HSDL2_HUMAN
Evidence for PS localization
Functions
Has apparently no steroid dehydrogenase activity. [View more on UniProt]
Protein features
Binary interactions with known binding regions
Interacting region for partners were not defined.
Network
Isoforms
Disease-causing germline mutations
No data found.
Linear motifs
No annotated instance was found. To search for linear motifs, use the ELM prediction server.
Fingerprint
Molecular function
| Term | Name | % | Distance from the top of the tree | Annotated in HSDL2_HUMAN |
|---|---|---|---|---|
| GO:0000166 | nucleotide binding | 36.5385 | 4 | no |
| GO:0043168 | anion binding | 34.6154 | 4 | no |
| GO:0017076 | purine nucleotide binding | 32.6923 | 5 | no |
| GO:0003723 | RNA binding | 28.8462 | 4 | no |
| GO:0032555 | purine ribonucleotide binding | 28.8462 | 4 | no |
| GO:0035639 | purine ribonucleoside triphosphate binding | 25.0000 | 4 | no |
| GO:0016462 | pyrophosphatase activity | 23.0769 | 5 | no |
| GO:0016818 | hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides | 23.0769 | 4 | no |
| GO:0017111 | ribonucleoside triphosphate phosphatase activity | 23.0769 | 6 | no |
Biological process
| Term | Name | % | Distance from top the of the tree | Annotated in HSDL2_HUMAN |
|---|---|---|---|---|
| GO:0060255 | regulation of macromolecule metabolic process | 38.4615 | 4 | no |
| GO:0009893 | positive regulation of metabolic process | 36.5385 | 4 | no |
| GO:0048522 | positive regulation of cellular process | 36.5385 | 4 | no |
| GO:0080090 | regulation of primary metabolic process | 36.5385 | 4 | no |
| GO:0031323 | regulation of cellular metabolic process | 36.5385 | 4 | no |
| GO:0019752 | carboxylic acid metabolic process | 34.6154 | 5 | no |
| GO:0043436 | oxoacid metabolic process | 34.6154 | 4 | no |
| GO:0009889 | regulation of biosynthetic process | 32.6923 | 4 | no |
| GO:0010468 | regulation of gene expression | 32.6923 | 6 | no |
| GO:0010556 | regulation of macromolecule biosynthetic process | 32.6923 | 5 | no |
| GO:0031326 | regulation of cellular biosynthetic process | 32.6923 | 5 | no |
| GO:0048523 | negative regulation of cellular process | 32.6923 | 4 | no |
| GO:0010604 | positive regulation of macromolecule metabolic process | 30.7692 | 5 | no |
| GO:0006996 | organelle organization | 28.8462 | 4 | no |
| GO:0022607 | cellular component assembly | 28.8462 | 4 | no |
| GO:0009966 | regulation of signal transduction | 28.8462 | 4 | no |
| GO:0010646 | regulation of cell communication | 28.8462 | 4 | no |
| GO:0019219 | regulation of nucleobase-containing compound metabolic process | 26.9231 | 5 | no |
| GO:0032787 | monocarboxylic acid metabolic process | 26.9231 | 6 | no |
| GO:1902531 | regulation of intracellular signal transduction | 26.9231 | 5 | no |
| GO:0031325 | positive regulation of cellular metabolic process | 26.9231 | 5 | no |
| GO:0051252 | regulation of RNA metabolic process | 25.0000 | 5 | no |
| GO:0016054 | organic acid catabolic process | 25.0000 | 4 | no |
| GO:0046395 | carboxylic acid catabolic process | 25.0000 | 5 | no |
| GO:0051246 | regulation of protein metabolic process | 25.0000 | 5 | no |
| GO:0051128 | regulation of cellular component organization | 23.0769 | 4 | no |
| GO:0006796 | phosphate-containing compound metabolic process | 23.0769 | 4 | no |
| GO:0006355 | regulation of DNA-templated transcription | 23.0769 | 7 | no |
| GO:0048584 | positive regulation of response to stimulus | 23.0769 | 4 | no |
| GO:0051240 | positive regulation of multicellular organismal process | 23.0769 | 4 | no |
| GO:2001141 | regulation of RNA biosynthetic process | 23.0769 | 6 | no |
| GO:0009891 | positive regulation of biosynthetic process | 23.0769 | 5 | no |
| GO:0010557 | positive regulation of macromolecule biosynthetic process | 23.0769 | 6 | no |
| GO:0031328 | positive regulation of cellular biosynthetic process | 23.0769 | 6 | no |
| GO:0009967 | positive regulation of signal transduction | 21.1538 | 5 | no |
| GO:0010647 | positive regulation of cell communication | 21.1538 | 5 | no |
| GO:0010648 | negative regulation of cell communication | 21.1538 | 5 | no |
| GO:0023056 | positive regulation of signaling | 21.1538 | 4 | no |
| GO:0023057 | negative regulation of signaling | 21.1538 | 4 | no |
| GO:0006631 | fatty acid metabolic process | 21.1538 | 4 | no |
| GO:0030258 | lipid modification | 21.1538 | 4 | no |
| GO:0009892 | negative regulation of metabolic process | 21.1538 | 4 | no |
| GO:0043067 | regulation of programmed cell death | 21.1538 | 4 | no |
Disease
No data found.
All partners
| Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
|---|---|---|---|---|
| PRKN_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| BUB1_HUMAN | [view interactions] | High throughput | no | no |
| MIPEP_HUMAN | [view interactions] | High throughput | no | yes |
| HERC2_HUMAN | [view interactions] | High throughput | no | yes |
| PAR2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NEUL4_HUMAN | [view interactions] | High throughput | no | yes |
| NPS3A_HUMAN | [view interactions] | High throughput | no | yes |
| ATX3_HUMAN | [view interactions] | High throughput | no | yes |
| ZUP1_HUMAN | [view interactions] | High throughput | no | yes |
| CXA1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| EGLN3_HUMAN | [view interactions] | High throughput | no | no |
| U5S1_HUMAN | [view interactions] | High throughput | no | yes |
| AAR2_HUMAN | [view interactions] | High throughput | no | no |
| PIHD1_HUMAN | [view interactions] | High throughput | no | yes |
| ESR2_HUMAN | [view interactions] | High throughput | no | no |
| RECQ4_HUMAN | [view interactions] | High throughput | no | yes |
| NR2C2_HUMAN | [view interactions] | High throughput | no | yes |
| BIRC3_HUMAN | [view interactions] | High throughput | no | no |
| LMBRL_HUMAN | [view interactions] | High throughput | no | no |
| SIR3_HUMAN | [view interactions] | High throughput | no | yes |
| PKHA4_HUMAN | [view interactions] | High throughput | no | yes |
| ANLN_HUMAN | [view interactions] | High throughput | no | yes |
| KI20A_HUMAN | [view interactions] | High throughput | no | yes |
| UFL1_HUMAN | [view interactions] | High throughput | no | yes |
| WDR5_HUMAN | [view interactions] | High throughput | no | no |
| CALL3_HUMAN | [view interactions] | High throughput | no | yes |
| F133A_HUMAN | [view interactions] | High throughput | no | no |
| PRPS1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| LHPL4_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| NDUS6_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RHOA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RHOG_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CAPZB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PSB10_HUMAN | [view interactions] | High throughput | no | no |
| ZRAN1_HUMAN | [view interactions] | High throughput | no | yes |
| PARPT_HUMAN | [view interactions] | High throughput | no | no |
| TRI67_HUMAN | [view interactions] | High throughput | no | no |
| FBW1A_HUMAN | [view interactions] | High throughput | no | yes |
| FND3A_HUMAN | [view interactions] | High throughput | no | yes |
| PTEN_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NDUA8_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SF01_HUMAN | [view interactions] | High throughput | no | yes |
| TAGL2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| TRAP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ADRO_HUMAN | [view interactions] | High throughput | no | no |
| THIM_HUMAN | [view interactions] | High throughput | no | yes |
| MMSA_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| DECR_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ETFD_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PECR_HUMAN | [view interactions] | High throughput | no | yes |
| ACD11_HUMAN | [view interactions] | High throughput | no | yes |
| ACOX1_HUMAN | [view interactions] | High throughput | no | yes |
| DR4L2_HUMAN | [view interactions] | High throughput | no | no |
| DHRS4_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ECI2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HACL1_HUMAN | [view interactions] | High throughput | no | no |
| ECHA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ECHB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ACADL_HUMAN | [view interactions] | High throughput | no | no |
| ACADV_HUMAN | [view interactions] | High throughput | no | yes |
| CPT2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CACP_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ECH1_HUMAN | [view interactions] | High throughput | no | yes |
| ECI1_HUMAN | [view interactions] | High throughput | no | yes |
| DHB4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PTGR3_HUMAN | [view interactions] | High throughput | no | yes |
| ECHP_HUMAN | [view interactions] | High throughput | no | no |
| ETFA_HUMAN | [view interactions] | High throughput | no | yes |
| ETFB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PEX7_HUMAN | [view interactions] | High throughput | no | yes |
| PEX14_HUMAN | [view interactions] | High throughput | no | yes |
| RAB14_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RC3H1_HUMAN | [view interactions] | High throughput | no | yes |
| PIN4_HUMAN | [view interactions] | High throughput | no | yes |
| MRM1_HUMAN | [view interactions] | High throughput | no | no |
| ACAD9_HUMAN | [view interactions] | High throughput | no | yes |
| AUHM_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| C1QBP_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GAL3A_HUMAN | [view interactions] | High throughput | no | yes |
| GAL3B_HUMAN | [view interactions] | High throughput | no | no |
| MRES1_HUMAN | [view interactions] | High throughput | no | yes |
| MCUR1_HUMAN | [view interactions] | High throughput | no | no |
| CISY_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FAKD5_HUMAN | [view interactions] | High throughput | no | yes |
| EFGM_HUMAN | [view interactions] | High throughput | no | yes |
| HINT2_HUMAN | [view interactions] | High throughput | no | yes |
| ICT1_HUMAN | [view interactions] | High throughput | no | yes |
| LONM_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LPPRC_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MDHM_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MET17_HUMAN | [view interactions] | High throughput | no | yes |
| MIC26_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RT26_HUMAN | [view interactions] | High throughput | no | yes |
| MTEF3_HUMAN | [view interactions] | High throughput | no | no |
| IF2M_HUMAN | [view interactions] | High throughput | no | yes |
| IF3M_HUMAN | [view interactions] | High throughput | no | yes |
| RF1M_HUMAN | [view interactions] | High throughput | no | yes |
| RF1ML_HUMAN | [view interactions] | High throughput | no | yes |
| MPPA_HUMAN | [view interactions] | High throughput | no | yes |
| MPPB_HUMAN | [view interactions] | High throughput | no | yes |
| RMND1_HUMAN | [view interactions] | High throughput | no | yes |
| RUSD3_HUMAN | [view interactions] | High throughput | no | yes |
| RUSD4_HUMAN | [view interactions] | High throughput | no | yes |
| SSBP_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TACO1_HUMAN | [view interactions] | High throughput | no | yes |
| FAKD4_HUMAN | [view interactions] | High throughput | no | yes |
| TFAM_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TMM70_HUMAN | [view interactions] | High throughput | no | yes |
| TRUB2_HUMAN | [view interactions] | High throughput | no | yes |
| EFTS_HUMAN | [view interactions] | High throughput | no | no |
| EFTU_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| VWA8_HUMAN | [view interactions] | High throughput | no | yes |
| EXD2_HUMAN | [view interactions] | High throughput | no | yes |
| CLPP_HUMAN | [view interactions] | High throughput | no | yes |
| GCR_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SYAM_HUMAN | [view interactions] | High throughput | no | yes |
| ADAS_HUMAN | [view interactions] | High throughput | no | yes |
| COX8A_HUMAN | [view interactions] | High throughput | no | yes |
| NUP43_HUMAN | [view interactions] | High throughput | no | yes |
| NUP35_HUMAN | [view interactions] | High throughput | no | yes |
| GBB2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RFA1_HUMAN | [view interactions] | High throughput | no | yes |
| RFA2_HUMAN | [view interactions] | High throughput | no | yes |
| RFA3_HUMAN | [view interactions] | High throughput | no | yes |
| GBRAP_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| MK06_HUMAN | [view interactions] | High throughput | no | yes |
| HDAC1_HUMAN | [view interactions] | High throughput | no | no |
| HSC20_HUMAN | [view interactions] | High throughput | no | yes |
| COQ9_HUMAN | [view interactions] | High throughput | no | yes |
| LRRK2_HUMAN | [view interactions] | High throughput | no | yes |
| KPCB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PPM1A_HUMAN | [view interactions] | High throughput | no | yes |
| RASH_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| DLDH_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ODO2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ODPA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ENOA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| IKKE_HUMAN | [view interactions] | High throughput | no | yes |
| JUN_HUMAN | [view interactions] | High throughput | no | yes |
| PKHA7_HUMAN | [view interactions] | High throughput | no | yes |
| HDAC5_HUMAN | [view interactions] | High throughput | no | yes |
| NPHP1_HUMAN | [view interactions] | High throughput | no | yes |
| FTM_HUMAN | [view interactions] | High throughput | no | yes |
| TECT3_HUMAN | [view interactions] | High throughput | no | yes |
| CNTRL_HUMAN | [view interactions] | High throughput | no | yes |
| CATA_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CH60_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MGST3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PDK1_HUMAN | [view interactions] | High throughput | no | yes |
| TR61B_HUMAN | [view interactions] | High throughput | no | yes |
| RASK_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RASN_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| FHI1B_HUMAN | [view interactions] | High throughput | no | yes |
| FHI2B_HUMAN | [view interactions] | High throughput | no | yes |
| CFTR_HUMAN | [view interactions] | High throughput | no | no |
| XRCC4_HUMAN | [view interactions] | High throughput | no | yes |
| DNJC9_HUMAN | [view interactions] | High throughput | no | yes |
| DNPEP_HUMAN | [view interactions] | High throughput | no | yes |
| KIF3A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FBX6_HUMAN | [view interactions] | High throughput | no | yes |
| PEX5_HUMAN | [view interactions] | High throughput | no | yes |
| ADRB2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |