Features Interactions Isoform Disease Linear motifs Fingerprint Network All partners

MDM2_HUMAN

Evidence for PS localization

GO
G2C
SynGO
SynaptomeDB
HPA (protein expression in neurons)

Functions

E3 ubiquitin-protein ligase that mediates ubiquitination of p53/TP53, leading to its degradation by the proteasome (PubMed). Inhibits p53/TP53- and p73/TP73-mediated cell cycle arrest and apoptosis by binding its transcriptional activation domain. Also acts as a ubiquitin ligase E3 toward itself and ARRB1. Permits the nuclear export of p53/TP53. Promotes proteasome-dependent ubiquitin-independent degradation of retinoblastoma RB1 protein. Inhibits DAXX-mediated apoptosis by inducing its ubiquitination and degradation. Component of the TRIM28/KAP1-MDM2-p53/TP53 complex involved in stabilizing p53/TP53. Also a component of the TRIM28/KAP1-ERBB4-MDM2 complex which links growth factor and DNA damage response pathways. Mediates ubiquitination and subsequent proteasome degradation of DYRK2 in nucleus. Ubiquitinates IGF1R and SNAI1 and promotes them to proteasomal degradation (PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed). Ubiquitinates DCX, leading to DCX degradation and reduction of the dendritic spine density of olfactory bulb granule cells . Ubiquitinates DLG4, leading to proteasomal degradation of DLG4 which is required for AMPA receptor endocytosis . Negatively regulates NDUFS1, leading to decreased mitochondrial respiration, marked oxidative stress, and commitment to the mitochondrial pathway of apoptosis (PubMed). Binds NDUFS1 leading to its cytosolic retention rather than mitochondrial localization resulting in decreased supercomplex assembly (interactions between complex I and complex III), decreased complex I activity, ROS production, and apoptosis (PubMed). [View more on UniProt]

Protein features

Binary interactions with known binding regions

To display all evidence describing the interaction with a partner, click on the protein name left to the bars.

Network

Download full PS network for entry.

Isoforms

Disease-causing germline mutations

No data found.

Linear motifs

ELM instance Name Type Start End Partner
ELMI001069 DOC_USP7_MATH_1 DOC 147 151 -
ELMI001070 DOC_USP7_MATH_1 DOC 226 230 -
ELMI002274 DOC_USP7_MATH_1 DOC 397 401 -
ELMI003828 MOD_CK1_1 MOD 118 124 -
ELMI000953 MOD_PIKK_1 MOD 392 398 -
ELMI002276 MOD_PIKK_1 MOD 404 410 -
ELMI002550 MOD_PKB_1 MOD 161 169 -
ELMI002551 MOD_PKB_1 MOD 181 189 -
ELMI001069 DOC_USP7_MATH_1 DOC 147 151 -
ELMI001070 DOC_USP7_MATH_1 DOC 226 230 -
ELMI002274 DOC_USP7_MATH_1 DOC 397 401 -
ELMI003828 MOD_CK1_1 MOD 118 124 -
ELMI000953 MOD_PIKK_1 MOD 392 398 -
ELMI002276 MOD_PIKK_1 MOD 404 410 -
ELMI002550 MOD_PKB_1 MOD 161 169 -
ELMI002551 MOD_PKB_1 MOD 181 189 -

Fingerprint

Molecular function

Term Name % Distance from the top of the tree Annotated in MDM2_HUMAN
GO:0003723 RNA binding 40.0000 4 yes
GO:0043168 anion binding 28.4444 4 no
GO:0043169 cation binding 27.5556 4 yes
GO:0000166 nucleotide binding 27.1111 4 no
GO:0017076 purine nucleotide binding 27.1111 5 no
GO:0046872 metal ion binding 25.7778 5 yes
GO:0032555 purine ribonucleotide binding 25.3333 4 no
GO:0030554 adenyl nucleotide binding 24.4444 6 no
GO:0035639 purine ribonucleoside triphosphate binding 24.4444 4 no
GO:0032559 adenyl ribonucleotide binding 22.6667 5 no
GO:0005524 ATP binding 21.7778 5 no
GO:0044389 ubiquitin-like protein ligase binding 15.5556 4 yes
GO:0031625 ubiquitin protein ligase binding 15.1111 5 yes
GO:0016755 aminoacyltransferase activity 8.0000 4 yes
GO:0046914 transition metal ion binding 7.5556 6 yes
GO:0004842 ubiquitin-protein transferase activity 7.1111 4 yes
GO:0008270 zinc ion binding 5.7778 7 yes
GO:0019843 rRNA binding 5.7778 5 yes
GO:0061659 ubiquitin-like protein ligase activity 4.8889 4 yes
GO:0043130 ubiquitin binding 4.4444 4 yes
GO:0061630 ubiquitin protein ligase activity 4.4444 5 yes
GO:0097718 disordered domain specific binding 3.5556 4 yes
GO:0008097 5S rRNA binding 1.7778 6 yes
GO:0019789 SUMO transferase activity 1.7778 4 yes
GO:0019788 NEDD8 transferase activity 1.3333 4 yes
GO:0033612 receptor serine/threonine kinase binding 1.3333 4 yes
GO:0042975 peroxisome proliferator activated receptor binding 0.8889 4 yes
GO:0061663 NEDD8 ligase activity 0.8889 5 yes

Biological process

Term Name % Distance from top the of the tree Annotated in MDM2_HUMAN
GO:0048522 positive regulation of cellular process 59.1111 4 yes
GO:0060255 regulation of macromolecule metabolic process 57.3333 4 yes
GO:0080090 regulation of primary metabolic process 56.4444 4 yes
GO:0031323 regulation of cellular metabolic process 54.6667 4 yes
GO:0048523 negative regulation of cellular process 50.6667 4 yes
GO:0009889 regulation of biosynthetic process 48.4444 4 yes
GO:0031326 regulation of cellular biosynthetic process 48.0000 5 yes
GO:0010556 regulation of macromolecule biosynthetic process 47.5556 5 yes
GO:0010468 regulation of gene expression 44.8889 6 yes
GO:0010646 regulation of cell communication 44.8889 4 yes
GO:0009966 regulation of signal transduction 42.2222 4 yes
GO:0009893 positive regulation of metabolic process 41.7778 4 yes
GO:0010604 positive regulation of macromolecule metabolic process 40.4444 5 yes
GO:0019219 regulation of nucleobase-containing compound metabolic process 39.5556 5 yes
GO:0051246 regulation of protein metabolic process 38.2222 5 yes
GO:0031325 positive regulation of cellular metabolic process 36.4444 5 yes
GO:0009892 negative regulation of metabolic process 36.0000 4 yes
GO:0051252 regulation of RNA metabolic process 34.2222 5 yes
GO:0010605 negative regulation of macromolecule metabolic process 34.2222 5 yes
GO:0022607 cellular component assembly 32.8889 4 yes
GO:0051128 regulation of cellular component organization 32.4444 4 yes
GO:0048584 positive regulation of response to stimulus 32.4444 4 no
GO:0036211 protein modification process 32.0000 4 yes
GO:0043412 macromolecule modification 32.0000 4 yes
GO:2001141 regulation of RNA biosynthetic process 32.0000 6 yes
GO:0006355 regulation of DNA-templated transcription 32.0000 7 yes
GO:0009891 positive regulation of biosynthetic process 32.0000 5 yes
GO:0031328 positive regulation of cellular biosynthetic process 31.5556 6 yes
GO:1902531 regulation of intracellular signal transduction 31.5556 5 yes
GO:0010557 positive regulation of macromolecule biosynthetic process 31.1111 6 yes
GO:0031324 negative regulation of cellular metabolic process 30.6667 5 yes
GO:0023056 positive regulation of signaling 30.2222 4 no
GO:0042981 regulation of apoptotic process 29.7778 5 yes
GO:0043067 regulation of programmed cell death 29.7778 4 yes
GO:0010647 positive regulation of cell communication 29.7778 5 no
GO:0009967 positive regulation of signal transduction 28.8889 5 no
GO:0009059 macromolecule biosynthetic process 27.1111 4 no
GO:0009894 regulation of catabolic process 27.1111 4 yes
GO:0008104 protein localization 26.6667 4 yes
GO:0051247 positive regulation of protein metabolic process 26.2222 6 yes
GO:0043933 protein-containing complex organization 25.7778 4 yes
GO:0048585 negative regulation of response to stimulus 25.3333 4 yes
GO:0009890 negative regulation of biosynthetic process 25.3333 5 yes
GO:0031327 negative regulation of cellular biosynthetic process 24.8889 6 yes
GO:0010558 negative regulation of macromolecule biosynthetic process 24.8889 6 yes
GO:0006996 organelle organization 24.4444 4 no
GO:0023057 negative regulation of signaling 23.1111 4 yes
GO:0051049 regulation of transport 23.1111 4 yes
GO:0006357 regulation of transcription by RNA polymerase II 23.1111 8 yes
GO:0009968 negative regulation of signal transduction 23.1111 5 yes
GO:0010648 negative regulation of cell communication 23.1111 5 yes
GO:0090304 nucleic acid metabolic process 22.2222 4 no
GO:0031399 regulation of protein modification process 22.2222 6 no
GO:0051094 positive regulation of developmental process 21.7778 4 yes
GO:0060341 regulation of cellular localization 21.7778 4 yes
GO:0006796 phosphate-containing compound metabolic process 21.7778 4 no
GO:0045935 positive regulation of nucleobase-containing compound metabolic process 21.7778 5 no
GO:0032880 regulation of protein localization 21.3333 5 yes
GO:0071310 cellular response to organic substance 21.3333 4 yes
GO:1902533 positive regulation of intracellular signal transduction 21.3333 6 no
GO:0042127 regulation of cell population proliferation 20.8889 4 yes
GO:0045595 regulation of cell differentiation 20.4444 4 yes
GO:0045934 negative regulation of nucleobase-containing compound metabolic process 20.4444 5 yes
GO:1901566 organonitrogen compound biosynthetic process 20.4444 4 no
GO:0065003 protein-containing complex assembly 20.0000 5 yes
GO:0009057 macromolecule catabolic process 19.5556 4 yes
GO:0043066 negative regulation of apoptotic process 19.1111 6 yes
GO:0043069 negative regulation of programmed cell death 19.1111 5 yes
GO:0030162 regulation of proteolysis 18.6667 6 yes
GO:0051253 negative regulation of RNA metabolic process 18.2222 6 yes
GO:0051726 regulation of cell cycle 18.2222 4 yes
GO:0080134 regulation of response to stress 18.2222 4 yes
GO:0006508 proteolysis 18.2222 4 yes
GO:0051248 negative regulation of protein metabolic process 17.7778 6 yes
GO:1901701 cellular response to oxygen-containing compound 17.3333 4 yes
GO:0010628 positive regulation of gene expression 17.3333 7 yes
GO:0043687 post-translational protein modification 16.4444 5 yes
GO:1901565 organonitrogen compound catabolic process 16.4444 4 yes
GO:0010243 response to organonitrogen compound 16.4444 4 yes
GO:0019941 modification-dependent protein catabolic process 16.0000 6 yes
GO:0043632 modification-dependent macromolecule catabolic process 16.0000 5 yes
GO:0045892 negative regulation of DNA-templated transcription 16.0000 8 yes
GO:0051603 proteolysis involved in protein catabolic process 16.0000 5 yes
GO:1902679 negative regulation of RNA biosynthetic process 16.0000 7 yes
GO:0070647 protein modification by small protein conjugation or removal 15.5556 6 yes
GO:0045597 positive regulation of cell differentiation 14.6667 5 yes
GO:0032446 protein modification by small protein conjugation 14.2222 7 yes
GO:0042176 regulation of protein catabolic process 14.2222 5 yes
GO:0006511 ubiquitin-dependent protein catabolic process 14.2222 7 yes
GO:0030163 protein catabolic process 13.7778 4 yes
GO:0051050 positive regulation of transport 13.7778 4 yes
GO:0010629 negative regulation of gene expression 13.7778 7 yes
GO:0033365 protein localization to organelle 13.3333 5 yes
GO:0033993 response to lipid 13.3333 4 yes
GO:1902532 negative regulation of intracellular signal transduction 13.3333 6 yes
GO:0008284 positive regulation of cell population proliferation 13.3333 5 yes
GO:1901699 cellular response to nitrogen compound 12.8889 4 yes
GO:1903050 regulation of proteolysis involved in protein catabolic process 12.8889 7 yes
GO:1903829 positive regulation of protein localization 12.8889 5 yes
GO:0000122 negative regulation of transcription by RNA polymerase II 12.8889 9 yes
GO:0071417 cellular response to organonitrogen compound 12.4444 4 yes
GO:2001233 regulation of apoptotic signaling pathway 12.4444 5 yes
GO:0009896 positive regulation of catabolic process 12.4444 5 yes
GO:0014070 response to organic cyclic compound 12.4444 4 yes
GO:0010564 regulation of cell cycle process 12.0000 5 yes
GO:0016567 protein ubiquitination 11.5556 8 yes
GO:0018193 peptidyl-amino acid modification 11.5556 5 yes
GO:2000058 regulation of ubiquitin-dependent protein catabolic process 11.5556 5 yes
GO:0006915 apoptotic process 11.5556 4 yes
GO:0006974 DNA damage response 11.5556 4 yes
GO:0010498 proteasomal protein catabolic process 11.5556 5 yes
GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process 11.1111 6 yes
GO:0045862 positive regulation of proteolysis 11.1111 7 yes
GO:0051129 negative regulation of cellular component organization 11.1111 5 yes
GO:0070201 regulation of establishment of protein localization 11.1111 6 yes
GO:0080135 regulation of cellular response to stress 11.1111 4 yes
GO:0030334 regulation of cell migration 10.2222 5 yes
GO:2000145 regulation of cell motility 10.2222 4 yes
GO:0031344 regulation of cell projection organization 9.7778 5 yes
GO:0044057 regulation of system process 9.7778 4 yes
GO:0045732 positive regulation of protein catabolic process 9.3333 6 yes
GO:0061136 regulation of proteasomal protein catabolic process 9.3333 6 yes
GO:0120035 regulation of plasma membrane bounded cell projection organization 9.3333 6 yes
GO:0051223 regulation of protein transport 8.8889 5 yes
GO:0071407 cellular response to organic cyclic compound 8.8889 5 yes
GO:1901796 regulation of signal transduction by p53 class mediator 8.8889 6 yes
GO:0007346 regulation of mitotic cell cycle 8.8889 5 yes
GO:0010038 response to metal ion 8.8889 4 yes
GO:0071363 cellular response to growth factor stimulus 8.4444 4 yes
GO:0030335 positive regulation of cell migration 8.0000 6 yes
GO:0032434 regulation of proteasomal ubiquitin-dependent protein catabolic process 8.0000 6 yes
GO:0040017 positive regulation of locomotion 8.0000 4 yes
GO:0045787 positive regulation of cell cycle 8.0000 5 yes
GO:0097435 supramolecular fiber organization 8.0000 4 yes
GO:2000147 positive regulation of cell motility 8.0000 5 yes
GO:2001242 regulation of intrinsic apoptotic signaling pathway 8.0000 6 yes
GO:0045861 negative regulation of proteolysis 7.5556 7 yes
GO:1903052 positive regulation of proteolysis involved in protein catabolic process 7.5556 8 yes
GO:0010975 regulation of neuron projection development 7.5556 7 yes
GO:0032870 cellular response to hormone stimulus 7.1111 4 yes
GO:0036293 response to decreased oxygen levels 7.1111 4 yes
GO:1901800 positive regulation of proteasomal protein catabolic process 7.1111 7 yes
GO:1901987 regulation of cell cycle phase transition 7.1111 6 yes
GO:1904951 positive regulation of establishment of protein localization 7.1111 6 yes
GO:2001234 negative regulation of apoptotic signaling pathway 7.1111 6 yes
GO:0062197 cellular response to chemical stress 6.6667 4 yes
GO:1901990 regulation of mitotic cell cycle phase transition 6.6667 6 yes
GO:2000060 positive regulation of ubiquitin-dependent protein catabolic process 6.6667 6 yes
GO:0009416 response to light stimulus 6.6667 4 yes
GO:0032386 regulation of intracellular transport 6.2222 5 yes
GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process 6.2222 7 yes
GO:0034599 cellular response to oxidative stress 6.2222 4 yes
GO:0045786 negative regulation of cell cycle 6.2222 5 yes
GO:0090068 positive regulation of cell cycle process 6.2222 6 yes
GO:0097305 response to alcohol 6.2222 4 yes
GO:0043434 response to peptide hormone 5.7778 4 yes
GO:1903522 regulation of blood circulation 5.7778 5 yes
GO:0034504 protein localization to nucleus 5.3333 6 yes
GO:0032388 positive regulation of intracellular transport 4.8889 5 yes
GO:0048545 response to steroid hormone 4.8889 4 yes
GO:0051222 positive regulation of protein transport 4.8889 5 yes
GO:0000302 response to reactive oxygen species 4.8889 4 yes
GO:0036294 cellular response to decreased oxygen levels 4.4444 5 yes
GO:0071375 cellular response to peptide hormone stimulus 4.4444 5 yes
GO:0071453 cellular response to oxygen levels 4.4444 4 yes
GO:1902806 regulation of cell cycle G1/S phase transition 4.4444 7 yes
GO:0000209 protein polyubiquitination 4.4444 9 yes
GO:0008016 regulation of heart contraction 4.4444 6 yes
GO:0009411 response to UV 4.4444 5 yes
GO:0033157 regulation of intracellular protein transport 4.0000 6 yes
GO:0042542 response to hydrogen peroxide 4.0000 4 yes
GO:0043279 response to alkaloid 4.0000 5 yes
GO:0045930 negative regulation of mitotic cell cycle 4.0000 6 yes
GO:0045931 positive regulation of mitotic cell cycle 4.0000 6 yes
GO:0046822 regulation of nucleocytoplasmic transport 4.0000 6 yes
GO:0097306 cellular response to alcohol 4.0000 5 yes
GO:1902253 regulation of intrinsic apoptotic signaling pathway by p53 class mediator 4.0000 7 yes
GO:2000045 regulation of G1/S transition of mitotic cell cycle 4.0000 7 yes
GO:2001243 negative regulation of intrinsic apoptotic signaling pathway 4.0000 7 yes
GO:0010948 negative regulation of cell cycle process 4.0000 6 yes
GO:0018205 peptidyl-lysine modification 3.5556 6 yes
GO:0034614 cellular response to reactive oxygen species 3.5556 5 yes
GO:0042770 signal transduction in response to DNA damage 3.5556 4 yes
GO:0071456 cellular response to hypoxia 3.5556 4 yes
GO:1990000 amyloid fibril formation 3.5556 4 yes
GO:0046824 positive regulation of nucleocytoplasmic transport 3.1111 6 yes
GO:0048660 regulation of smooth muscle cell proliferation 3.1111 5 yes
GO:0070301 cellular response to hydrogen peroxide 3.1111 5 yes
GO:0072331 signal transduction by p53 class mediator 3.1111 4 yes
GO:0090316 positive regulation of intracellular protein transport 3.1111 6 yes
GO:1901988 negative regulation of cell cycle phase transition 3.1111 7 yes
GO:1901989 positive regulation of cell cycle phase transition 3.1111 7 yes
GO:1901991 negative regulation of mitotic cell cycle phase transition 3.1111 7 yes
GO:0000075 cell cycle checkpoint signaling 3.1111 4 yes
GO:0007093 mitotic cell cycle checkpoint signaling 3.1111 4 yes
GO:0016925 protein sumoylation 2.6667 7 yes
GO:0031345 negative regulation of cell projection organization 2.6667 6 yes
GO:0031570 DNA integrity checkpoint signaling 2.6667 5 yes
GO:0034644 cellular response to UV 2.6667 6 yes
GO:0042220 response to cocaine 2.6667 4 yes
GO:0043516 regulation of DNA damage response, signal transduction by p53 class mediator 2.6667 5 yes
GO:0044773 mitotic DNA damage checkpoint signaling 2.6667 6 yes
GO:0044774 mitotic DNA integrity checkpoint signaling 2.6667 5 yes
GO:0048661 positive regulation of smooth muscle cell proliferation 2.6667 6 yes
GO:0051147 regulation of muscle cell differentiation 2.6667 5 yes
GO:0051149 positive regulation of muscle cell differentiation 2.6667 6 yes
GO:0071478 cellular response to radiation 2.6667 4 yes
GO:0071482 cellular response to light stimulus 2.6667 5 yes
GO:1901992 positive regulation of mitotic cell cycle phase transition 2.6667 7 yes
GO:0000077 DNA damage checkpoint signaling 2.6667 5 yes
GO:0010212 response to ionizing radiation 2.6667 4 yes
GO:0030330 DNA damage response, signal transduction by p53 class mediator 2.2222 5 yes
GO:0031571 mitotic G1 DNA damage checkpoint signaling 2.2222 6 yes
GO:0031648 protein destabilization 2.2222 4 yes
GO:0033273 response to vitamin 2.2222 4 yes
GO:0044819 mitotic G1/S transition checkpoint signaling 2.2222 5 yes
GO:0046825 regulation of protein export from nucleus 2.2222 7 yes
GO:0051865 protein autoubiquitination 2.2222 9 yes
GO:1902807 negative regulation of cell cycle G1/S phase transition 2.2222 8 yes
GO:1902808 positive regulation of cell cycle G1/S phase transition 2.2222 8 yes
GO:2000134 negative regulation of G1/S transition of mitotic cell cycle 2.2222 8 yes
GO:0010039 response to iron ion 2.2222 5 yes
GO:0010977 negative regulation of neuron projection development 2.2222 7 yes
GO:0014911 positive regulation of smooth muscle cell migration 1.7778 7 yes
GO:0046827 positive regulation of protein export from nucleus 1.7778 7 yes
GO:0070613 regulation of protein processing 1.7778 7 yes
GO:0071312 cellular response to alkaloid 1.7778 5 yes
GO:1900087 positive regulation of G1/S transition of mitotic cell cycle 1.7778 8 yes
GO:1901797 negative regulation of signal transduction by p53 class mediator 1.7778 7 yes
GO:1903317 regulation of protein maturation 1.7778 6 yes
GO:0010332 response to gamma radiation 1.7778 5 yes
GO:0014910 regulation of smooth muscle cell migration 1.7778 6 yes
GO:0031670 cellular response to nutrient 1.3333 4 yes
GO:0043518 negative regulation of DNA damage response, signal transduction by p53 class mediator 1.3333 6 yes
GO:0043627 response to estrogen 1.3333 4 yes
GO:0045472 response to ether 1.3333 4 yes
GO:0071236 cellular response to antibiotic 1.3333 4 yes
GO:0071479 cellular response to ionizing radiation 1.3333 5 yes
GO:0071480 cellular response to gamma radiation 1.3333 6 yes
GO:0072132 mesenchyme morphogenesis 1.3333 4 yes
GO:0072716 response to actinomycin D 1.3333 4 yes
GO:0072717 cellular response to actinomycin D 1.3333 5 yes
GO:1902254 negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator 1.3333 8 yes
GO:1904705 regulation of vascular associated smooth muscle cell proliferation 1.3333 6 yes
GO:1904707 positive regulation of vascular associated smooth muscle cell proliferation 1.3333 7 yes
GO:0003181 atrioventricular valve morphogenesis 1.3333 4 yes
GO:0003203 endocardial cushion morphogenesis 1.3333 5 yes
GO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest 1.3333 6 yes
GO:0032026 response to magnesium ion 0.8889 5 yes
GO:0071295 cellular response to vitamin 0.8889 5 yes
GO:0071301 cellular response to vitamin B1 0.8889 5 yes
GO:0071391 cellular response to estrogen stimulus 0.8889 5 yes
GO:0071494 cellular response to UV-C 0.8889 7 yes
GO:1903318 negative regulation of protein maturation 0.8889 7 yes
GO:1904404 response to formaldehyde 0.8889 4 yes
GO:1904752 regulation of vascular associated smooth muscle cell migration 0.8889 7 yes
GO:1904754 positive regulation of vascular associated smooth muscle cell migration 0.8889 8 yes
GO:1990785 response to water-immersion restraint stress 0.8889 4 yes
GO:0003281 ventricular septum development 0.8889 4 yes
GO:0003283 atrial septum development 0.8889 4 yes
GO:0007089 traversing start control point of mitotic cell cycle 0.8889 9 yes
GO:0010225 response to UV-C 0.8889 6 yes
GO:0010266 response to vitamin B1 0.8889 5 yes
GO:0010955 negative regulation of protein processing 0.8889 8 yes

Disease

No data found.

All partners

Uniprot ID Details Highest evidence Localizing into PSD HPA (protein expression in neurons)
KPYM_HUMAN [view interactions] Low throughput no yes
RS2_HUMAN [view entry] [view interactions] Low throughput yes yes
ATRX_HUMAN [view entry] [view interactions] Low throughput yes yes
CD276_HUMAN [view interactions] Low throughput no yes
PSMD1_HUMAN [view entry] [view interactions] Low throughput yes yes
RBM10_HUMAN [view interactions] Low throughput no yes
CTNB1_HUMAN [view entry] [view interactions] Low throughput yes yes
CDN1A_HUMAN [view interactions] Low throughput no no
MTBP_HUMAN [view interactions] Low throughput no no
DYR_HUMAN [view interactions] Low throughput no yes
UB2D1_HUMAN [view interactions] Low throughput no yes
LATS2_HUMAN [view interactions] Low throughput no yes
DPOE1_HUMAN [view interactions] Low throughput no no
HIF1A_HUMAN [view interactions] Low throughput no no
NDKB_HUMAN [view entry] [view interactions] Low throughput yes yes
UBE2K_HUMAN [view interactions] Low throughput no yes
DNJB1_HUMAN [view entry] [view interactions] Low throughput yes yes
PPIB_HUMAN [view entry] [view interactions] Low throughput yes yes
PER2_HUMAN [view interactions] Low throughput no yes
NAT10_HUMAN [view interactions] Low throughput no yes
CCND1_HUMAN [view interactions] Low throughput no yes
RNF12_HUMAN [view interactions] Low throughput no yes
VHL_HUMAN [view entry] [view interactions] Low throughput yes yes
IEX1_HUMAN [view interactions] Low throughput no yes
CTBP1_HUMAN [view entry] [view interactions] Low throughput yes yes
FHL2_HUMAN [view interactions] Low throughput no yes
CTBP2_HUMAN [view interactions] Low throughput no no
RL23A_HUMAN [view entry] [view interactions] Low throughput yes yes
UBE2A_HUMAN [view interactions] Low throughput no no
SUZ12_HUMAN [view interactions] Low throughput no no
KAT5_HUMAN [view interactions] Low throughput no yes
EZH2_HUMAN [view interactions] Low throughput no no
EID1_HUMAN [view interactions] Low throughput no yes
EED_HUMAN [view interactions] Low throughput no yes
KAT2B_HUMAN [view interactions] Low throughput no yes
RIR1_HUMAN [view entry] [view interactions] Low throughput yes yes
EP300_HUMAN [view interactions] Low throughput no yes
RL4_HUMAN [view entry] [view interactions] Low throughput yes yes
ABL1_HUMAN [view entry] [view interactions] Low throughput yes yes
PBIP1_HUMAN [view entry] [view interactions] Low throughput yes no
CCNG1_HUMAN [view interactions] Low throughput no yes
SP1_HUMAN [view interactions] Low throughput no yes
TS101_HUMAN [view entry] [view interactions] Low throughput yes yes
SHRPN_HUMAN [view entry] [view interactions] Low throughput yes yes
FOXO4_HUMAN [view interactions] Low throughput no no
CCAR1_HUMAN [view interactions] Low throughput no yes
UBP26_HUMAN [view interactions] Low throughput no no
RFFL_HUMAN [view interactions] Low throughput no yes
FKB1A_HUMAN [view interactions] Low throughput no yes
PSD10_HUMAN [view entry] [view interactions] Low throughput yes yes
TNR16_HUMAN [view entry] [view interactions] Low throughput yes no
CSN5_HUMAN [view interactions] Low throughput no yes
SMG7_HUMAN [view interactions] Low throughput no no
CADH1_HUMAN [view entry] [view interactions] Low throughput yes no
RL1D1_HUMAN [view interactions] Low throughput no yes
IFIX_HUMAN [view interactions] Low throughput no no
SIR1_HUMAN [view interactions] Low throughput no yes
BANP_HUMAN [view interactions] Low throughput no yes
SIR7_HUMAN [view interactions] Low throughput no yes
DDX17_HUMAN [view entry] [view interactions] Low throughput yes yes
IMA7_HUMAN [view interactions] Low throughput no yes
E2F1_HUMAN [view interactions] Low throughput no yes
MSI2H_HUMAN [view interactions] Low throughput no yes
TIF1B_HUMAN [view interactions] Low throughput no yes
PHLB3_HUMAN [view interactions] Low throughput no yes
GATA3_HUMAN [view interactions] Low throughput no no
H2B2E_HUMAN [view interactions] Low throughput no yes
RD23A_HUMAN [view interactions] Low throughput no yes
GCR_HUMAN [view entry] [view interactions] Low throughput yes yes
UBC9_HUMAN [view entry] [view interactions] Low throughput yes yes
EHMT1_HUMAN [view interactions] Low throughput no yes
SUV91_HUMAN [view interactions] Low throughput no no
H31T_HUMAN [view interactions] Low throughput no yes
TAF1_HUMAN [view interactions] Low throughput no yes
SIVA_HUMAN [view interactions] Low throughput no no
MTA1_HUMAN [view interactions] Low throughput no yes
ZN363_HUMAN [view interactions] Low throughput no yes
G3BP2_HUMAN [view entry] [view interactions] Low throughput yes yes
PSMD2_HUMAN [view entry] [view interactions] Low throughput yes yes
PK1IP_HUMAN [view interactions] Low throughput no yes
ZN668_HUMAN [view interactions] Low throughput no yes
CRTC2_HUMAN [view interactions] Low throughput no yes
PCNA_HUMAN [view interactions] Low throughput no no
CRTC3_HUMAN [view interactions] Low throughput no no
UBP10_HUMAN [view interactions] Low throughput no yes
VEGFA_HUMAN [view entry] [view interactions] Low throughput yes yes
PSMD4_HUMAN [view interactions] Low throughput no yes
UBP48_HUMAN [view interactions] Low throughput no yes
PRS6A_HUMAN [view entry] [view interactions] Low throughput yes yes
QORX_HUMAN [view interactions] Low throughput no yes
PRS8_HUMAN [view interactions] Low throughput no yes
HUWE1_HUMAN [view interactions] Low throughput no yes
BCAR1_HUMAN [view interactions] Low throughput no yes
PSA7_HUMAN [view interactions] Low throughput no yes
1433Z_HUMAN [view entry] [view interactions] Low throughput yes yes
RUNX3_HUMAN [view interactions] Low throughput no no
PAK4_HUMAN [view interactions] Low throughput no yes
TERT_HUMAN [view interactions] Low throughput no no
MPIP3_HUMAN [view interactions] Low throughput no yes
APEX1_HUMAN [view interactions] Low throughput no yes
XBP1_HUMAN [view interactions] Low throughput no no
UIMC1_HUMAN [view interactions] Low throughput no no
RL22_HUMAN [view entry] [view interactions] Low throughput yes no
CBP_HUMAN [view interactions] Low throughput no yes
DLG2_HUMAN [view entry] [view interactions] Low throughput yes yes
SOX4_HUMAN [view interactions] Low throughput no yes
BTK_HUMAN [view interactions] Low throughput no no
UBE4B_HUMAN [view interactions] Low throughput no yes
TBRG1_HUMAN [view interactions] Low throughput no no
MARH7_HUMAN [view interactions] Low throughput no yes
BI2L1_HUMAN [view interactions] Low throughput no yes
P53_HUMAN [view interactions] Low throughput no no
ERBB3_HUMAN [view interactions] Low throughput no yes
BAG6_HUMAN [view entry] [view interactions] Low throughput yes yes
PA2G4_HUMAN [view interactions] Low throughput no yes
HEXI1_HUMAN [view interactions] Low throughput no yes
MDM4_HUMAN [view interactions] Low throughput no yes
CDK9_HUMAN [view interactions] Low throughput no yes
ARRB2_HUMAN [view entry] [view interactions] Low throughput yes no
DYRK2_HUMAN [view interactions] Low throughput no yes
RBP2_HUMAN [view interactions] Low throughput no yes
ARRB1_HUMAN [view entry] [view interactions] Low throughput yes yes
ATF3_HUMAN [view interactions] Low throughput no yes
ESR1_HUMAN [view interactions] Low throughput no no
HS90A_HUMAN [view entry] [view interactions] Low throughput yes yes
RS7_HUMAN [view entry] [view interactions] Low throughput yes yes
HSP74_HUMAN [view entry] [view interactions] Low throughput yes yes
PP2AA_HUMAN [view entry] [view interactions] Low throughput yes yes
RL11_HUMAN [view entry] [view interactions] Low throughput yes yes
LAMP2_HUMAN [view interactions] Low throughput no yes
UBP12_HUMAN [view interactions] Low throughput no yes
RL23_HUMAN [view entry] [view interactions] Low throughput yes yes
TRI13_HUMAN [view interactions] Low throughput no no
REST_HUMAN [view interactions] Low throughput no yes
FKBP3_HUMAN [view interactions] Low throughput no yes
XRCC6_HUMAN [view interactions] Low throughput no yes
U119A_HUMAN [view interactions] Low throughput no no
RYBP_HUMAN [view interactions] Low throughput no no
FOXO1_HUMAN [view interactions] Low throughput no yes
ROA1_HUMAN [view entry] [view interactions] Low throughput yes yes
ATF4_HUMAN [view interactions] Low throughput no no
FOXO3_HUMAN [view interactions] Low throughput no yes
HMGA2_HUMAN [view interactions] Low throughput no yes
UCHL1_HUMAN [view entry] [view interactions] Low throughput yes yes
MYL6B_HUMAN [view entry] [view interactions] Low throughput yes no
RL26_HUMAN [view entry] [view interactions] Low throughput yes yes
UBP42_HUMAN [view interactions] Low throughput no no
ALBU_HUMAN [view interactions] Low throughput no no
RS27A_HUMAN [view entry] [view interactions] Low throughput yes yes
COP1_HUMAN [view interactions] Low throughput no no
TRI59_HUMAN [view interactions] Low throughput no no
SMUF1_HUMAN [view interactions] Low throughput no yes
LYRIC_HUMAN [view entry] [view interactions] Low throughput yes yes
NOTC4_HUMAN [view interactions] Low throughput no no
IRS1_HUMAN [view entry] [view interactions] Low throughput yes yes
PDLI7_HUMAN [view entry] [view interactions] Low throughput yes no
GYS2_HUMAN [view interactions] Low throughput no no
SENP3_HUMAN [view interactions] Low throughput no yes
WRN_HUMAN [view interactions] Low throughput no yes
PDE4D_HUMAN [view entry] [view interactions] Low throughput yes yes
DYR1A_HUMAN [view interactions] Low throughput no yes
NOTC1_HUMAN [view entry] [view interactions] Low throughput yes yes
HDAC2_HUMAN [view interactions] Low throughput no yes
PAX3_HUMAN [view interactions] Low throughput no no
FBX22_HUMAN [view interactions] Low throughput no no
TRI27_HUMAN [view interactions] Low throughput no yes
CAC1C_HUMAN [view entry] [view interactions] Low throughput yes no
SENP2_HUMAN [view interactions] Low throughput no yes
NDUS1_HUMAN [view entry] [view interactions] Low throughput yes no
RS14_HUMAN [view entry] [view interactions] Low throughput yes yes
EGLN3_HUMAN [view interactions] Low throughput no no
RASF5_HUMAN [view interactions] Low throughput no yes
PTPA_HUMAN [view interactions] Low throughput no yes
TRI67_HUMAN [view interactions] Low throughput no no
HIPK2_HUMAN [view interactions] Low throughput no yes
TTF1_HUMAN [view interactions] Low throughput no yes
HDAC3_HUMAN [view interactions] Low throughput no yes
UBP7_HUMAN [view interactions] Low throughput no yes
PSMA8_HUMAN [view interactions] Low throughput no no
UT2_HUMAN [view interactions] Low throughput no no
DAXX_HUMAN [view interactions] Low throughput no yes
RASF3_HUMAN [view interactions] Low throughput no yes
FUS_HUMAN [view entry] [view interactions] Low throughput yes yes
MDM2_HUMAN [view entry] [view interactions] Low throughput yes yes
UBE2B_HUMAN [view interactions] Low throughput no no
ZN398_HUMAN [view interactions] Low throughput no no
BHE40_HUMAN [view interactions] Low throughput no yes
LATS1_HUMAN [view entry] [view interactions] Low throughput yes yes
PIAS1_HUMAN [view entry] [view interactions] Low throughput yes yes
UBB_HUMAN [view entry] [view interactions] Low throughput yes yes
LNX1_HUMAN [view entry] [view interactions] Low throughput yes yes
PSME3_HUMAN [view interactions] Low throughput no yes
P63_HUMAN [view interactions] Low throughput no no
RASF1_HUMAN [view interactions] Low throughput no yes
HERC2_HUMAN [view interactions] Low throughput no yes
UBC_HUMAN [view entry] [view interactions] Low throughput yes yes
NBN_HUMAN [view interactions] Low throughput no yes
KPCB_HUMAN [view entry] [view interactions] Low throughput yes yes
SNAI1_HUMAN [view interactions] Low throughput no yes
PLCE1_HUMAN [view interactions] Low throughput no yes
GORAB_HUMAN [view interactions] Low throughput no yes
PRKN_HUMAN [view entry] [view interactions] Low throughput yes yes
CUL1_HUMAN [view interactions] Low throughput no yes
SCN3B_HUMAN [view interactions] Low throughput no no
FBW1A_HUMAN [view interactions] Low throughput no yes
GSK3B_HUMAN [view entry] [view interactions] Low throughput yes yes
K1C10_HUMAN [view interactions] Low throughput no no
FBW1B_HUMAN [view interactions] Low throughput no yes
ESR2_HUMAN [view interactions] Low throughput no no
IREB2_HUMAN [view interactions] Low throughput no no
AATF_HUMAN [view interactions] Low throughput no yes
SRBP1_HUMAN [view interactions] Low throughput no yes
KC1A_HUMAN [view interactions] Low throughput no yes
BUB1B_HUMAN [view interactions] Low throughput no no
FOXP3_HUMAN [view interactions] Low throughput no no
KC1D_HUMAN [view entry] [view interactions] Low throughput yes yes
POLH_HUMAN [view interactions] Low throughput no yes
PARP6_HUMAN [view interactions] Low throughput no yes
RB_HUMAN [view interactions] Low throughput no yes
CK5P3_HUMAN [view entry] [view interactions] Low throughput yes yes
RS27L_HUMAN [view entry] [view interactions] Low throughput yes no
IRF2_HUMAN [view interactions] Low throughput no yes
ACE2_HUMAN [view interactions] Low throughput no no
RS27_HUMAN [view entry] [view interactions] Low throughput yes no
RS25_HUMAN [view entry] [view interactions] Low throughput yes yes
UBP14_HUMAN [view entry] [view interactions] Low throughput yes yes
GNL3L_HUMAN [view interactions] Low throughput no yes
ELAV1_HUMAN [view entry] [view interactions] Low throughput yes yes
DRD2_HUMAN [view entry] [view interactions] Low throughput yes no
GNL3_HUMAN [view interactions] Low throughput no yes
TCTP_HUMAN [view entry] [view interactions] Low throughput yes yes
DRD3_HUMAN [view entry] [view interactions] Low throughput yes no
ANGI_HUMAN [view interactions] Low throughput no no
2A5G_HUMAN [view interactions] Low throughput no yes
RHOA_HUMAN [view entry] [view interactions] Low throughput yes yes
HIPK1_HUMAN [view interactions] Low throughput no no
PDCD5_HUMAN [view interactions] Low throughput no yes
NR0B2_HUMAN [view interactions] Low throughput no no
CARF_HUMAN [view interactions] Low throughput no yes
OTUB1_HUMAN [view interactions] Low throughput no yes
WWOX_HUMAN [view interactions] Low throughput no yes
ARI2_HUMAN [view interactions] Low throughput no no
NUMB_HUMAN [view entry] [view interactions] Low throughput yes yes
RIR2B_HUMAN [view interactions] Low throughput no yes
RL40_HUMAN [view entry] [view interactions] Low throughput yes yes
CUL4B_HUMAN [view interactions] Low throughput no yes
NUCL_HUMAN [view interactions] Low throughput no yes
DHRS2_HUMAN [view interactions] Low throughput no no
RS3_HUMAN [view entry] [view interactions] Low throughput yes yes
ITCH_HUMAN [view interactions] Low throughput no yes
PML_HUMAN [view interactions] Low throughput no yes
1433S_HUMAN [view entry] [view interactions] Low throughput yes yes
TBP_HUMAN [view interactions] Low throughput no yes
MED1_HUMAN [view interactions] Low throughput no no
ERBB4_HUMAN [view entry] [view interactions] Low throughput yes yes
CHK2_HUMAN [view interactions] Low throughput no yes
HNF4A_HUMAN [view interactions] Low throughput no no
NPM_HUMAN [view entry] [view interactions] Low throughput yes yes
MDC1_HUMAN [view interactions] Low throughput no yes
UBP2_HUMAN [view interactions] Low throughput no yes
PP1A_HUMAN [view entry] [view interactions] Low throughput yes yes
PLK1_HUMAN [view interactions] Low throughput no yes
RING2_HUMAN [view interactions] Low throughput no yes
1433T_HUMAN [view entry] [view interactions] Low throughput yes yes
RS6_HUMAN [view entry] [view interactions] Low throughput yes yes
DLG4_HUMAN [view entry] [view interactions] Low throughput yes yes
EGR1_HUMAN [view interactions] Low throughput no yes
EF1A1_HUMAN [view entry] [view interactions] Low throughput yes yes
PAK6_HUMAN [view entry] [view interactions] Low throughput yes yes
RS20_HUMAN [view entry] [view interactions] Low throughput yes yes
IRF1_HUMAN [view interactions] Low throughput no yes
S10A1_HUMAN [view interactions] Low throughput no yes
TERA_HUMAN [view entry] [view interactions] Low throughput yes yes
S100B_HUMAN [view entry] [view interactions] Low throughput yes yes
CENPX_HUMAN [view interactions] Low throughput no no
S10A4_HUMAN [view entry] [view interactions] Low throughput yes no
GA45A_HUMAN [view interactions] Low throughput no no
S10A6_HUMAN [view interactions] Low throughput no yes
RABL6_HUMAN [view interactions] Low throughput no yes
S10A2_HUMAN [view interactions] Low throughput no no
NECD_HUMAN [view interactions] Low throughput no no
ARBK1_HUMAN [view entry] [view interactions] Low throughput yes yes
MELK_HUMAN [view interactions] Low throughput no yes
RL5_HUMAN [view entry] [view interactions] Low throughput yes yes
RS26_HUMAN [view entry] [view interactions] Low throughput yes yes
JMY_HUMAN [view interactions] Low throughput no yes
RL37_HUMAN [view entry] [view interactions] Low throughput yes no
RS15_HUMAN [view entry] [view interactions] Low throughput yes yes
OVOL2_HUMAN [view interactions] Low throughput no no
RASF6_HUMAN [view interactions] Low throughput no yes
AGGF1_HUMAN [view interactions] Low throughput no no
TAB1_HUMAN [view interactions] Low throughput no yes
STA5A_HUMAN [view interactions] Low throughput no no
RL6_HUMAN [view entry] [view interactions] Low throughput yes yes
CBL_HUMAN [view interactions] Low throughput no yes
AURKA_HUMAN [view entry] [view interactions] Low throughput yes no
STAT3_HUMAN [view entry] [view interactions] Low throughput yes yes
XIAP_HUMAN [view interactions] Low throughput no yes
ACHA4_HUMAN [view entry] [view interactions] Low throughput yes no
PPM1D_HUMAN [view interactions] Low throughput no no
NOC2L_HUMAN [view interactions] Low throughput no yes
RNC_HUMAN [view entry] [view interactions] Low throughput yes no
ANDR_HUMAN [view interactions] Low throughput no no
JAK1_HUMAN [view interactions] Low throughput no yes
DPP4_HUMAN [view interactions] Low throughput no no
HNRPK_HUMAN [view entry] [view interactions] Low throughput yes yes
NEDD4_HUMAN [view entry] [view interactions] Low throughput yes yes
DUS26_HUMAN [view interactions] Low throughput no yes
CDN2A_HUMAN [view interactions] Low throughput no yes
XPC_HUMAN [view interactions] Low throughput no yes
ZWINT_HUMAN [view entry] [view interactions] Low throughput yes no
KS6B1_HUMAN [view entry] [view interactions] Low throughput yes yes
PGAM1_HUMAN [view entry] [view interactions] Low throughput yes yes
AKT1_HUMAN [view entry] [view interactions] Low throughput yes yes
PGAM2_HUMAN [view entry] [view interactions] Low throughput yes no
BABA2_HUMAN [view interactions] Low throughput no yes
PSA6_HUMAN [view interactions] Low throughput no yes
ANC2_HUMAN [view interactions] Low throughput no no
PSB6_HUMAN [view entry] [view interactions] Low throughput yes yes
NLK_HUMAN [view interactions] Low throughput no yes
AURKB_HUMAN [view interactions] Low throughput no yes
PSA3_HUMAN [view interactions] Low throughput no no
SNAI2_HUMAN [view interactions] Low throughput no yes
UBE4A_HUMAN [view entry] [view interactions] Low throughput yes yes
TYY1_HUMAN [view interactions] Low throughput no yes
RBM38_HUMAN [view interactions] Low throughput no yes
STK11_HUMAN [view interactions] Low throughput no yes
RBBP6_HUMAN [view interactions] Low throughput no yes
FHIT_HUMAN [view interactions] Low throughput no yes
YBOX1_HUMAN [view interactions] Low throughput no yes
XPO1_HUMAN [view entry] [view interactions] Low throughput yes yes
KLOT_HUMAN [view interactions] Low throughput no no
SUMO1_HUMAN [view entry] [view interactions] Low throughput yes yes
SHAN1_HUMAN [view entry] [view interactions] Low throughput yes yes
RFWD3_HUMAN [view interactions] Low throughput no yes
PAQR3_HUMAN [view interactions] Low throughput no no
P73_HUMAN [view interactions] Low throughput no no
DHX9_HUMAN [view interactions] Low throughput no yes
HDAC1_HUMAN [view interactions] Low throughput no no
PARP1_HUMAN [view entry] [view interactions] Low throughput yes yes
UB2D2_HUMAN [view interactions] Low throughput no yes
IF4G2_HUMAN [view entry] [view interactions] Low throughput yes yes
PIM1_HUMAN [view interactions] Low throughput no yes
MAGC2_HUMAN [view interactions] Low throughput no no
PIM2_HUMAN [view interactions] Low throughput no no
CCDC3_HUMAN [view interactions] Low throughput no no
PIM3_HUMAN [view interactions] Low throughput no no
GTF2I_HUMAN [view interactions] Low throughput no yes
PR15A_HUMAN [view interactions] Low throughput no yes
KS6A1_HUMAN [view entry] [view interactions] Low throughput yes yes
KS6A3_HUMAN [view entry] [view interactions] Low throughput yes yes
PTC1_HUMAN [view entry] [view interactions] Low throughput yes yes
T2EB_HUMAN [view interactions] Low throughput no yes
TF65_HUMAN [view entry] [view interactions] Low throughput yes yes
FAK1_HUMAN [view entry] [view interactions] Low throughput yes yes
UB2D3_HUMAN [view interactions] Low throughput no yes
PBX1_HUMAN [view interactions] Low throughput no yes
UB2L3_HUMAN [view interactions] Low throughput no yes
UB2E2_HUMAN [view interactions] Low throughput no yes
UB2E3_HUMAN [view interactions] Low throughput no yes
SMCA2_HUMAN [view interactions] Low throughput no yes
SETD7_HUMAN [view interactions] Low throughput no yes
UBP15_HUMAN [view entry] [view interactions] Low throughput yes yes
IMA5_HUMAN [view entry] [view interactions] Low throughput yes yes
HEY1_HUMAN [view interactions] Low throughput no yes
CASP2_HUMAN [view interactions] Low throughput no yes
CASP3_HUMAN [view entry] [view interactions] Low throughput yes yes
SIR6_HUMAN [view interactions] Low throughput no yes
T22D3_HUMAN [view interactions] Low throughput no yes
FSBP_HUMAN [view interactions] Low throughput no yes
TELT_HUMAN [view interactions] Low throughput no no
UBE2H_HUMAN [view interactions] Low throughput no yes
NR1I2_HUMAN [view interactions] Low throughput no no
ADRB2_HUMAN [view entry] [view interactions] Low throughput yes no
UBE3A_HUMAN [view entry] [view interactions] Low throughput yes yes
RANG_HUMAN [view interactions] Low throughput no no
HSP7C_HUMAN [view entry] [view interactions] Low throughput yes yes
DAPK3_HUMAN [view interactions] Low throughput no yes
ATM_HUMAN [view interactions] Low throughput no yes
CDK2_HUMAN [view interactions] Low throughput no yes
MAPK2_HUMAN [view interactions] Low throughput no yes
IGF1R_HUMAN [view entry] [view interactions] Low throughput yes yes
SIR2_HUMAN [view entry] [view interactions] Low throughput yes yes
SIR3_HUMAN [view interactions] Low throughput no yes
TF_HUMAN [view interactions] Low throughput no no
CSK21_HUMAN [view entry] [view interactions] Low throughput yes yes
MAGA2_HUMAN [view interactions] Low throughput no no
CSK2B_HUMAN [view entry] [view interactions] Low throughput yes yes
ENPL_HUMAN [view entry] [view interactions] Low throughput yes yes
ZN420_HUMAN [view interactions] Low throughput no yes
CSK22_HUMAN [view entry] [view interactions] Low throughput yes no
ELF4_HUMAN [view interactions] Low throughput no no
PP1RA_HUMAN [view interactions] Low throughput no yes
SRC_HUMAN [view entry] [view interactions] Low throughput yes no
RS5_HUMAN [view entry] [view interactions] Low throughput yes yes
UBC12_HUMAN [view entry] [view interactions] Low throughput yes yes
APOB_HUMAN [view interactions] Low throughput no no
PPARG_HUMAN [view interactions] Low throughput no yes
VDR_HUMAN [view interactions] Low throughput no no
DAPK1_HUMAN [view entry] [view interactions] Low throughput yes yes
CEBPB_HUMAN [view interactions] Low throughput no no
ABL2_HUMAN [view entry] [view interactions] Low throughput yes yes
FBX31_HUMAN [view entry] [view interactions] Low throughput yes yes
HCK_HUMAN [view entry] [view interactions] Low throughput yes no
TFP11_HUMAN [view interactions] Low throughput no no
RARA_HUMAN [view interactions] Low throughput no no
DDX24_HUMAN [view interactions] Low throughput no yes
EPS15_HUMAN [view entry] [view interactions] High throughput yes yes
HMGB2_HUMAN [view interactions] High throughput no yes
CD20_HUMAN [view interactions] High throughput no no
ACM3_HUMAN [view entry] [view interactions] High throughput yes yes
XRCC5_HUMAN [view interactions] High throughput no yes
PDIA3_HUMAN [view entry] [view interactions] High throughput yes yes
BCD1_HUMAN [view interactions] High throughput no yes
RL3_HUMAN [view entry] [view interactions] High throughput yes yes
RAB8A_HUMAN [view entry] [view interactions] High throughput yes no
MEA1_HUMAN [view interactions] High throughput no no
RL9_HUMAN [view entry] [view interactions] High throughput yes yes
RS23_HUMAN [view entry] [view interactions] High throughput yes yes
STX1A_HUMAN [view entry] [view interactions] High throughput yes yes
RS10_HUMAN [view entry] [view interactions] High throughput yes yes
RUVB2_HUMAN [view interactions] High throughput no yes
RS19_HUMAN [view entry] [view interactions] High throughput yes no
SMCA4_HUMAN [view interactions] High throughput no yes
TM87A_HUMAN [view interactions] High throughput no yes
SMCE1_HUMAN [view interactions] High throughput no yes
PRC2C_HUMAN [view interactions] High throughput no yes
RS3A_HUMAN [view entry] [view interactions] High throughput yes yes
SRS11_HUMAN [view interactions] High throughput no yes
SMC3_HUMAN [view entry] [view interactions] High throughput yes yes
RS9_HUMAN [view entry] [view interactions] High throughput yes yes
TPR_HUMAN [view interactions] High throughput no yes
MTAP2_HUMAN [view entry] [view interactions] High throughput yes yes
MEP50_HUMAN [view interactions] High throughput no yes
TBB5_HUMAN [view interactions] High throughput no yes
HNRPF_HUMAN [view interactions] High throughput no yes
SEC63_HUMAN [view interactions] High throughput no yes
HNRH1_HUMAN [view entry] [view interactions] High throughput yes yes
RT33_HUMAN [view interactions] High throughput no no
NSD2_HUMAN [view interactions] High throughput no yes
U520_HUMAN [view interactions] High throughput no yes
ZN326_HUMAN [view interactions] High throughput no yes
GRWD1_HUMAN [view interactions] High throughput no no
NP1L1_HUMAN [view entry] [view interactions] High throughput yes yes
TM10C_HUMAN [view interactions] High throughput no yes
TCPB_HUMAN [view entry] [view interactions] High throughput yes yes
TCPD_HUMAN [view entry] [view interactions] High throughput yes yes
TCPE_HUMAN [view entry] [view interactions] High throughput yes yes
PRS7_HUMAN [view interactions] High throughput no yes
TCPA_HUMAN [view entry] [view interactions] High throughput yes yes
ECHA_HUMAN [view entry] [view interactions] High throughput yes yes
1433B_HUMAN [view entry] [view interactions] High throughput yes yes
STK38_HUMAN [view entry] [view interactions] High throughput yes yes
ST38L_HUMAN [view entry] [view interactions] High throughput yes yes
NACAM_HUMAN [view interactions] High throughput no no
PI42C_HUMAN [view interactions] High throughput no yes
RO52_HUMAN [view interactions] High throughput no yes
TR150_HUMAN [view interactions] High throughput no yes
FOS_HUMAN [view interactions] High throughput no yes
AKAP5_HUMAN [view entry] [view interactions] High throughput yes yes
WDTC1_HUMAN [view interactions] High throughput no yes
CLPB_HUMAN [view interactions] High throughput no yes
XAGE1_HUMAN [view interactions] High throughput no no
ZN550_HUMAN [view interactions] High throughput no no
YAF2_HUMAN [view interactions] High throughput no yes
PDGFB_HUMAN [view interactions] High throughput no yes
BMAL2_HUMAN [view interactions] High throughput no yes
RS11_HUMAN [view entry] [view interactions] High throughput yes yes
RL15_HUMAN [view entry] [view interactions] High throughput yes no
TSYL6_HUMAN [view interactions] High throughput no no
H2B1J_HUMAN [view interactions] High throughput no yes
ZN764_HUMAN [view interactions] High throughput no no
MAK16_HUMAN [view interactions] High throughput no yes
ZN274_HUMAN [view interactions] High throughput no yes
SSF1_HUMAN [view interactions] High throughput no yes
RL37A_HUMAN [view entry] [view interactions] High throughput yes yes
TRI25_HUMAN [view interactions] High throughput no yes
PRS4_HUMAN [view entry] [view interactions] High throughput yes yes
PRS10_HUMAN [view interactions] High throughput no yes
FGF11_HUMAN [view interactions] High throughput no no
TRI46_HUMAN [view interactions] High throughput no no
K1671_HUMAN [view interactions] High throughput no yes
LZTS2_HUMAN [view interactions] High throughput no no
RN115_HUMAN [view interactions] High throughput no yes
MAGD2_HUMAN [view interactions] High throughput no yes
VCIP1_HUMAN [view entry] [view interactions] High throughput yes no
TRI32_HUMAN [view entry] [view interactions] High throughput yes yes
TRI47_HUMAN [view entry] [view interactions] High throughput yes yes
LMO7_HUMAN [view entry] [view interactions] High throughput yes yes
C560_HUMAN [view interactions] High throughput no no
SRBS2_HUMAN [view entry] [view interactions] High throughput yes no
SETB1_HUMAN [view interactions] High throughput no yes
RIDA_HUMAN [view interactions] High throughput no yes
DNJB4_HUMAN [view entry] [view interactions] High throughput yes yes
SHPK_HUMAN [view interactions] High throughput no no
ANR17_HUMAN [view interactions] High throughput no yes
NOP53_HUMAN [view interactions] High throughput no yes
YYAP1_HUMAN [view interactions] High throughput no yes
SESN2_HUMAN [view interactions] High throughput no no
DET1_HUMAN [view interactions] High throughput no no
BRD1_HUMAN [view interactions] High throughput no yes
RAD50_HUMAN [view interactions] High throughput no yes
MRE11_HUMAN [view interactions] High throughput no yes
CUL4A_HUMAN [view interactions] High throughput no no
DTL_HUMAN [view interactions] High throughput no no
KC1E_HUMAN [view entry] [view interactions] High throughput yes yes
RIGI_HUMAN [view interactions] High throughput no yes
NOG2_HUMAN [view interactions] High throughput no yes
SAP30_HUMAN [view interactions] High throughput no yes
EHBP1_HUMAN [view interactions] High throughput no yes
SRP14_HUMAN [view interactions] High throughput no no
H2AB1_HUMAN [view interactions] High throughput no no
ZN200_HUMAN [view interactions] High throughput no yes
ERCC6_HUMAN [view interactions] High throughput no no
TP4A3_HUMAN [view interactions] High throughput no no
ERCC8_HUMAN [view interactions] High throughput no no
REXO4_HUMAN [view interactions] High throughput no yes
DDB1_HUMAN [view interactions] High throughput no yes
PIAS4_HUMAN [view interactions] High throughput no yes
TRM6_HUMAN [view interactions] High throughput no yes
ZN707_HUMAN [view interactions] High throughput no yes
RL18_HUMAN [view entry] [view interactions] High throughput yes yes
TBB2A_HUMAN [view entry] [view interactions] High throughput yes yes
TSSK6_HUMAN [view interactions] High throughput no no
G3P_HUMAN [view entry] [view interactions] High throughput yes yes
NDNF_HUMAN [view interactions] High throughput no no
GELS_HUMAN [view entry] [view interactions] High throughput yes no
IQCF2_HUMAN [view interactions] High throughput no no
ZN562_HUMAN [view interactions] High throughput no yes
H2BWT_HUMAN [view interactions] High throughput no no
TYMOS_HUMAN [view interactions] High throughput no no
RL10_HUMAN [view entry] [view interactions] High throughput yes yes
RAB15_HUMAN [view entry] [view interactions] High throughput yes yes
H1FNT_HUMAN [view interactions] High throughput no yes
TIM50_HUMAN [view entry] [view interactions] High throughput yes yes
ZN784_HUMAN [view interactions] High throughput no no
ZIM2_HUMAN [view interactions] High throughput no no
UBP51_HUMAN [view interactions] High throughput no yes
HUS1B_HUMAN [view interactions] High throughput no no
ZN777_HUMAN [view interactions] High throughput no yes
H2B3B_HUMAN [view interactions] High throughput no yes
RL31_HUMAN [view entry] [view interactions] High throughput yes yes
H2AZ_HUMAN [view interactions] High throughput no yes
RL36L_HUMAN [view interactions] High throughput no no
HMGN1_HUMAN [view interactions] High throughput no yes
G3PT_HUMAN [view interactions] High throughput no no
CDN2B_HUMAN [view interactions] High throughput no no
TBA1C_HUMAN [view interactions] High throughput no yes
DCD_HUMAN [view interactions] High throughput no no
TBB1_HUMAN [view interactions] High throughput no yes
K1C14_HUMAN [view interactions] High throughput no no
YTDC1_HUMAN [view interactions] High throughput no yes
PHB2_HUMAN [view entry] [view interactions] High throughput yes yes
ADAS_HUMAN [view interactions] High throughput no yes
A16A1_HUMAN [view entry] [view interactions] High throughput yes no
DDX5_HUMAN [view entry] [view interactions] High throughput yes yes
HERC5_HUMAN [view interactions] High throughput no yes
ODP2_HUMAN [view entry] [view interactions] High throughput yes yes
EDC4_HUMAN [view interactions] High throughput no yes
E2AK1_HUMAN [view interactions] High throughput no yes
ESYT1_HUMAN [view entry] [view interactions] High throughput yes yes
GBB1_HUMAN [view entry] [view interactions] High throughput yes yes
UB2G2_HUMAN [view interactions] High throughput no yes
HMHA1_HUMAN [view interactions] High throughput no no
UBE2U_HUMAN [view interactions] High throughput no no
HNRPM_HUMAN [view entry] [view interactions] High throughput yes yes
UBE2Z_HUMAN [view interactions] High throughput no yes
HNRPU_HUMAN [view interactions] High throughput no yes
DMB_HUMAN [view interactions] High throughput no no
HORN_HUMAN [view interactions] High throughput no no
MYD88_HUMAN [view interactions] High throughput no yes
HS90B_HUMAN [view entry] [view interactions] High throughput yes yes
SYIC_HUMAN [view interactions] High throughput no yes
WT1_HUMAN [view interactions] High throughput no no
IF16_HUMAN [view interactions] High throughput no no
KBL_HUMAN [view interactions] High throughput no yes
IF2B3_HUMAN [view interactions] High throughput no no
POTE1_HUMAN [view interactions] High throughput no no
ILF3_HUMAN [view interactions] High throughput no yes
MKRN3_HUMAN [view interactions] High throughput no yes
SYK_HUMAN [view interactions] High throughput no yes
TRI23_HUMAN [view interactions] High throughput no yes
CCAR2_HUMAN [view interactions] High throughput no yes
TRIM4_HUMAN [view interactions] High throughput no yes
NEK9_HUMAN [view interactions] High throughput no yes
UBE2N_HUMAN [view entry] [view interactions] High throughput yes yes
TRIM9_HUMAN [view entry] [view interactions] High throughput yes no
ODO1_HUMAN [view entry] [view interactions] High throughput yes yes
TRAF5_HUMAN [view interactions] High throughput no yes
OGDHL_HUMAN [view entry] [view interactions] High throughput yes yes
RN126_HUMAN [view interactions] High throughput no yes
SYRC_HUMAN [view interactions] High throughput no yes
PHF7_HUMAN [view interactions] High throughput no no
CTIP_HUMAN [view interactions] High throughput no no
RNF10_HUMAN [view entry] [view interactions] High throughput yes yes
RECQ1_HUMAN [view interactions] High throughput no yes
RNF8_HUMAN [view interactions] High throughput no yes
SF3B1_HUMAN [view interactions] High throughput no yes
UB2D4_HUMAN [view interactions] High throughput no yes
SFPQ_HUMAN [view entry] [view interactions] High throughput yes yes
UB2E1_HUMAN [view interactions] High throughput no yes
TOP1_HUMAN [view interactions] High throughput no yes
UB2J2_HUMAN [view interactions] High throughput no no
JUN_HUMAN [view interactions] High throughput no yes
ZN318_HUMAN [view interactions] High throughput no yes
UBE2O_HUMAN [view interactions] High throughput no yes
RYR2_HUMAN [view entry] [view interactions] High throughput yes yes
UB2Q1_HUMAN [view interactions] High throughput no no
JUND_HUMAN [view interactions] High throughput no yes
UB2Q2_HUMAN [view interactions] High throughput no no
EZRI_HUMAN [view entry] [view interactions] High throughput yes no
UB2R1_HUMAN [view interactions] High throughput no yes
ACACA_HUMAN [view entry] [view interactions] High throughput yes yes
UB2R2_HUMAN [view interactions] High throughput no no
PFD6_HUMAN [view interactions] High throughput no yes
PTBP1_HUMAN [view interactions] High throughput no no
UBE2S_HUMAN [view interactions] High throughput no no
M4K4_HUMAN [view interactions] High throughput no yes
IYD1_HUMAN [view interactions] High throughput no no
CSTN1_HUMAN [view entry] [view interactions] High throughput yes yes
ACTB_HUMAN [view entry] [view interactions] High throughput yes no
BAIP2_HUMAN [view entry] [view interactions] High throughput yes yes
HNRPD_HUMAN [view entry] [view interactions] High throughput yes yes
SRP19_HUMAN [view interactions] High throughput no yes
U2AF2_HUMAN [view interactions] High throughput no yes
EF1G_HUMAN [view entry] [view interactions] High throughput yes yes
FUBP1_HUMAN [view interactions] High throughput no yes
TFR1_HUMAN [view entry] [view interactions] High throughput yes yes
ERIC3_HUMAN [view interactions] High throughput no no
EF2_HUMAN [view entry] [view interactions] High throughput yes yes
A4_HUMAN [view entry] [view interactions] High throughput yes yes
K22E_HUMAN [view interactions] High throughput no no
WIPI4_HUMAN [view interactions] High throughput no no
EIF3B_HUMAN [view interactions] High throughput no yes
NOLC1_HUMAN [view interactions] High throughput no yes
SYMC_HUMAN [view interactions] High throughput no yes
SND1_HUMAN [view entry] [view interactions] High throughput yes yes
DDX42_HUMAN [view interactions] High throughput no yes
RGRF1_HUMAN [view entry] [view interactions] High throughput yes yes
DCAF8_HUMAN [view interactions] High throughput no yes
RRP1_HUMAN [view interactions] High throughput no yes
F1711_HUMAN [view entry] [view interactions] High throughput yes yes
USO1_HUMAN [view entry] [view interactions] High throughput yes yes
PDS5A_HUMAN [view interactions] High throughput no yes
NUDT9_HUMAN [view interactions] High throughput no yes
U5S1_HUMAN [view interactions] High throughput no yes
RL36A_HUMAN [view entry] [view interactions] High throughput yes yes
RCN2_HUMAN [view interactions] High throughput no yes
EXOS6_HUMAN [view interactions] High throughput no no
UBF1_HUMAN [view interactions] High throughput no yes
CLUS_HUMAN [view entry] [view interactions] High throughput yes yes
IPO7_HUMAN [view entry] [view interactions] High throughput yes yes
PRPK_HUMAN [view interactions] High throughput no yes
ZBTB1_HUMAN [view interactions] High throughput no no
SF3B3_HUMAN [view interactions] High throughput no yes
NPIB3_HUMAN [view interactions] High throughput no yes
PTPRD_HUMAN [view entry] [view interactions] High throughput yes no
RL10A_HUMAN [view entry] [view interactions] High throughput yes yes
MLP3A_HUMAN [view entry] [view interactions] High throughput yes yes
SREK1_HUMAN [view interactions] High throughput no yes
DIRA3_HUMAN [view interactions] High throughput no yes
PRDM2_HUMAN [view interactions] High throughput no yes
GSTP1_HUMAN [view entry] [view interactions] High throughput yes no
SURF2_HUMAN [view interactions] High throughput no yes
RESF1_HUMAN [view interactions] High throughput no yes
DAAM2_HUMAN [view entry] [view interactions] High throughput yes yes
RFPL2_HUMAN [view interactions] High throughput no no
CMS1_HUMAN [view interactions] High throughput no yes
RL27A_HUMAN [view entry] [view interactions] High throughput yes yes
PPARD_HUMAN [view interactions] High throughput no yes
KIF5A_HUMAN [view entry] [view interactions] High throughput yes yes
RL22L_HUMAN [view interactions] High throughput no no
ARHG6_HUMAN [view interactions] High throughput no no
IER2_HUMAN [view interactions] High throughput no no
SET_HUMAN [view interactions] High throughput no yes
FEZ1_HUMAN [view interactions] High throughput no no
GBRA2_HUMAN [view entry] [view interactions] High throughput yes no
OGA_HUMAN [view interactions] High throughput no yes
TSNAX_HUMAN [view interactions] High throughput no yes
PHOP1_HUMAN [view interactions] High throughput no no
GLIS2_HUMAN [view interactions] High throughput no no
TBCA_HUMAN [view interactions] High throughput no yes
MYC_HUMAN [view interactions] High throughput no yes
ZN766_HUMAN [view interactions] High throughput no yes
CWC25_HUMAN [view interactions] High throughput no yes
NDUAC_HUMAN [view entry] [view interactions] High throughput yes yes
NFM_HUMAN [view entry] [view interactions] High throughput yes yes
AT2A2_HUMAN [view entry] [view interactions] High throughput yes yes
NUCKS_HUMAN [view interactions] High throughput no yes
BRNP1_HUMAN [view interactions] High throughput no yes
ZN133_HUMAN [view interactions] High throughput no yes
MYDGF_HUMAN [view interactions] High throughput no yes
PRP6_HUMAN [view interactions] High throughput no yes
HMGB1_HUMAN [view interactions] High throughput no yes
CALX_HUMAN [view entry] [view interactions] High throughput yes yes