IF4E_HUMAN
Evidence for PS localization
Functions
Recognizes and binds the 7-methylguanosine-containing mRNA cap during an early step in the initiation of protein synthesis and facilitates ribosome binding by inducing the unwinding of the mRNAs secondary structures (PubMed, PubMed). In addition to its role in translation initiation, also acts as a regulator of translation and stability in the cytoplasm (PubMed). Component of the CYFIP1-EIF4E-FMR1 complex which binds to the mRNA cap and mediates translational repression: in the complex, EIF4E mediates the binding to the mRNA cap . Component of a multiprotein complex that sequesters and represses translation of proneurogenic factors during neurogenesis . In P-bodies, component of a complex that mediates the storage of translationally inactive mRNAs in the cytoplasm and prevents their degradation (PubMed). May play an important role in spermatogenesis through translational regulation of stage-specific mRNAs during germ cell development . [View more on UniProt]
Protein features
Binary interactions with known binding regions
To display all evidence describing the interaction with a partner, click on the protein name left to the bars.
Network
Isoforms
Disease-causing germline mutations
No data found.
Linear motifs
No annotated instance was found. To search for linear motifs, use the ELM prediction server.
Fingerprint
Molecular function
| Term | Name | % | Distance from the top of the tree | Annotated in IF4E_HUMAN |
|---|---|---|---|---|
| GO:0003723 | RNA binding | 55.5556 | 4 | yes |
| GO:0017076 | purine nucleotide binding | 30.5556 | 4 | no |
| GO:0032555 | purine ribonucleotide binding | 30.5556 | 4 | no |
| GO:0035639 | purine ribonucleoside triphosphate binding | 30.5556 | 4 | no |
| GO:0005524 | ATP binding | 25.0000 | 5 | no |
| GO:0030554 | adenyl nucleotide binding | 25.0000 | 5 | no |
| GO:0032559 | adenyl ribonucleotide binding | 25.0000 | 5 | no |
| GO:0019900 | kinase binding | 23.6111 | 4 | no |
| GO:0019901 | protein kinase binding | 22.2222 | 5 | no |
| GO:0046872 | metal ion binding | 20.8333 | 4 | no |
| GO:0003743 | translation initiation factor activity | 12.5000 | 4 | yes |
| GO:0140297 | DNA-binding transcription factor binding | 8.3333 | 4 | yes |
| GO:0000339 | RNA cap binding | 4.1667 | 5 | yes |
| GO:0000340 | RNA 7-methylguanosine cap binding | 4.1667 | 6 | yes |
| GO:0031370 | eukaryotic initiation factor 4G binding | 2.7778 | 4 | yes |
Biological process
| Term | Name | % | Distance from top the of the tree | Annotated in IF4E_HUMAN |
|---|---|---|---|---|
| GO:0031323 | regulation of cellular metabolic process | 80.5556 | 4 | yes |
| GO:0060255 | regulation of macromolecule metabolic process | 79.1667 | 4 | yes |
| GO:0080090 | regulation of primary metabolic process | 77.7778 | 4 | yes |
| GO:0051171 | regulation of nitrogen compound metabolic process | 75.0000 | 4 | yes |
| GO:0048522 | positive regulation of cellular process | 72.2222 | 4 | yes |
| GO:0010468 | regulation of gene expression | 68.0556 | 5 | yes |
| GO:0048523 | negative regulation of cellular process | 68.0556 | 4 | yes |
| GO:0009889 | regulation of biosynthetic process | 63.8889 | 4 | yes |
| GO:0031326 | regulation of cellular biosynthetic process | 63.8889 | 5 | yes |
| GO:0051246 | regulation of protein metabolic process | 62.5000 | 5 | yes |
| GO:0010556 | regulation of macromolecule biosynthetic process | 61.1111 | 5 | yes |
| GO:0009893 | positive regulation of metabolic process | 51.3889 | 4 | no |
| GO:0009892 | negative regulation of metabolic process | 51.3889 | 4 | yes |
| GO:0010604 | positive regulation of macromolecule metabolic process | 50.0000 | 5 | no |
| GO:0031325 | positive regulation of cellular metabolic process | 48.6111 | 5 | no |
| GO:0051173 | positive regulation of nitrogen compound metabolic process | 47.2222 | 5 | no |
| GO:0010608 | post-transcriptional regulation of gene expression | 47.2222 | 6 | yes |
| GO:0010646 | regulation of cell communication | 47.2222 | 4 | yes |
| GO:0031324 | negative regulation of cellular metabolic process | 47.2222 | 5 | yes |
| GO:0010605 | negative regulation of macromolecule metabolic process | 45.8333 | 5 | yes |
| GO:2000112 | regulation of cellular macromolecule biosynthetic process | 45.8333 | 6 | yes |
| GO:0006417 | regulation of translation | 43.0556 | 6 | yes |
| GO:0034248 | regulation of cellular amide metabolic process | 43.0556 | 5 | yes |
| GO:0051172 | negative regulation of nitrogen compound metabolic process | 43.0556 | 5 | yes |
| GO:0009966 | regulation of signal transduction | 38.8889 | 4 | no |
| GO:0051247 | positive regulation of protein metabolic process | 38.8889 | 6 | no |
| GO:0019219 | regulation of nucleobase-containing compound metabolic process | 36.1111 | 5 | no |
| GO:0051128 | regulation of cellular component organization | 36.1111 | 4 | no |
| GO:0051252 | regulation of RNA metabolic process | 34.7222 | 5 | no |
| GO:0009891 | positive regulation of biosynthetic process | 31.9444 | 5 | no |
| GO:0031328 | positive regulation of cellular biosynthetic process | 31.9444 | 6 | no |
| GO:0022607 | cellular component assembly | 31.9444 | 4 | no |
| GO:0010629 | negative regulation of gene expression | 31.9444 | 6 | yes |
| GO:0010557 | positive regulation of macromolecule biosynthetic process | 30.5556 | 6 | no |
| GO:0010628 | positive regulation of gene expression | 30.5556 | 6 | no |
| GO:0048584 | positive regulation of response to stimulus | 30.5556 | 4 | no |
| GO:0051248 | negative regulation of protein metabolic process | 30.5556 | 6 | yes |
| GO:0071310 | cellular response to organic substance | 30.5556 | 4 | yes |
| GO:1902531 | regulation of intracellular signal transduction | 29.1667 | 5 | no |
| GO:0009894 | regulation of catabolic process | 29.1667 | 4 | no |
| GO:0031329 | regulation of cellular catabolic process | 29.1667 | 5 | no |
| GO:0051726 | regulation of cell cycle | 29.1667 | 4 | yes |
| GO:0031399 | regulation of protein modification process | 27.7778 | 6 | no |
| GO:0045595 | regulation of cell differentiation | 27.7778 | 4 | yes |
| GO:0090304 | nucleic acid metabolic process | 26.3889 | 4 | no |
| GO:0006996 | organelle organization | 26.3889 | 4 | no |
| GO:0010647 | positive regulation of cell communication | 26.3889 | 5 | no |
| GO:0023056 | positive regulation of signaling | 26.3889 | 4 | no |
| GO:0009890 | negative regulation of biosynthetic process | 26.3889 | 5 | yes |
| GO:0010558 | negative regulation of macromolecule biosynthetic process | 26.3889 | 6 | yes |
| GO:0031327 | negative regulation of cellular biosynthetic process | 26.3889 | 6 | yes |
| GO:0019220 | regulation of phosphate metabolic process | 25.0000 | 6 | no |
| GO:0043412 | macromolecule modification | 25.0000 | 4 | no |
| GO:0051174 | regulation of phosphorus metabolic process | 25.0000 | 5 | no |
| GO:0010648 | negative regulation of cell communication | 23.6111 | 5 | no |
| GO:0016070 | RNA metabolic process | 23.6111 | 5 | no |
| GO:0023057 | negative regulation of signaling | 23.6111 | 4 | no |
| GO:0031401 | positive regulation of protein modification process | 23.6111 | 7 | no |
| GO:0036211 | protein modification process | 23.6111 | 4 | no |
| GO:0043085 | positive regulation of catalytic activity | 23.6111 | 4 | no |
| GO:0010941 | regulation of cell death | 23.6111 | 4 | no |
| GO:0009967 | positive regulation of signal transduction | 23.6111 | 5 | no |
| GO:0009968 | negative regulation of signal transduction | 22.2222 | 5 | no |
| GO:0042325 | regulation of phosphorylation | 22.2222 | 7 | no |
| GO:0048585 | negative regulation of response to stimulus | 22.2222 | 4 | no |
| GO:0008104 | protein localization | 22.2222 | 4 | no |
| GO:1901701 | cellular response to oxygen-containing compound | 22.2222 | 4 | yes |
| GO:0001932 | regulation of protein phosphorylation | 20.8333 | 7 | no |
| GO:0006396 | RNA processing | 20.8333 | 6 | no |
| GO:0010562 | positive regulation of phosphorus metabolic process | 20.8333 | 6 | no |
| GO:0045937 | positive regulation of phosphate metabolic process | 20.8333 | 7 | no |
| GO:0051338 | regulation of transferase activity | 20.8333 | 4 | no |
| GO:1903506 | regulation of nucleic acid-templated transcription | 20.8333 | 7 | no |
| GO:2001141 | regulation of RNA biosynthetic process | 20.8333 | 6 | no |
| GO:0009059 | macromolecule biosynthetic process | 20.8333 | 4 | no |
| GO:0034645 | cellular macromolecule biosynthetic process | 20.8333 | 4 | no |
| GO:0043067 | regulation of programmed cell death | 20.8333 | 5 | no |
| GO:0051049 | regulation of transport | 20.8333 | 4 | no |
| GO:0034250 | positive regulation of cellular amide metabolic process | 20.8333 | 6 | no |
| GO:0051130 | positive regulation of cellular component organization | 20.8333 | 5 | no |
| GO:0007346 | regulation of mitotic cell cycle | 20.8333 | 5 | yes |
| GO:2000113 | negative regulation of cellular macromolecule biosynthetic process | 18.0556 | 7 | yes |
| GO:0017148 | negative regulation of translation | 18.0556 | 7 | yes |
| GO:0034249 | negative regulation of cellular amide metabolic process | 18.0556 | 6 | yes |
| GO:0051093 | negative regulation of developmental process | 16.6667 | 4 | yes |
| GO:0045596 | negative regulation of cell differentiation | 15.2778 | 5 | yes |
| GO:0050804 | modulation of chemical synaptic transmission | 15.2778 | 5 | yes |
| GO:0099177 | regulation of trans-synaptic signaling | 15.2778 | 4 | yes |
| GO:0045787 | positive regulation of cell cycle | 13.8889 | 5 | yes |
| GO:0014070 | response to organic cyclic compound | 12.5000 | 4 | yes |
| GO:0033993 | response to lipid | 11.1111 | 4 | yes |
| GO:0045931 | positive regulation of mitotic cell cycle | 11.1111 | 6 | yes |
| GO:0071407 | cellular response to organic cyclic compound | 11.1111 | 5 | yes |
| GO:0032870 | cellular response to hormone stimulus | 9.7222 | 4 | yes |
| GO:0071396 | cellular response to lipid | 9.7222 | 5 | yes |
| GO:0000082 | G1/S transition of mitotic cell cycle | 6.9444 | 5 | yes |
| GO:0044772 | mitotic cell cycle phase transition | 6.9444 | 4 | yes |
| GO:0044843 | cell cycle G1/S phase transition | 6.9444 | 4 | yes |
| GO:0045664 | regulation of neuron differentiation | 6.9444 | 5 | yes |
| GO:1901654 | response to ketone | 6.9444 | 4 | yes |
| GO:1901655 | cellular response to ketone | 6.9444 | 5 | yes |
| GO:0001662 | behavioral fear response | 5.5556 | 4 | yes |
| GO:0045665 | negative regulation of neuron differentiation | 5.5556 | 6 | yes |
| GO:0099170 | postsynaptic modulation of chemical synaptic transmission | 5.5556 | 6 | yes |
| GO:0031960 | response to corticosteroid | 4.1667 | 5 | yes |
| GO:0048545 | response to steroid hormone | 4.1667 | 4 | yes |
| GO:0051384 | response to glucocorticoid | 4.1667 | 6 | yes |
| GO:0071383 | cellular response to steroid hormone stimulus | 4.1667 | 5 | yes |
| GO:0071384 | cellular response to corticosteroid stimulus | 4.1667 | 6 | yes |
| GO:0071385 | cellular response to glucocorticoid stimulus | 4.1667 | 7 | yes |
| GO:0071548 | response to dexamethasone | 4.1667 | 5 | yes |
| GO:0071549 | cellular response to dexamethasone stimulus | 4.1667 | 6 | yes |
| GO:0099547 | regulation of translation at synapse, modulating synaptic transmission | 4.1667 | 6 | yes |
| GO:0099578 | regulation of translation at postsynapse, modulating synaptic transmission | 4.1667 | 7 | yes |
| GO:0140243 | regulation of translation at synapse | 4.1667 | 7 | yes |
| GO:0140245 | regulation of translation at postsynapse | 4.1667 | 8 | yes |
Disease
| Term | Name | % | Distance from top the of the tree | Annotated in IF4E_HUMAN |
|---|---|---|---|---|
| DOID:0050686 | organ system cancer | 2.7778 | 3 | no |
| DOID:6457 | Cowden syndrome | 2.7778 | 3 | no |
| DOID:37 | skin disease | 2.7778 | 3 | no |
All partners
| Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
|---|---|---|---|---|
| IF4G1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| LPPRC_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| AGO2_HUMAN | [view interactions] | Low throughput | no | yes |
| 4EBP2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| IF4A1_HUMAN | [view interactions] | Low throughput | no | no |
| RBM4_HUMAN | [view interactions] | Low throughput | no | yes |
| BTG4_HUMAN | [view interactions] | Low throughput | no | no |
| 4EBP3_HUMAN | [view interactions] | Low throughput | no | yes |
| MKNK1_HUMAN | [view interactions] | Low throughput | no | yes |
| EMX2_HUMAN | [view interactions] | Low throughput | no | yes |
| GEMI5_HUMAN | [view interactions] | Low throughput | no | yes |
| CYFP1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| FMR1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| RS6_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| EIF3B_HUMAN | [view interactions] | Low throughput | no | yes |
| INT6_HUMAN | [view interactions] | Low throughput | no | yes |
| DDX3X_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| PML_HUMAN | [view interactions] | Low throughput | no | yes |
| SUMO1_HUMAN | [view interactions] | Low throughput | no | yes |
| PP2AA_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| IRS1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| EIF3A_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| EIF3F_HUMAN | [view interactions] | Low throughput | no | yes |
| G3BP1_HUMAN | [view interactions] | Low throughput | no | yes |
| IF4E_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| CHIP_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| DCC_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| HSPB2_HUMAN | [view interactions] | Low throughput | no | yes |
| TRI22_HUMAN | [view interactions] | Low throughput | no | yes |
| OTU6B_HUMAN | [view interactions] | Low throughput | no | yes |
| BIRC2_HUMAN | [view interactions] | Low throughput | no | yes |
| ELAV1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| SRSF3_HUMAN | [view interactions] | Low throughput | no | yes |
| MTA70_HUMAN | [view interactions] | Low throughput | no | no |
| IKBZ_HUMAN | [view interactions] | Low throughput | no | no |
| MYC_HUMAN | [view interactions] | Low throughput | no | yes |
| 4ET_HUMAN | [view interactions] | Low throughput | no | yes |
| 4EBP1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| IF4G3_HUMAN | [view interactions] | Low throughput | no | yes |
| GLUT4_HUMAN | [view interactions] | High throughput | no | no |
| EIF3H_HUMAN | [view interactions] | High throughput | no | yes |
| HIF1N_HUMAN | [view interactions] | High throughput | no | yes |
| ANGE1_HUMAN | [view interactions] | High throughput | no | yes |
| PABP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RENT1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| BTG2_HUMAN | [view interactions] | High throughput | no | yes |
| CNOT7_HUMAN | [view interactions] | High throughput | no | no |
| BTG3_HUMAN | [view interactions] | High throughput | no | yes |
| MOT11_HUMAN | [view interactions] | High throughput | no | no |
| VCAM1_HUMAN | [view interactions] | High throughput | no | no |
| GGYF2_HUMAN | [view interactions] | High throughput | no | yes |
| IF4A2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PAK2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| SMYD2_HUMAN | [view interactions] | High throughput | no | yes |
| TRAF6_HUMAN | [view interactions] | High throughput | no | yes |
| KS6B1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MTOR_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NXF1_HUMAN | [view interactions] | High throughput | no | yes |
| DX39B_HUMAN | [view interactions] | High throughput | no | no |
| ROA1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NCBP1_HUMAN | [view interactions] | High throughput | no | yes |
| SATB2_HUMAN | [view interactions] | High throughput | no | yes |
| BMI1_HUMAN | [view interactions] | High throughput | no | yes |
| CD83_HUMAN | [view interactions] | High throughput | no | yes |
| PRDM4_HUMAN | [view interactions] | High throughput | no | no |
| TRI27_HUMAN | [view interactions] | High throughput | no | yes |
| T23O_HUMAN | [view interactions] | High throughput | no | no |
| UBX11_HUMAN | [view interactions] | High throughput | no | yes |
| KANK2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ESR1_HUMAN | [view interactions] | High throughput | no | no |
| EIF3E_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| EIF3M_HUMAN | [view interactions] | High throughput | no | yes |
| RS27L_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| EIF3K_HUMAN | [view interactions] | High throughput | no | yes |
| EIF3C_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| EIF3I_HUMAN | [view interactions] | High throughput | no | yes |
| EIF3L_HUMAN | [view interactions] | High throughput | no | yes |
| EIF3G_HUMAN | [view interactions] | High throughput | no | yes |
| EIF3D_HUMAN | [view interactions] | High throughput | no | yes |
| RPTOR_HUMAN | [view interactions] | High throughput | no | yes |
| ITA4_HUMAN | [view interactions] | High throughput | no | no |
| NTRK1_HUMAN | [view interactions] | High throughput | no | yes |
| IFIX_HUMAN | [view interactions] | High throughput | no | no |
| CYLD_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| U5S1_HUMAN | [view interactions] | High throughput | no | yes |
| PIHD1_HUMAN | [view interactions] | High throughput | no | yes |
| ESR2_HUMAN | [view interactions] | High throughput | no | no |
| RN123_HUMAN | [view interactions] | High throughput | no | yes |
| RECQ4_HUMAN | [view interactions] | High throughput | no | yes |
| CDK9_HUMAN | [view interactions] | High throughput | no | yes |
| GLUC_HUMAN | [view interactions] | High throughput | no | no |
| BIRC3_HUMAN | [view interactions] | High throughput | no | no |
| NFX1_HUMAN | [view interactions] | High throughput | no | yes |
| CTNB1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PKHA4_HUMAN | [view interactions] | High throughput | no | yes |
| MT21E_HUMAN | [view interactions] | High throughput | no | no |
| FZR1_HUMAN | [view interactions] | High throughput | no | no |
| DDRGK_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| WDR5_HUMAN | [view interactions] | High throughput | no | no |
| I4E1B_HUMAN | [view interactions] | High throughput | no | no |
| POTEF_HUMAN | [view interactions] | High throughput | no | no |
| ATG13_HUMAN | [view interactions] | High throughput | no | no |
| ATG4B_HUMAN | [view interactions] | High throughput | no | yes |
| CAPR1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CAPZB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CASP3_HUMAN | [view interactions] | High throughput | no | yes |
| DDX6_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DRG1_HUMAN | [view interactions] | High throughput | no | yes |
| IF2G_HUMAN | [view interactions] | High throughput | no | yes |
| IF5_HUMAN | [view interactions] | High throughput | no | yes |
| ERF3A_HUMAN | [view interactions] | High throughput | no | yes |
| LS14A_HUMAN | [view interactions] | High throughput | no | yes |
| MAP2_HUMAN | [view interactions] | High throughput | no | yes |
| PDZD8_HUMAN | [view interactions] | High throughput | no | yes |
| PSPC1_HUMAN | [view interactions] | High throughput | no | yes |
| RACK1_HUMAN | [view interactions] | High throughput | no | yes |
| RBM42_HUMAN | [view interactions] | High throughput | no | yes |
| RBM8A_HUMAN | [view interactions] | High throughput | no | yes |
| RL5_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RS16_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SRP68_HUMAN | [view interactions] | High throughput | no | yes |
| SRP72_HUMAN | [view interactions] | High throughput | no | yes |
| WDR3_HUMAN | [view interactions] | High throughput | no | no |
| EGFR_HUMAN | [view interactions] | High throughput | no | no |
| RASK_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RIT1_HUMAN | [view interactions] | High throughput | no | yes |
| A4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| OTUD4_HUMAN | [view interactions] | High throughput | no | yes |
| PTEN_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| IF4H_HUMAN | [view interactions] | High throughput | no | yes |
| AHSA1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ASSY_HUMAN | [view interactions] | High throughput | no | yes |
| CAN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GRP75_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SIAS_HUMAN | [view interactions] | High throughput | no | yes |
| IF6_HUMAN | [view interactions] | High throughput | no | yes |
| CH60_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PEPD_HUMAN | [view interactions] | High throughput | no | yes |
| PLPHP_HUMAN | [view interactions] | High throughput | no | yes |
| TYPH_HUMAN | [view interactions] | High throughput | no | no |
| DD19A_HUMAN | [view interactions] | High throughput | no | yes |
| CSK_HUMAN | [view interactions] | High throughput | no | yes |
| UBFD1_HUMAN | [view interactions] | High throughput | no | no |
| ECM29_HUMAN | [view interactions] | High throughput | no | no |
| PABP3_HUMAN | [view interactions] | High throughput | no | yes |
| PABP4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PDXK_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DI3L2_HUMAN | [view interactions] | High throughput | no | yes |
| RAC1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RAMAC_HUMAN | [view interactions] | High throughput | no | yes |
| HNRPU_HUMAN | [view interactions] | High throughput | no | yes |
| IQGA1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| LARP1_HUMAN | [view interactions] | High throughput | no | yes |
| MCRI1_HUMAN | [view interactions] | High throughput | no | yes |
| MCES_HUMAN | [view interactions] | High throughput | no | yes |
| ROCK2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TBB5_HUMAN | [view interactions] | High throughput | no | yes |
| DDX1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ACTB_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ATX2_HUMAN | [view interactions] | High throughput | no | yes |
| DHX9_HUMAN | [view interactions] | High throughput | no | yes |
| NUCL_HUMAN | [view interactions] | High throughput | no | yes |
| PCBP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RL13_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RL6_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RS4X_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TIA1_HUMAN | [view interactions] | High throughput | no | no |
| YBOX1_HUMAN | [view interactions] | High throughput | no | yes |
| IF4G2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KPCB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PSMD6_HUMAN | [view interactions] | High throughput | no | yes |
| ATX2L_HUMAN | [view interactions] | High throughput | no | no |
| CATH_HUMAN | [view interactions] | High throughput | no | no |
| RL28_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PDIP3_HUMAN | [view interactions] | High throughput | no | no |
| STAU1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DC1I1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DCP1A_HUMAN | [view interactions] | High throughput | no | yes |
| PATL1_HUMAN | [view interactions] | High throughput | no | yes |
| YTHD2_HUMAN | [view interactions] | High throughput | no | yes |
| TTP_HUMAN | [view interactions] | High throughput | no | yes |
| CELF1_HUMAN | [view interactions] | High throughput | no | yes |
| CC177_HUMAN | [view interactions] | High throughput | no | no |
| TFG_HUMAN | [view interactions] | High throughput | no | yes |
| AT8OS_HUMAN | [view interactions] | High throughput | no | no |
| CH088_HUMAN | [view interactions] | High throughput | no | no |
| GGYF1_HUMAN | [view interactions] | High throughput | no | yes |
| NU188_HUMAN | [view interactions] | Computational | no | yes |
| CNO10_HUMAN | [view interactions] | Computational | no | yes |
| PAN2_HUMAN | [view interactions] | Computational | no | no |
| CASP9_HUMAN | [view interactions] | Computational | no | yes |
| IF4E2_HUMAN | [view interactions] | Computational | no | no |
| CNO11_HUMAN | [view interactions] | Computational | no | yes |
| CASP8_HUMAN | [view interactions] | Computational | no | yes |
| CNOT4_HUMAN | [view interactions] | Computational | no | yes |
| NDC1_HUMAN | [view interactions] | Computational | no | yes |
| PIWL1_HUMAN | [view interactions] | Computational | no | no |
| NUP50_HUMAN | [view interactions] | Computational | no | yes |
| NCB2L_HUMAN | [view interactions] | Computational | no | no |
| LSM1_HUMAN | [view interactions] | Computational | no | no |
| INS_HUMAN | [view interactions] | Computational | no | no |
| NCBP3_HUMAN | [view interactions] | Computational | no | yes |
| CASP1_HUMAN | [view interactions] | Computational | no | yes |
| AKTS1_HUMAN | [view interactions] | Computational | no | yes |
| EIF1_HUMAN | [view interactions] | Computational | no | no |
| XRN1_HUMAN | [view interactions] | Computational | no | yes |
| RBP2_HUMAN | [view interactions] | Computational | no | yes |
| CNO6L_HUMAN | [view interactions] | Computational | no | no |
| XPO1_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| CNOT9_HUMAN | [view interactions] | Computational | no | yes |
| NUP58_HUMAN | [view interactions] | Computational | no | yes |
| AAAS_HUMAN | [view interactions] | Computational | no | yes |
| LTOR4_HUMAN | [view interactions] | Computational | no | yes |
| TPR_HUMAN | [view interactions] | Computational | no | yes |
| HXA9_HUMAN | [view interactions] | Computational | no | yes |
| AGO4_HUMAN | [view interactions] | Computational | no | no |
| NGDN_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| IF2P_HUMAN | [view interactions] | Computational | no | yes |
| NU160_HUMAN | [view interactions] | Computational | no | no |
| NUP98_HUMAN | [view interactions] | Computational | no | no |
| MK14_HUMAN | [view interactions] | Computational | no | yes |
| PAN3_HUMAN | [view interactions] | Computational | no | yes |
| CASP5_HUMAN | [view interactions] | Computational | no | no |
| CASP4_HUMAN | [view interactions] | Computational | no | yes |
| LTOR1_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| PRS6B_HUMAN | [view interactions] | Computational | no | yes |
| RRAGD_HUMAN | [view interactions] | Computational | no | yes |
| RRAGC_HUMAN | [view interactions] | Computational | no | yes |
| AGO3_HUMAN | [view interactions] | Computational | no | yes |
| ATP7A_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| RAE1L_HUMAN | [view interactions] | Computational | no | no |
| NUP62_HUMAN | [view interactions] | Computational | no | yes |
| TNR6A_HUMAN | [view interactions] | Computational | no | yes |
| RHEB_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| PO210_HUMAN | [view interactions] | Computational | no | yes |
| NUP43_HUMAN | [view interactions] | Computational | no | yes |
| CASP2_HUMAN | [view interactions] | Computational | no | yes |
| CNOT6_HUMAN | [view interactions] | Computational | no | yes |
| NUP54_HUMAN | [view interactions] | Computational | no | yes |
| LTOR3_HUMAN | [view interactions] | Computational | no | yes |
| IF2B_HUMAN | [view interactions] | Computational | no | yes |
| NU133_HUMAN | [view interactions] | Computational | no | yes |
| HSPB3_HUMAN | [view interactions] | Computational | no | no |
| XPO5_HUMAN | [view interactions] | Computational | no | yes |
| PDCD4_HUMAN | [view interactions] | Computational | no | yes |
| P121A_HUMAN | [view interactions] | Computational | no | yes |
| DICER_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| TRBP2_HUMAN | [view interactions] | Computational | no | yes |
| SLBP_HUMAN | [view interactions] | Computational | no | yes |
| PTBP2_HUMAN | [view interactions] | Computational | no | no |
| NUP35_HUMAN | [view interactions] | Computational | no | yes |
| NUP93_HUMAN | [view interactions] | Computational | no | yes |
| NUP85_HUMAN | [view interactions] | Computational | no | yes |
| PARN_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| NU107_HUMAN | [view interactions] | Computational | no | no |
| TUT7_HUMAN | [view interactions] | Computational | no | yes |
| S38A9_HUMAN | [view interactions] | Computational | no | yes |
| PTBP1_HUMAN | [view interactions] | Computational | no | no |
| CNOT1_HUMAN | [view interactions] | Computational | no | yes |
| TB182_HUMAN | [view interactions] | Computational | no | yes |
| CASP6_HUMAN | [view interactions] | Computational | no | no |
| P121C_HUMAN | [view interactions] | Computational | no | yes |
| CNOT2_HUMAN | [view interactions] | Computational | no | yes |
| 2A5D_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| NU153_HUMAN | [view interactions] | Computational | no | yes |
| NUP37_HUMAN | [view interactions] | Computational | no | yes |
| E2AK4_HUMAN | [view interactions] | Computational | no | yes |
| LIMD1_HUMAN | [view interactions] | Computational | no | yes |
| CASPA_HUMAN | [view interactions] | Computational | no | yes |
| MKNK2_HUMAN | [view interactions] | Computational | no | yes |
| CPEB1_HUMAN | [view entry] [view interactions] | Computational | yes | no |
| RRAGB_HUMAN | [view interactions] | Computational | no | yes |
| AGO1_HUMAN | [view interactions] | Computational | no | no |
| CNOT3_HUMAN | [view interactions] | Computational | no | yes |
| MK11_HUMAN | [view interactions] | Computational | no | yes |
| PAIP1_HUMAN | [view interactions] | Computational | no | yes |
| EDC3_HUMAN | [view interactions] | Computational | no | yes |
| NU155_HUMAN | [view interactions] | Computational | no | yes |
| LST8_HUMAN | [view interactions] | Computational | no | yes |
| NUP42_HUMAN | [view interactions] | Computational | no | no |
| SEH1_HUMAN | [view interactions] | Computational | no | no |
| AKT1_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| NU214_HUMAN | [view interactions] | Computational | no | no |
| DCP2_HUMAN | [view interactions] | Computational | no | yes |
| SEC13_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| RRAGA_HUMAN | [view interactions] | Computational | no | yes |
| IF2A_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| 1433B_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| NUP88_HUMAN | [view interactions] | Computational | no | yes |
| EF2_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| CNOT8_HUMAN | [view interactions] | Computational | no | yes |
| NU205_HUMAN | [view interactions] | Computational | no | no |
| LTOR2_HUMAN | [view interactions] | Computational | no | yes |
| NCBP2_HUMAN | [view interactions] | Computational | no | yes |
| FKB1A_HUMAN | [view interactions] | Computational | no | yes |