Features Interactions Isoform Disease Linear motifs Fingerprint Network All partners

PIN1_HUMAN

Peptidyl-prolyl cis/trans isomerase (PPIase) that binds to and isomerizes specific phosphorylated Ser/Thr-Pro (pSer/Thr-Pro) motifs (PubMed, PubMed, PubMed). By inducing conformational changes in a subset of phosphorylated proteins, acts as a molecular switch in multiple cellular processes (PubMed, PubMed, PubMed). Displays a preference for acidic residues located N-terminally to the proline bond to be isomerized. Regulates mitosis presumably by interacting with NIMA and attenuating its mitosis-promoting activity. Down-regulates kinase activity of BTK (PubMed). Can transactivate multiple oncogenes and induce centrosome amplification, chromosome instability and cell transformation. Required for the efficient dephosphorylation and recycling of RAF1 after mitogen activation (PubMed). Binds and targets PML and BCL6 for degradation in a phosphorylation-dependent manner (PubMed). Acts as a regulator of JNK cascade by binding to phosphorylated FBXW7, disrupting FBXW7 dimerization and promoting FBXW7 autoubiquitination and degradation: degradation of FBXW7 leads to subsequent stabilization of JUN (PubMed). May facilitate the ubiquitination and proteasomal degradation of RBBP8/CtIP through CUL3/KLHL15 E3 ubiquitin-protein ligase complex, hence favors DNA double-strand repair through error-prone non-homologous end joining (NHEJ) over error-free, RBBP8-mediated homologous recombination (HR) (PubMed, PubMed). Upon IL33-induced lung inflammation, catalyzes cis-trans isomerization of phosphorylated IRAK3/IRAK-M, inducing IRAK3 stabilization, nuclear translocation and expression of pro-inflammatory genes in dendritic cells (PubMed). [View more on UniProt]

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No data found.

No annotated instance was found. To search for linear motifs, use the ELM prediction server.

Molecular function

Term Name % Distance from the top of the tree Annotated in PIN1_HUMAN
GO:0017076 purine nucleotide binding 30.1205 4 no
GO:0032555 purine ribonucleotide binding 30.1205 4 no
GO:0035639 purine ribonucleoside triphosphate binding 28.9157 4 no
GO:0030554 adenyl nucleotide binding 27.7108 5 no
GO:0032559 adenyl ribonucleotide binding 27.7108 5 no
GO:0005524 ATP binding 26.5060 5 no
GO:0003723 RNA binding 21.6867 4 no
GO:0019900 kinase binding 20.4819 4 yes
GO:0019901 protein kinase binding 18.0723 5 yes
GO:0045309 protein phosphorylated amino acid binding 6.0241 4 yes
GO:0048156 tau protein binding 4.8193 4 yes
GO:0050815 phosphoserine residue binding 3.6145 5 yes

Biological process

Term Name % Distance from top the of the tree Annotated in PIN1_HUMAN
GO:0048522 positive regulation of cellular process 69.8795 4 yes
GO:0080090 regulation of primary metabolic process 68.6747 4 yes
GO:0031323 regulation of cellular metabolic process 67.4699 4 yes
GO:0051171 regulation of nitrogen compound metabolic process 66.2651 4 yes
GO:0060255 regulation of macromolecule metabolic process 66.2651 4 yes
GO:0048523 negative regulation of cellular process 65.0602 4 yes
GO:0009892 negative regulation of metabolic process 50.6024 4 yes
GO:0010646 regulation of cell communication 50.6024 4 yes
GO:0051128 regulation of cellular component organization 50.6024 4 yes
GO:0010468 regulation of gene expression 49.3976 5 yes
GO:0009893 positive regulation of metabolic process 48.1928 4 yes
GO:0010605 negative regulation of macromolecule metabolic process 48.1928 5 yes
GO:0009889 regulation of biosynthetic process 46.9880 4 yes
GO:0009966 regulation of signal transduction 46.9880 4 yes
GO:0051172 negative regulation of nitrogen compound metabolic process 46.9880 5 yes
GO:0010556 regulation of macromolecule biosynthetic process 45.7831 5 yes
GO:0031326 regulation of cellular biosynthetic process 45.7831 5 yes
GO:0051246 regulation of protein metabolic process 45.7831 5 yes
GO:0031324 negative regulation of cellular metabolic process 44.5783 5 yes
GO:0031325 positive regulation of cellular metabolic process 44.5783 5 yes
GO:0010604 positive regulation of macromolecule metabolic process 43.3735 5 yes
GO:0019219 regulation of nucleobase-containing compound metabolic process 43.3735 5 yes
GO:0051173 positive regulation of nitrogen compound metabolic process 43.3735 5 yes
GO:0051252 regulation of RNA metabolic process 42.1687 5 yes
GO:0036211 protein modification process 37.3494 4 yes
GO:0043412 macromolecule modification 37.3494 4 yes
GO:0006355 regulation of DNA-templated transcription 36.1446 6 yes
GO:0031399 regulation of protein modification process 36.1446 6 yes
GO:1903506 regulation of nucleic acid-templated transcription 36.1446 7 yes
GO:2001141 regulation of RNA biosynthetic process 36.1446 6 yes
GO:1902531 regulation of intracellular signal transduction 34.9398 5 yes
GO:0019220 regulation of phosphate metabolic process 33.7349 6 yes
GO:0051174 regulation of phosphorus metabolic process 33.7349 5 yes
GO:0051049 regulation of transport 33.7349 4 no
GO:0051248 negative regulation of protein metabolic process 32.5301 6 yes
GO:0006796 phosphate-containing compound metabolic process 32.5301 4 no
GO:0010941 regulation of cell death 32.5301 4 no
GO:0008104 protein localization 32.5301 4 no
GO:0048584 positive regulation of response to stimulus 31.3253 4 yes
GO:0051247 positive regulation of protein metabolic process 31.3253 6 yes
GO:0043067 regulation of programmed cell death 31.3253 5 no
GO:0045595 regulation of cell differentiation 30.1205 4 no
GO:0042981 regulation of apoptotic process 30.1205 6 no
GO:0006996 organelle organization 30.1205 4 no
GO:0010647 positive regulation of cell communication 28.9157 5 yes
GO:0023056 positive regulation of signaling 28.9157 4 yes
GO:0042325 regulation of phosphorylation 28.9157 7 yes
GO:0060548 negative regulation of cell death 28.9157 5 no
GO:0009891 positive regulation of biosynthetic process 27.7108 5 yes
GO:0031328 positive regulation of cellular biosynthetic process 27.7108 6 yes
GO:0045935 positive regulation of nucleobase-containing compound metabolic process 27.7108 6 yes
GO:0048585 negative regulation of response to stimulus 27.7108 4 yes
GO:0051338 regulation of transferase activity 27.7108 4 yes
GO:0043069 negative regulation of programmed cell death 27.7108 6 no
GO:0001932 regulation of protein phosphorylation 26.5060 7 yes
GO:0009967 positive regulation of signal transduction 26.5060 5 yes
GO:0010648 negative regulation of cell communication 26.5060 5 yes
GO:0023057 negative regulation of signaling 26.5060 4 yes
GO:0043085 positive regulation of catalytic activity 26.5060 4 yes
GO:0043066 negative regulation of apoptotic process 26.5060 7 no
GO:0071702 organic substance transport 26.5060 4 no
GO:0009968 negative regulation of signal transduction 25.3012 5 yes
GO:0010557 positive regulation of macromolecule biosynthetic process 25.3012 6 yes
GO:0033043 regulation of organelle organization 25.3012 5 yes
GO:0051254 positive regulation of RNA metabolic process 25.3012 6 yes
GO:0060341 regulation of cellular localization 25.3012 4 yes
GO:0009894 regulation of catabolic process 24.0964 4 yes
GO:0031401 positive regulation of protein modification process 24.0964 7 yes
GO:0071705 nitrogen compound transport 24.0964 4 no
GO:0051130 positive regulation of cellular component organization 24.0964 5 no
GO:0080134 regulation of response to stress 24.0964 4 no
GO:0006357 regulation of transcription by RNA polymerase II 22.8916 7 yes
GO:0010562 positive regulation of phosphorus metabolic process 22.8916 6 yes
GO:0042327 positive regulation of phosphorylation 22.8916 8 yes
GO:0045937 positive regulation of phosphate metabolic process 22.8916 7 yes
GO:0051094 positive regulation of developmental process 22.8916 4 no
GO:0022607 cellular component assembly 22.8916 4 no
GO:0001934 positive regulation of protein phosphorylation 21.6867 8 yes
GO:0045893 positive regulation of DNA-templated transcription 21.6867 7 yes
GO:1902680 positive regulation of RNA biosynthetic process 21.6867 7 yes
GO:1903508 positive regulation of nucleic acid-templated transcription 21.6867 8 yes
GO:0043549 regulation of kinase activity 21.6867 5 no
GO:0009890 negative regulation of biosynthetic process 21.6867 5 no
GO:0010558 negative regulation of macromolecule biosynthetic process 21.6867 6 no
GO:0042127 regulation of cell population proliferation 21.6867 4 no
GO:0015031 protein transport 21.6867 4 no
GO:0016310 phosphorylation 21.6867 5 no
GO:0018193 peptidyl-amino acid modification 20.4819 5 yes
GO:0032880 regulation of protein localization 20.4819 5 yes
GO:0043408 regulation of MAPK cascade 20.4819 6 yes
GO:0051347 positive regulation of transferase activity 20.4819 5 yes
GO:0016070 RNA metabolic process 20.4819 5 no
GO:0031400 negative regulation of protein modification process 20.4819 7 no
GO:0090304 nucleic acid metabolic process 20.4819 4 no
GO:0031327 negative regulation of cellular biosynthetic process 20.4819 6 no
GO:0006468 protein phosphorylation 20.4819 5 no
GO:0071310 cellular response to organic substance 20.4819 4 no
GO:0051336 regulation of hydrolase activity 19.2771 4 yes
GO:0051726 regulation of cell cycle 16.8675 4 yes
GO:0045944 positive regulation of transcription by RNA polymerase II 15.6627 8 yes
GO:0034330 cell junction organization 14.4578 4 yes
GO:0009895 negative regulation of catabolic process 13.2530 5 yes
GO:0034248 regulation of cellular amide metabolic process 13.2530 5 yes
GO:0051345 positive regulation of hydrolase activity 13.2530 5 yes
GO:0010564 regulation of cell cycle process 12.0482 5 yes
GO:0030111 regulation of Wnt signaling pathway 12.0482 5 yes
GO:1902532 negative regulation of intracellular signal transduction 12.0482 6 yes
GO:0042176 regulation of protein catabolic process 10.8434 5 yes
GO:2000145 regulation of cell motility 10.8434 4 yes
GO:0007346 regulation of mitotic cell cycle 9.6386 5 yes
GO:0043393 regulation of protein binding 9.6386 4 yes
GO:0050808 synapse organization 9.6386 5 yes
GO:0070372 regulation of ERK1 and ERK2 cascade 9.6386 7 yes
GO:0035303 regulation of dephosphorylation 8.4337 7 yes
GO:0035304 regulation of protein dephosphorylation 8.4337 7 yes
GO:0042177 negative regulation of protein catabolic process 7.2289 6 yes
GO:0051099 positive regulation of binding 7.2289 4 yes
GO:0032091 negative regulation of protein binding 6.0241 5 yes
GO:0032092 positive regulation of protein binding 6.0241 5 yes
GO:0043087 regulation of GTPase activity 6.0241 5 yes
GO:0043547 positive regulation of GTPase activity 6.0241 6 yes
GO:0051100 negative regulation of binding 6.0241 4 yes
GO:0060828 regulation of canonical Wnt signaling pathway 6.0241 6 yes
GO:1903320 regulation of protein modification by small protein conjugation or removal 6.0241 7 yes
GO:0030182 neuron differentiation 4.8193 4 yes
GO:0034249 negative regulation of cellular amide metabolic process 4.8193 6 yes
GO:0043409 negative regulation of MAPK cascade 4.8193 7 yes
GO:0050821 protein stabilization 4.8193 4 yes
GO:1900180 regulation of protein localization to nucleus 4.8193 6 yes
GO:0000413 protein peptidyl-prolyl isomerization 3.6145 7 yes
GO:0018208 peptidyl-proline modification 3.6145 6 yes
GO:0030177 positive regulation of Wnt signaling pathway 3.6145 6 yes
GO:0031396 regulation of protein ubiquitination 3.6145 8 yes
GO:0035306 positive regulation of dephosphorylation 3.6145 8 yes
GO:0035307 positive regulation of protein dephosphorylation 3.6145 8 yes
GO:0036293 response to decreased oxygen levels 3.6145 4 yes
GO:0040013 negative regulation of locomotion 3.6145 4 yes
GO:0051302 regulation of cell division 3.6145 4 yes
GO:1902991 regulation of amyloid precursor protein catabolic process 3.6145 6 yes
GO:0007088 regulation of mitotic nuclear division 2.4096 6 yes
GO:0031398 positive regulation of protein ubiquitination 2.4096 9 yes
GO:0032465 regulation of cytokinesis 2.4096 5 yes
GO:0051783 regulation of nuclear division 2.4096 6 yes
GO:0090263 positive regulation of canonical Wnt signaling pathway 2.4096 7 yes
GO:0090287 regulation of cellular response to growth factor stimulus 2.4096 4 yes
GO:1902003 regulation of amyloid-beta formation 2.4096 6 yes
GO:1903322 positive regulation of protein modification by small protein conjugation or removal 2.4096 8 yes
GO:2000146 negative regulation of cell motility 2.4096 5 yes

Disease

Term Name % Distance from top the of the tree Annotated in PIN1_HUMAN
DOID:0050686 organ system cancer 2.4096 3 no
Uniprot ID Details Highest evidence Localizing into PSD HPA (protein expression in neurons)
FOS_HUMAN [view interactions] Low throughput no yes
1433S_HUMAN [view entry] [view interactions] Low throughput yes yes
GLI1_HUMAN [view interactions] Low throughput no no
NCOA3_HUMAN [view interactions] Low throughput no yes
DAB2_HUMAN [view interactions] Low throughput no yes
CSK22_HUMAN [view entry] [view interactions] Low throughput yes no
WEE1_HUMAN [view interactions] Low throughput no yes
PLK1_HUMAN [view interactions] Low throughput no yes
CDC27_HUMAN [view interactions] Low throughput no yes
PMYT1_HUMAN [view interactions] Low throughput no no
MPIP3_HUMAN [view interactions] Low throughput no yes
JUN_HUMAN [view interactions] Low throughput no yes
BCL2_HUMAN [view interactions] Low throughput no no
RAB4A_HUMAN [view entry] [view interactions] Low throughput yes no
KI20B_HUMAN [view entry] [view interactions] Low throughput yes yes
RPB1_HUMAN [view interactions] Low throughput no no
MYT1_HUMAN [view interactions] Low throughput no yes
SMAD2_HUMAN [view interactions] Low throughput no yes
FOXO4_HUMAN [view interactions] Low throughput no no
MCL1_HUMAN [view interactions] Low throughput no yes
CDN1B_HUMAN [view interactions] Low throughput no yes
CTNB1_HUMAN [view entry] [view interactions] Low throughput yes yes
EGR1_HUMAN [view interactions] Low throughput no yes
PITX1_HUMAN [view interactions] Low throughput no yes
PIM1_HUMAN [view interactions] Low throughput no yes
FBXW7_HUMAN [view interactions] Low throughput no yes
RUNX3_HUMAN [view interactions] Low throughput no no
BCL6_HUMAN [view interactions] Low throughput no no
DAXX_HUMAN [view interactions] Low throughput no yes
TF65_HUMAN [view entry] [view interactions] Low throughput yes yes
IKBA_HUMAN [view interactions] Low throughput no yes
AATF_HUMAN [view interactions] Low throughput no yes
ERBB2_HUMAN [view entry] [view interactions] Low throughput yes no
IRF3_HUMAN [view interactions] Low throughput no yes
P73_HUMAN [view interactions] Low throughput no no
SYUA_HUMAN [view entry] [view interactions] Low throughput yes no
TAU_HUMAN [view entry] [view interactions] Low throughput yes yes
SNCAP_HUMAN [view interactions] Low throughput no no
MYB_HUMAN [view interactions] Low throughput no yes
SP1_HUMAN [view interactions] Low throughput no yes
PPARG_HUMAN [view interactions] Low throughput no yes
SGK1_HUMAN [view interactions] Low throughput no yes
REST_HUMAN [view interactions] Low throughput no yes
ATCAY_HUMAN [view interactions] Low throughput no no
FADD_HUMAN [view interactions] Low throughput no yes
SPT5H_HUMAN [view interactions] Low throughput no yes
FAP20_HUMAN [view interactions] Low throughput no no
GSK3A_HUMAN [view interactions] Low throughput no yes
TRI59_HUMAN [view interactions] Low throughput no no
KPYM_HUMAN [view interactions] Low throughput no yes
P53_HUMAN [view interactions] Low throughput no no
STK3_HUMAN [view interactions] Low throughput no yes
HIF1A_HUMAN [view interactions] Low throughput no no
ST4A1_HUMAN [view interactions] Low throughput no yes
TLE1_HUMAN [view interactions] Low throughput no yes
M3K8_HUMAN [view interactions] Low throughput no yes
HIPK2_HUMAN [view interactions] Low throughput no yes
MP2K1_HUMAN [view entry] [view interactions] Low throughput yes yes
HES1_HUMAN [view interactions] Low throughput no no
CCNE1_HUMAN [view interactions] Low throughput no no
NEK6_HUMAN [view interactions] Low throughput no yes
GEPH_HUMAN [view entry] [view interactions] Low throughput yes yes
NFAC2_HUMAN [view interactions] Low throughput no yes
RARA_HUMAN [view interactions] Low throughput no no
PML_HUMAN [view interactions] Low throughput no yes
RED1_HUMAN [view interactions] Low throughput no no
CDK10_HUMAN [view interactions] Low throughput no no
FOXC2_HUMAN [view interactions] Low throughput no no
RUNX2_HUMAN [view interactions] Low throughput no no
HOME1_HUMAN [view entry] [view interactions] Low throughput yes yes
SP140_HUMAN [view interactions] Low throughput no no
MP2K2_HUMAN [view entry] [view interactions] Low throughput yes yes
RAF1_HUMAN [view entry] [view interactions] Low throughput yes no
NANOG_HUMAN [view interactions] Low throughput no no
NANP8_HUMAN [view interactions] Low throughput no no
MYC_HUMAN [view interactions] Low throughput no yes
BARD1_HUMAN [view interactions] Low throughput no yes
NOTC1_HUMAN [view interactions] Low throughput no yes
TOP2A_HUMAN [view interactions] Low throughput no no
CSK21_HUMAN [view entry] [view interactions] Low throughput yes yes
A4_HUMAN [view entry] [view interactions] Low throughput yes yes
P63_HUMAN [view interactions] Low throughput no no
IRAK1_HUMAN [view interactions] Low throughput no yes
GRM5_HUMAN [view entry] [view interactions] Low throughput yes no
BRCA1_HUMAN [view interactions] Low throughput no yes
HDAC3_HUMAN [view interactions] Low throughput no yes
NCOR2_HUMAN [view interactions] Low throughput no yes
CDK2_HUMAN [view interactions] Low throughput no yes
EP300_HUMAN [view interactions] Low throughput no yes
SMAD3_HUMAN [view interactions] Low throughput no yes
CPEB1_HUMAN [view entry] [view interactions] Low throughput yes no
NHRF1_HUMAN [view interactions] Low throughput no no
SEPT9_HUMAN [view interactions] Low throughput no no
KCND2_HUMAN [view entry] [view interactions] Low throughput yes yes
KRT34_HUMAN [view interactions] High throughput no no
PKHG2_HUMAN [view interactions] High throughput no no
NUP35_HUMAN [view interactions] High throughput no yes
ZBTB2_HUMAN [view interactions] High throughput no yes
RB8NL_HUMAN [view interactions] High throughput no no
TRI27_HUMAN [view interactions] High throughput no yes
GMEB2_HUMAN [view interactions] High throughput no yes
NR4A3_HUMAN [view interactions] High throughput no yes
PBX1_HUMAN [view interactions] High throughput no yes
IN80E_HUMAN [view interactions] High throughput no yes
CC88B_HUMAN [view interactions] High throughput no no
ETV6_HUMAN [view interactions] High throughput no no
ZN526_HUMAN [view interactions] High throughput no yes
UBQL2_HUMAN [view interactions] High throughput no yes
ZN768_HUMAN [view interactions] High throughput no yes
KRT37_HUMAN [view interactions] High throughput no no
KR108_HUMAN [view interactions] High throughput no no
AF17_HUMAN [view interactions] High throughput no yes
KRA59_HUMAN [view interactions] High throughput no no
CCDC6_HUMAN [view interactions] High throughput no yes
MEOX1_HUMAN [view interactions] High throughput no no
MYF5_HUMAN [view interactions] High throughput no no
SELV_HUMAN [view interactions] High throughput no no
PDLI7_HUMAN [view entry] [view interactions] High throughput yes no
FOSL1_HUMAN [view interactions] High throughput no yes
UBX2B_HUMAN [view interactions] High throughput no no
FUCO2_HUMAN [view interactions] High throughput no no
ZN449_HUMAN [view interactions] High throughput no no
ARI5A_HUMAN [view interactions] High throughput no yes
SCAI_HUMAN [view entry] [view interactions] High throughput yes yes
HXA1_HUMAN [view interactions] High throughput no no
ZBT42_HUMAN [view interactions] High throughput no yes
AJUBA_HUMAN [view interactions] High throughput no yes
PLAL2_HUMAN [view interactions] High throughput no no
TFPT_HUMAN [view interactions] High throughput no yes
NGAL_HUMAN [view interactions] High throughput no no
FHL5_HUMAN [view interactions] High throughput no no
NDF4_HUMAN [view interactions] High throughput no no
NELFA_HUMAN [view interactions] High throughput no yes
RN208_HUMAN [view interactions] High throughput no no
CC036_HUMAN [view interactions] High throughput no no
GP152_HUMAN [view interactions] High throughput no no
ZN446_HUMAN [view interactions] High throughput no yes
SOCS3_HUMAN [view interactions] High throughput no yes
DDX24_HUMAN [view interactions] High throughput no yes
LEPR_HUMAN [view interactions] High throughput no no
KLH20_HUMAN [view interactions] High throughput no yes
GPAA1_HUMAN [view interactions] High throughput no yes
PTOV1_HUMAN [view interactions] High throughput no yes
ZCH10_HUMAN [view interactions] High throughput no yes
CHSS2_HUMAN [view interactions] High throughput no yes
MTFR1_HUMAN [view interactions] High throughput no yes
GGA2_HUMAN [view interactions] High throughput no yes
HNRPC_HUMAN [view interactions] High throughput no yes
CTIP_HUMAN [view interactions] High throughput no no
CEP19_HUMAN [view interactions] High throughput no no
BAG6_HUMAN [view entry] [view interactions] High throughput yes yes
ARHGF_HUMAN [view entry] [view interactions] High throughput yes no
ATL4_HUMAN [view interactions] High throughput no yes
HOMEZ_HUMAN [view interactions] High throughput no no
CCD33_HUMAN [view interactions] High throughput no no
AMOT_HUMAN [view interactions] High throughput no no
KR101_HUMAN [view interactions] High throughput no no
KR103_HUMAN [view interactions] High throughput no no
EYA2_HUMAN [view interactions] High throughput no yes
EFS_HUMAN [view interactions] High throughput no no
TOX3_HUMAN [view interactions] High throughput no yes
ATN1_HUMAN [view interactions] High throughput no yes
BRD8_HUMAN [view interactions] High throughput no yes
BC11A_HUMAN [view entry] [view interactions] High throughput yes yes
MTG16_HUMAN [view interactions] High throughput no yes
HTF4_HUMAN [view interactions] High throughput no yes
KIFC3_HUMAN [view interactions] High throughput no no
SCYL1_HUMAN [view interactions] High throughput no yes
FRS2_HUMAN [view interactions] High throughput no no
FOXI1_HUMAN [view interactions] High throughput no no
ZN783_HUMAN [view interactions] High throughput no no
SPN90_HUMAN [view entry] [view interactions] High throughput yes no
KCTD7_HUMAN [view interactions] High throughput no no
CC153_HUMAN [view interactions] High throughput no no
GRSF1_HUMAN [view interactions] High throughput no yes
ITA4_HUMAN [view interactions] High throughput no no
CUL7_HUMAN [view interactions] High throughput no yes
SSBP2_HUMAN [view interactions] High throughput no yes
SSBP4_HUMAN [view interactions] High throughput no no
M3K11_HUMAN [view interactions] High throughput no yes
DUS6_HUMAN [view interactions] High throughput no yes
MOCS1_HUMAN [view interactions] High throughput no yes
IPKB_HUMAN [view interactions] High throughput no yes
UHRF2_HUMAN [view interactions] High throughput no no
TNIP1_HUMAN [view interactions] High throughput no yes
NUP98_HUMAN [view interactions] High throughput no no
SHKB1_HUMAN [view interactions] High throughput no yes
TNIP2_HUMAN [view interactions] High throughput no yes
APLP1_HUMAN [view interactions] High throughput no yes
A16L1_HUMAN [view entry] [view interactions] High throughput yes yes
ATPB_HUMAN [view interactions] High throughput no yes
BACH1_HUMAN [view interactions] High throughput no no
CREL2_HUMAN [view interactions] High throughput no yes
LRIF1_HUMAN [view interactions] High throughput no yes
CHSP1_HUMAN [view interactions] High throughput no yes
TIF1B_HUMAN [view interactions] High throughput no yes
CASP6_HUMAN [view interactions] High throughput no no
LRRK2_HUMAN [view interactions] High throughput no yes
CC90B_HUMAN [view interactions] High throughput no yes
CENPB_HUMAN [view interactions] High throughput no yes
HNRH1_HUMAN [view entry] [view interactions] High throughput yes yes
COBA2_HUMAN [view interactions] High throughput no no
INS_HUMAN [view interactions] High throughput no no
CPNE6_HUMAN [view entry] [view interactions] High throughput yes yes
BRD4_HUMAN [view interactions] High throughput no yes
CSAD_HUMAN [view interactions] High throughput no yes
TRI67_HUMAN [view interactions] High throughput no no
DDAH2_HUMAN [view interactions] High throughput no yes
DIDO1_HUMAN [view interactions] High throughput no yes
DEAF1_HUMAN [view interactions] High throughput no yes
VPS16_HUMAN [view entry] [view interactions] High throughput yes yes
DMPK_HUMAN [view interactions] High throughput no yes
RPB4_HUMAN [view interactions] High throughput no yes
DC1I1_HUMAN [view entry] [view interactions] High throughput yes yes
SPT6H_HUMAN [view interactions] High throughput no yes
EIF3G_HUMAN [view interactions] High throughput no yes
KTU_HUMAN [view interactions] High throughput no yes
KIF5A_HUMAN [view entry] [view interactions] High throughput yes yes
ASHWN_HUMAN [view interactions] High throughput no yes
KMT2B_HUMAN [view interactions] High throughput no no
T2EB_HUMAN [view interactions] High throughput no yes
RL35A_HUMAN [view entry] [view interactions] High throughput yes no
SYQ_HUMAN [view interactions] High throughput no yes
RPR1B_HUMAN [view interactions] High throughput no yes
APBA1_HUMAN [view interactions] High throughput no no
TRM2A_HUMAN [view interactions] High throughput no yes
ZN684_HUMAN [view interactions] High throughput no no
TSC2_HUMAN [view entry] [view interactions] High throughput yes yes
OSGEP_HUMAN [view interactions] High throughput no yes
U119A_HUMAN [view interactions] High throughput no no
WIZ_HUMAN [view interactions] High throughput no yes
ANDR_HUMAN [view interactions] High throughput no no
RASK_HUMAN [view entry] [view interactions] High throughput yes no
AXIN1_HUMAN [view interactions] High throughput no yes
SLX4_HUMAN [view interactions] High throughput no yes
BCLF1_HUMAN [view interactions] High throughput no yes
CDK12_HUMAN [view interactions] High throughput no yes
MED1_HUMAN [view interactions] High throughput no no
TR150_HUMAN [view interactions] High throughput no yes
TLE3_HUMAN [view interactions] High throughput no yes
DDX17_HUMAN [view entry] [view interactions] High throughput yes yes
DDX3X_HUMAN [view entry] [view interactions] High throughput yes yes
DDX5_HUMAN [view entry] [view interactions] High throughput yes yes
DHX15_HUMAN [view interactions] High throughput no yes
VIR_HUMAN [view interactions] High throughput no yes
OTUB1_HUMAN [view interactions] High throughput no yes
STPAP_HUMAN [view interactions] High throughput no no
KSR1_HUMAN [view interactions] High throughput no yes
G3BP2_HUMAN [view entry] [view interactions] High throughput yes yes
SNR27_HUMAN [view interactions] High throughput no yes
G3BP1_HUMAN [view interactions] High throughput no yes
PI42A_HUMAN [view entry] [view interactions] High throughput yes yes
HNRPK_HUMAN [view entry] [view interactions] High throughput yes yes
CP1A1_HUMAN [view interactions] High throughput no yes
HNRPU_HUMAN [view interactions] High throughput no yes
SYAP1_HUMAN [view entry] [view interactions] High throughput yes yes
U5S1_HUMAN [view interactions] High throughput no yes
PABP1_HUMAN [view entry] [view interactions] High throughput yes yes
PRP8_HUMAN [view interactions] High throughput no yes
RNPS1_HUMAN [view interactions] High throughput no yes
SFPQ_HUMAN [view entry] [view interactions] High throughput yes yes
SRS11_HUMAN [view interactions] High throughput no yes
SRRM1_HUMAN [view interactions] High throughput no yes
SRRM2_HUMAN [view interactions] High throughput no yes
VCAM1_HUMAN [view interactions] High throughput no no
U2AF2_HUMAN [view interactions] High throughput no yes
U520_HUMAN [view interactions] High throughput no yes
RL4_HUMAN [view entry] [view interactions] High throughput yes yes
DDB1_HUMAN [view interactions] High throughput no yes
WRIP1_HUMAN [view interactions] High throughput no yes
CD11B_HUMAN [view interactions] High throughput no yes
PAK2_HUMAN [view entry] [view interactions] High throughput yes no
CD11A_HUMAN [view interactions] High throughput no yes
HLAC_HUMAN [view interactions] High throughput no no
XRCC6_HUMAN [view interactions] High throughput no yes
EIF1B_HUMAN [view interactions] High throughput no no
MAP1S_HUMAN [view interactions] High throughput no no
VHL_HUMAN [view entry] [view interactions] High throughput yes yes
AP2A1_HUMAN [view entry] [view interactions] High throughput yes yes
TRM7_HUMAN [view interactions] High throughput no yes
REPS1_HUMAN [view interactions] High throughput no yes
TRAF6_HUMAN [view interactions] High throughput no yes
CHAP1_HUMAN [view interactions] High throughput no yes
AAKB1_HUMAN [view interactions] High throughput no yes
CAPR1_HUMAN [view entry] [view interactions] High throughput yes yes
EPB41_HUMAN [view entry] [view interactions] High throughput yes no
TBCD4_HUMAN [view interactions] High throughput no yes
TFG_HUMAN [view interactions] High throughput no yes
ECHA_HUMAN [view entry] [view interactions] High throughput yes yes
CCNK_HUMAN [view interactions] High throughput no yes
UBQL4_HUMAN [view interactions] High throughput no yes
MEOX2_HUMAN [view interactions] High throughput no no
CEP55_HUMAN [view interactions] High throughput no yes
ZBT7B_HUMAN [view interactions] High throughput no no
NDUA7_HUMAN [view entry] [view interactions] High throughput yes yes
ZBT22_HUMAN [view interactions] High throughput no no
UBE2A_HUMAN [view interactions] High throughput no no
FOXP2_HUMAN [view interactions] High throughput no yes
PP2AA_HUMAN [view entry] [view interactions] High throughput yes yes
ZBT14_HUMAN [view interactions] High throughput no yes
YAP1_HUMAN [view interactions] High throughput no yes
DAB1_HUMAN [view interactions] High throughput no yes
VATB2_HUMAN [view entry] [view interactions] High throughput yes yes
KRT38_HUMAN [view interactions] High throughput no no
FKB1A_HUMAN [view interactions] High throughput no yes
ITF2_HUMAN [view interactions] High throughput no yes
FKB1B_HUMAN [view entry] [view interactions] High throughput yes yes
CBS_HUMAN [view interactions] High throughput no yes
HINT1_HUMAN [view interactions] High throughput no yes
NUP62_HUMAN [view interactions] High throughput no yes
MSI2H_HUMAN [view interactions] High throughput no yes
KR107_HUMAN [view interactions] High throughput no no
NDKB_HUMAN [view entry] [view interactions] High throughput yes yes
KR109_HUMAN [view interactions] High throughput no no
PCBP2_HUMAN [view entry] [view interactions] High throughput yes yes
GOGA2_HUMAN [view entry] [view interactions] High throughput yes yes
COF1_HUMAN [view entry] [view interactions] High throughput yes no
TRAF2_HUMAN [view interactions] High throughput no yes
DAZP1_HUMAN [view interactions] High throughput no yes
TRAF1_HUMAN [view interactions] High throughput no no
FABP5_HUMAN [view entry] [view interactions] High throughput yes no
IKZF1_HUMAN [view interactions] High throughput no no
GPX4_HUMAN [view entry] [view interactions] High throughput yes no
NONO_HUMAN [view interactions] High throughput no yes
HDAC1_HUMAN [view interactions] High throughput no no
K1H1_HUMAN [view interactions] High throughput no no
CH10_HUMAN [view interactions] High throughput no yes
TRIP6_HUMAN [view interactions] High throughput no yes
SNX12_HUMAN [view entry] [view interactions] High throughput yes yes
NAB2_HUMAN [view interactions] High throughput no yes
SNX3_HUMAN [view entry] [view interactions] High throughput yes no
CC184_HUMAN [view interactions] High throughput no no
SPRE_HUMAN [view interactions] High throughput no yes
MTUS2_HUMAN [view interactions] High throughput no yes
TAGL2_HUMAN [view entry] [view interactions] High throughput yes no
K1C40_HUMAN [view interactions] High throughput no no
TAGL3_HUMAN [view entry] [view interactions] High throughput yes yes
ANR40_HUMAN [view interactions] High throughput no yes
PPIA_HUMAN [view entry] [view interactions] High throughput yes yes
RAI1_HUMAN [view interactions] High throughput no yes
SODC_HUMAN [view interactions] High throughput no yes
TAB3_HUMAN [view interactions] High throughput no yes
TBCA_HUMAN [view interactions] High throughput no yes
CBY2_HUMAN [view interactions] High throughput no no
ZO1_HUMAN [view entry] [view interactions] High throughput yes no
PNMA1_HUMAN [view interactions] High throughput no yes
PP2AB_HUMAN [view interactions] High throughput no yes
ZMIZ2_HUMAN [view interactions] High throughput no yes
2AAA_HUMAN [view entry] [view interactions] High throughput yes no
CEP76_HUMAN [view interactions] High throughput no yes
2ABA_HUMAN [view interactions] High throughput no yes
RBPMS_HUMAN [view interactions] High throughput no no
BICD1_HUMAN [view interactions] High throughput no yes
CNKR1_HUMAN [view interactions] High throughput no no
BICD2_HUMAN [view interactions] High throughput no yes
JKIP2_HUMAN [view entry] [view interactions] High throughput yes no
CLPP_HUMAN [view interactions] High throughput no yes
ZBTB9_HUMAN [view interactions] High throughput no no
PRRC1_HUMAN [view interactions] High throughput no yes
HEXI2_HUMAN [view interactions] High throughput no yes
MDFI_HUMAN [view interactions] High throughput no no
THAP7_HUMAN [view interactions] High throughput no no
SSBP3_HUMAN [view interactions] High throughput no no
KRA42_HUMAN [view interactions] High throughput no no
ABI2_HUMAN [view entry] [view interactions] High throughput yes yes
IKZF3_HUMAN [view interactions] High throughput no no
T22D4_HUMAN [view entry] [view interactions] High throughput yes no
KR106_HUMAN [view interactions] High throughput no no
PAX6_HUMAN [view interactions] High throughput no no
TNS2_HUMAN [view interactions] High throughput no no
SRCRL_HUMAN [view interactions] High throughput no yes
E2F4_HUMAN [view interactions] High throughput no no
FOXN1_HUMAN [view interactions] High throughput no no
GG6L9_HUMAN [view interactions] High throughput no no
GSK3B_HUMAN [view entry] [view interactions] Computational yes yes
1433Z_HUMAN [view entry] [view interactions] Computational yes yes
NCF2_HUMAN [view interactions] Computational no no
KPCA_HUMAN [view entry] [view interactions] Computational yes yes
UBXN7_HUMAN [view interactions] Computational no yes
CCNB1_HUMAN [view interactions] Computational no no
MK03_HUMAN [view entry] [view interactions] Computational yes yes
1433E_HUMAN [view entry] [view interactions] Computational yes yes
MAX_HUMAN [view interactions] Computational no yes
1433G_HUMAN [view entry] [view interactions] Computational yes yes
NCF4_HUMAN [view interactions] Computational no no
KPCZ_HUMAN [view entry] [view interactions] Computational yes yes
2A5A_HUMAN [view interactions] Computational no yes
1433T_HUMAN [view entry] [view interactions] Computational yes yes
CDK1_HUMAN [view interactions] Computational no no
NCF1_HUMAN [view interactions] Computational no no
MK01_HUMAN [view entry] [view interactions] Computational yes yes
KPCD_HUMAN [view entry] [view interactions] Computational yes yes
1433B_HUMAN [view entry] [view interactions] Computational yes yes
1433F_HUMAN [view entry] [view interactions] Computational yes yes