Features Interactions Isoform Disease Linear motifs Fingerprint Network All partners

EFNB2_HUMAN

(Microbial infection) Acts as a receptor for Hendra virus and Nipah virus. [View more on UniProt]

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No data found.

No data found.

ELM instance Name Type Start End Partner
ELMI003879 LIG_SH2_NCK_1 LIG 302 308 -
ELMI003879 LIG_SH2_NCK_1 LIG 302 308 -

Molecular function

Term Name % Distance from the top of the tree Annotated in EFNB2_HUMAN
GO:0043168 anion binding 46.4286 4 no
GO:0000166 nucleotide binding 44.6429 4 no
GO:0017076 purine nucleotide binding 44.6429 5 no
GO:0032555 purine ribonucleotide binding 44.6429 4 no
GO:0035639 purine ribonucleoside triphosphate binding 44.6429 4 no
GO:0005525 GTP binding 30.3571 5 no
GO:0016462 pyrophosphatase activity 30.3571 5 no
GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 30.3571 4 no
GO:0017111 ribonucleoside triphosphate phosphatase activity 30.3571 6 no
GO:0019001 guanyl nucleotide binding 30.3571 6 no
GO:0032561 guanyl ribonucleotide binding 30.3571 5 no
GO:0019900 kinase binding 28.5714 4 no
GO:0019901 protein kinase binding 28.5714 5 no
GO:0003924 GTPase activity 28.5714 7 no
GO:0046875 ephrin receptor binding 10.7143 4 yes
GO:0001618 virus receptor activity 5.3571 4 yes

Biological process

Term Name % Distance from top the of the tree Annotated in EFNB2_HUMAN
GO:0048522 positive regulation of cellular process 66.0714 4 yes
GO:0048523 negative regulation of cellular process 53.5714 4 yes
GO:0051128 regulation of cellular component organization 53.5714 4 yes
GO:0060255 regulation of macromolecule metabolic process 50.0000 4 no
GO:0008104 protein localization 44.6429 4 no
GO:0051049 regulation of transport 41.0714 4 yes
GO:0009889 regulation of biosynthetic process 41.0714 4 no
GO:0010556 regulation of macromolecule biosynthetic process 41.0714 5 no
GO:0031323 regulation of cellular metabolic process 41.0714 4 no
GO:0031326 regulation of cellular biosynthetic process 41.0714 5 no
GO:0080090 regulation of primary metabolic process 41.0714 4 no
GO:0010468 regulation of gene expression 39.2857 6 no
GO:0010646 regulation of cell communication 39.2857 4 no
GO:0006996 organelle organization 37.5000 4 no
GO:0022607 cellular component assembly 37.5000 4 no
GO:0009893 positive regulation of metabolic process 37.5000 4 no
GO:0010604 positive regulation of macromolecule metabolic process 37.5000 5 no
GO:0031344 regulation of cell projection organization 35.7143 5 yes
GO:0120035 regulation of plasma membrane bounded cell projection organization 35.7143 6 yes
GO:0071702 organic substance transport 35.7143 4 no
GO:0071705 nitrogen compound transport 35.7143 4 no
GO:0009966 regulation of signal transduction 35.7143 4 no
GO:0030030 cell projection organization 33.9286 4 yes
GO:0051246 regulation of protein metabolic process 33.9286 5 no
GO:1902531 regulation of intracellular signal transduction 33.9286 5 no
GO:0030334 regulation of cell migration 33.9286 5 no
GO:2000145 regulation of cell motility 33.9286 4 no
GO:0048584 positive regulation of response to stimulus 32.1429 4 no
GO:0060341 regulation of cellular localization 32.1429 4 no
GO:0022603 regulation of anatomical structure morphogenesis 30.3571 4 yes
GO:0030155 regulation of cell adhesion 30.3571 4 yes
GO:0042127 regulation of cell population proliferation 30.3571 4 yes
GO:0051240 positive regulation of multicellular organismal process 30.3571 4 yes
GO:0120036 plasma membrane bounded cell projection organization 30.3571 5 yes
GO:0015031 protein transport 30.3571 4 no
GO:0031325 positive regulation of cellular metabolic process 30.3571 5 no
GO:0032880 regulation of protein localization 30.3571 5 no
GO:0008284 positive regulation of cell population proliferation 28.5714 5 yes
GO:0010647 positive regulation of cell communication 28.5714 5 no
GO:0023056 positive regulation of signaling 28.5714 4 no
GO:0033043 regulation of organelle organization 28.5714 5 no
GO:0002684 positive regulation of immune system process 28.5714 4 yes
GO:0060627 regulation of vesicle-mediated transport 26.7857 4 yes
GO:0009892 negative regulation of metabolic process 26.7857 4 no
GO:0042981 regulation of apoptotic process 26.7857 5 no
GO:0043067 regulation of programmed cell death 26.7857 4 no
GO:0051130 positive regulation of cellular component organization 26.7857 5 no
GO:0030335 positive regulation of cell migration 26.7857 6 no
GO:0040017 positive regulation of locomotion 26.7857 4 no
GO:2000147 positive regulation of cell motility 26.7857 5 no
GO:0051050 positive regulation of transport 26.7857 4 no
GO:0045785 positive regulation of cell adhesion 25.0000 5 yes
GO:0051129 negative regulation of cellular component organization 25.0000 5 yes
GO:0006886 intracellular protein transport 25.0000 4 no
GO:0098657 import into cell 25.0000 4 no
GO:0009967 positive regulation of signal transduction 25.0000 5 no
GO:0010605 negative regulation of macromolecule metabolic process 25.0000 5 no
GO:0031324 negative regulation of cellular metabolic process 25.0000 5 no
GO:0031399 regulation of protein modification process 25.0000 6 no
GO:0044087 regulation of cellular component biogenesis 25.0000 4 no
GO:0051247 positive regulation of protein metabolic process 25.0000 6 no
GO:0007010 cytoskeleton organization 25.0000 5 no
GO:0051094 positive regulation of developmental process 23.2143 4 yes
GO:1902533 positive regulation of intracellular signal transduction 23.2143 6 no
GO:0141124 intracellular signaling cassette 23.2143 4 no
GO:0031175 neuron projection development 21.4286 6 yes
GO:0045595 regulation of cell differentiation 21.4286 4 yes
GO:0097435 supramolecular fiber organization 21.4286 4 no
GO:0001932 regulation of protein phosphorylation 21.4286 7 no
GO:0009891 positive regulation of biosynthetic process 21.4286 5 no
GO:0010557 positive regulation of macromolecule biosynthetic process 21.4286 6 no
GO:0019220 regulation of phosphate metabolic process 21.4286 6 no
GO:0031328 positive regulation of cellular biosynthetic process 21.4286 6 no
GO:0042325 regulation of phosphorylation 21.4286 7 no
GO:0051174 regulation of phosphorus metabolic process 21.4286 5 no
GO:0006796 phosphate-containing compound metabolic process 21.4286 4 no
GO:0036211 protein modification process 21.4286 4 no
GO:0043412 macromolecule modification 21.4286 4 no
GO:0071310 cellular response to organic substance 21.4286 4 no
GO:2000026 regulation of multicellular organismal development 21.4286 4 no
GO:0010975 regulation of neuron projection development 19.6429 7 yes
GO:0034330 cell junction organization 19.6429 4 yes
GO:0007167 enzyme-linked receptor protein signaling pathway 19.6429 4 yes
GO:0007169 cell surface receptor protein tyrosine kinase signaling pathway 19.6429 5 yes
GO:0022407 regulation of cell-cell adhesion 17.8571 5 yes
GO:0022409 positive regulation of cell-cell adhesion 16.0714 6 yes
GO:0032101 regulation of response to external stimulus 16.0714 4 yes
GO:0045216 cell-cell junction organization 16.0714 5 yes
GO:0045597 positive regulation of cell differentiation 16.0714 5 yes
GO:0050865 regulation of cell activation 16.0714 4 yes
GO:0050867 positive regulation of cell activation 16.0714 5 yes
GO:0051249 regulation of lymphocyte activation 16.0714 5 yes
GO:0051251 positive regulation of lymphocyte activation 16.0714 6 yes
GO:0002694 regulation of leukocyte activation 16.0714 4 yes
GO:0002696 positive regulation of leukocyte activation 16.0714 5 yes
GO:0030100 regulation of endocytosis 14.2857 5 yes
GO:0050863 regulation of T cell activation 14.2857 6 yes
GO:0050870 positive regulation of T cell activation 14.2857 7 yes
GO:1903037 regulation of leukocyte cell-cell adhesion 14.2857 6 yes
GO:1903039 positive regulation of leukocyte cell-cell adhesion 14.2857 7 yes
GO:0002009 morphogenesis of an epithelium 14.2857 4 yes
GO:0010977 negative regulation of neuron projection development 12.5000 7 yes
GO:0031345 negative regulation of cell projection organization 12.5000 6 yes
GO:0048013 ephrin receptor signaling pathway 12.5000 6 yes
GO:0097485 neuron projection guidance 12.5000 7 yes
GO:0007411 axon guidance 12.5000 8 yes
GO:0008285 negative regulation of cell population proliferation 10.7143 5 yes
GO:0048259 regulation of receptor-mediated endocytosis 10.7143 6 yes
GO:0050678 regulation of epithelial cell proliferation 10.7143 5 yes
GO:0060562 epithelial tube morphogenesis 10.7143 4 yes
GO:0001667 ameboidal-type cell migration 10.7143 4 yes
GO:0034332 adherens junction organization 8.9286 6 yes
GO:0050920 regulation of chemotaxis 8.9286 4 yes
GO:0010631 epithelial cell migration 7.1429 5 yes
GO:0043542 endothelial cell migration 7.1429 6 yes
GO:0048514 blood vessel morphogenesis 7.1429 4 yes
GO:0002090 regulation of receptor internalization 7.1429 7 yes
GO:0050680 negative regulation of epithelial cell proliferation 5.3571 6 yes
GO:0072178 nephric duct morphogenesis 5.3571 5 yes
GO:0010837 regulation of keratinocyte proliferation 3.5714 6 yes
GO:0010839 negative regulation of keratinocyte proliferation 3.5714 7 yes
GO:0043534 blood vessel endothelial cell migration 3.5714 7 yes
GO:0043616 keratinocyte proliferation 3.5714 4 yes
GO:0048845 venous blood vessel morphogenesis 3.5714 5 yes
GO:0051147 regulation of muscle cell differentiation 3.5714 5 yes
GO:0051149 positive regulation of muscle cell differentiation 3.5714 6 yes
GO:0051153 regulation of striated muscle cell differentiation 3.5714 6 yes
GO:0051155 positive regulation of striated muscle cell differentiation 3.5714 7 yes
GO:1903847 regulation of aorta morphogenesis 3.5714 6 yes
GO:1903849 positive regulation of aorta morphogenesis 3.5714 6 yes
GO:1905207 regulation of cardiocyte differentiation 3.5714 5 yes
GO:1905209 positive regulation of cardiocyte differentiation 3.5714 5 yes
GO:1905651 regulation of artery morphogenesis 3.5714 5 yes
GO:1905653 positive regulation of artery morphogenesis 3.5714 5 yes
GO:2000725 regulation of cardiac muscle cell differentiation 3.5714 6 yes
GO:2000727 positive regulation of cardiac muscle cell differentiation 3.5714 6 yes
GO:0002042 cell migration involved in sprouting angiogenesis 3.5714 8 yes

Disease

No data found.

Uniprot ID Details Highest evidence Localizing into PSD HPA (protein expression in neurons)
NCK2_HUMAN [view entry] [view interactions] Low throughput yes yes
SRC_HUMAN [view entry] [view interactions] Low throughput yes no
EPHA4_HUMAN [view entry] [view interactions] Low throughput yes yes
EPHB3_HUMAN [view interactions] Low throughput no yes
EPHB4_HUMAN [view interactions] Low throughput no yes
EFNB1_HUMAN [view interactions] Low throughput no yes
DAB1_HUMAN [view interactions] Low throughput no yes
RELN_HUMAN [view entry] [view interactions] Low throughput yes no
EPHB2_HUMAN [view entry] [view interactions] Low throughput yes yes
CXA1_HUMAN [view entry] [view interactions] Low throughput yes yes
PHAG1_HUMAN [view interactions] Low throughput no yes
EPHB1_HUMAN [view interactions] Low throughput no no
EPHA3_HUMAN [view interactions] Low throughput no yes
AQP1_HUMAN [view entry] [view interactions] Low throughput yes no
EFNB2_HUMAN [view entry] [view interactions] Low throughput yes yes
PICK1_HUMAN [view entry] [view interactions] High throughput yes yes
F1712_HUMAN [view interactions] High throughput no no
P85B_HUMAN [view interactions] High throughput no yes
PHLP1_HUMAN [view interactions] High throughput no yes
TSN3_HUMAN [view interactions] High throughput no yes
SDC3_HUMAN [view interactions] High throughput no yes
TYK2_HUMAN [view interactions] High throughput no no
SDC2_HUMAN [view entry] [view interactions] High throughput yes yes
PK3CA_HUMAN [view entry] [view interactions] High throughput yes yes
PK3CB_HUMAN [view interactions] High throughput no yes
MAOX_HUMAN [view interactions] High throughput no yes
EI2BB_HUMAN [view entry] [view interactions] High throughput yes yes
KIF14_HUMAN [view interactions] High throughput no no
TIGD5_HUMAN [view interactions] High throughput no no
PKN3_HUMAN [view interactions] High throughput no yes
DEN6A_HUMAN [view interactions] High throughput no yes
P4K2B_HUMAN [view interactions] High throughput no yes
NGBR_HUMAN [view interactions] High throughput no no
RADIL_HUMAN [view interactions] High throughput no no
DPH1_HUMAN [view interactions] High throughput no yes
DIP2B_HUMAN [view entry] [view interactions] High throughput yes yes
DAB2_HUMAN [view interactions] High throughput no yes
MYH6_HUMAN [view entry] [view interactions] High throughput yes no
DYN2_HUMAN [view entry] [view interactions] High throughput yes yes
CLH1_HUMAN [view entry] [view interactions] High throughput yes yes
AP2A2_HUMAN [view entry] [view interactions] High throughput yes yes
AP2B1_HUMAN [view entry] [view interactions] High throughput yes yes
AP2M1_HUMAN [view entry] [view interactions] High throughput yes yes
PARD3_HUMAN [view interactions] High throughput no yes
TMM17_HUMAN [view interactions] High throughput no yes
TM216_HUMAN [view interactions] High throughput no no
RASK_HUMAN [view entry] [view interactions] High throughput yes no
RASN_HUMAN [view entry] [view interactions] High throughput yes no
RASH_HUMAN [view entry] [view interactions] High throughput yes no
KCNJ2_HUMAN [view entry] [view interactions] High throughput yes yes
CFTR_HUMAN [view interactions] High throughput no no
KCNK3_HUMAN [view interactions] High throughput no no
ANR46_HUMAN [view interactions] High throughput no yes
CAND2_HUMAN [view entry] [view interactions] High throughput yes no
EI2BD_HUMAN [view interactions] High throughput no yes
MA7D2_HUMAN [view interactions] High throughput no yes
EPHA5_HUMAN [view interactions] High throughput no no
SAAL1_HUMAN [view interactions] High throughput no yes
DIP2A_HUMAN [view entry] [view interactions] High throughput yes no
PKHH3_HUMAN [view interactions] High throughput no no
P121A_HUMAN [view interactions] High throughput no yes
MTMR5_HUMAN [view entry] [view interactions] High throughput yes no
RETST_HUMAN [view interactions] High throughput no yes
EFNMT_HUMAN [view interactions] High throughput no yes
P85A_HUMAN [view interactions] High throughput no yes
P55G_HUMAN [view interactions] High throughput no yes
UBE3C_HUMAN [view entry] [view interactions] High throughput yes yes
DYN3_HUMAN [view entry] [view interactions] High throughput yes no
USO1_HUMAN [view entry] [view interactions] High throughput yes yes
MA7D3_HUMAN [view interactions] High throughput no no
AT2B2_HUMAN [view entry] [view interactions] High throughput yes yes
MED16_HUMAN [view interactions] High throughput no yes
PKP2_HUMAN [view interactions] High throughput no yes
HPS3_HUMAN [view interactions] High throughput no yes
AAAS_HUMAN [view interactions] High throughput no yes
PKHG4_HUMAN [view interactions] High throughput no no
MTMR1_HUMAN [view interactions] High throughput no yes
F120A_HUMAN [view interactions] High throughput no yes
MRPP3_HUMAN [view interactions] High throughput no yes
NF1_HUMAN [view entry] [view interactions] High throughput yes no
LMBR1_HUMAN [view interactions] High throughput no yes
EI2BE_HUMAN [view interactions] High throughput no yes
DAD1_HUMAN [view entry] [view interactions] High throughput yes yes
RGS3_HUMAN [view interactions] High throughput no no
TEX2_HUMAN [view interactions] High throughput no yes
HNRPL_HUMAN [view interactions] High throughput no yes
UBQL1_HUMAN [view interactions] High throughput no yes
TM9S3_HUMAN [view interactions] High throughput no yes
RPN1_HUMAN [view entry] [view interactions] High throughput yes yes
S39AB_HUMAN [view interactions] High throughput no no
CD28_HUMAN [view interactions] High throughput no no
PLPL6_HUMAN [view entry] [view interactions] High throughput yes yes
RRFM_HUMAN [view interactions] High throughput no yes
RAC1_HUMAN [view entry] [view interactions] High throughput yes no
RHOA_HUMAN [view entry] [view interactions] High throughput yes yes
RHOJ_HUMAN [view interactions] High throughput no yes
RHOQ_HUMAN [view interactions] High throughput no no
RAC3_HUMAN [view entry] [view interactions] High throughput yes no
RHOF_HUMAN [view interactions] High throughput no no
RHOH_HUMAN [view interactions] High throughput no yes
RND3_HUMAN [view interactions] High throughput no no
CDC42_HUMAN [view entry] [view interactions] High throughput yes yes
P53_HUMAN [view interactions] High throughput no no
PZRN3_HUMAN [view interactions] High throughput no yes
RHDF2_HUMAN [view interactions] High throughput no yes
DNJC5_HUMAN [view interactions] High throughput no yes
ARF6_HUMAN [view entry] [view interactions] High throughput yes yes
B3GA1_HUMAN [view interactions] High throughput no yes
CK052_HUMAN [view interactions] High throughput no no
CAV1_HUMAN [view interactions] High throughput no no
CXAR_HUMAN [view interactions] High throughput no yes
DIRA3_HUMAN [view interactions] High throughput no yes
RCAS1_HUMAN [view interactions] High throughput no yes
EZRI_HUMAN [view entry] [view interactions] High throughput yes no
CXD3_HUMAN [view interactions] High throughput no no
LAMP1_HUMAN [view entry] [view interactions] High throughput yes yes
LAMP2_HUMAN [view interactions] High throughput no yes
LAMP3_HUMAN [view interactions] High throughput no no
LTOR1_HUMAN [view entry] [view interactions] High throughput yes yes
LCK_HUMAN [view entry] [view interactions] High throughput yes no
LYN_HUMAN [view entry] [view interactions] High throughput yes no
MARCS_HUMAN [view entry] [view interactions] High throughput yes yes
AFAD_HUMAN [view entry] [view interactions] High throughput yes yes
OCLN_HUMAN [view interactions] High throughput no no
RB11A_HUMAN [view entry] [view interactions] High throughput yes yes
RAB2A_HUMAN [view entry] [view interactions] High throughput yes yes
RAB35_HUMAN [view entry] [view interactions] High throughput yes yes
RAB5A_HUMAN [view entry] [view interactions] High throughput yes yes
RAB5C_HUMAN [view entry] [view interactions] High throughput yes yes
RADI_HUMAN [view entry] [view interactions] High throughput yes yes
RHOB_HUMAN [view entry] [view interactions] High throughput yes no
SC61B_HUMAN [view interactions] High throughput no yes
STX4_HUMAN [view entry] [view interactions] High throughput yes no
STX6_HUMAN [view interactions] High throughput no yes
STX7_HUMAN [view entry] [view interactions] High throughput yes yes
ZFPL1_HUMAN [view interactions] High throughput no yes
ARL4C_HUMAN [view interactions] High throughput no yes
ARL5A_HUMAN [view interactions] High throughput no yes
AR13B_HUMAN [view interactions] High throughput no yes
ARL14_HUMAN [view interactions] High throughput no no
ARL15_HUMAN [view interactions] High throughput no yes
SSR3_HUMAN [view interactions] High throughput no yes