GSK3B_HUMAN
Constitutively active protein kinase that acts as a negative regulator in the hormonal control of glucose homeostasis, Wnt signaling and regulation of transcription factors and microtubules, by phosphorylating and inactivating glycogen synthase (GYS1 or GYS2), EIF2B, CTNNB1/beta-catenin, APC, AXIN1, DPYSL2/CRMP2, JUN, NFATC1/NFATC, MAPT/TAU and MACF1. Requires primed phosphorylation of the majority of its substrates. In skeletal muscle, contributes to insulin regulation of glycogen synthesis by phosphorylating and inhibiting GYS1 activity and hence glycogen synthesis. May also mediate the development of insulin resistance by regulating activation of transcription factors. Regulates protein synthesis by controlling the activity of initiation factor 2B (EIF2BE/EIF2B5) in the same manner as glycogen synthase. In Wnt signaling, GSK3B forms a multimeric complex with APC, AXIN1 and CTNNB1/beta-catenin and phosphorylates the N-terminus of CTNNB1 leading to its degradation mediated by ubiquitin/proteasomes. Phosphorylates JUN at sites proximal to its DNA-binding domain, thereby reducing its affinity for DNA. Phosphorylates NFATC1/NFATC on conserved serine residues promoting NFATC1/NFATC nuclear export, shutting off NFATC1/NFATC gene regulation, and thereby opposing the action of calcineurin. Phosphorylates MAPT/TAU on Thr-548, decreasing significantly MAPT/TAU ability to bind and stabilize microtubules. MAPT/TAU is the principal component of neurofibrillary tangles in Alzheimer disease. Plays an important role in ERBB2-dependent stabilization of microtubules at the cell cortex. Phosphorylates MACF1, inhibiting its binding to microtubules which is critical for its role in bulge stem cell migration and skin wound repair. Probably regulates NF-kappa-B (NFKB1) at the transcriptional level and is required for the NF-kappa-B-mediated anti-apoptotic response to TNF-alpha (TNF/TNFA). Negatively regulates replication in pancreatic beta-cells, resulting in apoptosis, loss of beta-cells and diabetes. Through phosphorylation of the anti-apoptotic protein MCL1, may control cell apoptosis in response to growth factors deprivation. Phosphorylates MUC1 in breast cancer cells, decreasing the interaction of MUC1 with CTNNB1/beta-catenin. Is necessary for the establishment of neuronal polarity and axon outgrowth. Phosphorylates MARK2, leading to inhibit its activity. Phosphorylates SIK1 at Thr-182, leading to sustain its activity. Phosphorylates ZC3HAV1 which enhances its antiviral activity. Phosphorylates SNAI1, leading to its BTRC-triggered ubiquitination and proteasomal degradation. Phosphorylates SFPQ at Thr-687 upon T-cell activation. Phosphorylates NR1D1 st Ser-55 and Ser-59 and stabilizes it by protecting it from proteasomal degradation. Regulates the circadian clock via phosphorylation of the major clock components including ARNTL/BMAL1, CLOCK and PER2 (PubMed, PubMed). Phosphorylates CLOCK AT Ser-427 and targets it for proteasomal degradation (PubMed). Phosphorylates ARNTL/BMAL1 at Ser-17 and Ser-21 and primes it for ubiquitination and proteasomal degradation (PubMed). Phosphorylates OGT at Ser-3 or Ser-4 which positively regulates its activity. Phosphorylates MYCN in neuroblastoma cells which may promote its degradation (PubMed). Regulates the circadian rhythmicity of hippocampal long-term potentiation and ARNTL/BMLA1 and PER2 expression . Acts as a regulator of autophagy by mediating phosphorylation of KAT5/TIP60 under starvation conditions, leading to activate KAT5/TIP60 acetyltransferase activity and promote acetylation of key autophagy regulators, such as ULK1 and RUBCNL/Pacer (PubMed). Negatively regulates extrinsic apoptotic signaling pathway via death domain receptors. Promotes the formation of an anti-apoptotic complex, made of DDX3X, BRIC2 and GSK3B, at death receptors, including TNFRSF10B. The anti-apoptotic function is most effective with weak apoptotic signals and can be overcome by stronger stimulation (PubMed). [View more on UniProt]
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No data found.
No annotated instance was found. To search for linear motifs, use the ELM prediction server.
Molecular function
Term | Name | % | Distance from the top of the tree | Annotated in GSK3B_HUMAN |
---|---|---|---|---|
GO:0017076 | purine nucleotide binding | 32.4627 | 4 | yes |
GO:0032555 | purine ribonucleotide binding | 32.0896 | 4 | yes |
GO:0030554 | adenyl nucleotide binding | 30.2239 | 5 | yes |
GO:0032559 | adenyl ribonucleotide binding | 29.8507 | 5 | yes |
GO:0035639 | purine ribonucleoside triphosphate binding | 29.8507 | 4 | yes |
GO:0003723 | RNA binding | 28.7313 | 4 | no |
GO:0005524 | ATP binding | 27.6119 | 5 | yes |
GO:0046872 | metal ion binding | 23.1343 | 4 | no |
GO:0019900 | kinase binding | 20.5224 | 4 | yes |
GO:0019901 | protein kinase binding | 19.7761 | 5 | yes |
GO:0016301 | kinase activity | 14.1791 | 4 | yes |
GO:0016773 | phosphotransferase activity, alcohol group as acceptor | 13.8060 | 4 | yes |
GO:0031625 | ubiquitin protein ligase binding | 12.3134 | 5 | yes |
GO:0044389 | ubiquitin-like protein ligase binding | 12.3134 | 4 | yes |
GO:0004712 | protein serine/threonine/tyrosine kinase activity | 11.5672 | 4 | yes |
GO:0004674 | protein serine/threonine kinase activity | 10.8209 | 4 | yes |
GO:0106310 | protein serine kinase activity | 10.0746 | 4 | yes |
GO:0140297 | DNA-binding transcription factor binding | 5.5970 | 4 | yes |
GO:0048156 | tau protein binding | 4.8507 | 4 | yes |
GO:0061629 | RNA polymerase II-specific DNA-binding transcription factor binding | 4.4776 | 5 | yes |
GO:0002020 | protease binding | 3.7313 | 4 | yes |
GO:0050321 | tau-protein kinase activity | 2.2388 | 4 | yes |
GO:0034236 | protein kinase A catalytic subunit binding | 1.8657 | 4 | yes |
GO:0034452 | dynactin binding | 1.1194 | 4 | yes |
GO:0051059 | NF-kappaB binding | 1.1194 | 6 | yes |
Biological process
Term | Name | % | Distance from top the of the tree | Annotated in GSK3B_HUMAN |
---|---|---|---|---|
GO:0048522 | positive regulation of cellular process | 58.2090 | 4 | yes |
GO:0060255 | regulation of macromolecule metabolic process | 57.8358 | 4 | yes |
GO:0080090 | regulation of primary metabolic process | 55.5970 | 4 | yes |
GO:0051171 | regulation of nitrogen compound metabolic process | 54.4776 | 4 | yes |
GO:0048523 | negative regulation of cellular process | 53.7313 | 4 | yes |
GO:0031323 | regulation of cellular metabolic process | 51.8657 | 4 | yes |
GO:0051128 | regulation of cellular component organization | 44.0299 | 4 | yes |
GO:0010646 | regulation of cell communication | 42.5373 | 4 | yes |
GO:0010468 | regulation of gene expression | 42.1642 | 5 | yes |
GO:0009893 | positive regulation of metabolic process | 41.4179 | 4 | yes |
GO:0051246 | regulation of protein metabolic process | 41.0448 | 5 | yes |
GO:0010604 | positive regulation of macromolecule metabolic process | 39.9254 | 5 | yes |
GO:0009889 | regulation of biosynthetic process | 37.3134 | 4 | yes |
GO:0009966 | regulation of signal transduction | 37.3134 | 4 | yes |
GO:0031326 | regulation of cellular biosynthetic process | 36.5672 | 5 | yes |
GO:0051173 | positive regulation of nitrogen compound metabolic process | 36.5672 | 5 | yes |
GO:0010556 | regulation of macromolecule biosynthetic process | 35.0746 | 5 | yes |
GO:0022607 | cellular component assembly | 34.7015 | 4 | no |
GO:0031325 | positive regulation of cellular metabolic process | 34.7015 | 5 | yes |
GO:0006996 | organelle organization | 33.9552 | 4 | yes |
GO:0009892 | negative regulation of metabolic process | 31.3433 | 4 | yes |
GO:0008104 | protein localization | 30.2239 | 4 | no |
GO:0010605 | negative regulation of macromolecule metabolic process | 29.8507 | 5 | yes |
GO:0019219 | regulation of nucleobase-containing compound metabolic process | 29.8507 | 5 | no |
GO:0010941 | regulation of cell death | 29.4776 | 4 | yes |
GO:0051247 | positive regulation of protein metabolic process | 28.7313 | 6 | yes |
GO:0048584 | positive regulation of response to stimulus | 28.3582 | 4 | no |
GO:0051172 | negative regulation of nitrogen compound metabolic process | 27.9851 | 5 | yes |
GO:0031399 | regulation of protein modification process | 27.2388 | 6 | yes |
GO:0031324 | negative regulation of cellular metabolic process | 26.4925 | 5 | yes |
GO:0051049 | regulation of transport | 26.4925 | 4 | yes |
GO:0051130 | positive regulation of cellular component organization | 26.4925 | 5 | yes |
GO:0019220 | regulation of phosphate metabolic process | 26.1194 | 6 | yes |
GO:0051174 | regulation of phosphorus metabolic process | 26.1194 | 5 | yes |
GO:0071310 | cellular response to organic substance | 25.7463 | 4 | yes |
GO:0043067 | regulation of programmed cell death | 25.7463 | 5 | yes |
GO:0006796 | phosphate-containing compound metabolic process | 25.3731 | 4 | yes |
GO:0023056 | positive regulation of signaling | 25.3731 | 4 | no |
GO:0036211 | protein modification process | 25.3731 | 4 | yes |
GO:0043412 | macromolecule modification | 25.3731 | 4 | yes |
GO:0051252 | regulation of RNA metabolic process | 25.0000 | 5 | no |
GO:0010647 | positive regulation of cell communication | 25.0000 | 5 | no |
GO:0042981 | regulation of apoptotic process | 25.0000 | 6 | yes |
GO:0009894 | regulation of catabolic process | 24.6269 | 4 | yes |
GO:1902531 | regulation of intracellular signal transduction | 24.2537 | 5 | yes |
GO:0033043 | regulation of organelle organization | 24.2537 | 5 | yes |
GO:0071702 | organic substance transport | 23.1343 | 4 | no |
GO:0045595 | regulation of cell differentiation | 23.1343 | 4 | yes |
GO:0009891 | positive regulation of biosynthetic process | 22.7612 | 5 | no |
GO:0042325 | regulation of phosphorylation | 22.7612 | 7 | no |
GO:0009967 | positive regulation of signal transduction | 22.7612 | 5 | no |
GO:0043933 | protein-containing complex organization | 22.7612 | 4 | yes |
GO:0060341 | regulation of cellular localization | 22.7612 | 4 | yes |
GO:0006355 | regulation of DNA-templated transcription | 22.3881 | 6 | no |
GO:0071705 | nitrogen compound transport | 22.3881 | 4 | no |
GO:1903506 | regulation of nucleic acid-templated transcription | 22.3881 | 7 | no |
GO:2001141 | regulation of RNA biosynthetic process | 22.3881 | 6 | no |
GO:0031328 | positive regulation of cellular biosynthetic process | 22.0149 | 6 | no |
GO:0048585 | negative regulation of response to stimulus | 22.0149 | 4 | yes |
GO:0010648 | negative regulation of cell communication | 21.2687 | 5 | yes |
GO:0023057 | negative regulation of signaling | 21.2687 | 4 | yes |
GO:0044087 | regulation of cellular component biogenesis | 21.2687 | 4 | yes |
GO:0051240 | positive regulation of multicellular organismal process | 20.8955 | 4 | no |
GO:0001932 | regulation of protein phosphorylation | 20.8955 | 7 | no |
GO:0030030 | cell projection organization | 20.8955 | 4 | yes |
GO:0060548 | negative regulation of cell death | 20.8955 | 5 | yes |
GO:0032880 | regulation of protein localization | 20.5224 | 5 | yes |
GO:0010557 | positive regulation of macromolecule biosynthetic process | 20.1493 | 6 | no |
GO:0007010 | cytoskeleton organization | 20.1493 | 5 | no |
GO:0051248 | negative regulation of protein metabolic process | 20.1493 | 6 | yes |
GO:0051094 | positive regulation of developmental process | 19.7761 | 4 | yes |
GO:0080134 | regulation of response to stress | 18.6567 | 4 | yes |
GO:0009968 | negative regulation of signal transduction | 18.6567 | 5 | yes |
GO:0010628 | positive regulation of gene expression | 18.6567 | 6 | yes |
GO:0031329 | regulation of cellular catabolic process | 18.6567 | 5 | yes |
GO:0051129 | negative regulation of cellular component organization | 18.6567 | 5 | yes |
GO:0051338 | regulation of transferase activity | 18.6567 | 4 | yes |
GO:0120035 | regulation of plasma membrane bounded cell projection organization | 18.2836 | 6 | yes |
GO:0031344 | regulation of cell projection organization | 18.2836 | 5 | yes |
GO:0022603 | regulation of anatomical structure morphogenesis | 17.9104 | 4 | yes |
GO:0043085 | positive regulation of catalytic activity | 17.9104 | 4 | yes |
GO:0010243 | response to organonitrogen compound | 17.5373 | 4 | yes |
GO:0043069 | negative regulation of programmed cell death | 17.5373 | 6 | yes |
GO:0051050 | positive regulation of transport | 17.5373 | 4 | yes |
GO:0120036 | plasma membrane bounded cell projection organization | 17.1642 | 5 | yes |
GO:0043066 | negative regulation of apoptotic process | 17.1642 | 7 | yes |
GO:1901701 | cellular response to oxygen-containing compound | 16.4179 | 4 | yes |
GO:0030162 | regulation of proteolysis | 15.6716 | 6 | yes |
GO:0051336 | regulation of hydrolase activity | 15.6716 | 4 | yes |
GO:0016310 | phosphorylation | 15.2985 | 5 | yes |
GO:1903829 | positive regulation of protein localization | 14.5522 | 5 | yes |
GO:0010975 | regulation of neuron projection development | 14.5522 | 7 | yes |
GO:0042176 | regulation of protein catabolic process | 14.5522 | 5 | yes |
GO:0099177 | regulation of trans-synaptic signaling | 13.8060 | 4 | yes |
GO:0006468 | protein phosphorylation | 13.8060 | 5 | yes |
GO:0010638 | positive regulation of organelle organization | 13.8060 | 6 | yes |
GO:0031400 | negative regulation of protein modification process | 13.8060 | 7 | yes |
GO:0045597 | positive regulation of cell differentiation | 13.8060 | 5 | yes |
GO:0050804 | modulation of chemical synaptic transmission | 13.8060 | 5 | yes |
GO:0009890 | negative regulation of biosynthetic process | 13.4328 | 5 | yes |
GO:0018193 | peptidyl-amino acid modification | 13.4328 | 5 | yes |
GO:0043254 | regulation of protein-containing complex assembly | 13.0597 | 5 | yes |
GO:0051493 | regulation of cytoskeleton organization | 13.0597 | 6 | yes |
GO:0010558 | negative regulation of macromolecule biosynthetic process | 12.6866 | 6 | yes |
GO:0010629 | negative regulation of gene expression | 12.6866 | 6 | yes |
GO:0030155 | regulation of cell adhesion | 12.6866 | 4 | yes |
GO:0031327 | negative regulation of cellular biosynthetic process | 12.6866 | 6 | yes |
GO:0060627 | regulation of vesicle-mediated transport | 12.6866 | 4 | yes |
GO:0070201 | regulation of establishment of protein localization | 12.6866 | 6 | yes |
GO:0080135 | regulation of cellular response to stress | 12.3134 | 4 | yes |
GO:1901699 | cellular response to nitrogen compound | 12.3134 | 4 | yes |
GO:0009896 | positive regulation of catabolic process | 12.3134 | 5 | yes |
GO:0071417 | cellular response to organonitrogen compound | 11.9403 | 4 | yes |
GO:0010942 | positive regulation of cell death | 11.9403 | 5 | yes |
GO:0031175 | neuron projection development | 11.9403 | 6 | yes |
GO:0060284 | regulation of cell development | 11.9403 | 5 | yes |
GO:0051241 | negative regulation of multicellular organismal process | 11.5672 | 4 | yes |
GO:0007167 | enzyme-linked receptor protein signaling pathway | 11.1940 | 4 | yes |
GO:0010563 | negative regulation of phosphorus metabolic process | 11.1940 | 6 | yes |
GO:0044089 | positive regulation of cellular component biogenesis | 11.1940 | 5 | yes |
GO:0045862 | positive regulation of proteolysis | 11.1940 | 7 | yes |
GO:0045936 | negative regulation of phosphate metabolic process | 11.1940 | 7 | yes |
GO:1901214 | regulation of neuron death | 10.8209 | 5 | yes |
GO:2000112 | regulation of cellular macromolecule biosynthetic process | 10.8209 | 6 | yes |
GO:0001558 | regulation of cell growth | 10.4478 | 4 | yes |
GO:1904951 | positive regulation of establishment of protein localization | 10.4478 | 6 | yes |
GO:0031346 | positive regulation of cell projection organization | 10.4478 | 6 | yes |
GO:0034097 | response to cytokine | 10.4478 | 4 | yes |
GO:0043086 | negative regulation of catalytic activity | 10.4478 | 4 | yes |
GO:2001233 | regulation of apoptotic signaling pathway | 10.0746 | 5 | yes |
GO:0051223 | regulation of protein transport | 10.0746 | 5 | yes |
GO:0061024 | membrane organization | 10.0746 | 4 | yes |
GO:0007169 | transmembrane receptor protein tyrosine kinase signaling pathway | 9.7015 | 5 | yes |
GO:0033993 | response to lipid | 9.7015 | 4 | yes |
GO:1901652 | response to peptide | 9.3284 | 4 | yes |
GO:0032386 | regulation of intracellular transport | 9.3284 | 5 | yes |
GO:0051093 | negative regulation of developmental process | 9.3284 | 4 | yes |
GO:0051345 | positive regulation of hydrolase activity | 9.3284 | 5 | yes |
GO:0018209 | peptidyl-serine modification | 8.9552 | 6 | yes |
GO:0030111 | regulation of Wnt signaling pathway | 8.9552 | 5 | yes |
GO:0045596 | negative regulation of cell differentiation | 8.9552 | 5 | yes |
GO:1902532 | negative regulation of intracellular signal transduction | 8.5821 | 6 | yes |
GO:1903050 | regulation of proteolysis involved in protein catabolic process | 8.5821 | 7 | yes |
GO:0018105 | peptidyl-serine phosphorylation | 8.5821 | 6 | yes |
GO:0031331 | positive regulation of cellular catabolic process | 8.5821 | 6 | yes |
GO:0045732 | positive regulation of protein catabolic process | 8.5821 | 6 | yes |
GO:0048638 | regulation of developmental growth | 8.5821 | 4 | yes |
GO:0071345 | cellular response to cytokine stimulus | 8.2090 | 5 | yes |
GO:0043393 | regulation of protein binding | 8.2090 | 4 | yes |
GO:0051046 | regulation of secretion | 8.2090 | 5 | yes |
GO:0051222 | positive regulation of protein transport | 8.2090 | 5 | yes |
GO:1901215 | negative regulation of neuron death | 7.8358 | 6 | yes |
GO:1903530 | regulation of secretion by cell | 7.8358 | 4 | yes |
GO:1900180 | regulation of protein localization to nucleus | 7.4627 | 6 | yes |
GO:2000058 | regulation of ubiquitin-dependent protein catabolic process | 7.4627 | 6 | yes |
GO:0031334 | positive regulation of protein-containing complex assembly | 7.4627 | 6 | yes |
GO:0043087 | regulation of GTPase activity | 7.4627 | 5 | yes |
GO:0050770 | regulation of axonogenesis | 7.4627 | 5 | yes |
GO:0061136 | regulation of proteasomal protein catabolic process | 7.4627 | 6 | yes |
GO:0010506 | regulation of autophagy | 7.0896 | 6 | yes |
GO:0045785 | positive regulation of cell adhesion | 7.0896 | 5 | yes |
GO:0051348 | negative regulation of transferase activity | 7.0896 | 5 | yes |
GO:0060828 | regulation of canonical Wnt signaling pathway | 7.0896 | 6 | yes |
GO:0071396 | cellular response to lipid | 6.7164 | 5 | yes |
GO:1901653 | cellular response to peptide | 6.7164 | 5 | yes |
GO:1903052 | positive regulation of proteolysis involved in protein catabolic process | 6.7164 | 8 | yes |
GO:0007005 | mitochondrion organization | 6.7164 | 5 | yes |
GO:2001234 | negative regulation of apoptotic signaling pathway | 6.7164 | 6 | yes |
GO:0032886 | regulation of microtubule-based process | 6.7164 | 4 | yes |
GO:2001236 | regulation of extrinsic apoptotic signaling pathway | 6.3433 | 6 | yes |
GO:0032388 | positive regulation of intracellular transport | 6.3433 | 5 | yes |
GO:0032434 | regulation of proteasomal ubiquitin-dependent protein catabolic process | 6.3433 | 7 | yes |
GO:0033157 | regulation of intracellular protein transport | 6.3433 | 6 | yes |
GO:0051099 | positive regulation of binding | 6.3433 | 4 | yes |
GO:0030516 | regulation of axon extension | 5.9701 | 5 | yes |
GO:0046777 | protein autophosphorylation | 5.9701 | 6 | yes |
GO:0061387 | regulation of extent of cell growth | 5.9701 | 5 | yes |
GO:0090316 | positive regulation of intracellular protein transport | 5.5970 | 6 | yes |
GO:1901800 | positive regulation of proteasomal protein catabolic process | 5.5970 | 7 | yes |
GO:2000060 | positive regulation of ubiquitin-dependent protein catabolic process | 5.5970 | 7 | yes |
GO:0018107 | peptidyl-threonine phosphorylation | 5.5970 | 6 | yes |
GO:0018210 | peptidyl-threonine modification | 5.5970 | 6 | yes |
GO:0051100 | negative regulation of binding | 5.5970 | 4 | yes |
GO:0051346 | negative regulation of hydrolase activity | 5.5970 | 5 | yes |
GO:0022411 | cellular component disassembly | 5.2239 | 4 | yes |
GO:0031333 | negative regulation of protein-containing complex assembly | 5.2239 | 6 | yes |
GO:0070507 | regulation of microtubule cytoskeleton organization | 5.2239 | 5 | yes |
GO:0006109 | regulation of carbohydrate metabolic process | 4.8507 | 5 | yes |
GO:2001237 | negative regulation of extrinsic apoptotic signaling pathway | 4.8507 | 7 | yes |
GO:0010721 | negative regulation of cell development | 4.8507 | 6 | yes |
GO:0010821 | regulation of mitochondrion organization | 4.8507 | 6 | yes |
GO:0015980 | energy derivation by oxidation of organic compounds | 4.8507 | 4 | yes |
GO:0032091 | negative regulation of protein binding | 4.8507 | 5 | yes |
GO:0043467 | regulation of generation of precursor metabolites and energy | 4.8507 | 5 | yes |
GO:0120032 | regulation of plasma membrane bounded cell projection assembly | 4.4776 | 6 | yes |
GO:1901216 | positive regulation of neuron death | 4.4776 | 6 | yes |
GO:1903828 | negative regulation of protein localization | 4.4776 | 5 | yes |
GO:0010810 | regulation of cell-substrate adhesion | 4.4776 | 5 | yes |
GO:0017157 | regulation of exocytosis | 4.4776 | 5 | yes |
GO:0032092 | positive regulation of protein binding | 4.4776 | 5 | yes |
GO:0032436 | positive regulation of proteasomal ubiquitin-dependent protein catabolic process | 4.4776 | 8 | yes |
GO:0046822 | regulation of nucleocytoplasmic transport | 4.4776 | 6 | yes |
GO:0060491 | regulation of cell projection assembly | 4.4776 | 5 | yes |
GO:0106027 | neuron projection organization | 4.1045 | 6 | yes |
GO:0001952 | regulation of cell-matrix adhesion | 4.1045 | 6 | yes |
GO:0043255 | regulation of carbohydrate biosynthetic process | 4.1045 | 5 | yes |
GO:0120034 | positive regulation of plasma membrane bounded cell projection assembly | 3.7313 | 6 | yes |
GO:0010675 | regulation of cellular carbohydrate metabolic process | 3.7313 | 5 | yes |
GO:0030178 | negative regulation of Wnt signaling pathway | 3.7313 | 6 | yes |
GO:0034976 | response to endoplasmic reticulum stress | 3.7313 | 4 | yes |
GO:0035303 | regulation of dephosphorylation | 3.7313 | 7 | yes |
GO:0043547 | positive regulation of GTPase activity | 3.7313 | 6 | yes |
GO:0045664 | regulation of neuron differentiation | 3.7313 | 5 | yes |
GO:0050773 | regulation of dendrite development | 3.7313 | 4 | yes |
GO:0090090 | negative regulation of canonical Wnt signaling pathway | 3.3582 | 7 | yes |
GO:2000113 | negative regulation of cellular macromolecule biosynthetic process | 3.3582 | 7 | yes |
GO:0032984 | protein-containing complex disassembly | 3.3582 | 5 | yes |
GO:0035304 | regulation of protein dephosphorylation | 3.3582 | 7 | yes |
GO:0051588 | regulation of neurotransmitter transport | 3.3582 | 5 | yes |
GO:1902115 | regulation of organelle assembly | 2.9851 | 5 | yes |
GO:1903305 | regulation of regulated secretory pathway | 2.9851 | 6 | yes |
GO:1904645 | response to amyloid-beta | 2.9851 | 5 | yes |
GO:1904646 | cellular response to amyloid-beta | 2.9851 | 6 | yes |
GO:0006112 | energy reserve metabolic process | 2.9851 | 5 | yes |
GO:0007006 | mitochondrial membrane organization | 2.9851 | 5 | yes |
GO:0010811 | positive regulation of cell-substrate adhesion | 2.9851 | 6 | yes |
GO:0032881 | regulation of polysaccharide metabolic process | 2.9851 | 5 | yes |
GO:0032885 | regulation of polysaccharide biosynthetic process | 2.9851 | 6 | yes |
GO:0046824 | positive regulation of nucleocytoplasmic transport | 2.9851 | 6 | yes |
GO:0046928 | regulation of neurotransmitter secretion | 2.9851 | 4 | yes |
GO:1900271 | regulation of long-term synaptic potentiation | 2.6119 | 4 | yes |
GO:0001954 | positive regulation of cell-matrix adhesion | 2.6119 | 7 | yes |
GO:0005976 | polysaccharide metabolic process | 2.6119 | 4 | yes |
GO:0005977 | glycogen metabolic process | 2.6119 | 6 | yes |
GO:0005979 | regulation of glycogen biosynthetic process | 2.6119 | 7 | yes |
GO:0006073 | cellular glucan metabolic process | 2.6119 | 5 | yes |
GO:0010921 | regulation of phosphatase activity | 2.6119 | 5 | yes |
GO:0010962 | regulation of glucan biosynthetic process | 2.6119 | 6 | yes |
GO:0043666 | regulation of phosphoprotein phosphatase activity | 2.6119 | 6 | yes |
GO:0044042 | glucan metabolic process | 2.6119 | 5 | yes |
GO:0044264 | cellular polysaccharide metabolic process | 2.6119 | 4 | yes |
GO:0048814 | regulation of dendrite morphogenesis | 2.6119 | 5 | yes |
GO:0060078 | regulation of postsynaptic membrane potential | 2.6119 | 4 | yes |
GO:0060079 | excitatory postsynaptic potential | 2.6119 | 5 | yes |
GO:0070873 | regulation of glycogen metabolic process | 2.6119 | 6 | yes |
GO:1901983 | regulation of protein acetylation | 2.2388 | 7 | yes |
GO:0001837 | epithelial to mesenchymal transition | 2.2388 | 5 | yes |
GO:0008286 | insulin receptor signaling pathway | 2.2388 | 6 | yes |
GO:2000300 | regulation of synaptic vesicle exocytosis | 2.2388 | 5 | yes |
GO:2000736 | regulation of stem cell differentiation | 2.2388 | 5 | yes |
GO:0046825 | regulation of protein export from nucleus | 2.2388 | 7 | yes |
GO:0048762 | mesenchymal cell differentiation | 2.2388 | 4 | yes |
GO:0050848 | regulation of calcium-mediated signaling | 2.2388 | 6 | yes |
GO:0097191 | extrinsic apoptotic signaling pathway | 1.8657 | 4 | yes |
GO:1904338 | regulation of dopaminergic neuron differentiation | 1.8657 | 6 | yes |
GO:0010508 | positive regulation of autophagy | 1.8657 | 7 | yes |
GO:0010822 | positive regulation of mitochondrion organization | 1.8657 | 7 | yes |
GO:0032526 | response to retinoic acid | 1.8657 | 4 | yes |
GO:0045665 | negative regulation of neuron differentiation | 1.8657 | 6 | yes |
GO:0071300 | cellular response to retinoic acid | 1.8657 | 5 | yes |
GO:0106056 | regulation of calcineurin-mediated signaling | 1.4925 | 7 | yes |
GO:0106057 | negative regulation of calcineurin-mediated signaling | 1.4925 | 8 | yes |
GO:1900034 | regulation of cellular response to heat | 1.4925 | 5 | yes |
GO:1900181 | negative regulation of protein localization to nucleus | 1.4925 | 6 | yes |
GO:1902041 | regulation of extrinsic apoptotic signaling pathway via death domain receptors | 1.4925 | 7 | yes |
GO:1902042 | negative regulation of extrinsic apoptotic signaling pathway via death domain receptors | 1.4925 | 8 | yes |
GO:1902117 | positive regulation of organelle assembly | 1.4925 | 6 | yes |
GO:1904779 | regulation of protein localization to centrosome | 1.4925 | 6 | yes |
GO:2000737 | negative regulation of stem cell differentiation | 1.4925 | 6 | yes |
GO:0046902 | regulation of mitochondrial membrane permeability | 1.4925 | 4 | yes |
GO:0050849 | negative regulation of calcium-mediated signaling | 1.4925 | 7 | yes |
GO:0070884 | regulation of calcineurin-NFAT signaling cascade | 1.4925 | 8 | yes |
GO:0070885 | negative regulation of calcineurin-NFAT signaling cascade | 1.4925 | 9 | yes |
GO:1901028 | regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway | 1.1194 | 5 | yes |
GO:1901984 | negative regulation of protein acetylation | 1.1194 | 8 | yes |
GO:1902017 | regulation of cilium assembly | 1.1194 | 6 | yes |
GO:1904339 | negative regulation of dopaminergic neuron differentiation | 1.1194 | 7 | yes |
GO:1904781 | positive regulation of protein localization to centrosome | 1.1194 | 6 | yes |
GO:1904886 | beta-catenin destruction complex disassembly | 1.1194 | 6 | yes |
GO:0006983 | ER overload response | 1.1194 | 4 | yes |
GO:2000074 | regulation of type B pancreatic cell development | 1.1194 | 6 | yes |
GO:0035305 | negative regulation of dephosphorylation | 1.1194 | 8 | yes |
GO:0045912 | negative regulation of carbohydrate metabolic process | 1.1194 | 5 | yes |
GO:0046827 | positive regulation of protein export from nucleus | 1.1194 | 7 | yes |
GO:0097192 | extrinsic apoptotic signaling pathway in absence of ligand | 0.7463 | 4 | yes |
GO:0150101 | regulation of microtubule anchoring at centrosome | 0.7463 | 6 | yes |
GO:1901030 | positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway | 0.7463 | 5 | yes |
GO:1903564 | regulation of protein localization to cilium | 0.7463 | 6 | yes |
GO:1903566 | positive regulation of protein localization to cilium | 0.7463 | 6 | yes |
GO:1905239 | regulation of canonical Wnt signaling pathway involved in osteoblast differentiation | 0.7463 | 7 | yes |
GO:1905240 | negative regulation of canonical Wnt signaling pathway involved in osteoblast differentiation | 0.7463 | 8 | yes |
GO:1905710 | positive regulation of membrane permeability | 0.7463 | 4 | yes |
GO:2000077 | negative regulation of type B pancreatic cell development | 0.7463 | 5 | yes |
GO:2000465 | regulation of glycogen (starch) synthase activity | 0.7463 | 5 | yes |
GO:2000466 | negative regulation of glycogen (starch) synthase activity | 0.7463 | 6 | yes |
GO:2000739 | regulation of mesenchymal stem cell differentiation | 0.7463 | 6 | yes |
GO:2000740 | negative regulation of mesenchymal stem cell differentiation | 0.7463 | 7 | yes |
GO:0010677 | negative regulation of cellular carbohydrate metabolic process | 0.7463 | 6 | yes |
GO:0010923 | negative regulation of phosphatase activity | 0.7463 | 6 | yes |
GO:0032515 | negative regulation of phosphoprotein phosphatase activity | 0.7463 | 7 | yes |
GO:0035308 | negative regulation of protein dephosphorylation | 0.7463 | 8 | yes |
GO:0035794 | positive regulation of mitochondrial membrane permeability | 0.7463 | 5 | yes |
GO:0036015 | response to interleukin-3 | 0.7463 | 5 | yes |
GO:0036016 | cellular response to interleukin-3 | 0.7463 | 6 | yes |
GO:0045719 | negative regulation of glycogen biosynthetic process | 0.7463 | 7 | yes |
GO:0045724 | positive regulation of cilium assembly | 0.7463 | 7 | yes |
GO:0070874 | negative regulation of glycogen metabolic process | 0.7463 | 6 | yes |
Disease
Term | Name | % | Distance from top the of the tree | Annotated in GSK3B_HUMAN |
---|---|---|---|---|
DOID:331 | central nervous system disease | 2.9851 | 3 | no |
DOID:1289 | neurodegenerative disease | 1.4925 | 4 | no |
DOID:936 | brain disease | 1.4925 | 4 | no |
DOID:231 | motor neuron disease | 1.1194 | 5 | no |
DOID:65 | connective tissue disease | 1.1194 | 3 | no |
DOID:114 | heart disease | 1.1194 | 3 | no |
DOID:332 | amyotrophic lateral sclerosis | 0.7463 | 6 | no |
DOID:0080001 | bone disease | 0.7463 | 4 | no |
DOID:0080006 | bone development disease | 0.7463 | 5 | no |
DOID:574 | peripheral nervous system disease | 0.7463 | 3 | no |
DOID:870 | neuropathy | 0.7463 | 4 | no |
DOID:0080000 | muscular disease | 0.7463 | 3 | no |
DOID:423 | myopathy | 0.7463 | 5 | no |
DOID:66 | muscle tissue disease | 0.7463 | 4 | no |
DOID:9884 | muscular dystrophy | 0.7463 | 6 | no |
DOID:0050686 | organ system cancer | 0.7463 | 3 | no |
DOID:0081062 | diabetes | 0.7463 | 5 | no |
DOID:2978 | carbohydrate metabolic disorder | 0.7463 | 3 | no |
DOID:4194 | glucose metabolism disease | 0.7463 | 4 | no |
DOID:9351 | diabetes mellitus | 0.7463 | 6 | no |
DOID:9352 | type 2 diabetes mellitus | 0.7463 | 7 | no |
DOID:0050700 | cardiomyopathy | 0.7463 | 4 | no |
DOID:0060036 | intrinsic cardiomyopathy | 0.7463 | 5 | no |
DOID:12930 | dilated cardiomyopathy | 0.7463 | 6 | no |
DOID:1247 | blood coagulation disease | 0.7463 | 3 | no |
DOID:2218 | blood platelet disease | 0.7463 | 4 | no |
Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
---|---|---|---|---|
PKHO1_HUMAN | [view interactions] | Low throughput | no | no |
CRBN_HUMAN | [view interactions] | Low throughput | no | yes |
CADH1_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
EYA1_HUMAN | [view interactions] | Low throughput | no | no |
MTG8_HUMAN | [view interactions] | Low throughput | no | yes |
ARRB2_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
SNAI2_HUMAN | [view interactions] | Low throughput | no | yes |
NF2L2_HUMAN | [view interactions] | Low throughput | no | yes |
DISC1_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
RN220_HUMAN | [view interactions] | Low throughput | no | yes |
SYUA_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
M3K4_HUMAN | [view interactions] | Low throughput | no | yes |
DVL1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
HS71B_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
NOTC1_HUMAN | [view interactions] | Low throughput | no | yes |
HS71A_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
HSP74_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
SOX10_HUMAN | [view interactions] | Low throughput | no | yes |
PSN1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
SRBP1_HUMAN | [view interactions] | Low throughput | no | yes |
NFKB1_HUMAN | [view interactions] | Low throughput | no | yes |
KPCA_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
AXIN2_HUMAN | [view interactions] | Low throughput | no | yes |
RICTR_HUMAN | [view interactions] | Low throughput | no | yes |
PRGC1_HUMAN | [view interactions] | Low throughput | no | no |
PHLP1_HUMAN | [view interactions] | Low throughput | no | yes |
C2TA_HUMAN | [view interactions] | Low throughput | no | no |
ARRB1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
NCOA3_HUMAN | [view interactions] | Low throughput | no | yes |
CSN8_HUMAN | [view interactions] | Low throughput | no | yes |
PDE4D_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
CREB1_HUMAN | [view interactions] | Low throughput | no | yes |
PRKDC_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
AKT3_HUMAN | [view interactions] | Low throughput | no | yes |
NF2L3_HUMAN | [view interactions] | Low throughput | no | no |
KS6A1_HUMAN | [view interactions] | Low throughput | no | yes |
CCDC6_HUMAN | [view interactions] | Low throughput | no | yes |
KLF2_HUMAN | [view interactions] | Low throughput | no | yes |
AKA11_HUMAN | [view interactions] | Low throughput | no | yes |
HDAC4_HUMAN | [view interactions] | Low throughput | no | yes |
CR3L3_HUMAN | [view interactions] | Low throughput | no | no |
TRAF6_HUMAN | [view interactions] | Low throughput | no | yes |
PCAT1_HUMAN | [view interactions] | Low throughput | no | yes |
B2CL1_HUMAN | [view interactions] | Low throughput | no | yes |
CEBPD_HUMAN | [view interactions] | Low throughput | no | no |
B2LA1_HUMAN | [view interactions] | Low throughput | no | no |
ILK_HUMAN | [view interactions] | Low throughput | no | no |
PIAS1_HUMAN | [view interactions] | Low throughput | no | yes |
GFI1_HUMAN | [view interactions] | Low throughput | no | yes |
PSME3_HUMAN | [view interactions] | Low throughput | no | yes |
STAT2_HUMAN | [view interactions] | Low throughput | no | yes |
PDPK1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
PTPA_HUMAN | [view interactions] | Low throughput | no | yes |
SQSTM_HUMAN | [view interactions] | Low throughput | no | yes |
AREL1_HUMAN | [view interactions] | Low throughput | no | no |
TBK1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
UBE3A_HUMAN | [view interactions] | Low throughput | no | yes |
PD1L1_HUMAN | [view interactions] | Low throughput | no | no |
CDX2_HUMAN | [view interactions] | Low throughput | no | no |
MCL1_HUMAN | [view interactions] | Low throughput | no | yes |
NDRG1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
PCM1_HUMAN | [view interactions] | Low throughput | no | yes |
FBX7_HUMAN | [view interactions] | Low throughput | no | yes |
TBG1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
KDM1A_HUMAN | [view interactions] | Low throughput | no | yes |
EP2A2_HUMAN | [view interactions] | Low throughput | no | no |
GID8_HUMAN | [view interactions] | Low throughput | no | yes |
UBP48_HUMAN | [view interactions] | Low throughput | no | yes |
ZN281_HUMAN | [view interactions] | Low throughput | no | no |
SP1_HUMAN | [view interactions] | Low throughput | no | yes |
BIP_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
STRAP_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
IRS1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
PRC1_HUMAN | [view interactions] | Low throughput | no | yes |
PAR10_HUMAN | [view interactions] | Low throughput | no | yes |
PARP3_HUMAN | [view interactions] | Low throughput | no | yes |
FAP20_HUMAN | [view interactions] | Low throughput | no | no |
CD5R1_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
CDK5_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
TRI29_HUMAN | [view interactions] | Low throughput | no | no |
MACF1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
RELB_HUMAN | [view interactions] | Low throughput | no | yes |
PP2AA_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
TF65_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
DACT1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
DAB2P_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
PPID_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
DZIP1_HUMAN | [view interactions] | Low throughput | no | yes |
NIN_HUMAN | [view interactions] | Low throughput | no | no |
AXIN1_HUMAN | [view interactions] | Low throughput | no | yes |
NBR1_HUMAN | [view interactions] | Low throughput | no | yes |
DEAF1_HUMAN | [view interactions] | Low throughput | no | yes |
SGK3_HUMAN | [view interactions] | Low throughput | no | yes |
ATX3_HUMAN | [view interactions] | Low throughput | no | yes |
BEX1_HUMAN | [view interactions] | Low throughput | no | yes |
AKT2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
YBOX1_HUMAN | [view interactions] | Low throughput | no | yes |
YBOX3_HUMAN | [view interactions] | Low throughput | no | yes |
GYS1_HUMAN | [view interactions] | Low throughput | no | yes |
TSC2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
MK01_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
SMAD1_HUMAN | [view interactions] | Low throughput | no | yes |
GSK3B_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
SFPQ_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
EI2BE_HUMAN | [view interactions] | Low throughput | no | yes |
BAX_HUMAN | [view interactions] | Low throughput | no | yes |
PTN1_HUMAN | [view interactions] | Low throughput | no | yes |
DPYL2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
KPCZ_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
CCNE1_HUMAN | [view interactions] | Low throughput | no | no |
NEMO_HUMAN | [view interactions] | Low throughput | no | yes |
JUN_HUMAN | [view interactions] | Low throughput | no | yes |
GRB14_HUMAN | [view interactions] | Low throughput | no | yes |
DNM1L_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
P53_HUMAN | [view interactions] | Low throughput | no | no |
HS90A_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
MYH9_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
ANDR_HUMAN | [view interactions] | Low throughput | no | no |
MUC1_HUMAN | [view interactions] | Low throughput | no | no |
NOTC2_HUMAN | [view interactions] | Low throughput | no | yes |
FAK1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
TSC1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
FBW1A_HUMAN | [view interactions] | Low throughput | no | yes |
E2F1_HUMAN | [view interactions] | Low throughput | no | yes |
CABYR_HUMAN | [view interactions] | Low throughput | no | no |
ANKR6_HUMAN | [view interactions] | Low throughput | no | yes |
B2L12_HUMAN | [view interactions] | Low throughput | no | yes |
SMAD3_HUMAN | [view interactions] | Low throughput | no | yes |
BICD1_HUMAN | [view interactions] | Low throughput | no | yes |
SNCAP_HUMAN | [view interactions] | Low throughput | no | no |
MYC_HUMAN | [view interactions] | Low throughput | no | yes |
KLF5_HUMAN | [view interactions] | Low throughput | no | yes |
SNAI1_HUMAN | [view interactions] | Low throughput | no | yes |
CEBPB_HUMAN | [view interactions] | Low throughput | no | no |
ATF3_HUMAN | [view interactions] | Low throughput | no | yes |
AMMR1_HUMAN | [view interactions] | Low throughput | no | no |
SMUF2_HUMAN | [view interactions] | Low throughput | no | yes |
IPP2_HUMAN | [view interactions] | Low throughput | no | no |
CTND1_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
IRF1_HUMAN | [view interactions] | Low throughput | no | yes |
PP1G_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
BCL3_HUMAN | [view interactions] | Low throughput | no | yes |
SET_HUMAN | [view interactions] | Low throughput | no | yes |
STYK1_HUMAN | [view interactions] | Low throughput | no | yes |
NOTC3_HUMAN | [view interactions] | Low throughput | no | yes |
AKT1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
MRTFA_HUMAN | [view interactions] | Low throughput | no | yes |
CLSPN_HUMAN | [view interactions] | Low throughput | no | no |
CTNB1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
CTND2_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
HSF1_HUMAN | [view interactions] | Low throughput | no | yes |
1433Z_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
LRP6_HUMAN | [view interactions] | Low throughput | no | yes |
UBP7_HUMAN | [view interactions] | Low throughput | no | yes |
KAPCA_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
HDAC6_HUMAN | [view interactions] | Low throughput | no | yes |
TNAP3_HUMAN | [view interactions] | Low throughput | no | yes |
LRRK2_HUMAN | [view interactions] | Low throughput | no | yes |
UBR5_HUMAN | [view interactions] | Low throughput | no | no |
A4_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
NS1BP_HUMAN | [view interactions] | Low throughput | no | yes |
STK11_HUMAN | [view interactions] | Low throughput | no | yes |
SOX9_HUMAN | [view interactions] | Low throughput | no | no |
APC_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
RASF1_HUMAN | [view interactions] | Low throughput | no | yes |
TAZ_HUMAN | [view interactions] | Low throughput | no | yes |
PRS7_HUMAN | [view interactions] | Low throughput | no | yes |
SP7_HUMAN | [view interactions] | Low throughput | no | no |
MDM2_HUMAN | [view interactions] | Low throughput | no | yes |
TOP2A_HUMAN | [view interactions] | Low throughput | no | no |
TARA_HUMAN | [view interactions] | Low throughput | no | yes |
AURKA_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
DYRK2_HUMAN | [view interactions] | Low throughput | no | yes |
FBXW7_HUMAN | [view interactions] | Low throughput | no | yes |
TELT_HUMAN | [view interactions] | Low throughput | no | no |
2A5D_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
FXL21_HUMAN | [view interactions] | Low throughput | no | no |
M3K1_HUMAN | [view interactions] | Low throughput | no | yes |
SPI1_HUMAN | [view interactions] | Low throughput | no | no |
XIAP_HUMAN | [view interactions] | Low throughput | no | yes |
RNF43_HUMAN | [view interactions] | Low throughput | no | yes |
BIRC2_HUMAN | [view interactions] | Low throughput | no | yes |
BIRC3_HUMAN | [view interactions] | Low throughput | no | no |
NUB1_HUMAN | [view interactions] | Low throughput | no | no |
KLHL1_HUMAN | [view interactions] | Low throughput | no | no |
CSK_HUMAN | [view interactions] | Low throughput | no | yes |
DDIT4_HUMAN | [view interactions] | Low throughput | no | yes |
FRAT1_HUMAN | [view interactions] | Low throughput | no | yes |
NF2L1_HUMAN | [view interactions] | Low throughput | no | yes |
TAU_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
CSF3R_HUMAN | [view interactions] | Low throughput | no | yes |
IPYR_HUMAN | [view interactions] | Low throughput | no | yes |
SIGIR_HUMAN | [view interactions] | Low throughput | no | no |
PP1B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
OGT1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
EED_HUMAN | [view interactions] | High throughput | no | yes |
HAX1_HUMAN | [view interactions] | High throughput | no | no |
XPO1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
NUFP1_HUMAN | [view interactions] | High throughput | no | yes |
ITLN1_HUMAN | [view interactions] | High throughput | no | no |
MAZ_HUMAN | [view interactions] | High throughput | no | yes |
PP2BC_HUMAN | [view interactions] | High throughput | no | yes |
PRC2C_HUMAN | [view interactions] | High throughput | no | yes |
RCAN2_HUMAN | [view interactions] | High throughput | no | yes |
E41L3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
MTRR_HUMAN | [view interactions] | High throughput | no | yes |
GSKIP_HUMAN | [view interactions] | High throughput | no | yes |
NDUV3_HUMAN | [view interactions] | High throughput | no | yes |
CADM1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
MPZL1_HUMAN | [view interactions] | High throughput | no | yes |
RBM33_HUMAN | [view interactions] | High throughput | no | yes |
RPA34_HUMAN | [view interactions] | High throughput | no | yes |
CDC37_HUMAN | [view interactions] | High throughput | no | yes |
ZCH14_HUMAN | [view interactions] | High throughput | no | no |
CLAP2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
SO4A1_HUMAN | [view interactions] | High throughput | no | yes |
SC16A_HUMAN | [view interactions] | High throughput | no | yes |
E41LB_HUMAN | [view interactions] | High throughput | no | yes |
RL39_HUMAN | [view interactions] | High throughput | no | no |
RBM26_HUMAN | [view interactions] | High throughput | no | yes |
APBB1_HUMAN | [view interactions] | High throughput | no | yes |
SYNP2_HUMAN | [view interactions] | High throughput | no | yes |
SHAN3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
DDX23_HUMAN | [view interactions] | High throughput | no | yes |
UBX2B_HUMAN | [view interactions] | High throughput | no | no |
GBG12_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
TLR3_HUMAN | [view interactions] | High throughput | no | yes |
RBM28_HUMAN | [view interactions] | High throughput | no | yes |
DDX18_HUMAN | [view interactions] | High throughput | no | yes |
M3K7_HUMAN | [view interactions] | High throughput | no | yes |
DDX47_HUMAN | [view interactions] | High throughput | no | yes |
TAB1_HUMAN | [view interactions] | High throughput | no | yes |
RT27_HUMAN | [view interactions] | High throughput | no | yes |
TAB2_HUMAN | [view interactions] | High throughput | no | yes |
KRI1_HUMAN | [view interactions] | High throughput | no | yes |
TCAM2_HUMAN | [view interactions] | High throughput | no | no |
CENPV_HUMAN | [view interactions] | High throughput | no | yes |
DREB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
AINX_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
M3K2_HUMAN | [view interactions] | High throughput | no | yes |
PLEC_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
NFAC1_HUMAN | [view interactions] | High throughput | no | no |
RRP5_HUMAN | [view interactions] | High throughput | no | yes |
NFAC2_HUMAN | [view interactions] | High throughput | no | yes |
RRP1B_HUMAN | [view interactions] | High throughput | no | yes |
FOXM1_HUMAN | [view interactions] | High throughput | no | yes |
FZD1_HUMAN | [view interactions] | High throughput | no | yes |
DSG2_HUMAN | [view interactions] | High throughput | no | no |
PTN11_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
TLE3_HUMAN | [view interactions] | High throughput | no | yes |
MP2K7_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
BASP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
WDTC1_HUMAN | [view interactions] | High throughput | no | yes |
ILKAP_HUMAN | [view interactions] | High throughput | no | yes |
GBB1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
KC1A_HUMAN | [view interactions] | High throughput | no | yes |
SRP09_HUMAN | [view interactions] | High throughput | no | no |
IPP2B_HUMAN | [view interactions] | High throughput | no | no |
KI67_HUMAN | [view interactions] | High throughput | no | no |
PRPS2_HUMAN | [view interactions] | High throughput | no | no |
FETUA_HUMAN | [view interactions] | High throughput | no | no |
SAMH1_HUMAN | [view interactions] | High throughput | no | yes |
FERM2_HUMAN | [view interactions] | High throughput | no | yes |
MYO1B_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
DEF5_HUMAN | [view interactions] | High throughput | no | no |
HTRA2_HUMAN | [view interactions] | High throughput | no | yes |
MYO1C_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
RCAN1_HUMAN | [view interactions] | High throughput | no | yes |
TPPP_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
AAPK2_HUMAN | [view interactions] | High throughput | no | yes |
DKK3_HUMAN | [view interactions] | High throughput | no | yes |
NHLC2_HUMAN | [view interactions] | High throughput | no | yes |
BRSK1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
U2AF1_HUMAN | [view interactions] | High throughput | no | yes |
VWA8_HUMAN | [view interactions] | High throughput | no | yes |
CLK4_HUMAN | [view interactions] | High throughput | no | yes |
TSKS_HUMAN | [view interactions] | High throughput | no | no |
SYNE3_HUMAN | [view interactions] | High throughput | no | no |
MKNK2_HUMAN | [view interactions] | High throughput | no | yes |
CACO2_HUMAN | [view interactions] | High throughput | no | yes |
SRPK3_HUMAN | [view interactions] | High throughput | no | no |
SMYD2_HUMAN | [view interactions] | High throughput | no | yes |
RGS22_HUMAN | [view interactions] | High throughput | no | no |
DHX36_HUMAN | [view interactions] | High throughput | no | yes |
ACLY_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
HECD1_HUMAN | [view interactions] | High throughput | no | yes |
MYCN_HUMAN | [view interactions] | High throughput | no | no |
IF2B1_HUMAN | [view interactions] | High throughput | no | no |
RECQ4_HUMAN | [view interactions] | High throughput | no | yes |
EWS_HUMAN | [view interactions] | High throughput | no | yes |
FIP1_HUMAN | [view interactions] | High throughput | no | yes |
SMN_HUMAN | [view interactions] | High throughput | no | yes |
MP2K5_HUMAN | [view interactions] | High throughput | no | yes |
RPB2_HUMAN | [view interactions] | High throughput | no | yes |
ATX1_HUMAN | [view interactions] | High throughput | no | yes |
DHB4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
RU17_HUMAN | [view interactions] | High throughput | no | yes |
SF3B1_HUMAN | [view interactions] | High throughput | no | yes |
ANXA2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
H1T_HUMAN | [view interactions] | High throughput | no | no |
LDHB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
ELP1_HUMAN | [view interactions] | High throughput | no | yes |
CAZA1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
RPF2_HUMAN | [view interactions] | High throughput | no | yes |
RLA0_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
DDX5_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
LRC59_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
GEMI4_HUMAN | [view interactions] | High throughput | no | yes |
MDHM_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
FUS_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
MDHC_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
QPCTL_HUMAN | [view interactions] | High throughput | no | yes |
NACAM_HUMAN | [view interactions] | High throughput | no | no |
SF3A1_HUMAN | [view interactions] | High throughput | no | yes |
EF1D_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
DDX20_HUMAN | [view interactions] | High throughput | no | no |
PDLI1_HUMAN | [view interactions] | High throughput | no | yes |
XPO6_HUMAN | [view interactions] | High throughput | no | yes |
CNN2_HUMAN | [view interactions] | High throughput | no | no |
ALDR_HUMAN | [view interactions] | High throughput | no | no |
ROA2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
PDXK_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
PTBP3_HUMAN | [view interactions] | High throughput | no | no |
ENOA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
GALE_HUMAN | [view interactions] | High throughput | no | no |
DACT2_HUMAN | [view interactions] | High throughput | no | yes |
RPR1B_HUMAN | [view interactions] | High throughput | no | yes |
YAP1_HUMAN | [view interactions] | High throughput | no | yes |
APEX1_HUMAN | [view interactions] | High throughput | no | yes |
AIMP1_HUMAN | [view interactions] | High throughput | no | yes |
SSRA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
LMAN2_HUMAN | [view interactions] | High throughput | no | yes |
CYFP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
OTUB1_HUMAN | [view interactions] | High throughput | no | yes |
FMR1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
PDIP2_HUMAN | [view interactions] | High throughput | no | no |
FXR1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
HMOX2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
HCN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
NDUA9_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
NCKP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
TCPB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
TNIK_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
PDIA1_HUMAN | [view interactions] | High throughput | no | yes |
AGAP2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
G6PI_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
SYGP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
TCPD_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
RS18_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
TCPQ_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
RL6_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
TCPH_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
RL13_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
G6PD_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
PRS37_HUMAN | [view interactions] | High throughput | no | no |
CH60_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
REN3A_HUMAN | [view interactions] | High throughput | no | yes |
TRFL_HUMAN | [view interactions] | High throughput | no | no |
TCPA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
ACRO_HUMAN | [view interactions] | High throughput | no | no |
IMDH2_HUMAN | [view interactions] | High throughput | no | yes |
ZG16B_HUMAN | [view interactions] | High throughput | no | no |
AL1A3_HUMAN | [view interactions] | High throughput | no | yes |
TLR9_HUMAN | [view interactions] | High throughput | no | no |
PTBP1_HUMAN | [view interactions] | High throughput | no | no |
SPICE_HUMAN | [view interactions] | High throughput | no | yes |
SPB4_HUMAN | [view interactions] | High throughput | no | no |
PDIA3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
S10A8_HUMAN | [view interactions] | High throughput | no | no |
FKBP4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
KRBA1_HUMAN | [view interactions] | High throughput | no | no |
PROF1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
CAP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
LZTS2_HUMAN | [view interactions] | High throughput | no | no |
PERM_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
TCPZ_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
M3K11_HUMAN | [view interactions] | High throughput | no | yes |
H31_HUMAN | [view interactions] | High throughput | no | yes |
SERA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
NONO_HUMAN | [view interactions] | High throughput | no | yes |
H4_HUMAN | [view interactions] | High throughput | no | yes |
CPNE3_HUMAN | [view interactions] | High throughput | no | yes |
PROX2_HUMAN | [view interactions] | High throughput | no | no |
H33_HUMAN | [view interactions] | High throughput | no | yes |
NP1L1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
PRUN1_HUMAN | [view interactions] | High throughput | no | no |
H2B1K_HUMAN | [view interactions] | High throughput | no | yes |
RCC2_HUMAN | [view interactions] | High throughput | no | no |
VTA1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
H2A1D_HUMAN | [view interactions] | High throughput | no | yes |
TRXR1_HUMAN | [view interactions] | High throughput | no | yes |
ZBED3_HUMAN | [view interactions] | High throughput | no | yes |
HSP72_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
TBA1B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
HS90B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
SYYC_HUMAN | [view interactions] | High throughput | no | yes |
FOG1_HUMAN | [view interactions] | High throughput | no | yes |
HPT_HUMAN | [view interactions] | High throughput | no | no |
PRS4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
WTIP_HUMAN | [view interactions] | High throughput | no | no |
GELS_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
UGDH_HUMAN | [view interactions] | High throughput | no | no |
ACBG1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
GGCT_HUMAN | [view interactions] | High throughput | no | yes |
HNRPK_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
ACL6B_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
DMBT1_HUMAN | [view interactions] | High throughput | no | no |
COPD_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
ADAP1_HUMAN | [view interactions] | High throughput | no | yes |
CATG_HUMAN | [view interactions] | High throughput | no | no |
PACN2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
ASGL1_HUMAN | [view interactions] | High throughput | no | yes |
CATA_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
PAK2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
ATIF1_HUMAN | [view interactions] | High throughput | no | yes |
CASPE_HUMAN | [view interactions] | High throughput | no | no |
GRP75_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
BPIB1_HUMAN | [view interactions] | High throughput | no | no |
LKHA4_HUMAN | [view interactions] | High throughput | no | yes |
CREL2_HUMAN | [view interactions] | High throughput | no | yes |
ARGI1_HUMAN | [view interactions] | High throughput | no | no |
LMNB1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
ANXA1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
SYRC_HUMAN | [view interactions] | High throughput | no | yes |
BRX1_HUMAN | [view interactions] | High throughput | no | no |
SYFB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
5MP1_HUMAN | [view interactions] | High throughput | no | no |
ABCE1_HUMAN | [view interactions] | High throughput | no | yes |
ADIRF_HUMAN | [view interactions] | High throughput | no | no |
CMC2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
VPS51_HUMAN | [view interactions] | High throughput | no | yes |
FUBP1_HUMAN | [view interactions] | High throughput | no | yes |
ERG28_HUMAN | [view interactions] | High throughput | no | yes |
TRI25_HUMAN | [view interactions] | High throughput | no | yes |
SYNE4_HUMAN | [view interactions] | High throughput | no | yes |
RFA1_HUMAN | [view interactions] | High throughput | no | yes |
CEBPZ_HUMAN | [view interactions] | High throughput | no | no |
IF2B3_HUMAN | [view interactions] | High throughput | no | no |
CENPB_HUMAN | [view interactions] | High throughput | no | yes |
AMPB_HUMAN | [view interactions] | High throughput | no | yes |
CHD3_HUMAN | [view interactions] | High throughput | no | yes |
MOES_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
TETN_HUMAN | [view interactions] | High throughput | no | no |
PABP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
CSAD_HUMAN | [view interactions] | High throughput | no | yes |
LMNA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
CYTM_HUMAN | [view interactions] | High throughput | no | no |
DUS9_HUMAN | [view interactions] | High throughput | no | no |
CAN2_HUMAN | [view interactions] | High throughput | no | no |
ACBP_HUMAN | [view interactions] | High throughput | no | yes |
DYL1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
GUAA_HUMAN | [view interactions] | High throughput | no | no |
DCTN3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
FRAT2_HUMAN | [view interactions] | High throughput | no | no |
SRC8_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
DEF1_HUMAN | [view interactions] | High throughput | no | no |
PDIA4_HUMAN | [view interactions] | High throughput | no | yes |
DHX34_HUMAN | [view interactions] | High throughput | no | no |
TRAP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
DJC13_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
DDX3X_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
DNMT1_HUMAN | [view interactions] | High throughput | no | no |
ECHA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
DNM3L_HUMAN | [view interactions] | High throughput | no | yes |
CAN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
EF1A1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
FOXO1_HUMAN | [view interactions] | High throughput | no | yes |
TTL12_HUMAN | [view interactions] | High throughput | no | yes |
EF1G_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
CCND1_HUMAN | [view interactions] | High throughput | no | yes |
ACSL3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
U5S1_HUMAN | [view interactions] | High throughput | no | yes |
KPCB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
GARS_HUMAN | [view interactions] | High throughput | no | yes |
4EBP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
SEPT9_HUMAN | [view interactions] | High throughput | no | no |
ENTP6_HUMAN | [view interactions] | High throughput | no | yes |
LAP2A_HUMAN | [view interactions] | High throughput | no | yes |
FA83D_HUMAN | [view interactions] | High throughput | no | no |
STON1_HUMAN | [view interactions] | High throughput | no | yes |
PYRG1_HUMAN | [view interactions] | High throughput | no | no |
FBN3_HUMAN | [view interactions] | High throughput | no | no |
TRAK1_HUMAN | [view interactions] | High throughput | no | yes |
GPDM_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
FEN1_HUMAN | [view interactions] | High throughput | no | yes |
CP131_HUMAN | [view interactions] | High throughput | no | no |
VPS35_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
FIBP_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
KDIS_HUMAN | [view interactions] | High throughput | no | yes |
GFPT1_HUMAN | [view interactions] | High throughput | no | no |
FKB14_HUMAN | [view interactions] | High throughput | no | yes |
BI2L1_HUMAN | [view interactions] | High throughput | no | yes |
DC1I2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
MTOR_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
SWP70_HUMAN | [view interactions] | High throughput | no | no |
SRP72_HUMAN | [view interactions] | High throughput | no | yes |
G3P_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
DCP1A_HUMAN | [view interactions] | High throughput | no | yes |
DPP3_HUMAN | [view interactions] | High throughput | no | no |
GBP2_HUMAN | [view interactions] | High throughput | no | yes |
HAUS4_HUMAN | [view interactions] | High throughput | no | yes |
GLU2B_HUMAN | [view interactions] | High throughput | no | yes |
GIPC1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
SPAG5_HUMAN | [view interactions] | High throughput | no | yes |
ACPH_HUMAN | [view interactions] | High throughput | no | yes |
CXB5_HUMAN | [view interactions] | High throughput | no | no |
F193B_HUMAN | [view interactions] | High throughput | no | yes |
NDUS1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
GBB2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
CC138_HUMAN | [view interactions] | High throughput | no | yes |
TERA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
GPR39_HUMAN | [view interactions] | High throughput | no | yes |
EDC3_HUMAN | [view interactions] | High throughput | no | yes |
IMB1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
IGHM_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
ATG2B_HUMAN | [view interactions] | High throughput | no | no |
GANAB_HUMAN | [view interactions] | High throughput | no | yes |
IGS21_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
NU205_HUMAN | [view interactions] | High throughput | no | no |
TFR1_HUMAN | [view interactions] | High throughput | no | yes |
DRC9_HUMAN | [view interactions] | High throughput | no | yes |
DLG5_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
PYGL_HUMAN | [view interactions] | High throughput | no | yes |
FUBP2_HUMAN | [view interactions] | High throughput | no | yes |
ALMS1_HUMAN | [view interactions] | High throughput | no | no |
PSMD2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
P33MX_HUMAN | [view interactions] | High throughput | no | yes |
DCP1B_HUMAN | [view interactions] | High throughput | no | yes |
SSRP1_HUMAN | [view interactions] | High throughput | no | yes |
CAMP3_HUMAN | [view interactions] | High throughput | no | no |
MA7D3_HUMAN | [view interactions] | High throughput | no | no |
MCM3_HUMAN | [view interactions] | High throughput | no | no |
KINH_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
CRBG3_HUMAN | [view interactions] | High throughput | no | no |
MCM6_HUMAN | [view interactions] | High throughput | no | yes |
LMO4_HUMAN | [view interactions] | High throughput | no | yes |
KANK2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
AP2B1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
LC7L2_HUMAN | [view interactions] | High throughput | no | yes |
CE350_HUMAN | [view interactions] | High throughput | no | yes |
PDC6I_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
MAP4_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
VP13D_HUMAN | [view interactions] | High throughput | no | no |
COPB2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
MASP1_HUMAN | [view interactions] | High throughput | no | no |
PP2BA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
COPG1_HUMAN | [view interactions] | High throughput | no | yes |
MED24_HUMAN | [view interactions] | High throughput | no | no |
DYST_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
SYMC_HUMAN | [view interactions] | High throughput | no | yes |
OGA_HUMAN | [view interactions] | High throughput | no | yes |
ECHB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
NIBA2_HUMAN | [view interactions] | High throughput | no | no |
MICA1_HUMAN | [view interactions] | High throughput | no | yes |
KAP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
RIR1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
M1IP1_HUMAN | [view interactions] | High throughput | no | yes |
ECD_HUMAN | [view interactions] | High throughput | no | yes |
CSDE1_HUMAN | [view interactions] | High throughput | no | yes |
EM55_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
CEP43_HUMAN | [view interactions] | High throughput | no | no |
NSUN2_HUMAN | [view interactions] | High throughput | no | yes |
MTF2_HUMAN | [view interactions] | High throughput | no | no |
CE152_HUMAN | [view interactions] | High throughput | no | yes |
MOGS_HUMAN | [view interactions] | High throughput | no | yes |
NAT9_HUMAN | [view interactions] | High throughput | no | no |
OFD1_HUMAN | [view interactions] | High throughput | no | yes |
C1TC_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
TONSL_HUMAN | [view interactions] | High throughput | no | no |
TRAK2_HUMAN | [view interactions] | High throughput | no | yes |
VINC_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
NRBP_HUMAN | [view interactions] | High throughput | no | yes |
WDR62_HUMAN | [view interactions] | High throughput | no | no |
UBA1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
NSF1C_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
CP110_HUMAN | [view interactions] | High throughput | no | yes |
NUCL_HUMAN | [view interactions] | High throughput | no | yes |
F264_HUMAN | [view interactions] | High throughput | no | no |
PP6R1_HUMAN | [view interactions] | High throughput | no | no |
XPO2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
PIM2_HUMAN | [view interactions] | High throughput | no | no |
ERBIN_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
CTNA1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
APR_HUMAN | [view interactions] | High throughput | no | yes |
LTV1_HUMAN | [view interactions] | High throughput | no | yes |
IPO5_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
PTN_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
ENTR1_HUMAN | [view interactions] | High throughput | no | no |
HS105_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
SYQ_HUMAN | [view interactions] | High throughput | no | yes |
LRC49_HUMAN | [view interactions] | High throughput | no | no |
PARP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
RAI1_HUMAN | [view interactions] | High throughput | no | yes |
TPGS1_HUMAN | [view interactions] | High throughput | no | no |
PUR2_HUMAN | [view interactions] | High throughput | no | yes |
SUH_HUMAN | [view interactions] | High throughput | no | yes |
LAR1B_HUMAN | [view interactions] | High throughput | no | no |
SND1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
RL36L_HUMAN | [view interactions] | High throughput | no | no |
PP6R3_HUMAN | [view interactions] | High throughput | no | yes |
HNRPU_HUMAN | [view interactions] | High throughput | no | yes |
RLA1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
PEX5_HUMAN | [view interactions] | High throughput | no | yes |
EIF3B_HUMAN | [view interactions] | High throughput | no | yes |
RS2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
HAUS5_HUMAN | [view interactions] | High throughput | no | yes |
IPO7_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
RSU1_HUMAN | [view interactions] | High throughput | no | no |
TANK_HUMAN | [view interactions] | High throughput | no | yes |
TIF1B_HUMAN | [view interactions] | High throughput | no | yes |
RXRA_HUMAN | [view interactions] | High throughput | no | yes |
SYAC_HUMAN | [view interactions] | High throughput | no | yes |
S30BP_HUMAN | [view interactions] | High throughput | no | yes |
BAG6_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
PSMD1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
SLAP1_HUMAN | [view interactions] | High throughput | no | yes |
DEC1_HUMAN | [view interactions] | High throughput | no | no |
NALP2_HUMAN | [view interactions] | High throughput | no | no |
SPTN4_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
FBW1B_HUMAN | [view interactions] | High throughput | no | yes |
ITB1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
TLE1_HUMAN | [view interactions] | High throughput | no | yes |
CJ090_HUMAN | [view interactions] | High throughput | no | no |
ICAL_HUMAN | [view interactions] | High throughput | no | yes |
TMM44_HUMAN | [view interactions] | High throughput | no | no |
TEKT5_HUMAN | [view interactions] | High throughput | no | no |
HXK1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
MYL6_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
EIF3C_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
TBA1A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
BCCIP_HUMAN | [view interactions] | High throughput | no | no |
AP1B1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
UB2D1_HUMAN | [view interactions] | High throughput | no | yes |
SYIM_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
UBR1_HUMAN | [view interactions] | High throughput | no | yes |
RS15_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
MVP_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
UBXN6_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
PSMD8_HUMAN | [view interactions] | High throughput | no | yes |
ERAP1_HUMAN | [view interactions] | High throughput | no | yes |
UFM1_HUMAN | [view interactions] | High throughput | no | yes |
GOLM2_HUMAN | [view interactions] | High throughput | no | yes |
VIME_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
CKLF2_HUMAN | [view interactions] | High throughput | no | no |
FAS_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
WSB1_HUMAN | [view interactions] | High throughput | no | yes |
LYAR_HUMAN | [view interactions] | High throughput | no | no |
IQGA1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
XPP1_HUMAN | [view interactions] | High throughput | no | yes |
PKRI1_HUMAN | [view interactions] | High throughput | no | no |
MYOF_HUMAN | [view interactions] | High throughput | no | yes |
ZHX1_HUMAN | [view interactions] | High throughput | no | no |
HNRPM_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
IF4G1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
ZN135_HUMAN | [view interactions] | High throughput | no | yes |
SMG7_HUMAN | [view interactions] | High throughput | no | no |
FLNA_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
ZN227_HUMAN | [view interactions] | High throughput | no | yes |
PYR1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
ZN746_HUMAN | [view interactions] | High throughput | no | no |
CLH1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
FZD5_HUMAN | [view interactions] | High throughput | no | yes |
ZO1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
BHE40_HUMAN | [view interactions] | High throughput | no | yes |
KAP2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
UBC_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
BHE41_HUMAN | [view interactions] | High throughput | no | no |
ALBU_HUMAN | [view interactions] | High throughput | no | no |
CSK2B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
KPYM_HUMAN | [view interactions] | High throughput | no | yes |
HSP7C_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
ACTN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
EF2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
ENPL_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
PSA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
4F2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
TRAF2_HUMAN | [view interactions] | High throughput | no | yes |
MET_HUMAN | [view interactions] | High throughput | no | yes |
CAPR1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
LMBRL_HUMAN | [view interactions] | High throughput | no | no |
CSN2_HUMAN | [view interactions] | High throughput | no | yes |
PKHA4_HUMAN | [view interactions] | High throughput | no | yes |
CSN5_HUMAN | [view interactions] | High throughput | no | yes |
ELAV1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
BCAR1_HUMAN | [view interactions] | High throughput | no | yes |
KCC2A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
SC6A4_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
EGLN3_HUMAN | [view interactions] | High throughput | no | no |
LYSC_HUMAN | [view interactions] | High throughput | no | no |
ZER1_HUMAN | [view interactions] | High throughput | no | no |
REPS2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
TAF5_HUMAN | [view interactions] | High throughput | no | yes |
CDA7L_HUMAN | [view interactions] | High throughput | no | yes |
NUD18_HUMAN | [view interactions] | High throughput | no | no |
AP2A_HUMAN | [view interactions] | High throughput | no | no |
SBSN_HUMAN | [view interactions] | High throughput | no | no |
EDEM1_HUMAN | [view interactions] | High throughput | no | yes |
NT5D3_HUMAN | [view interactions] | High throughput | no | no |
ACACB_HUMAN | [view interactions] | High throughput | no | no |
KAPCB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
APBA1_HUMAN | [view interactions] | High throughput | no | no |
SHRPN_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
FOXP3_HUMAN | [view interactions] | High throughput | no | no |
CART_HUMAN | [view interactions] | High throughput | no | yes |
RFIP2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
GSK3A_HUMAN | [view interactions] | High throughput | no | yes |
ZN273_HUMAN | [view interactions] | High throughput | no | no |
ZNRD2_HUMAN | [view interactions] | High throughput | no | yes |
BCOR_HUMAN | [view interactions] | High throughput | no | no |
FKBP5_HUMAN | [view interactions] | High throughput | no | yes |
ARHGB_HUMAN | [view interactions] | High throughput | no | yes |
CHIP_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
KAP0_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
ARC_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
PP1A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
HECW2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
PAR6A_HUMAN | [view interactions] | Computational | no | yes |
CCND2_HUMAN | [view interactions] | Computational | no | yes |
KLC2_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
DVL2_HUMAN | [view interactions] | Computational | no | yes |
WNT8B_HUMAN | [view interactions] | Computational | no | no |
DPYL5_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
KS6B1_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
CREB5_HUMAN | [view interactions] | Computational | no | no |
TCHP_HUMAN | [view interactions] | Computational | no | yes |
ATF4_HUMAN | [view interactions] | Computational | no | no |
GYS2_HUMAN | [view interactions] | Computational | no | no |
KLC1_HUMAN | [view entry] [view interactions] | Computational | yes | no |
TBCD7_HUMAN | [view interactions] | Computational | no | no |
WNT3_HUMAN | [view interactions] | Computational | no | no |
CANB1_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
DPYL3_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
TBP_HUMAN | [view interactions] | Computational | no | yes |
RPAB2_HUMAN | [view interactions] | Computational | no | yes |
MP2K1_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
PPIF_HUMAN | [view interactions] | Computational | no | no |
PARD3_HUMAN | [view interactions] | Computational | no | yes |
PP2BB_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
PIN1_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
KLC4_HUMAN | [view interactions] | Computational | no | yes |
KAPCG_HUMAN | [view interactions] | Computational | no | no |
TAF1C_HUMAN | [view interactions] | Computational | no | no |
CDK4_HUMAN | [view interactions] | Computational | no | no |
RPAC2_HUMAN | [view interactions] | Computational | no | no |
DDX21_HUMAN | [view interactions] | Computational | no | yes |
KC1G1_HUMAN | [view interactions] | Computational | no | no |
RPA2_HUMAN | [view interactions] | Computational | no | no |
SIAH1_HUMAN | [view interactions] | Computational | no | yes |
CREB3_HUMAN | [view interactions] | Computational | no | no |
DVL3_HUMAN | [view interactions] | Computational | no | yes |
KIF5A_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
RPAB3_HUMAN | [view interactions] | Computational | no | yes |
GLI3_HUMAN | [view interactions] | Computational | no | yes |
KC1E_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
TAF1B_HUMAN | [view interactions] | Computational | no | no |
PLXA3_HUMAN | [view entry] [view interactions] | Computational | yes | no |
2A5A_HUMAN | [view interactions] | Computational | no | yes |
GLI2_HUMAN | [view interactions] | Computational | no | yes |
CDK6_HUMAN | [view interactions] | Computational | no | yes |
NRP1_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
SMCA5_HUMAN | [view interactions] | Computational | no | yes |
RPA12_HUMAN | [view interactions] | Computational | no | yes |
RPAB1_HUMAN | [view interactions] | Computational | no | yes |
GCR_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
CCND3_HUMAN | [view interactions] | Computational | no | no |
2AAA_HUMAN | [view entry] [view interactions] | Computational | yes | no |
MBB1A_HUMAN | [view interactions] | Computational | no | yes |
CYBP_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
FAK2_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
MP2K2_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
SEM3A_HUMAN | [view interactions] | Computational | no | no |
DPYL1_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
TAF1D_HUMAN | [view interactions] | Computational | no | yes |
PAR6G_HUMAN | [view interactions] | Computational | no | no |
CR3L4_HUMAN | [view interactions] | Computational | no | no |
TAF1A_HUMAN | [view interactions] | Computational | no | yes |
RPAB4_HUMAN | [view interactions] | Computational | no | no |
SUFU_HUMAN | [view interactions] | Computational | no | yes |
PLXA4_HUMAN | [view entry] [view interactions] | Computational | yes | no |
PPR3A_HUMAN | [view interactions] | Computational | no | no |
WNT2_HUMAN | [view interactions] | Computational | no | no |
RPA1_HUMAN | [view interactions] | Computational | no | yes |
P63_HUMAN | [view interactions] | Computational | no | no |
WNT3A_HUMAN | [view entry] [view interactions] | Computational | yes | no |
PAR6B_HUMAN | [view interactions] | Computational | no | no |
DPYL4_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
PLXA2_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
LRP5_HUMAN | [view interactions] | Computational | no | yes |
APCL_HUMAN | [view entry] [view interactions] | Computational | yes | no |
RAF1_HUMAN | [view entry] [view interactions] | Computational | yes | no |
KIF5C_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
KLC3_HUMAN | [view interactions] | Computational | no | no |
FYN_HUMAN | [view entry] [view interactions] | Computational | yes | no |
MAX_HUMAN | [view interactions] | Computational | no | yes |
CR3L2_HUMAN | [view interactions] | Computational | no | yes |
NFAC3_HUMAN | [view interactions] | Computational | no | no |
KC1G2_HUMAN | [view interactions] | Computational | no | yes |
CR3L1_HUMAN | [view interactions] | Computational | no | yes |
PLXA1_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
WNT1_HUMAN | [view interactions] | Computational | no | no |
RPA43_HUMAN | [view interactions] | Computational | no | yes |
KC1D_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
CUL1_HUMAN | [view interactions] | Computational | no | yes |
RPA49_HUMAN | [view interactions] | Computational | no | yes |
KC1AL_HUMAN | [view interactions] | Computational | no | no |
PROC_HUMAN | [view interactions] | Computational | no | no |
CANB2_HUMAN | [view interactions] | Computational | no | no |
BAZ1B_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
PRIO_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
RPAB5_HUMAN | [view interactions] | Computational | no | no |