Features Interactions Isoform Disease Linear motifs Fingerprint Network All partners

USO1_HUMAN

General vesicular transport factor required for intercisternal transport in the Golgi stack; it is required for transcytotic fusion and/or subsequent binding of the vesicles to the target membrane. May well act as a vesicular anchor by interacting with the target membrane and holding the vesicular and target membranes in proximity. [View more on UniProt]

Interacting region for partners were not defined.

Download full PS network for entry.

No data found.

No annotated instance was found. To search for linear motifs, use the ELM prediction server.

Molecular function

Term Name % Distance from the top of the tree Annotated in USO1_HUMAN
GO:0017076 purine nucleotide binding 29.4118 4 no
GO:0032555 purine ribonucleotide binding 28.2353 4 no
GO:0035639 purine ribonucleoside triphosphate binding 25.8824 4 no
GO:0046872 metal ion binding 23.5294 4 no
GO:0030554 adenyl nucleotide binding 21.1765 5 no
GO:0003723 RNA binding 12.9412 4 yes
GO:0045296 cadherin binding 11.7647 4 yes

Biological process

Term Name % Distance from top the of the tree Annotated in USO1_HUMAN
GO:0008104 protein localization 48.2353 4 yes
GO:0048522 positive regulation of cellular process 44.7059 4 no
GO:0048523 negative regulation of cellular process 43.5294 4 no
GO:0051128 regulation of cellular component organization 41.1765 4 no
GO:0060255 regulation of macromolecule metabolic process 38.8235 4 no
GO:0080090 regulation of primary metabolic process 38.8235 4 no
GO:0051171 regulation of nitrogen compound metabolic process 37.6471 4 no
GO:0016192 vesicle-mediated transport 36.4706 4 yes
GO:0031323 regulation of cellular metabolic process 36.4706 4 no
GO:0006996 organelle organization 35.2941 4 yes
GO:0071702 organic substance transport 35.2941 4 yes
GO:0071705 nitrogen compound transport 35.2941 4 yes
GO:0015031 protein transport 34.1176 4 yes
GO:0022607 cellular component assembly 34.1176 4 no
GO:0010646 regulation of cell communication 31.7647 4 no
GO:0051246 regulation of protein metabolic process 30.5882 5 no
GO:0006886 intracellular protein transport 29.4118 4 yes
GO:0009966 regulation of signal transduction 28.2353 4 no
GO:0051049 regulation of transport 23.5294 4 no
GO:0044087 regulation of cellular component biogenesis 23.5294 4 no
GO:0009893 positive regulation of metabolic process 23.5294 4 no
GO:0033043 regulation of organelle organization 22.3529 5 no
GO:0010468 regulation of gene expression 22.3529 5 no
GO:0010604 positive regulation of macromolecule metabolic process 22.3529 5 no
GO:0048193 Golgi vesicle transport 21.1765 5 yes
GO:0051173 positive regulation of nitrogen compound metabolic process 21.1765 5 no
GO:0006888 endoplasmic reticulum to Golgi vesicle-mediated transport 17.6471 4 yes
GO:0061024 membrane organization 11.7647 4 yes
GO:0007030 Golgi organization 10.5882 5 yes
GO:0016050 vesicle organization 7.0588 5 yes
GO:0061025 membrane fusion 7.0588 5 yes
GO:0006906 vesicle fusion 5.8824 6 yes
GO:0048284 organelle fusion 5.8824 5 yes
GO:0090174 organelle membrane fusion 5.8824 6 yes
GO:0007264 small GTPase mediated signal transduction 3.5294 4 yes
GO:0048211 Golgi vesicle docking 3.5294 5 yes
GO:0048278 vesicle docking 3.5294 4 yes
GO:0048280 vesicle fusion with Golgi apparatus 3.5294 6 yes
GO:0032252 secretory granule localization 2.3529 4 yes
GO:1900076 regulation of cellular response to insulin stimulus 2.3529 4 yes

Disease

Term Name % Distance from top the of the tree Annotated in USO1_HUMAN
DOID:440 neuromuscular disease 2.3529 5 no
DOID:574 peripheral nervous system disease 2.3529 3 no
DOID:870 neuropathy 2.3529 4 no
DOID:0050700 cardiomyopathy 2.3529 4 no
DOID:0060036 intrinsic cardiomyopathy 2.3529 5 no
DOID:114 heart disease 2.3529 3 no
Uniprot ID Details Highest evidence Localizing into PSD HPA (protein expression in neurons)
GOGB1_HUMAN [view entry] [view interactions] Low throughput yes yes
CASP3_HUMAN [view interactions] Low throughput no yes
SC22A_HUMAN [view interactions] Low throughput no no
GBF1_HUMAN [view interactions] Low throughput no yes
GOGA2_HUMAN [view entry] [view interactions] Low throughput yes yes
GOSR1_HUMAN [view entry] [view interactions] Low throughput yes yes
BET1_HUMAN [view interactions] Low throughput no no
GOSR2_HUMAN [view interactions] Low throughput no yes
YKT6_HUMAN [view interactions] Low throughput no yes
STX5_HUMAN [view interactions] Low throughput no yes
SCFD1_HUMAN [view entry] [view interactions] Low throughput yes yes
RAB1A_HUMAN [view entry] [view interactions] Low throughput yes yes
RAB2A_HUMAN [view entry] [view interactions] Low throughput yes yes
ERP44_HUMAN [view interactions] Low throughput no yes
USO1_HUMAN [view entry] [view interactions] Low throughput yes yes
P53_HUMAN [view interactions] Low throughput no no
MK03_HUMAN [view entry] [view interactions] Low throughput yes yes
LCAP_HUMAN [view interactions] Low throughput no yes
UBR4_HUMAN [view entry] [view interactions] High throughput yes yes
YIPF3_HUMAN [view interactions] High throughput no yes
AT2C1_HUMAN [view interactions] High throughput no yes
UBIA1_HUMAN [view interactions] High throughput no no
SRRT_HUMAN [view interactions] High throughput no yes
AMRA1_HUMAN [view interactions] High throughput no yes
ZNT6_HUMAN [view interactions] High throughput no yes
INF2_HUMAN [view entry] [view interactions] High throughput yes yes
WNK1_HUMAN [view entry] [view interactions] High throughput yes no
YIF1B_HUMAN [view interactions] High throughput no yes
YTDC1_HUMAN [view interactions] High throughput no yes
CAF1A_HUMAN [view interactions] High throughput no yes
SO1B1_HUMAN [view interactions] High throughput no no
DDX20_HUMAN [view interactions] High throughput no no
ZN488_HUMAN [view interactions] High throughput no no
SNR27_HUMAN [view interactions] High throughput no yes
SEM4F_HUMAN [view entry] [view interactions] High throughput yes no
CPNE5_HUMAN [view entry] [view interactions] High throughput yes yes
FIBB_HUMAN [view entry] [view interactions] High throughput yes no
TXIP1_HUMAN [view interactions] High throughput no no
FACD2_HUMAN [view interactions] High throughput no no
BRCA1_HUMAN [view interactions] High throughput no yes
COPE_HUMAN [view interactions] High throughput no yes
CTNB1_HUMAN [view entry] [view interactions] High throughput yes yes
PIHD1_HUMAN [view interactions] High throughput no yes
UBC12_HUMAN [view entry] [view interactions] High throughput yes yes
RNF4_HUMAN [view interactions] High throughput no yes
ESR2_HUMAN [view interactions] High throughput no no
GLP1R_HUMAN [view interactions] High throughput no no
TERA_HUMAN [view entry] [view interactions] High throughput yes yes
VIR_HUMAN [view interactions] High throughput no yes
KPCD2_HUMAN [view interactions] High throughput no yes
ATX1_HUMAN [view interactions] High throughput no yes
BIRC3_HUMAN [view interactions] High throughput no no
LMBRL_HUMAN [view interactions] High throughput no no
TIF1B_HUMAN [view interactions] High throughput no yes
PKHA4_HUMAN [view interactions] High throughput no yes
MLP3B_HUMAN [view interactions] High throughput no yes
STAG2_HUMAN [view interactions] High throughput no yes
PDS5A_HUMAN [view interactions] High throughput no yes
CSN5_HUMAN [view interactions] High throughput no yes
CFAD_HUMAN [view interactions] High throughput no no
FNDC5_HUMAN [view interactions] High throughput no no
TRI37_HUMAN [view entry] [view interactions] High throughput yes yes
GPR17_HUMAN [view interactions] High throughput no no
CEA16_HUMAN [view interactions] High throughput no no
EFNB1_HUMAN [view interactions] High throughput no yes
GLIS2_HUMAN [view interactions] High throughput no no
AT7L1_HUMAN [view interactions] High throughput no yes
ANR22_HUMAN [view interactions] High throughput no no
GRAP1_HUMAN [view entry] [view interactions] High throughput yes yes
DLGP2_HUMAN [view entry] [view interactions] High throughput yes no
NUP62_HUMAN [view interactions] High throughput no yes
NTNG1_HUMAN [view interactions] High throughput no no
KLRG2_HUMAN [view interactions] High throughput no no
DNJB6_HUMAN [view entry] [view interactions] High throughput yes yes
PRTN3_HUMAN [view interactions] High throughput no no
CMTD1_HUMAN [view entry] [view interactions] High throughput yes yes
CDKAL_HUMAN [view interactions] High throughput no no
WIF1_HUMAN [view entry] [view interactions] High throughput yes no
TPST2_HUMAN [view interactions] High throughput no yes
SYT6_HUMAN [view entry] [view interactions] High throughput yes no
PRIC4_HUMAN [view interactions] High throughput no yes
CCR1_HUMAN [view interactions] High throughput no no
EP300_HUMAN [view interactions] High throughput no yes
EMC9_HUMAN [view interactions] High throughput no no
PDZD8_HUMAN [view interactions] High throughput no yes
EGFR_HUMAN [view interactions] High throughput no no
RASK_HUMAN [view entry] [view interactions] High throughput yes no
RIT1_HUMAN [view interactions] High throughput no yes
VINC_HUMAN [view entry] [view interactions] High throughput yes no
UBP28_HUMAN [view interactions] High throughput no yes
XIAP_HUMAN [view interactions] High throughput no yes
ZN593_HUMAN [view interactions] High throughput no yes
DPOE3_HUMAN [view interactions] High throughput no yes
SRC8_HUMAN [view entry] [view interactions] High throughput yes yes
DNJA1_HUMAN [view entry] [view interactions] High throughput yes yes
ENPL_HUMAN [view entry] [view interactions] High throughput yes yes
KHDR1_HUMAN [view interactions] High throughput no yes
NSF_HUMAN [view entry] [view interactions] High throughput yes yes
CSK2B_HUMAN [view entry] [view interactions] High throughput yes yes
DCTN1_HUMAN [view entry] [view interactions] High throughput yes yes
DCTN2_HUMAN [view entry] [view interactions] High throughput yes yes
EEA1_HUMAN [view entry] [view interactions] High throughput yes yes
CADH1_HUMAN [view entry] [view interactions] High throughput yes no
RN183_HUMAN [view interactions] High throughput no no
LEG9_HUMAN [view interactions] High throughput no yes
B3GA1_HUMAN [view interactions] High throughput no yes
CAV1_HUMAN [view interactions] High throughput no no
RCAS1_HUMAN [view interactions] High throughput no yes
EMD_HUMAN [view interactions] High throughput no yes
ERGI2_HUMAN [view interactions] High throughput no yes
CXA1_HUMAN [view entry] [view interactions] High throughput yes yes
TRAF3_HUMAN [view entry] [view interactions] High throughput yes yes
CXD3_HUMAN [view interactions] High throughput no no
LCK_HUMAN [view entry] [view interactions] High throughput yes no
BET1L_HUMAN [view interactions] High throughput no yes
NU155_HUMAN [view interactions] High throughput no yes
PCNT_HUMAN [view interactions] High throughput no yes
SC22B_HUMAN [view entry] [view interactions] High throughput yes no
RAB9A_HUMAN [view interactions] High throughput no yes
STX6_HUMAN [view interactions] High throughput no yes
GORS1_HUMAN [view interactions] High throughput no yes
SC24C_HUMAN [view entry] [view interactions] High throughput yes yes
GTSE1_HUMAN [view interactions] High throughput no no
CLH1_HUMAN [view entry] [view interactions] High throughput yes yes
SC16A_HUMAN [view interactions] High throughput no yes
KAPCA_HUMAN [view entry] [view interactions] High throughput yes yes
P3C2A_HUMAN [view interactions] High throughput no yes
AP2B1_HUMAN [view entry] [view interactions] High throughput yes yes
EPN4_HUMAN [view interactions] High throughput no yes
BRE1A_HUMAN [view interactions] High throughput no yes
KAPCB_HUMAN [view entry] [view interactions] High throughput yes yes
BMP1_HUMAN [view interactions] High throughput no yes
BMP2K_HUMAN [view interactions] High throughput no yes
CK5P2_HUMAN [view interactions] High throughput no yes
TMOD3_HUMAN [view interactions] High throughput no yes
FA83B_HUMAN [view interactions] High throughput no no
NP1L4_HUMAN [view entry] [view interactions] High throughput yes yes
GBB2_HUMAN [view entry] [view interactions] High throughput yes yes
MPRIP_HUMAN [view entry] [view interactions] High throughput yes yes
SEC13_HUMAN [view entry] [view interactions] High throughput yes yes
CEP72_HUMAN [view interactions] High throughput no yes
MYPT1_HUMAN [view entry] [view interactions] High throughput yes yes
ZN106_HUMAN [view interactions] High throughput no no
FA83H_HUMAN [view interactions] High throughput no yes
KC1A_HUMAN [view interactions] High throughput no yes
ARPC2_HUMAN [view entry] [view interactions] High throughput yes yes
MIPT3_HUMAN [view interactions] High throughput no yes
PCM1_HUMAN [view interactions] High throughput no yes
PDCD6_HUMAN [view interactions] High throughput no no
NPHP3_HUMAN [view interactions] High throughput no yes
CO4B_HUMAN [view interactions] High throughput no no
CYTSA_HUMAN [view interactions] High throughput no yes
NCBP1_HUMAN [view interactions] High throughput no yes
TBA1A_HUMAN [view entry] [view interactions] High throughput yes yes
KAP2_HUMAN [view entry] [view interactions] High throughput yes yes
TPM4_HUMAN [view entry] [view interactions] High throughput yes yes
YIPF5_HUMAN [view interactions] High throughput no yes
ENDD1_HUMAN [view interactions] High throughput no yes
MA1B1_HUMAN [view interactions] High throughput no yes
CLH2_HUMAN [view interactions] High throughput no no
GORS2_HUMAN [view interactions] High throughput no yes
GO45_HUMAN [view interactions] High throughput no yes
GALT2_HUMAN [view interactions] High throughput no yes
RBM14_HUMAN [view interactions] High throughput no yes
ABCF2_HUMAN [view interactions] High throughput no yes
F120A_HUMAN [view interactions] High throughput no yes
LG3BP_HUMAN [view interactions] High throughput no no
RABL3_HUMAN [view interactions] High throughput no yes
CE170_HUMAN [view interactions] High throughput no yes
GOGA3_HUMAN [view interactions] High throughput no yes
STON2_HUMAN [view interactions] High throughput no yes
KC1E_HUMAN [view entry] [view interactions] High throughput yes yes
UBX2A_HUMAN [view interactions] High throughput no no
NCOA5_HUMAN [view interactions] High throughput no yes
GOT1B_HUMAN [view interactions] High throughput no yes
ZFPL1_HUMAN [view interactions] High throughput no yes
FARP1_HUMAN [view entry] [view interactions] High throughput yes no
GOLI4_HUMAN [view interactions] High throughput no yes
SURF4_HUMAN [view interactions] High throughput no yes
GORAB_HUMAN [view interactions] High throughput no yes
TMEDA_HUMAN [view interactions] High throughput no yes
TM9S4_HUMAN [view interactions] High throughput no yes
FBRS_HUMAN [view interactions] High throughput no no
YIF1A_HUMAN [view interactions] High throughput no yes
TMED7_HUMAN [view interactions] High throughput no yes
LZTS2_HUMAN [view interactions] High throughput no no
TMOD1_HUMAN [view entry] [view interactions] High throughput yes yes
CEP68_HUMAN [view interactions] High throughput no yes
ACTL8_HUMAN [view interactions] High throughput no no
GAK_HUMAN [view entry] [view interactions] High throughput yes yes
P4HA1_HUMAN [view interactions] High throughput no yes
S35E1_HUMAN [view interactions] High throughput no yes
AP3M1_HUMAN [view interactions] High throughput no yes
CE290_HUMAN [view interactions] High throughput no no
LRRK2_HUMAN [view interactions] High throughput no yes
ODPA_HUMAN [view entry] [view interactions] High throughput yes yes
ERLN1_HUMAN [view entry] [view interactions] High throughput yes yes
SHAN3_HUMAN [view entry] [view interactions] High throughput yes no
PRIO_HUMAN [view entry] [view interactions] High throughput yes yes
ARF6_HUMAN [view entry] [view interactions] High throughput yes yes
TP4A3_HUMAN [view interactions] High throughput no no
GSTK1_HUMAN [view entry] [view interactions] High throughput yes yes
CDC5L_HUMAN [view interactions] High throughput no yes
AAKB1_HUMAN [view interactions] High throughput no yes
ANS1B_HUMAN [view entry] [view interactions] High throughput yes yes
AT2L2_HUMAN [view interactions] High throughput no yes
XPO7_HUMAN [view entry] [view interactions] High throughput yes yes
DUS12_HUMAN [view interactions] High throughput no no
GABP1_HUMAN [view interactions] High throughput no yes
CA094_HUMAN [view interactions] High throughput no no
NEMO_HUMAN [view interactions] High throughput no yes
FOXQ1_HUMAN [view interactions] High throughput no no
PCNA_HUMAN [view interactions] High throughput no no
TMM17_HUMAN [view interactions] High throughput no yes
TGON2_HUMAN [view interactions] High throughput no yes
ALK_HUMAN [view entry] [view interactions] High throughput yes yes
EPHA8_HUMAN [view interactions] High throughput no no
FGFR1_HUMAN [view interactions] High throughput no yes
VGFR3_HUMAN [view interactions] High throughput no yes
MUSK_HUMAN [view entry] [view interactions] High throughput yes no
NTRK3_HUMAN [view entry] [view interactions] High throughput yes yes
PGFRB_HUMAN [view interactions] High throughput no yes
AKAP9_HUMAN [view entry] [view interactions] High throughput yes yes
RL9_HUMAN [view entry] [view interactions] High throughput yes yes
SNW1_HUMAN [view interactions] High throughput no yes
BYST_HUMAN [view interactions] High throughput no yes
PRP6_HUMAN [view interactions] High throughput no yes
UT14A_HUMAN [view interactions] High throughput no yes
MO4L1_HUMAN [view interactions] High throughput no yes
SF01_HUMAN [view interactions] High throughput no yes
LENG1_HUMAN [view interactions] High throughput no no
PROF1_HUMAN [view entry] [view interactions] High throughput yes yes
NONO_HUMAN [view interactions] High throughput no yes
NCOA2_HUMAN [view interactions] High throughput no no
FOXP3_HUMAN [view interactions] High throughput no no
MYOME_HUMAN [view interactions] High throughput no no
TRIPB_HUMAN [view interactions] High throughput no yes
KAP3_HUMAN [view entry] [view interactions] High throughput yes yes
F184A_HUMAN [view interactions] High throughput no no
HUWE1_HUMAN [view interactions] High throughput no yes
MDM2_HUMAN [view interactions] High throughput no yes
EED_HUMAN [view interactions] High throughput no yes
RN114_HUMAN [view interactions] High throughput no no
EFNB2_HUMAN [view entry] [view interactions] High throughput yes yes
SETD9_HUMAN [view interactions] High throughput no no
TXD11_HUMAN [view interactions] High throughput no yes
ACL6A_HUMAN [view interactions] High throughput no yes
SCN2B_HUMAN [view interactions] High throughput no no
CP1A1_HUMAN [view interactions] High throughput no yes
NTRK1_HUMAN [view interactions] High throughput no yes
AP2A1_HUMAN [view entry] [view interactions] High throughput yes yes
CO4A_HUMAN [view interactions] High throughput no no
CLCA_HUMAN [view entry] [view interactions] High throughput yes no
CLCB_HUMAN [view entry] [view interactions] High throughput yes yes
PKP2_HUMAN [view interactions] High throughput no yes
RBBP6_HUMAN [view interactions] High throughput no yes
TPM1_HUMAN [view entry] [view interactions] High throughput yes no
TNK1_HUMAN [view interactions] High throughput no yes
LRRF2_HUMAN [view interactions] High throughput no yes
BCLF1_HUMAN [view interactions] High throughput no yes
ACK1_HUMAN [view interactions] High throughput no yes
SC24B_HUMAN [view interactions] High throughput no yes
BTBD3_HUMAN [view interactions] High throughput no yes
CP131_HUMAN [view interactions] High throughput no no
COG1_HUMAN [view interactions] Computational no yes
COPB2_HUMAN [view entry] [view interactions] Computational yes yes
COG6_HUMAN [view interactions] Computational no yes
LMAN1_HUMAN [view interactions] Computational no yes
CCNB1_HUMAN [view interactions] Computational no no
ARF1_HUMAN [view entry] [view interactions] Computational yes yes
CCNB2_HUMAN [view interactions] Computational no yes
SC31A_HUMAN [view entry] [view interactions] Computational yes yes
SC22C_HUMAN [view interactions] Computational no no
SC23A_HUMAN [view entry] [view interactions] Computational yes yes
TPC10_HUMAN [view interactions] Computational no no
RAB1B_HUMAN [view entry] [view interactions] Computational yes yes
S23IP_HUMAN [view interactions] Computational no yes
COPB_HUMAN [view interactions] Computational no yes
GOGA5_HUMAN [view interactions] Computational no yes
CDK1_HUMAN [view interactions] Computational no no
COG2_HUMAN [view interactions] Computational no no
TPPC1_HUMAN [view interactions] Computational no yes
STX17_HUMAN [view interactions] Computational no yes
COPA_HUMAN [view entry] [view interactions] Computational yes yes
SC24A_HUMAN [view interactions] Computational no no
TPC6A_HUMAN [view interactions] Computational no yes
COG3_HUMAN [view entry] [view interactions] Computational yes yes