AATC_HUMAN
Evidence for PS localization
Functions
Biosynthesis of L-glutamate from L-aspartate or L-cysteine. Important regulator of levels of glutamate, the major excitatory neurotransmitter of the vertebrate central nervous system. Acts as a scavenger of glutamate in brain neuroprotection. The aspartate aminotransferase activity is involved in hepatic glucose synthesis during development and in adipocyte glyceroneogenesis. Using L-cysteine as substrate, regulates levels of mercaptopyruvate, an important source of hydrogen sulfide. Mercaptopyruvate is converted into H(2)S via the action of 3-mercaptopyruvate sulfurtransferase (3MST). Hydrogen sulfide is an important synaptic modulator and neuroprotectant in the brain. [View more on UniProt]
Protein features
Binary interactions with known binding regions
To display all evidence describing the interaction with a partner, click on the protein name left to the bars.
Network
Isoforms
Disease-causing germline mutations
No data found.
Linear motifs
No annotated instance was found. To search for linear motifs, use the ELM prediction server.
Fingerprint
Molecular function
| Term | Name | % | Distance from the top of the tree | Annotated in AATC_HUMAN |
|---|---|---|---|---|
| GO:0046872 | metal ion binding | 32.4074 | 4 | no |
| GO:0030170 | pyridoxal phosphate binding | 4.6296 | 4 | yes |
| GO:0004069 | L-aspartate:2-oxoglutarate aminotransferase activity | 2.7778 | 5 | yes |
| GO:0008483 | transaminase activity | 2.7778 | 4 | yes |
| GO:0016831 | carboxy-lyase activity | 2.7778 | 4 | yes |
| GO:0004609 | phosphatidylserine decarboxylase activity | 1.8519 | 5 | yes |
| GO:0047801 | L-cysteine transaminase activity | 1.8519 | 5 | yes |
Biological process
| Term | Name | % | Distance from top the of the tree | Annotated in AATC_HUMAN |
|---|---|---|---|---|
| GO:0048522 | positive regulation of cellular process | 41.6667 | 4 | no |
| GO:0048523 | negative regulation of cellular process | 33.3333 | 4 | no |
| GO:0010646 | regulation of cell communication | 33.3333 | 4 | no |
| GO:0019752 | carboxylic acid metabolic process | 30.5556 | 5 | yes |
| GO:0043436 | oxoacid metabolic process | 30.5556 | 4 | yes |
| GO:0060255 | regulation of macromolecule metabolic process | 28.7037 | 4 | no |
| GO:0080090 | regulation of primary metabolic process | 27.7778 | 4 | no |
| GO:0022607 | cellular component assembly | 26.8519 | 4 | no |
| GO:0051128 | regulation of cellular component organization | 26.8519 | 4 | no |
| GO:0009966 | regulation of signal transduction | 26.8519 | 4 | no |
| GO:0051171 | regulation of nitrogen compound metabolic process | 26.8519 | 4 | no |
| GO:0006996 | organelle organization | 25.9259 | 4 | no |
| GO:0031323 | regulation of cellular metabolic process | 25.9259 | 4 | no |
| GO:0008104 | protein localization | 24.0741 | 4 | no |
| GO:0051049 | regulation of transport | 24.0741 | 4 | no |
| GO:0051246 | regulation of protein metabolic process | 21.2963 | 5 | no |
| GO:0009893 | positive regulation of metabolic process | 20.3704 | 4 | no |
| GO:1901566 | organonitrogen compound biosynthetic process | 16.6667 | 4 | yes |
| GO:0043648 | dicarboxylic acid metabolic process | 14.8148 | 6 | yes |
| GO:0071310 | cellular response to organic substance | 14.8148 | 4 | yes |
| GO:0014070 | response to organic cyclic compound | 11.1111 | 4 | yes |
| GO:1901701 | cellular response to oxygen-containing compound | 11.1111 | 4 | yes |
| GO:0033993 | response to lipid | 10.1852 | 4 | yes |
| GO:1901605 | alpha-amino acid metabolic process | 10.1852 | 4 | yes |
| GO:0010243 | response to organonitrogen compound | 9.2593 | 4 | yes |
| GO:0016053 | organic acid biosynthetic process | 9.2593 | 4 | yes |
| GO:0016054 | organic acid catabolic process | 9.2593 | 4 | yes |
| GO:0046394 | carboxylic acid biosynthetic process | 9.2593 | 5 | yes |
| GO:0046395 | carboxylic acid catabolic process | 9.2593 | 5 | yes |
| GO:1901565 | organonitrogen compound catabolic process | 9.2593 | 4 | yes |
| GO:0009064 | glutamine family amino acid metabolic process | 8.3333 | 5 | yes |
| GO:0008652 | cellular amino acid biosynthetic process | 7.4074 | 4 | yes |
| GO:0009063 | cellular amino acid catabolic process | 7.4074 | 4 | yes |
| GO:0048878 | chemical homeostasis | 7.4074 | 4 | yes |
| GO:1901606 | alpha-amino acid catabolic process | 7.4074 | 5 | yes |
| GO:1901607 | alpha-amino acid biosynthetic process | 7.4074 | 5 | yes |
| GO:0006103 | 2-oxoglutarate metabolic process | 6.4815 | 7 | yes |
| GO:0006536 | glutamate metabolic process | 6.4815 | 6 | yes |
| GO:0016051 | carbohydrate biosynthetic process | 6.4815 | 4 | yes |
| GO:0071417 | cellular response to organonitrogen compound | 6.4815 | 4 | yes |
| GO:1901699 | cellular response to nitrogen compound | 6.4815 | 4 | yes |
| GO:0006107 | oxaloacetate metabolic process | 5.5556 | 7 | yes |
| GO:0009065 | glutamine family amino acid catabolic process | 5.5556 | 6 | yes |
| GO:0006538 | glutamate catabolic process | 4.6296 | 5 | yes |
| GO:0009066 | aspartate family amino acid metabolic process | 4.6296 | 5 | yes |
| GO:0032870 | cellular response to hormone stimulus | 4.6296 | 4 | yes |
| GO:0043649 | dicarboxylic acid catabolic process | 4.6296 | 6 | yes |
| GO:0043650 | dicarboxylic acid biosynthetic process | 4.6296 | 6 | yes |
| GO:0048545 | response to steroid hormone | 4.6296 | 4 | yes |
| GO:1901652 | response to peptide | 4.6296 | 4 | yes |
| GO:0006106 | fumarate metabolic process | 3.7037 | 7 | yes |
| GO:0043434 | response to peptide hormone | 3.7037 | 4 | yes |
| GO:0046165 | alcohol biosynthetic process | 3.7037 | 4 | yes |
| GO:1901617 | organic hydroxy compound biosynthetic process | 3.7037 | 4 | yes |
| GO:0006071 | glycerol metabolic process | 2.7778 | 5 | yes |
| GO:0006531 | aspartate metabolic process | 2.7778 | 6 | yes |
| GO:0006532 | aspartate biosynthetic process | 2.7778 | 7 | yes |
| GO:0006533 | aspartate catabolic process | 2.7778 | 5 | yes |
| GO:0009067 | aspartate family amino acid biosynthetic process | 2.7778 | 6 | yes |
| GO:0009068 | aspartate family amino acid catabolic process | 2.7778 | 6 | yes |
| GO:0019400 | alditol metabolic process | 2.7778 | 4 | yes |
| GO:0019550 | glutamate catabolic process to aspartate | 2.7778 | 6 | yes |
| GO:0019551 | glutamate catabolic process to 2-oxoglutarate | 2.7778 | 6 | yes |
| GO:0019751 | polyol metabolic process | 2.7778 | 4 | yes |
| GO:0031960 | response to corticosteroid | 2.7778 | 5 | yes |
| GO:0051384 | response to glucocorticoid | 2.7778 | 6 | yes |
| GO:1901653 | cellular response to peptide | 2.7778 | 5 | yes |
| GO:0006114 | glycerol biosynthetic process | 1.8519 | 6 | yes |
| GO:0007219 | Notch signaling pathway | 1.8519 | 4 | yes |
| GO:0019401 | alditol biosynthetic process | 1.8519 | 5 | yes |
| GO:0032868 | response to insulin | 1.8519 | 5 | yes |
| GO:0032869 | cellular response to insulin stimulus | 1.8519 | 6 | yes |
| GO:0034637 | cellular carbohydrate biosynthetic process | 1.8519 | 4 | yes |
| GO:0046173 | polyol biosynthetic process | 1.8519 | 5 | yes |
| GO:0055088 | lipid homeostasis | 1.8519 | 5 | yes |
| GO:0055089 | fatty acid homeostasis | 1.8519 | 6 | yes |
| GO:0071375 | cellular response to peptide hormone stimulus | 1.8519 | 5 | yes |
Disease
| Term | Name | % | Distance from top the of the tree | Annotated in AATC_HUMAN |
|---|---|---|---|---|
| DOID:0050155 | sensory system disease | 1.8519 | 3 | no |
| DOID:10584 | retinitis pigmentosa | 1.8519 | 7 | no |
| DOID:5614 | eye disease | 1.8519 | 4 | no |
| DOID:8466 | retinal degeneration | 1.8519 | 6 | no |
| DOID:9799 | eye degenerative disease | 1.8519 | 5 | no |
| DOID:37 | skin disease | 1.8519 | 3 | no |
| DOID:0050700 | cardiomyopathy | 1.8519 | 4 | no |
| DOID:0060036 | intrinsic cardiomyopathy | 1.8519 | 5 | no |
| DOID:114 | heart disease | 1.8519 | 3 | no |
| DOID:0080000 | muscular disease | 1.8519 | 3 | no |
| DOID:0110274 | autosomal recessive limb-girdle muscular dystrophy | 1.8519 | 8 | no |
| DOID:11724 | limb-girdle muscular dystrophy | 1.8519 | 7 | no |
| DOID:423 | myopathy | 1.8519 | 5 | no |
| DOID:66 | muscle tissue disease | 1.8519 | 4 | no |
| DOID:9884 | muscular dystrophy | 1.8519 | 6 | no |
All partners
| Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
|---|---|---|---|---|
| PYC_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| AATC_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| AHNK2_HUMAN | [view interactions] | High throughput | no | yes |
| TMM40_HUMAN | [view interactions] | High throughput | no | no |
| ARF5_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| TT39B_HUMAN | [view interactions] | High throughput | no | no |
| CD9_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| SPB8_HUMAN | [view interactions] | High throughput | no | no |
| TGM5_HUMAN | [view interactions] | High throughput | no | no |
| VPS35_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| OSTF1_HUMAN | [view interactions] | High throughput | no | yes |
| CALL3_HUMAN | [view interactions] | High throughput | no | yes |
| CADH1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CLIC3_HUMAN | [view interactions] | High throughput | no | no |
| ANXA8_HUMAN | [view interactions] | High throughput | no | no |
| DSG3_HUMAN | [view interactions] | High throughput | no | no |
| NFH_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| APOA1_HUMAN | [view interactions] | High throughput | no | no |
| DSG1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| PEPL_HUMAN | [view interactions] | High throughput | no | yes |
| PSME2_HUMAN | [view interactions] | High throughput | no | no |
| KCY_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HMCS1_HUMAN | [view interactions] | High throughput | no | yes |
| DMKN_HUMAN | [view interactions] | High throughput | no | no |
| FCL_HUMAN | [view interactions] | High throughput | no | yes |
| TPPP3_HUMAN | [view interactions] | High throughput | no | no |
| SPB3_HUMAN | [view interactions] | High throughput | no | no |
| DR9C7_HUMAN | [view interactions] | High throughput | no | no |
| IL1RA_HUMAN | [view interactions] | High throughput | no | no |
| ALBU_HUMAN | [view interactions] | High throughput | no | no |
| HEM2_HUMAN | [view interactions] | High throughput | no | no |
| AL3A1_HUMAN | [view interactions] | High throughput | no | no |
| PAI2_HUMAN | [view interactions] | High throughput | no | no |
| NB5R3_HUMAN | [view interactions] | High throughput | no | yes |
| RHG01_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ES8L2_HUMAN | [view interactions] | High throughput | no | yes |
| SPB5_HUMAN | [view interactions] | High throughput | no | no |
| TGM1_HUMAN | [view interactions] | High throughput | no | no |
| TGM3_HUMAN | [view interactions] | High throughput | no | no |
| OTU1_HUMAN | [view interactions] | High throughput | no | yes |
| TRFL_HUMAN | [view interactions] | High throughput | no | no |
| NECP2_HUMAN | [view interactions] | High throughput | no | yes |
| LAD1_HUMAN | [view interactions] | High throughput | no | no |
| KPYM_HUMAN | [view interactions] | High throughput | no | yes |
| PKP1_HUMAN | [view interactions] | High throughput | no | no |
| I36RA_HUMAN | [view interactions] | High throughput | no | no |
| RABP2_HUMAN | [view interactions] | High throughput | no | no |
| PPAP_HUMAN | [view interactions] | High throughput | no | no |
| FBX50_HUMAN | [view interactions] | High throughput | no | no |
| TRI29_HUMAN | [view interactions] | High throughput | no | no |
| CO3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RAB25_HUMAN | [view interactions] | High throughput | no | no |
| RDHE2_HUMAN | [view interactions] | High throughput | no | yes |
| MVP_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GAN_HUMAN | [view interactions] | High throughput | no | yes |
| ELOV4_HUMAN | [view interactions] | High throughput | no | no |
| DESP_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| PA24D_HUMAN | [view interactions] | High throughput | no | no |
| AK1C2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| TREX2_HUMAN | [view interactions] | High throughput | no | no |
| ACADV_HUMAN | [view interactions] | High throughput | no | yes |
| THIK_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SYNC_HUMAN | [view interactions] | High throughput | no | yes |
| POF1B_HUMAN | [view interactions] | High throughput | no | no |
| FIBB_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| FIBA_HUMAN | [view interactions] | High throughput | no | no |
| MARE2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| S1A7A_HUMAN | [view interactions] | High throughput | no | no |
| XDH_HUMAN | [view interactions] | High throughput | no | no |
| TYPH_HUMAN | [view interactions] | High throughput | no | no |
| KLK10_HUMAN | [view interactions] | High throughput | no | no |
| LEG3_HUMAN | [view interactions] | High throughput | no | yes |
| DUS14_HUMAN | [view interactions] | High throughput | no | yes |
| ICAL_HUMAN | [view interactions] | High throughput | no | yes |
| ZO2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| SQOR_HUMAN | [view interactions] | High throughput | no | yes |
| PGM2_HUMAN | [view interactions] | High throughput | no | no |
| CLIP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RAB14_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TRFE_HUMAN | [view interactions] | High throughput | no | no |
| HUTH_HUMAN | [view interactions] | High throughput | no | yes |
| CD44_HUMAN | [view interactions] | High throughput | no | yes |
| NDRG1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TNAP2_HUMAN | [view interactions] | High throughput | no | no |
| RBBP9_HUMAN | [view interactions] | High throughput | no | yes |
| SPB4_HUMAN | [view interactions] | High throughput | no | no |
| HMOX1_HUMAN | [view interactions] | High throughput | no | no |
| ANXA1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| TAU_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ANXA6_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CHRC1_HUMAN | [view interactions] | High throughput | no | no |
| HPRT_HUMAN | [view interactions] | High throughput | no | yes |
| IDHC_HUMAN | [view interactions] | High throughput | no | no |
| MTAP_HUMAN | [view interactions] | High throughput | no | no |
| SBDS_HUMAN | [view interactions] | High throughput | no | yes |
| TYSY_HUMAN | [view interactions] | High throughput | no | yes |
| UBE2H_HUMAN | [view interactions] | High throughput | no | yes |
| PPAC_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ANX11_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CK054_HUMAN | [view interactions] | High throughput | no | no |
| CBR1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CCS_HUMAN | [view interactions] | High throughput | no | yes |
| FAHD1_HUMAN | [view interactions] | High throughput | no | yes |
| GLOD4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AL4A1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AL7A1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CRIP1_HUMAN | [view interactions] | High throughput | no | yes |
| DCXR_HUMAN | [view interactions] | High throughput | no | no |
| FUMH_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LYAG_HUMAN | [view interactions] | High throughput | no | yes |
| ALAT2_HUMAN | [view interactions] | High throughput | no | yes |
| HTRA2_HUMAN | [view interactions] | High throughput | no | yes |
| KIF2C_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| NDKB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| OAT_HUMAN | [view interactions] | High throughput | no | yes |
| PDC6I_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PEPD_HUMAN | [view interactions] | High throughput | no | yes |
| SERA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PIR_HUMAN | [view interactions] | High throughput | no | no |
| PTGR1_HUMAN | [view interactions] | High throughput | no | yes |
| RAE1L_HUMAN | [view interactions] | High throughput | no | no |
| SODC_HUMAN | [view interactions] | High throughput | no | yes |
| WDR1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| WDR82_HUMAN | [view interactions] | High throughput | no | no |
| YKT6_HUMAN | [view interactions] | High throughput | no | yes |
| CH10_HUMAN | [view interactions] | High throughput | no | yes |
| NQO1_HUMAN | [view interactions] | High throughput | no | no |
| PIPNA_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| PIPNB_HUMAN | [view interactions] | High throughput | no | no |
| PPIL3_HUMAN | [view interactions] | High throughput | no | yes |
| RIFK_HUMAN | [view interactions] | High throughput | no | yes |
| DLG4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SNX3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| AATC2_HUMAN | [view interactions] | High throughput | no | no |
| SRXN1_HUMAN | [view interactions] | High throughput | no | no |
| GRB2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TALDO_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| NTM2F_HUMAN | [view interactions] | High throughput | no | no |
| TPIS_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DAG1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| UFM1_HUMAN | [view interactions] | High throughput | no | yes |
| RL6_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ENOG_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TRI63_HUMAN | [view interactions] | High throughput | no | no |
| AADAT_HUMAN | [view interactions] | High throughput | no | no |
| CAH2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ASPG_HUMAN | [view interactions] | High throughput | no | yes |
| HBA_HUMAN | [view interactions] | High throughput | no | no |
| MIA40_HUMAN | [view interactions] | High throughput | no | yes |
| MDHC_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ECHM_HUMAN | [view interactions] | High throughput | no | yes |
| NDKA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KAT3_HUMAN | [view interactions] | High throughput | no | yes |
| PRDX1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MCFD2_HUMAN | [view interactions] | High throughput | no | yes |
| PRDX2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SCOT1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ALDR_HUMAN | [view interactions] | High throughput | no | no |
| 6PGD_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| AMRP_HUMAN | [view interactions] | High throughput | no | yes |
| TRAP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HEBP1_HUMAN | [view interactions] | High throughput | no | yes |
| TRXR2_HUMAN | [view interactions] | High throughput | no | yes |
| KAD3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TYK2_HUMAN | [view interactions] | High throughput | no | no |
| SIAS_HUMAN | [view interactions] | High throughput | no | yes |
| GSHR_HUMAN | [view interactions] | High throughput | no | yes |
| UBE2N_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PYRD_HUMAN | [view interactions] | High throughput | no | yes |
| UBB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CMC1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| UBC_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NDUS3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RS27A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ACTN2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RL40_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TNIK_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HLAB_HUMAN | [view interactions] | High throughput | no | yes |
| KCMA1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| KCNQ1_HUMAN | [view interactions] | High throughput | no | yes |
| CAV3_HUMAN | [view interactions] | High throughput | no | no |
| RYR2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TARSH_HUMAN | [view interactions] | High throughput | no | no |
| TACAN_HUMAN | [view interactions] | High throughput | no | no |
| SHAN3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| EGFR_HUMAN | [view interactions] | High throughput | no | no |
| AGTR1_HUMAN | [view interactions] | High throughput | no | no |
| CCR2_HUMAN | [view interactions] | High throughput | no | yes |
| GLYM_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MOV10_HUMAN | [view interactions] | High throughput | no | no |
| NXF1_HUMAN | [view interactions] | High throughput | no | yes |
| HNRPK_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ESR2_HUMAN | [view interactions] | High throughput | no | no |
| NEB2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TIA1_HUMAN | [view interactions] | High throughput | no | no |
| RBM39_HUMAN | [view interactions] | High throughput | no | yes |
| CUL4A_HUMAN | [view interactions] | High throughput | no | no |
| DDX58_HUMAN | [view interactions] | High throughput | no | yes |
| UBQL1_HUMAN | [view interactions] | High throughput | no | yes |
| EZRI_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ATLA3_HUMAN | [view interactions] | High throughput | no | no |
| IL36G_HUMAN | [view interactions] | High throughput | no | no |
| S10AE_HUMAN | [view interactions] | High throughput | no | no |
| LEG7_HUMAN | [view interactions] | High throughput | no | no |
| CRBG1_HUMAN | [view interactions] | High throughput | no | no |
| PLSL_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ASC_HUMAN | [view interactions] | High throughput | no | no |
| PLBL1_HUMAN | [view interactions] | High throughput | no | no |
| PLEC_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CAPG_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| INVO_HUMAN | [view interactions] | High throughput | no | no |
| ITPR3_HUMAN | [view interactions] | High throughput | no | yes |
| NAGK_HUMAN | [view interactions] | High throughput | no | no |
| ENDOU_HUMAN | [view interactions] | High throughput | no | no |
| KI13B_HUMAN | [view interactions] | High throughput | no | yes |
| CALL5_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| LX12B_HUMAN | [view interactions] | High throughput | no | no |
| S10A7_HUMAN | [view interactions] | High throughput | no | no |
| H2AY_HUMAN | [view interactions] | High throughput | no | yes |
| H15_HUMAN | [view interactions] | High throughput | no | no |
| STEA4_HUMAN | [view interactions] | High throughput | no | no |
| BIEA_HUMAN | [view interactions] | High throughput | no | yes |
| BLVRB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TAP1_HUMAN | [view interactions] | High throughput | no | yes |
| GSDMA_HUMAN | [view interactions] | High throughput | no | no |
| PLIN3_HUMAN | [view interactions] | High throughput | no | yes |
| PLMN_HUMAN | [view interactions] | High throughput | no | no |
| QSOX1_HUMAN | [view interactions] | High throughput | no | no |
| DBNL_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ZN185_HUMAN | [view interactions] | High throughput | no | no |
| S100P_HUMAN | [view interactions] | High throughput | no | no |
| S10A9_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CFAH_HUMAN | [view interactions] | High throughput | no | no |
| FA83H_HUMAN | [view interactions] | High throughput | no | yes |
| GUAD_HUMAN | [view interactions] | High throughput | no | yes |
| AK1BA_HUMAN | [view interactions] | High throughput | no | no |
| ICAM1_HUMAN | [view interactions] | High throughput | no | no |
| THRB_HUMAN | [view interactions] | High throughput | no | no |
| FIBG_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| EMAL2_HUMAN | [view interactions] | High throughput | no | yes |
| MACF1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CBPA4_HUMAN | [view interactions] | High throughput | no | no |
| SPB7_HUMAN | [view interactions] | High throughput | no | no |
| SNG2_HUMAN | [view interactions] | High throughput | no | no |
| FCSD1_HUMAN | [view interactions] | High throughput | no | yes |
| CDSN_HUMAN | [view interactions] | High throughput | no | no |
| CASPE_HUMAN | [view interactions] | High throughput | no | no |
| IQGA1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| PMVK_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| 5NT3A_HUMAN | [view interactions] | High throughput | no | yes |
| CATL2_HUMAN | [view interactions] | High throughput | no | yes |
| EVPL_HUMAN | [view interactions] | High throughput | no | yes |
| CPNS2_HUMAN | [view interactions] | High throughput | no | no |
| ANR22_HUMAN | [view interactions] | High throughput | no | no |
| ILEU_HUMAN | [view interactions] | High throughput | no | no |
| GELS_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| IL36A_HUMAN | [view interactions] | High throughput | no | no |
| PKP3_HUMAN | [view interactions] | High throughput | no | yes |
| S10A8_HUMAN | [view interactions] | High throughput | no | no |
| TXNL1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NIBA2_HUMAN | [view interactions] | High throughput | no | no |
| FILA_HUMAN | [view interactions] | High throughput | no | no |
| PI42C_HUMAN | [view interactions] | High throughput | no | yes |
| DDAH2_HUMAN | [view interactions] | High throughput | no | yes |
| EPIPL_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| SBSN_HUMAN | [view interactions] | High throughput | no | no |
| PLAK_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| IGLL5_HUMAN | [view interactions] | High throughput | no | no |
| ST2B1_HUMAN | [view interactions] | High throughput | no | yes |
| DSC2_HUMAN | [view interactions] | High throughput | no | no |
| PA24B_HUMAN | [view interactions] | High throughput | no | no |
| STA10_HUMAN | [view interactions] | High throughput | no | yes |
| AACT_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| 1433S_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| H2A1_HUMAN | [view interactions] | High throughput | no | yes |
| RAB5A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RAB5B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AL1A3_HUMAN | [view interactions] | High throughput | no | yes |
| CO4A_HUMAN | [view interactions] | High throughput | no | no |
| IDH3A_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| PH4H_HUMAN | [view interactions] | Computational | no | no |
| IDH3B_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| GADL1_HUMAN | [view interactions] | Computational | no | no |
| ESTD_HUMAN | [view interactions] | Computational | no | yes |
| MDHM_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| PURA1_HUMAN | [view interactions] | Computational | no | no |
| LDHB_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| AMPN_HUMAN | [view interactions] | Computational | no | no |
| OXLA_HUMAN | [view interactions] | Computational | no | no |
| MIF_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| DCE1_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| ACLY_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| MMSA_HUMAN | [view entry] [view interactions] | Computational | yes | no |
| TY3H_HUMAN | [view interactions] | Computational | no | no |
| ALAT1_HUMAN | [view interactions] | Computational | no | no |
| LPP60_HUMAN | [view interactions] | Computational | no | yes |
| ASNS_HUMAN | [view interactions] | Computational | no | yes |
| PYR1_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| LDHC_HUMAN | [view interactions] | Computational | no | no |
| LDH6B_HUMAN | [view interactions] | Computational | no | no |
| CDO1_HUMAN | [view interactions] | Computational | no | no |
| ASPD_HUMAN | [view interactions] | Computational | no | yes |
| LDHA_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| DCE2_HUMAN | [view interactions] | Computational | no | yes |
| IDHP_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| AATM_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| THTM_HUMAN | [view interactions] | Computational | no | yes |
| NAGS_HUMAN | [view interactions] | Computational | no | no |
| PCKGC_HUMAN | [view interactions] | Computational | no | no |
| IDH3G_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| OGDHL_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| GSH0_HUMAN | [view interactions] | Computational | no | yes |
| ASGL1_HUMAN | [view interactions] | Computational | no | yes |
| ACY2_HUMAN | [view interactions] | Computational | no | no |
| HOGA1_HUMAN | [view interactions] | Computational | no | yes |
| LDH6A_HUMAN | [view interactions] | Computational | no | no |
| AMPL_HUMAN | [view entry] [view interactions] | Computational | yes | no |
| CISY_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| PPCS_HUMAN | [view interactions] | Computational | no | yes |
| GGCT_HUMAN | [view interactions] | Computational | no | yes |
| PERT_HUMAN | [view interactions] | Computational | no | no |
| ODO1_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| NAT8L_HUMAN | [view interactions] | Computational | no | no |
| PURA2_HUMAN | [view interactions] | Computational | no | yes |
| THTR_HUMAN | [view interactions] | Computational | no | yes |
| ASSY_HUMAN | [view interactions] | Computational | no | yes |
| PCKGM_HUMAN | [view interactions] | Computational | no | no |
| FTCD_HUMAN | [view interactions] | Computational | no | no |
| DDC_HUMAN | [view interactions] | Computational | no | no |
| NIT2_HUMAN | [view interactions] | Computational | no | yes |
| CGL_HUMAN | [view interactions] | Computational | no | yes |
| DHE3_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| CSAD_HUMAN | [view interactions] | Computational | no | yes |
| ATTY_HUMAN | [view interactions] | Computational | no | no |
| TYRO_HUMAN | [view interactions] | Computational | no | no |
| DHE4_HUMAN | [view interactions] | Computational | no | yes |