SEC13_HUMAN
Evidence for PS localization
Functions
As a component of the GATOR subcomplex GATOR2, functions within the amino acid-sensing branch of the TORC1 signaling pathway. Indirectly activates mTORC1 and the TORC1 signaling pathway through the inhibition of the GATOR1 subcomplex (PubMed). It is negatively regulated by the upstream amino acid sensors SESN2 and CASTOR1 (PubMed, PubMed). [View more on UniProt]
Protein features
Binary interactions with known binding regions
To display all evidence describing the interaction with a partner, click on the protein name left to the bars.
Network
Isoforms
Disease-causing germline mutations
No data found.
Linear motifs
No annotated instance was found. To search for linear motifs, use the ELM prediction server.
Fingerprint
Molecular function
| Term | Name | % | Distance from the top of the tree | Annotated in SEC13_HUMAN |
|---|---|---|---|---|
| GO:0017076 | purine nucleotide binding | 39.2857 | 4 | no |
| GO:0032555 | purine ribonucleotide binding | 38.0952 | 4 | no |
| GO:0035639 | purine ribonucleoside triphosphate binding | 38.0952 | 4 | no |
| GO:0016462 | pyrophosphatase activity | 27.3810 | 5 | no |
| GO:0016818 | hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides | 27.3810 | 4 | no |
| GO:0017111 | ribonucleoside triphosphate phosphatase activity | 27.3810 | 6 | no |
| GO:0030554 | adenyl nucleotide binding | 27.3810 | 5 | no |
| GO:0005524 | ATP binding | 26.1905 | 5 | no |
| GO:0032559 | adenyl ribonucleotide binding | 26.1905 | 5 | no |
| GO:0003723 | RNA binding | 23.8095 | 4 | no |
Biological process
| Term | Name | % | Distance from top the of the tree | Annotated in SEC13_HUMAN |
|---|---|---|---|---|
| GO:0031323 | regulation of cellular metabolic process | 57.1429 | 4 | no |
| GO:0048522 | positive regulation of cellular process | 53.5714 | 4 | yes |
| GO:0006996 | organelle organization | 48.8095 | 4 | yes |
| GO:0008104 | protein localization | 46.4286 | 4 | yes |
| GO:0071705 | nitrogen compound transport | 41.6667 | 4 | yes |
| GO:0071702 | organic substance transport | 40.4762 | 4 | yes |
| GO:0051171 | regulation of nitrogen compound metabolic process | 40.4762 | 4 | no |
| GO:0060255 | regulation of macromolecule metabolic process | 40.4762 | 4 | no |
| GO:0080090 | regulation of primary metabolic process | 40.4762 | 4 | no |
| GO:0022607 | cellular component assembly | 39.2857 | 4 | no |
| GO:0048523 | negative regulation of cellular process | 39.2857 | 4 | no |
| GO:0015031 | protein transport | 38.0952 | 4 | yes |
| GO:0016192 | vesicle-mediated transport | 38.0952 | 4 | no |
| GO:0051128 | regulation of cellular component organization | 38.0952 | 4 | no |
| GO:0006886 | intracellular protein transport | 35.7143 | 4 | yes |
| GO:0009894 | regulation of catabolic process | 33.3333 | 4 | no |
| GO:0031329 | regulation of cellular catabolic process | 32.1429 | 5 | no |
| GO:0010646 | regulation of cell communication | 30.9524 | 4 | yes |
| GO:0009893 | positive regulation of metabolic process | 30.9524 | 4 | no |
| GO:0051246 | regulation of protein metabolic process | 28.5714 | 5 | no |
| GO:0009966 | regulation of signal transduction | 27.3810 | 4 | yes |
| GO:0010468 | regulation of gene expression | 27.3810 | 5 | no |
| GO:0010604 | positive regulation of macromolecule metabolic process | 27.3810 | 5 | no |
| GO:0031325 | positive regulation of cellular metabolic process | 27.3810 | 5 | no |
| GO:0051173 | positive regulation of nitrogen compound metabolic process | 26.1905 | 5 | no |
| GO:0051049 | regulation of transport | 26.1905 | 4 | no |
| GO:0009889 | regulation of biosynthetic process | 25.0000 | 4 | no |
| GO:0009892 | negative regulation of metabolic process | 25.0000 | 4 | no |
| GO:0033043 | regulation of organelle organization | 25.0000 | 5 | no |
| GO:0071310 | cellular response to organic substance | 25.0000 | 4 | no |
| GO:0010556 | regulation of macromolecule biosynthetic process | 23.8095 | 5 | no |
| GO:0032880 | regulation of protein localization | 23.8095 | 5 | no |
| GO:0060341 | regulation of cellular localization | 23.8095 | 4 | no |
| GO:0031326 | regulation of cellular biosynthetic process | 23.8095 | 5 | no |
| GO:0048584 | positive regulation of response to stimulus | 22.6190 | 4 | yes |
| GO:0010506 | regulation of autophagy | 22.6190 | 6 | no |
| GO:0044087 | regulation of cellular component biogenesis | 22.6190 | 4 | no |
| GO:0019219 | regulation of nucleobase-containing compound metabolic process | 21.4286 | 5 | no |
| GO:1902531 | regulation of intracellular signal transduction | 20.2381 | 5 | yes |
| GO:0051130 | positive regulation of cellular component organization | 20.2381 | 5 | no |
| GO:0051247 | positive regulation of protein metabolic process | 20.2381 | 6 | no |
| GO:0061024 | membrane organization | 19.0476 | 4 | yes |
| GO:0009967 | positive regulation of signal transduction | 17.8571 | 5 | yes |
| GO:0010647 | positive regulation of cell communication | 17.8571 | 5 | yes |
| GO:0023056 | positive regulation of signaling | 17.8571 | 4 | yes |
| GO:0016050 | vesicle organization | 15.4762 | 5 | yes |
| GO:0033365 | protein localization to organelle | 14.2857 | 5 | yes |
| GO:1902533 | positive regulation of intracellular signal transduction | 10.7143 | 6 | yes |
| GO:0035459 | vesicle cargo loading | 9.5238 | 4 | yes |
| GO:0006913 | nucleocytoplasmic transport | 8.3333 | 5 | yes |
| GO:0051169 | nuclear transport | 8.3333 | 4 | yes |
| GO:0072594 | establishment of protein localization to organelle | 8.3333 | 4 | yes |
| GO:0090110 | COPII-coated vesicle cargo loading | 8.3333 | 4 | yes |
| GO:0015931 | nucleobase-containing compound transport | 7.1429 | 5 | yes |
| GO:0050657 | nucleic acid transport | 7.1429 | 6 | yes |
| GO:0050658 | RNA transport | 7.1429 | 4 | yes |
| GO:0034504 | protein localization to nucleus | 5.9524 | 6 | yes |
| GO:0006606 | protein import into nucleus | 4.7619 | 5 | yes |
| GO:0032006 | regulation of TOR signaling | 4.7619 | 6 | yes |
| GO:0032008 | positive regulation of TOR signaling | 4.7619 | 7 | yes |
| GO:0051028 | mRNA transport | 4.7619 | 5 | yes |
| GO:0051170 | import into nucleus | 4.7619 | 6 | yes |
| GO:0006900 | vesicle budding from membrane | 3.5714 | 5 | yes |
| GO:0032527 | protein exit from endoplasmic reticulum | 3.5714 | 5 | yes |
| GO:0090114 | COPII-coated vesicle budding | 2.3810 | 6 | yes |
| GO:1903432 | regulation of TORC1 signaling | 2.3810 | 7 | yes |
| GO:1904263 | positive regulation of TORC1 signaling | 2.3810 | 8 | yes |
Disease
| Term | Name | % | Distance from top the of the tree | Annotated in SEC13_HUMAN |
|---|---|---|---|---|
| DOID:1289 | neurodegenerative disease | 3.5714 | 4 | no |
| DOID:231 | motor neuron disease | 3.5714 | 5 | no |
| DOID:331 | central nervous system disease | 3.5714 | 3 | no |
| DOID:114 | heart disease | 3.5714 | 3 | no |
| DOID:0111198 | autosomal dominant distal hereditary motor neuronopathy | 2.3810 | 7 | no |
| DOID:12377 | spinal muscular atrophy | 2.3810 | 6 | no |
| DOID:332 | amyotrophic lateral sclerosis | 2.3810 | 6 | no |
| DOID:0050539 | Charcot-Marie-Tooth disease type 2 | 2.3810 | 7 | no |
| DOID:10595 | Charcot-Marie-Tooth disease | 2.3810 | 6 | no |
| DOID:440 | neuromuscular disease | 2.3810 | 5 | no |
| DOID:574 | peripheral nervous system disease | 2.3810 | 3 | no |
| DOID:870 | neuropathy | 2.3810 | 4 | no |
| DOID:0050700 | cardiomyopathy | 2.3810 | 4 | no |
| DOID:0060036 | intrinsic cardiomyopathy | 2.3810 | 5 | no |
| DOID:0080000 | muscular disease | 2.3810 | 3 | no |
| DOID:12930 | dilated cardiomyopathy | 2.3810 | 6 | no |
| DOID:423 | myopathy | 2.3810 | 5 | no |
| DOID:66 | muscle tissue disease | 2.3810 | 4 | no |
| DOID:65 | connective tissue disease | 2.3810 | 3 | no |
All partners
| Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
|---|---|---|---|---|
| SC16A_HUMAN | [view interactions] | Low throughput | no | yes |
| NU107_HUMAN | [view interactions] | Low throughput | no | no |
| SEH1_HUMAN | [view interactions] | Low throughput | no | no |
| NUP85_HUMAN | [view interactions] | Low throughput | no | yes |
| SC31A_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| SEC13_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| NUP62_HUMAN | [view interactions] | Low throughput | no | yes |
| SC23A_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| ELYS_HUMAN | [view interactions] | Low throughput | no | yes |
| RB11A_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| STAM2_HUMAN | [view interactions] | Low throughput | no | yes |
| STAM1_HUMAN | [view interactions] | Low throughput | no | yes |
| FLNB_HUMAN | [view interactions] | High throughput | no | no |
| PNCB_HUMAN | [view interactions] | High throughput | no | no |
| SYSC_HUMAN | [view interactions] | High throughput | no | yes |
| SPS1_HUMAN | [view interactions] | High throughput | no | yes |
| CLAP2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| DCTN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DYLT3_HUMAN | [view interactions] | High throughput | no | yes |
| EF1A1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ZN276_HUMAN | [view interactions] | High throughput | no | yes |
| CKAP5_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CLAP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DYL1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RAGP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TPR_HUMAN | [view interactions] | High throughput | no | yes |
| CENPH_HUMAN | [view interactions] | High throughput | no | yes |
| MD1L1_HUMAN | [view interactions] | High throughput | no | yes |
| AAAS_HUMAN | [view interactions] | High throughput | no | yes |
| CENPE_HUMAN | [view interactions] | High throughput | no | no |
| CENPI_HUMAN | [view interactions] | High throughput | no | no |
| EAF6_HUMAN | [view interactions] | High throughput | no | no |
| SGO1_HUMAN | [view interactions] | High throughput | no | no |
| SPAG5_HUMAN | [view interactions] | High throughput | no | yes |
| TPC12_HUMAN | [view interactions] | High throughput | no | yes |
| ZW10_HUMAN | [view interactions] | High throughput | no | yes |
| ZN207_HUMAN | [view interactions] | High throughput | no | yes |
| EWS_HUMAN | [view interactions] | High throughput | no | yes |
| TERA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CNOT9_HUMAN | [view interactions] | High throughput | no | yes |
| PTN1_HUMAN | [view interactions] | High throughput | no | yes |
| S2546_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CXD3_HUMAN | [view interactions] | High throughput | no | no |
| RAD52_HUMAN | [view interactions] | High throughput | no | no |
| FTM_HUMAN | [view interactions] | High throughput | no | yes |
| NANOG_HUMAN | [view interactions] | High throughput | no | no |
| NANP8_HUMAN | [view interactions] | High throughput | no | no |
| NUP98_HUMAN | [view interactions] | High throughput | no | no |
| RBP2_HUMAN | [view interactions] | High throughput | no | yes |
| GORS1_HUMAN | [view interactions] | High throughput | no | yes |
| RBM8A_HUMAN | [view interactions] | High throughput | no | yes |
| AP1S2_HUMAN | [view interactions] | High throughput | no | no |
| FLNA_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| UBC9_HUMAN | [view interactions] | High throughput | no | yes |
| SC24C_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CLCB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GTSE1_HUMAN | [view interactions] | High throughput | no | no |
| PICAL_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CLH1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SESN2_HUMAN | [view interactions] | High throughput | no | no |
| USO1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GAK_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MIO_HUMAN | [view interactions] | High throughput | no | yes |
| YJU2_HUMAN | [view interactions] | High throughput | no | yes |
| WDR24_HUMAN | [view interactions] | High throughput | no | yes |
| SPDLY_HUMAN | [view interactions] | High throughput | no | yes |
| FWCH2_HUMAN | [view interactions] | High throughput | no | no |
| PPWD1_HUMAN | [view interactions] | High throughput | no | yes |
| NU133_HUMAN | [view interactions] | High throughput | no | yes |
| NUP37_HUMAN | [view interactions] | High throughput | no | yes |
| PR38A_HUMAN | [view interactions] | High throughput | no | no |
| NU160_HUMAN | [view interactions] | High throughput | no | no |
| ACY1_HUMAN | [view interactions] | High throughput | no | no |
| BCR_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ZBTB5_HUMAN | [view interactions] | High throughput | no | yes |
| WDR59_HUMAN | [view interactions] | High throughput | no | yes |
| TFG_HUMAN | [view interactions] | High throughput | no | yes |
| NUP43_HUMAN | [view interactions] | High throughput | no | yes |
| OCRL_HUMAN | [view interactions] | High throughput | no | yes |
| SZT2_HUMAN | [view interactions] | High throughput | no | yes |
| DICER_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MECOM_HUMAN | [view interactions] | High throughput | no | yes |
| HD_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DOCK3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CUL4A_HUMAN | [view interactions] | High throughput | no | no |
| PKHM1_HUMAN | [view interactions] | High throughput | no | yes |
| 1433F_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CFTR_HUMAN | [view interactions] | High throughput | no | no |
| HMGA2_HUMAN | [view interactions] | High throughput | no | yes |
| XPO1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| BET1_HUMAN | [view interactions] | High throughput | no | no |
| CDK8_HUMAN | [view interactions] | High throughput | no | no |
| EEA1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LMNA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TGON2_HUMAN | [view interactions] | High throughput | no | yes |
| SNF5_HUMAN | [view interactions] | High throughput | no | yes |
| ST38L_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TEC_HUMAN | [view interactions] | High throughput | no | yes |
| KC1D_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KC1A_HUMAN | [view interactions] | High throughput | no | yes |
| KC1E_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AURKB_HUMAN | [view interactions] | High throughput | no | yes |
| SCYL1_HUMAN | [view interactions] | High throughput | no | yes |
| ELF4_HUMAN | [view interactions] | High throughput | no | no |
| GATA4_HUMAN | [view interactions] | High throughput | no | no |
| KLF16_HUMAN | [view interactions] | High throughput | no | yes |
| KLF8_HUMAN | [view interactions] | High throughput | no | no |
| SOX5_HUMAN | [view interactions] | High throughput | no | no |
| CRCM_HUMAN | [view interactions] | High throughput | no | no |
| ARF6_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| IF6_HUMAN | [view interactions] | High throughput | no | yes |
| CCNA1_HUMAN | [view interactions] | High throughput | no | no |
| HLAB_HUMAN | [view interactions] | High throughput | no | yes |
| EGFR_HUMAN | [view interactions] | High throughput | no | no |
| PKHA7_HUMAN | [view interactions] | High throughput | no | yes |
| LITD1_HUMAN | [view interactions] | High throughput | no | no |
| HDAC4_HUMAN | [view interactions] | High throughput | no | yes |
| CLD12_HUMAN | [view interactions] | High throughput | no | yes |
| TRAF5_HUMAN | [view interactions] | High throughput | no | yes |
| NUP42_HUMAN | [view interactions] | High throughput | no | no |
| P121A_HUMAN | [view interactions] | High throughput | no | yes |
| SC16B_HUMAN | [view interactions] | High throughput | no | no |
| LT4R2_HUMAN | [view interactions] | High throughput | no | no |
| TAB2_HUMAN | [view interactions] | High throughput | no | yes |
| CUL3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ESR2_HUMAN | [view interactions] | High throughput | no | no |
| ESR1_HUMAN | [view interactions] | High throughput | no | no |
| HSPB1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| B9D2_HUMAN | [view interactions] | High throughput | no | yes |
| DYRK2_HUMAN | [view interactions] | High throughput | no | yes |
| ETV6_HUMAN | [view interactions] | High throughput | no | no |
| EPHA8_HUMAN | [view interactions] | High throughput | no | no |
| AGRF5_HUMAN | [view interactions] | High throughput | no | no |
| HPLN2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CFA43_HUMAN | [view interactions] | High throughput | no | no |
| SIR7_HUMAN | [view interactions] | High throughput | no | yes |
| FOXP3_HUMAN | [view interactions] | High throughput | no | no |
| BAG3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| MK09_HUMAN | [view interactions] | High throughput | no | yes |
| FUS_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RING2_HUMAN | [view interactions] | High throughput | no | yes |
| STX7_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MED4_HUMAN | [view interactions] | High throughput | no | yes |
| QRIC1_HUMAN | [view interactions] | High throughput | no | yes |
| IF16_HUMAN | [view interactions] | High throughput | no | no |
| MCM2_HUMAN | [view interactions] | High throughput | no | no |
| KSR1_HUMAN | [view interactions] | High throughput | no | yes |
| NKX21_HUMAN | [view interactions] | High throughput | no | no |
| WDTC1_HUMAN | [view interactions] | High throughput | no | yes |
| DAA10_HUMAN | [view interactions] | High throughput | no | yes |
| EDEM3_HUMAN | [view interactions] | High throughput | no | yes |
| BRCA1_HUMAN | [view interactions] | High throughput | no | yes |
| KLH12_HUMAN | [view interactions] | High throughput | no | no |
| PDCD6_HUMAN | [view interactions] | High throughput | no | no |
| CTNB1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RASK_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RMD5A_HUMAN | [view interactions] | High throughput | no | yes |
| PIHD1_HUMAN | [view interactions] | High throughput | no | yes |
| LAMP1_HUMAN | [view interactions] | High throughput | no | yes |
| TNIP2_HUMAN | [view interactions] | High throughput | no | yes |
| ARI1_HUMAN | [view interactions] | High throughput | no | yes |
| HEXI1_HUMAN | [view interactions] | High throughput | no | yes |
| RECQ4_HUMAN | [view interactions] | High throughput | no | yes |
| P53_HUMAN | [view interactions] | High throughput | no | no |
| A16L1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FAF1_HUMAN | [view interactions] | High throughput | no | yes |
| SC23B_HUMAN | [view interactions] | High throughput | no | yes |
| SC24A_HUMAN | [view interactions] | High throughput | no | no |
| SC24B_HUMAN | [view interactions] | High throughput | no | yes |
| SC24D_HUMAN | [view interactions] | High throughput | no | yes |
| HDAC2_HUMAN | [view interactions] | High throughput | no | yes |
| NHLC2_HUMAN | [view interactions] | High throughput | no | yes |
| TIP_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CYLD_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PP1A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CUL7_HUMAN | [view interactions] | High throughput | no | yes |
| PKHA4_HUMAN | [view interactions] | High throughput | no | yes |
| EMC4_HUMAN | [view interactions] | High throughput | no | yes |
| ECT2_HUMAN | [view interactions] | High throughput | no | no |
| KI20A_HUMAN | [view interactions] | High throughput | no | yes |
| NMRL1_HUMAN | [view interactions] | High throughput | no | yes |
| AKT3_HUMAN | [view interactions] | High throughput | no | yes |
| NUPR1_HUMAN | [view interactions] | High throughput | no | no |
| CIC_HUMAN | [view interactions] | High throughput | no | yes |
| ANDR_HUMAN | [view interactions] | High throughput | no | no |
| SKA3_HUMAN | [view interactions] | High throughput | no | no |
| WDR5_HUMAN | [view interactions] | High throughput | no | no |
| FA83H_HUMAN | [view interactions] | High throughput | no | yes |
| RHG18_HUMAN | [view interactions] | High throughput | no | yes |
| CLCA_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ROA2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TCPE_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TPC1_HUMAN | [view interactions] | High throughput | no | yes |
| GRWD1_HUMAN | [view interactions] | High throughput | no | no |
| PGTA_HUMAN | [view interactions] | High throughput | no | yes |
| MCFD2_HUMAN | [view interactions] | High throughput | no | yes |
| NRBF2_HUMAN | [view interactions] | High throughput | no | yes |
| S23IP_HUMAN | [view interactions] | High throughput | no | yes |
| SAR1A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RAB14_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RIT1_HUMAN | [view interactions] | High throughput | no | yes |
| S12A2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RPAB1_HUMAN | [view interactions] | High throughput | no | yes |
| PRP19_HUMAN | [view interactions] | High throughput | no | yes |
| PSB1_HUMAN | [view interactions] | High throughput | no | yes |
| AHSA1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CPSF3_HUMAN | [view interactions] | Computational | no | yes |
| VA0E1_HUMAN | [view interactions] | Computational | no | no |
| RRAGD_HUMAN | [view interactions] | Computational | no | yes |
| SAR1B_HUMAN | [view interactions] | Computational | no | yes |
| ANR40_HUMAN | [view interactions] | Computational | no | yes |
| RRAGC_HUMAN | [view interactions] | Computational | no | yes |
| TPC2A_HUMAN | [view interactions] | Computational | no | yes |
| TPC2B_HUMAN | [view interactions] | Computational | no | no |
| NU155_HUMAN | [view interactions] | Computational | no | yes |
| HNRPC_HUMAN | [view interactions] | Computational | no | yes |
| RSMB_HUMAN | [view interactions] | Computational | no | yes |
| BIP_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| LST8_HUMAN | [view interactions] | Computational | no | yes |
| VATC1_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| VATE2_HUMAN | [view entry] [view interactions] | Computational | yes | no |
| LTOR1_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| VATB2_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| CPSF4_HUMAN | [view interactions] | Computational | no | yes |
| CPSF1_HUMAN | [view interactions] | Computational | no | no |
| HS71B_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| HS71A_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| HS74L_HUMAN | [view entry] [view interactions] | Computational | yes | no |
| GLE1_HUMAN | [view interactions] | Computational | no | yes |
| BUB3_HUMAN | [view interactions] | Computational | no | yes |
| NEK7_HUMAN | [view interactions] | Computational | no | yes |
| RRAGB_HUMAN | [view interactions] | Computational | no | yes |
| SC22A_HUMAN | [view interactions] | Computational | no | no |
| GOSR2_HUMAN | [view interactions] | Computational | no | yes |
| PREB_HUMAN | [view interactions] | Computational | no | yes |
| SC22B_HUMAN | [view entry] [view interactions] | Computational | yes | no |
| NU205_HUMAN | [view interactions] | Computational | no | no |
| HSP13_HUMAN | [view interactions] | Computational | no | yes |
| PO210_HUMAN | [view interactions] | Computational | no | yes |
| HSP72_HUMAN | [view entry] [view interactions] | Computational | yes | no |
| RAB1B_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| NUP54_HUMAN | [view interactions] | Computational | no | yes |
| LTOR3_HUMAN | [view interactions] | Computational | no | yes |
| LTOR2_HUMAN | [view interactions] | Computational | no | yes |
| VATF_HUMAN | [view interactions] | Computational | no | yes |
| IF4E_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| CDK1_HUMAN | [view interactions] | Computational | no | no |
| GRP75_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| NEK6_HUMAN | [view interactions] | Computational | no | yes |
| NUP88_HUMAN | [view interactions] | Computational | no | yes |
| RUXF_HUMAN | [view interactions] | Computational | no | no |
| RHEB_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| TPPC1_HUMAN | [view interactions] | Computational | no | yes |
| DDX20_HUMAN | [view interactions] | Computational | no | no |
| NU214_HUMAN | [view interactions] | Computational | no | no |
| HIKES_HUMAN | [view interactions] | Computational | no | yes |
| GEMI6_HUMAN | [view interactions] | Computational | no | yes |
| RRAGA_HUMAN | [view interactions] | Computational | no | yes |
| HS12A_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| VATA_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| IPO8_HUMAN | [view interactions] | Computational | no | no |
| SPN1_HUMAN | [view interactions] | Computational | no | yes |
| TMEDA_HUMAN | [view interactions] | Computational | no | yes |
| TMED2_HUMAN | [view interactions] | Computational | no | yes |
| RAE1L_HUMAN | [view interactions] | Computational | no | no |
| SUMO1_HUMAN | [view interactions] | Computational | no | yes |
| COPE_HUMAN | [view interactions] | Computational | no | yes |
| YKT6_HUMAN | [view interactions] | Computational | no | yes |
| WDR33_HUMAN | [view interactions] | Computational | no | yes |
| GEMI2_HUMAN | [view interactions] | Computational | no | yes |
| VPP3_HUMAN | [view interactions] | Computational | no | no |
| HSP7C_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| NUP93_HUMAN | [view interactions] | Computational | no | yes |
| NUP50_HUMAN | [view interactions] | Computational | no | yes |
| CAST1_HUMAN | [view interactions] | Computational | no | yes |
| CCNB2_HUMAN | [view interactions] | Computational | no | yes |
| VATE1_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| RAB1A_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| GEMI4_HUMAN | [view interactions] | Computational | no | yes |
| SP100_HUMAN | [view interactions] | Computational | no | no |
| VATG2_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| SLBP_HUMAN | [view interactions] | Computational | no | yes |
| SYMPK_HUMAN | [view interactions] | Computational | no | yes |
| NUP35_HUMAN | [view interactions] | Computational | no | yes |
| SC31B_HUMAN | [view interactions] | Computational | no | yes |
| HSP7E_HUMAN | [view interactions] | Computational | no | yes |
| VA0D2_HUMAN | [view interactions] | Computational | no | no |
| SUMO3_HUMAN | [view interactions] | Computational | no | yes |
| SCFD1_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| HSP76_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| VATD_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| NEK9_HUMAN | [view interactions] | Computational | no | yes |
| RPTOR_HUMAN | [view interactions] | Computational | no | yes |
| NU188_HUMAN | [view interactions] | Computational | no | yes |
| HSP74_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| SMD2_HUMAN | [view interactions] | Computational | no | yes |
| FIP1_HUMAN | [view interactions] | Computational | no | yes |
| GEMI8_HUMAN | [view interactions] | Computational | no | yes |
| FLCN_HUMAN | [view interactions] | Computational | no | yes |
| VATG1_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| PHAX_HUMAN | [view interactions] | Computational | no | yes |
| VATG3_HUMAN | [view interactions] | Computational | no | no |
| RUXE_HUMAN | [view interactions] | Computational | no | no |
| TOP2A_HUMAN | [view interactions] | Computational | no | no |
| NU153_HUMAN | [view interactions] | Computational | no | yes |
| PEF1_HUMAN | [view interactions] | Computational | no | no |
| GEMI5_HUMAN | [view interactions] | Computational | no | yes |
| MDM2_HUMAN | [view interactions] | Computational | no | yes |
| STX5_HUMAN | [view interactions] | Computational | no | yes |
| COPB2_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| VATL_HUMAN | [view interactions] | Computational | no | no |
| AGO2_HUMAN | [view interactions] | Computational | no | yes |
| VA0D1_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| LTOR4_HUMAN | [view interactions] | Computational | no | yes |
| NPRL2_HUMAN | [view interactions] | Computational | no | yes |
| SMD1_HUMAN | [view interactions] | Computational | no | yes |
| CPSF2_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| HS12B_HUMAN | [view interactions] | Computational | no | yes |
| VATB1_HUMAN | [view interactions] | Computational | no | no |
| SUMO2_HUMAN | [view interactions] | Computational | no | yes |
| VATH_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| HXK4_HUMAN | [view interactions] | Computational | no | yes |
| NUP58_HUMAN | [view interactions] | Computational | no | yes |
| NCOA5_HUMAN | [view interactions] | Computational | no | yes |
| MTOR_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| VA0E2_HUMAN | [view interactions] | Computational | no | no |
| CCNB1_HUMAN | [view interactions] | Computational | no | no |
| LMAN1_HUMAN | [view interactions] | Computational | no | yes |
| HS71L_HUMAN | [view entry] [view interactions] | Computational | yes | no |
| RUXG_HUMAN | [view interactions] | Computational | no | yes |
| PML_HUMAN | [view interactions] | Computational | no | yes |
| GEMI7_HUMAN | [view interactions] | Computational | no | no |
| TMED7_HUMAN | [view interactions] | Computational | no | yes |
| SMD3_HUMAN | [view interactions] | Computational | no | yes |
| VATC2_HUMAN | [view interactions] | Computational | no | yes |
| RAN_HUMAN | [view entry] [view interactions] | Computational | yes | no |
| XPOT_HUMAN | [view interactions] | Computational | no | no |