ADRB2_HUMAN
Evidence for PS localization
Functions
Beta-adrenergic receptors mediate the catecholamine-induced activation of adenylate cyclase through the action of G proteins. The beta-2-adrenergic receptor binds epinephrine with an approximately 30-fold greater affinity than it does norepinephrine. [View more on UniProt]
Protein features
Binary interactions with known binding regions
To display all evidence describing the interaction with a partner, click on the protein name left to the bars.
Network
Isoforms
No data found.
Disease-causing germline mutations
No data found.
Linear motifs
| ELM instance | Name | Type | Start | End | Partner |
|---|---|---|---|---|---|
| ELMI001598 | LIG_PDZ_Class_1 | LIG | 408 | 413 | - |
| ELMI001598 | LIG_PDZ_Class_1 | LIG | 408 | 413 | - |
Fingerprint
Molecular function
| Term | Name | % | Distance from the top of the tree | Annotated in ADRB2_HUMAN |
|---|---|---|---|---|
| GO:0000166 | nucleotide binding | 27.5862 | 4 | no |
| GO:0017076 | purine nucleotide binding | 26.4368 | 5 | no |
| GO:0043169 | cation binding | 24.7126 | 4 | yes |
| GO:0043168 | anion binding | 24.1379 | 4 | no |
| GO:0003723 | RNA binding | 22.9885 | 4 | no |
| GO:0032555 | purine ribonucleotide binding | 22.4138 | 4 | no |
| GO:0046872 | metal ion binding | 22.4138 | 5 | no |
| GO:0035639 | purine ribonucleoside triphosphate binding | 21.8391 | 4 | no |
| GO:0042803 | protein homodimerization activity | 8.6207 | 4 | yes |
| GO:0099106 | ion channel regulator activity | 5.1724 | 4 | yes |
| GO:0004930 | G protein-coupled receptor activity | 4.5977 | 4 | yes |
| GO:0008179 | adenylate cyclase binding | 3.4483 | 4 | yes |
| GO:0008227 | G protein-coupled amine receptor activity | 2.8736 | 5 | yes |
| GO:0015459 | potassium channel regulator activity | 2.8736 | 5 | yes |
| GO:0004935 | adrenergic receptor activity | 1.7241 | 6 | yes |
| GO:0004939 | beta-adrenergic receptor activity | 1.7241 | 7 | yes |
| GO:0051380 | norepinephrine binding | 1.7241 | 4 | yes |
| GO:0004941 | beta2-adrenergic receptor activity | 1.1494 | 8 | yes |
Biological process
| Term | Name | % | Distance from top the of the tree | Annotated in ADRB2_HUMAN |
|---|---|---|---|---|
| GO:0048523 | negative regulation of cellular process | 45.9770 | 4 | yes |
| GO:0031323 | regulation of cellular metabolic process | 44.8276 | 4 | yes |
| GO:0048522 | positive regulation of cellular process | 43.1034 | 4 | yes |
| GO:0060255 | regulation of macromolecule metabolic process | 42.5287 | 4 | yes |
| GO:0080090 | regulation of primary metabolic process | 39.6552 | 4 | yes |
| GO:0010646 | regulation of cell communication | 36.7816 | 4 | yes |
| GO:0009966 | regulation of signal transduction | 33.9080 | 4 | yes |
| GO:0009893 | positive regulation of metabolic process | 33.3333 | 4 | yes |
| GO:0009889 | regulation of biosynthetic process | 32.7586 | 4 | yes |
| GO:0031326 | regulation of cellular biosynthetic process | 32.1839 | 5 | yes |
| GO:0010556 | regulation of macromolecule biosynthetic process | 31.0345 | 5 | yes |
| GO:0010604 | positive regulation of macromolecule metabolic process | 29.8851 | 5 | yes |
| GO:0051246 | regulation of protein metabolic process | 29.8851 | 5 | yes |
| GO:0010468 | regulation of gene expression | 29.3103 | 6 | yes |
| GO:0051049 | regulation of transport | 29.3103 | 4 | yes |
| GO:0006996 | organelle organization | 28.7356 | 4 | no |
| GO:0031325 | positive regulation of cellular metabolic process | 28.7356 | 5 | yes |
| GO:0008104 | protein localization | 28.1609 | 4 | no |
| GO:0022607 | cellular component assembly | 25.8621 | 4 | yes |
| GO:0051128 | regulation of cellular component organization | 25.8621 | 4 | yes |
| GO:0009892 | negative regulation of metabolic process | 25.2874 | 4 | no |
| GO:0071702 | organic substance transport | 24.1379 | 4 | no |
| GO:0031324 | negative regulation of cellular metabolic process | 23.5632 | 5 | no |
| GO:0071705 | nitrogen compound transport | 22.9885 | 4 | no |
| GO:0048585 | negative regulation of response to stimulus | 22.9885 | 4 | yes |
| GO:1902531 | regulation of intracellular signal transduction | 22.4138 | 5 | yes |
| GO:0010605 | negative regulation of macromolecule metabolic process | 22.4138 | 5 | no |
| GO:0048584 | positive regulation of response to stimulus | 22.4138 | 4 | yes |
| GO:0019219 | regulation of nucleobase-containing compound metabolic process | 21.8391 | 5 | yes |
| GO:0051247 | positive regulation of protein metabolic process | 21.2644 | 6 | yes |
| GO:0010648 | negative regulation of cell communication | 21.2644 | 5 | yes |
| GO:0023057 | negative regulation of signaling | 21.2644 | 4 | yes |
| GO:0042981 | regulation of apoptotic process | 20.6897 | 5 | no |
| GO:0043067 | regulation of programmed cell death | 20.6897 | 4 | no |
| GO:0009891 | positive regulation of biosynthetic process | 20.1149 | 5 | yes |
| GO:0009968 | negative regulation of signal transduction | 20.1149 | 5 | yes |
| GO:0051252 | regulation of RNA metabolic process | 19.5402 | 5 | yes |
| GO:0023056 | positive regulation of signaling | 19.5402 | 4 | yes |
| GO:0031328 | positive regulation of cellular biosynthetic process | 19.5402 | 6 | yes |
| GO:0031399 | regulation of protein modification process | 19.5402 | 6 | yes |
| GO:0010557 | positive regulation of macromolecule biosynthetic process | 18.9655 | 6 | yes |
| GO:0010647 | positive regulation of cell communication | 18.9655 | 5 | yes |
| GO:0071310 | cellular response to organic substance | 18.3908 | 4 | yes |
| GO:2001141 | regulation of RNA biosynthetic process | 18.3908 | 6 | yes |
| GO:0006355 | regulation of DNA-templated transcription | 18.3908 | 7 | yes |
| GO:0009894 | regulation of catabolic process | 18.3908 | 4 | yes |
| GO:0009967 | positive regulation of signal transduction | 17.8161 | 5 | yes |
| GO:0019220 | regulation of phosphate metabolic process | 17.8161 | 6 | yes |
| GO:0043933 | protein-containing complex organization | 17.8161 | 4 | yes |
| GO:0051174 | regulation of phosphorus metabolic process | 17.8161 | 5 | yes |
| GO:0043085 | positive regulation of catalytic activity | 16.0920 | 4 | yes |
| GO:0042325 | regulation of phosphorylation | 15.5172 | 7 | yes |
| GO:0043269 | regulation of monoatomic ion transport | 15.5172 | 5 | yes |
| GO:0001932 | regulation of protein phosphorylation | 14.9425 | 7 | yes |
| GO:0051050 | positive regulation of transport | 14.9425 | 4 | yes |
| GO:0065003 | protein-containing complex assembly | 14.3678 | 5 | yes |
| GO:1901362 | organic cyclic compound biosynthetic process | 14.3678 | 4 | yes |
| GO:0033043 | regulation of organelle organization | 14.3678 | 5 | yes |
| GO:0034762 | regulation of transmembrane transport | 14.3678 | 4 | yes |
| GO:0098657 | import into cell | 13.7931 | 4 | yes |
| GO:0051240 | positive regulation of multicellular organismal process | 13.7931 | 4 | yes |
| GO:0031401 | positive regulation of protein modification process | 13.2184 | 7 | yes |
| GO:0034765 | regulation of monoatomic ion transmembrane transport | 13.2184 | 5 | yes |
| GO:0051130 | positive regulation of cellular component organization | 13.2184 | 5 | yes |
| GO:0051338 | regulation of transferase activity | 12.6437 | 4 | yes |
| GO:0090304 | nucleic acid metabolic process | 12.6437 | 4 | yes |
| GO:1902533 | positive regulation of intracellular signal transduction | 12.6437 | 6 | yes |
| GO:0010959 | regulation of metal ion transport | 12.6437 | 6 | yes |
| GO:0010243 | response to organonitrogen compound | 12.0690 | 4 | yes |
| GO:0010562 | positive regulation of phosphorus metabolic process | 12.0690 | 6 | yes |
| GO:0034654 | nucleobase-containing compound biosynthetic process | 12.0690 | 4 | yes |
| GO:0043549 | regulation of kinase activity | 12.0690 | 5 | yes |
| GO:0045937 | positive regulation of phosphate metabolic process | 12.0690 | 7 | yes |
| GO:0006357 | regulation of transcription by RNA polymerase II | 11.4943 | 8 | yes |
| GO:0045859 | regulation of protein kinase activity | 11.4943 | 6 | yes |
| GO:0051241 | negative regulation of multicellular organismal process | 11.4943 | 4 | yes |
| GO:0001934 | positive regulation of protein phosphorylation | 10.9195 | 8 | yes |
| GO:0009059 | macromolecule biosynthetic process | 10.9195 | 4 | yes |
| GO:0031329 | regulation of cellular catabolic process | 10.9195 | 5 | yes |
| GO:0042327 | positive regulation of phosphorylation | 10.9195 | 8 | yes |
| GO:0051094 | positive regulation of developmental process | 10.9195 | 4 | yes |
| GO:1901701 | cellular response to oxygen-containing compound | 10.3448 | 4 | yes |
| GO:0006898 | receptor-mediated endocytosis | 10.3448 | 4 | yes |
| GO:0010506 | regulation of autophagy | 10.3448 | 6 | yes |
| GO:0045935 | positive regulation of nucleobase-containing compound metabolic process | 10.3448 | 5 | yes |
| GO:0099177 | regulation of trans-synaptic signaling | 9.7701 | 4 | yes |
| GO:0044057 | regulation of system process | 9.7701 | 4 | yes |
| GO:0050804 | modulation of chemical synaptic transmission | 9.7701 | 5 | yes |
| GO:0051347 | positive regulation of transferase activity | 9.1954 | 5 | yes |
| GO:0051254 | positive regulation of RNA metabolic process | 8.6207 | 6 | yes |
| GO:2000026 | regulation of multicellular organismal development | 8.6207 | 4 | yes |
| GO:0009896 | positive regulation of catabolic process | 8.6207 | 5 | yes |
| GO:0016070 | RNA metabolic process | 8.6207 | 5 | yes |
| GO:0033674 | positive regulation of kinase activity | 8.6207 | 6 | yes |
| GO:0043408 | regulation of MAPK cascade | 8.6207 | 6 | yes |
| GO:0045860 | positive regulation of protein kinase activity | 8.6207 | 7 | yes |
| GO:0071900 | regulation of protein serine/threonine kinase activity | 8.0460 | 7 | yes |
| GO:1902680 | positive regulation of RNA biosynthetic process | 8.0460 | 7 | yes |
| GO:0045893 | positive regulation of DNA-templated transcription | 8.0460 | 8 | yes |
| GO:0007188 | adenylate cyclase-modulating G protein-coupled receptor signaling pathway | 7.4713 | 4 | yes |
| GO:0022898 | regulation of transmembrane transporter activity | 7.4713 | 4 | yes |
| GO:0090257 | regulation of muscle system process | 6.8966 | 5 | yes |
| GO:1901699 | cellular response to nitrogen compound | 6.8966 | 4 | yes |
| GO:0010638 | positive regulation of organelle organization | 6.8966 | 6 | yes |
| GO:0016241 | regulation of macroautophagy | 6.8966 | 7 | yes |
| GO:0032412 | regulation of monoatomic ion transmembrane transporter activity | 6.8966 | 5 | yes |
| GO:0043410 | positive regulation of MAPK cascade | 6.8966 | 7 | yes |
| GO:0008277 | regulation of G protein-coupled receptor signaling pathway | 6.3218 | 5 | yes |
| GO:0043270 | positive regulation of monoatomic ion transport | 6.3218 | 5 | yes |
| GO:0051093 | negative regulation of developmental process | 6.3218 | 4 | yes |
| GO:0071417 | cellular response to organonitrogen compound | 5.7471 | 4 | yes |
| GO:0071902 | positive regulation of protein serine/threonine kinase activity | 5.7471 | 8 | yes |
| GO:0141187 | nucleic acid biosynthetic process | 5.7471 | 5 | yes |
| GO:0006937 | regulation of muscle contraction | 5.7471 | 6 | yes |
| GO:0007034 | vacuolar transport | 5.7471 | 4 | yes |
| GO:0034764 | positive regulation of transmembrane transport | 5.7471 | 5 | yes |
| GO:0034767 | positive regulation of monoatomic ion transmembrane transport | 5.7471 | 6 | yes |
| GO:0045944 | positive regulation of transcription by RNA polymerase II | 5.7471 | 9 | yes |
| GO:0007041 | lysosomal transport | 5.1724 | 5 | yes |
| GO:0045744 | negative regulation of G protein-coupled receptor signaling pathway | 5.1724 | 6 | yes |
| GO:0003018 | vascular process in circulatory system | 4.5977 | 4 | yes |
| GO:0045926 | negative regulation of growth | 4.5977 | 4 | yes |
| GO:0002028 | regulation of sodium ion transport | 4.0230 | 7 | yes |
| GO:0032411 | positive regulation of transporter activity | 4.0230 | 4 | yes |
| GO:0032414 | positive regulation of ion transmembrane transporter activity | 4.0230 | 5 | yes |
| GO:0032774 | RNA biosynthetic process | 4.0230 | 5 | yes |
| GO:0001894 | tissue homeostasis | 3.4483 | 4 | yes |
| GO:0007189 | adenylate cyclase-activating G protein-coupled receptor signaling pathway | 3.4483 | 5 | yes |
| GO:0031331 | positive regulation of cellular catabolic process | 3.4483 | 6 | yes |
| GO:0048638 | regulation of developmental growth | 3.4483 | 4 | yes |
| GO:0051339 | regulation of lyase activity | 2.8736 | 4 | yes |
| GO:0002029 | desensitization of G protein-coupled receptor signaling pathway | 2.8736 | 7 | yes |
| GO:0006351 | DNA-templated transcription | 2.8736 | 6 | yes |
| GO:0006366 | transcription by RNA polymerase II | 2.8736 | 7 | yes |
| GO:0006936 | muscle contraction | 2.8736 | 4 | yes |
| GO:0010508 | positive regulation of autophagy | 2.8736 | 7 | yes |
| GO:0016239 | positive regulation of macroautophagy | 2.8736 | 8 | yes |
| GO:0022401 | negative adaptation of signaling pathway | 2.8736 | 6 | yes |
| GO:0023058 | adaptation of signaling pathway | 2.8736 | 5 | yes |
| GO:0031279 | regulation of cyclase activity | 2.8736 | 4 | yes |
| GO:0043244 | regulation of protein-containing complex disassembly | 2.8736 | 5 | yes |
| GO:0043393 | regulation of protein binding | 2.8736 | 4 | yes |
| GO:0045761 | regulation of adenylate cyclase activity | 2.8736 | 5 | yes |
| GO:0097746 | blood vessel diameter maintenance | 2.2989 | 5 | yes |
| GO:0099601 | regulation of neurotransmitter receptor activity | 2.2989 | 4 | yes |
| GO:2000479 | regulation of cAMP-dependent protein kinase activity | 2.2989 | 8 | yes |
| GO:0003085 | negative regulation of systemic arterial blood pressure | 2.2989 | 5 | yes |
| GO:0031644 | regulation of nervous system process | 2.2989 | 5 | yes |
| GO:0032091 | negative regulation of protein binding | 2.2989 | 5 | yes |
| GO:0032147 | activation of protein kinase activity | 2.2989 | 8 | yes |
| GO:0035150 | regulation of tube size | 2.2989 | 4 | yes |
| GO:0035296 | regulation of tube diameter | 2.2989 | 5 | yes |
| GO:0040014 | regulation of multicellular organism growth | 2.2989 | 4 | yes |
| GO:0042311 | vasodilation | 2.2989 | 6 | yes |
| GO:0045776 | negative regulation of blood pressure | 2.2989 | 4 | yes |
| GO:0048640 | negative regulation of developmental growth | 2.2989 | 5 | yes |
| GO:0051100 | negative regulation of binding | 2.2989 | 4 | yes |
| GO:0051349 | positive regulation of lyase activity | 1.7241 | 5 | yes |
| GO:0071875 | adrenergic receptor signaling pathway | 1.7241 | 4 | yes |
| GO:0071880 | adenylate cyclase-activating adrenergic receptor signaling pathway | 1.7241 | 5 | yes |
| GO:0098815 | modulation of excitatory postsynaptic potential | 1.7241 | 4 | yes |
| GO:0120161 | regulation of cold-induced thermogenesis | 1.7241 | 4 | yes |
| GO:0120162 | positive regulation of cold-induced thermogenesis | 1.7241 | 5 | yes |
| GO:1904645 | response to amyloid-beta | 1.7241 | 4 | yes |
| GO:1904646 | cellular response to amyloid-beta | 1.7241 | 5 | yes |
| GO:2000311 | regulation of AMPA receptor activity | 1.7241 | 5 | yes |
| GO:2000463 | positive regulation of excitatory postsynaptic potential | 1.7241 | 5 | yes |
| GO:2000481 | positive regulation of cAMP-dependent protein kinase activity | 1.7241 | 9 | yes |
| GO:0002025 | norepinephrine-epinephrine-mediated vasodilation involved in regulation of systemic arterial blood pressure | 1.7241 | 6 | yes |
| GO:0002032 | desensitization of G protein-coupled receptor signaling pathway by arrestin | 1.7241 | 6 | yes |
| GO:0006939 | smooth muscle contraction | 1.7241 | 5 | yes |
| GO:0010738 | regulation of protein kinase A signaling | 1.7241 | 6 | yes |
| GO:0010739 | positive regulation of protein kinase A signaling | 1.7241 | 7 | yes |
| GO:0031281 | positive regulation of cyclase activity | 1.7241 | 5 | yes |
| GO:0031649 | heat generation | 1.7241 | 4 | yes |
| GO:0040015 | negative regulation of multicellular organism growth | 1.7241 | 5 | yes |
| GO:0043243 | positive regulation of protein-containing complex disassembly | 1.7241 | 6 | yes |
| GO:0045444 | fat cell differentiation | 1.7241 | 4 | yes |
| GO:0045453 | bone resorption | 1.7241 | 5 | yes |
| GO:0045762 | positive regulation of adenylate cyclase activity | 1.7241 | 6 | yes |
| GO:0045932 | negative regulation of muscle contraction | 1.7241 | 5 | yes |
| GO:0050873 | brown fat cell differentiation | 1.7241 | 5 | yes |
| GO:0061884 | regulation of mini excitatory postsynaptic potential | 1.1494 | 5 | yes |
| GO:0061885 | positive regulation of mini excitatory postsynaptic potential | 1.1494 | 6 | yes |
| GO:0070167 | regulation of biomineral tissue development | 1.1494 | 5 | yes |
| GO:0070169 | positive regulation of biomineral tissue development | 1.1494 | 5 | yes |
| GO:1901096 | regulation of autophagosome maturation | 1.1494 | 6 | yes |
| GO:1901098 | positive regulation of autophagosome maturation | 1.1494 | 7 | yes |
| GO:1904502 | regulation of lipophagy | 1.1494 | 8 | yes |
| GO:1904504 | positive regulation of lipophagy | 1.1494 | 9 | yes |
| GO:2000273 | positive regulation of signaling receptor activity | 1.1494 | 4 | yes |
| GO:2000969 | positive regulation of AMPA receptor activity | 1.1494 | 5 | yes |
| GO:0006940 | regulation of smooth muscle contraction | 1.1494 | 7 | yes |
| GO:0007171 | activation of transmembrane receptor protein tyrosine kinase activity | 1.1494 | 6 | yes |
| GO:0007190 | activation of adenylate cyclase activity | 1.1494 | 7 | yes |
| GO:0030278 | regulation of ossification | 1.1494 | 4 | yes |
| GO:0030500 | regulation of bone mineralization | 1.1494 | 5 | yes |
| GO:0030501 | positive regulation of bone mineralization | 1.1494 | 6 | yes |
| GO:0045778 | positive regulation of ossification | 1.1494 | 5 | yes |
| GO:0045986 | negative regulation of smooth muscle contraction | 1.1494 | 6 | yes |
Disease
No data found.
All partners
| Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
|---|---|---|---|---|
| CNR1_HUMAN | [view interactions] | Low throughput | no | yes |
| 5HT4R_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| 5HT2C_HUMAN | [view interactions] | Low throughput | no | no |
| ADRB1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| BECN2_HUMAN | [view interactions] | Low throughput | no | no |
| OPRD_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| KCNJ3_HUMAN | [view interactions] | Low throughput | no | yes |
| AKA12_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| ARBK1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| NEDD4_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| VHL_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| CUL2_HUMAN | [view interactions] | Low throughput | no | yes |
| ELOC_HUMAN | [view interactions] | Low throughput | no | no |
| EGLN3_HUMAN | [view interactions] | Low throughput | no | no |
| UBP20_HUMAN | [view interactions] | Low throughput | no | yes |
| MARH2_HUMAN | [view interactions] | Low throughput | no | yes |
| HGS_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| CLH1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| NHRF2_HUMAN | [view interactions] | Low throughput | no | no |
| TERA_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| EI2BA_HUMAN | [view interactions] | Low throughput | no | yes |
| UBC_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| UBP33_HUMAN | [view interactions] | Low throughput | no | yes |
| MAGI3_HUMAN | [view interactions] | Low throughput | no | no |
| ARRB2_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| ARRD3_HUMAN | [view interactions] | Low throughput | no | no |
| ERBB2_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| GBB1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| AA1R_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| ADRB2_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| GRB2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| SRC_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| DLG4_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| KCNK2_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| NHRF1_HUMAN | [view interactions] | Low throughput | no | no |
| CAC1C_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| CAV3_HUMAN | [view interactions] | Low throughput | no | no |
| HNRPK_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| MGLL_HUMAN | [view interactions] | Low throughput | no | yes |
| LAMP2_HUMAN | [view interactions] | Low throughput | no | yes |
| MBP_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| PRIO_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| GRK6_HUMAN | [view interactions] | Low throughput | no | yes |
| ARRD1_HUMAN | [view interactions] | Low throughput | no | yes |
| ARRD4_HUMAN | [view interactions] | Low throughput | no | yes |
| MLP3B_HUMAN | [view interactions] | Low throughput | no | yes |
| AP2A_HUMAN | [view interactions] | Low throughput | no | no |
| DRD4_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| ERAP1_HUMAN | [view interactions] | Low throughput | no | yes |
| UCHL1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| GRK1_HUMAN | [view interactions] | Low throughput | no | no |
| ARBK2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| GRK4_HUMAN | [view interactions] | Low throughput | no | yes |
| GRK5_HUMAN | [view interactions] | Low throughput | no | yes |
| MDM2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| GBG2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| PE2R1_HUMAN | [view interactions] | Low throughput | no | no |
| GNAI1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| EEA1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| PP2BA_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| KCNJ5_HUMAN | [view interactions] | Low throughput | no | yes |
| REL_HUMAN | [view interactions] | High throughput | no | yes |
| GBB2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GBB4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NSF_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GNAI3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| UBB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GBG12_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AMFR_HUMAN | [view interactions] | High throughput | no | yes |
| RNF5_HUMAN | [view interactions] | High throughput | no | yes |
| NPL4_HUMAN | [view interactions] | High throughput | no | yes |
| UFD1_HUMAN | [view interactions] | High throughput | no | no |
| BIP_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DJB11_HUMAN | [view interactions] | High throughput | no | yes |
| CALX_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| S61A1_HUMAN | [view interactions] | High throughput | no | no |
| PSMD2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ECM29_HUMAN | [view interactions] | High throughput | no | no |
| ATPA_HUMAN | [view interactions] | High throughput | no | yes |
| ATPB_HUMAN | [view interactions] | High throughput | no | yes |
| ATPG_HUMAN | [view interactions] | High throughput | no | yes |
| AT2A2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ACTG_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CLGN_HUMAN | [view interactions] | High throughput | no | no |
| CALM2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CALM3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CALM1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CPNS1_HUMAN | [view interactions] | High throughput | no | yes |
| CH60_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| C1QBP_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ODP2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RPN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ERLN2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| EF1A1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FKBP8_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| G3P_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SV2A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| F162A_HUMAN | [view interactions] | High throughput | no | yes |
| HS71B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HS71A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GRP75_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HNRPU_HUMAN | [view interactions] | High throughput | no | yes |
| MIC60_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| K2C1_HUMAN | [view interactions] | High throughput | no | no |
| K1C10_HUMAN | [view interactions] | High throughput | no | no |
| K22E_HUMAN | [view interactions] | High throughput | no | no |
| K2C5_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| K1C9_HUMAN | [view interactions] | High throughput | no | no |
| LPPRC_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AT1A1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| NDUA4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PO210_HUMAN | [view interactions] | High throughput | no | yes |
| PRKDC_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| VDAC2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PHB1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PHB2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ODPA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RPN2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MYLK2_HUMAN | [view interactions] | High throughput | no | no |
| ADT2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TOM70_HUMAN | [view interactions] | High throughput | no | yes |
| TMUB1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TMM33_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| EFTU_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TBB5_HUMAN | [view interactions] | High throughput | no | yes |
| TBB2A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| UBXN8_HUMAN | [view interactions] | High throughput | no | yes |
| CNNM3_HUMAN | [view interactions] | High throughput | no | yes |
| DAD1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DSG2_HUMAN | [view interactions] | High throughput | no | no |
| ETFB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| EF1B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| EF1D_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| EF1G_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| EF2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| IF4A1_HUMAN | [view interactions] | High throughput | no | no |
| FLNA_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| EFGM_HUMAN | [view interactions] | High throughput | no | yes |
| GCDH_HUMAN | [view interactions] | High throughput | no | yes |
| RACK1_HUMAN | [view interactions] | High throughput | no | yes |
| ROA2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HNRPF_HUMAN | [view interactions] | High throughput | no | yes |
| HNRH1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HLAB_HUMAN | [view interactions] | High throughput | no | yes |
| DHB12_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DHB4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HSDL2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HACL2_HUMAN | [view interactions] | High throughput | no | yes |
| IDHP_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| IDH3A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| IDH3G_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| IDH3B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| IMB1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LMNB1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HLAC_HUMAN | [view interactions] | High throughput | no | no |
| MCCB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| C1TM_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| C1TC_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ATPO_HUMAN | [view interactions] | High throughput | no | yes |
| LONM_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RM12_HUMAN | [view interactions] | High throughput | no | yes |
| ECHB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AT1B3_HUMAN | [view interactions] | High throughput | no | yes |
| NDUA5_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NDUS2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NDUS3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NDUV1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NU155_HUMAN | [view interactions] | High throughput | no | yes |
| NUP93_HUMAN | [view interactions] | High throughput | no | yes |
| OAT_HUMAN | [view interactions] | High throughput | no | yes |
| PON2_HUMAN | [view interactions] | High throughput | no | yes |
| AT2B4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PCBP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PCBP2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PGRC1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AIFM1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| PDIA6_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| P5CS_HUMAN | [view interactions] | High throughput | no | yes |
| PYC_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ODPB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RAB18_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RBP2_HUMAN | [view interactions] | High throughput | no | yes |
| RAN_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RLA1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RS5_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SC22B_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| SERPH_HUMAN | [view interactions] | High throughput | no | no |
| GLYM_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SPTC1_HUMAN | [view interactions] | High throughput | no | yes |
| MK14_HUMAN | [view interactions] | High throughput | no | yes |
| SRPRB_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| SSRD_HUMAN | [view interactions] | High throughput | no | yes |
| AAAT_HUMAN | [view interactions] | High throughput | no | no |
| DIC_HUMAN | [view interactions] | High throughput | no | yes |
| M2OM_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| S25A3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| S2513_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ADT3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| S39AE_HUMAN | [view interactions] | High throughput | no | yes |
| ITCH_HUMAN | [view interactions] | High throughput | no | yes |
| SLIRP_HUMAN | [view interactions] | High throughput | no | yes |
| STOM_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SYJ2B_HUMAN | [view interactions] | High throughput | no | no |
| TADBP_HUMAN | [view interactions] | High throughput | no | yes |
| TMX1_HUMAN | [view interactions] | High throughput | no | no |
| TITIN_HUMAN | [view interactions] | High throughput | no | no |
| TRAF1_HUMAN | [view interactions] | High throughput | no | no |
| TFR1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TIM50_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TM9S3_HUMAN | [view interactions] | High throughput | no | yes |
| CNBP_HUMAN | [view interactions] | High throughput | no | no |
| ENPL_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GRIA1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| QCR2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KAP2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| JKAMP_HUMAN | [view interactions] | High throughput | no | yes |
| GNB5_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| WNK1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| GRIA2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CD4_HUMAN | [view interactions] | High throughput | no | no |
| TSHR_HUMAN | [view interactions] | High throughput | no | no |
| CEAM1_HUMAN | [view interactions] | High throughput | no | no |
| CD9_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| JIP2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| PA2GD_HUMAN | [view interactions] | High throughput | no | no |
| ELL2_HUMAN | [view interactions] | High throughput | no | no |
| AGRG1_HUMAN | [view interactions] | High throughput | no | yes |
| SNW1_HUMAN | [view interactions] | High throughput | no | yes |
| STAT4_HUMAN | [view interactions] | High throughput | no | yes |
| RN138_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RNF41_HUMAN | [view interactions] | High throughput | no | yes |
| E2F8_HUMAN | [view interactions] | High throughput | no | yes |
| GDIR1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RN208_HUMAN | [view interactions] | High throughput | no | no |
| RGS11_HUMAN | [view interactions] | High throughput | no | yes |
| ATIF1_HUMAN | [view interactions] | High throughput | no | yes |
| ALDOA_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| EF1DL_HUMAN | [view interactions] | High throughput | no | no |
| GPC5B_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| TMM61_HUMAN | [view interactions] | High throughput | no | no |
| CD81_HUMAN | [view interactions] | High throughput | no | no |
| GUSP1_HUMAN | [view interactions] | High throughput | no | no |
| IL6RA_HUMAN | [view interactions] | High throughput | no | no |
| ADCY3_HUMAN | [view interactions] | High throughput | no | yes |
| CD68_HUMAN | [view interactions] | High throughput | no | no |
| ABCA7_HUMAN | [view interactions] | High throughput | no | yes |
| GNAT2_HUMAN | [view interactions] | High throughput | no | no |
| VATO_HUMAN | [view interactions] | High throughput | no | no |
| VA0D1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RGS10_HUMAN | [view interactions] | High throughput | no | yes |
| BACE1_HUMAN | [view interactions] | High throughput | no | yes |
| KCNE1_HUMAN | [view interactions] | High throughput | no | no |
| CENPB_HUMAN | [view interactions] | High throughput | no | yes |
| RHG05_HUMAN | [view interactions] | High throughput | no | yes |
| BAZ2A_HUMAN | [view interactions] | High throughput | no | no |
| MUC18_HUMAN | [view interactions] | High throughput | no | yes |
| RIOX1_HUMAN | [view interactions] | High throughput | no | no |
| GASR_HUMAN | [view interactions] | High throughput | no | no |
| MFS12_HUMAN | [view interactions] | High throughput | no | yes |
| CRYM_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CLP1L_HUMAN | [view interactions] | High throughput | no | yes |
| VIR_HUMAN | [view interactions] | High throughput | no | yes |
| CCND2_HUMAN | [view interactions] | High throughput | no | yes |
| GPR37_HUMAN | [view interactions] | High throughput | no | no |
| DJC14_HUMAN | [view interactions] | High throughput | no | yes |
| DCR1A_HUMAN | [view interactions] | High throughput | no | yes |
| CLAP2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| HS2ST_HUMAN | [view interactions] | High throughput | no | yes |
| GBP5_HUMAN | [view interactions] | High throughput | no | no |
| LRAT2_HUMAN | [view interactions] | High throughput | no | yes |
| FBX17_HUMAN | [view interactions] | High throughput | no | no |
| MITF_HUMAN | [view interactions] | High throughput | no | no |
| GNAI2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MBOA2_HUMAN | [view interactions] | High throughput | no | yes |
| MSRE_HUMAN | [view interactions] | High throughput | no | no |
| KLC1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| NPTX1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RHOD_HUMAN | [view interactions] | High throughput | no | no |
| NPAL2_HUMAN | [view interactions] | High throughput | no | yes |
| CNN1_HUMAN | [view interactions] | High throughput | no | no |
| RAB14_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GMPR2_HUMAN | [view interactions] | High throughput | no | yes |
| RTN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GNL3L_HUMAN | [view interactions] | High throughput | no | yes |
| PTGDS_HUMAN | [view interactions] | High throughput | no | yes |
| RGS8_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PGES2_HUMAN | [view interactions] | High throughput | no | yes |
| RGS17_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NCOR2_HUMAN | [view interactions] | High throughput | no | yes |
| HDAC6_HUMAN | [view interactions] | High throughput | no | yes |
| OBP2A_HUMAN | [view interactions] | High throughput | no | no |
| RB27A_HUMAN | [view interactions] | High throughput | no | yes |
| SACS_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| VDAC1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SUIS_HUMAN | [view interactions] | High throughput | no | no |
| RGS5_HUMAN | [view interactions] | High throughput | no | no |
| SPTN2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RAP2C_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| SYUA_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| TS101_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TSN7_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RGS2_HUMAN | [view interactions] | High throughput | no | no |
| TM187_HUMAN | [view interactions] | High throughput | no | no |
| RGS9_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| UST_HUMAN | [view interactions] | High throughput | no | yes |
| RAB3A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| 1433T_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| VEGFB_HUMAN | [view interactions] | High throughput | no | no |
| VAPA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SYUG_HUMAN | [view interactions] | High throughput | no | yes |
| DCA10_HUMAN | [view interactions] | High throughput | no | no |
| STAT3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| BASI_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ARF4_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ARV1_HUMAN | [view interactions] | High throughput | no | yes |
| GRIA3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| BACD1_HUMAN | [view interactions] | High throughput | no | no |
| RGS20_HUMAN | [view interactions] | High throughput | no | no |
| ZN254_HUMAN | [view interactions] | High throughput | no | no |
| ZNF25_HUMAN | [view interactions] | High throughput | no | no |
| VPS35_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MBRL_HUMAN | [view interactions] | High throughput | no | yes |
| AP2A1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MOG_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| AP2B1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NLS1_HUMAN | [view interactions] | High throughput | no | yes |
| AP2M1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GOGB1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CLCA_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| TF2B_HUMAN | [view interactions] | High throughput | no | yes |
| SNX27_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CXG2_HUMAN | [view interactions] | High throughput | no | no |
| VPS29_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| S52A2_HUMAN | [view interactions] | High throughput | no | no |
| VP26A_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| SENP3_HUMAN | [view interactions] | High throughput | no | yes |
| S39A4_HUMAN | [view interactions] | High throughput | no | no |
| G6PT2_HUMAN | [view interactions] | High throughput | no | yes |
| RGR_HUMAN | [view interactions] | High throughput | no | no |
| PRDX1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TCTA_HUMAN | [view interactions] | High throughput | no | yes |
| NAT14_HUMAN | [view interactions] | High throughput | no | no |
| TM144_HUMAN | [view interactions] | High throughput | no | no |
| YIPF5_HUMAN | [view interactions] | High throughput | no | yes |
| TMCC2_HUMAN | [view interactions] | High throughput | no | yes |
| TPTE_HUMAN | [view interactions] | High throughput | no | no |
| KCNJ6_HUMAN | [view entry] [view interactions] | High throughput | yes | no |