Features Interactions Isoform Disease Linear motifs Fingerprint Network All partners

RAB14_HUMAN

Involved in membrane trafficking between the Golgi complex and endosomes during early embryonic development. Regulates the Golgi to endosome transport of FGFR-containing vesicles during early development, a key process for developing basement membrane and epiblast and primitive endoderm lineages during early postimplantation development. May act by modulating the kinesin KIF16B-cargo association to endosomes . Regulates, together with its guanine nucleotide exchange factor DENND6A, the specific endocytic transport of ADAM10, N-cadherin/CDH2 shedding and cell-cell adhesion. [View more on UniProt]

Interacting region for partners were not defined.

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No data found.

No annotated instance was found. To search for linear motifs, use the ELM prediction server.

Molecular function

Term Name % Distance from the top of the tree Annotated in RAB14_HUMAN
GO:0017076 purine nucleotide binding 27.6316 4 yes
GO:0032555 purine ribonucleotide binding 27.6316 4 yes
GO:0035639 purine ribonucleoside triphosphate binding 27.6316 4 yes
GO:0016462 pyrophosphatase activity 23.6842 5 yes
GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 23.6842 4 yes
GO:0017111 ribonucleoside triphosphate phosphatase activity 23.6842 6 yes
GO:0003924 GTPase activity 19.7368 7 yes
GO:0005525 GTP binding 19.7368 5 yes
GO:0019001 guanyl nucleotide binding 19.7368 5 yes
GO:0032561 guanyl ribonucleotide binding 19.7368 5 yes
GO:0019003 GDP binding 14.4737 4 yes
GO:0017022 myosin binding 3.9474 4 yes

Biological process

Term Name % Distance from top the of the tree Annotated in RAB14_HUMAN
GO:0008104 protein localization 61.8421 4 yes
GO:0048522 positive regulation of cellular process 57.8947 4 no
GO:0071702 organic substance transport 48.6842 4 yes
GO:0071705 nitrogen compound transport 48.6842 4 yes
GO:0015031 protein transport 47.3684 4 yes
GO:0006996 organelle organization 46.0526 4 yes
GO:0016192 vesicle-mediated transport 43.4211 4 yes
GO:0031323 regulation of cellular metabolic process 43.4211 4 no
GO:0022607 cellular component assembly 40.7895 4 yes
GO:0051128 regulation of cellular component organization 40.7895 4 no
GO:0051049 regulation of transport 39.4737 4 no
GO:0060255 regulation of macromolecule metabolic process 38.1579 4 no
GO:0048523 negative regulation of cellular process 36.8421 4 no
GO:0009893 positive regulation of metabolic process 35.5263 4 no
GO:0010646 regulation of cell communication 35.5263 4 no
GO:0080090 regulation of primary metabolic process 34.2105 4 no
GO:0009966 regulation of signal transduction 32.8947 4 no
GO:0051171 regulation of nitrogen compound metabolic process 32.8947 4 no
GO:0010604 positive regulation of macromolecule metabolic process 31.5789 5 no
GO:0006886 intracellular protein transport 28.9474 4 yes
GO:0048584 positive regulation of response to stimulus 27.6316 4 no
GO:0051246 regulation of protein metabolic process 27.6316 5 no
GO:0060341 regulation of cellular localization 26.3158 4 yes
GO:0023056 positive regulation of signaling 26.3158 4 no
GO:0033043 regulation of organelle organization 26.3158 5 no
GO:0051130 positive regulation of cellular component organization 26.3158 5 no
GO:0031325 positive regulation of cellular metabolic process 25.0000 5 no
GO:0051173 positive regulation of nitrogen compound metabolic process 25.0000 5 no
GO:0044087 regulation of cellular component biogenesis 25.0000 4 no
GO:0032880 regulation of protein localization 23.6842 5 yes
GO:0009967 positive regulation of signal transduction 22.3684 5 no
GO:0010647 positive regulation of cell communication 22.3684 5 no
GO:0060627 regulation of vesicle-mediated transport 21.0526 4 no
GO:0051050 positive regulation of transport 21.0526 4 no
GO:0009894 regulation of catabolic process 21.0526 4 no
GO:0030030 cell projection organization 21.0526 4 no
GO:0071310 cellular response to organic substance 21.0526 4 no
GO:0031344 regulation of cell projection organization 21.0526 5 no
GO:0048193 Golgi vesicle transport 19.7368 5 yes
GO:0016050 vesicle organization 17.1053 5 yes
GO:0070925 organelle assembly 17.1053 5 yes
GO:0098876 vesicle-mediated transport to the plasma membrane 14.4737 4 yes
GO:0006892 post-Golgi vesicle-mediated transport 13.1579 6 yes
GO:2000026 regulation of multicellular organismal development 13.1579 4 yes
GO:0016197 endosomal transport 9.2105 4 yes
GO:0007033 vacuole organization 7.8947 5 yes
GO:0016482 cytosolic transport 7.8947 4 yes
GO:0032456 endocytic recycling 3.9474 5 yes
GO:0042742 defense response to bacterium 3.9474 4 yes
GO:0007040 lysosome organization 2.6316 7 yes
GO:0007167 enzyme-linked receptor protein signaling pathway 2.6316 4 yes
GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway 2.6316 5 yes
GO:0045995 regulation of embryonic development 2.6316 5 yes
GO:0080171 lytic vacuole organization 2.6316 6 yes
GO:0090382 phagosome maturation 2.6316 5 yes

Disease

No data found.

Uniprot ID Details Highest evidence Localizing into PSD HPA (protein expression in neurons)
RBNS5_HUMAN [view interactions] Low throughput no yes
TBCD1_HUMAN [view interactions] Low throughput no no
TBCD4_HUMAN [view interactions] Low throughput no yes
OCRL_HUMAN [view interactions] Low throughput no yes
NISCH_HUMAN [view interactions] Low throughput no yes
AP1G1_HUMAN [view entry] [view interactions] Low throughput yes yes
EEA1_HUMAN [view entry] [view interactions] Low throughput yes yes
HGS_HUMAN [view entry] [view interactions] Low throughput yes yes
CATA_HUMAN [view entry] [view interactions] Low throughput yes no
ECHP_HUMAN [view interactions] Low throughput no no
RUFY1_HUMAN [view interactions] Low throughput no yes
OPTN_HUMAN [view interactions] Low throughput no yes
RFIP5_HUMAN [view entry] [view interactions] Low throughput yes yes
RFIP1_HUMAN [view interactions] Low throughput no yes
ANXA2_HUMAN [view entry] [view interactions] Low throughput yes no
UB2R1_HUMAN [view interactions] High throughput no yes
HEXI1_HUMAN [view interactions] High throughput no yes
NEB2_HUMAN [view entry] [view interactions] High throughput yes yes
GLP1R_HUMAN [view interactions] High throughput no no
AAPK1_HUMAN [view interactions] High throughput no no
VIR_HUMAN [view interactions] High throughput no yes
FLCN_HUMAN [view interactions] High throughput no yes
NR2C2_HUMAN [view interactions] High throughput no yes
NHLC2_HUMAN [view interactions] High throughput no yes
TIA1_HUMAN [view interactions] High throughput no no
BAG6_HUMAN [view entry] [view interactions] High throughput yes yes
DUS6_HUMAN [view interactions] High throughput no yes
LMBRL_HUMAN [view interactions] High throughput no no
WWP1_HUMAN [view interactions] High throughput no yes
EMC1_HUMAN [view interactions] High throughput no yes
EMC4_HUMAN [view interactions] High throughput no yes
ANLN_HUMAN [view interactions] High throughput no yes
KIF14_HUMAN [view interactions] High throughput no no
KI20A_HUMAN [view interactions] High throughput no yes
NPC1_HUMAN [view interactions] High throughput no yes
CFAD_HUMAN [view interactions] High throughput no no
FNDC5_HUMAN [view interactions] High throughput no no
BAP31_HUMAN [view interactions] High throughput no yes
APR_HUMAN [view interactions] High throughput no yes
WDR5_HUMAN [view interactions] High throughput no no
LSM1_HUMAN [view interactions] High throughput no no
STX17_HUMAN [view interactions] High throughput no yes
GPM6A_HUMAN [view entry] [view interactions] High throughput yes no
FIS1_HUMAN [view entry] [view interactions] High throughput yes yes
AATC_HUMAN [view entry] [view interactions] High throughput yes yes
LDAF1_HUMAN [view interactions] High throughput no yes
FFAR1_HUMAN [view interactions] High throughput no no
PLCA_HUMAN [view interactions] High throughput no yes
OSGEP_HUMAN [view interactions] High throughput no yes
CR021_HUMAN [view interactions] High throughput no no
THAP8_HUMAN [view interactions] High throughput no yes
DERL2_HUMAN [view interactions] High throughput no yes
MMTA2_HUMAN [view interactions] High throughput no yes
CCR1_HUMAN [view interactions] High throughput no no
TIDC1_HUMAN [view interactions] High throughput no yes
SSUH2_HUMAN [view interactions] High throughput no no
PAIRB_HUMAN [view interactions] High throughput no yes
PINK1_HUMAN [view interactions] High throughput no yes
SYT6_HUMAN [view entry] [view interactions] High throughput yes no
SPRTN_HUMAN [view interactions] High throughput no yes
FSCN1_HUMAN [view entry] [view interactions] High throughput yes yes
NRP1_HUMAN [view entry] [view interactions] High throughput yes yes
BASI_HUMAN [view entry] [view interactions] High throughput yes no
CCNF_HUMAN [view interactions] High throughput no no
TM192_HUMAN [view interactions] High throughput no yes
LEG8_HUMAN [view entry] [view interactions] High throughput yes yes
RHOA_HUMAN [view entry] [view interactions] High throughput yes yes
RAE1_HUMAN [view interactions] High throughput no yes
GDIB_HUMAN [view entry] [view interactions] High throughput yes yes
LAMP1_HUMAN [view interactions] High throughput no yes
LTOR2_HUMAN [view interactions] High throughput no yes
TOM40_HUMAN [view interactions] High throughput no yes
TFR1_HUMAN [view interactions] High throughput no yes
TSN6_HUMAN [view interactions] High throughput no yes
NSF_HUMAN [view entry] [view interactions] High throughput yes yes
RAE2_HUMAN [view interactions] High throughput no yes
VDAC1_HUMAN [view entry] [view interactions] High throughput yes yes
VATB2_HUMAN [view entry] [view interactions] High throughput yes yes
RAB4A_HUMAN [view entry] [view interactions] High throughput yes no
CD81_HUMAN [view interactions] High throughput no no
SC31A_HUMAN [view entry] [view interactions] High throughput yes yes
S6A15_HUMAN [view interactions] High throughput no yes
NRBF2_HUMAN [view interactions] High throughput no yes
PRP19_HUMAN [view interactions] High throughput no yes
TMCO1_HUMAN [view interactions] High throughput no yes
ENPP4_HUMAN [view interactions] High throughput no yes
VPP2_HUMAN [view interactions] High throughput no yes
DYHC1_HUMAN [view entry] [view interactions] High throughput yes yes
VP13C_HUMAN [view interactions] High throughput no yes
URFB1_HUMAN [view interactions] High throughput no no
RAB1A_HUMAN [view entry] [view interactions] High throughput yes yes
RAB1B_HUMAN [view entry] [view interactions] High throughput yes yes
RAB7A_HUMAN [view entry] [view interactions] High throughput yes yes
RTN4_HUMAN [view entry] [view interactions] High throughput yes yes
SCAM1_HUMAN [view interactions] High throughput no no
SCAM2_HUMAN [view interactions] High throughput no no
SCAM4_HUMAN [view interactions] High throughput no yes
SEC13_HUMAN [view entry] [view interactions] High throughput yes yes
SPTC1_HUMAN [view interactions] High throughput no yes
STX12_HUMAN [view entry] [view interactions] High throughput yes yes
STX7_HUMAN [view entry] [view interactions] High throughput yes yes
TMEDA_HUMAN [view interactions] High throughput no yes
VAMP3_HUMAN [view entry] [view interactions] High throughput yes no
TRPC6_HUMAN [view interactions] High throughput no no
FAS_HUMAN [view entry] [view interactions] High throughput yes no
A4_HUMAN [view entry] [view interactions] High throughput yes yes
BIP_HUMAN [view entry] [view interactions] High throughput yes yes
MRP2_HUMAN [view interactions] High throughput no no
LTOR3_HUMAN [view interactions] High throughput no yes
HACL2_HUMAN [view interactions] High throughput no yes
UCRI_HUMAN [view entry] [view interactions] High throughput yes yes
ILF3_HUMAN [view interactions] High throughput no yes
TACC3_HUMAN [view entry] [view interactions] High throughput yes yes
HNRPF_HUMAN [view interactions] High throughput no yes
VATC1_HUMAN [view entry] [view interactions] High throughput yes yes
CDC42_HUMAN [view entry] [view interactions] High throughput yes yes
SDHA_HUMAN [view interactions] High throughput no yes
RAB5A_HUMAN [view entry] [view interactions] High throughput yes yes
AGR2_HUMAN [view interactions] High throughput no no
RFFL_HUMAN [view interactions] High throughput no yes
AKAP1_HUMAN [view entry] [view interactions] High throughput yes yes
ARF6_HUMAN [view entry] [view interactions] High throughput yes yes
LAMP2_HUMAN [view interactions] High throughput no yes
LTOR1_HUMAN [view entry] [view interactions] High throughput yes yes
RAB2A_HUMAN [view entry] [view interactions] High throughput yes yes
RAB5C_HUMAN [view entry] [view interactions] High throughput yes yes
MLP3B_HUMAN [view interactions] High throughput no yes
NBR1_HUMAN [view interactions] High throughput no yes
CACO2_HUMAN [view interactions] High throughput no yes
SYNPO_HUMAN [view entry] [view interactions] High throughput yes no
GLUT4_HUMAN [view interactions] High throughput no no
FTM_HUMAN [view interactions] High throughput no yes
IQCB1_HUMAN [view interactions] High throughput no no
ATF2_HUMAN [view interactions] High throughput no yes
GDIA_HUMAN [view entry] [view interactions] High throughput yes yes
RENR_HUMAN [view entry] [view interactions] High throughput yes yes
ACTB_HUMAN [view entry] [view interactions] High throughput yes no
FLNB_HUMAN [view interactions] High throughput no no
CEP43_HUMAN [view interactions] High throughput no no
ATLA3_HUMAN [view interactions] High throughput no no
PLAK_HUMAN [view entry] [view interactions] High throughput yes yes
RAB4B_HUMAN [view entry] [view interactions] High throughput yes no
ACATN_HUMAN [view interactions] High throughput no yes
KSR1_HUMAN [view interactions] High throughput no yes
RAB2B_HUMAN [view interactions] High throughput no no
XPO7_HUMAN [view entry] [view interactions] High throughput yes yes
ZDHC5_HUMAN [view entry] [view interactions] High throughput yes yes
SHAN3_HUMAN [view entry] [view interactions] High throughput yes no
TAGL_HUMAN [view interactions] High throughput no no
RB39A_HUMAN [view interactions] High throughput no no
AHR_HUMAN [view interactions] High throughput no yes
CFTR_HUMAN [view interactions] High throughput no no
VHL_HUMAN [view entry] [view interactions] High throughput yes yes
IKKE_HUMAN [view interactions] High throughput no yes
DUSTY_HUMAN [view interactions] High throughput no yes
HLAB_HUMAN [view interactions] High throughput no yes
TSC1_HUMAN [view entry] [view interactions] High throughput yes yes
DLG4_HUMAN [view entry] [view interactions] High throughput yes yes
CD177_HUMAN [view interactions] High throughput no no
TX101_HUMAN [view interactions] High throughput no no
ITM2B_HUMAN [view interactions] High throughput no yes
RYBP_HUMAN [view interactions] High throughput no no
LAMP3_HUMAN [view interactions] High throughput no no
EXOC5_HUMAN [view entry] [view interactions] High throughput yes yes
3BP5L_HUMAN [view interactions] High throughput no yes
FA71C_HUMAN [view interactions] High throughput no no
ADRB2_HUMAN [view entry] [view interactions] High throughput yes no
CNTRL_HUMAN [view interactions] High throughput no yes
FAKD3_HUMAN [view interactions] High throughput no yes
ASPH_HUMAN [view interactions] High throughput no yes
TGON2_HUMAN [view interactions] High throughput no yes
RASK_HUMAN [view entry] [view interactions] High throughput yes no
RASN_HUMAN [view entry] [view interactions] High throughput yes no
GLCM_HUMAN [view interactions] High throughput no yes
COMT_HUMAN [view entry] [view interactions] High throughput yes yes
CCHL_HUMAN [view interactions] High throughput no yes
SMUF2_HUMAN [view interactions] High throughput no yes
SUMO2_HUMAN [view interactions] High throughput no yes
SUMO3_HUMAN [view interactions] High throughput no yes
TERA_HUMAN [view entry] [view interactions] High throughput yes yes
UBL4A_HUMAN [view entry] [view interactions] High throughput yes yes
UBC_HUMAN [view entry] [view interactions] High throughput yes yes
RFA3_HUMAN [view interactions] High throughput no yes
RFA2_HUMAN [view interactions] High throughput no yes
RFA1_HUMAN [view interactions] High throughput no yes
CUL7_HUMAN [view interactions] High throughput no yes
CCDC8_HUMAN [view interactions] High throughput no yes
EED_HUMAN [view interactions] High throughput no yes
S2541_HUMAN [view interactions] High throughput no no
HAX1_HUMAN [view interactions] High throughput no no
NUFP1_HUMAN [view interactions] High throughput no yes
DGUOK_HUMAN [view interactions] High throughput no yes
ACL6A_HUMAN [view interactions] High throughput no yes
UNK_HUMAN [view interactions] High throughput no yes
IF16_HUMAN [view interactions] High throughput no no
WDTC1_HUMAN [view interactions] High throughput no yes
DUS22_HUMAN [view interactions] High throughput no yes
FACD2_HUMAN [view interactions] High throughput no no
KCD12_HUMAN [view entry] [view interactions] High throughput yes no
FGFR1_HUMAN [view interactions] High throughput no yes
PIHD1_HUMAN [view interactions] High throughput no yes
RNF4_HUMAN [view interactions] High throughput no yes
DEN6B_HUMAN [view interactions] Computational no no
EXOC2_HUMAN [view entry] [view interactions] Computational yes no
RALA_HUMAN [view entry] [view interactions] Computational yes yes
EXOC4_HUMAN [view entry] [view interactions] Computational yes yes
EXOC6_HUMAN [view entry] [view interactions] Computational yes yes
1433G_HUMAN [view entry] [view interactions] Computational yes yes
EXOC3_HUMAN [view entry] [view interactions] Computational yes no
DEN6A_HUMAN [view interactions] Computational no yes
EXOC7_HUMAN [view entry] [view interactions] Computational yes yes
EXOC8_HUMAN [view entry] [view interactions] Computational yes yes
LCAP_HUMAN [view interactions] Computational no yes
EXOC1_HUMAN [view entry] [view interactions] Computational yes yes