SDC2_HUMAN
Cell surface proteoglycan which regulates dendritic arbor morphogenesis. [View more on UniProt]
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To display all evidence describing the interaction with a partner, click on the protein name left to the bars.
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No data found.
No annotated instance was found. To search for linear motifs, use the ELM prediction server.
Molecular function
Term | Name | % | Distance from the top of the tree | Annotated in SDC2_HUMAN |
---|---|---|---|---|
GO:0043168 | anion binding | 40.4255 | 4 | no |
GO:0000166 | nucleotide binding | 31.9149 | 4 | no |
GO:0017076 | purine nucleotide binding | 31.9149 | 5 | no |
GO:0032555 | purine ribonucleotide binding | 31.9149 | 4 | no |
GO:0035639 | purine ribonucleoside triphosphate binding | 29.7872 | 4 | no |
GO:0030554 | adenyl nucleotide binding | 21.2766 | 6 | no |
GO:0032559 | adenyl ribonucleotide binding | 21.2766 | 5 | no |
GO:0030165 | PDZ domain binding | 4.2553 | 4 | yes |
Biological process
Term | Name | % | Distance from top the of the tree | Annotated in SDC2_HUMAN |
---|---|---|---|---|
GO:0048522 | positive regulation of cellular process | 68.0851 | 4 | no |
GO:0051128 | regulation of cellular component organization | 46.8085 | 4 | yes |
GO:0048523 | negative regulation of cellular process | 46.8085 | 4 | no |
GO:0022607 | cellular component assembly | 42.5532 | 4 | no |
GO:0010646 | regulation of cell communication | 42.5532 | 4 | no |
GO:0031323 | regulation of cellular metabolic process | 42.5532 | 4 | no |
GO:0060255 | regulation of macromolecule metabolic process | 42.5532 | 4 | no |
GO:0080090 | regulation of primary metabolic process | 42.5532 | 4 | no |
GO:0022603 | regulation of anatomical structure morphogenesis | 36.1702 | 4 | yes |
GO:0006996 | organelle organization | 34.0426 | 4 | no |
GO:0009966 | regulation of signal transduction | 34.0426 | 4 | no |
GO:0051049 | regulation of transport | 34.0426 | 4 | no |
GO:0009893 | positive regulation of metabolic process | 34.0426 | 4 | no |
GO:0048584 | positive regulation of response to stimulus | 34.0426 | 4 | no |
GO:0009892 | negative regulation of metabolic process | 31.9149 | 4 | no |
GO:0009889 | regulation of biosynthetic process | 31.9149 | 4 | no |
GO:0010468 | regulation of gene expression | 31.9149 | 6 | no |
GO:0010556 | regulation of macromolecule biosynthetic process | 31.9149 | 5 | no |
GO:0031326 | regulation of cellular biosynthetic process | 31.9149 | 5 | no |
GO:0010605 | negative regulation of macromolecule metabolic process | 29.7872 | 5 | no |
GO:0051246 | regulation of protein metabolic process | 29.7872 | 5 | no |
GO:0010647 | positive regulation of cell communication | 29.7872 | 5 | no |
GO:0023056 | positive regulation of signaling | 29.7872 | 4 | no |
GO:0051094 | positive regulation of developmental process | 29.7872 | 4 | no |
GO:0019219 | regulation of nucleobase-containing compound metabolic process | 29.7872 | 5 | no |
GO:1902531 | regulation of intracellular signal transduction | 29.7872 | 5 | no |
GO:0010604 | positive regulation of macromolecule metabolic process | 29.7872 | 5 | no |
GO:0030334 | regulation of cell migration | 29.7872 | 5 | no |
GO:2000145 | regulation of cell motility | 29.7872 | 4 | no |
GO:0141124 | intracellular signaling cassette | 27.6596 | 4 | no |
GO:0043067 | regulation of programmed cell death | 27.6596 | 4 | no |
GO:0008104 | protein localization | 27.6596 | 4 | no |
GO:0007264 | small GTPase-mediated signal transduction | 25.5319 | 5 | no |
GO:0042981 | regulation of apoptotic process | 25.5319 | 5 | no |
GO:0060627 | regulation of vesicle-mediated transport | 25.5319 | 4 | no |
GO:0031324 | negative regulation of cellular metabolic process | 25.5319 | 5 | no |
GO:0031325 | positive regulation of cellular metabolic process | 25.5319 | 5 | no |
GO:0051240 | positive regulation of multicellular organismal process | 25.5319 | 4 | no |
GO:0051252 | regulation of RNA metabolic process | 25.5319 | 5 | no |
GO:0030155 | regulation of cell adhesion | 25.5319 | 4 | no |
GO:0030335 | positive regulation of cell migration | 25.5319 | 6 | no |
GO:0040017 | positive regulation of locomotion | 25.5319 | 4 | no |
GO:2000147 | positive regulation of cell motility | 25.5319 | 5 | no |
GO:0042127 | regulation of cell population proliferation | 25.5319 | 4 | no |
GO:0030030 | cell projection organization | 23.4043 | 4 | yes |
GO:0007010 | cytoskeleton organization | 23.4043 | 5 | no |
GO:0044087 | regulation of cellular component biogenesis | 23.4043 | 4 | no |
GO:0033043 | regulation of organelle organization | 23.4043 | 5 | no |
GO:0043933 | protein-containing complex organization | 23.4043 | 4 | no |
GO:0006796 | phosphate-containing compound metabolic process | 23.4043 | 4 | no |
GO:0009894 | regulation of catabolic process | 23.4043 | 4 | no |
GO:0048585 | negative regulation of response to stimulus | 23.4043 | 4 | no |
GO:0051046 | regulation of secretion | 23.4043 | 5 | no |
GO:0009967 | positive regulation of signal transduction | 23.4043 | 5 | no |
GO:0051247 | positive regulation of protein metabolic process | 23.4043 | 6 | no |
GO:0031344 | regulation of cell projection organization | 21.2766 | 5 | yes |
GO:0032880 | regulation of protein localization | 21.2766 | 5 | no |
GO:0060341 | regulation of cellular localization | 21.2766 | 4 | no |
GO:0051130 | positive regulation of cellular component organization | 21.2766 | 5 | no |
GO:0065003 | protein-containing complex assembly | 21.2766 | 5 | no |
GO:0097435 | supramolecular fiber organization | 21.2766 | 4 | no |
GO:0009968 | negative regulation of signal transduction | 21.2766 | 5 | no |
GO:0010648 | negative regulation of cell communication | 21.2766 | 5 | no |
GO:0023057 | negative regulation of signaling | 21.2766 | 4 | no |
GO:0043066 | negative regulation of apoptotic process | 21.2766 | 6 | no |
GO:0043069 | negative regulation of programmed cell death | 21.2766 | 5 | no |
GO:0051050 | positive regulation of transport | 21.2766 | 4 | no |
GO:1903530 | regulation of secretion by cell | 21.2766 | 4 | no |
GO:0009890 | negative regulation of biosynthetic process | 21.2766 | 5 | no |
GO:2000026 | regulation of multicellular organismal development | 21.2766 | 4 | no |
GO:0002684 | positive regulation of immune system process | 21.2766 | 4 | no |
GO:0061024 | membrane organization | 21.2766 | 4 | no |
GO:0010632 | regulation of epithelial cell migration | 21.2766 | 4 | no |
GO:0120035 | regulation of plasma membrane bounded cell projection organization | 19.1489 | 6 | yes |
GO:0010975 | regulation of neuron projection development | 10.6383 | 7 | yes |
GO:0048812 | neuron projection morphogenesis | 6.3830 | 5 | yes |
GO:0048813 | dendrite morphogenesis | 6.3830 | 6 | yes |
GO:0048814 | regulation of dendrite morphogenesis | 6.3830 | 5 | yes |
GO:0050773 | regulation of dendrite development | 6.3830 | 4 | yes |
GO:0120039 | plasma membrane bounded cell projection morphogenesis | 6.3830 | 4 | yes |
Disease
No data found.
Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
---|---|---|---|---|
NF1_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
CSKP_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
SDC2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
FGF2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
SDCB1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
SDC4_HUMAN | [view interactions] | Low throughput | no | yes |
RASA1_HUMAN | [view interactions] | Low throughput | no | yes |
SDC3_HUMAN | [view interactions] | Low throughput | no | yes |
PCOC1_HUMAN | [view interactions] | Low throughput | no | yes |
TIAM1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
ITB4_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
E41L1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
ITPR1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
LAMA3_HUMAN | [view interactions] | Low throughput | no | no |
CSF2R_HUMAN | [view interactions] | Low throughput | no | no |
EZRI_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
KALM_HUMAN | [view interactions] | Low throughput | no | no |
HGF_HUMAN | [view interactions] | Low throughput | no | yes |
CSF2_HUMAN | [view interactions] | Low throughput | no | no |
REG3A_HUMAN | [view interactions] | Low throughput | no | no |
FINC_HUMAN | [view interactions] | Low throughput | no | yes |
KPCA_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
KPCB_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
KPCG_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
CP2CI_HUMAN | [view interactions] | High throughput | no | no |
A1AT_HUMAN | [view interactions] | High throughput | no | no |
PP2BC_HUMAN | [view interactions] | High throughput | no | yes |
BAG6_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
RIPK4_HUMAN | [view interactions] | High throughput | no | no |
IFIX_HUMAN | [view interactions] | High throughput | no | no |
EFNB2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
H2A1_HUMAN | [view interactions] | High throughput | no | yes |
TMM11_HUMAN | [view interactions] | High throughput | no | no |
FGFR2_HUMAN | [view interactions] | High throughput | no | yes |
ECHA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
PI4KA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
ECHB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
XPC_HUMAN | [view interactions] | High throughput | no | yes |
DHRS2_HUMAN | [view interactions] | High throughput | no | no |
MTR1L_HUMAN | [view interactions] | High throughput | no | no |
ZN460_HUMAN | [view interactions] | High throughput | no | no |
RN213_HUMAN | [view interactions] | High throughput | no | yes |
HEAT6_HUMAN | [view interactions] | High throughput | no | no |
EXOC3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
NBEL1_HUMAN | [view interactions] | High throughput | no | yes |
SULF1_HUMAN | [view interactions] | High throughput | no | no |
KLHL7_HUMAN | [view interactions] | High throughput | no | yes |
FGRL1_HUMAN | [view interactions] | High throughput | no | yes |
SNX33_HUMAN | [view interactions] | High throughput | no | yes |
CTR3_HUMAN | [view interactions] | High throughput | no | no |
TM186_HUMAN | [view interactions] | High throughput | no | no |
TEFM_HUMAN | [view interactions] | High throughput | no | no |
S10AD_HUMAN | [view interactions] | High throughput | no | yes |
SEM3C_HUMAN | [view interactions] | High throughput | no | no |
PRD10_HUMAN | [view interactions] | High throughput | no | yes |
GMEB2_HUMAN | [view interactions] | High throughput | no | yes |
VANG2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
FARP1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
TF3C3_HUMAN | [view interactions] | High throughput | no | no |
GP183_HUMAN | [view interactions] | High throughput | no | yes |
LIPG_HUMAN | [view interactions] | High throughput | no | no |
FGF1_HUMAN | [view interactions] | High throughput | no | no |
NCBP3_HUMAN | [view interactions] | High throughput | no | yes |
PDPK1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
CAMKV_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
GPR37_HUMAN | [view interactions] | High throughput | no | no |
GRN_HUMAN | [view interactions] | High throughput | no | no |
ESRP1_HUMAN | [view interactions] | High throughput | no | yes |
WFS1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
RNF11_HUMAN | [view interactions] | High throughput | no | yes |
SPRE1_HUMAN | [view interactions] | High throughput | no | yes |
CSK22_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
SDC1_HUMAN | [view interactions] | High throughput | no | no |
MYB_HUMAN | [view interactions] | High throughput | no | yes |
FHI1B_HUMAN | [view interactions] | High throughput | no | yes |
KCNK3_HUMAN | [view interactions] | High throughput | no | no |
GRIP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
ASPH_HUMAN | [view interactions] | High throughput | no | yes |
SPAG6_HUMAN | [view interactions] | High throughput | no | no |
ELAV1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
VMAT1_HUMAN | [view interactions] | High throughput | no | no |
ATX3_HUMAN | [view interactions] | High throughput | no | yes |
RPAB2_HUMAN | [view interactions] | High throughput | no | yes |
LAP2A_HUMAN | [view interactions] | High throughput | no | yes |
CBX4_HUMAN | [view interactions] | High throughput | no | yes |
HNRPQ_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
CBX1_HUMAN | [view interactions] | High throughput | no | yes |
TNKS1_HUMAN | [view interactions] | High throughput | no | yes |
TPX2_HUMAN | [view interactions] | High throughput | no | yes |
GMEB1_HUMAN | [view interactions] | High throughput | no | yes |
PARP2_HUMAN | [view interactions] | High throughput | no | yes |
DOP2_HUMAN | [view interactions] | High throughput | no | yes |
AMPD2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
TM192_HUMAN | [view interactions] | High throughput | no | yes |
SNX18_HUMAN | [view interactions] | High throughput | no | no |
TF3C2_HUMAN | [view interactions] | High throughput | no | no |
VANG1_HUMAN | [view interactions] | High throughput | no | no |
FGFR3_HUMAN | [view interactions] | High throughput | no | yes |
SULF2_HUMAN | [view interactions] | High throughput | no | yes |
CKAP5_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
OSBL8_HUMAN | [view interactions] | High throughput | no | yes |
ZNF92_HUMAN | [view interactions] | High throughput | no | no |
CNDH2_HUMAN | [view interactions] | High throughput | no | no |
CAND2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
TF3C1_HUMAN | [view interactions] | High throughput | no | yes |
SMC2_HUMAN | [view interactions] | High throughput | no | yes |
TNIP2_HUMAN | [view interactions] | High throughput | no | yes |
VIR_HUMAN | [view interactions] | High throughput | no | yes |
CHM4B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
EVA1B_HUMAN | [view interactions] | High throughput | no | yes |
FGF4_HUMAN | [view interactions] | High throughput | no | no |
CHD1L_HUMAN | [view interactions] | High throughput | no | yes |
MON2_HUMAN | [view interactions] | High throughput | no | no |
SYT1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
LYRIC_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
ELMO3_HUMAN | [view interactions] | High throughput | no | yes |
TSNA1_HUMAN | [view interactions] | High throughput | no | yes |
PLCD3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
MAN1_HUMAN | [view interactions] | High throughput | no | yes |
AT2A3_HUMAN | [view interactions] | High throughput | no | yes |
DOCK1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
DOCK5_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
EXOC2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
ORC4_HUMAN | [view interactions] | High throughput | no | yes |
TZAP_HUMAN | [view interactions] | High throughput | no | no |
GT2D1_HUMAN | [view interactions] | High throughput | no | yes |
TEX2_HUMAN | [view interactions] | High throughput | no | yes |
HIP1R_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
HEAT3_HUMAN | [view interactions] | High throughput | no | yes |
DDX24_HUMAN | [view interactions] | High throughput | no | yes |
H2A2B_HUMAN | [view interactions] | High throughput | no | yes |
TSYL1_HUMAN | [view interactions] | High throughput | no | yes |
H2AY_HUMAN | [view interactions] | High throughput | no | yes |
PLPL6_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
SRC_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
LYAR_HUMAN | [view interactions] | High throughput | no | no |
KCNN4_HUMAN | [view interactions] | High throughput | no | no |
ELAP2_HUMAN | [view interactions] | High throughput | no | no |
HKDC1_HUMAN | [view interactions] | High throughput | no | no |
RAC1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
RAC2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
RAC3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
RHOB_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
RHOA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
TNIP1_HUMAN | [view interactions] | High throughput | no | yes |
B3GA1_HUMAN | [view interactions] | High throughput | no | yes |
CACO2_HUMAN | [view interactions] | High throughput | no | yes |
OPTN_HUMAN | [view interactions] | High throughput | no | yes |
SQSTM_HUMAN | [view interactions] | High throughput | no | yes |
TAXB1_HUMAN | [view interactions] | High throughput | no | yes |
CCNF_HUMAN | [view interactions] | High throughput | no | no |