CAND2_HUMAN
Evidence for PS localization
Functions
Probable assembly factor of SCF (SKP1-CUL1-F-box protein) E3 ubiquitin ligase complexes that promotes the exchange of the substrate-recognition F-box subunit in SCF complexes, thereby playing a key role in the cellular repertoire of SCF complexes. [View more on UniProt]
Protein features
Binary interactions with known binding regions
To display all evidence describing the interaction with a partner, click on the protein name left to the bars.
Network
Isoforms
Disease-causing germline mutations
No data found.
Linear motifs
No annotated instance was found. To search for linear motifs, use the ELM prediction server.
Fingerprint
Molecular function
No data found.
Biological process
| Term | Name | % | Distance from top the of the tree | Annotated in CAND2_HUMAN |
|---|---|---|---|---|
| GO:0048522 | positive regulation of cellular process | 63.1579 | 4 | yes |
| GO:0010646 | regulation of cell communication | 47.3684 | 4 | no |
| GO:0009889 | regulation of biosynthetic process | 42.1053 | 4 | yes |
| GO:0010468 | regulation of gene expression | 42.1053 | 6 | yes |
| GO:0010556 | regulation of macromolecule biosynthetic process | 42.1053 | 5 | yes |
| GO:0031323 | regulation of cellular metabolic process | 42.1053 | 4 | yes |
| GO:0031326 | regulation of cellular biosynthetic process | 42.1053 | 5 | yes |
| GO:0060255 | regulation of macromolecule metabolic process | 42.1053 | 4 | yes |
| GO:0048523 | negative regulation of cellular process | 42.1053 | 4 | no |
| GO:0009966 | regulation of signal transduction | 42.1053 | 4 | no |
| GO:0009893 | positive regulation of metabolic process | 36.8421 | 4 | yes |
| GO:0010604 | positive regulation of macromolecule metabolic process | 36.8421 | 5 | yes |
| GO:0006996 | organelle organization | 36.8421 | 4 | no |
| GO:0051128 | regulation of cellular component organization | 36.8421 | 4 | no |
| GO:0010647 | positive regulation of cell communication | 36.8421 | 5 | no |
| GO:0023056 | positive regulation of signaling | 36.8421 | 4 | no |
| GO:0036211 | protein modification process | 31.5789 | 4 | yes |
| GO:0043412 | macromolecule modification | 31.5789 | 4 | yes |
| GO:0080090 | regulation of primary metabolic process | 31.5789 | 4 | yes |
| GO:0009890 | negative regulation of biosynthetic process | 31.5789 | 5 | no |
| GO:0009892 | negative regulation of metabolic process | 31.5789 | 4 | no |
| GO:0010558 | negative regulation of macromolecule biosynthetic process | 31.5789 | 6 | no |
| GO:0010605 | negative regulation of macromolecule metabolic process | 31.5789 | 5 | no |
| GO:0031324 | negative regulation of cellular metabolic process | 31.5789 | 5 | no |
| GO:0031327 | negative regulation of cellular biosynthetic process | 31.5789 | 6 | no |
| GO:0032880 | regulation of protein localization | 31.5789 | 5 | no |
| GO:0060341 | regulation of cellular localization | 31.5789 | 4 | no |
| GO:0009967 | positive regulation of signal transduction | 31.5789 | 5 | no |
| GO:0048584 | positive regulation of response to stimulus | 31.5789 | 4 | no |
| GO:0051049 | regulation of transport | 31.5789 | 4 | no |
| GO:0031325 | positive regulation of cellular metabolic process | 26.3158 | 5 | yes |
| GO:0032446 | protein modification by small protein conjugation | 26.3158 | 7 | yes |
| GO:0043687 | post-translational protein modification | 26.3158 | 5 | yes |
| GO:0070647 | protein modification by small protein conjugation or removal | 26.3158 | 6 | yes |
| GO:0008104 | protein localization | 26.3158 | 4 | no |
| GO:0051246 | regulation of protein metabolic process | 26.3158 | 5 | no |
| GO:0010629 | negative regulation of gene expression | 26.3158 | 7 | no |
| GO:0051241 | negative regulation of multicellular organismal process | 26.3158 | 4 | no |
| GO:0030030 | cell projection organization | 26.3158 | 4 | no |
| GO:0051240 | positive regulation of multicellular organismal process | 26.3158 | 4 | no |
| GO:0006355 | regulation of DNA-templated transcription | 21.0526 | 7 | yes |
| GO:0009891 | positive regulation of biosynthetic process | 21.0526 | 5 | yes |
| GO:0010557 | positive regulation of macromolecule biosynthetic process | 21.0526 | 6 | yes |
| GO:0016567 | protein ubiquitination | 21.0526 | 8 | yes |
| GO:0019219 | regulation of nucleobase-containing compound metabolic process | 21.0526 | 5 | yes |
| GO:0022607 | cellular component assembly | 21.0526 | 4 | yes |
| GO:0031328 | positive regulation of cellular biosynthetic process | 21.0526 | 6 | yes |
| GO:0051252 | regulation of RNA metabolic process | 21.0526 | 5 | yes |
| GO:2001141 | regulation of RNA biosynthetic process | 21.0526 | 6 | yes |
| GO:0001817 | regulation of cytokine production | 21.0526 | 4 | no |
| GO:0010648 | negative regulation of cell communication | 21.0526 | 5 | no |
| GO:0023057 | negative regulation of signaling | 21.0526 | 4 | no |
| GO:0031399 | regulation of protein modification process | 21.0526 | 6 | no |
| GO:0031401 | positive regulation of protein modification process | 21.0526 | 7 | no |
| GO:0048585 | negative regulation of response to stimulus | 21.0526 | 4 | no |
| GO:0051247 | positive regulation of protein metabolic process | 21.0526 | 6 | no |
| GO:1902531 | regulation of intracellular signal transduction | 21.0526 | 5 | no |
| GO:1902533 | positive regulation of intracellular signal transduction | 21.0526 | 6 | no |
| GO:0051046 | regulation of secretion | 21.0526 | 5 | no |
| GO:1903530 | regulation of secretion by cell | 21.0526 | 4 | no |
| GO:0008284 | positive regulation of cell population proliferation | 21.0526 | 5 | no |
| GO:0030334 | regulation of cell migration | 21.0526 | 5 | no |
| GO:0042127 | regulation of cell population proliferation | 21.0526 | 4 | no |
| GO:1903829 | positive regulation of protein localization | 21.0526 | 5 | no |
| GO:2000145 | regulation of cell motility | 21.0526 | 4 | no |
| GO:0010975 | regulation of neuron projection development | 21.0526 | 7 | no |
| GO:0022603 | regulation of anatomical structure morphogenesis | 21.0526 | 4 | no |
| GO:0031344 | regulation of cell projection organization | 21.0526 | 5 | no |
| GO:0045595 | regulation of cell differentiation | 21.0526 | 4 | no |
| GO:0120035 | regulation of plasma membrane bounded cell projection organization | 21.0526 | 6 | no |
| GO:0043933 | protein-containing complex organization | 10.5263 | 4 | yes |
| GO:0045893 | positive regulation of DNA-templated transcription | 10.5263 | 8 | yes |
| GO:0045935 | positive regulation of nucleobase-containing compound metabolic process | 10.5263 | 5 | yes |
| GO:0051254 | positive regulation of RNA metabolic process | 10.5263 | 6 | yes |
| GO:0065003 | protein-containing complex assembly | 10.5263 | 5 | yes |
| GO:1902680 | positive regulation of RNA biosynthetic process | 10.5263 | 7 | yes |
Disease
No data found.
All partners
| Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
|---|---|---|---|---|
| CNOT3_HUMAN | [view interactions] | Low throughput | no | yes |
| CUL1_HUMAN | [view interactions] | Low throughput | no | yes |
| TBP_HUMAN | [view interactions] | Low throughput | no | yes |
| UBE3C_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| UB2D1_HUMAN | [view interactions] | Low throughput | no | yes |
| B2L14_HUMAN | [view interactions] | High throughput | no | yes |
| P2RY6_HUMAN | [view interactions] | High throughput | no | no |
| UN93B_HUMAN | [view interactions] | High throughput | no | yes |
| EGFR_HUMAN | [view interactions] | High throughput | no | no |
| KCNQ1_HUMAN | [view interactions] | High throughput | no | yes |
| CAV3_HUMAN | [view interactions] | High throughput | no | no |
| TX101_HUMAN | [view interactions] | High throughput | no | no |
| CIDEB_HUMAN | [view interactions] | High throughput | no | yes |
| SYPH_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FHL2_HUMAN | [view interactions] | High throughput | no | yes |
| STOM_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DNJB6_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GRK5_HUMAN | [view interactions] | High throughput | no | yes |
| CAH9_HUMAN | [view interactions] | High throughput | no | no |
| IQCB1_HUMAN | [view interactions] | High throughput | no | no |
| FBX32_HUMAN | [view interactions] | High throughput | no | no |
| GLP1R_HUMAN | [view interactions] | High throughput | no | no |
| EED_HUMAN | [view interactions] | High throughput | no | yes |
| TMIG3_HUMAN | [view interactions] | High throughput | no | no |
| AA3R_HUMAN | [view interactions] | High throughput | no | no |
| VTI1B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| EFNB2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| BASI_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| TN13B_HUMAN | [view interactions] | High throughput | no | no |
| CD244_HUMAN | [view interactions] | High throughput | no | no |
| PE2R3_HUMAN | [view interactions] | High throughput | no | no |
| SCN2B_HUMAN | [view interactions] | High throughput | no | no |
| AL3A2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| 5HT6R_HUMAN | [view interactions] | High throughput | no | yes |
| CAF1A_HUMAN | [view interactions] | High throughput | no | yes |
| PTPRN_HUMAN | [view interactions] | High throughput | no | yes |
| TPTE_HUMAN | [view interactions] | High throughput | no | no |
| SIGL1_HUMAN | [view interactions] | High throughput | no | no |
| EPHA1_HUMAN | [view interactions] | High throughput | no | yes |
| ACM4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SDC2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NPY2R_HUMAN | [view interactions] | High throughput | no | no |
| 5HT2C_HUMAN | [view interactions] | High throughput | no | no |
| F174A_HUMAN | [view interactions] | High throughput | no | yes |
| LPAR4_HUMAN | [view interactions] | High throughput | no | no |
| ACM3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FZD10_HUMAN | [view interactions] | High throughput | no | no |
| RHG36_HUMAN | [view interactions] | High throughput | no | yes |
| TM108_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FACD2_HUMAN | [view interactions] | High throughput | no | no |
| CXA1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RBX1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| S15A3_HUMAN | [view interactions] | High throughput | no | yes |
| TPTE2_HUMAN | [view interactions] | High throughput | no | no |
| LMBRL_HUMAN | [view interactions] | High throughput | no | no |
| TIF1B_HUMAN | [view interactions] | High throughput | no | yes |
| PKHA4_HUMAN | [view interactions] | High throughput | no | yes |
| CSN5_HUMAN | [view interactions] | High throughput | no | yes |
| DJC15_HUMAN | [view interactions] | High throughput | no | no |
| DNJC1_HUMAN | [view interactions] | High throughput | no | yes |
| DDRGK_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| C5AR1_HUMAN | [view interactions] | High throughput | no | yes |
| NPTN_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SLAF9_HUMAN | [view interactions] | High throughput | no | yes |
| S10A6_HUMAN | [view interactions] | High throughput | no | yes |
| DLK2_HUMAN | [view interactions] | High throughput | no | no |
| CD83_HUMAN | [view interactions] | High throughput | no | yes |
| CXCR4_HUMAN | [view interactions] | High throughput | no | no |
| TACD2_HUMAN | [view interactions] | High throughput | no | no |
| GP182_HUMAN | [view interactions] | High throughput | no | no |
| SEM4C_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| SEC62_HUMAN | [view interactions] | High throughput | no | yes |
| GPR17_HUMAN | [view interactions] | High throughput | no | no |
| F234A_HUMAN | [view interactions] | High throughput | no | yes |
| OPALI_HUMAN | [view interactions] | High throughput | no | yes |
| BTNL9_HUMAN | [view interactions] | High throughput | no | no |
| EFNB1_HUMAN | [view interactions] | High throughput | no | yes |
| P2Y10_HUMAN | [view interactions] | High throughput | no | no |
| MTLR_HUMAN | [view interactions] | High throughput | no | no |
| CUL3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| OVOL2_HUMAN | [view interactions] | High throughput | no | no |
| BAP1_HUMAN | [view interactions] | High throughput | no | yes |
| CCNF_HUMAN | [view interactions] | High throughput | no | no |
| TRI67_HUMAN | [view interactions] | High throughput | no | no |
| CL16A_HUMAN | [view interactions] | High throughput | no | yes |
| DRG1_HUMAN | [view interactions] | High throughput | no | yes |
| PSA6_HUMAN | [view interactions] | High throughput | no | yes |
| NAA15_HUMAN | [view interactions] | High throughput | no | yes |
| PLOD1_HUMAN | [view interactions] | High throughput | no | yes |
| PLOD2_HUMAN | [view interactions] | High throughput | no | yes |
| TYSD1_HUMAN | [view interactions] | High throughput | no | yes |
| UN45A_HUMAN | [view interactions] | High throughput | no | yes |
| DPPA3_HUMAN | [view interactions] | High throughput | no | no |
| RFA1_HUMAN | [view interactions] | High throughput | no | yes |