NDUA7_HUMAN
Evidence for PS localization
Functions
Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. [View more on UniProt]
Protein features
Binary interactions with known binding regions
To display all evidence describing the interaction with a partner, click on the protein name left to the bars.
Network
Isoforms
Disease-causing germline mutations
No data found.
Linear motifs
No annotated instance was found. To search for linear motifs, use the ELM prediction server.
Fingerprint
Molecular function
| Term | Name | % | Distance from the top of the tree | Annotated in NDUA7_HUMAN |
|---|---|---|---|---|
| GO:0015399 | primary active transmembrane transporter activity | 37.9747 | 4 | yes |
| GO:0015453 | oxidoreduction-driven active transmembrane transporter activity | 37.9747 | 5 | yes |
| GO:0003954 | NADH dehydrogenase activity | 29.1139 | 4 | yes |
| GO:0003955 | NAD(P)H dehydrogenase (quinone) activity | 29.1139 | 5 | yes |
| GO:0008137 | NADH dehydrogenase (ubiquinone) activity | 29.1139 | 4 | yes |
| GO:0016655 | oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor | 29.1139 | 4 | yes |
| GO:0050136 | NADH dehydrogenase (quinone) activity | 29.1139 | 5 | yes |
| GO:0046872 | metal ion binding | 25.3165 | 4 | no |
| GO:0003723 | RNA binding | 20.2532 | 4 | no |
Biological process
| Term | Name | % | Distance from top the of the tree | Annotated in NDUA7_HUMAN |
|---|---|---|---|---|
| GO:0022607 | cellular component assembly | 45.5696 | 4 | no |
| GO:0009060 | aerobic respiration | 41.7722 | 6 | yes |
| GO:0015980 | energy derivation by oxidation of organic compounds | 41.7722 | 4 | yes |
| GO:0045333 | cellular respiration | 41.7722 | 5 | yes |
| GO:0022900 | electron transport chain | 39.2405 | 4 | yes |
| GO:0022904 | respiratory electron transport chain | 39.2405 | 5 | yes |
| GO:0019646 | aerobic electron transport chain | 37.9747 | 6 | yes |
| GO:0043933 | protein-containing complex organization | 35.4430 | 4 | no |
| GO:0065003 | protein-containing complex assembly | 34.1772 | 5 | no |
| GO:0006120 | mitochondrial electron transport, NADH to ubiquinone | 27.8481 | 7 | yes |
| GO:0006996 | organelle organization | 27.8481 | 4 | no |
| GO:0033108 | mitochondrial respiratory chain complex assembly | 25.3165 | 6 | no |
| GO:0048522 | positive regulation of cellular process | 24.0506 | 4 | no |
| GO:0010257 | NADH dehydrogenase complex assembly | 22.7848 | 6 | no |
| GO:0032981 | mitochondrial respiratory chain complex I assembly | 22.7848 | 7 | no |
| GO:0060255 | regulation of macromolecule metabolic process | 22.7848 | 4 | no |
| GO:0008104 | protein localization | 21.5190 | 4 | no |
| GO:0080090 | regulation of primary metabolic process | 21.5190 | 4 | no |
| GO:0031323 | regulation of cellular metabolic process | 20.2532 | 4 | no |
| GO:0048523 | negative regulation of cellular process | 20.2532 | 4 | no |
| GO:0051171 | regulation of nitrogen compound metabolic process | 20.2532 | 4 | no |
| GO:0044271 | cellular nitrogen compound biosynthetic process | 8.8608 | 4 | yes |
| GO:0009059 | macromolecule biosynthetic process | 7.5949 | 4 | yes |
| GO:0043603 | cellular amide metabolic process | 7.5949 | 4 | yes |
| GO:0043604 | amide biosynthetic process | 7.5949 | 5 | yes |
| GO:1901566 | organonitrogen compound biosynthetic process | 7.5949 | 4 | yes |
| GO:0034645 | cellular macromolecule biosynthetic process | 6.3291 | 4 | yes |
| GO:0006412 | translation | 5.0633 | 4 | yes |
| GO:0006518 | peptide metabolic process | 5.0633 | 4 | yes |
| GO:0043043 | peptide biosynthetic process | 5.0633 | 5 | yes |
Disease
| Term | Name | % | Distance from top the of the tree | Annotated in NDUA7_HUMAN |
|---|---|---|---|---|
| DOID:700 | mitochondrial metabolism disease | 2.5316 | 3 | no |
All partners
| Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
|---|---|---|---|---|
| NDUAC_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| NDUS3_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| NDUS4_HUMAN | [view interactions] | Low throughput | no | yes |
| NDUA9_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| NDUS6_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| NDUS7_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| NDUAD_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| NDUA5_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| NDUA6_HUMAN | [view interactions] | Low throughput | no | no |
| NDUA2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| ACPM_HUMAN | [view interactions] | Low throughput | no | yes |
| NDUS1_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| NDUV3_HUMAN | [view interactions] | Low throughput | no | yes |
| NDUS8_HUMAN | [view interactions] | Low throughput | no | yes |
| NDUS2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| NDUV1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| NDUV2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| NDUS5_HUMAN | [view interactions] | High throughput | no | yes |
| BMR1A_HUMAN | [view interactions] | High throughput | no | no |
| RAB5C_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RMD3_HUMAN | [view interactions] | High throughput | no | yes |
| RAB7A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TMED2_HUMAN | [view interactions] | High throughput | no | yes |
| VAPA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| EMC5_HUMAN | [view interactions] | High throughput | no | yes |
| GOT1B_HUMAN | [view interactions] | High throughput | no | yes |
| VAPB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NDUA8_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FUT1_HUMAN | [view interactions] | High throughput | no | no |
| ENPP6_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| DJC30_HUMAN | [view interactions] | High throughput | no | no |
| SSMM1_HUMAN | [view interactions] | High throughput | no | no |
| NMES1_HUMAN | [view interactions] | High throughput | no | no |
| NDUA4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CX6B1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CAPZB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HSC20_HUMAN | [view interactions] | High throughput | no | yes |
| MDFI_HUMAN | [view interactions] | High throughput | no | no |
| RBTN1_HUMAN | [view interactions] | High throughput | no | no |
| TTPA_HUMAN | [view interactions] | High throughput | no | no |
| RTP2_HUMAN | [view interactions] | High throughput | no | no |
| AAKB1_HUMAN | [view interactions] | High throughput | no | yes |
| RNZ2_HUMAN | [view interactions] | High throughput | no | yes |
| STAR9_HUMAN | [view interactions] | High throughput | no | yes |
| ESR1_HUMAN | [view interactions] | High throughput | no | no |
| AKIP_HUMAN | [view interactions] | High throughput | no | yes |
| CH60_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| COX14_HUMAN | [view interactions] | High throughput | no | yes |
| MGST3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PDK1_HUMAN | [view interactions] | High throughput | no | yes |
| SCO1_HUMAN | [view interactions] | High throughput | no | yes |
| TR61B_HUMAN | [view interactions] | High throughput | no | yes |
| FHI2B_HUMAN | [view interactions] | High throughput | no | yes |
| RENT2_HUMAN | [view interactions] | High throughput | no | no |
| TMX2_HUMAN | [view interactions] | High throughput | no | yes |
| CXA1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HCD2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NDUBB_HUMAN | [view interactions] | High throughput | no | yes |
| NEB2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TAU_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LMBRL_HUMAN | [view interactions] | High throughput | no | no |
| PKHA4_HUMAN | [view interactions] | High throughput | no | yes |
| BCAR1_HUMAN | [view interactions] | High throughput | no | yes |
| INS_HUMAN | [view interactions] | High throughput | no | no |
| CFAD_HUMAN | [view interactions] | High throughput | no | no |
| FNDC5_HUMAN | [view interactions] | High throughput | no | no |
| NDUA3_HUMAN | [view interactions] | High throughput | no | yes |
| NU1M_HUMAN | [view interactions] | High throughput | no | yes |
| NDUB9_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NDUBA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NDUB4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NDUB5_HUMAN | [view interactions] | High throughput | no | yes |
| NDUB6_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NDUB7_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NDUC2_HUMAN | [view interactions] | High throughput | no | yes |
| NDUF2_HUMAN | [view interactions] | High throughput | no | yes |
| CP2J2_HUMAN | [view interactions] | High throughput | no | no |
| CREL1_HUMAN | [view interactions] | High throughput | no | yes |
| NU5M_HUMAN | [view interactions] | High throughput | no | no |
| NDUB1_HUMAN | [view interactions] | High throughput | no | yes |
| NU4M_HUMAN | [view interactions] | High throughput | no | yes |
| NU2M_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| NDUB8_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SMDC1_HUMAN | [view interactions] | High throughput | no | no |
| NDUA1_HUMAN | [view interactions] | High throughput | no | yes |
| NDUB2_HUMAN | [view interactions] | High throughput | no | yes |
| NDUB3_HUMAN | [view interactions] | High throughput | no | yes |
| NDUAA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NRP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| BASI_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RHOG_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RL38_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TIM44_HUMAN | [view interactions] | High throughput | no | yes |
| RRBP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PIN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SBDS_HUMAN | [view interactions] | High throughput | no | yes |
| RAB8A_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| PDLI5_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RBM27_HUMAN | [view interactions] | High throughput | no | yes |
| RRFM_HUMAN | [view interactions] | High throughput | no | yes |
| TAGL_HUMAN | [view interactions] | High throughput | no | no |
| PIN4_HUMAN | [view interactions] | High throughput | no | yes |
| RAGP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| UBL4A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PDLI7_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| TPX2_HUMAN | [view interactions] | High throughput | no | yes |
| UB2L3_HUMAN | [view interactions] | High throughput | no | yes |
| SNX3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ECI2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RIDA_HUMAN | [view interactions] | High throughput | no | yes |
| RBMS1_HUMAN | [view interactions] | High throughput | no | no |
| SUGP1_HUMAN | [view interactions] | High throughput | no | yes |
| QKI_HUMAN | [view interactions] | High throughput | no | no |
| PQBP1_HUMAN | [view interactions] | High throughput | no | yes |
| PAF15_HUMAN | [view interactions] | High throughput | no | no |
| TBL2_HUMAN | [view interactions] | High throughput | no | no |
| RFX5_HUMAN | [view interactions] | High throughput | no | yes |
| STX7_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MPLKI_HUMAN | [view interactions] | High throughput | no | no |
| RU1C_HUMAN | [view interactions] | High throughput | no | yes |
| SCO2_HUMAN | [view interactions] | High throughput | no | no |
| SOSB1_HUMAN | [view interactions] | High throughput | no | yes |
| RT28_HUMAN | [view interactions] | High throughput | no | yes |
| ZC11A_HUMAN | [view interactions] | High throughput | no | yes |
| CDV3_HUMAN | [view interactions] | High throughput | no | no |
| RM14_HUMAN | [view interactions] | High throughput | no | yes |
| OLA1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SRRM2_HUMAN | [view interactions] | High throughput | no | yes |
| TOM40_HUMAN | [view interactions] | High throughput | no | yes |
| RS28_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| UBC9_HUMAN | [view interactions] | High throughput | no | yes |
| P66B_HUMAN | [view interactions] | High throughput | no | yes |
| UBE4B_HUMAN | [view interactions] | High throughput | no | yes |
| VDAC3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SCP2_HUMAN | [view interactions] | High throughput | no | no |
| THIK_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NU214_HUMAN | [view interactions] | High throughput | no | no |
| CYB5_HUMAN | [view interactions] | High throughput | no | no |
| ATP5H_HUMAN | [view interactions] | High throughput | no | yes |
| SCMC1_HUMAN | [view interactions] | High throughput | no | no |
| BAP31_HUMAN | [view interactions] | High throughput | no | yes |
| ARMX2_HUMAN | [view interactions] | High throughput | no | yes |
| ATPB_HUMAN | [view interactions] | High throughput | no | yes |
| CX6A1_HUMAN | [view interactions] | High throughput | no | yes |
| ATPD_HUMAN | [view interactions] | High throughput | no | yes |
| COX41_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| IDH3A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PFD5_HUMAN | [view interactions] | High throughput | no | yes |
| UQCC2_HUMAN | [view interactions] | High throughput | no | yes |
| QCR2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ACON_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ATPG_HUMAN | [view interactions] | High throughput | no | yes |
| ATPK_HUMAN | [view interactions] | High throughput | no | yes |
| AT5L2_HUMAN | [view interactions] | High throughput | no | no |
| ATP5L_HUMAN | [view interactions] | High throughput | no | yes |
| COX6C_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CY1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| C10_HUMAN | [view interactions] | High throughput | no | yes |
| IDH3G_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NDUCR_HUMAN | [view interactions] | High throughput | no | yes |
| TIM10_HUMAN | [view interactions] | High throughput | no | yes |
| T10B_HUMAN | [view interactions] | High throughput | no | yes |
| QCR9_HUMAN | [view interactions] | High throughput | no | no |
| QCR6L_HUMAN | [view interactions] | High throughput | no | yes |
| QCR6_HUMAN | [view interactions] | High throughput | no | yes |
| CX7A2_HUMAN | [view interactions] | High throughput | no | no |
| DLDH_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ATPMK_HUMAN | [view interactions] | High throughput | no | no |
| MRM1_HUMAN | [view interactions] | High throughput | no | no |
| GRSF1_HUMAN | [view interactions] | High throughput | no | yes |
| ACAD9_HUMAN | [view interactions] | High throughput | no | yes |
| AUHM_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MTRFR_HUMAN | [view interactions] | High throughput | no | yes |
| CQ080_HUMAN | [view interactions] | High throughput | no | yes |
| C1QBP_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GAL3A_HUMAN | [view interactions] | High throughput | no | yes |
| GAL3B_HUMAN | [view interactions] | High throughput | no | yes |
| MRES1_HUMAN | [view interactions] | High throughput | no | yes |
| CH082_HUMAN | [view interactions] | High throughput | no | yes |
| MCUR1_HUMAN | [view interactions] | High throughput | no | no |
| CC90B_HUMAN | [view interactions] | High throughput | no | yes |
| CHCH1_HUMAN | [view interactions] | High throughput | no | yes |
| COX15_HUMAN | [view interactions] | High throughput | no | yes |
| CISY_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DDX28_HUMAN | [view interactions] | High throughput | no | yes |
| FAKD2_HUMAN | [view interactions] | High throughput | no | no |
| FAKD3_HUMAN | [view interactions] | High throughput | no | yes |
| FAKD5_HUMAN | [view interactions] | High throughput | no | yes |
| EFGM_HUMAN | [view interactions] | High throughput | no | yes |
| RRF2M_HUMAN | [view interactions] | High throughput | no | yes |
| HINT2_HUMAN | [view interactions] | High throughput | no | yes |
| ICT1_HUMAN | [view interactions] | High throughput | no | yes |
| LONM_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LPPRC_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MCU_HUMAN | [view interactions] | High throughput | no | yes |
| MCUB_HUMAN | [view interactions] | High throughput | no | no |
| MDHM_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MET15_HUMAN | [view interactions] | High throughput | no | no |
| MET17_HUMAN | [view interactions] | High throughput | no | yes |
| RM11_HUMAN | [view interactions] | High throughput | no | yes |
| RT12_HUMAN | [view interactions] | High throughput | no | yes |
| RT26_HUMAN | [view interactions] | High throughput | no | yes |
| MTEF3_HUMAN | [view interactions] | High throughput | no | no |
| MTG2_HUMAN | [view interactions] | High throughput | no | yes |
| IF2M_HUMAN | [view interactions] | High throughput | no | yes |
| IF3M_HUMAN | [view interactions] | High throughput | no | yes |
| RF1M_HUMAN | [view interactions] | High throughput | no | yes |
| RF1ML_HUMAN | [view interactions] | High throughput | no | yes |
| NGRN_HUMAN | [view interactions] | High throughput | no | yes |
| OTC_HUMAN | [view interactions] | High throughput | no | no |
| MPPA_HUMAN | [view interactions] | High throughput | no | yes |
| MPPB_HUMAN | [view interactions] | High throughput | no | yes |
| RUSD3_HUMAN | [view interactions] | High throughput | no | yes |
| RUSD4_HUMAN | [view interactions] | High throughput | no | yes |
| S2551_HUMAN | [view interactions] | High throughput | no | no |
| SLIRP_HUMAN | [view interactions] | High throughput | no | yes |
| SSBP_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SURF1_HUMAN | [view interactions] | High throughput | no | yes |
| TACO1_HUMAN | [view interactions] | High throughput | no | yes |
| FAKD4_HUMAN | [view interactions] | High throughput | no | yes |
| TEFM_HUMAN | [view interactions] | High throughput | no | no |
| TFAM_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TMM70_HUMAN | [view interactions] | High throughput | no | yes |
| TRUB2_HUMAN | [view interactions] | High throughput | no | yes |
| EFTS_HUMAN | [view interactions] | High throughput | no | no |
| EFTU_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| VWA8_HUMAN | [view interactions] | High throughput | no | yes |
| EXD2_HUMAN | [view interactions] | High throughput | no | yes |
| CLPP_HUMAN | [view interactions] | High throughput | no | yes |
| DNJA3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DJC15_HUMAN | [view interactions] | High throughput | no | no |
| TIM14_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| QCR7_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| MIC13_HUMAN | [view interactions] | Computational | no | yes |
| NDUC1_HUMAN | [view interactions] | Computational | no | yes |
| C560_HUMAN | [view interactions] | Computational | no | no |
| NDUAB_HUMAN | [view interactions] | Computational | no | no |
| CYB_HUMAN | [view interactions] | Computational | no | yes |
| QCR8_HUMAN | [view interactions] | Computational | no | yes |
| QCR10_HUMAN | [view interactions] | Computational | no | no |
| NU4LM_HUMAN | [view interactions] | Computational | no | no |
| PHB2_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| ATP5I_HUMAN | [view interactions] | Computational | no | yes |
| RM27_HUMAN | [view interactions] | Computational | no | yes |
| DHSD_HUMAN | [view interactions] | Computational | no | yes |
| UCRI_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| CIA30_HUMAN | [view interactions] | Computational | no | yes |
| AT5F1_HUMAN | [view interactions] | Computational | no | yes |
| ATP5J_HUMAN | [view interactions] | Computational | no | yes |
| QCR1_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| NU3M_HUMAN | [view interactions] | Computational | no | yes |
| COX7C_HUMAN | [view interactions] | Computational | no | yes |
| CX6A2_HUMAN | [view interactions] | Computational | no | no |
| NU6M_HUMAN | [view interactions] | Computational | no | no |
| RPAB5_HUMAN | [view interactions] | Computational | no | no |
| COX5A_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| COX5B_HUMAN | [view entry] [view interactions] | Computational | yes | yes |