DRD2_HUMAN
Dopamine receptor whose activity is mediated by G proteins which inhibit adenylyl cyclase (PubMed). Positively regulates postnatal regression of retinal hyaloid vessels via suppression of VEGFR2/KDR activity, downstream of OPN5 . [View more on UniProt]
To display all evidence describing the interaction with a partner, click on the protein name left to the bars.
No data found.
No annotated instance was found. To search for linear motifs, use the ELM prediction server.
Molecular function
Term | Name | % | Distance from the top of the tree | Annotated in DRD2_HUMAN |
---|---|---|---|---|
GO:0043169 | cation binding | 35.1852 | 4 | yes |
GO:0046872 | metal ion binding | 25.9259 | 5 | no |
GO:0004930 | G protein-coupled receptor activity | 22.2222 | 4 | yes |
GO:0019900 | kinase binding | 22.2222 | 4 | no |
GO:0098960 | postsynaptic neurotransmitter receptor activity | 12.9630 | 4 | yes |
GO:0099106 | ion channel regulator activity | 12.9630 | 4 | yes |
GO:0035254 | glutamate receptor binding | 11.1111 | 4 | yes |
GO:0035240 | dopamine binding | 9.2593 | 4 | yes |
GO:0004952 | dopamine neurotransmitter receptor activity | 7.4074 | 5 | yes |
GO:0015459 | potassium channel regulator activity | 7.4074 | 5 | yes |
GO:0035255 | ionotropic glutamate receptor binding | 7.4074 | 5 | yes |
GO:0001591 | dopamine neurotransmitter receptor activity, coupled via Gi/Go | 5.5556 | 6 | yes |
Biological process
Term | Name | % | Distance from top the of the tree | Annotated in DRD2_HUMAN |
---|---|---|---|---|
GO:0010646 | regulation of cell communication | 57.4074 | 4 | yes |
GO:0048522 | positive regulation of cellular process | 55.5556 | 4 | yes |
GO:0048523 | negative regulation of cellular process | 55.5556 | 4 | yes |
GO:0060255 | regulation of macromolecule metabolic process | 50.0000 | 4 | yes |
GO:0080090 | regulation of primary metabolic process | 50.0000 | 4 | yes |
GO:0051049 | regulation of transport | 48.1481 | 4 | yes |
GO:0031323 | regulation of cellular metabolic process | 44.4444 | 4 | yes |
GO:0009966 | regulation of signal transduction | 42.5926 | 4 | yes |
GO:0051246 | regulation of protein metabolic process | 40.7407 | 5 | yes |
GO:0023056 | positive regulation of signaling | 38.8889 | 4 | yes |
GO:0009893 | positive regulation of metabolic process | 37.0370 | 4 | yes |
GO:0010647 | positive regulation of cell communication | 37.0370 | 5 | yes |
GO:0022607 | cellular component assembly | 35.1852 | 4 | yes |
GO:0051050 | positive regulation of transport | 35.1852 | 4 | yes |
GO:0051128 | regulation of cellular component organization | 35.1852 | 4 | yes |
GO:1902531 | regulation of intracellular signal transduction | 35.1852 | 5 | yes |
GO:0048584 | positive regulation of response to stimulus | 33.3333 | 4 | yes |
GO:0008104 | protein localization | 33.3333 | 4 | yes |
GO:0009889 | regulation of biosynthetic process | 31.4815 | 4 | yes |
GO:0009892 | negative regulation of metabolic process | 31.4815 | 4 | yes |
GO:0010604 | positive regulation of macromolecule metabolic process | 31.4815 | 5 | yes |
GO:0031325 | positive regulation of cellular metabolic process | 29.6296 | 5 | yes |
GO:0050804 | modulation of chemical synaptic transmission | 29.6296 | 5 | yes |
GO:0071702 | organic substance transport | 29.6296 | 4 | yes |
GO:0009967 | positive regulation of signal transduction | 29.6296 | 5 | yes |
GO:0099177 | regulation of trans-synaptic signaling | 29.6296 | 4 | yes |
GO:0010605 | negative regulation of macromolecule metabolic process | 29.6296 | 5 | yes |
GO:0023057 | negative regulation of signaling | 27.7778 | 4 | yes |
GO:0031326 | regulation of cellular biosynthetic process | 27.7778 | 5 | yes |
GO:0031399 | regulation of protein modification process | 27.7778 | 6 | yes |
GO:0051248 | negative regulation of protein metabolic process | 27.7778 | 6 | yes |
GO:0006811 | monoatomic ion transport | 27.7778 | 4 | yes |
GO:0010648 | negative regulation of cell communication | 27.7778 | 5 | yes |
GO:0030030 | cell projection organization | 25.9259 | 4 | yes |
GO:0034762 | regulation of transmembrane transport | 25.9259 | 4 | yes |
GO:0043269 | regulation of monoatomic ion transport | 25.9259 | 5 | yes |
GO:0051094 | positive regulation of developmental process | 25.9259 | 4 | yes |
GO:0051240 | positive regulation of multicellular organismal process | 25.9259 | 4 | yes |
GO:0098657 | import into cell | 25.9259 | 4 | yes |
GO:0010556 | regulation of macromolecule biosynthetic process | 25.9259 | 5 | yes |
GO:0030001 | metal ion transport | 24.0741 | 6 | yes |
GO:0032880 | regulation of protein localization | 24.0741 | 5 | yes |
GO:0042325 | regulation of phosphorylation | 24.0741 | 7 | yes |
GO:0048585 | negative regulation of response to stimulus | 24.0741 | 4 | yes |
GO:0051174 | regulation of phosphorus metabolic process | 24.0741 | 5 | yes |
GO:0001932 | regulation of protein phosphorylation | 24.0741 | 7 | yes |
GO:0006812 | monoatomic cation transport | 24.0741 | 5 | yes |
GO:0007188 | adenylate cyclase-modulating G protein-coupled receptor signaling pathway | 24.0741 | 4 | yes |
GO:0060341 | regulation of cellular localization | 24.0741 | 4 | yes |
GO:0071705 | nitrogen compound transport | 24.0741 | 4 | yes |
GO:0010468 | regulation of gene expression | 24.0741 | 6 | yes |
GO:0010959 | regulation of metal ion transport | 24.0741 | 6 | yes |
GO:0014070 | response to organic cyclic compound | 24.0741 | 4 | yes |
GO:0019220 | regulation of phosphate metabolic process | 24.0741 | 6 | yes |
GO:0006996 | organelle organization | 22.2222 | 4 | no |
GO:0051247 | positive regulation of protein metabolic process | 22.2222 | 6 | no |
GO:0031324 | negative regulation of cellular metabolic process | 22.2222 | 5 | yes |
GO:0042127 | regulation of cell population proliferation | 22.2222 | 4 | yes |
GO:0051046 | regulation of secretion | 22.2222 | 5 | yes |
GO:0051051 | negative regulation of transport | 22.2222 | 4 | yes |
GO:0007268 | chemical synaptic transmission | 22.2222 | 7 | yes |
GO:0098916 | anterograde trans-synaptic signaling | 22.2222 | 6 | yes |
GO:0010243 | response to organonitrogen compound | 22.2222 | 4 | yes |
GO:0099536 | synaptic signaling | 22.2222 | 4 | yes |
GO:0099537 | trans-synaptic signaling | 22.2222 | 5 | yes |
GO:1902533 | positive regulation of intracellular signal transduction | 22.2222 | 6 | yes |
GO:0042981 | regulation of apoptotic process | 20.3704 | 5 | no |
GO:0043067 | regulation of programmed cell death | 20.3704 | 4 | no |
GO:0034765 | regulation of monoatomic ion transmembrane transport | 20.3704 | 5 | yes |
GO:0051924 | regulation of calcium ion transport | 20.3704 | 7 | yes |
GO:0009891 | positive regulation of biosynthetic process | 20.3704 | 5 | yes |
GO:0010038 | response to metal ion | 20.3704 | 4 | yes |
GO:1903530 | regulation of secretion by cell | 20.3704 | 4 | yes |
GO:0019219 | regulation of nucleobase-containing compound metabolic process | 20.3704 | 5 | yes |
GO:2001141 | regulation of RNA biosynthetic process | 18.5185 | 6 | yes |
GO:0032101 | regulation of response to external stimulus | 18.5185 | 4 | yes |
GO:0044057 | regulation of system process | 18.5185 | 4 | yes |
GO:0051130 | positive regulation of cellular component organization | 18.5185 | 5 | yes |
GO:0051252 | regulation of RNA metabolic process | 18.5185 | 5 | yes |
GO:0006355 | regulation of DNA-templated transcription | 18.5185 | 7 | yes |
GO:0060627 | regulation of vesicle-mediated transport | 18.5185 | 4 | yes |
GO:0080134 | regulation of response to stress | 18.5185 | 4 | yes |
GO:0009968 | negative regulation of signal transduction | 18.5185 | 5 | yes |
GO:1904062 | regulation of monoatomic cation transmembrane transport | 18.5185 | 6 | yes |
GO:0022898 | regulation of transmembrane transporter activity | 16.6667 | 4 | yes |
GO:0030003 | intracellular monoatomic cation homeostasis | 16.6667 | 5 | yes |
GO:0031328 | positive regulation of cellular biosynthetic process | 16.6667 | 6 | yes |
GO:0031400 | negative regulation of protein modification process | 16.6667 | 7 | yes |
GO:0032412 | regulation of monoatomic ion transmembrane transporter activity | 16.6667 | 5 | yes |
GO:0050890 | cognition | 16.6667 | 4 | yes |
GO:0051223 | regulation of protein transport | 16.6667 | 5 | yes |
GO:0051282 | regulation of sequestering of calcium ion | 16.6667 | 4 | yes |
GO:0051726 | regulation of cell cycle | 16.6667 | 4 | yes |
GO:0051952 | regulation of amine transport | 16.6667 | 5 | yes |
GO:0006873 | intracellular monoatomic ion homeostasis | 16.6667 | 4 | yes |
GO:0055080 | monoatomic cation homeostasis | 16.6667 | 4 | yes |
GO:0007193 | adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway | 16.6667 | 5 | yes |
GO:0070201 | regulation of establishment of protein localization | 16.6667 | 6 | yes |
GO:0010564 | regulation of cell cycle process | 16.6667 | 5 | yes |
GO:1903169 | regulation of calcium ion transmembrane transport | 16.6667 | 7 | yes |
GO:1903522 | regulation of blood circulation | 16.6667 | 5 | yes |
GO:2000145 | regulation of cell motility | 14.8148 | 4 | yes |
GO:0030334 | regulation of cell migration | 14.8148 | 5 | yes |
GO:0031623 | receptor internalization | 14.8148 | 5 | yes |
GO:0034763 | negative regulation of transmembrane transport | 14.8148 | 5 | yes |
GO:0043271 | negative regulation of monoatomic ion transport | 14.8148 | 5 | yes |
GO:0043279 | response to alkaloid | 14.8148 | 5 | yes |
GO:0043408 | regulation of MAPK cascade | 14.8148 | 6 | yes |
GO:0043410 | positive regulation of MAPK cascade | 14.8148 | 7 | yes |
GO:0045595 | regulation of cell differentiation | 14.8148 | 4 | yes |
GO:0051047 | positive regulation of secretion | 14.8148 | 5 | yes |
GO:0055074 | calcium ion homeostasis | 14.8148 | 4 | yes |
GO:0006874 | intracellular calcium ion homeostasis | 14.8148 | 5 | yes |
GO:0006898 | receptor-mediated endocytosis | 14.8148 | 4 | yes |
GO:0007200 | phospholipase C-activating G protein-coupled receptor signaling pathway | 14.8148 | 4 | yes |
GO:0007600 | sensory perception | 14.8148 | 4 | yes |
GO:0008016 | regulation of heart contraction | 14.8148 | 6 | yes |
GO:0098655 | monoatomic cation transmembrane transport | 14.8148 | 4 | yes |
GO:0098662 | inorganic cation transmembrane transport | 14.8148 | 4 | yes |
GO:0010557 | positive regulation of macromolecule biosynthetic process | 14.8148 | 6 | yes |
GO:0141124 | intracellular signaling cassette | 14.8148 | 4 | yes |
GO:1902532 | negative regulation of intracellular signal transduction | 14.8148 | 6 | yes |
GO:2000026 | regulation of multicellular organismal development | 12.9630 | 4 | yes |
GO:2001257 | regulation of cation channel activity | 12.9630 | 6 | yes |
GO:2001258 | negative regulation of cation channel activity | 12.9630 | 6 | yes |
GO:0030100 | regulation of endocytosis | 12.9630 | 5 | yes |
GO:0032410 | negative regulation of transporter activity | 12.9630 | 4 | yes |
GO:0032413 | negative regulation of ion transmembrane transporter activity | 12.9630 | 5 | yes |
GO:0034766 | negative regulation of monoatomic ion transmembrane transport | 12.9630 | 6 | yes |
GO:0042326 | negative regulation of phosphorylation | 12.9630 | 8 | yes |
GO:0045597 | positive regulation of cell differentiation | 12.9630 | 5 | yes |
GO:0045936 | negative regulation of phosphate metabolic process | 12.9630 | 7 | yes |
GO:0048259 | regulation of receptor-mediated endocytosis | 12.9630 | 6 | yes |
GO:0050708 | regulation of protein secretion | 12.9630 | 5 | yes |
GO:0050805 | negative regulation of synaptic transmission | 12.9630 | 5 | yes |
GO:0050806 | positive regulation of synaptic transmission | 12.9630 | 5 | yes |
GO:0051241 | negative regulation of multicellular organismal process | 12.9630 | 4 | yes |
GO:0001933 | negative regulation of protein phosphorylation | 12.9630 | 8 | yes |
GO:0002090 | regulation of receptor internalization | 12.9630 | 7 | yes |
GO:0051926 | negative regulation of calcium ion transport | 12.9630 | 6 | yes |
GO:0007189 | adenylate cyclase-activating G protein-coupled receptor signaling pathway | 12.9630 | 5 | yes |
GO:0008284 | positive regulation of cell population proliferation | 12.9630 | 5 | yes |
GO:0010563 | negative regulation of phosphorus metabolic process | 12.9630 | 6 | yes |
GO:1901019 | regulation of calcium ion transmembrane transporter activity | 12.9630 | 6 | yes |
GO:1901020 | negative regulation of calcium ion transmembrane transporter activity | 12.9630 | 6 | yes |
GO:0014075 | response to amine | 12.9630 | 5 | yes |
GO:1903170 | negative regulation of calcium ion transmembrane transport | 12.9630 | 7 | yes |
GO:1903532 | positive regulation of secretion by cell | 12.9630 | 5 | yes |
GO:1904063 | negative regulation of cation transmembrane transport | 12.9630 | 7 | yes |
GO:0031347 | regulation of defense response | 11.1111 | 5 | yes |
GO:0032102 | negative regulation of response to external stimulus | 11.1111 | 5 | yes |
GO:0034330 | cell junction organization | 11.1111 | 4 | yes |
GO:0042220 | response to cocaine | 11.1111 | 4 | yes |
GO:0046903 | secretion | 11.1111 | 4 | yes |
GO:0048638 | regulation of developmental growth | 11.1111 | 4 | yes |
GO:0048812 | neuron projection morphogenesis | 11.1111 | 5 | yes |
GO:0050433 | regulation of catecholamine secretion | 11.1111 | 5 | yes |
GO:0050808 | synapse organization | 11.1111 | 5 | yes |
GO:0001975 | response to amphetamine | 11.1111 | 6 | yes |
GO:0051588 | regulation of neurotransmitter transport | 11.1111 | 5 | yes |
GO:0006357 | regulation of transcription by RNA polymerase II | 11.1111 | 8 | yes |
GO:0051954 | positive regulation of amine transport | 11.1111 | 5 | yes |
GO:0051960 | regulation of nervous system development | 11.1111 | 5 | yes |
GO:0006816 | calcium ion transport | 11.1111 | 7 | yes |
GO:0051966 | regulation of synaptic transmission, glutamatergic | 11.1111 | 6 | yes |
GO:0070372 | regulation of ERK1 and ERK2 cascade | 11.1111 | 7 | yes |
GO:0070374 | positive regulation of ERK1 and ERK2 cascade | 11.1111 | 8 | yes |
GO:0007612 | learning | 11.1111 | 4 | yes |
GO:0007613 | memory | 11.1111 | 4 | yes |
GO:0080135 | regulation of cellular response to stress | 11.1111 | 4 | yes |
GO:0008285 | negative regulation of cell population proliferation | 11.1111 | 5 | yes |
GO:0008344 | adult locomotory behavior | 11.1111 | 4 | yes |
GO:0099171 | presynaptic modulation of chemical synaptic transmission | 11.1111 | 6 | yes |
GO:0120039 | plasma membrane bounded cell projection morphogenesis | 11.1111 | 4 | yes |
GO:0010628 | positive regulation of gene expression | 11.1111 | 7 | yes |
GO:1901385 | regulation of voltage-gated calcium channel activity | 11.1111 | 7 | yes |
GO:1901386 | negative regulation of voltage-gated calcium channel activity | 11.1111 | 7 | yes |
GO:0018958 | phenol-containing compound metabolic process | 11.1111 | 4 | yes |
GO:0021885 | forebrain cell migration | 9.2593 | 4 | yes |
GO:0022029 | telencephalon cell migration | 9.2593 | 5 | yes |
GO:0032465 | regulation of cytokinesis | 9.2593 | 5 | yes |
GO:0042417 | dopamine metabolic process | 9.2593 | 7 | yes |
GO:0043266 | regulation of potassium ion transport | 9.2593 | 7 | yes |
GO:0045927 | positive regulation of growth | 9.2593 | 4 | yes |
GO:0045935 | positive regulation of nucleobase-containing compound metabolic process | 9.2593 | 5 | yes |
GO:0046883 | regulation of hormone secretion | 9.2593 | 4 | yes |
GO:0046887 | positive regulation of hormone secretion | 9.2593 | 5 | yes |
GO:0048148 | behavioral response to cocaine | 9.2593 | 4 | yes |
GO:0050767 | regulation of neurogenesis | 9.2593 | 6 | yes |
GO:0050776 | regulation of immune response | 9.2593 | 4 | yes |
GO:0051048 | negative regulation of secretion | 9.2593 | 5 | yes |
GO:0051302 | regulation of cell division | 9.2593 | 4 | yes |
GO:0001764 | neuron migration | 9.2593 | 4 | yes |
GO:0001817 | regulation of cytokine production | 9.2593 | 4 | yes |
GO:0006576 | biogenic amine metabolic process | 9.2593 | 5 | yes |
GO:0006584 | catecholamine metabolic process | 9.2593 | 6 | yes |
GO:0051962 | positive regulation of nervous system development | 9.2593 | 5 | yes |
GO:0060078 | regulation of postsynaptic membrane potential | 9.2593 | 4 | yes |
GO:0060134 | prepulse inhibition | 9.2593 | 6 | yes |
GO:0060284 | regulation of cell development | 9.2593 | 5 | yes |
GO:0070588 | calcium ion transmembrane transport | 9.2593 | 5 | yes |
GO:0009308 | amine metabolic process | 9.2593 | 4 | yes |
GO:0009416 | response to light stimulus | 9.2593 | 4 | yes |
GO:0009712 | catechol-containing compound metabolic process | 9.2593 | 5 | yes |
GO:0014059 | regulation of dopamine secretion | 9.2593 | 6 | yes |
GO:0015711 | organic anion transport | 9.2593 | 5 | yes |
GO:1903531 | negative regulation of secretion by cell | 9.2593 | 5 | yes |
GO:1903828 | negative regulation of protein localization | 9.2593 | 5 | yes |
GO:1904950 | negative regulation of establishment of protein localization | 7.4074 | 6 | yes |
GO:2000177 | regulation of neural precursor cell proliferation | 7.4074 | 5 | yes |
GO:2000179 | positive regulation of neural precursor cell proliferation | 7.4074 | 6 | yes |
GO:2001222 | regulation of neuron migration | 7.4074 | 6 | yes |
GO:0031279 | regulation of cyclase activity | 7.4074 | 4 | yes |
GO:0031348 | negative regulation of defense response | 7.4074 | 5 | yes |
GO:0032228 | regulation of synaptic transmission, GABAergic | 7.4074 | 6 | yes |
GO:0034329 | cell junction assembly | 7.4074 | 5 | yes |
GO:0036293 | response to decreased oxygen levels | 7.4074 | 4 | yes |
GO:0045088 | regulation of innate immune response | 7.4074 | 5 | yes |
GO:0045761 | regulation of adenylate cyclase activity | 7.4074 | 5 | yes |
GO:0045807 | positive regulation of endocytosis | 7.4074 | 5 | yes |
GO:0045893 | positive regulation of DNA-templated transcription | 7.4074 | 8 | yes |
GO:0046942 | carboxylic acid transport | 7.4074 | 6 | yes |
GO:0048149 | behavioral response to ethanol | 7.4074 | 4 | yes |
GO:0048260 | positive regulation of receptor-mediated endocytosis | 7.4074 | 6 | yes |
GO:0048639 | positive regulation of developmental growth | 7.4074 | 5 | yes |
GO:0050709 | negative regulation of protein secretion | 7.4074 | 6 | yes |
GO:0050769 | positive regulation of neurogenesis | 7.4074 | 6 | yes |
GO:0050795 | regulation of behavior | 7.4074 | 4 | yes |
GO:0050807 | regulation of synapse organization | 7.4074 | 5 | yes |
GO:0051209 | release of sequestered calcium ion into cytosol | 7.4074 | 6 | yes |
GO:0051224 | negative regulation of protein transport | 7.4074 | 5 | yes |
GO:0051254 | positive regulation of RNA metabolic process | 7.4074 | 6 | yes |
GO:0051283 | negative regulation of sequestering of calcium ion | 7.4074 | 5 | yes |
GO:0001504 | neurotransmitter uptake | 7.4074 | 5 | yes |
GO:0051339 | regulation of lyase activity | 7.4074 | 4 | yes |
GO:0051580 | regulation of neurotransmitter uptake | 7.4074 | 6 | yes |
GO:0051584 | regulation of dopamine uptake involved in synaptic transmission | 7.4074 | 7 | yes |
GO:0051590 | positive regulation of neurotransmitter transport | 7.4074 | 5 | yes |
GO:0002031 | G protein-coupled receptor internalization | 7.4074 | 6 | yes |
GO:0002092 | positive regulation of receptor internalization | 7.4074 | 7 | yes |
GO:0051896 | regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction | 7.4074 | 6 | yes |
GO:0002683 | negative regulation of immune system process | 7.4074 | 4 | yes |
GO:0002791 | regulation of peptide secretion | 7.4074 | 6 | yes |
GO:0002793 | positive regulation of peptide secretion | 7.4074 | 6 | yes |
GO:0002831 | regulation of response to biotic stimulus | 7.4074 | 4 | yes |
GO:0051937 | catecholamine transport | 7.4074 | 6 | yes |
GO:0051940 | regulation of catecholamine uptake involved in synaptic transmission | 7.4074 | 6 | yes |
GO:0006836 | neurotransmitter transport | 7.4074 | 4 | yes |
GO:0006869 | lipid transport | 7.4074 | 5 | yes |
GO:0060079 | excitatory postsynaptic potential | 7.4074 | 5 | yes |
GO:0006936 | muscle contraction | 7.4074 | 4 | yes |
GO:0006939 | smooth muscle contraction | 7.4074 | 5 | yes |
GO:0007195 | adenylate cyclase-inhibiting dopamine receptor signaling pathway | 7.4074 | 4 | yes |
GO:0007416 | synapse assembly | 7.4074 | 6 | yes |
GO:0007606 | sensory perception of chemical stimulus | 7.4074 | 5 | yes |
GO:0007628 | adult walking behavior | 7.4074 | 5 | yes |
GO:0008277 | regulation of G protein-coupled receptor signaling pathway | 7.4074 | 5 | yes |
GO:0090087 | regulation of peptide transport | 7.4074 | 5 | yes |
GO:0090276 | regulation of peptide hormone secretion | 7.4074 | 5 | yes |
GO:0008306 | associative learning | 7.4074 | 5 | yes |
GO:0090277 | positive regulation of peptide hormone secretion | 7.4074 | 6 | yes |
GO:0090659 | walking behavior | 7.4074 | 4 | yes |
GO:0097553 | calcium ion transmembrane import into cytosol | 7.4074 | 6 | yes |
GO:0098810 | neurotransmitter reuptake | 7.4074 | 4 | yes |
GO:0010039 | response to iron ion | 7.4074 | 5 | yes |
GO:0010720 | positive regulation of cell development | 7.4074 | 6 | yes |
GO:1902680 | positive regulation of RNA biosynthetic process | 7.4074 | 7 | yes |
GO:0015844 | monoamine transport | 7.4074 | 5 | yes |
GO:0015849 | organic acid transport | 7.4074 | 5 | yes |
GO:0015850 | organic hydroxy compound transport | 7.4074 | 5 | yes |
GO:0015872 | dopamine transport | 7.4074 | 7 | yes |
GO:0016055 | Wnt signaling pathway | 7.4074 | 4 | yes |
GO:0021826 | substrate-independent telencephalic tangential migration | 5.5556 | 6 | yes |
GO:0021830 | interneuron migration from the subpallium to the cortex | 5.5556 | 8 | yes |
GO:0021843 | substrate-independent telencephalic tangential interneuron migration | 5.5556 | 7 | yes |
GO:0021853 | cerebral cortex GABAergic interneuron migration | 5.5556 | 6 | yes |
GO:2000146 | negative regulation of cell motility | 5.5556 | 5 | yes |
GO:0030336 | negative regulation of cell migration | 5.5556 | 6 | yes |
GO:0030432 | peristalsis | 5.5556 | 7 | yes |
GO:0031280 | negative regulation of cyclase activity | 5.5556 | 5 | yes |
GO:0032309 | icosanoid secretion | 5.5556 | 5 | yes |
GO:0033602 | negative regulation of dopamine secretion | 5.5556 | 7 | yes |
GO:0033604 | negative regulation of catecholamine secretion | 5.5556 | 6 | yes |
GO:0034776 | response to histamine | 5.5556 | 5 | yes |
GO:0035809 | regulation of urine volume | 5.5556 | 4 | yes |
GO:0035810 | positive regulation of urine volume | 5.5556 | 5 | yes |
GO:0040013 | negative regulation of locomotion | 5.5556 | 4 | yes |
GO:0040014 | regulation of multicellular organism growth | 5.5556 | 4 | yes |
GO:0040018 | positive regulation of multicellular organism growth | 5.5556 | 5 | yes |
GO:0042749 | regulation of circadian sleep/wake cycle | 5.5556 | 4 | yes |
GO:0043086 | negative regulation of catalytic activity | 5.5556 | 4 | yes |
GO:0043278 | response to morphine | 5.5556 | 6 | yes |
GO:0043491 | phosphatidylinositol 3-kinase/protein kinase B signal transduction | 5.5556 | 5 | yes |
GO:0045187 | regulation of circadian sleep/wake cycle, sleep | 5.5556 | 5 | yes |
GO:0045787 | positive regulation of cell cycle | 5.5556 | 5 | yes |
GO:0045824 | negative regulation of innate immune response | 5.5556 | 6 | yes |
GO:0045944 | positive regulation of transcription by RNA polymerase II | 5.5556 | 9 | yes |
GO:0048168 | regulation of neuronal synaptic plasticity | 5.5556 | 4 | yes |
GO:0048169 | regulation of long-term neuronal synaptic plasticity | 5.5556 | 5 | yes |
GO:0050482 | arachidonic acid secretion | 5.5556 | 6 | yes |
GO:0050678 | regulation of epithelial cell proliferation | 5.5556 | 5 | yes |
GO:0050777 | negative regulation of immune response | 5.5556 | 5 | yes |
GO:0050796 | regulation of insulin secretion | 5.5556 | 6 | yes |
GO:0051350 | negative regulation of lyase activity | 5.5556 | 5 | yes |
GO:0001819 | positive regulation of cytokine production | 5.5556 | 5 | yes |
GO:0051582 | positive regulation of neurotransmitter uptake | 5.5556 | 6 | yes |
GO:0051583 | dopamine uptake involved in synaptic transmission | 5.5556 | 6 | yes |
GO:0051586 | positive regulation of dopamine uptake involved in synaptic transmission | 5.5556 | 7 | yes |
GO:0002028 | regulation of sodium ion transport | 5.5556 | 7 | yes |
GO:0002052 | positive regulation of neuroblast proliferation | 5.5556 | 7 | yes |
GO:0051898 | negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction | 5.5556 | 7 | yes |
GO:0051934 | catecholamine uptake involved in synaptic transmission | 5.5556 | 5 | yes |
GO:0002832 | negative regulation of response to biotic stimulus | 5.5556 | 5 | yes |
GO:0051944 | positive regulation of catecholamine uptake involved in synaptic transmission | 5.5556 | 6 | yes |
GO:0051953 | negative regulation of amine transport | 5.5556 | 5 | yes |
GO:0051967 | negative regulation of synaptic transmission, glutamatergic | 5.5556 | 6 | yes |
GO:0060123 | regulation of growth hormone secretion | 5.5556 | 6 | yes |
GO:0060124 | positive regulation of growth hormone secretion | 5.5556 | 7 | yes |
GO:0060158 | phospholipase C-activating dopamine receptor signaling pathway | 5.5556 | 4 | yes |
GO:0007194 | negative regulation of adenylate cyclase activity | 5.5556 | 6 | yes |
GO:0007409 | axonogenesis | 5.5556 | 6 | yes |
GO:0007608 | sensory perception of smell | 5.5556 | 6 | yes |
GO:0071715 | icosanoid transport | 5.5556 | 7 | yes |
GO:0071875 | adrenergic receptor signaling pathway | 5.5556 | 4 | yes |
GO:0007616 | long-term memory | 5.5556 | 5 | yes |
GO:0071880 | adenylate cyclase-activating adrenergic receptor signaling pathway | 5.5556 | 5 | yes |
GO:0090068 | positive regulation of cell cycle process | 5.5556 | 6 | yes |
GO:0008542 | visual learning | 5.5556 | 4 | yes |
GO:0090493 | catecholamine uptake | 5.5556 | 7 | yes |
GO:0090494 | dopamine uptake | 5.5556 | 8 | yes |
GO:1900271 | regulation of long-term synaptic potentiation | 5.5556 | 4 | yes |
GO:1900273 | positive regulation of long-term synaptic potentiation | 5.5556 | 5 | yes |
GO:0014072 | response to isoquinoline alkaloid | 5.5556 | 5 | yes |
GO:0014821 | phasic smooth muscle contraction | 5.5556 | 6 | yes |
GO:1902692 | regulation of neuroblast proliferation | 5.5556 | 6 | yes |
GO:0015718 | monocarboxylic acid transport | 5.5556 | 7 | yes |
GO:0015908 | fatty acid transport | 5.5556 | 6 | yes |
GO:0015909 | long-chain fatty acid transport | 5.5556 | 7 | yes |
GO:1903963 | arachidonate transport | 5.5556 | 8 | yes |
GO:1904936 | interneuron migration | 5.5556 | 5 | yes |
GO:2001223 | negative regulation of neuron migration | 3.7037 | 7 | yes |
GO:0031223 | auditory behavior | 3.7037 | 4 | yes |
GO:0032467 | positive regulation of cytokinesis | 3.7037 | 6 | yes |
GO:0035813 | regulation of renal sodium excretion | 3.7037 | 6 | yes |
GO:0035815 | positive regulation of renal sodium excretion | 3.7037 | 5 | yes |
GO:0042321 | negative regulation of circadian sleep/wake cycle, sleep | 3.7037 | 5 | yes |
GO:0042754 | negative regulation of circadian rhythm | 3.7037 | 4 | yes |
GO:0042756 | drinking behavior | 3.7037 | 4 | yes |
GO:0044062 | regulation of excretion | 3.7037 | 5 | yes |
GO:0045745 | positive regulation of G protein-coupled receptor signaling pathway | 3.7037 | 6 | yes |
GO:0045776 | negative regulation of blood pressure | 3.7037 | 4 | yes |
GO:0046676 | negative regulation of insulin secretion | 3.7037 | 7 | yes |
GO:0046717 | acid secretion | 3.7037 | 5 | yes |
GO:0046888 | negative regulation of hormone secretion | 3.7037 | 5 | yes |
GO:0048521 | negative regulation of behavior | 3.7037 | 5 | yes |
GO:0048678 | response to axon injury | 3.7037 | 4 | yes |
GO:0050680 | negative regulation of epithelial cell proliferation | 3.7037 | 6 | yes |
GO:0001976 | nervous system process involved in regulation of systemic arterial blood pressure | 3.7037 | 4 | yes |
GO:0051781 | positive regulation of cell division | 3.7037 | 5 | yes |
GO:0051823 | regulation of synapse structural plasticity | 3.7037 | 6 | yes |
GO:0002792 | negative regulation of peptide secretion | 3.7037 | 6 | yes |
GO:0060159 | regulation of dopamine receptor signaling pathway | 3.7037 | 5 | yes |
GO:0060160 | negative regulation of dopamine receptor signaling pathway | 3.7037 | 6 | yes |
GO:0007270 | neuron-neuron synaptic transmission | 3.7037 | 8 | yes |
GO:0007405 | neuroblast proliferation | 3.7037 | 4 | yes |
GO:0090278 | negative regulation of peptide hormone secretion | 3.7037 | 6 | yes |
GO:0090325 | regulation of locomotion involved in locomotory behavior | 3.7037 | 4 | yes |
GO:0098801 | regulation of renal system process | 3.7037 | 5 | yes |
GO:0099170 | postsynaptic modulation of chemical synaptic transmission | 3.7037 | 6 | yes |
GO:1900037 | regulation of cellular response to hypoxia | 3.7037 | 5 | yes |
GO:1900038 | negative regulation of cellular response to hypoxia | 3.7037 | 5 | yes |
GO:1900166 | regulation of glial cell-derived neurotrophic factor production | 3.7037 | 5 | yes |
GO:1900168 | positive regulation of glial cell-derived neurotrophic factor production | 3.7037 | 6 | yes |
Disease
No data found.
Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
---|---|---|---|---|
CALM3_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
ARRB2_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
NTR1_HUMAN | [view interactions] | Low throughput | no | no |
OXYR_HUMAN | [view interactions] | Low throughput | no | no |
5HT2A_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
CNR1_HUMAN | [view interactions] | Low throughput | no | yes |
DRD2_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
DRD4_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
CLIC6_HUMAN | [view interactions] | Low throughput | no | no |
NCS1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
E41L1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
PAWR_HUMAN | [view interactions] | Low throughput | no | yes |
NFM_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
TRPC1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
CALM2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
CALM1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
KBTB7_HUMAN | [view interactions] | Low throughput | no | yes |
FLNA_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
KCNJ3_HUMAN | [view interactions] | Low throughput | no | yes |
KCNJ6_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
KCNJ5_HUMAN | [view interactions] | Low throughput | no | yes |
SH3G2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
DYN1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
GRIA2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
GRIA1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
NSF_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
KPCB_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
SSR2_HUMAN | [view interactions] | Low throughput | no | yes |
S39A1_HUMAN | [view interactions] | Low throughput | no | no |
S39A3_HUMAN | [view interactions] | Low throughput | no | yes |
OPRM_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
KBTB6_HUMAN | [view interactions] | Low throughput | no | yes |
MDM2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
CLH1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
CAV1_HUMAN | [view interactions] | Low throughput | no | no |
NCHL1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
TRPC4_HUMAN | [view interactions] | Low throughput | no | no |
TRPC5_HUMAN | [view interactions] | Low throughput | no | no |
HRH3_HUMAN | [view interactions] | Low throughput | no | no |
GNB5_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
NEB2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
DISC1_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
AA2AR_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
GP143_HUMAN | [view interactions] | Low throughput | no | yes |
SC6A3_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
DYN2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
DLG4_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
SH3K1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
DRD1_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
SGMR1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
GBB1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
TMM11_HUMAN | [view interactions] | High throughput | no | no |
CSCL1_HUMAN | [view interactions] | High throughput | no | no |
TEFF2_HUMAN | [view interactions] | High throughput | no | yes |
WFS1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
GNAI1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
ARRB1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
EGFR_HUMAN | [view interactions] | High throughput | no | no |
MSRA_HUMAN | [view interactions] | High throughput | no | no |
COL12_HUMAN | [view interactions] | High throughput | no | no |
WIPI4_HUMAN | [view interactions] | High throughput | no | no |
NFIP1_HUMAN | [view interactions] | High throughput | no | yes |
SNX4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
ANR28_HUMAN | [view interactions] | High throughput | no | no |
FACD2_HUMAN | [view interactions] | High throughput | no | no |
PP6R1_HUMAN | [view interactions] | High throughput | no | no |
SKP2_HUMAN | [view interactions] | High throughput | no | yes |
VDAC2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
GHITM_HUMAN | [view interactions] | High throughput | no | yes |
APH1A_HUMAN | [view interactions] | High throughput | no | yes |
RTN3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
LPAR1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
ZDHC4_HUMAN | [view interactions] | High throughput | no | no |
BAP29_HUMAN | [view interactions] | High throughput | no | yes |
SNG2_HUMAN | [view interactions] | High throughput | no | no |
CERS1_HUMAN | [view interactions] | High throughput | no | yes |
YIPF3_HUMAN | [view interactions] | High throughput | no | yes |
GASR_HUMAN | [view interactions] | High throughput | no | no |
AR6P6_HUMAN | [view interactions] | High throughput | no | yes |
S35B1_HUMAN | [view interactions] | High throughput | no | no |
TRAM1_HUMAN | [view interactions] | High throughput | no | yes |
S22AH_HUMAN | [view interactions] | High throughput | no | yes |
ABCA2_HUMAN | [view interactions] | High throughput | no | yes |
CLDN1_HUMAN | [view interactions] | High throughput | no | yes |
TTYH1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
GPR37_HUMAN | [view interactions] | High throughput | no | no |
WLS_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
GABR1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
B3A3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
CHPT1_HUMAN | [view interactions] | High throughput | no | yes |
BAP31_HUMAN | [view interactions] | High throughput | no | yes |
VATL_HUMAN | [view interactions] | High throughput | no | no |
ARL1_HUMAN | [view interactions] | High throughput | no | yes |
VPP2_HUMAN | [view interactions] | High throughput | no | yes |
LFG1_HUMAN | [view interactions] | High throughput | no | yes |
AGRB1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
G137A_HUMAN | [view interactions] | High throughput | no | no |
AGRG1_HUMAN | [view interactions] | High throughput | no | yes |
GABR2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
GDPD2_HUMAN | [view interactions] | High throughput | no | no |
CERS2_HUMAN | [view interactions] | High throughput | no | no |
NDUV1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
PIGG_HUMAN | [view interactions] | High throughput | no | yes |
PLLP_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
PLPR3_HUMAN | [view interactions] | High throughput | no | no |
PAQR6_HUMAN | [view interactions] | High throughput | no | no |
RTN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
RTN4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
RHBD2_HUMAN | [view interactions] | High throughput | no | yes |
OSTP_HUMAN | [view interactions] | High throughput | no | yes |
SERC3_HUMAN | [view interactions] | High throughput | no | yes |
S15A4_HUMAN | [view interactions] | High throughput | no | yes |
SC6A1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
TSN3_HUMAN | [view interactions] | High throughput | no | yes |
TSN7_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
SMIM7_HUMAN | [view interactions] | High throughput | no | yes |
CREL1_HUMAN | [view interactions] | High throughput | no | yes |
TRFE_HUMAN | [view interactions] | High throughput | no | no |
TM101_HUMAN | [view interactions] | High throughput | no | no |