DICER_HUMAN
Evidence for PS localization
Functions
Double-stranded RNA (dsRNA) endoribonuclease playing a central role in short dsRNA-mediated post-transcriptional gene silencing. Cleaves naturally occurring long dsRNAs and short hairpin pre-microRNAs (miRNA) into fragments of twenty-one to twenty-three nucleotides with 3 overhang of two nucleotides, producing respectively short interfering RNAs (siRNA) and mature microRNAs. SiRNAs and miRNAs serve as guide to direct the RNA-induced silencing complex (RISC) to complementary RNAs to degrade them or prevent their translation. Gene silencing mediated by siRNAs, also called RNA interference, controls the elimination of transcripts from mobile and repetitive DNA elements of the genome but also the degradation of exogenous RNA of viral origin for instance. The miRNA pathway on the other side is a mean to specifically regulate the expression of target genes. [View more on UniProt]
Protein features
Binary interactions with known binding regions
To display all evidence describing the interaction with a partner, click on the protein name left to the bars.
Network
Isoforms
Disease-causing germline mutations
No data found.
Linear motifs
No annotated instance was found. To search for linear motifs, use the ELM prediction server.
Fingerprint
Molecular function
| Term | Name | % | Distance from the top of the tree | Annotated in DICER_HUMAN |
|---|---|---|---|---|
| GO:0003723 | RNA binding | 80.5195 | 4 | yes |
| GO:0003729 | mRNA binding | 29.8701 | 5 | no |
| GO:0017076 | purine nucleotide binding | 23.3766 | 4 | yes |
| GO:0032555 | purine ribonucleotide binding | 23.3766 | 4 | yes |
| GO:0035639 | purine ribonucleoside triphosphate binding | 23.3766 | 4 | yes |
| GO:0003677 | DNA binding | 20.7792 | 4 | yes |
| GO:0005524 | ATP binding | 20.7792 | 5 | yes |
| GO:0030554 | adenyl nucleotide binding | 20.7792 | 5 | yes |
| GO:0032559 | adenyl ribonucleotide binding | 20.7792 | 5 | yes |
| GO:0046872 | metal ion binding | 16.8831 | 4 | yes |
| GO:0003725 | double-stranded RNA binding | 14.2857 | 5 | yes |
| GO:0004518 | nuclease activity | 7.7922 | 4 | yes |
| GO:0004519 | endonuclease activity | 6.4935 | 5 | yes |
| GO:0061980 | regulatory RNA binding | 6.4935 | 5 | yes |
| GO:0004521 | endoribonuclease activity | 5.1948 | 5 | yes |
| GO:0004540 | ribonuclease activity | 5.1948 | 4 | yes |
| GO:0016891 | endoribonuclease activity, producing 5-phosphomonoesters | 5.1948 | 6 | yes |
| GO:0016893 | endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5-phosphomonoesters | 5.1948 | 6 | yes |
| GO:0004520 | endodeoxyribonuclease activity | 3.8961 | 5 | yes |
| GO:0004525 | ribonuclease III activity | 3.8961 | 6 | yes |
| GO:0004536 | deoxyribonuclease activity | 3.8961 | 4 | yes |
| GO:0032296 | double-stranded RNA-specific ribonuclease activity | 3.8961 | 5 | yes |
| GO:0035197 | siRNA binding | 3.8961 | 6 | yes |
| GO:0070883 | pre-miRNA binding | 3.8961 | 5 | yes |
| GO:0004530 | deoxyribonuclease I activity | 2.5974 | 7 | yes |
| GO:0016888 | endodeoxyribonuclease activity, producing 5-phosphomonoesters | 2.5974 | 6 | yes |
Biological process
| Term | Name | % | Distance from top the of the tree | Annotated in DICER_HUMAN |
|---|---|---|---|---|
| GO:0080090 | regulation of primary metabolic process | 66.2338 | 4 | yes |
| GO:0031323 | regulation of cellular metabolic process | 64.9351 | 4 | yes |
| GO:0051171 | regulation of nitrogen compound metabolic process | 64.9351 | 4 | yes |
| GO:0060255 | regulation of macromolecule metabolic process | 62.3377 | 4 | yes |
| GO:0010468 | regulation of gene expression | 57.1429 | 5 | yes |
| GO:0048522 | positive regulation of cellular process | 57.1429 | 4 | yes |
| GO:0048523 | negative regulation of cellular process | 55.8442 | 4 | yes |
| GO:0009889 | regulation of biosynthetic process | 48.0519 | 4 | yes |
| GO:0031326 | regulation of cellular biosynthetic process | 48.0519 | 5 | yes |
| GO:0009893 | positive regulation of metabolic process | 48.0519 | 4 | no |
| GO:0009892 | negative regulation of metabolic process | 46.7532 | 4 | yes |
| GO:0010556 | regulation of macromolecule biosynthetic process | 46.7532 | 5 | yes |
| GO:0010604 | positive regulation of macromolecule metabolic process | 45.4545 | 5 | no |
| GO:0010605 | negative regulation of macromolecule metabolic process | 44.1558 | 5 | yes |
| GO:0031324 | negative regulation of cellular metabolic process | 42.8571 | 5 | yes |
| GO:0019219 | regulation of nucleobase-containing compound metabolic process | 41.5584 | 5 | yes |
| GO:0051172 | negative regulation of nitrogen compound metabolic process | 41.5584 | 5 | yes |
| GO:0051173 | positive regulation of nitrogen compound metabolic process | 41.5584 | 5 | no |
| GO:0051252 | regulation of RNA metabolic process | 40.2597 | 5 | yes |
| GO:0090304 | nucleic acid metabolic process | 40.2597 | 4 | yes |
| GO:0051246 | regulation of protein metabolic process | 40.2597 | 5 | no |
| GO:0031325 | positive regulation of cellular metabolic process | 37.6623 | 5 | no |
| GO:0016070 | RNA metabolic process | 36.3636 | 5 | yes |
| GO:0006396 | RNA processing | 33.7662 | 6 | yes |
| GO:0009059 | macromolecule biosynthetic process | 33.7662 | 4 | no |
| GO:0044271 | cellular nitrogen compound biosynthetic process | 33.7662 | 4 | no |
| GO:0010608 | post-transcriptional regulation of gene expression | 32.4675 | 6 | yes |
| GO:0022607 | cellular component assembly | 31.1688 | 4 | yes |
| GO:1901566 | organonitrogen compound biosynthetic process | 31.1688 | 4 | no |
| GO:0051128 | regulation of cellular component organization | 31.1688 | 4 | no |
| GO:0010646 | regulation of cell communication | 29.8701 | 4 | no |
| GO:0006412 | translation | 29.8701 | 4 | no |
| GO:0006518 | peptide metabolic process | 29.8701 | 4 | no |
| GO:0034645 | cellular macromolecule biosynthetic process | 29.8701 | 4 | no |
| GO:0043043 | peptide biosynthetic process | 29.8701 | 5 | no |
| GO:0043603 | cellular amide metabolic process | 29.8701 | 4 | no |
| GO:0043604 | amide biosynthetic process | 29.8701 | 5 | no |
| GO:0010629 | negative regulation of gene expression | 28.5714 | 6 | yes |
| GO:0010628 | positive regulation of gene expression | 28.5714 | 6 | no |
| GO:0009890 | negative regulation of biosynthetic process | 27.2727 | 5 | yes |
| GO:0010558 | negative regulation of macromolecule biosynthetic process | 27.2727 | 6 | yes |
| GO:0031327 | negative regulation of cellular biosynthetic process | 27.2727 | 6 | yes |
| GO:0034248 | regulation of cellular amide metabolic process | 27.2727 | 5 | no |
| GO:0006355 | regulation of DNA-templated transcription | 25.9740 | 6 | yes |
| GO:0043933 | protein-containing complex organization | 25.9740 | 4 | yes |
| GO:1903506 | regulation of nucleic acid-templated transcription | 25.9740 | 7 | yes |
| GO:2001141 | regulation of RNA biosynthetic process | 25.9740 | 6 | yes |
| GO:0071702 | organic substance transport | 25.9740 | 4 | no |
| GO:0071705 | nitrogen compound transport | 25.9740 | 4 | no |
| GO:0002181 | cytoplasmic translation | 25.9740 | 5 | no |
| GO:0006417 | regulation of translation | 25.9740 | 6 | no |
| GO:2000112 | regulation of cellular macromolecule biosynthetic process | 25.9740 | 6 | no |
| GO:0051247 | positive regulation of protein metabolic process | 25.9740 | 6 | no |
| GO:0065003 | protein-containing complex assembly | 24.6753 | 5 | yes |
| GO:0051248 | negative regulation of protein metabolic process | 24.6753 | 6 | no |
| GO:0009891 | positive regulation of biosynthetic process | 24.6753 | 5 | no |
| GO:0031328 | positive regulation of cellular biosynthetic process | 24.6753 | 6 | no |
| GO:0006996 | organelle organization | 24.6753 | 4 | no |
| GO:0009966 | regulation of signal transduction | 24.6753 | 4 | no |
| GO:0009894 | regulation of catabolic process | 23.3766 | 4 | no |
| GO:0010557 | positive regulation of macromolecule biosynthetic process | 23.3766 | 6 | no |
| GO:0045934 | negative regulation of nucleobase-containing compound metabolic process | 22.0779 | 6 | yes |
| GO:0031329 | regulation of cellular catabolic process | 22.0779 | 5 | no |
| GO:1903311 | regulation of mRNA metabolic process | 22.0779 | 6 | no |
| GO:0045935 | positive regulation of nucleobase-containing compound metabolic process | 22.0779 | 6 | no |
| GO:1902531 | regulation of intracellular signal transduction | 22.0779 | 5 | no |
| GO:0010941 | regulation of cell death | 20.7792 | 4 | no |
| GO:0048584 | positive regulation of response to stimulus | 20.7792 | 4 | no |
| GO:0006357 | regulation of transcription by RNA polymerase II | 19.4805 | 7 | yes |
| GO:0034660 | ncRNA metabolic process | 19.4805 | 6 | yes |
| GO:0045595 | regulation of cell differentiation | 19.4805 | 4 | yes |
| GO:0051253 | negative regulation of RNA metabolic process | 19.4805 | 6 | yes |
| GO:0034470 | ncRNA processing | 18.1818 | 7 | yes |
| GO:0042127 | regulation of cell population proliferation | 18.1818 | 4 | yes |
| GO:0009057 | macromolecule catabolic process | 14.2857 | 4 | yes |
| GO:0022618 | ribonucleoprotein complex assembly | 12.9870 | 6 | yes |
| GO:0044265 | cellular macromolecule catabolic process | 12.9870 | 4 | yes |
| GO:0071826 | ribonucleoprotein complex subunit organization | 12.9870 | 5 | yes |
| GO:0051240 | positive regulation of multicellular organismal process | 11.6883 | 4 | yes |
| GO:0006259 | DNA metabolic process | 10.3896 | 4 | yes |
| GO:0006401 | RNA catabolic process | 10.3896 | 5 | yes |
| GO:0008285 | negative regulation of cell population proliferation | 10.3896 | 5 | yes |
| GO:0019439 | aromatic compound catabolic process | 10.3896 | 4 | yes |
| GO:0034655 | nucleobase-containing compound catabolic process | 10.3896 | 4 | yes |
| GO:0044270 | cellular nitrogen compound catabolic process | 10.3896 | 4 | yes |
| GO:0045892 | negative regulation of DNA-templated transcription | 10.3896 | 7 | yes |
| GO:0046700 | heterocycle catabolic process | 10.3896 | 4 | yes |
| GO:1901361 | organic cyclic compound catabolic process | 10.3896 | 4 | yes |
| GO:1902679 | negative regulation of RNA biosynthetic process | 10.3896 | 7 | yes |
| GO:1903507 | negative regulation of nucleic acid-templated transcription | 10.3896 | 8 | yes |
| GO:0000122 | negative regulation of transcription by RNA polymerase II | 9.0909 | 8 | yes |
| GO:0001817 | regulation of cytokine production | 9.0909 | 4 | yes |
| GO:0035196 | miRNA processing | 9.0909 | 9 | yes |
| GO:0045596 | negative regulation of cell differentiation | 9.0909 | 5 | yes |
| GO:0051093 | negative regulation of developmental process | 9.0909 | 4 | yes |
| GO:0051094 | positive regulation of developmental process | 9.0909 | 4 | yes |
| GO:0070918 | small regulatory ncRNA processing | 9.0909 | 8 | yes |
| GO:2000026 | regulation of multicellular organismal development | 9.0909 | 4 | yes |
| GO:0045597 | positive regulation of cell differentiation | 7.7922 | 5 | yes |
| GO:0006399 | tRNA metabolic process | 6.4935 | 7 | yes |
| GO:0010586 | miRNA metabolic process | 6.4935 | 7 | yes |
| GO:0030030 | cell projection organization | 6.4935 | 4 | yes |
| GO:0031054 | pre-miRNA processing | 6.4935 | 10 | yes |
| GO:0051241 | negative regulation of multicellular organismal process | 6.4935 | 4 | yes |
| GO:0051960 | regulation of nervous system development | 6.4935 | 5 | yes |
| GO:0060284 | regulation of cell development | 6.4935 | 5 | yes |
| GO:0010720 | positive regulation of cell development | 5.1948 | 6 | yes |
| GO:0031644 | regulation of nervous system process | 5.1948 | 5 | yes |
| GO:0044057 | regulation of system process | 5.1948 | 4 | yes |
| GO:0050767 | regulation of neurogenesis | 5.1948 | 6 | yes |
| GO:0070922 | RISC complex assembly | 5.1948 | 7 | yes |
| GO:0001818 | negative regulation of cytokine production | 3.8961 | 5 | yes |
| GO:0010721 | negative regulation of cell development | 3.8961 | 6 | yes |
| GO:0014013 | regulation of gliogenesis | 3.8961 | 7 | yes |
| GO:0014014 | negative regulation of gliogenesis | 3.8961 | 7 | yes |
| GO:0030422 | siRNA processing | 3.8961 | 9 | yes |
| GO:0031641 | regulation of myelination | 3.8961 | 4 | yes |
| GO:0031643 | positive regulation of myelination | 3.8961 | 5 | yes |
| GO:0031646 | positive regulation of nervous system process | 3.8961 | 5 | yes |
| GO:0034661 | ncRNA catabolic process | 3.8961 | 6 | yes |
| GO:0045685 | regulation of glial cell differentiation | 3.8961 | 5 | yes |
| GO:0050768 | negative regulation of neurogenesis | 3.8961 | 6 | yes |
| GO:0050769 | positive regulation of neurogenesis | 3.8961 | 6 | yes |
| GO:0051961 | negative regulation of nervous system development | 3.8961 | 5 | yes |
| GO:0051962 | positive regulation of nervous system development | 3.8961 | 5 | yes |
| GO:0090305 | nucleic acid phosphodiester bond hydrolysis | 3.8961 | 5 | yes |
| GO:0000737 | DNA catabolic process, endonucleolytic | 2.5974 | 6 | yes |
| GO:0006308 | DNA catabolic process | 2.5974 | 5 | yes |
| GO:0006309 | apoptotic DNA fragmentation | 2.5974 | 7 | yes |
| GO:0010624 | regulation of Schwann cell proliferation | 2.5974 | 6 | yes |
| GO:0010626 | negative regulation of Schwann cell proliferation | 2.5974 | 7 | yes |
| GO:0014015 | positive regulation of gliogenesis | 2.5974 | 7 | yes |
| GO:0014038 | regulation of Schwann cell differentiation | 2.5974 | 6 | yes |
| GO:0014040 | positive regulation of Schwann cell differentiation | 2.5974 | 7 | yes |
| GO:0016078 | tRNA catabolic process | 2.5974 | 7 | yes |
| GO:0016441 | post-transcriptional gene silencing | 2.5974 | 7 | yes |
| GO:0032288 | myelin assembly | 2.5974 | 4 | yes |
| GO:0032290 | peripheral nervous system myelin formation | 2.5974 | 5 | yes |
| GO:0032680 | regulation of tumor necrosis factor production | 2.5974 | 6 | yes |
| GO:0032720 | negative regulation of tumor necrosis factor production | 2.5974 | 7 | yes |
| GO:0032990 | cell part morphogenesis | 2.5974 | 4 | yes |
| GO:0038061 | NIK/NF-kappaB signaling | 2.5974 | 4 | yes |
| GO:0045687 | positive regulation of glial cell differentiation | 2.5974 | 6 | yes |
| GO:0048812 | neuron projection morphogenesis | 2.5974 | 7 | yes |
| GO:0048858 | cell projection morphogenesis | 2.5974 | 5 | yes |
| GO:0060251 | regulation of glial cell proliferation | 2.5974 | 5 | yes |
| GO:0060253 | negative regulation of glial cell proliferation | 2.5974 | 6 | yes |
| GO:0090501 | RNA phosphodiester bond hydrolysis | 2.5974 | 6 | yes |
| GO:0090502 | RNA phosphodiester bond hydrolysis, endonucleolytic | 2.5974 | 7 | yes |
| GO:0098795 | global gene silencing by mRNA cleavage | 2.5974 | 8 | yes |
| GO:0120039 | plasma membrane bounded cell projection morphogenesis | 2.5974 | 6 | yes |
| GO:1903555 | regulation of tumor necrosis factor superfamily cytokine production | 2.5974 | 5 | yes |
| GO:1903556 | negative regulation of tumor necrosis factor superfamily cytokine production | 2.5974 | 6 | yes |
Disease
| Term | Name | % | Distance from top the of the tree | Annotated in DICER_HUMAN |
|---|---|---|---|---|
| DOID:331 | central nervous system disease | 3.8961 | 3 | no |
| DOID:480 | movement disease | 3.8961 | 5 | no |
| DOID:936 | brain disease | 3.8961 | 4 | no |
| DOID:543 | dystonia | 2.5974 | 6 | no |
All partners
| Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
|---|---|---|---|---|
| AGO2_HUMAN | [view interactions] | Low throughput | no | yes |
| PIWL4_HUMAN | [view interactions] | Low throughput | no | yes |
| TRBP2_HUMAN | [view interactions] | Low throughput | no | yes |
| TNF12_HUMAN | [view interactions] | Low throughput | no | yes |
| PRKRA_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| AGO1_HUMAN | [view interactions] | Low throughput | no | no |
| DSRAD_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| AGO3_HUMAN | [view interactions] | Low throughput | no | yes |
| DDX4_HUMAN | [view interactions] | Low throughput | no | no |
| FUBP2_HUMAN | [view interactions] | Low throughput | no | yes |
| DHX9_HUMAN | [view interactions] | Low throughput | no | yes |
| NU153_HUMAN | [view interactions] | Low throughput | no | yes |
| PIWL1_HUMAN | [view interactions] | Low throughput | no | no |
| GEMI4_HUMAN | [view interactions] | Low throughput | no | yes |
| LEUK_HUMAN | [view interactions] | Low throughput | no | no |
| RPB1_HUMAN | [view interactions] | Low throughput | no | no |
| IMB1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| RBM3_HUMAN | [view interactions] | Low throughput | no | no |
| DICER_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| NCOA6_HUMAN | [view interactions] | Low throughput | no | yes |
| LOX5_HUMAN | [view interactions] | Low throughput | no | no |
| AGO4_HUMAN | [view interactions] | Low throughput | no | no |
| PIWL3_HUMAN | [view interactions] | Low throughput | no | no |
| PIWL2_HUMAN | [view interactions] | Low throughput | no | no |
| CACO2_HUMAN | [view interactions] | Low throughput | no | yes |
| CUL4A_HUMAN | [view interactions] | Low throughput | no | no |
| LIN41_HUMAN | [view interactions] | Low throughput | no | no |
| TRI25_HUMAN | [view interactions] | Low throughput | no | yes |
| KALRN_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DNJC2_HUMAN | [view interactions] | High throughput | no | yes |
| GOGA1_HUMAN | [view interactions] | High throughput | no | yes |
| AAKB2_HUMAN | [view interactions] | High throughput | no | yes |
| MED9_HUMAN | [view interactions] | High throughput | no | no |
| MED29_HUMAN | [view interactions] | High throughput | no | no |
| UBP49_HUMAN | [view interactions] | High throughput | no | yes |
| DHX58_HUMAN | [view interactions] | High throughput | no | yes |
| E2AK2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HDA11_HUMAN | [view interactions] | High throughput | no | no |
| MD2L2_HUMAN | [view interactions] | High throughput | no | yes |
| TIM13_HUMAN | [view interactions] | High throughput | no | yes |
| SGTB_HUMAN | [view interactions] | High throughput | no | yes |
| HNRPD_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HNRPQ_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SORT_HUMAN | [view interactions] | High throughput | no | yes |
| USF1_HUMAN | [view interactions] | High throughput | no | yes |
| ARP5_HUMAN | [view interactions] | High throughput | no | yes |
| RAP1B_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| PRG2_HUMAN | [view interactions] | High throughput | no | no |
| TRM2A_HUMAN | [view interactions] | High throughput | no | yes |
| TRI41_HUMAN | [view interactions] | High throughput | no | yes |
| AURKA_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ATS4_HUMAN | [view interactions] | High throughput | no | yes |
| RL15_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| FX4L6_HUMAN | [view interactions] | High throughput | no | no |
| CBPA6_HUMAN | [view interactions] | High throughput | no | no |
| FXL14_HUMAN | [view interactions] | High throughput | no | yes |
| FUS_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RS3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RL8_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RS4X_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RS3A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RS2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ADT3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ADT2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HNRPC_HUMAN | [view interactions] | High throughput | no | yes |
| SEC13_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ROA2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PCBP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CAHM1_HUMAN | [view interactions] | High throughput | no | yes |
| ROA1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RBMX_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| G3BP2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CH60_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FUBP3_HUMAN | [view interactions] | High throughput | no | yes |
| YTHD2_HUMAN | [view interactions] | High throughput | no | yes |
| IF2B1_HUMAN | [view interactions] | High throughput | no | no |
| IF2B3_HUMAN | [view interactions] | High throughput | no | no |
| YTHD3_HUMAN | [view interactions] | High throughput | no | no |
| IF2B2_HUMAN | [view interactions] | High throughput | no | yes |
| LARP7_HUMAN | [view interactions] | High throughput | no | yes |
| FUBP1_HUMAN | [view interactions] | High throughput | no | yes |
| EWS_HUMAN | [view interactions] | High throughput | no | yes |
| DDX5_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RBM14_HUMAN | [view interactions] | High throughput | no | yes |
| FXR1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PABP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PABP4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HSP7C_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HNRPR_HUMAN | [view interactions] | High throughput | no | yes |
| FMR1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DDX17_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GRP75_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FXR2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CMC1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SFPQ_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CASC3_HUMAN | [view interactions] | High throughput | no | yes |
| HNRPM_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CAPR1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DDX1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NUP88_HUMAN | [view interactions] | High throughput | no | yes |
| HNRPU_HUMAN | [view interactions] | High throughput | no | yes |
| DHX15_HUMAN | [view interactions] | High throughput | no | yes |
| MATR3_HUMAN | [view interactions] | High throughput | no | yes |
| NUP98_HUMAN | [view interactions] | High throughput | no | no |
| TR150_HUMAN | [view interactions] | High throughput | no | yes |
| ATX2L_HUMAN | [view interactions] | High throughput | no | no |
| PUM2_HUMAN | [view interactions] | High throughput | no | yes |
| UBP2L_HUMAN | [view interactions] | High throughput | no | yes |
| UBAP2_HUMAN | [view interactions] | High throughput | no | yes |
| ATX2_HUMAN | [view interactions] | High throughput | no | yes |
| F120A_HUMAN | [view interactions] | High throughput | no | yes |
| RENT1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PUM1_HUMAN | [view interactions] | High throughput | no | yes |
| DHX30_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GGYF2_HUMAN | [view interactions] | High throughput | no | yes |
| DHX57_HUMAN | [view interactions] | High throughput | no | no |
| SCAPE_HUMAN | [view interactions] | High throughput | no | yes |
| YTDC2_HUMAN | [view interactions] | High throughput | no | no |
| IF4G1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TNR6B_HUMAN | [view interactions] | High throughput | no | yes |
| NU214_HUMAN | [view interactions] | High throughput | no | no |
| PRC2A_HUMAN | [view interactions] | High throughput | no | yes |
| SC16A_HUMAN | [view interactions] | High throughput | no | yes |
| IMP2L_HUMAN | [view interactions] | High throughput | no | yes |
| P2RY6_HUMAN | [view interactions] | High throughput | no | no |
| TF7L2_HUMAN | [view interactions] | High throughput | no | yes |
| PLK1_HUMAN | [view interactions] | High throughput | no | yes |
| ALBU_HUMAN | [view interactions] | High throughput | no | no |
| DDX20_HUMAN | [view interactions] | High throughput | no | no |
| HSC20_HUMAN | [view interactions] | High throughput | no | yes |
| PKHA7_HUMAN | [view interactions] | High throughput | no | yes |
| XPO1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PRIO_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| BMI1_HUMAN | [view interactions] | High throughput | no | yes |
| CUL3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CFA20_HUMAN | [view interactions] | High throughput | no | yes |
| ESR1_HUMAN | [view interactions] | High throughput | no | no |
| CEP19_HUMAN | [view interactions] | High throughput | no | no |
| RBM47_HUMAN | [view interactions] | High throughput | no | yes |
| SIR7_HUMAN | [view interactions] | High throughput | no | yes |
| NOS2_HUMAN | [view interactions] | High throughput | no | yes |
| MMS19_HUMAN | [view interactions] | High throughput | no | yes |
| NPM_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SMN_HUMAN | [view interactions] | High throughput | no | yes |
| MTFR2_HUMAN | [view interactions] | High throughput | no | no |
| NOG2_HUMAN | [view interactions] | High throughput | no | yes |
| GTPB4_HUMAN | [view interactions] | High throughput | no | yes |
| MTFR1_HUMAN | [view interactions] | High throughput | no | yes |
| MYSM1_HUMAN | [view interactions] | High throughput | no | yes |
| NOC3L_HUMAN | [view interactions] | High throughput | no | no |
| POP1_HUMAN | [view interactions] | High throughput | no | no |
| STAU2_HUMAN | [view interactions] | High throughput | no | yes |
| CCDC8_HUMAN | [view interactions] | High throughput | no | yes |
| ZMAT3_HUMAN | [view interactions] | High throughput | no | yes |
| MEMO1_HUMAN | [view interactions] | High throughput | no | yes |
| PNKD_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SFRP4_HUMAN | [view interactions] | High throughput | no | no |
| ILF2_HUMAN | [view interactions] | High throughput | no | yes |
| AAMP_HUMAN | [view interactions] | High throughput | no | yes |
| UBP7_HUMAN | [view interactions] | High throughput | no | yes |
| NTRK1_HUMAN | [view interactions] | High throughput | no | yes |
| CRY2_HUMAN | [view interactions] | High throughput | no | yes |
| IFIX_HUMAN | [view interactions] | High throughput | no | no |
| STRBP_HUMAN | [view interactions] | High throughput | no | yes |
| IQCN_HUMAN | [view interactions] | High throughput | no | no |
| IN80B_HUMAN | [view interactions] | High throughput | no | no |
| FKBP5_HUMAN | [view interactions] | High throughput | no | yes |
| EGLN3_HUMAN | [view interactions] | High throughput | no | no |
| RECQ4_HUMAN | [view interactions] | High throughput | no | yes |
| VIR_HUMAN | [view interactions] | High throughput | no | yes |
| DUS10_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DUS15_HUMAN | [view interactions] | High throughput | no | no |
| DUS2_HUMAN | [view interactions] | High throughput | no | no |
| DUS26_HUMAN | [view interactions] | High throughput | no | yes |
| TP4A3_HUMAN | [view interactions] | High throughput | no | no |
| PTPM1_HUMAN | [view interactions] | High throughput | no | yes |
| TPTE2_HUMAN | [view interactions] | High throughput | no | no |
| STAU1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PKHA4_HUMAN | [view interactions] | High throughput | no | yes |
| LRC31_HUMAN | [view interactions] | High throughput | no | no |
| BRD1_HUMAN | [view interactions] | High throughput | no | yes |
| DJC15_HUMAN | [view interactions] | High throughput | no | no |
| TIM14_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DDX58_HUMAN | [view interactions] | High throughput | no | yes |
| TULP3_HUMAN | [view interactions] | High throughput | no | yes |
| SSF1_HUMAN | [view interactions] | High throughput | no | yes |
| GHC2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RP25L_HUMAN | [view interactions] | High throughput | no | yes |
| RL27A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| EMIL3_HUMAN | [view interactions] | High throughput | no | yes |
| C2C4B_HUMAN | [view interactions] | High throughput | no | no |
| LECT2_HUMAN | [view interactions] | High throughput | no | no |
| PIF1_HUMAN | [view interactions] | High throughput | no | yes |
| NOGG_HUMAN | [view interactions] | High throughput | no | yes |
| ATS13_HUMAN | [view interactions] | High throughput | no | no |
| SOCS1_HUMAN | [view interactions] | High throughput | no | yes |
| MCM5_HUMAN | [view interactions] | High throughput | no | no |
| PHF1_HUMAN | [view interactions] | High throughput | no | yes |
| HPSE2_HUMAN | [view interactions] | High throughput | no | yes |
| SIX5_HUMAN | [view interactions] | High throughput | no | yes |
| DIK1A_HUMAN | [view interactions] | High throughput | no | yes |
| FGF11_HUMAN | [view interactions] | High throughput | no | no |
| IL17B_HUMAN | [view interactions] | High throughput | no | no |
| RL10_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RL13_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RL13A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ZN346_HUMAN | [view interactions] | High throughput | no | yes |
| RL18A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ZMAT4_HUMAN | [view interactions] | High throughput | no | yes |
| EMID1_HUMAN | [view interactions] | High throughput | no | yes |
| RL36L_HUMAN | [view interactions] | High throughput | no | no |
| LN28A_HUMAN | [view interactions] | High throughput | no | no |
| RLA0_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RL7A_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RL3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ZRAN1_HUMAN | [view interactions] | High throughput | no | yes |
| ZN363_HUMAN | [view interactions] | High throughput | no | yes |
| RAF1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| SIR6_HUMAN | [view interactions] | High throughput | no | yes |
| ILF3_HUMAN | [view interactions] | High throughput | no | yes |
| MYO9B_HUMAN | [view interactions] | High throughput | no | yes |
| SRP09_HUMAN | [view interactions] | High throughput | no | no |
| APC13_HUMAN | [view interactions] | High throughput | no | no |
| ARI1_HUMAN | [view interactions] | High throughput | no | yes |
| CENPM_HUMAN | [view interactions] | High throughput | no | yes |
| MED1_HUMAN | [view interactions] | High throughput | no | no |
| SCYL1_HUMAN | [view interactions] | High throughput | no | yes |
| SC22B_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| SRBP2_HUMAN | [view interactions] | High throughput | no | yes |
| RASK_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RIT1_HUMAN | [view interactions] | High throughput | no | yes |
| RL5_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| RL10A_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| DDX6_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| RPP30_HUMAN | [view interactions] | Computational | no | yes |
| RPP25_HUMAN | [view interactions] | Computational | no | yes |
| RPP40_HUMAN | [view interactions] | Computational | no | no |
| POP5_HUMAN | [view interactions] | Computational | no | no |
| LN28B_HUMAN | [view interactions] | Computational | no | no |
| DCP2_HUMAN | [view interactions] | Computational | no | yes |
| RS9_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| RBM8A_HUMAN | [view interactions] | Computational | no | yes |
| TADBP_HUMAN | [view interactions] | Computational | no | yes |
| XRN1_HUMAN | [view interactions] | Computational | no | yes |
| HENMT_HUMAN | [view interactions] | Computational | no | yes |
| EXOSX_HUMAN | [view interactions] | Computational | no | yes |
| HCD2_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| RPP38_HUMAN | [view interactions] | Computational | no | yes |
| RS13_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| RS20_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| RPP21_HUMAN | [view interactions] | Computational | no | no |
| RNC_HUMAN | [view entry] [view interactions] | Computational | yes | no |
| IF6_HUMAN | [view interactions] | Computational | no | yes |
| CLP1_HUMAN | [view interactions] | Computational | no | yes |
| POP7_HUMAN | [view interactions] | Computational | no | yes |
| TYY1_HUMAN | [view interactions] | Computational | no | yes |
| RPP29_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| TNR6A_HUMAN | [view interactions] | Computational | no | yes |
| IF4E_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| RPP14_HUMAN | [view interactions] | Computational | no | no |
| SRRT_HUMAN | [view interactions] | Computational | no | yes |
| MRPP3_HUMAN | [view interactions] | Computational | no | yes |
| PCBP2_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| XPO5_HUMAN | [view interactions] | Computational | no | yes |
| DGCR8_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| RL30_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| LIMD1_HUMAN | [view interactions] | Computational | no | yes |