SNX3_HUMAN
Evidence for PS localization
Functions
Phosphoinositide-binding protein required for multivesicular body formation. Specifically binds phosphatidylinositol 3-phosphate (PtdIns(P3)). Also can bind phosphatidylinositol 4-phosphate (PtdIns(P4)), phosphatidylinositol 5-phosphate (PtdIns(P5)) and phosphatidylinositol 3,5-biphosphate (PtdIns(3,5)P2) . Plays a role in protein transport between cellular compartments. Together with RAB7A facilitates endosome membrane association of the retromer cargo-selective subcomplex (CSC/VPS). May in part act as component of the SNX3-retromer complex which mediates the retrograde endosome-to-TGN transport of WLS distinct from the SNX-BAR retromer pathway (PubMed, PubMed, PubMed). Promotes stability and cell surface expression of epithelial sodium channel (ENAC) subunits SCNN1A and SCNN1G . Not involved in EGFR degradation. Involved in the regulation of phagocytosis in dendritic cells possibly by regulating EEA1 recruitment to the nascent phagosomes (PubMed). Involved in iron homeostasis through regulation of endocytic recycling of the transferrin receptor TFRC presumably by delivering the transferrin:transferrin receptor complex to recycling endosomes; the function may involve the CSC retromer subcomplex . In the case of Salmonella enterica infection plays arole in maturation of the Salmonella-containing vacuole (SCV) and promotes recruitment of LAMP1 to SCVs (PubMed). [View more on UniProt]
Protein features
Binary interactions with known binding regions
To display all evidence describing the interaction with a partner, click on the protein name left to the bars.
Network
Isoforms
Disease-causing germline mutations
No data found.
Linear motifs
No annotated instance was found. To search for linear motifs, use the ELM prediction server.
Fingerprint
Molecular function
| Term | Name | % | Distance from the top of the tree | Annotated in SNX3_HUMAN |
|---|---|---|---|---|
| GO:0043168 | anion binding | 37.8378 | 4 | yes |
| GO:0000166 | nucleotide binding | 25.6757 | 4 | no |
| GO:0017076 | purine nucleotide binding | 25.6757 | 5 | no |
| GO:0032555 | purine ribonucleotide binding | 25.6757 | 4 | no |
| GO:0035639 | purine ribonucleoside triphosphate binding | 25.6757 | 4 | no |
| GO:0035091 | phosphatidylinositol binding | 16.2162 | 4 | yes |
| GO:1901981 | phosphatidylinositol phosphate binding | 6.7568 | 5 | yes |
| GO:0019902 | phosphatase binding | 5.4054 | 4 | yes |
| GO:0019903 | protein phosphatase binding | 5.4054 | 5 | yes |
| GO:0032266 | phosphatidylinositol-3-phosphate binding | 4.0541 | 6 | yes |
| GO:1902936 | phosphatidylinositol bisphosphate binding | 4.0541 | 6 | yes |
| GO:0010314 | phosphatidylinositol-5-phosphate binding | 2.7027 | 6 | yes |
| GO:0070273 | phosphatidylinositol-4-phosphate binding | 2.7027 | 6 | yes |
| GO:0080025 | phosphatidylinositol-3,5-bisphosphate binding | 2.7027 | 5 | yes |
Biological process
| Term | Name | % | Distance from top the of the tree | Annotated in SNX3_HUMAN |
|---|---|---|---|---|
| GO:0048522 | positive regulation of cellular process | 55.4054 | 4 | yes |
| GO:0008104 | protein localization | 50.0000 | 4 | yes |
| GO:0048523 | negative regulation of cellular process | 44.5946 | 4 | yes |
| GO:0060255 | regulation of macromolecule metabolic process | 43.2432 | 4 | yes |
| GO:0010646 | regulation of cell communication | 41.8919 | 4 | yes |
| GO:0071702 | organic substance transport | 41.8919 | 4 | yes |
| GO:0031323 | regulation of cellular metabolic process | 41.8919 | 4 | no |
| GO:0071705 | nitrogen compound transport | 40.5405 | 4 | yes |
| GO:0080090 | regulation of primary metabolic process | 40.5405 | 4 | yes |
| GO:0051128 | regulation of cellular component organization | 39.1892 | 4 | yes |
| GO:0009966 | regulation of signal transduction | 37.8378 | 4 | yes |
| GO:0015031 | protein transport | 37.8378 | 4 | yes |
| GO:0006996 | organelle organization | 36.4865 | 4 | yes |
| GO:0051049 | regulation of transport | 33.7838 | 4 | yes |
| GO:0009889 | regulation of biosynthetic process | 33.7838 | 4 | no |
| GO:0060341 | regulation of cellular localization | 32.4324 | 4 | yes |
| GO:0022607 | cellular component assembly | 32.4324 | 4 | no |
| GO:0032880 | regulation of protein localization | 31.0811 | 5 | yes |
| GO:0051246 | regulation of protein metabolic process | 31.0811 | 5 | yes |
| GO:0009893 | positive regulation of metabolic process | 31.0811 | 4 | no |
| GO:0010468 | regulation of gene expression | 31.0811 | 6 | no |
| GO:0010556 | regulation of macromolecule biosynthetic process | 31.0811 | 5 | no |
| GO:0031326 | regulation of cellular biosynthetic process | 31.0811 | 5 | no |
| GO:0009894 | regulation of catabolic process | 28.3784 | 4 | yes |
| GO:0010604 | positive regulation of macromolecule metabolic process | 28.3784 | 5 | no |
| GO:0009892 | negative regulation of metabolic process | 27.0270 | 4 | yes |
| GO:0031325 | positive regulation of cellular metabolic process | 27.0270 | 5 | no |
| GO:0033043 | regulation of organelle organization | 27.0270 | 5 | no |
| GO:0006886 | intracellular protein transport | 27.0270 | 4 | no |
| GO:0010605 | negative regulation of macromolecule metabolic process | 25.6757 | 5 | yes |
| GO:0048584 | positive regulation of response to stimulus | 25.6757 | 4 | no |
| GO:0051130 | positive regulation of cellular component organization | 24.3243 | 5 | yes |
| GO:0010647 | positive regulation of cell communication | 24.3243 | 5 | no |
| GO:0019219 | regulation of nucleobase-containing compound metabolic process | 24.3243 | 5 | no |
| GO:0023056 | positive regulation of signaling | 24.3243 | 4 | no |
| GO:1902531 | regulation of intracellular signal transduction | 24.3243 | 5 | no |
| GO:0031324 | negative regulation of cellular metabolic process | 22.9730 | 5 | no |
| GO:0042981 | regulation of apoptotic process | 22.9730 | 5 | no |
| GO:0043067 | regulation of programmed cell death | 22.9730 | 4 | no |
| GO:0044087 | regulation of cellular component biogenesis | 22.9730 | 4 | no |
| GO:0048585 | negative regulation of response to stimulus | 22.9730 | 4 | no |
| GO:0060627 | regulation of vesicle-mediated transport | 21.6216 | 4 | yes |
| GO:0009891 | positive regulation of biosynthetic process | 21.6216 | 5 | no |
| GO:0009967 | positive regulation of signal transduction | 21.6216 | 5 | no |
| GO:0043066 | negative regulation of apoptotic process | 21.6216 | 6 | no |
| GO:0043069 | negative regulation of programmed cell death | 21.6216 | 5 | no |
| GO:0051050 | positive regulation of transport | 21.6216 | 4 | no |
| GO:0016482 | cytosolic transport | 20.2703 | 4 | yes |
| GO:0010557 | positive regulation of macromolecule biosynthetic process | 20.2703 | 6 | no |
| GO:0019220 | regulation of phosphate metabolic process | 20.2703 | 6 | no |
| GO:0031328 | positive regulation of cellular biosynthetic process | 20.2703 | 6 | no |
| GO:0031399 | regulation of protein modification process | 20.2703 | 6 | no |
| GO:0051174 | regulation of phosphorus metabolic process | 20.2703 | 5 | no |
| GO:0051247 | positive regulation of protein metabolic process | 20.2703 | 6 | no |
| GO:0051252 | regulation of RNA metabolic process | 20.2703 | 5 | no |
| GO:0031344 | regulation of cell projection organization | 18.9189 | 5 | yes |
| GO:0042147 | retrograde transport, endosome to Golgi | 18.9189 | 4 | yes |
| GO:0051248 | negative regulation of protein metabolic process | 18.9189 | 6 | yes |
| GO:0070201 | regulation of establishment of protein localization | 18.9189 | 6 | yes |
| GO:0120035 | regulation of plasma membrane bounded cell projection organization | 18.9189 | 6 | yes |
| GO:0042176 | regulation of protein catabolic process | 14.8649 | 5 | yes |
| GO:0051129 | negative regulation of cellular component organization | 14.8649 | 5 | yes |
| GO:0051223 | regulation of protein transport | 14.8649 | 5 | yes |
| GO:0030100 | regulation of endocytosis | 13.5135 | 5 | yes |
| GO:0032456 | endocytic recycling | 13.5135 | 4 | yes |
| GO:0030111 | regulation of Wnt signaling pathway | 12.1622 | 5 | yes |
| GO:0031346 | positive regulation of cell projection organization | 12.1622 | 6 | yes |
| GO:0009895 | negative regulation of catabolic process | 10.8108 | 5 | yes |
| GO:0016050 | vesicle organization | 10.8108 | 5 | yes |
| GO:0032386 | regulation of intracellular transport | 10.8108 | 5 | yes |
| GO:0051051 | negative regulation of transport | 10.8108 | 4 | yes |
| GO:0010975 | regulation of neuron projection development | 9.4595 | 7 | yes |
| GO:0061024 | membrane organization | 9.4595 | 4 | yes |
| GO:1903828 | negative regulation of protein localization | 9.4595 | 5 | yes |
| GO:0010976 | positive regulation of neuron projection development | 8.1081 | 7 | yes |
| GO:0042177 | negative regulation of protein catabolic process | 8.1081 | 6 | yes |
| GO:0007032 | endosome organization | 6.7568 | 6 | yes |
| GO:0032387 | negative regulation of intracellular transport | 5.4054 | 5 | yes |
| GO:0045806 | negative regulation of endocytosis | 5.4054 | 5 | yes |
| GO:0051224 | negative regulation of protein transport | 5.4054 | 5 | yes |
| GO:1903900 | regulation of viral life cycle | 5.4054 | 4 | yes |
| GO:1904950 | negative regulation of establishment of protein localization | 5.4054 | 6 | yes |
| GO:2000641 | regulation of early endosome to late endosome transport | 5.4054 | 5 | yes |
| GO:0010324 | membrane invagination | 4.0541 | 5 | yes |
| GO:0034499 | late endosome to Golgi transport | 4.0541 | 4 | yes |
| GO:0046596 | regulation of viral entry into host cell | 4.0541 | 5 | yes |
| GO:0048525 | negative regulation of viral process | 4.0541 | 4 | yes |
| GO:0050764 | regulation of phagocytosis | 4.0541 | 6 | yes |
| GO:0050765 | negative regulation of phagocytosis | 4.0541 | 6 | yes |
| GO:0052372 | modulation by symbiont of entry into host | 4.0541 | 4 | yes |
| GO:1903901 | negative regulation of viral life cycle | 4.0541 | 5 | yes |
| GO:2000642 | negative regulation of early endosome to late endosome transport | 4.0541 | 6 | yes |
| GO:0006900 | vesicle budding from membrane | 2.7027 | 5 | yes |
| GO:0046597 | negative regulation of viral entry into host cell | 2.7027 | 6 | yes |
| GO:0070676 | intralumenal vesicle formation | 2.7027 | 6 | yes |
Disease
No data found.
All partners
| Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
|---|---|---|---|---|
| VPS35_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| SCNNA_HUMAN | [view interactions] | Low throughput | no | yes |
| VP26A_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| RAB7A_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| UBP10_HUMAN | [view interactions] | Low throughput | no | yes |
| NRAM2_HUMAN | [view interactions] | Low throughput | no | yes |
| SNX3_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| CFTR_HUMAN | [view interactions] | High throughput | no | no |
| KCNK3_HUMAN | [view interactions] | High throughput | no | no |
| 1433G_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| BARD1_HUMAN | [view interactions] | High throughput | no | yes |
| BRCA1_HUMAN | [view interactions] | High throughput | no | yes |
| DNLI4_HUMAN | [view interactions] | High throughput | no | yes |
| PAXI1_HUMAN | [view interactions] | High throughput | no | no |
| T22D2_HUMAN | [view interactions] | High throughput | no | yes |
| ELAV1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TERA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ITA4_HUMAN | [view interactions] | High throughput | no | no |
| UBC_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MBD5_HUMAN | [view interactions] | High throughput | no | no |
| ITPI2_HUMAN | [view interactions] | High throughput | no | yes |
| KCAB2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NR2C2_HUMAN | [view interactions] | High throughput | no | yes |
| UBQL2_HUMAN | [view interactions] | High throughput | no | yes |
| PTER_HUMAN | [view interactions] | High throughput | no | yes |
| KCNE3_HUMAN | [view interactions] | High throughput | no | yes |
| VP26B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SNX12_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RN149_HUMAN | [view interactions] | High throughput | no | no |
| STX17_HUMAN | [view interactions] | High throughput | no | yes |
| PPIL3_HUMAN | [view interactions] | High throughput | no | yes |
| CENPM_HUMAN | [view interactions] | High throughput | no | yes |
| UROL1_HUMAN | [view interactions] | High throughput | no | no |
| MARH1_HUMAN | [view interactions] | High throughput | no | yes |
| DDX55_HUMAN | [view interactions] | High throughput | no | yes |
| STA5B_HUMAN | [view interactions] | High throughput | no | yes |
| UBXN6_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ARL4D_HUMAN | [view interactions] | High throughput | no | no |
| UBP32_HUMAN | [view interactions] | High throughput | no | yes |
| DERL2_HUMAN | [view interactions] | High throughput | no | yes |
| CLASR_HUMAN | [view interactions] | High throughput | no | yes |
| FACC1_HUMAN | [view interactions] | High throughput | no | no |
| SIAH1_HUMAN | [view interactions] | High throughput | no | yes |
| RFXK_HUMAN | [view interactions] | High throughput | no | yes |
| CIA2A_HUMAN | [view interactions] | High throughput | no | yes |
| T183A_HUMAN | [view interactions] | High throughput | no | no |
| DHH_HUMAN | [view interactions] | High throughput | no | no |
| XPA_HUMAN | [view interactions] | High throughput | no | yes |
| RN166_HUMAN | [view interactions] | High throughput | no | no |
| IF4A3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GO45_HUMAN | [view interactions] | High throughput | no | yes |
| KLK15_HUMAN | [view interactions] | High throughput | no | no |
| WIF1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| NPAS1_HUMAN | [view interactions] | High throughput | no | no |
| EFMT3_HUMAN | [view interactions] | High throughput | no | no |
| SIR3_HUMAN | [view interactions] | High throughput | no | yes |
| NTNG1_HUMAN | [view interactions] | High throughput | no | no |
| RHOJ_HUMAN | [view interactions] | High throughput | no | yes |
| RHOQ_HUMAN | [view interactions] | High throughput | no | no |
| RHOU_HUMAN | [view interactions] | High throughput | no | no |
| RHOC_HUMAN | [view interactions] | High throughput | no | no |
| RPAC1_HUMAN | [view interactions] | High throughput | no | no |
| VPS29_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AURKA_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| FOXC1_HUMAN | [view interactions] | High throughput | no | no |
| ZRAN1_HUMAN | [view interactions] | High throughput | no | yes |
| PARPT_HUMAN | [view interactions] | High throughput | no | no |
| TRI67_HUMAN | [view interactions] | High throughput | no | no |
| NDUA7_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SBDS_HUMAN | [view interactions] | High throughput | no | yes |
| PPM1G_HUMAN | [view interactions] | High throughput | no | no |
| NDUA2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RM53_HUMAN | [view interactions] | High throughput | no | yes |
| SRPRB_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| SUGP1_HUMAN | [view interactions] | High throughput | no | yes |
| SSBP_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RBMS1_HUMAN | [view interactions] | High throughput | no | no |
| SC23A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PPIA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| IGBP1_HUMAN | [view interactions] | High throughput | no | yes |
| PSB1_HUMAN | [view interactions] | High throughput | no | yes |
| SAHH2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| STX7_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ZC11A_HUMAN | [view interactions] | High throughput | no | yes |
| PLST_HUMAN | [view interactions] | High throughput | no | yes |
| AK1A1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| AK1C2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| NDKB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PIN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RBM12_HUMAN | [view interactions] | High throughput | no | yes |
| CAPG_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CRIP1_HUMAN | [view interactions] | High throughput | no | yes |
| DAZP1_HUMAN | [view interactions] | High throughput | no | yes |
| DYL1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| GLOD4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AATC_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HEBP1_HUMAN | [view interactions] | High throughput | no | yes |
| HGS_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MTAP_HUMAN | [view interactions] | High throughput | no | no |
| PIR_HUMAN | [view interactions] | High throughput | no | no |
| P4R3A_HUMAN | [view interactions] | High throughput | no | yes |
| TRIP6_HUMAN | [view interactions] | High throughput | no | yes |
| UB2L3_HUMAN | [view interactions] | High throughput | no | yes |
| TAGL_HUMAN | [view interactions] | High throughput | no | no |
| TAGL2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| TAGL3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SNX2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| PIMT_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TKT_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ZC3H6_HUMAN | [view interactions] | High throughput | no | yes |
| PIPNA_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| SNX1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DCTN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TBCD5_HUMAN | [view interactions] | High throughput | no | yes |
| SNX6_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| SNX5_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| OPTN_HUMAN | [view interactions] | High throughput | no | yes |
| ANFY1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ARF6_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| B3GA1_HUMAN | [view interactions] | High throughput | no | yes |
| CAV1_HUMAN | [view interactions] | High throughput | no | no |
| LAMP2_HUMAN | [view interactions] | High throughput | no | yes |
| LAMP3_HUMAN | [view interactions] | High throughput | no | no |
| LTOR1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MARCS_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RAB2A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RAB4A_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RAB5A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RAB5C_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TFR1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| IFM1_HUMAN | [view interactions] | High throughput | no | no |
| DPP4_HUMAN | [view interactions] | High throughput | no | no |
| BASI_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| IFM3_HUMAN | [view interactions] | High throughput | no | yes |
| TM11B_HUMAN | [view interactions] | High throughput | no | no |
| ACE2_HUMAN | [view interactions] | High throughput | no | no |
| ATG9A_HUMAN | [view interactions] | High throughput | no | yes |
| ARF3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ARL14_HUMAN | [view interactions] | High throughput | no | no |
| ARL15_HUMAN | [view interactions] | High throughput | no | yes |
| PRKN_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FHI1A_HUMAN | [view interactions] | High throughput | no | yes |
| RB11A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RAB25_HUMAN | [view interactions] | High throughput | no | no |
| A16L1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MUC18_HUMAN | [view interactions] | High throughput | no | yes |
| ABL1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CRK_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| SRC_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| FYN_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| GRB2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NCK1_HUMAN | [view interactions] | High throughput | no | yes |
| CXB2_HUMAN | [view interactions] | High throughput | no | yes |
| TFG_HUMAN | [view interactions] | High throughput | no | yes |
| PYRG2_HUMAN | [view interactions] | High throughput | no | yes |
| ANO3_HUMAN | [view interactions] | High throughput | no | yes |
| RT05_HUMAN | [view interactions] | High throughput | no | yes |
| MPDZ_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PYRG1_HUMAN | [view interactions] | High throughput | no | no |
| SMC1A_HUMAN | [view interactions] | High throughput | no | yes |
| SNR27_HUMAN | [view interactions] | High throughput | no | yes |
| CAV3_HUMAN | [view interactions] | High throughput | no | no |
| MANS1_HUMAN | [view interactions] | High throughput | no | yes |
| SPB5_HUMAN | [view interactions] | High throughput | no | no |
| EAA3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MRAP2_HUMAN | [view interactions] | High throughput | no | no |
| FIBB_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| FCGRN_HUMAN | [view interactions] | High throughput | no | yes |
| AR6P6_HUMAN | [view interactions] | High throughput | no | yes |
| T2R41_HUMAN | [view interactions] | High throughput | no | no |
| UBP47_HUMAN | [view interactions] | High throughput | no | yes |
| H17B6_HUMAN | [view interactions] | High throughput | no | yes |
| CP1A1_HUMAN | [view interactions] | High throughput | no | yes |
| SPY2_HUMAN | [view interactions] | High throughput | no | yes |
| SCNM1_HUMAN | [view interactions] | High throughput | no | no |
| SETD3_HUMAN | [view interactions] | High throughput | no | yes |
| SIR4_HUMAN | [view interactions] | High throughput | no | yes |
| LRRK2_HUMAN | [view interactions] | High throughput | no | yes |
| VCAM1_HUMAN | [view interactions] | High throughput | no | no |
| HMGA2_HUMAN | [view interactions] | High throughput | no | yes |
| ATG5_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| VHL_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CRCM_HUMAN | [view interactions] | High throughput | no | no |
| IKKE_HUMAN | [view interactions] | High throughput | no | yes |
| HLAB_HUMAN | [view interactions] | High throughput | no | yes |
| EPB41_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| PTBP3_HUMAN | [view interactions] | High throughput | no | no |
| BMI1_HUMAN | [view interactions] | High throughput | no | yes |
| AR6P1_HUMAN | [view interactions] | High throughput | no | yes |
| RPRM_HUMAN | [view interactions] | High throughput | no | no |
| STX11_HUMAN | [view interactions] | High throughput | no | yes |
| TMM17_HUMAN | [view interactions] | High throughput | no | yes |
| BET1_HUMAN | [view interactions] | High throughput | no | no |
| LAMP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RAB9A_HUMAN | [view interactions] | High throughput | no | yes |
| TGON2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RASK_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RASN_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RASH_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| EGFR_HUMAN | [view interactions] | High throughput | no | no |
| FHI1B_HUMAN | [view interactions] | High throughput | no | yes |
| SWAP1_HUMAN | [view interactions] | High throughput | no | no |