WDR1_HUMAN
Induces disassembly of actin filaments in conjunction with ADF/cofilin family proteins (PubMed, PubMed, PubMed). Enhances cofilin-mediated actin severing . Involved in cytokinesis. Involved in chemotactic cell migration by restricting lamellipodial membrane protrusions (PubMed). Involved in myocardium sarcomere organization. Required for cardiomyocyte growth and maintenance . Involved in megakaryocyte maturation and platelet shedding. Required for the establishment of planar cell polarity (PCP) during follicular epithelium development and for cell shape changes during PCP; the function seems to implicate cooperation with CFL1 and/or DSTN/ADF. Involved in the generation/maintenance of cortical tension . Involved in assembly and maintenance of epithelial apical cell junctions and plays a role in the organization of the perijunctional actomyosin belt (PubMed). [View more on UniProt]
Interacting region for partners were not defined.
| Position | Amino acid | Mutation | Disease | Overlap with binding region |
|---|---|---|---|---|
| 293 | Leu | Phe | Periodicfever,immunodeficiency,andthrombocytopeniasyndrome(PFITS) | - |
| 572 | Asp | Val | Periodicfever,immunodeficiency,andthrombocytopeniasyndrome(PFITS) | - |
No annotated instance was found. To search for linear motifs, use the ELM prediction server.
Molecular function
| Term | Name | % | Distance from the top of the tree | Annotated in WDR1_HUMAN |
|---|---|---|---|---|
| GO:0043168 | anion binding | 36.2500 | 4 | no |
| GO:0000166 | nucleotide binding | 35.0000 | 4 | no |
| GO:0017076 | purine nucleotide binding | 35.0000 | 5 | no |
| GO:0032555 | purine ribonucleotide binding | 32.5000 | 4 | no |
| GO:0035639 | purine ribonucleoside triphosphate binding | 31.2500 | 4 | no |
| GO:0003779 | actin binding | 27.5000 | 4 | yes |
| GO:0030554 | adenyl nucleotide binding | 26.2500 | 6 | no |
| GO:0003723 | RNA binding | 26.2500 | 4 | no |
| GO:0045296 | cadherin binding | 25.0000 | 4 | no |
| GO:0032559 | adenyl ribonucleotide binding | 23.7500 | 5 | no |
| GO:0019900 | kinase binding | 23.7500 | 4 | no |
| GO:0005524 | ATP binding | 22.5000 | 5 | no |
| GO:0043169 | cation binding | 21.2500 | 4 | no |
| GO:0046872 | metal ion binding | 21.2500 | 5 | no |
Biological process
| Term | Name | % | Distance from top the of the tree | Annotated in WDR1_HUMAN |
|---|---|---|---|---|
| GO:0048522 | positive regulation of cellular process | 62.5000 | 4 | yes |
| GO:0051128 | regulation of cellular component organization | 55.0000 | 4 | yes |
| GO:0031323 | regulation of cellular metabolic process | 55.0000 | 4 | no |
| GO:0048523 | negative regulation of cellular process | 52.5000 | 4 | no |
| GO:0060255 | regulation of macromolecule metabolic process | 50.0000 | 4 | no |
| GO:0009889 | regulation of biosynthetic process | 46.2500 | 4 | no |
| GO:0010468 | regulation of gene expression | 45.0000 | 6 | no |
| GO:0010556 | regulation of macromolecule biosynthetic process | 45.0000 | 5 | no |
| GO:0031326 | regulation of cellular biosynthetic process | 45.0000 | 5 | no |
| GO:0009893 | positive regulation of metabolic process | 41.2500 | 4 | no |
| GO:0080090 | regulation of primary metabolic process | 41.2500 | 4 | no |
| GO:0008104 | protein localization | 40.0000 | 4 | no |
| GO:0010604 | positive regulation of macromolecule metabolic process | 38.7500 | 5 | no |
| GO:0031325 | positive regulation of cellular metabolic process | 38.7500 | 5 | no |
| GO:0006996 | organelle organization | 37.5000 | 4 | yes |
| GO:0033043 | regulation of organelle organization | 36.2500 | 5 | yes |
| GO:0010646 | regulation of cell communication | 35.0000 | 4 | no |
| GO:0022607 | cellular component assembly | 33.7500 | 4 | yes |
| GO:0009966 | regulation of signal transduction | 33.7500 | 4 | no |
| GO:0051130 | positive regulation of cellular component organization | 32.5000 | 5 | yes |
| GO:0009891 | positive regulation of biosynthetic process | 32.5000 | 5 | no |
| GO:0010557 | positive regulation of macromolecule biosynthetic process | 31.2500 | 6 | no |
| GO:0031328 | positive regulation of cellular biosynthetic process | 31.2500 | 6 | no |
| GO:0044087 | regulation of cellular component biogenesis | 31.2500 | 4 | no |
| GO:0051246 | regulation of protein metabolic process | 31.2500 | 5 | no |
| GO:0051240 | positive regulation of multicellular organismal process | 30.0000 | 4 | no |
| GO:0007010 | cytoskeleton organization | 28.7500 | 5 | yes |
| GO:0006796 | phosphate-containing compound metabolic process | 28.7500 | 4 | no |
| GO:0043933 | protein-containing complex organization | 27.5000 | 4 | yes |
| GO:0009892 | negative regulation of metabolic process | 27.5000 | 4 | no |
| GO:0010628 | positive regulation of gene expression | 26.2500 | 7 | no |
| GO:0042981 | regulation of apoptotic process | 26.2500 | 5 | no |
| GO:0043067 | regulation of programmed cell death | 26.2500 | 4 | no |
| GO:0031324 | negative regulation of cellular metabolic process | 26.2500 | 5 | no |
| GO:0071310 | cellular response to organic substance | 26.2500 | 4 | no |
| GO:0019219 | regulation of nucleobase-containing compound metabolic process | 26.2500 | 5 | no |
| GO:0051493 | regulation of cytoskeleton organization | 25.0000 | 6 | yes |
| GO:0051049 | regulation of transport | 25.0000 | 4 | no |
| GO:0010605 | negative regulation of macromolecule metabolic process | 25.0000 | 5 | no |
| GO:0048584 | positive regulation of response to stimulus | 25.0000 | 4 | no |
| GO:0060341 | regulation of cellular localization | 25.0000 | 4 | no |
| GO:0051252 | regulation of RNA metabolic process | 25.0000 | 5 | no |
| GO:0097435 | supramolecular fiber organization | 23.7500 | 4 | yes |
| GO:1902903 | regulation of supramolecular fiber organization | 23.7500 | 5 | yes |
| GO:0009894 | regulation of catabolic process | 23.7500 | 4 | no |
| GO:0032880 | regulation of protein localization | 23.7500 | 5 | no |
| GO:0042127 | regulation of cell population proliferation | 23.7500 | 4 | no |
| GO:1902531 | regulation of intracellular signal transduction | 23.7500 | 5 | no |
| GO:0009890 | negative regulation of biosynthetic process | 22.5000 | 5 | no |
| GO:0010558 | negative regulation of macromolecule biosynthetic process | 22.5000 | 6 | no |
| GO:0031327 | negative regulation of cellular biosynthetic process | 22.5000 | 6 | no |
| GO:0006355 | regulation of DNA-templated transcription | 22.5000 | 7 | no |
| GO:0051094 | positive regulation of developmental process | 22.5000 | 4 | no |
| GO:2001141 | regulation of RNA biosynthetic process | 22.5000 | 6 | no |
| GO:0071702 | organic substance transport | 22.5000 | 4 | no |
| GO:0071705 | nitrogen compound transport | 22.5000 | 4 | no |
| GO:0051247 | positive regulation of protein metabolic process | 22.5000 | 6 | no |
| GO:0010638 | positive regulation of organelle organization | 21.2500 | 6 | yes |
| GO:0022603 | regulation of anatomical structure morphogenesis | 21.2500 | 4 | yes |
| GO:0014070 | response to organic cyclic compound | 21.2500 | 4 | no |
| GO:0009967 | positive regulation of signal transduction | 21.2500 | 5 | no |
| GO:0010647 | positive regulation of cell communication | 21.2500 | 5 | no |
| GO:0023056 | positive regulation of signaling | 21.2500 | 4 | no |
| GO:0007015 | actin filament organization | 20.0000 | 5 | yes |
| GO:0032970 | regulation of actin filament-based process | 18.7500 | 4 | yes |
| GO:0032956 | regulation of actin cytoskeleton organization | 17.5000 | 5 | yes |
| GO:0045595 | regulation of cell differentiation | 17.5000 | 4 | yes |
| GO:0110053 | regulation of actin filament organization | 17.5000 | 6 | yes |
| GO:0051495 | positive regulation of cytoskeleton organization | 15.0000 | 7 | yes |
| GO:1902905 | positive regulation of supramolecular fiber organization | 15.0000 | 6 | yes |
| GO:0022604 | regulation of cell morphogenesis | 13.7500 | 5 | yes |
| GO:0032535 | regulation of cellular component size | 13.7500 | 4 | yes |
| GO:0008064 | regulation of actin polymerization or depolymerization | 11.2500 | 6 | yes |
| GO:0022411 | cellular component disassembly | 11.2500 | 4 | yes |
| GO:0030832 | regulation of actin filament length | 11.2500 | 5 | yes |
| GO:0034330 | cell junction organization | 11.2500 | 4 | yes |
| GO:0032984 | protein-containing complex disassembly | 10.0000 | 5 | yes |
| GO:0030834 | regulation of actin filament depolymerization | 8.7500 | 7 | yes |
| GO:0031032 | actomyosin structure organization | 8.7500 | 4 | yes |
| GO:0034329 | cell junction assembly | 8.7500 | 5 | yes |
| GO:0043244 | regulation of protein-containing complex disassembly | 8.7500 | 5 | yes |
| GO:1901879 | regulation of protein depolymerization | 8.7500 | 6 | yes |
| GO:0008154 | actin polymerization or depolymerization | 7.5000 | 6 | yes |
| GO:0045216 | cell-cell junction organization | 7.5000 | 5 | yes |
| GO:0051261 | protein depolymerization | 7.5000 | 6 | yes |
| GO:0007043 | cell-cell junction assembly | 6.2500 | 6 | yes |
| GO:0030042 | actin filament depolymerization | 6.2500 | 7 | yes |
| GO:0030043 | actin filament fragmentation | 5.0000 | 8 | yes |
| GO:0030099 | myeloid cell differentiation | 5.0000 | 4 | yes |
| GO:0045214 | sarcomere organization | 5.0000 | 5 | yes |
| GO:0030836 | positive regulation of actin filament depolymerization | 3.7500 | 7 | yes |
| GO:0030865 | cortical cytoskeleton organization | 3.7500 | 6 | yes |
| GO:0035088 | establishment or maintenance of apical/basal cell polarity | 3.7500 | 4 | yes |
| GO:0043243 | positive regulation of protein-containing complex disassembly | 3.7500 | 6 | yes |
| GO:0099623 | regulation of cardiac muscle cell membrane repolarization | 3.7500 | 4 | yes |
| GO:1901881 | positive regulation of protein depolymerization | 3.7500 | 7 | yes |
| GO:0045197 | establishment or maintenance of epithelial cell apical/basal polarity | 2.5000 | 5 | yes |
| GO:0045685 | regulation of glial cell differentiation | 2.5000 | 5 | yes |
| GO:0048713 | regulation of oligodendrocyte differentiation | 2.5000 | 6 | yes |
| GO:0060307 | regulation of ventricular cardiac muscle cell membrane repolarization | 2.5000 | 5 | yes |
| GO:0097530 | granulocyte migration | 2.5000 | 4 | yes |
| GO:1990266 | neutrophil migration | 2.5000 | 5 | yes |
Disease
No data found.
| Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
|---|---|---|---|---|
| UBP7_HUMAN | [view interactions] | Low throughput | no | yes |
| SYVN1_HUMAN | [view interactions] | Low throughput | no | yes |
| KEAP1_HUMAN | [view interactions] | Low throughput | no | yes |
| M3K7_HUMAN | [view interactions] | Low throughput | no | yes |
| CTNB1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| SKI2_HUMAN | [view interactions] | High throughput | no | yes |
| GRB2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CSK2B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HSPB2_HUMAN | [view interactions] | High throughput | no | yes |
| ILK_HUMAN | [view interactions] | High throughput | no | no |
| BIRC3_HUMAN | [view interactions] | High throughput | no | no |
| BIRC2_HUMAN | [view interactions] | High throughput | no | yes |
| MYH9_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ANLN_HUMAN | [view interactions] | High throughput | no | yes |
| MY18A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MYO1C_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MYO19_HUMAN | [view interactions] | High throughput | no | yes |
| FLNA_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| LIMA1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CALL3_HUMAN | [view interactions] | High throughput | no | yes |
| TMOD3_HUMAN | [view interactions] | High throughput | no | yes |
| TPM1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| COR1C_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DREB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SYNPO_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| MARE1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CAZA2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| IQGA1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| PP1B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NU107_HUMAN | [view interactions] | High throughput | no | no |
| POTEE_HUMAN | [view interactions] | High throughput | no | no |
| SH3L1_HUMAN | [view interactions] | High throughput | no | yes |
| ZBT18_HUMAN | [view interactions] | High throughput | no | yes |
| P53_HUMAN | [view interactions] | High throughput | no | no |
| PK3CA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ACTB_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CFTR_HUMAN | [view interactions] | High throughput | no | no |
| CALX_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AKT3_HUMAN | [view interactions] | High throughput | no | yes |
| MB212_HUMAN | [view interactions] | High throughput | no | no |
| VMP1_HUMAN | [view interactions] | High throughput | no | yes |
| STAT3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ACADS_HUMAN | [view interactions] | High throughput | no | yes |
| DAPK1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PIM3_HUMAN | [view interactions] | High throughput | no | no |
| TBCK_HUMAN | [view interactions] | High throughput | no | yes |
| HASP_HUMAN | [view interactions] | High throughput | no | yes |
| TR10D_HUMAN | [view interactions] | High throughput | no | no |
| PKHA7_HUMAN | [view interactions] | High throughput | no | yes |
| MYCB2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CAV3_HUMAN | [view interactions] | High throughput | no | no |
| TX101_HUMAN | [view interactions] | High throughput | no | no |
| BMI1_HUMAN | [view interactions] | High throughput | no | yes |
| HCN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CEP63_HUMAN | [view interactions] | High throughput | no | yes |
| SRPK1_HUMAN | [view interactions] | High throughput | no | yes |
| RB33B_HUMAN | [view interactions] | High throughput | no | no |
| RAB5C_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RAB21_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RAB19_HUMAN | [view interactions] | High throughput | no | no |
| RAB4A_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RAB1A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RAB35_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RAB4B_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RB27B_HUMAN | [view interactions] | High throughput | no | no |
| NECD_HUMAN | [view interactions] | High throughput | no | no |
| FOS_HUMAN | [view interactions] | High throughput | no | yes |
| STAT1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| SKI8_HUMAN | [view interactions] | High throughput | no | yes |
| CDC73_HUMAN | [view interactions] | High throughput | no | yes |
| LEO1_HUMAN | [view interactions] | High throughput | no | yes |
| SF3B4_HUMAN | [view interactions] | High throughput | no | yes |
| RUVB2_HUMAN | [view interactions] | High throughput | no | yes |
| RUVB1_HUMAN | [view interactions] | High throughput | no | yes |
| SUMO3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ISG15_HUMAN | [view interactions] | High throughput | no | no |
| CDK2_HUMAN | [view interactions] | High throughput | no | yes |
| UBC_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| BAG3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CUL3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MOV10_HUMAN | [view interactions] | High throughput | no | no |
| NXF1_HUMAN | [view interactions] | High throughput | no | yes |
| EED_HUMAN | [view interactions] | High throughput | no | yes |
| ABCE1_HUMAN | [view interactions] | High throughput | no | yes |
| AMRA1_HUMAN | [view interactions] | High throughput | no | yes |
| NTRK1_HUMAN | [view interactions] | High throughput | no | yes |
| PPME1_HUMAN | [view interactions] | High throughput | no | yes |
| U2AF2_HUMAN | [view interactions] | High throughput | no | yes |
| ATRX_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TRI25_HUMAN | [view interactions] | High throughput | no | yes |
| YAP1_HUMAN | [view interactions] | High throughput | no | yes |
| CXA1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PURA2_HUMAN | [view interactions] | High throughput | no | yes |
| RNF4_HUMAN | [view interactions] | High throughput | no | yes |
| NEB2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MYC_HUMAN | [view interactions] | High throughput | no | yes |
| ACTC_HUMAN | [view interactions] | High throughput | no | no |
| UBP14_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| APEX1_HUMAN | [view interactions] | High throughput | no | yes |
| TAU_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DUS28_HUMAN | [view interactions] | High throughput | no | yes |
| TIF1B_HUMAN | [view interactions] | High throughput | no | yes |
| CUL7_HUMAN | [view interactions] | High throughput | no | yes |
| PKHA4_HUMAN | [view interactions] | High throughput | no | yes |
| MAGA3_HUMAN | [view interactions] | High throughput | no | no |
| VAV_HUMAN | [view interactions] | High throughput | no | no |
| CTRO_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CHM4B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CHM4C_HUMAN | [view interactions] | High throughput | no | yes |
| ECT2_HUMAN | [view interactions] | High throughput | no | no |
| KIF14_HUMAN | [view interactions] | High throughput | no | no |
| KI20A_HUMAN | [view interactions] | High throughput | no | yes |
| PRC1_HUMAN | [view interactions] | High throughput | no | yes |
| NUPR1_HUMAN | [view interactions] | High throughput | no | no |
| BRD4_HUMAN | [view interactions] | High throughput | no | yes |
| RBM39_HUMAN | [view interactions] | High throughput | no | yes |
| RIGI_HUMAN | [view interactions] | High throughput | no | yes |
| TOP3B_HUMAN | [view interactions] | High throughput | no | no |
| TFR1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CATL1_HUMAN | [view interactions] | High throughput | no | yes |
| CATB_HUMAN | [view interactions] | High throughput | no | yes |
| IFM1_HUMAN | [view interactions] | High throughput | no | no |
| CATS_HUMAN | [view interactions] | High throughput | no | no |
| DPP4_HUMAN | [view interactions] | High throughput | no | no |
| BASI_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| IFM3_HUMAN | [view interactions] | High throughput | no | yes |
| CLC4D_HUMAN | [view interactions] | High throughput | no | no |
| TMPS4_HUMAN | [view interactions] | High throughput | no | yes |
| CLC4E_HUMAN | [view interactions] | High throughput | no | no |
| DDB1_HUMAN | [view interactions] | High throughput | no | yes |
| RHOD_HUMAN | [view interactions] | High throughput | no | no |
| RHOV_HUMAN | [view interactions] | High throughput | no | no |
| RHBT2_HUMAN | [view interactions] | High throughput | no | no |
| PLK4_HUMAN | [view interactions] | High throughput | no | yes |
| SOX2_HUMAN | [view interactions] | High throughput | no | yes |
| ACTG_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CAPZB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SRC8_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SAR1B_HUMAN | [view interactions] | High throughput | no | yes |
| ANM1_HUMAN | [view interactions] | High throughput | no | yes |
| FOXC1_HUMAN | [view interactions] | High throughput | no | no |
| TLS1_HUMAN | [view interactions] | High throughput | no | yes |
| TERA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PRKN_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HDAC6_HUMAN | [view interactions] | High throughput | no | yes |
| ZRAN1_HUMAN | [view interactions] | High throughput | no | yes |
| BAP1_HUMAN | [view interactions] | High throughput | no | yes |
| LOXL2_HUMAN | [view interactions] | High throughput | no | yes |
| HSP7C_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DX39B_HUMAN | [view interactions] | High throughput | no | no |
| ACE2_HUMAN | [view interactions] | High throughput | no | no |
| TRI67_HUMAN | [view interactions] | High throughput | no | no |
| UBP48_HUMAN | [view interactions] | High throughput | no | yes |
| FBXW7_HUMAN | [view interactions] | High throughput | no | yes |
| RHG24_HUMAN | [view interactions] | High throughput | no | yes |
| CFAH_HUMAN | [view interactions] | High throughput | no | no |
| EZH2_HUMAN | [view interactions] | High throughput | no | no |
| SPOP_HUMAN | [view interactions] | High throughput | no | no |
| RN207_HUMAN | [view interactions] | High throughput | no | no |
| RICTR_HUMAN | [view interactions] | High throughput | no | yes |
| UBE2H_HUMAN | [view interactions] | High throughput | no | yes |
| TNIP1_HUMAN | [view interactions] | High throughput | no | yes |
| ATG10_HUMAN | [view interactions] | High throughput | no | yes |
| ATG3_HUMAN | [view interactions] | High throughput | no | yes |
| EGFR_HUMAN | [view interactions] | High throughput | no | no |
| RASK_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RIT1_HUMAN | [view interactions] | High throughput | no | yes |
| ITA2B_HUMAN | [view interactions] | High throughput | no | no |
| TXD17_HUMAN | [view interactions] | High throughput | no | yes |
| UBE2K_HUMAN | [view interactions] | High throughput | no | yes |
| TYSY_HUMAN | [view interactions] | High throughput | no | yes |
| THIO_HUMAN | [view interactions] | High throughput | no | yes |
| RRP44_HUMAN | [view interactions] | High throughput | no | yes |
| UB2D1_HUMAN | [view interactions] | High throughput | no | yes |
| IF5A1_HUMAN | [view interactions] | High throughput | no | yes |
| CH10_HUMAN | [view interactions] | High throughput | no | yes |
| RBBP7_HUMAN | [view interactions] | High throughput | no | yes |
| CBX3_HUMAN | [view interactions] | High throughput | no | yes |
| MK14_HUMAN | [view interactions] | High throughput | no | yes |
| MVD1_HUMAN | [view interactions] | High throughput | no | yes |
| NAGK_HUMAN | [view interactions] | High throughput | no | no |
| NDKA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SCOT1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PTMS_HUMAN | [view interactions] | High throughput | no | yes |
| SMAP_HUMAN | [view interactions] | High throughput | no | yes |
| TALDO_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| THOP1_HUMAN | [view interactions] | High throughput | no | yes |
| RENR_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CALR_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| COF1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| COF2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DEST_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ENOA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ENOG_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AATC_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| G6PI_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GILT_HUMAN | [view interactions] | High throughput | no | no |
| ITPA_HUMAN | [view interactions] | High throughput | no | yes |
| LACB2_HUMAN | [view interactions] | High throughput | no | yes |
| LDHA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LDH6A_HUMAN | [view interactions] | High throughput | no | no |
| LDH6B_HUMAN | [view interactions] | High throughput | no | no |
| LDHB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LDHC_HUMAN | [view interactions] | High throughput | no | no |
| MSI2H_HUMAN | [view interactions] | High throughput | no | yes |
| NDKB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PABP4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PHS_HUMAN | [view interactions] | High throughput | no | yes |
| PPIH_HUMAN | [view interactions] | High throughput | no | yes |
| PRDX6_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PSMG4_HUMAN | [view interactions] | High throughput | no | yes |
| TKT_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CK054_HUMAN | [view interactions] | High throughput | no | no |
| CTBP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CGL_HUMAN | [view interactions] | High throughput | no | yes |
| EZRI_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| GALE_HUMAN | [view interactions] | High throughput | no | no |
| GGCT_HUMAN | [view interactions] | High throughput | no | yes |
| GMPPB_HUMAN | [view interactions] | High throughput | no | yes |
| GSTO2_HUMAN | [view interactions] | High throughput | no | no |
| MOES_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RGN_HUMAN | [view interactions] | High throughput | no | no |
| SCLY_HUMAN | [view interactions] | High throughput | no | yes |
| UAP1_HUMAN | [view interactions] | High throughput | no | yes |
| UAP1L_HUMAN | [view interactions] | High throughput | no | yes |
| HXK1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SYJ2B_HUMAN | [view interactions] | High throughput | no | no |
| CAP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SCFD1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ARBK1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MIPEP_HUMAN | [view interactions] | High throughput | no | yes |
| UBQL1_HUMAN | [view interactions] | High throughput | no | yes |
| SYFA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AGR2_HUMAN | [view interactions] | High throughput | no | no |
| NAA40_HUMAN | [view interactions] | High throughput | no | no |
| HS71B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HS71A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PHOCN_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RFA1_HUMAN | [view interactions] | High throughput | no | yes |
| RFA2_HUMAN | [view interactions] | High throughput | no | yes |
| RFA3_HUMAN | [view interactions] | High throughput | no | yes |