Features Interactions Isoform Disease Linear motifs Fingerprint Network All partners

IPO7_HUMAN

(Microbial infection) Mediates the nuclear import of HIV-1 reverse transcription complex (RTC) integrase. Binds and mediates the nuclear import of HIV-1 Rev. [View more on UniProt]

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No data found.

No annotated instance was found. To search for linear motifs, use the ELM prediction server.

Molecular function

Term Name % Distance from the top of the tree Annotated in IPO7_HUMAN
GO:0003723 RNA binding 39.0625 4 no
GO:0019900 kinase binding 26.5625 4 no
GO:0019901 protein kinase binding 25.0000 5 no
GO:0030695 GTPase regulator activity 10.9375 4 yes
GO:0031267 small GTPase binding 9.3750 5 yes
GO:0051020 GTPase binding 9.3750 4 yes

Biological process

Term Name % Distance from top the of the tree Annotated in IPO7_HUMAN
GO:0048522 positive regulation of cellular process 54.6875 4 no
GO:0031323 regulation of cellular metabolic process 51.5625 4 yes
GO:0048523 negative regulation of cellular process 48.4375 4 yes
GO:0080090 regulation of primary metabolic process 48.4375 4 yes
GO:0051171 regulation of nitrogen compound metabolic process 46.8750 4 yes
GO:0060255 regulation of macromolecule metabolic process 46.8750 4 yes
GO:0010646 regulation of cell communication 40.6250 4 no
GO:0006996 organelle organization 40.6250 4 no
GO:0009893 positive regulation of metabolic process 39.0625 4 no
GO:0010604 positive regulation of macromolecule metabolic process 35.9375 5 no
GO:0031325 positive regulation of cellular metabolic process 35.9375 5 no
GO:0051128 regulation of cellular component organization 35.9375 4 no
GO:0009966 regulation of signal transduction 35.9375 4 no
GO:0051246 regulation of protein metabolic process 34.3750 5 yes
GO:0010468 regulation of gene expression 34.3750 5 no
GO:0022607 cellular component assembly 34.3750 4 no
GO:0019220 regulation of phosphate metabolic process 32.8125 6 yes
GO:0051174 regulation of phosphorus metabolic process 32.8125 5 yes
GO:0051173 positive regulation of nitrogen compound metabolic process 32.8125 5 no
GO:0009892 negative regulation of metabolic process 31.2500 4 yes
GO:0031399 regulation of protein modification process 31.2500 6 yes
GO:1902531 regulation of intracellular signal transduction 31.2500 5 no
GO:0008104 protein localization 29.6875 4 yes
GO:0031324 negative regulation of cellular metabolic process 29.6875 5 yes
GO:0042325 regulation of phosphorylation 29.6875 7 yes
GO:0051049 regulation of transport 29.6875 4 no
GO:0001932 regulation of protein phosphorylation 28.1250 7 yes
GO:0010605 negative regulation of macromolecule metabolic process 28.1250 5 yes
GO:0009889 regulation of biosynthetic process 28.1250 4 no
GO:0031326 regulation of cellular biosynthetic process 28.1250 5 no
GO:0051172 negative regulation of nitrogen compound metabolic process 26.5625 5 yes
GO:0071702 organic substance transport 26.5625 4 yes
GO:0071310 cellular response to organic substance 26.5625 4 no
GO:0010941 regulation of cell death 26.5625 4 no
GO:0051338 regulation of transferase activity 25.0000 4 yes
GO:0010556 regulation of macromolecule biosynthetic process 25.0000 5 no
GO:0010647 positive regulation of cell communication 25.0000 5 no
GO:0023056 positive regulation of signaling 25.0000 4 no
GO:0051247 positive regulation of protein metabolic process 25.0000 6 no
GO:0015031 protein transport 23.4375 4 yes
GO:0071705 nitrogen compound transport 23.4375 4 yes
GO:0032880 regulation of protein localization 23.4375 5 no
GO:0060341 regulation of cellular localization 23.4375 4 no
GO:0019219 regulation of nucleobase-containing compound metabolic process 23.4375 5 no
GO:0043933 protein-containing complex organization 23.4375 4 no
GO:0042981 regulation of apoptotic process 23.4375 6 no
GO:0043067 regulation of programmed cell death 23.4375 5 no
GO:0048584 positive regulation of response to stimulus 23.4375 4 no
GO:0060548 negative regulation of cell death 23.4375 5 no
GO:0006886 intracellular protein transport 21.8750 4 yes
GO:0043549 regulation of kinase activity 21.8750 5 yes
GO:0009967 positive regulation of signal transduction 21.8750 5 no
GO:0051248 negative regulation of protein metabolic process 20.3125 6 yes
GO:0051252 regulation of RNA metabolic process 20.3125 5 no
GO:0042127 regulation of cell population proliferation 20.3125 4 no
GO:0043085 positive regulation of catalytic activity 20.3125 4 no
GO:0033043 regulation of organelle organization 20.3125 5 no
GO:0007010 cytoskeleton organization 20.3125 5 no
GO:0043066 negative regulation of apoptotic process 20.3125 7 no
GO:0043069 negative regulation of programmed cell death 20.3125 6 no
GO:0033365 protein localization to organelle 18.7500 5 yes
GO:0045859 regulation of protein kinase activity 18.7500 6 yes
GO:0051726 regulation of cell cycle 15.6250 4 yes
GO:0031400 negative regulation of protein modification process 14.0625 7 yes
GO:0072594 establishment of protein localization to organelle 14.0625 4 yes
GO:0010563 negative regulation of phosphorus metabolic process 12.5000 6 yes
GO:0043086 negative regulation of catalytic activity 12.5000 4 yes
GO:0045936 negative regulation of phosphate metabolic process 12.5000 7 yes
GO:0006913 nucleocytoplasmic transport 10.9375 5 yes
GO:0051169 nuclear transport 10.9375 4 yes
GO:0051348 negative regulation of transferase activity 10.9375 5 yes
GO:0001933 negative regulation of protein phosphorylation 9.3750 8 yes
GO:0006606 protein import into nucleus 9.3750 5 yes
GO:0034504 protein localization to nucleus 9.3750 6 yes
GO:0042326 negative regulation of phosphorylation 9.3750 8 yes
GO:0051170 import into nucleus 9.3750 6 yes
GO:0071900 regulation of protein serine/threonine kinase activity 9.3750 7 yes
GO:0006469 negative regulation of protein kinase activity 7.8125 7 yes
GO:0033673 negative regulation of kinase activity 7.8125 6 yes
GO:0071901 negative regulation of protein serine/threonine kinase activity 6.2500 8 yes
GO:1904029 regulation of cyclin-dependent protein kinase activity 6.2500 5 yes
GO:0000079 regulation of cyclin-dependent protein serine/threonine kinase activity 4.6875 6 yes
GO:0045736 negative regulation of cyclin-dependent protein serine/threonine kinase activity 4.6875 6 yes
GO:0045786 negative regulation of cell cycle 4.6875 5 yes
GO:1904030 negative regulation of cyclin-dependent protein kinase activity 4.6875 6 yes

Disease

Term Name % Distance from top the of the tree Annotated in IPO7_HUMAN
DOID:331 central nervous system disease 6.2500 3 no
DOID:1289 neurodegenerative disease 4.6875 4 no
DOID:231 motor neuron disease 4.6875 5 no
DOID:332 amyotrophic lateral sclerosis 3.1250 6 no
DOID:0111198 autosomal dominant distal hereditary motor neuronopathy 3.1250 7 no
DOID:12377 spinal muscular atrophy 3.1250 6 no
Uniprot ID Details Highest evidence Localizing into PSD HPA (protein expression in neurons)
SRP19_HUMAN [view interactions] Low throughput no yes
RL23A_HUMAN [view entry] [view interactions] Low throughput yes yes
RAN_HUMAN [view entry] [view interactions] Low throughput yes no
AKTIP_HUMAN [view interactions] Low throughput no yes
GLI1_HUMAN [view interactions] Low throughput no no
THA_HUMAN [view interactions] Low throughput no yes
TRAF6_HUMAN [view interactions] High throughput no yes
MYC_HUMAN [view interactions] High throughput no yes
STK4_HUMAN [view interactions] High throughput no yes
CSAG1_HUMAN [view interactions] High throughput no no
CSAG2_HUMAN [view interactions] High throughput no no
LIMS1_HUMAN [view interactions] High throughput no yes
DCTN1_HUMAN [view entry] [view interactions] High throughput yes yes
SPICE_HUMAN [view interactions] High throughput no yes
RPGR1_HUMAN [view interactions] High throughput no no
CEP19_HUMAN [view interactions] High throughput no no
FBRL_HUMAN [view interactions] High throughput no yes
NECD_HUMAN [view interactions] High throughput no no
DYRK2_HUMAN [view interactions] High throughput no yes
DUS5_HUMAN [view interactions] High throughput no no
KLF15_HUMAN [view interactions] High throughput no yes
UBC_HUMAN [view entry] [view interactions] High throughput yes yes
RN146_HUMAN [view interactions] High throughput no yes
SIR7_HUMAN [view interactions] High throughput no yes
FBX25_HUMAN [view interactions] High throughput no no
CDK2_HUMAN [view interactions] High throughput no yes
FBX6_HUMAN [view interactions] High throughput no yes
CAH9_HUMAN [view interactions] High throughput no no
MET18_HUMAN [view interactions] High throughput no yes
EGFR_HUMAN [view interactions] High throughput no no
STAU1_HUMAN [view entry] [view interactions] High throughput yes yes
MDM2_HUMAN [view interactions] High throughput no yes
CCDC8_HUMAN [view interactions] High throughput no yes
RING2_HUMAN [view interactions] High throughput no yes
EED_HUMAN [view interactions] High throughput no yes
RIC3_HUMAN [view interactions] High throughput no yes
NUSAP_HUMAN [view interactions] High throughput no no
VSIG2_HUMAN [view interactions] High throughput no no
PNKD_HUMAN [view entry] [view interactions] High throughput yes yes
XRP2_HUMAN [view entry] [view interactions] High throughput yes no
EDA_HUMAN [view interactions] High throughput no no
KS6B2_HUMAN [view interactions] High throughput no yes
UNK_HUMAN [view interactions] High throughput no yes
NTRK1_HUMAN [view interactions] High throughput no yes
IF16_HUMAN [view interactions] High throughput no no
MCM2_HUMAN [view interactions] High throughput no no
KSR1_HUMAN [view interactions] High throughput no yes
CAF1A_HUMAN [view interactions] High throughput no yes
RAD18_HUMAN [view interactions] High throughput no yes
PTPRE_HUMAN [view interactions] High throughput no no
UXS1_HUMAN [view interactions] High throughput no yes
P85A_HUMAN [view interactions] High throughput no yes
FACD2_HUMAN [view interactions] High throughput no no
TRI25_HUMAN [view interactions] High throughput no yes
G3BP1_HUMAN [view interactions] High throughput no yes
BRCA1_HUMAN [view interactions] High throughput no yes
TES_HUMAN [view interactions] High throughput no yes
ZN598_HUMAN [view interactions] High throughput no no
IQGA1_HUMAN [view entry] [view interactions] High throughput yes no
PPP6_HUMAN [view interactions] High throughput no yes
TXTP_HUMAN [view entry] [view interactions] High throughput yes no
KC1A_HUMAN [view interactions] High throughput no yes
RASK_HUMAN [view entry] [view interactions] High throughput yes no
TPTE_HUMAN [view interactions] High throughput no no
PRP8_HUMAN [view interactions] High throughput no yes
U5S1_HUMAN [view interactions] High throughput no yes
AAR2_HUMAN [view interactions] High throughput no no
PIHD1_HUMAN [view interactions] High throughput no yes
SOCS2_HUMAN [view interactions] High throughput no yes
RNF4_HUMAN [view interactions] High throughput no yes
RIOK1_HUMAN [view interactions] High throughput no yes
ESR2_HUMAN [view interactions] High throughput no no
HECD1_HUMAN [view interactions] High throughput no yes
SNAI1_HUMAN [view interactions] High throughput no yes
WWOX_HUMAN [view interactions] High throughput no yes
EZH2_HUMAN [view interactions] High throughput no no
RECQ4_HUMAN [view interactions] High throughput no yes
DCPS_HUMAN [view interactions] High throughput no yes
TXNIP_HUMAN [view interactions] High throughput no no
GRWD1_HUMAN [view interactions] High throughput no no
VIR_HUMAN [view interactions] High throughput no yes
PHB1_HUMAN [view entry] [view interactions] High throughput yes yes
TM41B_HUMAN [view interactions] High throughput no yes
ATX1_HUMAN [view interactions] High throughput no yes
ATX3_HUMAN [view interactions] High throughput no yes
DUS23_HUMAN [view interactions] High throughput no yes
PTN1_HUMAN [view interactions] High throughput no yes
PTN21_HUMAN [view interactions] High throughput no yes
GSK3B_HUMAN [view entry] [view interactions] High throughput yes yes
ARAF_HUMAN [view interactions] High throughput no yes
BIRC3_HUMAN [view interactions] High throughput no no
LMBRL_HUMAN [view interactions] High throughput no no
RGS14_HUMAN [view entry] [view interactions] High throughput yes yes
CTBP2_HUMAN [view interactions] High throughput no no
PKHA4_HUMAN [view interactions] High throughput no yes
YAP1_HUMAN [view interactions] High throughput no yes
TFCP2_HUMAN [view interactions] High throughput no no
SMAD1_HUMAN [view interactions] High throughput no yes
LRC31_HUMAN [view interactions] High throughput no no
CTRO_HUMAN [view entry] [view interactions] High throughput yes yes
ANLN_HUMAN [view interactions] High throughput no yes
CHM4B_HUMAN [view entry] [view interactions] High throughput yes yes
CHM4C_HUMAN [view interactions] High throughput no yes
ECT2_HUMAN [view interactions] High throughput no no
KIF23_HUMAN [view interactions] High throughput no yes
HNRH1_HUMAN [view entry] [view interactions] High throughput yes yes
BRD4_HUMAN [view interactions] High throughput no yes
SYVN1_HUMAN [view interactions] High throughput no yes
TIM14_HUMAN [view entry] [view interactions] High throughput yes yes
DJC15_HUMAN [view interactions] High throughput no no
ASXL1_HUMAN [view interactions] High throughput no no
RIN3_HUMAN [view interactions] High throughput no yes
DDRGK_HUMAN [view entry] [view interactions] High throughput yes yes
T126A_HUMAN [view entry] [view interactions] High throughput yes yes
CDX1_HUMAN [view interactions] High throughput no no
KI2L4_HUMAN [view interactions] High throughput no no
MTLR_HUMAN [view interactions] High throughput no no
CA210_HUMAN [view interactions] High throughput no yes
CA115_HUMAN [view interactions] High throughput no no
P3IP1_HUMAN [view interactions] High throughput no no
NPIB6_HUMAN [view interactions] High throughput no yes
H12_HUMAN [view interactions] High throughput no yes
RL15_HUMAN [view entry] [view interactions] High throughput yes no
H15_HUMAN [view interactions] High throughput no no
SEC62_HUMAN [view interactions] High throughput no yes
F234A_HUMAN [view interactions] High throughput no yes
GA2L2_HUMAN [view interactions] High throughput no no
EFNB1_HUMAN [view interactions] High throughput no yes
RL18_HUMAN [view entry] [view interactions] High throughput yes yes
HMGN1_HUMAN [view interactions] High throughput no yes
REPI1_HUMAN [view interactions] High throughput no yes
FA43A_HUMAN [view interactions] High throughput no no
TPST2_HUMAN [view interactions] High throughput no yes
BTNL9_HUMAN [view interactions] High throughput no no
RM35_HUMAN [view interactions] High throughput no no
H14_HUMAN [view interactions] High throughput no yes
PHYD1_HUMAN [view interactions] High throughput no no
F174A_HUMAN [view interactions] High throughput no yes
RL36L_HUMAN [view interactions] High throughput no no
ZSC31_HUMAN [view interactions] High throughput no yes
S1PR1_HUMAN [view interactions] High throughput no no
RL35_HUMAN [view entry] [view interactions] High throughput yes yes
MAP7_HUMAN [view interactions] High throughput no yes
EP300_HUMAN [view interactions] High throughput no yes
FBXW7_HUMAN [view interactions] High throughput no yes
NRP1_HUMAN [view entry] [view interactions] High throughput yes yes
BASI_HUMAN [view entry] [view interactions] High throughput yes no
RHOF_HUMAN [view interactions] High throughput no no
RND2_HUMAN [view interactions] High throughput no no
VATF_HUMAN [view interactions] High throughput no yes
CDX2_HUMAN [view interactions] High throughput no no
H10_HUMAN [view interactions] High throughput no yes
NP1L1_HUMAN [view entry] [view interactions] High throughput yes yes
SAFB2_HUMAN [view interactions] High throughput no yes
TIF1B_HUMAN [view interactions] High throughput no yes
ZN629_HUMAN [view interactions] High throughput no no
H1X_HUMAN [view interactions] High throughput no yes
NP1L4_HUMAN [view entry] [view interactions] High throughput yes yes
ZN768_HUMAN [view interactions] High throughput no yes
HXA10_HUMAN [view interactions] High throughput no no
NEST_HUMAN [view interactions] High throughput no no
IMA1_HUMAN [view entry] [view interactions] High throughput yes yes
RAGP1_HUMAN [view entry] [view interactions] High throughput yes yes
NSA2_HUMAN [view interactions] High throughput no yes
RANG_HUMAN [view interactions] High throughput no no
RL19_HUMAN [view entry] [view interactions] High throughput yes yes
WEE1_HUMAN [view interactions] High throughput no yes
RIT1_HUMAN [view interactions] High throughput no yes
ITB3_HUMAN [view entry] [view interactions] High throughput yes no
PTEN_HUMAN [view entry] [view interactions] High throughput yes yes
IGBP1_HUMAN [view interactions] High throughput no yes
ACPH_HUMAN [view interactions] High throughput no yes
CAND1_HUMAN [view entry] [view interactions] High throughput yes no
RNZ2_HUMAN [view interactions] High throughput no yes
HARS1_HUMAN [view interactions] High throughput no yes
HS71L_HUMAN [view entry] [view interactions] High throughput yes no
HS74L_HUMAN [view entry] [view interactions] High throughput yes no
SYK_HUMAN [view interactions] High throughput no yes
NFRKB_HUMAN [view interactions] High throughput no yes
PFD5_HUMAN [view interactions] High throughput no yes
RNH2A_HUMAN [view interactions] High throughput no no
TNPO1_HUMAN [view entry] [view interactions] High throughput yes yes
TR112_HUMAN [view interactions] High throughput no yes
HS90B_HUMAN [view entry] [view interactions] High throughput yes yes
HSP7C_HUMAN [view entry] [view interactions] High throughput yes yes
HSPB1_HUMAN [view entry] [view interactions] High throughput yes no
IPO5_HUMAN [view entry] [view interactions] High throughput yes yes
IPO9_HUMAN [view interactions] High throughput no no
MPCP_HUMAN [view entry] [view interactions] High throughput yes no
MPP10_HUMAN [view interactions] High throughput no yes
PPM1G_HUMAN [view interactions] High throughput no no
ANM1_HUMAN [view interactions] High throughput no yes
IMB1_HUMAN [view entry] [view interactions] High throughput yes yes
RL5_HUMAN [view entry] [view interactions] High throughput yes yes
SLX4_HUMAN [view interactions] High throughput no yes
TRI14_HUMAN [view interactions] High throughput no yes
UBP49_HUMAN [view interactions] High throughput no yes
GBF1_HUMAN [view interactions] High throughput no yes
AIRE_HUMAN [view interactions] High throughput no no
DPPA3_HUMAN [view interactions] High throughput no no
IQCB1_HUMAN [view interactions] High throughput no no
RHDF2_HUMAN [view interactions] High throughput no yes
FTM_HUMAN [view interactions] High throughput no yes
SMG7_HUMAN [view interactions] High throughput no no
MK06_HUMAN [view interactions] High throughput no yes
CTIF_HUMAN [view interactions] High throughput no yes
ILK_HUMAN [view interactions] High throughput no no
RN183_HUMAN [view interactions] High throughput no no
NU188_HUMAN [view interactions] High throughput no yes
LEG9_HUMAN [view interactions] High throughput no yes
RBP2_HUMAN [view interactions] High throughput no yes
GCR_HUMAN [view entry] [view interactions] High throughput yes yes
ASPM_HUMAN [view interactions] High throughput no no
DNJB7_HUMAN [view interactions] High throughput no no
VPS16_HUMAN [view entry] [view interactions] High throughput yes yes
DNJC1_HUMAN [view interactions] High throughput no yes
LIMA1_HUMAN [view entry] [view interactions] High throughput yes no
DNJC2_HUMAN [view interactions] High throughput no yes
NU153_HUMAN [view interactions] High throughput no yes
CENPA_HUMAN [view interactions] High throughput no no
HDAC6_HUMAN [view interactions] High throughput no yes
COX8A_HUMAN [view interactions] High throughput no yes
CAZA2_HUMAN [view entry] [view interactions] High throughput yes yes
DIRA3_HUMAN [view interactions] High throughput no yes
MD2L1_HUMAN [view interactions] High throughput no no
PCNT_HUMAN [view interactions] High throughput no yes
NU107_HUMAN [view interactions] High throughput no no
RL31_HUMAN [view entry] [view interactions] High throughput yes yes
CE162_HUMAN [view interactions] High throughput no yes
ZN330_HUMAN [view interactions] High throughput no yes
LCA5_HUMAN [view interactions] High throughput no no
MLP3B_HUMAN [view interactions] High throughput no yes
ADIP_HUMAN [view interactions] High throughput no yes
NBR1_HUMAN [view interactions] High throughput no yes
VTI1B_HUMAN [view entry] [view interactions] High throughput yes yes
CACO2_HUMAN [view interactions] High throughput no yes
5HT2C_HUMAN [view interactions] High throughput no no
SQSTM_HUMAN [view interactions] High throughput no yes
SIGL1_HUMAN [view interactions] High throughput no no
SYNPO_HUMAN [view entry] [view interactions] High throughput yes no
PACC1_HUMAN [view interactions] High throughput no no
CMTD1_HUMAN [view entry] [view interactions] High throughput yes yes
ACM3_HUMAN [view entry] [view interactions] High throughput yes yes
PE2R3_HUMAN [view interactions] High throughput no no
FZD10_HUMAN [view interactions] High throughput no no
HP1B3_HUMAN [view interactions] High throughput no yes
PD1L1_HUMAN [view interactions] High throughput no no
AKIP_HUMAN [view interactions] High throughput no yes
ZBT38_HUMAN [view interactions] High throughput no no
LRRK2_HUMAN [view interactions] High throughput no yes
HD_HUMAN [view entry] [view interactions] High throughput yes yes
RAC1_HUMAN [view entry] [view interactions] High throughput yes no
BAD_HUMAN [view entry] [view interactions] High throughput yes yes
SHC1_HUMAN [view entry] [view interactions] High throughput yes yes
SOX2_HUMAN [view interactions] High throughput no yes
1433F_HUMAN [view entry] [view interactions] High throughput yes yes
VCAM1_HUMAN [view interactions] High throughput no no
H2B1M_HUMAN [view interactions] High throughput no yes
GRB2_HUMAN [view entry] [view interactions] High throughput yes yes
1433Z_HUMAN [view entry] [view interactions] High throughput yes yes
RS6_HUMAN [view entry] [view interactions] High throughput yes yes
NCBP3_HUMAN [view interactions] High throughput no yes
P2RY6_HUMAN [view interactions] High throughput no no
TN13B_HUMAN [view interactions] High throughput no no
ERBB4_HUMAN [view entry] [view interactions] High throughput yes yes
FYN_HUMAN [view entry] [view interactions] High throughput yes no
HTRA4_HUMAN [view interactions] High throughput no no
DISC1_HUMAN [view entry] [view interactions] High throughput yes no
AAPK2_HUMAN [view interactions] High throughput no yes
KS6A2_HUMAN [view interactions] High throughput no yes
MAST1_HUMAN [view interactions] High throughput no yes
PRIO_HUMAN [view entry] [view interactions] High throughput yes yes
CFTR_HUMAN [view interactions] High throughput no no
CDC5L_HUMAN [view interactions] High throughput no yes
STING_HUMAN [view interactions] High throughput no yes
ANGI_HUMAN [view interactions] High throughput no no
RYBP_HUMAN [view interactions] High throughput no no
NEMO_HUMAN [view interactions] High throughput no yes
TNR1B_HUMAN [view interactions] High throughput no no
TRADD_HUMAN [view interactions] High throughput no yes
IPO4_HUMAN [view interactions] Computational no no
EGR1_HUMAN [view interactions] Computational no yes
TNPO3_HUMAN [view interactions] Computational no yes