Features Interactions Isoform Disease Linear motifs Fingerprint Network All partners

TSN7_HUMAN

Evidence for PS localization

GO
G2C
SynGO
SynaptomeDB
HPA (protein expression in neurons)

Functions

May be involved in cell proliferation and cell motility. [View more on UniProt]

Protein features

Binary interactions with known binding regions

Interacting region for partners were not defined.

Network

Download full PS network for entry.

Isoforms

Disease-causing germline mutations

No data found.

Linear motifs

No annotated instance was found. To search for linear motifs, use the ELM prediction server.

Fingerprint

Molecular function

Term Name % Distance from the top of the tree Annotated in TSN7_HUMAN
GO:0098960 postsynaptic neurotransmitter receptor activity 31.2500 4 no
GO:0001540 amyloid-beta binding 31.2500 4 no
GO:0008179 adenylate cyclase binding 25.0000 4 no
GO:0019900 kinase binding 25.0000 4 no
GO:0019901 protein kinase binding 25.0000 5 no
GO:0046872 metal ion binding 25.0000 4 no
GO:0004930 G protein-coupled receptor activity 25.0000 4 no
GO:0004970 ionotropic glutamate receptor activity 25.0000 5 no
GO:0004971 AMPA glutamate receptor activity 25.0000 6 no
GO:0005216 ion channel activity 25.0000 4 no
GO:0005230 extracellular ligand-gated ion channel activity 25.0000 6 no
GO:0005261 cation channel activity 25.0000 5 no
GO:0008066 glutamate receptor activity 25.0000 4 no
GO:0008324 cation transmembrane transporter activity 25.0000 4 no
GO:0015267 channel activity 25.0000 4 no
GO:0015276 ligand-gated ion channel activity 25.0000 5 no
GO:0022824 transmitter-gated ion channel activity 25.0000 5 no
GO:0022834 ligand-gated channel activity 25.0000 6 no
GO:0022835 transmitter-gated channel activity 25.0000 4 no
GO:0022836 gated channel activity 25.0000 5 no
GO:0022890 inorganic cation transmembrane transporter activity 25.0000 4 no
GO:0099094 ligand-gated cation channel activity 25.0000 6 no

Biological process

Term Name % Distance from top the of the tree Annotated in TSN7_HUMAN
GO:0048523 negative regulation of cellular process 62.5000 4 no
GO:0010646 regulation of cell communication 56.2500 4 no
GO:0048522 positive regulation of cellular process 50.0000 4 no
GO:0009966 regulation of signal transduction 43.7500 4 no
GO:0044057 regulation of system process 43.7500 4 no
GO:0008104 protein localization 37.5000 4 no
GO:0009893 positive regulation of metabolic process 37.5000 4 no
GO:0010604 positive regulation of macromolecule metabolic process 37.5000 5 no
GO:0031323 regulation of cellular metabolic process 37.5000 4 no
GO:0031325 positive regulation of cellular metabolic process 37.5000 5 no
GO:0031399 regulation of protein modification process 37.5000 6 no
GO:0031401 positive regulation of protein modification process 37.5000 7 no
GO:0051049 regulation of transport 37.5000 4 no
GO:0051050 positive regulation of transport 37.5000 4 no
GO:0051128 regulation of cellular component organization 37.5000 4 no
GO:0051171 regulation of nitrogen compound metabolic process 37.5000 4 no
GO:0051173 positive regulation of nitrogen compound metabolic process 37.5000 5 no
GO:0051246 regulation of protein metabolic process 37.5000 5 no
GO:0051247 positive regulation of protein metabolic process 37.5000 6 no
GO:0060255 regulation of macromolecule metabolic process 37.5000 4 no
GO:0080090 regulation of primary metabolic process 37.5000 4 no
GO:0090257 regulation of muscle system process 37.5000 5 no
GO:1902531 regulation of intracellular signal transduction 37.5000 5 no
GO:0010648 negative regulation of cell communication 37.5000 5 no
GO:0023057 negative regulation of signaling 37.5000 4 no
GO:0001932 regulation of protein phosphorylation 31.2500 7 no
GO:0001934 positive regulation of protein phosphorylation 31.2500 8 no
GO:0006937 regulation of muscle contraction 31.2500 6 no
GO:0008016 regulation of heart contraction 31.2500 6 no
GO:0010562 positive regulation of phosphorus metabolic process 31.2500 6 no
GO:0010959 regulation of metal ion transport 31.2500 6 no
GO:0019220 regulation of phosphate metabolic process 31.2500 6 no
GO:0022898 regulation of transmembrane transporter activity 31.2500 4 no
GO:0032412 regulation of ion transmembrane transporter activity 31.2500 5 no
GO:0033674 positive regulation of kinase activity 31.2500 6 no
GO:0034762 regulation of transmembrane transport 31.2500 4 no
GO:0034765 regulation of ion transmembrane transport 31.2500 5 no
GO:0042325 regulation of phosphorylation 31.2500 7 no
GO:0042327 positive regulation of phosphorylation 31.2500 8 no
GO:0043085 positive regulation of catalytic activity 31.2500 4 no
GO:0043269 regulation of ion transport 31.2500 5 no
GO:0043270 positive regulation of ion transport 31.2500 5 no
GO:0043549 regulation of kinase activity 31.2500 5 no
GO:0045859 regulation of protein kinase activity 31.2500 6 no
GO:0045860 positive regulation of protein kinase activity 31.2500 7 no
GO:0045937 positive regulation of phosphate metabolic process 31.2500 7 no
GO:0050804 modulation of chemical synaptic transmission 31.2500 5 no
GO:0051174 regulation of phosphorus metabolic process 31.2500 5 no
GO:0051338 regulation of transferase activity 31.2500 4 no
GO:0051347 positive regulation of transferase activity 31.2500 5 no
GO:0099177 regulation of trans-synaptic signaling 31.2500 4 no
GO:1903522 regulation of blood circulation 31.2500 5 no
GO:1904062 regulation of cation transmembrane transport 31.2500 6 no
GO:2001257 regulation of cation channel activity 31.2500 6 no
GO:0007268 chemical synaptic transmission 31.2500 6 no
GO:0016192 vesicle-mediated transport 31.2500 4 no
GO:0098916 anterograde trans-synaptic signaling 31.2500 5 no
GO:0099537 trans-synaptic signaling 31.2500 4 no
GO:0001933 negative regulation of protein phosphorylation 25.0000 8 no
GO:0009892 negative regulation of metabolic process 25.0000 4 no
GO:0010038 response to metal ion 25.0000 4 no
GO:0010563 negative regulation of phosphorus metabolic process 25.0000 6 no
GO:0010564 regulation of cell cycle process 25.0000 5 no
GO:0010605 negative regulation of macromolecule metabolic process 25.0000 5 no
GO:0010921 regulation of phosphatase activity 25.0000 5 no
GO:0010941 regulation of cell death 25.0000 4 no
GO:0031324 negative regulation of cellular metabolic process 25.0000 5 no
GO:0031400 negative regulation of protein modification process 25.0000 7 no
GO:0032410 negative regulation of transporter activity 25.0000 4 no
GO:0032411 positive regulation of transporter activity 25.0000 4 no
GO:0032413 negative regulation of ion transmembrane transporter activity 25.0000 5 no
GO:0032414 positive regulation of ion transmembrane transporter activity 25.0000 5 no
GO:0032465 regulation of cytokinesis 25.0000 5 no
GO:0034763 negative regulation of transmembrane transport 25.0000 5 no
GO:0034764 positive regulation of transmembrane transport 25.0000 5 no
GO:0034766 negative regulation of ion transmembrane transport 25.0000 6 no
GO:0034767 positive regulation of ion transmembrane transport 25.0000 6 no
GO:0035303 regulation of dephosphorylation 25.0000 7 no
GO:0035304 regulation of protein dephosphorylation 25.0000 7 no
GO:0042326 negative regulation of phosphorylation 25.0000 8 no
GO:0043271 negative regulation of ion transport 25.0000 5 no
GO:0043666 regulation of phosphoprotein phosphatase activity 25.0000 6 no
GO:0045936 negative regulation of phosphate metabolic process 25.0000 7 no
GO:0051051 negative regulation of transport 25.0000 4 no
GO:0051172 negative regulation of nitrogen compound metabolic process 25.0000 5 no
GO:0051248 negative regulation of protein metabolic process 25.0000 6 no
GO:0051282 regulation of sequestering of calcium ion 25.0000 4 no
GO:0051302 regulation of cell division 25.0000 4 no
GO:0051336 regulation of hydrolase activity 25.0000 4 no
GO:0051726 regulation of cell cycle 25.0000 4 no
GO:0051924 regulation of calcium ion transport 25.0000 7 no
GO:0051926 negative regulation of calcium ion transport 25.0000 6 no
GO:0071900 regulation of protein serine/threonine kinase activity 25.0000 7 no
GO:0071902 positive regulation of protein serine/threonine kinase activity 25.0000 8 no
GO:1901019 regulation of calcium ion transmembrane transporter activity 25.0000 6 no
GO:1901020 negative regulation of calcium ion transmembrane transporter activity 25.0000 6 no
GO:1903169 regulation of calcium ion transmembrane transport 25.0000 7 no
GO:1903170 negative regulation of calcium ion transmembrane transport 25.0000 7 no
GO:1904063 negative regulation of cation transmembrane transport 25.0000 7 no
GO:1904064 positive regulation of cation transmembrane transport 25.0000 7 no
GO:2001258 negative regulation of cation channel activity 25.0000 6 no
GO:2001259 positive regulation of cation channel activity 25.0000 6 no
GO:0007188 adenylate cyclase-modulating G protein-coupled receptor signaling pathway 25.0000 4 no
GO:0009968 negative regulation of signal transduction 25.0000 5 no
GO:0048585 negative regulation of response to stimulus 25.0000 4 no
GO:0051130 positive regulation of cellular component organization 25.0000 5 no
GO:0071702 organic substance transport 25.0000 4 no

Disease

Term Name % Distance from top the of the tree Annotated in TSN7_HUMAN
DOID:0050700 cardiomyopathy 18.7500 4 no
DOID:0060036 intrinsic cardiomyopathy 18.7500 5 no
DOID:114 heart disease 18.7500 3 no
DOID:2843 long QT syndrome 12.5000 6 no

All partners

Uniprot ID Details Highest evidence Localizing into PSD HPA (protein expression in neurons)
ADCY5_HUMAN [view interactions] Low throughput no no
CAC1A_HUMAN [view interactions] High throughput no no
CREB3_HUMAN [view interactions] High throughput no no
HAVR2_HUMAN [view interactions] High throughput no no
RBL1_HUMAN [view interactions] High throughput no yes
GP152_HUMAN [view interactions] High throughput no no
F209A_HUMAN [view interactions] High throughput no no
LHPL5_HUMAN [view interactions] High throughput no no
ADRB2_HUMAN [view entry] [view interactions] High throughput yes no
CCR2_HUMAN [view interactions] High throughput no yes
CCR9_HUMAN [view interactions] High throughput no no
DRD2_HUMAN [view entry] [view interactions] High throughput yes no
BUD31_HUMAN [view interactions] High throughput no yes
GNRHR_HUMAN [view interactions] High throughput no no
GPR35_HUMAN [view interactions] High throughput no no
5HT4R_HUMAN [view interactions] High throughput no yes
LT4R2_HUMAN [view interactions] High throughput no no
ACM2_HUMAN [view entry] [view interactions] High throughput yes yes
ACM4_HUMAN [view entry] [view interactions] High throughput yes yes
OXYR_HUMAN [view interactions] High throughput no no
SMO_HUMAN [view interactions] High throughput no yes
BBS1_HUMAN [view interactions] High throughput no no
LMNA_HUMAN [view entry] [view interactions] High throughput yes yes
MEOX2_HUMAN [view interactions] High throughput no no
KPTN_HUMAN [view entry] [view interactions] High throughput yes yes
PLD5_HUMAN [view interactions] High throughput no no
CALM2_HUMAN [view entry] [view interactions] High throughput yes yes
CALM3_HUMAN [view entry] [view interactions] High throughput yes yes
CALM1_HUMAN [view entry] [view interactions] High throughput yes yes
GRIP1_HUMAN [view entry] [view interactions] Computational yes yes
GRIA2_HUMAN [view entry] [view interactions] Computational yes yes
GRIA4_HUMAN [view entry] [view interactions] Computational yes no
PICK1_HUMAN [view entry] [view interactions] Computational yes yes
GRIA3_HUMAN [view entry] [view interactions] Computational yes yes
GRIA1_HUMAN [view entry] [view interactions] Computational yes yes