KPCA_HUMAN
Calcium-activated, phospholipid- and diacylglycerol (DAG)-dependent serine/threonine-protein kinase that is involved in positive and negative regulation of cell proliferation, apoptosis, differentiation, migration and adhesion, tumorigenesis, cardiac hypertrophy, angiogenesis, platelet function and inflammation, by directly phosphorylating targets such as RAF1, BCL2, CSPG4, TNNT2/CTNT, or activating signaling cascade involving MAPK1/3 (ERK1/2) and RAP1GAP. Involved in cell proliferation and cell growth arrest by positive and negative regulation of the cell cycle. Can promote cell growth by phosphorylating and activating RAF1, which mediates the activation of the MAPK/ERK signaling cascade, and/or by up-regulating CDKN1A, which facilitates active cyclin-dependent kinase (CDK) complex formation in glioma cells. In intestinal cells stimulated by the phorbol ester PMA, can trigger a cell cycle arrest program which is associated with the accumulation of the hyper-phosphorylated growth-suppressive form of RB1 and induction of the CDK inhibitors CDKN1A and CDKN1B. Exhibits anti-apoptotic function in glioma cells and protects them from apoptosis by suppressing the p53/TP53-mediated activation of IGFBP3, and in leukemia cells mediates anti-apoptotic action by phosphorylating BCL2. During macrophage differentiation induced by macrophage colony-stimulating factor (CSF1), is translocated to the nucleus and is associated with macrophage development. After wounding, translocates from focal contacts to lamellipodia and participates in the modulation of desmosomal adhesion. Plays a role in cell motility by phosphorylating CSPG4, which induces association of CSPG4 with extensive lamellipodia at the cell periphery and polarization of the cell accompanied by increases in cell motility. During chemokine-induced CD4(+) T cell migration, phosphorylates CDC42-guanine exchange factor DOCK8 resulting in its dissociation from LRCH1 and the activation of GTPase CDC42 (PubMed). Is highly expressed in a number of cancer cells where it can act as a tumor promoter and is implicated in malignant phenotypes of several tumors such as gliomas and breast cancers. Negatively regulates myocardial contractility and positively regulates angiogenesis, platelet aggregation and thrombus formation in arteries. Mediates hypertrophic growth of neonatal cardiomyocytes, in part through a MAPK1/3 (ERK1/2)-dependent signaling pathway, and upon PMA treatment, is required to induce cardiomyocyte hypertrophy up to heart failure and death, by increasing protein synthesis, protein-DNA ratio and cell surface area. Regulates cardiomyocyte function by phosphorylating cardiac troponin T (TNNT2/CTNT), which induces significant reduction in actomyosin ATPase activity, myofilament calcium sensitivity and myocardial contractility. In angiogenesis, is required for full endothelial cell migration, adhesion to vitronectin (VTN), and vascular endothelial growth factor A (VEGFA)-dependent regulation of kinase activation and vascular tube formation. Involved in the stabilization of VEGFA mRNA at post-transcriptional level and mediates VEGFA-induced cell proliferation. In the regulation of calcium-induced platelet aggregation, mediates signals from the CD36/GP4 receptor for granule release, and activates the integrin heterodimer ITGA2B-ITGB3 through the RAP1GAP pathway for adhesion. During response to lipopolysaccharides (LPS), may regulate selective LPS-induced macrophage functions involved in host defense and inflammation. But in some inflammatory responses, may negatively regulate NF-kappa-B-induced genes, through IL1A-dependent induction of NF-kappa-B inhibitor alpha (NFKBIA/IKBA). Upon stimulation with 12-O-tetradecanoylphorbol-13-acetate (TPA), phosphorylates EIF4G1, which modulates EIF4G1 binding to MKNK1 and may be involved in the regulation of EIF4E phosphorylation. Phosphorylates KIT, leading to inhibition of KIT activity. Phosphorylates ATF2 which promotes cooperation between ATF2 and JUN, activating transcription. Phosphorylates SOCS2 at Ser-52 facilitating its ubiquitination and proteosomal degradation . [View more on UniProt]
Interacting region for partners were not defined.
No data found.
No annotated instance was found. To search for linear motifs, use the ELM prediction server.
Molecular function
Term | Name | % | Distance from the top of the tree | Annotated in KPCA_HUMAN |
---|---|---|---|---|
GO:0017076 | purine nucleotide binding | 32.3171 | 4 | yes |
GO:0032555 | purine ribonucleotide binding | 32.3171 | 4 | yes |
GO:0035639 | purine ribonucleoside triphosphate binding | 31.7073 | 4 | yes |
GO:0019900 | kinase binding | 31.0976 | 4 | no |
GO:0019901 | protein kinase binding | 29.2683 | 5 | no |
GO:0046872 | metal ion binding | 28.0488 | 4 | yes |
GO:0030554 | adenyl nucleotide binding | 26.8293 | 5 | yes |
GO:0032559 | adenyl ribonucleotide binding | 26.8293 | 5 | yes |
GO:0005524 | ATP binding | 26.2195 | 5 | yes |
GO:0016301 | kinase activity | 17.6829 | 4 | yes |
GO:0016773 | phosphotransferase activity, alcohol group as acceptor | 17.0732 | 4 | yes |
GO:0004712 | protein serine/threonine/tyrosine kinase activity | 15.2439 | 4 | yes |
GO:0004674 | protein serine/threonine kinase activity | 13.4146 | 4 | yes |
GO:0106310 | protein serine kinase activity | 11.5854 | 4 | yes |
GO:0046914 | transition metal ion binding | 6.0976 | 5 | yes |
GO:0004697 | protein kinase C activity | 4.2683 | 5 | yes |
GO:0004698 | calcium-dependent protein kinase C activity | 4.2683 | 6 | yes |
GO:0008270 | zinc ion binding | 4.2683 | 6 | yes |
GO:0009931 | calcium-dependent protein serine/threonine kinase activity | 4.2683 | 5 | yes |
GO:0010857 | calcium-dependent protein kinase activity | 4.2683 | 4 | yes |
GO:0035173 | histone kinase activity | 2.4390 | 4 | yes |
GO:0035184 | histone threonine kinase activity | 1.8293 | 5 | yes |
GO:0035403 | histone kinase activity (H3-T6 specific) | 1.8293 | 6 | yes |
Biological process
Term | Name | % | Distance from top the of the tree | Annotated in KPCA_HUMAN |
---|---|---|---|---|
GO:0048522 | positive regulation of cellular process | 65.2439 | 4 | yes |
GO:0048523 | negative regulation of cellular process | 60.9756 | 4 | yes |
GO:0060255 | regulation of macromolecule metabolic process | 58.5366 | 4 | yes |
GO:0010646 | regulation of cell communication | 56.7073 | 4 | yes |
GO:0080090 | regulation of primary metabolic process | 56.0976 | 4 | yes |
GO:0051171 | regulation of nitrogen compound metabolic process | 55.4878 | 4 | yes |
GO:0031323 | regulation of cellular metabolic process | 54.8780 | 4 | yes |
GO:0051246 | regulation of protein metabolic process | 48.7805 | 5 | no |
GO:0009966 | regulation of signal transduction | 48.1707 | 4 | yes |
GO:0009893 | positive regulation of metabolic process | 45.7317 | 4 | no |
GO:0051049 | regulation of transport | 43.9024 | 4 | no |
GO:0010604 | positive regulation of macromolecule metabolic process | 42.6829 | 5 | no |
GO:0051128 | regulation of cellular component organization | 40.8537 | 4 | no |
GO:0010468 | regulation of gene expression | 40.8537 | 5 | yes |
GO:0031325 | positive regulation of cellular metabolic process | 38.4146 | 5 | no |
GO:0031399 | regulation of protein modification process | 38.4146 | 6 | no |
GO:0051173 | positive regulation of nitrogen compound metabolic process | 38.4146 | 5 | no |
GO:0023056 | positive regulation of signaling | 37.1951 | 4 | yes |
GO:0010647 | positive regulation of cell communication | 36.5854 | 5 | yes |
GO:1902531 | regulation of intracellular signal transduction | 36.5854 | 5 | yes |
GO:0071310 | cellular response to organic substance | 35.9756 | 4 | no |
GO:0019220 | regulation of phosphate metabolic process | 35.3659 | 6 | no |
GO:0051174 | regulation of phosphorus metabolic process | 35.3659 | 5 | no |
GO:0051247 | positive regulation of protein metabolic process | 35.3659 | 6 | no |
GO:0010941 | regulation of cell death | 34.7561 | 4 | yes |
GO:0048584 | positive regulation of response to stimulus | 34.7561 | 4 | yes |
GO:0009892 | negative regulation of metabolic process | 34.7561 | 4 | no |
GO:0022607 | cellular component assembly | 33.5366 | 4 | yes |
GO:0043085 | positive regulation of catalytic activity | 33.5366 | 4 | no |
GO:0008104 | protein localization | 32.9268 | 4 | no |
GO:0042325 | regulation of phosphorylation | 32.9268 | 7 | no |
GO:0010605 | negative regulation of macromolecule metabolic process | 32.9268 | 5 | no |
GO:0009889 | regulation of biosynthetic process | 32.9268 | 4 | no |
GO:0006996 | organelle organization | 32.9268 | 4 | no |
GO:0042981 | regulation of apoptotic process | 32.3171 | 6 | yes |
GO:0043067 | regulation of programmed cell death | 32.3171 | 5 | yes |
GO:0001932 | regulation of protein phosphorylation | 31.7073 | 7 | no |
GO:0031326 | regulation of cellular biosynthetic process | 31.7073 | 5 | no |
GO:0010556 | regulation of macromolecule biosynthetic process | 31.0976 | 5 | no |
GO:0019219 | regulation of nucleobase-containing compound metabolic process | 29.8780 | 5 | yes |
GO:0051094 | positive regulation of developmental process | 29.8780 | 4 | yes |
GO:0051172 | negative regulation of nitrogen compound metabolic process | 29.8780 | 5 | no |
GO:0051240 | positive regulation of multicellular organismal process | 29.2683 | 4 | yes |
GO:0031324 | negative regulation of cellular metabolic process | 28.0488 | 5 | no |
GO:0009967 | positive regulation of signal transduction | 28.0488 | 5 | yes |
GO:0045595 | regulation of cell differentiation | 27.4390 | 4 | yes |
GO:0051338 | regulation of transferase activity | 27.4390 | 4 | no |
GO:0051336 | regulation of hydrolase activity | 26.8293 | 4 | no |
GO:0071702 | organic substance transport | 26.8293 | 4 | no |
GO:0006796 | phosphate-containing compound metabolic process | 26.8293 | 4 | yes |
GO:0036211 | protein modification process | 26.2195 | 4 | yes |
GO:0042127 | regulation of cell population proliferation | 26.2195 | 4 | yes |
GO:0043412 | macromolecule modification | 26.2195 | 4 | yes |
GO:0060548 | negative regulation of cell death | 26.2195 | 5 | yes |
GO:0010243 | response to organonitrogen compound | 26.2195 | 4 | no |
GO:0043066 | negative regulation of apoptotic process | 25.6098 | 7 | yes |
GO:0043069 | negative regulation of programmed cell death | 25.6098 | 6 | yes |
GO:0051050 | positive regulation of transport | 25.6098 | 4 | no |
GO:0060341 | regulation of cellular localization | 25.6098 | 4 | no |
GO:0051252 | regulation of RNA metabolic process | 25.0000 | 5 | yes |
GO:2000145 | regulation of cell motility | 25.0000 | 4 | yes |
GO:0010562 | positive regulation of phosphorus metabolic process | 25.0000 | 6 | no |
GO:0031401 | positive regulation of protein modification process | 25.0000 | 7 | no |
GO:0042327 | positive regulation of phosphorylation | 25.0000 | 8 | no |
GO:0045937 | positive regulation of phosphate metabolic process | 25.0000 | 7 | no |
GO:0043549 | regulation of kinase activity | 24.3902 | 5 | no |
GO:0071705 | nitrogen compound transport | 24.3902 | 4 | no |
GO:0050804 | modulation of chemical synaptic transmission | 24.3902 | 5 | no |
GO:0099177 | regulation of trans-synaptic signaling | 24.3902 | 4 | no |
GO:0033043 | regulation of organelle organization | 24.3902 | 5 | no |
GO:1901701 | cellular response to oxygen-containing compound | 24.3902 | 4 | no |
GO:0030334 | regulation of cell migration | 23.7805 | 5 | yes |
GO:0001934 | positive regulation of protein phosphorylation | 23.7805 | 8 | no |
GO:0051248 | negative regulation of protein metabolic process | 23.7805 | 6 | no |
GO:0051130 | positive regulation of cellular component organization | 23.7805 | 5 | no |
GO:0010648 | negative regulation of cell communication | 23.7805 | 5 | no |
GO:0023057 | negative regulation of signaling | 23.7805 | 4 | no |
GO:0032880 | regulation of protein localization | 23.1707 | 5 | no |
GO:2000026 | regulation of multicellular organismal development | 22.5610 | 4 | yes |
GO:0045859 | regulation of protein kinase activity | 22.5610 | 6 | no |
GO:0016192 | vesicle-mediated transport | 22.5610 | 4 | no |
GO:0006355 | regulation of DNA-templated transcription | 22.5610 | 6 | no |
GO:1903506 | regulation of nucleic acid-templated transcription | 22.5610 | 7 | no |
GO:2001141 | regulation of RNA biosynthetic process | 22.5610 | 6 | no |
GO:0080134 | regulation of response to stress | 22.5610 | 4 | no |
GO:0048585 | negative regulation of response to stimulus | 22.5610 | 4 | no |
GO:0044087 | regulation of cellular component biogenesis | 21.9512 | 4 | yes |
GO:1902533 | positive regulation of intracellular signal transduction | 21.9512 | 6 | yes |
GO:0022603 | regulation of anatomical structure morphogenesis | 21.3415 | 4 | yes |
GO:0051347 | positive regulation of transferase activity | 21.3415 | 5 | no |
GO:0015031 | protein transport | 21.3415 | 4 | no |
GO:0010628 | positive regulation of gene expression | 20.7317 | 6 | no |
GO:0014070 | response to organic cyclic compound | 20.7317 | 4 | no |
GO:0007010 | cytoskeleton organization | 20.7317 | 5 | no |
GO:0009894 | regulation of catabolic process | 20.7317 | 4 | yes |
GO:0045597 | positive regulation of cell differentiation | 20.1220 | 5 | yes |
GO:0030030 | cell projection organization | 20.1220 | 4 | no |
GO:0051345 | positive regulation of hydrolase activity | 20.1220 | 5 | no |
GO:0016310 | phosphorylation | 19.5122 | 5 | yes |
GO:0006468 | protein phosphorylation | 18.9024 | 5 | yes |
GO:0030335 | positive regulation of cell migration | 18.2927 | 6 | yes |
GO:0040017 | positive regulation of locomotion | 18.2927 | 4 | yes |
GO:2000147 | positive regulation of cell motility | 18.2927 | 5 | yes |
GO:0008284 | positive regulation of cell population proliferation | 17.6829 | 5 | yes |
GO:0030155 | regulation of cell adhesion | 17.0732 | 4 | yes |
GO:0043408 | regulation of MAPK cascade | 17.0732 | 6 | yes |
GO:0002684 | positive regulation of immune system process | 17.0732 | 4 | yes |
GO:0018193 | peptidyl-amino acid modification | 16.4634 | 5 | yes |
GO:0051726 | regulation of cell cycle | 16.4634 | 4 | yes |
GO:0032101 | regulation of response to external stimulus | 15.8537 | 4 | yes |
GO:0034330 | cell junction organization | 15.8537 | 4 | yes |
GO:0044057 | regulation of system process | 15.8537 | 4 | yes |
GO:0034097 | response to cytokine | 14.0244 | 4 | yes |
GO:0031329 | regulation of cellular catabolic process | 13.4146 | 5 | yes |
GO:0044089 | positive regulation of cellular component biogenesis | 12.8049 | 5 | yes |
GO:0045785 | positive regulation of cell adhesion | 12.1951 | 5 | yes |
GO:0050865 | regulation of cell activation | 12.1951 | 4 | yes |
GO:0061024 | membrane organization | 12.1951 | 4 | yes |
GO:0034329 | cell junction assembly | 11.5854 | 5 | yes |
GO:0043410 | positive regulation of MAPK cascade | 11.5854 | 7 | yes |
GO:0018105 | peptidyl-serine phosphorylation | 10.3659 | 6 | yes |
GO:0018209 | peptidyl-serine modification | 10.3659 | 6 | yes |
GO:0022407 | regulation of cell-cell adhesion | 10.3659 | 5 | yes |
GO:0032103 | positive regulation of response to external stimulus | 10.3659 | 5 | yes |
GO:0070372 | regulation of ERK1 and ERK2 cascade | 10.3659 | 7 | yes |
GO:0010608 | post-transcriptional regulation of gene expression | 9.1463 | 6 | yes |
GO:0010632 | regulation of epithelial cell migration | 8.5366 | 4 | yes |
GO:0090257 | regulation of muscle system process | 8.5366 | 5 | yes |
GO:0045216 | cell-cell junction organization | 7.9268 | 5 | yes |
GO:0010634 | positive regulation of epithelial cell migration | 7.3171 | 5 | yes |
GO:0045765 | regulation of angiogenesis | 7.3171 | 5 | yes |
GO:0045787 | positive regulation of cell cycle | 7.3171 | 5 | yes |
GO:0050678 | regulation of epithelial cell proliferation | 7.3171 | 5 | yes |
GO:0070374 | positive regulation of ERK1 and ERK2 cascade | 7.3171 | 8 | yes |
GO:1901342 | regulation of vasculature development | 7.3171 | 5 | yes |
GO:0010594 | regulation of endothelial cell migration | 6.7073 | 5 | yes |
GO:1903706 | regulation of hemopoiesis | 6.7073 | 4 | yes |
GO:0002831 | regulation of response to biotic stimulus | 6.7073 | 4 | yes |
GO:0050679 | positive regulation of epithelial cell proliferation | 6.0976 | 6 | yes |
GO:0007346 | regulation of mitotic cell cycle | 6.0976 | 5 | yes |
GO:0010595 | positive regulation of endothelial cell migration | 5.4878 | 6 | yes |
GO:0018107 | peptidyl-threonine phosphorylation | 5.4878 | 6 | yes |
GO:0018210 | peptidyl-threonine modification | 5.4878 | 6 | yes |
GO:0045766 | positive regulation of angiogenesis | 5.4878 | 6 | yes |
GO:1904018 | positive regulation of vasculature development | 5.4878 | 5 | yes |
GO:0007043 | cell-cell junction assembly | 5.4878 | 6 | yes |
GO:0008277 | regulation of G protein-coupled receptor signaling pathway | 5.4878 | 5 | yes |
GO:0045637 | regulation of myeloid cell differentiation | 4.8780 | 5 | yes |
GO:1902105 | regulation of leukocyte differentiation | 4.8780 | 5 | yes |
GO:0001936 | regulation of endothelial cell proliferation | 4.2683 | 6 | yes |
GO:0001938 | positive regulation of endothelial cell proliferation | 4.2683 | 7 | yes |
GO:0010543 | regulation of platelet activation | 4.2683 | 5 | yes |
GO:0022411 | cellular component disassembly | 3.6585 | 4 | yes |
GO:0034110 | regulation of homotypic cell-cell adhesion | 3.6585 | 6 | yes |
GO:0043535 | regulation of blood vessel endothelial cell migration | 3.6585 | 6 | yes |
GO:0045931 | positive regulation of mitotic cell cycle | 3.6585 | 6 | yes |
GO:0070555 | response to interleukin-1 | 3.6585 | 5 | yes |
GO:0090330 | regulation of platelet aggregation | 3.6585 | 6 | yes |
GO:1903311 | regulation of mRNA metabolic process | 3.6585 | 6 | yes |
GO:0002833 | positive regulation of response to biotic stimulus | 3.6585 | 5 | yes |
GO:0034103 | regulation of tissue remodeling | 3.0488 | 4 | yes |
GO:0043488 | regulation of mRNA stability | 3.0488 | 4 | yes |
GO:0043536 | positive regulation of blood vessel endothelial cell migration | 3.0488 | 7 | yes |
GO:0046850 | regulation of bone remodeling | 3.0488 | 5 | yes |
GO:0061013 | regulation of mRNA catabolic process | 3.0488 | 6 | yes |
GO:1902107 | positive regulation of leukocyte differentiation | 3.0488 | 6 | yes |
GO:1903708 | positive regulation of hemopoiesis | 3.0488 | 5 | yes |
GO:0002761 | regulation of myeloid leukocyte differentiation | 3.0488 | 6 | yes |
GO:0034350 | regulation of glial cell apoptotic process | 2.4390 | 7 | yes |
GO:0045639 | positive regulation of myeloid cell differentiation | 2.4390 | 6 | yes |
GO:0010611 | regulation of cardiac muscle hypertrophy | 1.8293 | 5 | yes |
GO:0014743 | regulation of muscle hypertrophy | 1.8293 | 6 | yes |
GO:0030397 | membrane disassembly | 1.8293 | 5 | yes |
GO:0034351 | negative regulation of glial cell apoptotic process | 1.8293 | 8 | yes |
GO:0043502 | regulation of muscle adaptation | 1.8293 | 4 | yes |
GO:0051081 | nuclear membrane disassembly | 1.8293 | 6 | yes |
GO:0071763 | nuclear membrane organization | 1.8293 | 5 | yes |
GO:0002934 | desmosome organization | 1.8293 | 6 | yes |
GO:0007077 | mitotic nuclear membrane disassembly | 1.8293 | 4 | yes |
GO:0010613 | positive regulation of cardiac muscle hypertrophy | 1.2195 | 6 | yes |
GO:0014742 | positive regulation of muscle hypertrophy | 1.2195 | 5 | yes |
GO:0031664 | regulation of lipopolysaccharide-mediated signaling pathway | 1.2195 | 5 | yes |
GO:0031666 | positive regulation of lipopolysaccharide-mediated signaling pathway | 1.2195 | 6 | yes |
GO:0045649 | regulation of macrophage differentiation | 1.2195 | 7 | yes |
GO:0045651 | positive regulation of macrophage differentiation | 1.2195 | 8 | yes |
GO:0045745 | positive regulation of G protein-coupled receptor signaling pathway | 1.2195 | 6 | yes |
GO:0045780 | positive regulation of bone resorption | 1.2195 | 4 | yes |
GO:0106070 | regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway | 1.2195 | 6 | yes |
GO:0106071 | positive regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway | 1.2195 | 7 | yes |
GO:2000705 | regulation of dense core granule biogenesis | 1.2195 | 5 | yes |
GO:2000707 | positive regulation of dense core granule biogenesis | 1.2195 | 6 | yes |
GO:0002159 | desmosome assembly | 1.2195 | 7 | yes |
GO:0002763 | positive regulation of myeloid leukocyte differentiation | 1.2195 | 7 | yes |
Disease
Term | Name | % | Distance from top the of the tree | Annotated in KPCA_HUMAN |
---|---|---|---|---|
DOID:114 | heart disease | 3.0488 | 3 | no |
DOID:331 | central nervous system disease | 3.0488 | 3 | no |
DOID:0060038 | specific developmental disorder | 2.4390 | 3 | no |
DOID:1059 | intellectual disability | 2.4390 | 4 | no |
DOID:10595 | Charcot-Marie-Tooth disease | 2.4390 | 6 | no |
DOID:440 | neuromuscular disease | 2.4390 | 5 | no |
DOID:574 | peripheral nervous system disease | 2.4390 | 3 | no |
DOID:870 | neuropathy | 2.4390 | 4 | no |
DOID:0050700 | cardiomyopathy | 2.4390 | 4 | no |
DOID:0060036 | intrinsic cardiomyopathy | 2.4390 | 5 | no |
DOID:936 | brain disease | 1.8293 | 4 | no |
DOID:0050155 | sensory system disease | 1.2195 | 3 | no |
DOID:0050888 | syndromic intellectual disability | 1.2195 | 5 | no |
DOID:0060309 | syndromic X-linked intellectual disability | 1.2195 | 6 | no |
DOID:2843 | long QT syndrome | 1.2195 | 6 | no |
DOID:0060307 | autosomal dominant intellectual developmental disorder | 1.2195 | 5 | no |
DOID:0050539 | Charcot-Marie-Tooth disease type 2 | 1.2195 | 7 | no |
DOID:1289 | neurodegenerative disease | 1.2195 | 4 | no |
DOID:231 | motor neuron disease | 1.2195 | 5 | no |
DOID:10579 | leukodystrophy | 1.2195 | 6 | no |
DOID:1443 | cerebral degeneration | 1.2195 | 5 | no |
DOID:0050557 | congenital muscular dystrophy | 1.2195 | 7 | no |
DOID:0080000 | muscular disease | 1.2195 | 3 | no |
DOID:423 | myopathy | 1.2195 | 5 | no |
DOID:66 | muscle tissue disease | 1.2195 | 4 | no |
DOID:9884 | muscular dystrophy | 1.2195 | 6 | no |
DOID:12930 | dilated cardiomyopathy | 1.2195 | 6 | no |
DOID:65 | connective tissue disease | 1.2195 | 3 | no |
Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
---|---|---|---|---|
LMNA_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
ANXA6_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
RBP1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
NFKB1_HUMAN | [view interactions] | Low throughput | no | yes |
NCF1_HUMAN | [view interactions] | Low throughput | no | no |
JAK2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
KPCA_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
CBL_HUMAN | [view interactions] | Low throughput | no | yes |
EGFR_HUMAN | [view interactions] | Low throughput | no | no |
CD151_HUMAN | [view interactions] | Low throughput | no | no |
PPARG_HUMAN | [view interactions] | Low throughput | no | yes |
SIN1_HUMAN | [view interactions] | Low throughput | no | yes |
FSCN1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
EAA3_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
PLD1_HUMAN | [view interactions] | Low throughput | no | no |
PLD2_HUMAN | [view interactions] | Low throughput | no | yes |
CXA1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
1433G_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
V1AR_HUMAN | [view interactions] | Low throughput | no | no |
V1BR_HUMAN | [view interactions] | Low throughput | no | no |
OGG1_HUMAN | [view interactions] | Low throughput | no | yes |
1433Z_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
RACK1_HUMAN | [view interactions] | Low throughput | no | yes |
ITB1_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
EZRI_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
CD53_HUMAN | [view interactions] | Low throughput | no | yes |
CD9_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
IKKB_HUMAN | [view interactions] | Low throughput | no | yes |
IKKA_HUMAN | [view interactions] | Low throughput | no | yes |
AKAP5_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
DDX58_HUMAN | [view interactions] | Low throughput | no | yes |
ITB3_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
ELAV1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
LNX1_HUMAN | [view interactions] | Low throughput | no | yes |
LNX2_HUMAN | [view interactions] | Low throughput | no | yes |
IBTK_HUMAN | [view interactions] | Low throughput | no | yes |
AKP13_HUMAN | [view interactions] | Low throughput | no | yes |
LYAM1_HUMAN | [view interactions] | Low throughput | no | no |
CISH_HUMAN | [view interactions] | Low throughput | no | yes |
FBXW7_HUMAN | [view interactions] | Low throughput | no | yes |
PLCG2_HUMAN | [view interactions] | Low throughput | no | yes |
HOIL1_HUMAN | [view interactions] | Low throughput | no | no |
PA24A_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
EP300_HUMAN | [view interactions] | Low throughput | no | yes |
PAR6A_HUMAN | [view interactions] | Low throughput | no | yes |
LRP1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
CADH5_HUMAN | [view interactions] | Low throughput | no | yes |
ENPL_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
TRIB3_HUMAN | [view interactions] | Low throughput | no | yes |
NUMB_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
ATM_HUMAN | [view interactions] | Low throughput | no | yes |
GBRB3_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
AFAP1_HUMAN | [view interactions] | Low throughput | no | yes |
LMNB1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
PP14A_HUMAN | [view interactions] | Low throughput | no | yes |
NHRF1_HUMAN | [view interactions] | Low throughput | no | no |
NHRF2_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
FCG2B_HUMAN | [view interactions] | Low throughput | no | no |
AT1A1_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
HABP4_HUMAN | [view interactions] | Low throughput | no | yes |
HAND1_HUMAN | [view interactions] | Low throughput | no | yes |
HAND2_HUMAN | [view interactions] | Low throughput | no | yes |
KLF5_HUMAN | [view interactions] | Low throughput | no | yes |
MGMT_HUMAN | [view interactions] | Low throughput | no | no |
GSK3B_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
RGS2_HUMAN | [view interactions] | Low throughput | no | no |
TIAM1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
HMGA1_HUMAN | [view interactions] | Low throughput | no | yes |
HMGA2_HUMAN | [view interactions] | Low throughput | no | yes |
STP1_HUMAN | [view interactions] | Low throughput | no | no |
SDC4_HUMAN | [view interactions] | Low throughput | no | yes |
STP2_HUMAN | [view interactions] | Low throughput | no | no |
LDB3_HUMAN | [view interactions] | Low throughput | no | no |
H31_HUMAN | [view interactions] | Low throughput | no | yes |
GRM7_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
MTOR_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
PICK1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
TRPV6_HUMAN | [view interactions] | Low throughput | no | no |
RICTR_HUMAN | [view interactions] | Low throughput | no | yes |
H11_HUMAN | [view interactions] | Low throughput | no | no |
UBC_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
H15_HUMAN | [view interactions] | Low throughput | no | no |
HDAC6_HUMAN | [view interactions] | Low throughput | no | yes |
LIMK1_HUMAN | [view interactions] | Low throughput | no | yes |
NR1H2_HUMAN | [view interactions] | Low throughput | no | yes |
H31T_HUMAN | [view interactions] | Low throughput | no | yes |
GLI3_HUMAN | [view interactions] | Low throughput | no | yes |
SCRIB_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
TOP2A_HUMAN | [view interactions] | Low throughput | no | no |
F261_HUMAN | [view interactions] | Low throughput | no | no |
TAU_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
VTNC_HUMAN | [view interactions] | Low throughput | no | no |
MARCS_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
SDC2_HUMAN | [view interactions] | Low throughput | no | yes |
ITB2_HUMAN | [view interactions] | Low throughput | no | no |
GSK3A_HUMAN | [view interactions] | Low throughput | no | yes |
NMDZ1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
NMDE2_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
CASR_HUMAN | [view interactions] | Low throughput | no | no |
NOXA1_HUMAN | [view interactions] | Low throughput | no | yes |
RAD_HUMAN | [view interactions] | Low throughput | no | yes |
KPCE_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
IKBA_HUMAN | [view interactions] | Low throughput | no | yes |
AKA12_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
HMGN1_HUMAN | [view interactions] | Low throughput | no | yes |
HMGN2_HUMAN | [view interactions] | Low throughput | no | no |
PI2R_HUMAN | [view interactions] | Low throughput | no | no |
TA2R_HUMAN | [view interactions] | Low throughput | no | no |
CP3A4_HUMAN | [view interactions] | Low throughput | no | no |
GRM5_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
C1QBP_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
RNF31_HUMAN | [view interactions] | Low throughput | no | yes |
GRB2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
STXB1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
TRI41_HUMAN | [view interactions] | Low throughput | no | yes |
SPAG1_HUMAN | [view interactions] | Low throughput | no | no |
PDLI7_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
BTG2_HUMAN | [view interactions] | Low throughput | no | yes |
NF2L2_HUMAN | [view interactions] | Low throughput | no | yes |
CYBP_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
MERL_HUMAN | [view interactions] | Low throughput | no | yes |
RAC1_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
HAIR_HUMAN | [view interactions] | Low throughput | no | no |
INADL_HUMAN | [view interactions] | Low throughput | no | no |
PPM1A_HUMAN | [view interactions] | Low throughput | no | yes |
GIPC1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
KC1D_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
DLG3_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
DLG4_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
EGLN2_HUMAN | [view interactions] | Low throughput | no | no |
BRAF_HUMAN | [view interactions] | Low throughput | no | yes |
FCG3A_HUMAN | [view interactions] | Low throughput | no | no |
KS6A2_HUMAN | [view interactions] | Low throughput | no | yes |
PHB2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
TYK2_HUMAN | [view interactions] | Low throughput | no | no |
ADDA_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
IF2A_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
NMDE3_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
JAK1_HUMAN | [view interactions] | Low throughput | no | yes |
GRIA1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
CLOCK_HUMAN | [view interactions] | Low throughput | no | yes |
TEP1_HUMAN | [view interactions] | Low throughput | no | no |
CTNB1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
TERT_HUMAN | [view interactions] | Low throughput | no | no |
HOME1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
SHAN3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
ANS1B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
ACINU_HUMAN | [view interactions] | High throughput | no | yes |
TRIO_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
DESP_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
F262_HUMAN | [view interactions] | High throughput | no | no |
AT2B1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
GFAP_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
STXB3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
GPM6A_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
CDN2A_HUMAN | [view interactions] | High throughput | no | yes |
MK01_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
PSB4_HUMAN | [view interactions] | High throughput | no | yes |
MK03_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
SAC1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
CYH2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
NEUG_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
ID2_HUMAN | [view interactions] | High throughput | no | no |
TIAM2_HUMAN | [view interactions] | High throughput | no | yes |
HNRPF_HUMAN | [view interactions] | High throughput | no | yes |
DYLT1_HUMAN | [view interactions] | High throughput | no | no |
DRD1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
CLPP_HUMAN | [view interactions] | High throughput | no | yes |
CATO_HUMAN | [view interactions] | High throughput | no | yes |
PER2_HUMAN | [view interactions] | High throughput | no | yes |
CBPN_HUMAN | [view interactions] | High throughput | no | no |
BAGE1_HUMAN | [view interactions] | High throughput | no | no |
POLI_HUMAN | [view interactions] | High throughput | no | yes |
DNPH1_HUMAN | [view interactions] | High throughput | no | yes |
HXB13_HUMAN | [view interactions] | High throughput | no | no |
PIAS3_HUMAN | [view interactions] | High throughput | no | yes |
RHBT1_HUMAN | [view interactions] | High throughput | no | yes |
ACAP1_HUMAN | [view interactions] | High throughput | no | yes |
SNG3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
VNN2_HUMAN | [view interactions] | High throughput | no | no |
H4_HUMAN | [view interactions] | High throughput | no | yes |
ZSC9_HUMAN | [view interactions] | High throughput | no | yes |
ITF2_HUMAN | [view interactions] | High throughput | no | yes |
SOX10_HUMAN | [view interactions] | High throughput | no | yes |
C560_HUMAN | [view interactions] | High throughput | no | no |
RL35A_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
PROS_HUMAN | [view interactions] | High throughput | no | no |
MK11_HUMAN | [view interactions] | High throughput | no | yes |
NDUV1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
M3K9_HUMAN | [view interactions] | High throughput | no | yes |
LUM_HUMAN | [view interactions] | High throughput | no | no |
EIF3E_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
IL3RA_HUMAN | [view interactions] | High throughput | no | yes |
IBP3_HUMAN | [view interactions] | High throughput | no | no |
CCD47_HUMAN | [view interactions] | High throughput | no | yes |
PELO_HUMAN | [view interactions] | High throughput | no | yes |
LIPT_HUMAN | [view interactions] | High throughput | no | no |
SNX10_HUMAN | [view interactions] | High throughput | no | yes |
MAGH1_HUMAN | [view interactions] | High throughput | no | yes |
T176B_HUMAN | [view interactions] | High throughput | no | yes |
DEXI_HUMAN | [view interactions] | High throughput | no | yes |
GP160_HUMAN | [view interactions] | High throughput | no | yes |
MET7A_HUMAN | [view interactions] | High throughput | no | no |
FSCN2_HUMAN | [view interactions] | High throughput | no | no |
SEPT6_HUMAN | [view interactions] | High throughput | no | yes |
UBP38_HUMAN | [view interactions] | High throughput | no | no |
KRA31_HUMAN | [view interactions] | High throughput | no | no |
ZFY21_HUMAN | [view interactions] | High throughput | no | yes |
SYUA_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
HS90B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
TNR6_HUMAN | [view interactions] | High throughput | no | no |
IMP2L_HUMAN | [view interactions] | High throughput | no | yes |
BAP1_HUMAN | [view interactions] | High throughput | no | yes |
HS90A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
NPM_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
CALM2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
CALM3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
CALM1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
MOV10_HUMAN | [view interactions] | High throughput | no | no |
NXF1_HUMAN | [view interactions] | High throughput | no | yes |
CCDC8_HUMAN | [view interactions] | High throughput | no | yes |
M2OM_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
T185A_HUMAN | [view interactions] | High throughput | no | no |
JSPR1_HUMAN | [view interactions] | High throughput | no | no |
CCNL2_HUMAN | [view interactions] | High throughput | no | yes |
VPS4B_HUMAN | [view interactions] | High throughput | no | yes |
QCR7_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
WWC2_HUMAN | [view interactions] | High throughput | no | yes |
WWC3_HUMAN | [view interactions] | High throughput | no | yes |
KIBRA_HUMAN | [view interactions] | High throughput | no | yes |
NTRK1_HUMAN | [view interactions] | High throughput | no | yes |
PI51A_HUMAN | [view interactions] | High throughput | no | yes |
CP2S1_HUMAN | [view interactions] | High throughput | no | no |
AGAP2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
FACD2_HUMAN | [view interactions] | High throughput | no | no |
TES_HUMAN | [view interactions] | High throughput | no | yes |
MYC_HUMAN | [view interactions] | High throughput | no | yes |
VIR_HUMAN | [view interactions] | High throughput | no | yes |
BIG3_HUMAN | [view interactions] | High throughput | no | yes |
RGS14_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
PKHA4_HUMAN | [view interactions] | High throughput | no | yes |
BAD_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
MK07_HUMAN | [view interactions] | High throughput | no | yes |
KAP0_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
HS71B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
HS71A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
KPCZ_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
MKRN2_HUMAN | [view interactions] | High throughput | no | yes |
CERS2_HUMAN | [view interactions] | High throughput | no | no |
ARMS2_HUMAN | [view interactions] | High throughput | no | no |
PIPNB_HUMAN | [view interactions] | High throughput | no | no |
OPALI_HUMAN | [view interactions] | High throughput | no | yes |
TFAP4_HUMAN | [view interactions] | High throughput | no | yes |
FRIH_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
F133A_HUMAN | [view interactions] | High throughput | no | no |
INSRR_HUMAN | [view interactions] | High throughput | no | no |
PAIRB_HUMAN | [view interactions] | High throughput | no | yes |
FHR3_HUMAN | [view interactions] | High throughput | no | no |
TFDP2_HUMAN | [view interactions] | High throughput | no | yes |
TACAN_HUMAN | [view interactions] | High throughput | no | no |
TRNT1_HUMAN | [view interactions] | High throughput | no | yes |
DPPA3_HUMAN | [view interactions] | High throughput | no | no |
PAHO_HUMAN | [view interactions] | High throughput | no | no |
TMM53_HUMAN | [view interactions] | High throughput | no | yes |
T2EB_HUMAN | [view interactions] | High throughput | no | yes |
P20L1_HUMAN | [view interactions] | High throughput | no | yes |
RDH11_HUMAN | [view interactions] | High throughput | no | no |
ISOC1_HUMAN | [view interactions] | High throughput | no | no |
ANLN_HUMAN | [view interactions] | High throughput | no | yes |
UBA5_HUMAN | [view interactions] | High throughput | no | yes |
CSK22_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
GPI8_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
CCR3_HUMAN | [view interactions] | High throughput | no | yes |
T2R20_HUMAN | [view interactions] | High throughput | no | no |
BPHL_HUMAN | [view interactions] | High throughput | no | no |
TBD_HUMAN | [view interactions] | High throughput | no | yes |
UBL4A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
CLD10_HUMAN | [view interactions] | High throughput | no | no |
PEX3_HUMAN | [view interactions] | High throughput | no | yes |
IL23R_HUMAN | [view interactions] | High throughput | no | yes |
ZDH23_HUMAN | [view interactions] | High throughput | no | no |
MUS81_HUMAN | [view interactions] | High throughput | no | no |
PDE7A_HUMAN | [view interactions] | High throughput | no | yes |
SCP2_HUMAN | [view interactions] | High throughput | no | no |
FACC1_HUMAN | [view interactions] | High throughput | no | no |
SEPT9_HUMAN | [view interactions] | High throughput | no | no |
AMFR_HUMAN | [view interactions] | High throughput | no | yes |
PK3CA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
RON_HUMAN | [view interactions] | High throughput | no | yes |
FN3K_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
H12_HUMAN | [view interactions] | High throughput | no | yes |
KIF11_HUMAN | [view interactions] | High throughput | no | yes |
H13_HUMAN | [view interactions] | High throughput | no | no |
SPF27_HUMAN | [view interactions] | High throughput | no | yes |
H14_HUMAN | [view interactions] | High throughput | no | yes |
CTBL1_HUMAN | [view interactions] | High throughput | no | yes |
H1T_HUMAN | [view interactions] | High throughput | no | no |
KIF2A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
4EBP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
MBP_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
S2541_HUMAN | [view interactions] | High throughput | no | no |
STAR7_HUMAN | [view interactions] | High throughput | no | yes |
FGD4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
SHCBP_HUMAN | [view interactions] | High throughput | no | no |
GSH0_HUMAN | [view interactions] | High throughput | no | yes |
KPCL_HUMAN | [view interactions] | High throughput | no | yes |
KPCG_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
FBX21_HUMAN | [view interactions] | High throughput | no | yes |
DUS11_HUMAN | [view interactions] | High throughput | no | no |
TA2R7_HUMAN | [view interactions] | High throughput | no | no |
MYO1C_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
KPRB_HUMAN | [view interactions] | High throughput | no | yes |
PRPS2_HUMAN | [view interactions] | High throughput | no | no |
SYVC_HUMAN | [view interactions] | High throughput | no | yes |
ACTB_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
PRPS1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
ACTG_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
KPRA_HUMAN | [view interactions] | High throughput | no | no |
CDC37_HUMAN | [view interactions] | High throughput | no | yes |
FBX25_HUMAN | [view interactions] | High throughput | no | no |
DREB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
NS1BP_HUMAN | [view interactions] | High throughput | no | yes |
HSPB1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
HYOU1_HUMAN | [view interactions] | High throughput | no | yes |
MB212_HUMAN | [view interactions] | High throughput | no | no |
KPCB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
GLYG_HUMAN | [view interactions] | High throughput | no | yes |
KPCD_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
SMUF1_HUMAN | [view interactions] | High throughput | no | yes |
FBX7_HUMAN | [view interactions] | High throughput | no | yes |
SMO_HUMAN | [view interactions] | Computational | no | yes |
GRIP1_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
GRIA2_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
GRIA4_HUMAN | [view entry] [view interactions] | Computational | yes | no |
LAMC2_HUMAN | [view interactions] | Computational | no | no |
CABIN_HUMAN | [view interactions] | Computational | no | yes |
SL9A1_HUMAN | [view interactions] | Computational | no | no |
ITPR2_HUMAN | [view interactions] | Computational | no | yes |
DECR_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
RAB4A_HUMAN | [view entry] [view interactions] | Computational | yes | no |
PIN1_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
GNB5_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
PLCD4_HUMAN | [view interactions] | Computational | no | no |
PKP2_HUMAN | [view interactions] | Computational | no | yes |
GNAS1_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
SOS2_HUMAN | [view interactions] | Computational | no | yes |
CAV1_HUMAN | [view interactions] | Computational | no | no |
ITPR3_HUMAN | [view interactions] | Computational | no | yes |
PLCG1_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
LEMD2_HUMAN | [view interactions] | Computational | no | yes |
LAMB1_HUMAN | [view interactions] | Computational | no | yes |
1433E_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
CRK_HUMAN | [view entry] [view interactions] | Computational | yes | no |
RHOA_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
PDK2_HUMAN | [view interactions] | Computational | no | yes |
PAX8_HUMAN | [view interactions] | Computational | no | yes |
KEAP1_HUMAN | [view interactions] | Computational | no | yes |
1433B_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
ADA12_HUMAN | [view interactions] | Computational | no | no |
SRC_HUMAN | [view entry] [view interactions] | Computational | yes | no |
EMD_HUMAN | [view interactions] | Computational | no | yes |
PLCB1_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
MMP3_HUMAN | [view interactions] | Computational | no | no |
GRIA3_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
AP2A2_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
DVL2_HUMAN | [view interactions] | Computational | no | yes |
KS6B1_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
AP2B1_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
PDPK1_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
KIT_HUMAN | [view interactions] | Computational | no | no |
GFRA1_HUMAN | [view interactions] | Computational | no | no |
VAS1_HUMAN | [view interactions] | Computational | no | yes |
NCF2_HUMAN | [view interactions] | Computational | no | no |
LAMA1_HUMAN | [view interactions] | Computational | no | no |
SPHK2_HUMAN | [view interactions] | Computational | no | no |
SPHK1_HUMAN | [view interactions] | Computational | no | yes |
KPCD1_HUMAN | [view interactions] | Computational | no | yes |
PLCD1_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
SC6A3_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
RGS9_HUMAN | [view entry] [view interactions] | Computational | yes | no |
TTF1_HUMAN | [view interactions] | Computational | no | yes |
PLCD3_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
ADCY8_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
RXRB_HUMAN | [view interactions] | Computational | no | yes |
LAP2A_HUMAN | [view interactions] | Computational | no | yes |
RXRA_HUMAN | [view interactions] | Computational | no | yes |
STA5A_HUMAN | [view interactions] | Computational | no | no |
PPR1A_HUMAN | [view interactions] | Computational | no | yes |
RASK_HUMAN | [view entry] [view interactions] | Computational | yes | no |
LST8_HUMAN | [view interactions] | Computational | no | yes |
PLCZ1_HUMAN | [view interactions] | Computational | no | no |
R9BP_HUMAN | [view interactions] | Computational | no | no |
CASP3_HUMAN | [view interactions] | Computational | no | yes |
EGLN1_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
PLPL9_HUMAN | [view interactions] | Computational | no | yes |
CAC1C_HUMAN | [view entry] [view interactions] | Computational | yes | no |
RASH_HUMAN | [view entry] [view interactions] | Computational | yes | no |
FZD4_HUMAN | [view interactions] | Computational | no | yes |
NRG2_HUMAN | [view interactions] | Computational | no | yes |
PRR5_HUMAN | [view interactions] | Computational | no | yes |
MP2K7_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
TRPC3_HUMAN | [view interactions] | Computational | no | no |
TF65_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
GNAQ_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
EGLN3_HUMAN | [view interactions] | Computational | no | no |
WNT5A_HUMAN | [view entry] [view interactions] | Computational | yes | no |
ILK_HUMAN | [view interactions] | Computational | no | no |
FLNA_HUMAN | [view entry] [view interactions] | Computational | yes | no |
MAN1_HUMAN | [view interactions] | Computational | no | yes |
RAF1_HUMAN | [view entry] [view interactions] | Computational | yes | no |
GDNF_HUMAN | [view interactions] | Computational | no | yes |
GBG1_HUMAN | [view interactions] | Computational | no | no |
DAG1_HUMAN | [view entry] [view interactions] | Computational | yes | no |
NCF4_HUMAN | [view interactions] | Computational | no | no |
NRG4_HUMAN | [view interactions] | Computational | no | no |
MP2K4_HUMAN | [view interactions] | Computational | no | yes |
FAK1_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
PPARA_HUMAN | [view interactions] | Computational | no | yes |
EGF_HUMAN | [view interactions] | Computational | no | no |
ERBB4_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
NOS1_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
NRG3_HUMAN | [view interactions] | Computational | no | no |
STX4_HUMAN | [view entry] [view interactions] | Computational | yes | no |
GBB1_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
ATF2_HUMAN | [view interactions] | Computational | no | yes |
GDIR1_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
TTF2_HUMAN | [view interactions] | Computational | no | yes |
STA5B_HUMAN | [view interactions] | Computational | no | yes |
TRPV4_HUMAN | [view interactions] | Computational | no | yes |
KPCD2_HUMAN | [view interactions] | Computational | no | yes |
CAC1A_HUMAN | [view interactions] | Computational | no | no |
KPCD3_HUMAN | [view interactions] | Computational | no | yes |
ITA6_HUMAN | [view interactions] | Computational | no | yes |
DKC1_HUMAN | [view interactions] | Computational | no | yes |
AP2M1_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
1433T_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
FAK2_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
PLCE1_HUMAN | [view interactions] | Computational | no | yes |
CD38_HUMAN | [view interactions] | Computational | no | no |
AP2A1_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
RXRG_HUMAN | [view interactions] | Computational | no | no |
ITB4_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
SHC1_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
RET_HUMAN | [view interactions] | Computational | no | yes |
AP2S1_HUMAN | [view entry] [view interactions] | Computational | yes | no |
NEMO_HUMAN | [view interactions] | Computational | no | yes |
RARA_HUMAN | [view interactions] | Computational | no | no |
ADA17_HUMAN | [view interactions] | Computational | no | yes |
LYN_HUMAN | [view entry] [view interactions] | Computational | yes | no |
EF2K_HUMAN | [view entry] [view interactions] | Computational | yes | no |
FOS_HUMAN | [view interactions] | Computational | no | yes |
ARBK1_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
RASN_HUMAN | [view entry] [view interactions] | Computational | yes | no |
1433S_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
1433F_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
BCAR1_HUMAN | [view interactions] | Computational | no | yes |