HUMAN | [view interactions] | High throughput | no | yes |
| COF1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| COF2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DEST_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HINT1_HUMAN | [view interactions] | High throughput | no | yes |
| LDHA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LDHB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LDHC_HUMAN | [view interactions] | High throughput | no | no |
| OAT_HUMAN | [view interactions] | High throughput | no | yes |
| PIN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SNX3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| TKT_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| WDR1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HIBCH_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PPIF_HUMAN | [view interactions] | High throughput | no | no |
| PRDX5_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SNX12_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TAGL_HUMAN | [view interactions] | High throughput | no | no |
| TAGL2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| TAGL3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RYR1_HUMAN | [view interactions] | High throughput | no | no |
| UB2V1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ITB1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| GBG11_HUMAN | [view interactions] | High throughput | no | no |
| P85A_HUMAN | [view interactions] | High throughput | no | yes |
| GBG3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| IKKB_HUMAN | [view interactions] | High throughput | no | yes |
| RS17_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MK14_HUMAN | [view interactions] | High throughput | no | yes |
| RL40_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SCO1_HUMAN | [view interactions] | High throughput | no | yes |
| RHOB_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| BAG3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| GBG2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GIT2_HUMAN | [view interactions] | High throughput | no | yes |
| BACH_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NDKM_HUMAN | [view interactions] | High throughput | no | yes |
| PIR_HUMAN | [view interactions] | High throughput | no | no |
| BNIPL_HUMAN | [view interactions] | High throughput | no | no |
| DLDH_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KPYM_HUMAN | [view interactions] | High throughput | no | yes |
| GLUT4_HUMAN | [view interactions] | High throughput | no | no |
| S10AB_HUMAN | [view interactions] | High throughput | no | no |
| 2ABB_HUMAN | [view interactions] | High throughput | no | yes |
| AK1C3_HUMAN | [view interactions] | High throughput | no | yes |
| AMOL2_HUMAN | [view interactions] | High throughput | no | no |
| HNRPD_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HSF1_HUMAN | [view interactions] | High throughput | no | yes |
| KS6A3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| OTUB1_HUMAN | [view interactions] | High throughput | no | yes |
| KS6A2_HUMAN | [view interactions] | High throughput | no | yes |
| FMC1_HUMAN | [view interactions] | High throughput | no | no |
| FIS1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NDUA4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MTCH1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NDUS3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| OCAD1_HUMAN | [view interactions] | High throughput | no | yes |
| PHIPL_HUMAN | [view interactions] | High throughput | no | yes |
| AKAP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| OPA3_HUMAN | [view interactions] | High throughput | no | yes |
| NAA40_HUMAN | [view interactions] | High throughput | no | no |
| PPM1K_HUMAN | [view interactions] | High throughput | no | yes |
| NBR1_HUMAN | [view interactions] | High throughput | no | yes |
| PLD3B_HUMAN | [view interactions] | High throughput | no | yes |
| PER2_HUMAN | [view interactions] | High throughput | no | yes |
| STING_HUMAN | [view interactions] | High throughput | no | yes |
| RHG24_HUMAN | [view interactions] | High throughput | no | yes |
| CAVN3_HUMAN | [view interactions] | High throughput | no | no |
| RHG35_HUMAN | [view interactions] | High throughput | no | yes |
| H33_HUMAN | [view interactions] | High throughput | no | yes |
| I5P2_HUMAN | [view interactions] | High throughput | no | yes |
| KDM1A_HUMAN | [view interactions] | High throughput | no | yes |
| PREX1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| TGON2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RFA1_HUMAN | [view interactions] | High throughput | no | yes |
| 1433Z_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RFA2_HUMAN | [view interactions] | High throughput | no | yes |
| TBA1A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RFA3_HUMAN | [view interactions] | High throughput | no | yes |
| PPTC7_HUMAN | [view interactions] | High throughput | no | yes |
| PHOP1_HUMAN | [view interactions] | High throughput | no | no |
| PTN23_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RS6_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MP2K2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KLF16_HUMAN | [view interactions] | High throughput | no | yes |
| PP1R7_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KVD28_HUMAN | [view interactions] | High throughput | no | no |
| 5HT1B_HUMAN | [view interactions] | High throughput | no | no |
| PP1R8_HUMAN | [view interactions] | High throughput | no | yes |
| RPAB3_HUMAN | [view interactions] | High throughput | no | yes |
| H2B1C_HUMAN | [view interactions] | High throughput | no | yes |
| CYBP_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PGRC1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RL38_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KAD2_HUMAN | [view interactions] | High throughput | no | no |
| UBE2N_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| INO1_HUMAN | [view interactions] | High throughput | no | no |
| G3BP1_HUMAN | [view interactions] | High throughput | no | yes |
| SET_HUMAN | [view interactions] | High throughput | no | yes |
| PSA2_HUMAN | [view interactions] | High throughput | no | yes |
| STRAP_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| UBE2K_HUMAN | [view interactions] | High throughput | no | yes |
| CBR1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LYSC_HUMAN | [view interactions] | High throughput | no | no |
| RS19_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| PDIA6_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RS16_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PSD12_HUMAN | [view interactions] | High throughput | no | yes |
| LA_HUMAN | [view interactions] | High throughput | no | yes |
| RTN4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| 2AAA_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| PCBP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RPN2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| EPIPL_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ACLY_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RNBP6_HUMAN | [view interactions] | High throughput | no | yes |