SUMO1_HUMAN
Evidence for PS localization
Functions
Ubiquitin-like protein that can be covalently attached to proteins as a monomer or a lysine-linked polymer. Covalent attachment via an isopeptide bond to its substrates requires prior activation by the E1 complex SAE1-SAE2 and linkage to the E2 enzyme UBE2I, and can be promoted by E3 ligases such as PIAS1-4, RANBP2 or CBX4. This post-translational modification on lysine residues of proteins plays a crucial role in a number of cellular processes such as nuclear transport, DNA replication and repair, mitosis and signal transduction. Involved for instance in targeting RANGAP1 to the nuclear pore complex protein RANBP2. Covalently attached to the voltage-gated potassium channel KCNB1; this modulates the gating characteristics of KCNB1 (PubMed). Polymeric SUMO1 chains are also susceptible to polyubiquitination which functions as a signal for proteasomal degradation of modified proteins. May also regulate a network of genes involved in palate development. Covalently attached to ZFHX3 (PubMed). [View more on UniProt]
Protein features
Binary interactions with known binding regions
To display all evidence describing the interaction with a partner, click on the protein name left to the bars.
Network
Isoforms
Disease-causing germline mutations
No data found.
Linear motifs
| ELM instance | Name | Type | Start | End | Partner |
|---|---|---|---|---|---|
| ELMI002864 | MOD_SUMO_rev_2 | MOD | 3 | 8 | - |
| ELMI002864 | MOD_SUMO_rev_2 | MOD | 3 | 8 | - |
Fingerprint
Molecular function
| Term | Name | % | Distance from the top of the tree | Annotated in SUMO1_HUMAN |
|---|---|---|---|---|
| GO:0003723 | RNA binding | 39.4737 | 4 | yes |
| GO:0043169 | cation binding | 31.5789 | 4 | no |
| GO:0046872 | metal ion binding | 30.2632 | 5 | no |
| GO:0044389 | ubiquitin-like protein ligase binding | 22.3684 | 4 | yes |
| GO:0031625 | ubiquitin protein ligase binding | 19.7368 | 5 | yes |
| GO:0002020 | protease binding | 10.5263 | 4 | yes |
| GO:0044388 | small protein activating enzyme binding | 6.5789 | 4 | yes |
| GO:1990381 | ubiquitin-specific protease binding | 6.5789 | 5 | yes |
| GO:0015459 | potassium channel regulator activity | 3.9474 | 5 | yes |
| GO:0099106 | ion channel regulator activity | 3.9474 | 4 | yes |
Biological process
| Term | Name | % | Distance from top the of the tree | Annotated in SUMO1_HUMAN |
|---|---|---|---|---|
| GO:0048522 | positive regulation of cellular process | 67.1053 | 4 | yes |
| GO:0048523 | negative regulation of cellular process | 63.1579 | 4 | yes |
| GO:0060255 | regulation of macromolecule metabolic process | 61.8421 | 4 | yes |
| GO:0080090 | regulation of primary metabolic process | 61.8421 | 4 | yes |
| GO:0031323 | regulation of cellular metabolic process | 59.2105 | 4 | yes |
| GO:0009889 | regulation of biosynthetic process | 51.3158 | 4 | yes |
| GO:0009893 | positive regulation of metabolic process | 51.3158 | 4 | yes |
| GO:0010468 | regulation of gene expression | 50.0000 | 6 | yes |
| GO:0010556 | regulation of macromolecule biosynthetic process | 50.0000 | 5 | yes |
| GO:0031326 | regulation of cellular biosynthetic process | 50.0000 | 5 | yes |
| GO:0010646 | regulation of cell communication | 48.6842 | 4 | no |
| GO:0010604 | positive regulation of macromolecule metabolic process | 47.3684 | 5 | yes |
| GO:0051246 | regulation of protein metabolic process | 47.3684 | 5 | yes |
| GO:0051128 | regulation of cellular component organization | 46.0526 | 4 | yes |
| GO:0009892 | negative regulation of metabolic process | 43.4211 | 4 | yes |
| GO:0019219 | regulation of nucleobase-containing compound metabolic process | 42.1053 | 5 | yes |
| GO:0031325 | positive regulation of cellular metabolic process | 42.1053 | 5 | no |
| GO:0010605 | negative regulation of macromolecule metabolic process | 40.7895 | 5 | yes |
| GO:0031324 | negative regulation of cellular metabolic process | 40.7895 | 5 | yes |
| GO:0051252 | regulation of RNA metabolic process | 40.7895 | 5 | yes |
| GO:0009966 | regulation of signal transduction | 40.7895 | 4 | no |
| GO:0006355 | regulation of DNA-templated transcription | 38.1579 | 7 | yes |
| GO:0036211 | protein modification process | 38.1579 | 4 | yes |
| GO:0043412 | macromolecule modification | 38.1579 | 4 | yes |
| GO:2001141 | regulation of RNA biosynthetic process | 38.1579 | 6 | yes |
| GO:0022607 | cellular component assembly | 38.1579 | 4 | no |
| GO:0009891 | positive regulation of biosynthetic process | 38.1579 | 5 | no |
| GO:0008104 | protein localization | 35.5263 | 4 | yes |
| GO:0051247 | positive regulation of protein metabolic process | 35.5263 | 6 | yes |
| GO:0031328 | positive regulation of cellular biosynthetic process | 35.5263 | 6 | no |
| GO:0043067 | regulation of programmed cell death | 35.5263 | 4 | no |
| GO:0009890 | negative regulation of biosynthetic process | 34.2105 | 5 | yes |
| GO:0010558 | negative regulation of macromolecule biosynthetic process | 34.2105 | 6 | yes |
| GO:0031327 | negative regulation of cellular biosynthetic process | 34.2105 | 6 | yes |
| GO:0010648 | negative regulation of cell communication | 34.2105 | 5 | no |
| GO:0023057 | negative regulation of signaling | 34.2105 | 4 | no |
| GO:0048585 | negative regulation of response to stimulus | 34.2105 | 4 | no |
| GO:0042981 | regulation of apoptotic process | 34.2105 | 5 | no |
| GO:0006996 | organelle organization | 34.2105 | 4 | no |
| GO:0009894 | regulation of catabolic process | 32.8947 | 4 | yes |
| GO:0051049 | regulation of transport | 32.8947 | 4 | yes |
| GO:0031399 | regulation of protein modification process | 32.8947 | 6 | no |
| GO:1902531 | regulation of intracellular signal transduction | 32.8947 | 5 | no |
| GO:0010557 | positive regulation of macromolecule biosynthetic process | 32.8947 | 6 | no |
| GO:0060341 | regulation of cellular localization | 31.5789 | 4 | yes |
| GO:0032880 | regulation of protein localization | 30.2632 | 5 | yes |
| GO:0009968 | negative regulation of signal transduction | 30.2632 | 5 | no |
| GO:0023056 | positive regulation of signaling | 30.2632 | 4 | no |
| GO:0044087 | regulation of cellular component biogenesis | 28.9474 | 4 | yes |
| GO:0010647 | positive regulation of cell communication | 28.9474 | 5 | no |
| GO:0043687 | post-translational protein modification | 27.6316 | 5 | yes |
| GO:0045934 | negative regulation of nucleobase-containing compound metabolic process | 27.6316 | 5 | yes |
| GO:0006357 | regulation of transcription by RNA polymerase II | 27.6316 | 8 | no |
| GO:0043933 | protein-containing complex organization | 27.6316 | 4 | no |
| GO:0071702 | organic substance transport | 27.6316 | 4 | no |
| GO:0071705 | nitrogen compound transport | 27.6316 | 4 | no |
| GO:0032446 | protein modification by small protein conjugation | 26.3158 | 7 | yes |
| GO:0051130 | positive regulation of cellular component organization | 26.3158 | 5 | yes |
| GO:0070647 | protein modification by small protein conjugation or removal | 26.3158 | 6 | yes |
| GO:0031401 | positive regulation of protein modification process | 26.3158 | 7 | no |
| GO:0019220 | regulation of phosphate metabolic process | 26.3158 | 6 | no |
| GO:0048584 | positive regulation of response to stimulus | 26.3158 | 4 | no |
| GO:0051174 | regulation of phosphorus metabolic process | 26.3158 | 5 | no |
| GO:0080134 | regulation of response to stress | 26.3158 | 4 | no |
| GO:0033043 | regulation of organelle organization | 26.3158 | 5 | no |
| GO:0051253 | negative regulation of RNA metabolic process | 25.0000 | 6 | yes |
| GO:0006508 | proteolysis | 25.0000 | 4 | no |
| GO:0043066 | negative regulation of apoptotic process | 25.0000 | 6 | no |
| GO:0043069 | negative regulation of programmed cell death | 25.0000 | 5 | no |
| GO:0045935 | positive regulation of nucleobase-containing compound metabolic process | 25.0000 | 5 | no |
| GO:0065003 | protein-containing complex assembly | 23.6842 | 5 | no |
| GO:0009967 | positive regulation of signal transduction | 23.6842 | 5 | no |
| GO:0030162 | regulation of proteolysis | 22.3684 | 6 | yes |
| GO:0051248 | negative regulation of protein metabolic process | 22.3684 | 6 | no |
| GO:0010628 | positive regulation of gene expression | 22.3684 | 7 | no |
| GO:0051254 | positive regulation of RNA metabolic process | 22.3684 | 6 | no |
| GO:0071310 | cellular response to organic substance | 22.3684 | 4 | no |
| GO:0018193 | peptidyl-amino acid modification | 21.0526 | 5 | yes |
| GO:0045892 | negative regulation of DNA-templated transcription | 21.0526 | 8 | yes |
| GO:1902679 | negative regulation of RNA biosynthetic process | 21.0526 | 7 | yes |
| GO:0010629 | negative regulation of gene expression | 21.0526 | 7 | no |
| GO:0001932 | regulation of protein phosphorylation | 21.0526 | 7 | no |
| GO:0042325 | regulation of phosphorylation | 21.0526 | 7 | no |
| GO:0045893 | positive regulation of DNA-templated transcription | 21.0526 | 8 | no |
| GO:1901701 | cellular response to oxygen-containing compound | 21.0526 | 4 | no |
| GO:1902680 | positive regulation of RNA biosynthetic process | 21.0526 | 7 | no |
| GO:0090304 | nucleic acid metabolic process | 19.7368 | 4 | yes |
| GO:0009896 | positive regulation of catabolic process | 18.4211 | 5 | yes |
| GO:0042176 | regulation of protein catabolic process | 18.4211 | 5 | yes |
| GO:0043254 | regulation of protein-containing complex assembly | 18.4211 | 5 | yes |
| GO:0044089 | positive regulation of cellular component biogenesis | 18.4211 | 5 | yes |
| GO:0070201 | regulation of establishment of protein localization | 18.4211 | 6 | yes |
| GO:0018205 | peptidyl-lysine modification | 17.1053 | 6 | yes |
| GO:0006974 | DNA damage response | 15.7895 | 4 | yes |
| GO:0016925 | protein sumoylation | 15.7895 | 7 | yes |
| GO:0045862 | positive regulation of proteolysis | 15.7895 | 7 | yes |
| GO:0051223 | regulation of protein transport | 15.7895 | 5 | yes |
| GO:0031334 | positive regulation of protein-containing complex assembly | 14.4737 | 6 | yes |
| GO:0032386 | regulation of intracellular transport | 14.4737 | 5 | yes |
| GO:0051051 | negative regulation of transport | 14.4737 | 4 | yes |
| GO:1903050 | regulation of proteolysis involved in protein catabolic process | 14.4737 | 7 | yes |
| GO:0006259 | DNA metabolic process | 13.1579 | 5 | yes |
| GO:0061136 | regulation of proteasomal protein catabolic process | 13.1579 | 6 | yes |
| GO:1903828 | negative regulation of protein localization | 13.1579 | 5 | yes |
| GO:2000058 | regulation of ubiquitin-dependent protein catabolic process | 13.1579 | 5 | yes |
| GO:0006281 | DNA repair | 11.8421 | 5 | yes |
| GO:0032434 | regulation of proteasomal ubiquitin-dependent protein catabolic process | 11.8421 | 6 | yes |
| GO:0033157 | regulation of intracellular protein transport | 11.8421 | 6 | yes |
| GO:1900180 | regulation of protein localization to nucleus | 11.8421 | 6 | yes |
| GO:0034762 | regulation of transmembrane transport | 10.5263 | 4 | yes |
| GO:0046822 | regulation of nucleocytoplasmic transport | 10.5263 | 6 | yes |
| GO:0051224 | negative regulation of protein transport | 10.5263 | 5 | yes |
| GO:1904950 | negative regulation of establishment of protein localization | 10.5263 | 6 | yes |
| GO:0010038 | response to metal ion | 9.2105 | 4 | yes |
| GO:0034765 | regulation of monoatomic ion transmembrane transport | 9.2105 | 5 | yes |
| GO:0043269 | regulation of monoatomic ion transport | 9.2105 | 5 | yes |
| GO:0045732 | positive regulation of protein catabolic process | 9.2105 | 6 | yes |
| GO:1901800 | positive regulation of proteasomal protein catabolic process | 9.2105 | 7 | yes |
| GO:1903052 | positive regulation of proteolysis involved in protein catabolic process | 9.2105 | 8 | yes |
| GO:0010959 | regulation of metal ion transport | 7.8947 | 6 | yes |
| GO:0022898 | regulation of transmembrane transporter activity | 7.8947 | 4 | yes |
| GO:0032436 | positive regulation of proteasomal ubiquitin-dependent protein catabolic process | 7.8947 | 7 | yes |
| GO:0050821 | protein stabilization | 7.8947 | 4 | yes |
| GO:0071241 | cellular response to inorganic substance | 7.8947 | 4 | yes |
| GO:0071248 | cellular response to metal ion | 7.8947 | 5 | yes |
| GO:1904062 | regulation of monoatomic cation transmembrane transport | 7.8947 | 6 | yes |
| GO:2000060 | positive regulation of ubiquitin-dependent protein catabolic process | 7.8947 | 6 | yes |
| GO:0032387 | negative regulation of intracellular transport | 6.5789 | 5 | yes |
| GO:0032412 | regulation of monoatomic ion transmembrane transporter activity | 6.5789 | 5 | yes |
| GO:0046823 | negative regulation of nucleocytoplasmic transport | 6.5789 | 6 | yes |
| GO:0051100 | negative regulation of binding | 6.5789 | 4 | yes |
| GO:0051101 | regulation of DNA binding | 6.5789 | 4 | yes |
| GO:0090317 | negative regulation of intracellular protein transport | 6.5789 | 6 | yes |
| GO:0032410 | negative regulation of transporter activity | 5.2632 | 4 | yes |
| GO:0034605 | cellular response to heat | 5.2632 | 4 | yes |
| GO:0042306 | regulation of protein import into nucleus | 5.2632 | 7 | yes |
| GO:1900181 | negative regulation of protein localization to nucleus | 5.2632 | 6 | yes |
| GO:2001257 | regulation of cation channel activity | 5.2632 | 6 | yes |
| GO:0032413 | negative regulation of ion transmembrane transporter activity | 3.9474 | 5 | yes |
| GO:0034763 | negative regulation of transmembrane transport | 3.9474 | 5 | yes |
| GO:0034766 | negative regulation of monoatomic ion transmembrane transport | 3.9474 | 6 | yes |
| GO:0042308 | negative regulation of protein import into nucleus | 3.9474 | 7 | yes |
| GO:0043266 | regulation of potassium ion transport | 3.9474 | 7 | yes |
| GO:0043271 | negative regulation of monoatomic ion transport | 3.9474 | 5 | yes |
| GO:0043392 | negative regulation of DNA binding | 3.9474 | 5 | yes |
| GO:0043433 | negative regulation of DNA-binding transcription factor activity | 3.9474 | 4 | yes |
| GO:1901016 | regulation of potassium ion transmembrane transporter activity | 3.9474 | 6 | yes |
| GO:1901379 | regulation of potassium ion transmembrane transport | 3.9474 | 7 | yes |
| GO:1904063 | negative regulation of cation transmembrane transport | 3.9474 | 7 | yes |
| GO:2001258 | negative regulation of cation channel activity | 3.9474 | 6 | yes |
| GO:0010621 | negative regulation of transcription by transcription factor localization | 2.6316 | 5 | yes |
| GO:0043267 | negative regulation of potassium ion transport | 2.6316 | 6 | yes |
| GO:0045759 | negative regulation of action potential | 2.6316 | 4 | yes |
| GO:0046686 | response to cadmium ion | 2.6316 | 5 | yes |
| GO:0071276 | cellular response to cadmium ion | 2.6316 | 6 | yes |
| GO:1901017 | negative regulation of potassium ion transmembrane transporter activity | 2.6316 | 6 | yes |
| GO:1901380 | negative regulation of potassium ion transmembrane transport | 2.6316 | 7 | yes |
| GO:1902259 | regulation of delayed rectifier potassium channel activity | 2.6316 | 7 | yes |
| GO:1902260 | negative regulation of delayed rectifier potassium channel activity | 2.6316 | 8 | yes |
| GO:1903817 | negative regulation of voltage-gated potassium channel activity | 2.6316 | 7 | yes |
Disease
No data found.
All partners
| Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
|---|---|---|---|---|
| RWDD3_HUMAN | [view interactions] | Low throughput | no | no |
| NFKB2_HUMAN | [view interactions] | Low throughput | no | yes |
| EGR1_HUMAN | [view interactions] | Low throughput | no | yes |
| CNR1_HUMAN | [view interactions] | Low throughput | no | yes |
| IF4E_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| PARP1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| PSIP1_HUMAN | [view interactions] | Low throughput | no | yes |
| HNRPK_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| SRBP1_HUMAN | [view interactions] | Low throughput | no | yes |
| NR2C1_HUMAN | [view interactions] | Low throughput | no | yes |
| IRF1_HUMAN | [view interactions] | Low throughput | no | yes |
| MDM2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| PAX6_HUMAN | [view interactions] | Low throughput | no | no |
| MECP2_HUMAN | [view interactions] | Low throughput | no | yes |
| SAE1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| SENP2_HUMAN | [view interactions] | Low throughput | no | yes |
| C8AP2_HUMAN | [view interactions] | Low throughput | no | no |
| TFCP2_HUMAN | [view interactions] | Low throughput | no | no |
| ZCH12_HUMAN | [view interactions] | Low throughput | no | yes |
| HSF1_HUMAN | [view interactions] | Low throughput | no | yes |
| EHD3_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| TNR1A_HUMAN | [view interactions] | Low throughput | no | yes |
| TYDP2_HUMAN | [view interactions] | Low throughput | no | no |
| TOPRS_HUMAN | [view interactions] | Low throughput | no | yes |
| RAD52_HUMAN | [view interactions] | Low throughput | no | no |
| TOP2B_HUMAN | [view interactions] | Low throughput | no | yes |
| SALL1_HUMAN | [view interactions] | Low throughput | no | yes |
| MX1_HUMAN | [view interactions] | Low throughput | no | yes |
| RS3_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| DYN1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| ZBT16_HUMAN | [view interactions] | Low throughput | no | yes |
| TOLIP_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| ETV6_HUMAN | [view interactions] | Low throughput | no | no |
| MCR_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| CASP2_HUMAN | [view interactions] | Low throughput | no | yes |
| IRF8_HUMAN | [view interactions] | Low throughput | no | no |
| EAA2_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| TRPS1_HUMAN | [view interactions] | Low throughput | no | no |
| PARK7_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| ATX3_HUMAN | [view interactions] | Low throughput | no | yes |
| GRM8_HUMAN | [view interactions] | Low throughput | no | no |
| ATX1_HUMAN | [view interactions] | Low throughput | no | yes |
| XPO1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| IL27B_HUMAN | [view interactions] | Low throughput | no | no |
| FAF1_HUMAN | [view interactions] | Low throughput | no | yes |
| SMAD4_HUMAN | [view interactions] | Low throughput | no | yes |
| CSEN_HUMAN | [view interactions] | Low throughput | no | no |
| VHL_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| GLP1R_HUMAN | [view interactions] | Low throughput | no | no |
| GCR_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| YAP1_HUMAN | [view interactions] | Low throughput | no | yes |
| RBBP7_HUMAN | [view interactions] | Low throughput | no | yes |
| BUB1B_HUMAN | [view interactions] | Low throughput | no | no |
| RN111_HUMAN | [view interactions] | Low throughput | no | yes |
| SIMC1_HUMAN | [view interactions] | Low throughput | no | yes |
| UIMC1_HUMAN | [view interactions] | Low throughput | no | no |
| MAFB_HUMAN | [view interactions] | Low throughput | no | yes |
| PGH2_HUMAN | [view interactions] | Low throughput | no | no |
| CEBPA_HUMAN | [view interactions] | Low throughput | no | yes |
| NR1H4_HUMAN | [view interactions] | Low throughput | no | no |
| UBC_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| PRKN_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| KLF5_HUMAN | [view interactions] | Low throughput | no | yes |
| SLX4_HUMAN | [view interactions] | Low throughput | no | yes |
| CALX_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| M3K5_HUMAN | [view interactions] | Low throughput | no | yes |
| PIAS1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| PIAS3_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| P73_HUMAN | [view interactions] | Low throughput | no | no |
| DNM3B_HUMAN | [view interactions] | Low throughput | no | yes |
| DAXX_HUMAN | [view interactions] | Low throughput | no | yes |
| PML_HUMAN | [view interactions] | Low throughput | no | yes |
| IKZF1_HUMAN | [view interactions] | Low throughput | no | no |
| IKZF3_HUMAN | [view interactions] | Low throughput | no | no |
| TDG_HUMAN | [view interactions] | Low throughput | no | yes |
| SUMO1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| TNR6_HUMAN | [view interactions] | Low throughput | no | no |
| PIAS2_HUMAN | [view interactions] | Low throughput | no | yes |
| SATB1_HUMAN | [view interactions] | Low throughput | no | yes |
| SP100_HUMAN | [view interactions] | Low throughput | no | no |
| SOX10_HUMAN | [view interactions] | Low throughput | no | yes |
| ELK1_HUMAN | [view interactions] | Low throughput | no | yes |
| NF1_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| SIN3A_HUMAN | [view interactions] | Low throughput | no | yes |
| RAGP1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| MBD1_HUMAN | [view interactions] | Low throughput | no | yes |
| PTN1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| PROX1_HUMAN | [view interactions] | Low throughput | no | no |
| HIF1A_HUMAN | [view interactions] | Low throughput | no | no |
| EPAS1_HUMAN | [view interactions] | Low throughput | no | no |
| PRDM1_HUMAN | [view interactions] | Low throughput | no | yes |
| ZBT46_HUMAN | [view interactions] | Low throughput | no | no |
| P63_HUMAN | [view interactions] | Low throughput | no | no |
| USPL1_HUMAN | [view interactions] | Low throughput | no | yes |
| ITF2_HUMAN | [view interactions] | Low throughput | no | yes |
| CAN2_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| CBP_HUMAN | [view interactions] | Low throughput | no | yes |
| RARA_HUMAN | [view interactions] | Low throughput | no | no |
| ANXA2_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| C1TC_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| RBP2_HUMAN | [view interactions] | Low throughput | no | yes |
| CAF1A_HUMAN | [view interactions] | Low throughput | no | yes |
| T22D3_HUMAN | [view interactions] | Low throughput | no | yes |
| UBC9_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| TRIM5_HUMAN | [view interactions] | Low throughput | no | yes |
| ATX7_HUMAN | [view interactions] | Low throughput | no | no |
| UBP25_HUMAN | [view interactions] | Low throughput | no | yes |
| ZN451_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| NPM_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| KPYM_HUMAN | [view interactions] | Low throughput | no | yes |
| LA_HUMAN | [view interactions] | Low throughput | no | yes |
| ZMYM3_HUMAN | [view interactions] | Low throughput | no | yes |
| MEF2A_HUMAN | [view interactions] | Low throughput | no | yes |
| PCNA_HUMAN | [view interactions] | Low throughput | no | no |
| TP53B_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| E2AK2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| GRIK2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| CBX5_HUMAN | [view interactions] | Low throughput | no | yes |
| ZBED1_HUMAN | [view interactions] | Low throughput | no | yes |
| SYUA_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| CYGB_HUMAN | [view interactions] | Low throughput | no | yes |
| ARRB2_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| CEBPB_HUMAN | [view interactions] | Low throughput | no | no |
| IFIH1_HUMAN | [view interactions] | Low throughput | no | yes |
| NCOR2_HUMAN | [view interactions] | Low throughput | no | yes |
| MITF_HUMAN | [view interactions] | Low throughput | no | no |
| SENP6_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| TFEB_HUMAN | [view interactions] | Low throughput | no | no |
| MTOR_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| TFE3_HUMAN | [view interactions] | Low throughput | no | yes |
| PLAL1_HUMAN | [view interactions] | Low throughput | no | no |
| SENP1_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| EGLN3_HUMAN | [view interactions] | Low throughput | no | no |
| BRCA1_HUMAN | [view interactions] | Low throughput | no | yes |
| CDK6_HUMAN | [view interactions] | Low throughput | no | yes |
| KCNK1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| KCNB1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| HIPK2_HUMAN | [view interactions] | Low throughput | no | yes |
| NF2L2_HUMAN | [view interactions] | Low throughput | no | yes |
| SAE2_HUMAN | [view interactions] | Low throughput | no | yes |
| FOXM1_HUMAN | [view interactions] | Low throughput | no | yes |
| MUL1_HUMAN | [view interactions] | Low throughput | no | no |
| MD1L1_HUMAN | [view interactions] | Low throughput | no | yes |
| ING2_HUMAN | [view interactions] | Low throughput | no | yes |
| JUN_HUMAN | [view interactions] | Low throughput | no | yes |
| MYB_HUMAN | [view interactions] | Low throughput | no | yes |
| RNF4_HUMAN | [view interactions] | Low throughput | no | yes |
| NEMO_HUMAN | [view interactions] | Low throughput | no | yes |
| ANDR_HUMAN | [view interactions] | Low throughput | no | no |
| KCNA5_HUMAN | [view interactions] | Low throughput | no | no |
| RAD51_HUMAN | [view interactions] | Low throughput | no | yes |
| P53_HUMAN | [view interactions] | Low throughput | no | no |
| CHD3_HUMAN | [view interactions] | Low throughput | no | yes |
| TIF1B_HUMAN | [view interactions] | Low throughput | no | yes |
| CBX4_HUMAN | [view interactions] | Low throughput | no | yes |
| DPP8_HUMAN | [view interactions] | Low throughput | no | yes |
| OGT1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| WDR33_HUMAN | [view interactions] | High throughput | no | yes |
| ZN687_HUMAN | [view interactions] | High throughput | no | yes |
| ARI3A_HUMAN | [view interactions] | High throughput | no | yes |
| CDC5L_HUMAN | [view interactions] | High throughput | no | yes |
| PEX2_HUMAN | [view interactions] | High throughput | no | yes |
| HGS_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FSBP_HUMAN | [view interactions] | High throughput | no | yes |
| HNRPC_HUMAN | [view interactions] | High throughput | no | yes |
| ATF2_HUMAN | [view interactions] | High throughput | no | yes |
| SOX2_HUMAN | [view interactions] | High throughput | no | yes |
| SUMO5_HUMAN | [view interactions] | High throughput | no | no |
| EDAD_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ZBT26_HUMAN | [view interactions] | High throughput | no | no |
| DEUP1_HUMAN | [view interactions] | High throughput | no | no |
| ZBTB6_HUMAN | [view interactions] | High throughput | no | no |
| DTX2_HUMAN | [view interactions] | High throughput | no | yes |
| MISSL_HUMAN | [view interactions] | High throughput | no | yes |
| F118B_HUMAN | [view interactions] | High throughput | no | yes |
| RHXF2_HUMAN | [view interactions] | High throughput | no | no |
| TRAF4_HUMAN | [view interactions] | High throughput | no | yes |
| CARD9_HUMAN | [view interactions] | High throughput | no | no |
| ZMYM5_HUMAN | [view interactions] | High throughput | no | yes |
| ARIP4_HUMAN | [view interactions] | High throughput | no | yes |
| AXIN1_HUMAN | [view interactions] | High throughput | no | yes |
| ZBTB2_HUMAN | [view interactions] | High throughput | no | yes |
| BTBD3_HUMAN | [view interactions] | High throughput | no | yes |
| PROP1_HUMAN | [view interactions] | High throughput | no | no |
| ZFP42_HUMAN | [view interactions] | High throughput | no | no |
| TRAF2_HUMAN | [view interactions] | High throughput | no | yes |
| TRAF5_HUMAN | [view interactions] | High throughput | no | yes |
| ZCHC7_HUMAN | [view interactions] | High throughput | no | yes |
| HD_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TOE1_HUMAN | [view interactions] | High throughput | no | yes |
| MFI_HUMAN | [view interactions] | High throughput | no | no |
| CCR2_HUMAN | [view interactions] | High throughput | no | yes |
| ESR1_HUMAN | [view interactions] | High throughput | no | no |
| RN167_HUMAN | [view interactions] | High throughput | no | yes |
| FMR1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DYRK2_HUMAN | [view interactions] | High throughput | no | yes |
| GLI2_HUMAN | [view interactions] | High throughput | no | yes |
| FHI2A_HUMAN | [view interactions] | High throughput | no | yes |
| CFTR_HUMAN | [view interactions] | High throughput | no | no |
| SMC5_HUMAN | [view interactions] | High throughput | no | yes |
| ERR1_HUMAN | [view interactions] | High throughput | no | yes |
| ERR3_HUMAN | [view interactions] | High throughput | no | yes |
| HIPK3_HUMAN | [view interactions] | High throughput | no | yes |
| ZMYM2_HUMAN | [view interactions] | High throughput | no | yes |
| ZHX1_HUMAN | [view interactions] | High throughput | no | no |
| BLM_HUMAN | [view interactions] | High throughput | no | yes |
| WRN_HUMAN | [view interactions] | High throughput | no | yes |
| PIAS4_HUMAN | [view interactions] | High throughput | no | yes |
| PHC1_HUMAN | [view interactions] | High throughput | no | yes |
| GMCL1_HUMAN | [view interactions] | High throughput | no | yes |
| FBF1_HUMAN | [view interactions] | High throughput | no | no |
| SPOP_HUMAN | [view interactions] | High throughput | no | no |
| TMIE_HUMAN | [view interactions] | High throughput | no | yes |
| 4ET_HUMAN | [view interactions] | High throughput | no | yes |
| PCBP2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SUMO3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KAT5_HUMAN | [view interactions] | High throughput | no | yes |
| TERA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CUL7_HUMAN | [view interactions] | High throughput | no | yes |
| OBSL1_HUMAN | [view interactions] | High throughput | no | yes |
| IF16_HUMAN | [view interactions] | High throughput | no | no |
| FOXA1_HUMAN | [view interactions] | High throughput | no | no |
| RN168_HUMAN | [view interactions] | High throughput | no | no |
| ARC_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| HDAC4_HUMAN | [view interactions] | High throughput | no | yes |
| ESR2_HUMAN | [view interactions] | High throughput | no | no |
| UBE3A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TCTP_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| H4_HUMAN | [view interactions] | High throughput | no | yes |
| PKHA4_HUMAN | [view interactions] | High throughput | no | yes |
| FACD2_HUMAN | [view interactions] | High throughput | no | no |
| KIF14_HUMAN | [view interactions] | High throughput | no | no |
| NUPR1_HUMAN | [view interactions] | High throughput | no | no |
| BRD4_HUMAN | [view interactions] | High throughput | no | yes |
| ZGPAT_HUMAN | [view interactions] | High throughput | no | no |
| DHX16_HUMAN | [view interactions] | High throughput | no | yes |
| SNIP1_HUMAN | [view interactions] | High throughput | no | no |
| ARK2N_HUMAN | [view interactions] | High throughput | no | yes |
| LSS_HUMAN | [view interactions] | High throughput | no | yes |
| SMRCD_HUMAN | [view interactions] | High throughput | no | yes |
| UBF1_HUMAN | [view interactions] | High throughput | no | yes |
| ZO2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RMXL1_HUMAN | [view interactions] | High throughput | no | yes |
| SCAF4_HUMAN | [view interactions] | High throughput | no | yes |
| PRC2A_HUMAN | [view interactions] | High throughput | no | yes |
| RBM27_HUMAN | [view interactions] | High throughput | no | yes |
| UTP11_HUMAN | [view interactions] | High throughput | no | yes |
| RRP36_HUMAN | [view interactions] | High throughput | no | yes |
| DDX46_HUMAN | [view interactions] | High throughput | no | yes |
| T2FB_HUMAN | [view interactions] | High throughput | no | yes |
| RP9_HUMAN | [view interactions] | High throughput | no | yes |
| BIRC3_HUMAN | [view interactions] | High throughput | no | no |
| ZO1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| BRD3_HUMAN | [view interactions] | High throughput | no | yes |
| WDR46_HUMAN | [view interactions] | High throughput | no | yes |
| CATIN_HUMAN | [view interactions] | High throughput | no | yes |
| SETX_HUMAN | [view interactions] | High throughput | no | yes |
| PDZ11_HUMAN | [view interactions] | High throughput | no | yes |
| CWC25_HUMAN | [view interactions] | High throughput | no | yes |
| PR38B_HUMAN | [view interactions] | High throughput | no | no |
| SNR27_HUMAN | [view interactions] | High throughput | no | yes |
| PAK2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| PR38A_HUMAN | [view interactions] | High throughput | no | no |
| CBX1_HUMAN | [view interactions] | High throughput | no | yes |
| IMA3_HUMAN | [view interactions] | High throughput | no | yes |
| MARE1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MIF_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NUMA1_HUMAN | [view interactions] | High throughput | no | yes |
| NTF2_HUMAN | [view interactions] | High throughput | no | yes |
| RAN_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RANG_HUMAN | [view interactions] | High throughput | no | no |
| SSRP1_HUMAN | [view interactions] | High throughput | no | yes |
| TLS1_HUMAN | [view interactions] | High throughput | no | yes |
| CUL3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ZRAN1_HUMAN | [view interactions] | High throughput | no | yes |
| ACE2_HUMAN | [view interactions] | High throughput | no | no |
| PARPT_HUMAN | [view interactions] | High throughput | no | no |
| NUP98_HUMAN | [view interactions] | High throughput | no | no |
| NU107_HUMAN | [view interactions] | High throughput | no | no |
| PSME3_HUMAN | [view interactions] | High throughput | no | yes |
| NU155_HUMAN | [view interactions] | High throughput | no | yes |
| UBE2H_HUMAN | [view interactions] | High throughput | no | yes |
| RCC1_HUMAN | [view interactions] | High throughput | no | yes |
| NU153_HUMAN | [view interactions] | High throughput | no | yes |
| SEH1_HUMAN | [view interactions] | High throughput | no | no |
| IMB1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ERCC6_HUMAN | [view interactions] | High throughput | no | no |
| MRE11_HUMAN | [view interactions] | High throughput | no | yes |
| XPO7_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KI67_HUMAN | [view interactions] | High throughput | no | no |
| ISG15_HUMAN | [view interactions] | High throughput | no | no |
| PPIL3_HUMAN | [view interactions] | High throughput | no | yes |
| PRDX5_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RN169_HUMAN | [view interactions] | High throughput | no | no |
| ST1A1_HUMAN | [view interactions] | High throughput | no | no |
| TANK_HUMAN | [view interactions] | High throughput | no | yes |
| ZNRD2_HUMAN | [view interactions] | High throughput | no | yes |
| TBK1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ARC1B_HUMAN | [view interactions] | High throughput | no | no |
| IKKE_HUMAN | [view interactions] | High throughput | no | yes |
| ARPC2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ARPC4_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| KAPCB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PFD2_HUMAN | [view interactions] | High throughput | no | yes |
| PSMD2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PABP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| BID_HUMAN | [view interactions] | High throughput | no | no |
| RFIP5_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| BCAM_HUMAN | [view interactions] | High throughput | no | yes |
| PLK1_HUMAN | [view interactions] | High throughput | no | yes |
| D2HDH_HUMAN | [view interactions] | High throughput | no | no |
| CHD8_HUMAN | [view interactions] | High throughput | no | no |
| SDF2L_HUMAN | [view interactions] | High throughput | no | yes |
| ZN106_HUMAN | [view interactions] | High throughput | no | no |
| DHX9_HUMAN | [view interactions] | High throughput | no | yes |
| STOM_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| EP300_HUMAN | [view interactions] | High throughput | no | yes |
| PPB1_HUMAN | [view interactions] | High throughput | no | no |
| SRC8_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DHX30_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AKAP9_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SNUT1_HUMAN | [view interactions] | High throughput | no | yes |
| HDAC6_HUMAN | [view interactions] | High throughput | no | yes |
| H2B2E_HUMAN | [view interactions] | High throughput | no | yes |
| EWS_HUMAN | [view interactions] | High throughput | no | yes |
| BEND3_HUMAN | [view interactions] | High throughput | no | yes |
| MIB1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| IN80B_HUMAN | [view interactions] | High throughput | no | no |
| GOGA1_HUMAN | [view interactions] | High throughput | no | yes |
| ARI5B_HUMAN | [view interactions] | High throughput | no | yes |
| NAA40_HUMAN | [view interactions] | High throughput | no | no |
| RED2_HUMAN | [view interactions] | High throughput | no | no |
| NBR1_HUMAN | [view interactions] | High throughput | no | yes |
| ZN768_HUMAN | [view interactions] | High throughput | no | yes |
| PHLP1_HUMAN | [view interactions] | High throughput | no | yes |
| RREB1_HUMAN | [view interactions] | High throughput | no | yes |
| MYC_HUMAN | [view interactions] | High throughput | no | yes |
| PAR12_HUMAN | [view interactions] | High throughput | no | yes |
| RFA1_HUMAN | [view interactions] | High throughput | no | yes |
| ZN317_HUMAN | [view interactions] | High throughput | no | yes |
| RFA4_HUMAN | [view interactions] | High throughput | no | yes |
| ZSC12_HUMAN | [view interactions] | High throughput | no | yes |
| F120C_HUMAN | [view interactions] | High throughput | no | yes |
| ZN362_HUMAN | [view interactions] | High throughput | no | no |
| SPTB2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CHD2_HUMAN | [view interactions] | High throughput | no | yes |
| RBAK_HUMAN | [view interactions] | High throughput | no | no |
| CENPV_HUMAN | [view interactions] | High throughput | no | yes |
| ZN592_HUMAN | [view interactions] | High throughput | no | yes |
| BCKD_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ZN174_HUMAN | [view interactions] | High throughput | no | yes |
| P5CS_HUMAN | [view interactions] | High throughput | no | yes |
| RSBN1_HUMAN | [view interactions] | High throughput | no | yes |
| PP1RA_HUMAN | [view interactions] | High throughput | no | yes |