KAPCB_HUMAN
Mediates cAMP-dependent signaling triggered by receptor binding to GPCRs. PKA activation regulates diverse cellular processes such as cell proliferation, the cell cycle, differentiation and regulation of microtubule dynamics, chromatin condensation and decondensation, nuclear envelope disassembly and reassembly, as well as regulation of intracellular transport mechanisms and ion flux. Regulates the abundance of compartmentalized pools of its regulatory subunits through phosphorylation of PJA2 which binds and ubiquitinates these subunits, leading to their subsequent proteolysis (PubMed, PubMed). Phosphorylates GPKOW which regulates its ability to bind RNA (PubMed). [View more on UniProt]
Interacting region for partners were not defined.
No data found.
No annotated instance was found. To search for linear motifs, use the ELM prediction server.
Molecular function
Term | Name | % | Distance from the top of the tree | Annotated in KAPCB_HUMAN |
---|---|---|---|---|
GO:0017076 | purine nucleotide binding | 37.7193 | 4 | yes |
GO:0032555 | purine ribonucleotide binding | 37.7193 | 4 | yes |
GO:0019900 | kinase binding | 32.4561 | 4 | no |
GO:0035639 | purine ribonucleoside triphosphate binding | 31.5789 | 4 | yes |
GO:0046872 | metal ion binding | 31.5789 | 4 | yes |
GO:0019901 | protein kinase binding | 31.5789 | 5 | no |
GO:0030554 | adenyl nucleotide binding | 29.8246 | 5 | yes |
GO:0032559 | adenyl ribonucleotide binding | 29.8246 | 5 | yes |
GO:0005524 | ATP binding | 24.5614 | 5 | yes |
GO:0016301 | kinase activity | 16.6667 | 4 | yes |
GO:0016773 | phosphotransferase activity, alcohol group as acceptor | 16.6667 | 4 | yes |
GO:0004712 | protein serine/threonine/tyrosine kinase activity | 15.7895 | 4 | yes |
GO:0004674 | protein serine/threonine kinase activity | 13.1579 | 4 | yes |
GO:0106310 | protein serine kinase activity | 13.1579 | 4 | yes |
GO:0031625 | ubiquitin protein ligase binding | 11.4035 | 5 | yes |
GO:0044389 | ubiquitin-like protein ligase binding | 11.4035 | 4 | yes |
GO:0000287 | magnesium ion binding | 2.6316 | 5 | yes |
GO:0004679 | AMP-activated protein kinase activity | 1.7544 | 5 | yes |
GO:0004690 | cyclic nucleotide-dependent protein kinase activity | 1.7544 | 5 | yes |
GO:0004691 | cAMP-dependent protein kinase activity | 1.7544 | 6 | yes |
Biological process
Term | Name | % | Distance from top the of the tree | Annotated in KAPCB_HUMAN |
---|---|---|---|---|
GO:0048522 | positive regulation of cellular process | 63.1579 | 4 | no |
GO:0010646 | regulation of cell communication | 59.6491 | 4 | yes |
GO:0060255 | regulation of macromolecule metabolic process | 57.0175 | 4 | yes |
GO:0048523 | negative regulation of cellular process | 55.2632 | 4 | yes |
GO:0051171 | regulation of nitrogen compound metabolic process | 55.2632 | 4 | yes |
GO:0080090 | regulation of primary metabolic process | 55.2632 | 4 | yes |
GO:0031323 | regulation of cellular metabolic process | 53.5088 | 4 | no |
GO:0009966 | regulation of signal transduction | 48.2456 | 4 | yes |
GO:0051246 | regulation of protein metabolic process | 48.2456 | 5 | yes |
GO:0051049 | regulation of transport | 44.7368 | 4 | no |
GO:0051128 | regulation of cellular component organization | 40.3509 | 4 | no |
GO:0010468 | regulation of gene expression | 39.4737 | 5 | yes |
GO:0022607 | cellular component assembly | 38.5965 | 4 | yes |
GO:0009893 | positive regulation of metabolic process | 38.5965 | 4 | no |
GO:0071310 | cellular response to organic substance | 37.7193 | 4 | no |
GO:1902531 | regulation of intracellular signal transduction | 35.9649 | 5 | no |
GO:0010604 | positive regulation of macromolecule metabolic process | 35.9649 | 5 | no |
GO:0010647 | positive regulation of cell communication | 35.9649 | 5 | no |
GO:0023056 | positive regulation of signaling | 35.9649 | 4 | no |
GO:0019220 | regulation of phosphate metabolic process | 35.0877 | 6 | no |
GO:0031399 | regulation of protein modification process | 35.0877 | 6 | no |
GO:0051173 | positive regulation of nitrogen compound metabolic process | 35.0877 | 5 | no |
GO:0051174 | regulation of phosphorus metabolic process | 35.0877 | 5 | no |
GO:0010243 | response to organonitrogen compound | 34.2105 | 4 | no |
GO:1901701 | cellular response to oxygen-containing compound | 34.2105 | 4 | no |
GO:0010941 | regulation of cell death | 32.4561 | 4 | no |
GO:0060341 | regulation of cellular localization | 32.4561 | 4 | no |
GO:0009889 | regulation of biosynthetic process | 32.4561 | 4 | no |
GO:0031325 | positive regulation of cellular metabolic process | 32.4561 | 5 | no |
GO:0031326 | regulation of cellular biosynthetic process | 32.4561 | 5 | no |
GO:0042325 | regulation of phosphorylation | 32.4561 | 7 | no |
GO:0048584 | positive regulation of response to stimulus | 32.4561 | 4 | no |
GO:0006996 | organelle organization | 31.5789 | 4 | no |
GO:0010556 | regulation of macromolecule biosynthetic process | 31.5789 | 5 | no |
GO:0051247 | positive regulation of protein metabolic process | 31.5789 | 6 | no |
GO:0009892 | negative regulation of metabolic process | 30.7018 | 4 | no |
GO:0006796 | phosphate-containing compound metabolic process | 29.8246 | 4 | yes |
GO:0042981 | regulation of apoptotic process | 29.8246 | 6 | no |
GO:0043067 | regulation of programmed cell death | 29.8246 | 5 | no |
GO:0001932 | regulation of protein phosphorylation | 29.8246 | 7 | no |
GO:0043085 | positive regulation of catalytic activity | 28.9474 | 4 | no |
GO:0008104 | protein localization | 28.9474 | 4 | no |
GO:0036211 | protein modification process | 28.0702 | 4 | yes |
GO:0043412 | macromolecule modification | 28.0702 | 4 | yes |
GO:0032880 | regulation of protein localization | 28.0702 | 5 | no |
GO:0050804 | modulation of chemical synaptic transmission | 28.0702 | 5 | no |
GO:0099177 | regulation of trans-synaptic signaling | 28.0702 | 4 | no |
GO:0009967 | positive regulation of signal transduction | 28.0702 | 5 | no |
GO:0010605 | negative regulation of macromolecule metabolic process | 28.0702 | 5 | no |
GO:0019219 | regulation of nucleobase-containing compound metabolic process | 28.0702 | 5 | no |
GO:1901699 | cellular response to nitrogen compound | 27.1930 | 4 | no |
GO:0030030 | cell projection organization | 27.1930 | 4 | no |
GO:0051172 | negative regulation of nitrogen compound metabolic process | 27.1930 | 5 | no |
GO:0051338 | regulation of transferase activity | 26.3158 | 4 | no |
GO:0051252 | regulation of RNA metabolic process | 25.4386 | 5 | no |
GO:1903506 | regulation of nucleic acid-templated transcription | 25.4386 | 7 | no |
GO:2001141 | regulation of RNA biosynthetic process | 25.4386 | 6 | no |
GO:0014070 | response to organic cyclic compound | 25.4386 | 4 | no |
GO:0071417 | cellular response to organonitrogen compound | 25.4386 | 4 | no |
GO:0010648 | negative regulation of cell communication | 25.4386 | 5 | yes |
GO:0023057 | negative regulation of signaling | 25.4386 | 4 | yes |
GO:0051050 | positive regulation of transport | 25.4386 | 4 | no |
GO:0006355 | regulation of DNA-templated transcription | 25.4386 | 6 | no |
GO:0031324 | negative regulation of cellular metabolic process | 25.4386 | 5 | no |
GO:0080134 | regulation of response to stress | 24.5614 | 4 | no |
GO:0043933 | protein-containing complex organization | 24.5614 | 4 | yes |
GO:0051130 | positive regulation of cellular component organization | 24.5614 | 5 | no |
GO:0120036 | plasma membrane bounded cell projection organization | 23.6842 | 5 | no |
GO:1902533 | positive regulation of intracellular signal transduction | 23.6842 | 6 | no |
GO:0033043 | regulation of organelle organization | 23.6842 | 5 | no |
GO:0010562 | positive regulation of phosphorus metabolic process | 22.8070 | 6 | no |
GO:0045937 | positive regulation of phosphate metabolic process | 22.8070 | 7 | no |
GO:0051240 | positive regulation of multicellular organismal process | 22.8070 | 4 | no |
GO:0043549 | regulation of kinase activity | 22.8070 | 5 | no |
GO:0051248 | negative regulation of protein metabolic process | 22.8070 | 6 | no |
GO:0031401 | positive regulation of protein modification process | 21.9298 | 7 | no |
GO:0042327 | positive regulation of phosphorylation | 21.9298 | 8 | no |
GO:0051094 | positive regulation of developmental process | 21.9298 | 4 | no |
GO:0065003 | protein-containing complex assembly | 21.9298 | 5 | yes |
GO:0045595 | regulation of cell differentiation | 21.0526 | 4 | no |
GO:0071407 | cellular response to organic cyclic compound | 21.0526 | 5 | no |
GO:0060548 | negative regulation of cell death | 21.0526 | 5 | no |
GO:0048585 | negative regulation of response to stimulus | 21.0526 | 4 | yes |
GO:0043269 | regulation of ion transport | 21.0526 | 5 | no |
GO:0042127 | regulation of cell population proliferation | 21.0526 | 4 | no |
GO:0044087 | regulation of cellular component biogenesis | 21.0526 | 4 | no |
GO:0045859 | regulation of protein kinase activity | 21.0526 | 6 | no |
GO:0001934 | positive regulation of protein phosphorylation | 20.1754 | 8 | no |
GO:0009894 | regulation of catabolic process | 20.1754 | 4 | no |
GO:0071702 | organic substance transport | 20.1754 | 4 | no |
GO:0022603 | regulation of anatomical structure morphogenesis | 20.1754 | 4 | no |
GO:0016192 | vesicle-mediated transport | 20.1754 | 4 | no |
GO:0006468 | protein phosphorylation | 20.1754 | 5 | yes |
GO:0016310 | phosphorylation | 20.1754 | 5 | yes |
GO:0034762 | regulation of transmembrane transport | 20.1754 | 4 | no |
GO:1903829 | positive regulation of protein localization | 20.1754 | 5 | no |
GO:0009968 | negative regulation of signal transduction | 19.2982 | 5 | yes |
GO:0030162 | regulation of proteolysis | 17.5439 | 6 | yes |
GO:0048878 | chemical homeostasis | 16.6667 | 4 | yes |
GO:0007188 | adenylate cyclase-modulating G protein-coupled receptor signaling pathway | 8.7719 | 4 | yes |
GO:0010737 | protein kinase A signaling | 3.5088 | 4 | yes |
GO:0001843 | neural tube closure | 1.7544 | 5 | yes |
GO:0003091 | renal water homeostasis | 1.7544 | 4 | yes |
GO:0008589 | regulation of smoothened signaling pathway | 1.7544 | 5 | yes |
GO:0030104 | water homeostasis | 1.7544 | 5 | yes |
GO:0034380 | high-density lipoprotein particle assembly | 1.7544 | 4 | yes |
GO:0045879 | negative regulation of smoothened signaling pathway | 1.7544 | 6 | yes |
GO:0060606 | tube closure | 1.7544 | 4 | yes |
GO:0065005 | protein-lipid complex assembly | 1.7544 | 6 | yes |
GO:0070613 | regulation of protein processing | 1.7544 | 7 | yes |
GO:0071825 | protein-lipid complex subunit organization | 1.7544 | 5 | yes |
GO:1901620 | regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning | 1.7544 | 6 | yes |
GO:1901621 | negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning | 1.7544 | 7 | yes |
GO:1903317 | regulation of protein maturation | 1.7544 | 6 | yes |
Disease
Term | Name | % | Distance from top the of the tree | Annotated in KAPCB_HUMAN |
---|---|---|---|---|
DOID:114 | heart disease | 4.3860 | 3 | no |
DOID:0050700 | cardiomyopathy | 3.5088 | 4 | no |
DOID:0060036 | intrinsic cardiomyopathy | 3.5088 | 5 | no |
DOID:331 | central nervous system disease | 1.7544 | 3 | no |
DOID:0080001 | bone disease | 1.7544 | 4 | no |
DOID:0080006 | bone development disease | 1.7544 | 5 | no |
DOID:65 | connective tissue disease | 1.7544 | 3 | no |
DOID:12930 | dilated cardiomyopathy | 1.7544 | 6 | no |
Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
---|---|---|---|---|
KAP0_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
FLNA_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
RCAN1_HUMAN | [view interactions] | Low throughput | no | yes |
TNR16_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
P73_HUMAN | [view interactions] | Low throughput | no | no |
MAVS_HUMAN | [view interactions] | Low throughput | no | yes |
TRAF6_HUMAN | [view interactions] | Low throughput | no | yes |
TRAF3_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
RN216_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
RYR2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
STP1_HUMAN | [view interactions] | Low throughput | no | no |
STP2_HUMAN | [view interactions] | Low throughput | no | no |
GLUT4_HUMAN | [view interactions] | High throughput | no | no |
IQCB1_HUMAN | [view interactions] | High throughput | no | no |
CEP43_HUMAN | [view interactions] | High throughput | no | no |
C170L_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
AKAP5_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
GSK3B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
DYL1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
SMN_HUMAN | [view interactions] | High throughput | no | yes |
CK5P2_HUMAN | [view interactions] | High throughput | no | yes |
KAPCA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
CCD77_HUMAN | [view interactions] | High throughput | no | yes |
CSPP1_HUMAN | [view interactions] | High throughput | no | no |
PCM1_HUMAN | [view interactions] | High throughput | no | yes |
KAP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
MYOME_HUMAN | [view interactions] | High throughput | no | no |
CE170_HUMAN | [view interactions] | High throughput | no | yes |
OFD1_HUMAN | [view interactions] | High throughput | no | yes |
PCNT_HUMAN | [view interactions] | High throughput | no | yes |
AKA11_HUMAN | [view interactions] | High throughput | no | yes |
CEP72_HUMAN | [view interactions] | High throughput | no | yes |
MOONR_HUMAN | [view interactions] | High throughput | no | yes |
MARE1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
GOGA3_HUMAN | [view interactions] | High throughput | no | yes |
AKAP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
CEP68_HUMAN | [view interactions] | High throughput | no | yes |
PRKX_HUMAN | [view interactions] | High throughput | no | yes |
KAP2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
CALX_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
FGOP2_HUMAN | [view interactions] | High throughput | no | yes |
SCO2_HUMAN | [view interactions] | High throughput | no | no |
VAPB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
KAP3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
USO1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
SOCS1_HUMAN | [view interactions] | High throughput | no | yes |
BAD_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
KPCZ_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
KPCI_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
FYN_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
H2B1H_HUMAN | [view interactions] | High throughput | no | yes |
TAU_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
HMGA2_HUMAN | [view interactions] | High throughput | no | yes |
XPO1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
NUAK1_HUMAN | [view interactions] | High throughput | no | no |
MYH4_HUMAN | [view interactions] | High throughput | no | no |
AKAP2_HUMAN | [view interactions] | High throughput | no | no |
IPKG_HUMAN | [view interactions] | High throughput | no | yes |
MYH2_HUMAN | [view interactions] | High throughput | no | yes |
AKA7G_HUMAN | [view interactions] | High throughput | no | yes |
VAPA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
SMAKA_HUMAN | [view interactions] | High throughput | no | yes |
AKAP9_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
DDX11_HUMAN | [view interactions] | High throughput | no | yes |
GP161_HUMAN | [view interactions] | High throughput | no | yes |
DYR1A_HUMAN | [view interactions] | High throughput | no | yes |
MYH6_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
MYH1_HUMAN | [view interactions] | High throughput | no | no |
MYL1_HUMAN | [view interactions] | High throughput | no | no |
CNKR2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
TNIK_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
DLG4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
ANS1B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
CSK21_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
RL27A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
RS6_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
ARFG1_HUMAN | [view interactions] | High throughput | no | no |
ACV1B_HUMAN | [view interactions] | High throughput | no | no |
APBP2_HUMAN | [view interactions] | High throughput | no | yes |
AVPI1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
IPKA_HUMAN | [view interactions] | High throughput | no | yes |
A4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
HS90A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
HS90B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
DCAF7_HUMAN | [view interactions] | High throughput | no | yes |
TRAP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
PITX2_HUMAN | [view interactions] | High throughput | no | no |
PEBB_HUMAN | [view interactions] | High throughput | no | no |
OSTP_HUMAN | [view interactions] | High throughput | no | yes |
1433Z_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
MLF1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
SNAG_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
PER1_HUMAN | [view interactions] | High throughput | no | no |
TALDO_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
PGTB2_HUMAN | [view interactions] | High throughput | no | yes |
CK049_HUMAN | [view interactions] | High throughput | no | yes |
AP2M1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
DCR1C_HUMAN | [view interactions] | High throughput | no | no |
CCNL2_HUMAN | [view interactions] | High throughput | no | yes |
AKA28_HUMAN | [view interactions] | High throughput | no | no |
NTRK1_HUMAN | [view interactions] | High throughput | no | yes |
PKP4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
AKP13_HUMAN | [view interactions] | High throughput | no | yes |
CP131_HUMAN | [view interactions] | High throughput | no | no |
TBC31_HUMAN | [view interactions] | High throughput | no | yes |
KAPCG_HUMAN | [view interactions] | High throughput | no | no |
FKBP5_HUMAN | [view interactions] | High throughput | no | yes |
BMP1_HUMAN | [view interactions] | High throughput | no | yes |
RT15_HUMAN | [view interactions] | High throughput | no | yes |
ETFB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
NPAS1_HUMAN | [view interactions] | High throughput | no | no |
DFFB_HUMAN | [view interactions] | High throughput | no | yes |
RPGF5_HUMAN | [view interactions] | High throughput | no | yes |
KLH28_HUMAN | [view interactions] | High throughput | no | no |
DNA2_HUMAN | [view interactions] | High throughput | no | yes |
AGAP2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
FACD2_HUMAN | [view interactions] | High throughput | no | no |
TRI25_HUMAN | [view interactions] | High throughput | no | yes |
HNRPL_HUMAN | [view interactions] | High throughput | no | yes |
RECQ4_HUMAN | [view interactions] | High throughput | no | yes |
NEB2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
ATX1_HUMAN | [view interactions] | High throughput | no | yes |
TIA1_HUMAN | [view interactions] | High throughput | no | no |
PKHA4_HUMAN | [view interactions] | High throughput | no | yes |
RHG36_HUMAN | [view interactions] | High throughput | no | yes |
HPT_HUMAN | [view interactions] | High throughput | no | no |
TRFE_HUMAN | [view interactions] | High throughput | no | no |
FIBG_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
H12_HUMAN | [view interactions] | High throughput | no | yes |
DX39A_HUMAN | [view interactions] | High throughput | no | yes |
MAP10_HUMAN | [view interactions] | High throughput | no | no |
DUS16_HUMAN | [view interactions] | High throughput | no | yes |
NAA11_HUMAN | [view interactions] | High throughput | no | no |
DYL2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
CCD96_HUMAN | [view interactions] | High throughput | no | no |
TIMP3_HUMAN | [view interactions] | High throughput | no | no |
CR3L3_HUMAN | [view interactions] | High throughput | no | no |
PICK1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
FGF14_HUMAN | [view interactions] | High throughput | no | no |
MTAP2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
RA51B_HUMAN | [view interactions] | High throughput | no | yes |
KCNE3_HUMAN | [view interactions] | High throughput | no | yes |
GSK3A_HUMAN | [view interactions] | High throughput | no | yes |
SULF2_HUMAN | [view interactions] | High throughput | no | yes |
ZN641_HUMAN | [view interactions] | High throughput | no | yes |
CEP57_HUMAN | [view interactions] | High throughput | no | yes |
CARF_HUMAN | [view interactions] | High throughput | no | yes |
FGD5_HUMAN | [view interactions] | High throughput | no | yes |
COR1A_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
RAC2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
FBX7_HUMAN | [view interactions] | High throughput | no | yes |
KBP_HUMAN | [view interactions] | High throughput | no | yes |
ARP2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
ARP3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
ARC1B_HUMAN | [view interactions] | High throughput | no | no |
ARPC2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
ARPC4_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
PFD1_HUMAN | [view interactions] | High throughput | no | yes |
SUMO1_HUMAN | [view interactions] | High throughput | no | yes |
PRPK_HUMAN | [view interactions] | High throughput | no | yes |
TPRKB_HUMAN | [view interactions] | High throughput | no | yes |
ARF1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
RPE_HUMAN | [view interactions] | High throughput | no | yes |
FAF2_HUMAN | [view interactions] | High throughput | no | yes |
TBC17_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
NIN_HUMAN | [view interactions] | High throughput | no | no |
ADCY8_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
ESR1_HUMAN | [view interactions] | Computational | no | no |
TTF1_HUMAN | [view interactions] | Computational | no | yes |
ADCY6_HUMAN | [view interactions] | Computational | no | yes |
KDM3A_HUMAN | [view interactions] | Computational | no | no |
ADCY7_HUMAN | [view interactions] | Computational | no | yes |
ANGT_HUMAN | [view interactions] | Computational | no | no |
ADRB2_HUMAN | [view entry] [view interactions] | Computational | yes | no |
KS6B1_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
CDK1_HUMAN | [view interactions] | Computational | no | no |
PRGR_HUMAN | [view interactions] | Computational | no | no |
IL3RB_HUMAN | [view interactions] | Computational | no | no |
MLC1_HUMAN | [view interactions] | Computational | no | no |
BCL2_HUMAN | [view interactions] | Computational | no | no |
GRIA1_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
NHRF1_HUMAN | [view interactions] | Computational | no | no |
CD2_HUMAN | [view interactions] | Computational | no | no |
RHOC_HUMAN | [view interactions] | Computational | no | no |
AKAP4_HUMAN | [view interactions] | Computational | no | no |
GYS2_HUMAN | [view interactions] | Computational | no | no |
ATF4_HUMAN | [view interactions] | Computational | no | no |
RUNX2_HUMAN | [view interactions] | Computational | no | no |
JUN_HUMAN | [view interactions] | Computational | no | yes |
NAC2_HUMAN | [view entry] [view interactions] | Computational | yes | no |
GFRA4_HUMAN | [view interactions] | Computational | no | no |
NAC1_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
SIK2_HUMAN | [view interactions] | Computational | no | yes |
NOS1_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
NCOA3_HUMAN | [view interactions] | Computational | no | yes |
NCK2_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
MPIP3_HUMAN | [view interactions] | Computational | no | yes |
NMDE1_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
SOX9_HUMAN | [view interactions] | Computational | no | no |
GBB1_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
TNNI3_HUMAN | [view interactions] | Computational | no | no |
BAX_HUMAN | [view interactions] | Computational | no | yes |
CSF2R_HUMAN | [view interactions] | Computational | no | no |
ANDR_HUMAN | [view interactions] | Computational | no | no |
MK03_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
TTF2_HUMAN | [view interactions] | Computational | no | yes |
GDIR1_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
PSN1_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
RPGP2_HUMAN | [view interactions] | Computational | no | yes |
RAP1B_HUMAN | [view entry] [view interactions] | Computational | yes | no |
S12A2_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
PDE4D_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
ABCC8_HUMAN | [view interactions] | Computational | no | yes |
AQP2_HUMAN | [view interactions] | Computational | no | no |
GFRA2_HUMAN | [view interactions] | Computational | no | yes |
PDE4A_HUMAN | [view interactions] | Computational | no | no |
GDIR2_HUMAN | [view interactions] | Computational | no | no |
FAK1_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
KCNS3_HUMAN | [view interactions] | Computational | no | yes |
PPARA_HUMAN | [view interactions] | Computational | no | yes |
TLN1_HUMAN | [view entry] [view interactions] | Computational | yes | no |
KCNC2_HUMAN | [view entry] [view interactions] | Computational | yes | no |
PPR1B_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
NPY4R_HUMAN | [view interactions] | Computational | no | yes |
2A5D_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
F262_HUMAN | [view interactions] | Computational | no | no |
RAF1_HUMAN | [view entry] [view interactions] | Computational | yes | no |
ADCY1_HUMAN | [view entry] [view interactions] | Computational | yes | no |
CAC1D_HUMAN | [view interactions] | Computational | no | yes |
JAK2_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
GDNF_HUMAN | [view interactions] | Computational | no | yes |
GBG1_HUMAN | [view interactions] | Computational | no | no |
CAC1C_HUMAN | [view entry] [view interactions] | Computational | yes | no |
TRPV1_HUMAN | [view entry] [view interactions] | Computational | yes | no |
CTNB1_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
KCMA1_HUMAN | [view entry] [view interactions] | Computational | yes | no |
PLIN1_HUMAN | [view interactions] | Computational | no | no |
CREB1_HUMAN | [view interactions] | Computational | no | yes |
KCNE1_HUMAN | [view interactions] | Computational | no | no |
CARM1_HUMAN | [view interactions] | Computational | no | yes |
TF65_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
NFKB1_HUMAN | [view interactions] | Computational | no | yes |
ITA4_HUMAN | [view interactions] | Computational | no | no |
KCNB1_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
ADCY3_HUMAN | [view interactions] | Computational | no | yes |
MED1_HUMAN | [view interactions] | Computational | no | no |
NMDE2_HUMAN | [view entry] [view interactions] | Computational | yes | no |
SUFU_HUMAN | [view interactions] | Computational | no | yes |
ADCYA_HUMAN | [view interactions] | Computational | no | yes |
FOXO1_HUMAN | [view interactions] | Computational | no | yes |
PDX1_HUMAN | [view interactions] | Computational | no | no |
FOS_HUMAN | [view interactions] | Computational | no | yes |
AKAP8_HUMAN | [view interactions] | Computational | no | yes |
CCL11_HUMAN | [view interactions] | Computational | no | no |
GBRAP_HUMAN | [view interactions] | Computational | no | no |
AAPK2_HUMAN | [view interactions] | Computational | no | yes |
IKBA_HUMAN | [view interactions] | Computational | no | yes |
PP1R8_HUMAN | [view interactions] | Computational | no | yes |
EZRI_HUMAN | [view entry] [view interactions] | Computational | yes | no |
RET_HUMAN | [view interactions] | Computational | no | yes |
NCK1_HUMAN | [view interactions] | Computational | no | yes |
GLI1_HUMAN | [view interactions] | Computational | no | no |
STMN1_HUMAN | [view interactions] | Computational | no | yes |
RAB13_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
PP1A_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
M3K5_HUMAN | [view interactions] | Computational | no | yes |
GDIR3_HUMAN | [view interactions] | Computational | no | no |
KCNG2_HUMAN | [view interactions] | Computational | no | no |
KPYM_HUMAN | [view interactions] | Computational | no | yes |
MK01_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
AAPK1_HUMAN | [view interactions] | Computational | no | no |
STF1_HUMAN | [view interactions] | Computational | no | no |
ADCY2_HUMAN | [view interactions] | Computational | no | yes |
MP2K2_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
KDM3B_HUMAN | [view interactions] | Computational | no | yes |
VGFR2_HUMAN | [view interactions] | Computational | no | no |
RGRF2_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
FOXO3_HUMAN | [view interactions] | Computational | no | yes |
THRB_HUMAN | [view interactions] | Computational | no | no |
PDE5A_HUMAN | [view interactions] | Computational | no | yes |
PDE4B_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
CREM_HUMAN | [view interactions] | Computational | no | no |
NGF_HUMAN | [view interactions] | Computational | no | no |
CSF2_HUMAN | [view interactions] | Computational | no | no |
CD3Z_HUMAN | [view interactions] | Computational | no | no |
ITPR3_HUMAN | [view interactions] | Computational | no | yes |
ULK2_HUMAN | [view interactions] | Computational | no | yes |
AKTS1_HUMAN | [view interactions] | Computational | no | yes |
GBRL1_HUMAN | [view interactions] | Computational | no | yes |
PBX1_HUMAN | [view interactions] | Computational | no | yes |
ESR2_HUMAN | [view interactions] | Computational | no | no |
SDF1_HUMAN | [view interactions] | Computational | no | no |
RHOA_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
GLI3_HUMAN | [view interactions] | Computational | no | yes |
PLM_HUMAN | [view interactions] | Computational | no | no |
PAX8_HUMAN | [view interactions] | Computational | no | yes |
IL3_HUMAN | [view interactions] | Computational | no | no |
ITB1_HUMAN | [view entry] [view interactions] | Computational | yes | no |
MLXPL_HUMAN | [view interactions] | Computational | no | no |
GLI2_HUMAN | [view interactions] | Computational | no | yes |
ABCA1_HUMAN | [view interactions] | Computational | no | yes |
CCL4_HUMAN | [view interactions] | Computational | no | no |
RHOB_HUMAN | [view entry] [view interactions] | Computational | yes | no |
GCR_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
KS6B2_HUMAN | [view interactions] | Computational | no | yes |
CSK_HUMAN | [view interactions] | Computational | no | yes |
PAXI_HUMAN | [view interactions] | Computational | no | yes |
PSPN_HUMAN | [view interactions] | Computational | no | no |
GNAS1_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
NAC3_HUMAN | [view entry] [view interactions] | Computational | yes | no |
ITA1_HUMAN | [view interactions] | Computational | no | yes |
MP2K1_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
VASP_HUMAN | [view interactions] | Computational | no | yes |
KPCE_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
CFTR_HUMAN | [view interactions] | Computational | no | no |
KCNQ1_HUMAN | [view interactions] | Computational | no | yes |
MAPK5_HUMAN | [view interactions] | Computational | no | yes |
SP1_HUMAN | [view interactions] | Computational | no | yes |
EDN1_HUMAN | [view interactions] | Computational | no | no |
AAKG1_HUMAN | [view interactions] | Computational | no | no |
SCN1A_HUMAN | [view interactions] | Computational | no | no |
LIPS_HUMAN | [view entry] [view interactions] | Computational | yes | no |
SMO_HUMAN | [view interactions] | Computational | no | yes |
IL3RA_HUMAN | [view interactions] | Computational | no | yes |
ADCY9_HUMAN | [view interactions] | Computational | no | yes |
KCJ11_HUMAN | [view interactions] | Computational | no | no |
GRIA2_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
PDE11_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
CCNB1_HUMAN | [view interactions] | Computational | no | no |
B2CL1_HUMAN | [view interactions] | Computational | no | yes |
ITPR2_HUMAN | [view interactions] | Computational | no | yes |
SL9A1_HUMAN | [view interactions] | Computational | no | no |
RAP1A_HUMAN | [view entry] [view interactions] | Computational | yes | no |
GBRL2_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
F261_HUMAN | [view interactions] | Computational | no | no |
CND1_HUMAN | [view interactions] | Computational | no | yes |
ITA2_HUMAN | [view interactions] | Computational | no | yes |
GYS1_HUMAN | [view interactions] | Computational | no | yes |
GFRA3_HUMAN | [view interactions] | Computational | no | yes |
PPR1A_HUMAN | [view interactions] | Computational | no | yes |
RGRF1_HUMAN | [view interactions] | Computational | no | yes |
NFAC1_HUMAN | [view interactions] | Computational | no | no |
PPLA_HUMAN | [view interactions] | Computational | no | no |
ARTN_HUMAN | [view interactions] | Computational | no | no |
KCNK2_HUMAN | [view interactions] | Computational | no | no |
GFRA1_HUMAN | [view interactions] | Computational | no | no |
NRTN_HUMAN | [view interactions] | Computational | no | no |
ULK1_HUMAN | [view interactions] | Computational | no | no |
PKN1_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
FINC_HUMAN | [view interactions] | Computational | no | yes |