CAND2_HUMAN
Evidence for PS localization
Functions
Probable assembly factor of SCF (SKP1-CUL1-F-box protein) E3 ubiquitin ligase complexes that promotes the exchange of the substrate-recognition F-box subunit in SCF complexes, thereby playing a key role in the cellular repertoire of SCF complexes. [View more on UniProt]
Protein features
Binary interactions with known binding regions
To display all evidence describing the interaction with a partner, click on the protein name left to the bars.
Network
Isoforms
Disease-causing germline mutations
No data found.
Linear motifs
No annotated instance was found. To search for linear motifs, use the ELM prediction server.
Fingerprint
Molecular function
No data found.
Biological process
| Term | Name | % | Distance from top the of the tree | Annotated in CAND2_HUMAN |
|---|---|---|---|---|
| GO:0048522 | positive regulation of cellular process | 58.8235 | 4 | yes |
| GO:0060255 | regulation of macromolecule metabolic process | 41.1765 | 4 | yes |
| GO:0009966 | regulation of signal transduction | 41.1765 | 4 | no |
| GO:0010646 | regulation of cell communication | 41.1765 | 4 | no |
| GO:0009893 | positive regulation of metabolic process | 35.2941 | 4 | yes |
| GO:0010468 | regulation of gene expression | 35.2941 | 5 | yes |
| GO:0010604 | positive regulation of macromolecule metabolic process | 35.2941 | 5 | yes |
| GO:0048523 | negative regulation of cellular process | 35.2941 | 4 | no |
| GO:0051049 | regulation of transport | 35.2941 | 4 | no |
| GO:0006996 | organelle organization | 35.2941 | 4 | no |
| GO:0032880 | regulation of protein localization | 35.2941 | 5 | no |
| GO:0060341 | regulation of cellular localization | 35.2941 | 4 | no |
| GO:0031323 | regulation of cellular metabolic process | 29.4118 | 4 | yes |
| GO:0036211 | protein modification process | 29.4118 | 4 | yes |
| GO:0043412 | macromolecule modification | 29.4118 | 4 | yes |
| GO:0051171 | regulation of nitrogen compound metabolic process | 29.4118 | 4 | yes |
| GO:0080090 | regulation of primary metabolic process | 29.4118 | 4 | yes |
| GO:0030030 | cell projection organization | 29.4118 | 4 | no |
| GO:0031175 | neuron projection development | 29.4118 | 6 | no |
| GO:0051128 | regulation of cellular component organization | 29.4118 | 4 | no |
| GO:0051240 | positive regulation of multicellular organismal process | 29.4118 | 4 | no |
| GO:0120036 | plasma membrane bounded cell projection organization | 29.4118 | 5 | no |
| GO:0008104 | protein localization | 29.4118 | 4 | no |
| GO:0022607 | cellular component assembly | 23.5294 | 4 | yes |
| GO:0031325 | positive regulation of cellular metabolic process | 23.5294 | 5 | yes |
| GO:0032446 | protein modification by small protein conjugation | 23.5294 | 6 | yes |
| GO:0051173 | positive regulation of nitrogen compound metabolic process | 23.5294 | 5 | yes |
| GO:0070647 | protein modification by small protein conjugation or removal | 23.5294 | 5 | yes |
| GO:0007411 | axon guidance | 23.5294 | 8 | no |
| GO:0045595 | regulation of cell differentiation | 23.5294 | 4 | no |
| GO:0071310 | cellular response to organic substance | 23.5294 | 4 | no |
| GO:0097485 | neuron projection guidance | 23.5294 | 7 | no |
| GO:0051246 | regulation of protein metabolic process | 23.5294 | 5 | no |
| GO:0009892 | negative regulation of metabolic process | 23.5294 | 4 | no |
| GO:0009967 | positive regulation of signal transduction | 23.5294 | 5 | no |
| GO:0010605 | negative regulation of macromolecule metabolic process | 23.5294 | 5 | no |
| GO:0010647 | positive regulation of cell communication | 23.5294 | 5 | no |
| GO:0023056 | positive regulation of signaling | 23.5294 | 4 | no |
| GO:0048584 | positive regulation of response to stimulus | 23.5294 | 4 | no |
| GO:1903829 | positive regulation of protein localization | 23.5294 | 5 | no |
| GO:0030334 | regulation of cell migration | 23.5294 | 5 | no |
| GO:2000145 | regulation of cell motility | 23.5294 | 4 | no |
| GO:0006355 | regulation of DNA-templated transcription | 17.6471 | 6 | yes |
| GO:0009889 | regulation of biosynthetic process | 17.6471 | 4 | yes |
| GO:0010556 | regulation of macromolecule biosynthetic process | 17.6471 | 5 | yes |
| GO:0016567 | protein ubiquitination | 17.6471 | 7 | yes |
| GO:0019219 | regulation of nucleobase-containing compound metabolic process | 17.6471 | 5 | yes |
| GO:0031326 | regulation of cellular biosynthetic process | 17.6471 | 5 | yes |
| GO:0051252 | regulation of RNA metabolic process | 17.6471 | 5 | yes |
| GO:1903506 | regulation of nucleic acid-templated transcription | 17.6471 | 7 | yes |
| GO:2001141 | regulation of RNA biosynthetic process | 17.6471 | 6 | yes |
| GO:0009891 | positive regulation of biosynthetic process | 11.7647 | 5 | yes |
| GO:0010557 | positive regulation of macromolecule biosynthetic process | 11.7647 | 6 | yes |
| GO:0031328 | positive regulation of cellular biosynthetic process | 11.7647 | 6 | yes |
| GO:0045893 | positive regulation of DNA-templated transcription | 11.7647 | 7 | yes |
| GO:0045935 | positive regulation of nucleobase-containing compound metabolic process | 11.7647 | 6 | yes |
| GO:0051254 | positive regulation of RNA metabolic process | 11.7647 | 6 | yes |
| GO:1902680 | positive regulation of RNA biosynthetic process | 11.7647 | 7 | yes |
| GO:1903508 | positive regulation of nucleic acid-templated transcription | 11.7647 | 8 | yes |
Disease
No data found.
All partners
| Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
|---|---|---|---|---|
| CNOT3_HUMAN | [view interactions] | Low throughput | no | yes |
| CUL1_HUMAN | [view interactions] | Low throughput | no | yes |
| TBP_HUMAN | [view interactions] | Low throughput | no | yes |
| UBE3C_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| UB2D1_HUMAN | [view interactions] | Low throughput | no | yes |
| B2L14_HUMAN | [view interactions] | High throughput | no | yes |
| P2RY6_HUMAN | [view interactions] | High throughput | no | no |
| UN93B_HUMAN | [view interactions] | High throughput | no | yes |
| EGFR_HUMAN | [view interactions] | High throughput | no | no |
| KCNQ1_HUMAN | [view interactions] | High throughput | no | yes |
| CAV3_HUMAN | [view interactions] | High throughput | no | no |
| TX101_HUMAN | [view interactions] | High throughput | no | no |
| CIDEB_HUMAN | [view interactions] | High throughput | no | yes |
| SYPH_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FHL2_HUMAN | [view interactions] | High throughput | no | yes |
| STOM_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DNJB6_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GRK5_HUMAN | [view interactions] | High throughput | no | yes |
| CAH9_HUMAN | [view interactions] | High throughput | no | no |
| IQCB1_HUMAN | [view interactions] | High throughput | no | no |
| FBX32_HUMAN | [view interactions] | High throughput | no | no |
| GLP1R_HUMAN | [view interactions] | High throughput | no | no |
| EED_HUMAN | [view interactions] | High throughput | no | yes |
| TMIG3_HUMAN | [view interactions] | High throughput | no | no |
| AA3R_HUMAN | [view interactions] | High throughput | no | no |
| VTI1B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| EFNB2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| BASI_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| TN13B_HUMAN | [view interactions] | High throughput | no | no |
| CD244_HUMAN | [view interactions] | High throughput | no | no |
| PE2R3_HUMAN | [view interactions] | High throughput | no | no |
| SCN2B_HUMAN | [view interactions] | High throughput | no | no |
| AL3A2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| 5HT6R_HUMAN | [view interactions] | High throughput | no | yes |
| CAF1A_HUMAN | [view interactions] | High throughput | no | yes |
| PTPRN_HUMAN | [view interactions] | High throughput | no | yes |
| TPTE_HUMAN | [view interactions] | High throughput | no | no |
| SIGL1_HUMAN | [view interactions] | High throughput | no | no |
| EPHA1_HUMAN | [view interactions] | High throughput | no | yes |
| ACM4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SDC2_HUMAN | [view interactions] | High throughput | no | yes |
| NPY2R_HUMAN | [view interactions] | High throughput | no | no |
| 5HT2C_HUMAN | [view interactions] | High throughput | no | no |
| F174A_HUMAN | [view interactions] | High throughput | no | yes |
| LPAR4_HUMAN | [view interactions] | High throughput | no | no |
| ACM3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FZD10_HUMAN | [view interactions] | High throughput | no | no |
| RHG36_HUMAN | [view interactions] | High throughput | no | yes |
| TM108_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FACD2_HUMAN | [view interactions] | High throughput | no | no |
| CXA1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RBX1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| S15A3_HUMAN | [view interactions] | High throughput | no | yes |
| TPTE2_HUMAN | [view interactions] | High throughput | no | no |
| LMBRL_HUMAN | [view interactions] | High throughput | no | no |
| TIF1B_HUMAN | [view interactions] | High throughput | no | yes |
| PKHA4_HUMAN | [view interactions] | High throughput | no | yes |
| CSN5_HUMAN | [view interactions] | High throughput | no | yes |
| DJC15_HUMAN | [view interactions] | High throughput | no | no |
| DNJC1_HUMAN | [view interactions] | High throughput | no | yes |
| DDRGK_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| C5AR1_HUMAN | [view interactions] | High throughput | no | yes |
| NPTN_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SLAF9_HUMAN | [view interactions] | High throughput | no | yes |
| S10A6_HUMAN | [view interactions] | High throughput | no | yes |
| DLK2_HUMAN | [view interactions] | High throughput | no | no |
| CD83_HUMAN | [view interactions] | High throughput | no | yes |
| CXCR4_HUMAN | [view interactions] | High throughput | no | no |
| TACD2_HUMAN | [view interactions] | High throughput | no | no |
| GP182_HUMAN | [view interactions] | High throughput | no | no |
| SEM4C_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| SEC62_HUMAN | [view interactions] | High throughput | no | yes |
| GPR17_HUMAN | [view interactions] | High throughput | no | no |
| F234A_HUMAN | [view interactions] | High throughput | no | yes |
| OPALI_HUMAN | [view interactions] | High throughput | no | yes |
| BTNL9_HUMAN | [view interactions] | High throughput | no | no |
| EFNB1_HUMAN | [view interactions] | High throughput | no | yes |
| P2Y10_HUMAN | [view interactions] | High throughput | no | no |
| MTLR_HUMAN | [view interactions] | High throughput | no | no |
| DRG1_HUMAN | [view interactions] | High throughput | no | yes |
| PSA6_HUMAN | [view interactions] | High throughput | no | yes |
| NAA15_HUMAN | [view interactions] | High throughput | no | yes |
| PLOD1_HUMAN | [view interactions] | High throughput | no | yes |
| PLOD2_HUMAN | [view interactions] | High throughput | no | yes |
| TYSD1_HUMAN | [view interactions] | High throughput | no | yes |
| UN45A_HUMAN | [view interactions] | High throughput | no | yes |
| DPPA3_HUMAN | [view interactions] | High throughput | no | no |