Features Interactions Isoform Disease Linear motifs Fingerprint Network All partners

NDUS6_HUMAN

Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. [View more on UniProt]

To display all evidence describing the interaction with a partner, click on the protein name left to the bars.

Download full PS network for entry.

No data found.

No annotated instance was found. To search for linear motifs, use the ELM prediction server.

Molecular function

Term Name % Distance from the top of the tree Annotated in NDUS6_HUMAN
GO:0008324 monoatomic cation transmembrane transporter activity 33.7500 4 yes
GO:0015078 proton transmembrane transporter activity 33.7500 5 yes
GO:0022890 inorganic cation transmembrane transporter activity 33.7500 4 yes
GO:0015399 primary active transmembrane transporter activity 32.5000 4 yes
GO:0015453 oxidoreduction-driven active transmembrane transporter activity 32.5000 5 yes
GO:0022853 active monoatomic ion transmembrane transporter activity 32.5000 4 yes
GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor 27.5000 4 yes
GO:0000166 nucleotide binding 27.5000 4 no
GO:0017076 purine nucleotide binding 25.0000 5 no
GO:0043168 anion binding 25.0000 4 no
GO:0003723 RNA binding 21.2500 4 no

Biological process

Term Name % Distance from top the of the tree Annotated in NDUS6_HUMAN
GO:0022607 cellular component assembly 43.7500 4 no
GO:0009060 aerobic respiration 36.2500 6 yes
GO:0015980 energy derivation by oxidation of organic compounds 36.2500 4 yes
GO:0045333 cellular respiration 36.2500 5 yes
GO:0043933 protein-containing complex organization 36.2500 4 no
GO:0006796 phosphate-containing compound metabolic process 35.0000 4 yes
GO:0022900 electron transport chain 35.0000 4 yes
GO:0022904 respiratory electron transport chain 35.0000 5 yes
GO:0065003 protein-containing complex assembly 35.0000 5 no
GO:1901362 organic cyclic compound biosynthetic process 33.7500 4 yes
GO:1901566 organonitrogen compound biosynthetic process 33.7500 4 yes
GO:0006163 purine nucleotide metabolic process 32.5000 5 yes
GO:0006753 nucleoside phosphate metabolic process 32.5000 4 yes
GO:0009117 nucleotide metabolic process 32.5000 5 yes
GO:0019646 aerobic electron transport chain 32.5000 6 yes
GO:0034654 nucleobase-containing compound biosynthetic process 32.5000 4 yes
GO:0072521 purine-containing compound metabolic process 32.5000 4 yes
GO:0090407 organophosphate biosynthetic process 31.2500 4 yes
GO:0006164 purine nucleotide biosynthetic process 30.0000 6 yes
GO:0009150 purine ribonucleotide metabolic process 30.0000 6 yes
GO:0009152 purine ribonucleotide biosynthetic process 30.0000 7 yes
GO:0009165 nucleotide biosynthetic process 30.0000 6 yes
GO:0009259 ribonucleotide metabolic process 30.0000 5 yes
GO:0009260 ribonucleotide biosynthetic process 30.0000 6 yes
GO:0019693 ribose phosphate metabolic process 30.0000 4 yes
GO:0046390 ribose phosphate biosynthetic process 30.0000 5 yes
GO:0072522 purine-containing compound biosynthetic process 30.0000 5 yes
GO:1901137 carbohydrate derivative biosynthetic process 30.0000 4 yes
GO:1901293 nucleoside phosphate biosynthetic process 30.0000 5 yes
GO:0080090 regulation of primary metabolic process 28.7500 4 no
GO:0060255 regulation of macromolecule metabolic process 27.5000 4 no
GO:0048522 positive regulation of cellular process 27.5000 4 no
GO:0006120 mitochondrial electron transport, NADH to ubiquinone 26.2500 7 yes
GO:0006754 ATP biosynthetic process 26.2500 8 yes
GO:0009141 nucleoside triphosphate metabolic process 26.2500 5 yes
GO:0009142 nucleoside triphosphate biosynthetic process 26.2500 6 yes
GO:0009144 purine nucleoside triphosphate metabolic process 26.2500 6 yes
GO:0009145 purine nucleoside triphosphate biosynthetic process 26.2500 7 yes
GO:0009199 ribonucleoside triphosphate metabolic process 26.2500 6 yes
GO:0009201 ribonucleoside triphosphate biosynthetic process 26.2500 7 yes
GO:0009205 purine ribonucleoside triphosphate metabolic process 26.2500 7 yes
GO:0009206 purine ribonucleoside triphosphate biosynthetic process 26.2500 8 yes
GO:0015986 proton motive force-driven ATP synthesis 26.2500 9 yes
GO:0042776 proton motive force-driven mitochondrial ATP synthesis 26.2500 10 yes
GO:0046034 ATP metabolic process 26.2500 7 yes
GO:0033108 mitochondrial respiratory chain complex assembly 25.0000 6 no
GO:0031323 regulation of cellular metabolic process 25.0000 4 no
GO:0010646 regulation of cell communication 23.7500 4 no
GO:0006996 organelle organization 23.7500 4 no
GO:0010257 NADH dehydrogenase complex assembly 22.5000 6 no
GO:0032981 mitochondrial respiratory chain complex I assembly 22.5000 7 no
GO:0051246 regulation of protein metabolic process 22.5000 5 no
GO:0009966 regulation of signal transduction 22.5000 4 no
GO:0048523 negative regulation of cellular process 22.5000 4 no

Disease

No data found.

Uniprot ID Details Highest evidence Localizing into PSD HPA (protein expression in neurons)
NDUV1_HUMAN [view entry] [view interactions] Low throughput yes yes
NDUS8_HUMAN [view interactions] Low throughput no yes
NDUS7_HUMAN [view entry] [view interactions] Low throughput yes no
ACPM_HUMAN [view interactions] Low throughput no yes
NDUS4_HUMAN [view interactions] Low throughput no yes
NDUA2_HUMAN [view entry] [view interactions] Low throughput yes yes
NDUA6_HUMAN [view interactions] Low throughput no no
NDUAD_HUMAN [view entry] [view interactions] Low throughput yes yes
NDUA5_HUMAN [view entry] [view interactions] Low throughput yes yes
NDUAC_HUMAN [view entry] [view interactions] Low throughput yes yes
NDUA9_HUMAN [view entry] [view interactions] Low throughput yes yes
NDUV3_HUMAN [view interactions] Low throughput no yes
NDUS1_HUMAN [view entry] [view interactions] Low throughput yes no
NDUV2_HUMAN [view entry] [view interactions] Low throughput yes yes
NDUS2_HUMAN [view entry] [view interactions] Low throughput yes yes
NDUA7_HUMAN [view entry] [view interactions] Low throughput yes yes
NDUS3_HUMAN [view entry] [view interactions] Low throughput yes yes
NU4M_HUMAN [view interactions] High throughput no yes
RAB5C_HUMAN [view entry] [view interactions] High throughput yes yes
RMD3_HUMAN [view entry] [view interactions] High throughput yes yes
RAB7A_HUMAN [view entry] [view interactions] High throughput yes yes
VAPA_HUMAN [view entry] [view interactions] High throughput yes yes
EMC5_HUMAN [view interactions] High throughput no yes
GOT1B_HUMAN [view interactions] High throughput no yes
VAPB_HUMAN [view entry] [view interactions] High throughput yes yes
GDPD5_HUMAN [view interactions] High throughput no no
ECHD2_HUMAN [view interactions] High throughput no no
NK1R_HUMAN [view entry] [view interactions] High throughput yes no
FGL1_HUMAN [view interactions] High throughput no no
NDUA1_HUMAN [view interactions] High throughput no yes
BCAT2_HUMAN [view interactions] High throughput no no
NDUB5_HUMAN [view interactions] High throughput no yes
NDUB3_HUMAN [view interactions] High throughput no yes
NDUB1_HUMAN [view interactions] High throughput no yes
NDUB6_HUMAN [view entry] [view interactions] High throughput yes yes
NDUA3_HUMAN [view interactions] High throughput no yes
NDUB4_HUMAN [view entry] [view interactions] High throughput yes yes
NDUB8_HUMAN [view entry] [view interactions] High throughput yes yes
NDUC2_HUMAN [view interactions] High throughput no yes
NDUBA_HUMAN [view entry] [view interactions] High throughput yes yes
NU1M_HUMAN [view interactions] High throughput no yes
NU2M_HUMAN [view interactions] High throughput no no
NU5M_HUMAN [view interactions] High throughput no no
HEM1_HUMAN [view interactions] High throughput no yes
NDUB7_HUMAN [view entry] [view interactions] High throughput yes yes
NDUA8_HUMAN [view entry] [view interactions] High throughput yes yes
PCKGM_HUMAN [view interactions] High throughput no no
RBP10_HUMAN [view interactions] High throughput no no
GID4_HUMAN [view interactions] High throughput no yes
ZMY19_HUMAN [view interactions] High throughput no yes
DJC30_HUMAN [view interactions] High throughput no no
ILKAP_HUMAN [view interactions] High throughput no yes
RMD5A_HUMAN [view interactions] High throughput no yes
GID8_HUMAN [view interactions] High throughput no yes
NDUB9_HUMAN [view entry] [view interactions] High throughput yes yes
GALT6_HUMAN [view interactions] High throughput no yes
RSLAB_HUMAN [view interactions] High throughput no no
MRM3_HUMAN [view interactions] High throughput no yes
DNLI3_HUMAN [view interactions] High throughput no yes
KBL_HUMAN [view interactions] High throughput no yes
BOLA3_HUMAN [view interactions] High throughput no yes
NMES1_HUMAN [view interactions] High throughput no no
CX6B1_HUMAN [view entry] [view interactions] High throughput yes yes
NDUA4_HUMAN [view entry] [view interactions] High throughput yes yes
NIT1_HUMAN [view interactions] High throughput no yes
CHC10_HUMAN [view interactions] High throughput no yes
SDHF3_HUMAN [view interactions] High throughput no yes
ODPA_HUMAN [view entry] [view interactions] High throughput yes yes
PRIO_HUMAN [view entry] [view interactions] High throughput yes yes
HSC20_HUMAN [view interactions] High throughput no yes
ITM2B_HUMAN [view interactions] High throughput no yes
FGFR3_HUMAN [view interactions] High throughput no yes
KCNH2_HUMAN [view interactions] High throughput no no
AIFM1_HUMAN [view entry] [view interactions] High throughput yes no
AKIP_HUMAN [view interactions] High throughput no yes
CH60_HUMAN [view entry] [view interactions] High throughput yes yes
COX41_HUMAN [view entry] [view interactions] High throughput yes yes
COX14_HUMAN [view interactions] High throughput no yes
MGST3_HUMAN [view entry] [view interactions] High throughput yes yes
PDK1_HUMAN [view interactions] High throughput no yes
SCO1_HUMAN [view interactions] High throughput no yes
SFXN1_HUMAN [view entry] [view interactions] High throughput yes yes
TR61B_HUMAN [view interactions] High throughput no yes
IMP2L_HUMAN [view interactions] High throughput no yes
IMP1L_HUMAN [view interactions] High throughput no yes
PARL_HUMAN [view interactions] High throughput no yes
FHI2B_HUMAN [view interactions] High throughput no yes
MOV10_HUMAN [view interactions] High throughput no no
NXF1_HUMAN [view interactions] High throughput no yes
FBX17_HUMAN [view interactions] High throughput no no
DTX3_HUMAN [view interactions] High throughput no yes
F136A_HUMAN [view interactions] High throughput no yes
NDUBB_HUMAN [view interactions] High throughput no yes
FAHD1_HUMAN [view interactions] High throughput no yes
ARMC8_HUMAN [view interactions] High throughput no yes
MET2A_HUMAN [view interactions] High throughput no no
TRM1_HUMAN [view interactions] High throughput no yes
RNF4_HUMAN [view interactions] High throughput no yes
H4_HUMAN [view interactions] High throughput no yes
RGS14_HUMAN [view entry] [view interactions] High throughput yes yes
PKHA4_HUMAN [view interactions] High throughput no yes
HNRH1_HUMAN [view entry] [view interactions] High throughput yes yes
INS_HUMAN [view interactions] High throughput no no
CFAD_HUMAN [view interactions] High throughput no no
FNDC5_HUMAN [view interactions] High throughput no no
RIGI_HUMAN [view interactions] High throughput no yes
AROS_HUMAN [view interactions] High throughput no yes
UCRI_HUMAN [view entry] [view interactions] High throughput yes yes
MD2L1_HUMAN [view interactions] High throughput no no
MAEA_HUMAN [view interactions] High throughput no yes
MSRB2_HUMAN [view interactions] High throughput no no
C1TM_HUMAN [view entry] [view interactions] High throughput yes yes
GR6_HUMAN [view interactions] High throughput no no
CREL1_HUMAN [view interactions] High throughput no yes
COX5B_HUMAN [view entry] [view interactions] High throughput yes yes
NU3M_HUMAN [view interactions] High throughput no yes
MKLN1_HUMAN [view entry] [view interactions] High throughput yes yes
HTRA2_HUMAN [view interactions] High throughput no yes
PPCEL_HUMAN [view interactions] High throughput no yes
CK5P1_HUMAN [view interactions] High throughput no no
CP24A_HUMAN [view interactions] High throughput no no
SIR3_HUMAN [view interactions] High throughput no yes
RUSD3_HUMAN [view interactions] High throughput no yes
WDR26_HUMAN [view interactions] High throughput no yes
MD2BP_HUMAN [view interactions] High throughput no no
TBL1Y_HUMAN [view interactions] High throughput no no
HSDL2_HUMAN [view entry] [view interactions] High throughput yes yes
PUS1_HUMAN [view interactions] High throughput no yes
RANB9_HUMAN [view entry] [view interactions] High throughput yes yes
MOD5_HUMAN [view interactions] High throughput no yes
NDUAA_HUMAN [view entry] [view interactions] High throughput yes yes
DPOG1_HUMAN [view interactions] High throughput no yes
ODB2_HUMAN [view entry] [view interactions] High throughput yes yes
RSAD1_HUMAN [view interactions] High throughput no yes
RHOG_HUMAN [view entry] [view interactions] High throughput yes no
RHOA_HUMAN [view entry] [view interactions] High throughput yes yes
MYCN_HUMAN [view interactions] High throughput no no
ZRAN1_HUMAN [view interactions] High throughput no yes
TRI67_HUMAN [view interactions] High throughput no no
UBP11_HUMAN [view interactions] High throughput no yes
SMC5_HUMAN [view interactions] High throughput no yes
UBE2H_HUMAN [view interactions] High throughput no yes
OR4S2_HUMAN [view interactions] High throughput no no
ZO1_HUMAN [view entry] [view interactions] High throughput yes no
NEDD8_HUMAN [view entry] [view interactions] High throughput yes yes
FLOT1_HUMAN [view entry] [view interactions] High throughput yes yes
NNTM_HUMAN [view entry] [view interactions] High throughput yes yes
TMM65_HUMAN [view interactions] High throughput no no
SEP11_HUMAN [view entry] [view interactions] High throughput yes yes
ILF3_HUMAN [view interactions] High throughput no yes
SDHA_HUMAN [view interactions] High throughput no yes
RS12_HUMAN [view entry] [view interactions] High throughput yes yes
RALA_HUMAN [view entry] [view interactions] High throughput yes yes
COX15_HUMAN [view interactions] High throughput no yes
MPV17_HUMAN [view interactions] High throughput no no
RCN2_HUMAN [view interactions] High throughput no yes
ODPB_HUMAN [view entry] [view interactions] High throughput yes yes
C1QBP_HUMAN [view entry] [view interactions] High throughput yes yes
SCMC1_HUMAN [view interactions] High throughput no no
A4_HUMAN [view entry] [view interactions] High throughput yes yes
CALX_HUMAN [view entry] [view interactions] High throughput yes yes
ATPB_HUMAN [view interactions] High throughput no yes
PHB1_HUMAN [view entry] [view interactions] High throughput yes yes
QCR1_HUMAN [view entry] [view interactions] High throughput yes yes
IDH3A_HUMAN [view entry] [view interactions] High throughput yes yes
ATPG_HUMAN [view interactions] High throughput no yes
NDUCR_HUMAN [view interactions] High throughput no yes
ACON_HUMAN [view entry] [view interactions] High throughput yes yes
DLDH_HUMAN [view entry] [view interactions] High throughput yes yes
ADHX_HUMAN [view interactions] High throughput no yes
MRM1_HUMAN [view interactions] High throughput no no
DC1I2_HUMAN [view entry] [view interactions] High throughput yes yes
GRSF1_HUMAN [view interactions] High throughput no yes
ACAD9_HUMAN [view interactions] High throughput no yes
AUHM_HUMAN [view entry] [view interactions] High throughput yes yes
MTRFR_HUMAN [view interactions] High throughput no yes
CQ080_HUMAN [view interactions] High throughput no yes
GAL3A_HUMAN [view interactions] High throughput no yes
GAL3B_HUMAN [view interactions] High throughput no no
MRES1_HUMAN [view interactions] High throughput no yes
CH082_HUMAN [view interactions] High throughput no yes
MCUR1_HUMAN [view interactions] High throughput no no
CC90B_HUMAN [view interactions] High throughput no yes
CHCH1_HUMAN [view interactions] High throughput no yes
QOR_HUMAN [view entry] [view interactions] High throughput yes yes
CISY_HUMAN [view entry] [view interactions] High throughput yes yes
DDX28_HUMAN [view interactions] High throughput no yes
DHX30_HUMAN [view entry] [view interactions] High throughput yes yes
FAKD2_HUMAN [view interactions] High throughput no no
FAKD3_HUMAN [view interactions] High throughput no yes
FAKD5_HUMAN [view interactions] High throughput no yes
EFGM_HUMAN [view interactions] High throughput no yes
RRF2M_HUMAN [view interactions] High throughput no yes
HINT2_HUMAN [view interactions] High throughput no yes
ICT1_HUMAN [view interactions] High throughput no yes
LONM_HUMAN [view entry] [view interactions] High throughput yes yes
LPPRC_HUMAN [view entry] [view interactions] High throughput yes yes
MCU_HUMAN [view interactions] High throughput no yes
MCUB_HUMAN [view interactions] High throughput no no
MDHM_HUMAN [view entry] [view interactions] High throughput yes yes
MET15_HUMAN [view interactions] High throughput no no
MET17_HUMAN [view interactions] High throughput no yes
RM11_HUMAN [view interactions] High throughput no yes
RT12_HUMAN [view interactions] High throughput no yes
RT26_HUMAN [view interactions] High throughput no yes
RRFM_HUMAN [view interactions] High throughput no yes
MTEF3_HUMAN [view interactions] High throughput no no
FMT_HUMAN [view interactions] High throughput no yes
MTG2_HUMAN [view interactions] High throughput no yes
IF2M_HUMAN [view interactions] High throughput no yes
IF3M_HUMAN [view interactions] High throughput no yes
RF1M_HUMAN [view interactions] High throughput no yes
RF1ML_HUMAN [view interactions] High throughput no yes
NGRN_HUMAN [view interactions] High throughput no yes
OTC_HUMAN [view interactions] High throughput no no
MPPA_HUMAN [view interactions] High throughput no yes
MPPB_HUMAN [view interactions] High throughput no yes
RMND1_HUMAN [view interactions] High throughput no yes
RUSD4_HUMAN [view interactions] High throughput no yes
S2551_HUMAN [view interactions] High throughput no no
SLIRP_HUMAN [view interactions] High throughput no yes
SSBP_HUMAN [view entry] [view interactions] High throughput yes yes
SURF1_HUMAN [view interactions] High throughput no yes
TACO1_HUMAN [view interactions] High throughput no yes
FAKD4_HUMAN [view interactions] High throughput no yes
TEFM_HUMAN [view interactions] High throughput no no
TFAM_HUMAN [view entry] [view interactions] High throughput yes yes
TMM70_HUMAN [view interactions] High throughput no yes
TRUB2_HUMAN [view interactions] High throughput no yes
EFTS_HUMAN [view interactions] High throughput no no
EFTU_HUMAN [view entry] [view interactions] High throughput yes yes
VWA8_HUMAN [view interactions] High throughput no yes
EXD2_HUMAN [view interactions] High throughput no yes
CLPP_HUMAN [view interactions] High throughput no yes
DNJA3_HUMAN [view entry] [view interactions] High throughput yes yes
DJC15_HUMAN [view interactions] High throughput no no
TIM14_HUMAN [view entry] [view interactions] High throughput yes yes
DJC28_HUMAN [view interactions] High throughput no yes
GRP75_HUMAN [view entry] [view interactions] High throughput yes yes
SYAM_HUMAN [view interactions] High throughput no yes
COX8A_HUMAN [view interactions] High throughput no yes
TRAP1_HUMAN [view entry] [view interactions] High throughput yes yes
ETFB_HUMAN [view entry] [view interactions] High throughput yes yes
M3K7_HUMAN [view interactions] High throughput no yes
MK06_HUMAN [view interactions] High throughput no yes
JIP2_HUMAN [view entry] [view interactions] High throughput yes no
GDNF_HUMAN [view interactions] High throughput no yes
NDUS5_HUMAN [view interactions] High throughput no yes
NDUAB_HUMAN [view interactions] High throughput no no