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DRD2_HUMAN

GO
G2C
SynaptomeDB

Dopamine receptor whose activity is mediated by G proteins which inhibit adenylyl cyclase (PubMed). Positively regulates postnatal regression of retinal hyaloid vessels via suppression of VEGFR2/KDR activity, downstream of OPN5 . [View more on UniProt]

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No data found.

No annotated instance was found. To search for linear motifs, use the ELM prediction server.

Molecular function

Term Name % Distance from the top of the tree Annotated in DRD2_HUMAN
GO:0046872 metal ion binding 28.5714 4 no
GO:0001664 G protein-coupled receptor binding 22.2222 4 no
GO:0004930 G protein-coupled receptor activity 20.6349 4 yes
GO:0019900 kinase binding 20.6349 4 no
GO:0098960 postsynaptic neurotransmitter receptor activity 11.1111 4 yes
GO:0035254 glutamate receptor binding 9.5238 4 yes
GO:0035240 dopamine binding 7.9365 4 yes
GO:0004952 dopamine neurotransmitter receptor activity 6.3492 5 yes
GO:0015459 potassium channel regulator activity 6.3492 4 yes
GO:0035255 ionotropic glutamate receptor binding 6.3492 5 yes
GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go 4.7619 6 yes

Biological process

Term Name % Distance from top the of the tree Annotated in DRD2_HUMAN
GO:0048523 negative regulation of cellular process 65.0794 4 yes
GO:0010646 regulation of cell communication 61.9048 4 yes
GO:0048522 positive regulation of cellular process 58.7302 4 yes
GO:0031323 regulation of cellular metabolic process 50.7937 4 yes
GO:0051171 regulation of nitrogen compound metabolic process 50.7937 4 yes
GO:0080090 regulation of primary metabolic process 49.2063 4 yes
GO:0060255 regulation of macromolecule metabolic process 49.2063 4 yes
GO:0051049 regulation of transport 47.6190 4 yes
GO:0009966 regulation of signal transduction 47.6190 4 yes
GO:0009893 positive regulation of metabolic process 42.8571 4 yes
GO:0051246 regulation of protein metabolic process 41.2698 5 yes
GO:0023056 positive regulation of signaling 39.6825 4 yes
GO:0010647 positive regulation of cell communication 38.0952 5 yes
GO:0099177 regulation of trans-synaptic signaling 36.5079 4 yes
GO:1902531 regulation of intracellular signal transduction 36.5079 5 yes
GO:0050804 modulation of chemical synaptic transmission 36.5079 5 yes
GO:0043269 regulation of ion transport 34.9206 5 yes
GO:0051050 positive regulation of transport 34.9206 4 yes
GO:0031325 positive regulation of cellular metabolic process 33.3333 5 yes
GO:0048584 positive regulation of response to stimulus 33.3333 4 yes
GO:0051128 regulation of cellular component organization 33.3333 4 yes
GO:0009892 negative regulation of metabolic process 33.3333 4 yes
GO:0010605 negative regulation of macromolecule metabolic process 31.7460 5 yes
GO:0010648 negative regulation of cell communication 31.7460 5 yes
GO:0023057 negative regulation of signaling 31.7460 4 yes
GO:0051172 negative regulation of nitrogen compound metabolic process 31.7460 5 yes
GO:0009967 positive regulation of signal transduction 31.7460 5 yes
GO:0071702 organic substance transport 31.7460 4 yes
GO:0010604 positive regulation of macromolecule metabolic process 30.1587 5 yes
GO:0051046 regulation of secretion 30.1587 5 yes
GO:0006811 ion transport 30.1587 4 yes
GO:0008104 protein localization 30.1587 4 yes
GO:1903530 regulation of secretion by cell 28.5714 4 yes
GO:0031399 regulation of protein modification process 28.5714 6 yes
GO:0019220 regulation of phosphate metabolic process 26.9841 6 yes
GO:0031324 negative regulation of cellular metabolic process 26.9841 5 yes
GO:0042127 regulation of cell population proliferation 26.9841 4 yes
GO:0048585 negative regulation of response to stimulus 26.9841 4 yes
GO:0051173 positive regulation of nitrogen compound metabolic process 26.9841 5 yes
GO:0051174 regulation of phosphorus metabolic process 26.9841 5 yes
GO:0051248 negative regulation of protein metabolic process 26.9841 6 yes
GO:0010243 response to organonitrogen compound 26.9841 4 yes
GO:0010941 regulation of cell death 25.3968 4 yes
GO:0016192 vesicle-mediated transport 25.3968 4 yes
GO:1902533 positive regulation of intracellular signal transduction 25.3968 6 yes
GO:0043270 positive regulation of ion transport 25.3968 5 yes
GO:0009889 regulation of biosynthetic process 25.3968 4 yes
GO:0060627 regulation of vesicle-mediated transport 25.3968 4 yes
GO:0010468 regulation of gene expression 23.8095 5 yes
GO:0010959 regulation of metal ion transport 23.8095 6 yes
GO:0014070 response to organic cyclic compound 23.8095 4 yes
GO:0022607 cellular component assembly 23.8095 4 yes
GO:0030030 cell projection organization 23.8095 4 yes
GO:0042325 regulation of phosphorylation 23.8095 7 yes
GO:0043085 positive regulation of catalytic activity 23.8095 4 yes
GO:0001932 regulation of protein phosphorylation 23.8095 7 yes
GO:0051094 positive regulation of developmental process 23.8095 4 yes
GO:0051240 positive regulation of multicellular organismal process 23.8095 4 yes
GO:0051247 positive regulation of protein metabolic process 23.8095 6 yes
GO:0007188 adenylate cyclase-modulating G protein-coupled receptor signaling pathway 23.8095 4 yes
GO:0098916 anterograde trans-synaptic signaling 22.2222 5 yes
GO:0099537 trans-synaptic signaling 22.2222 4 yes
GO:0031326 regulation of cellular biosynthetic process 22.2222 5 yes
GO:0071705 nitrogen compound transport 22.2222 4 no
GO:0034762 regulation of transmembrane transport 22.2222 4 yes
GO:0051051 negative regulation of transport 22.2222 4 yes
GO:0006812 cation transport 22.2222 5 yes
GO:0007268 chemical synaptic transmission 22.2222 6 yes
GO:0030001 metal ion transport 20.6349 6 yes
GO:0042981 regulation of apoptotic process 20.6349 6 no
GO:0043067 regulation of programmed cell death 20.6349 5 no
GO:0006996 organelle organization 20.6349 4 no
GO:0032880 regulation of protein localization 20.6349 5 yes
GO:0034765 regulation of ion transmembrane transport 20.6349 5 yes
GO:0044057 regulation of system process 20.6349 4 yes
GO:0050890 cognition 20.6349 4 yes
GO:0051336 regulation of hydrolase activity 20.6349 4 yes
GO:0060341 regulation of cellular localization 20.6349 4 yes
GO:0009968 negative regulation of signal transduction 20.6349 5 yes
GO:0010562 positive regulation of phosphorus metabolic process 19.0476 6 yes
GO:1904062 regulation of cation transmembrane transport 19.0476 6 yes
GO:0031400 negative regulation of protein modification process 19.0476 7 yes
GO:0031401 positive regulation of protein modification process 19.0476 7 yes
GO:0045937 positive regulation of phosphate metabolic process 19.0476 7 yes
GO:0051130 positive regulation of cellular component organization 19.0476 5 yes
GO:0051924 regulation of calcium ion transport 19.0476 7 yes
GO:0010556 regulation of macromolecule biosynthetic process 17.4603 5 yes
GO:0017157 regulation of exocytosis 17.4603 5 yes
GO:0019219 regulation of nucleobase-containing compound metabolic process 17.4603 5 yes
GO:0022898 regulation of transmembrane transporter activity 17.4603 4 yes
GO:0032412 regulation of ion transmembrane transporter activity 17.4603 5 yes
GO:0042327 positive regulation of phosphorylation 17.4603 8 yes
GO:0043408 regulation of MAPK cascade 17.4603 6 yes
GO:0043410 positive regulation of MAPK cascade 17.4603 7 yes
GO:0045595 regulation of cell differentiation 17.4603 4 yes
GO:0051047 positive regulation of secretion 17.4603 5 yes
GO:0001934 positive regulation of protein phosphorylation 17.4603 8 yes
GO:0007193 adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway 17.4603 5 yes
GO:0060548 negative regulation of cell death 17.4603 5 yes
GO:0010563 negative regulation of phosphorus metabolic process 15.8730 6 yes
GO:1903305 regulation of regulated secretory pathway 15.8730 6 yes
GO:1903506 regulation of nucleic acid-templated transcription 15.8730 7 yes
GO:2001141 regulation of RNA biosynthetic process 15.8730 6 yes
GO:0032101 regulation of response to external stimulus 15.8730 4 yes
GO:0043549 regulation of kinase activity 15.8730 5 yes
GO:0045859 regulation of protein kinase activity 15.8730 6 yes
GO:0045936 negative regulation of phosphate metabolic process 15.8730 7 yes
GO:0048878 chemical homeostasis 15.8730 4 yes
GO:0051241 negative regulation of multicellular organismal process 15.8730 4 yes
GO:0051252 regulation of RNA metabolic process 15.8730 5 yes
GO:0006355 regulation of DNA-templated transcription 15.8730 6 yes
GO:0051338 regulation of transferase activity 15.8730 4 yes
GO:0006897 endocytosis 15.8730 5 yes
GO:0051726 regulation of cell cycle 15.8730 4 yes
GO:0008285 negative regulation of cell population proliferation 15.8730 5 yes
GO:0009891 positive regulation of biosynthetic process 15.8730 5 yes
GO:0010564 regulation of cell cycle process 14.2857 5 yes
GO:0080134 regulation of response to stress 14.2857 4 yes
GO:1903522 regulation of blood circulation 14.2857 5 yes
GO:1903532 positive regulation of secretion by cell 14.2857 5 yes
GO:2000026 regulation of multicellular organismal development 14.2857 4 yes
GO:0031328 positive regulation of cellular biosynthetic process 14.2857 6 yes
GO:2001257 regulation of cation channel activity 14.2857 6 yes
GO:0031623 receptor internalization 14.2857 7 yes
GO:0033674 positive regulation of kinase activity 14.2857 6 yes
GO:0043086 negative regulation of catalytic activity 14.2857 4 yes
GO:0043271 negative regulation of ion transport 14.2857 5 yes
GO:0045597 positive regulation of cell differentiation 14.2857 5 yes
GO:0045860 positive regulation of protein kinase activity 14.2857 7 yes
GO:0050805 negative regulation of synaptic transmission 14.2857 5 yes
GO:0051347 positive regulation of transferase activity 14.2857 5 yes
GO:0006898 receptor-mediated endocytosis 14.2857 6 yes
GO:0051588 regulation of neurotransmitter transport 14.2857 5 yes
GO:0051952 regulation of amine transport 14.2857 5 yes
GO:0008284 positive regulation of cell population proliferation 14.2857 5 yes
GO:0098655 cation transmembrane transport 12.6984 4 yes
GO:0098660 inorganic ion transmembrane transport 12.6984 4 yes
GO:0098662 inorganic cation transmembrane transport 12.6984 5 yes
GO:0098771 inorganic ion homeostasis 12.6984 6 yes
GO:1903169 regulation of calcium ion transmembrane transport 12.6984 7 yes
GO:0030003 cellular cation homeostasis 12.6984 5 yes
GO:0030100 regulation of endocytosis 12.6984 5 yes
GO:0030334 regulation of cell migration 12.6984 5 yes
GO:0031279 regulation of cyclase activity 12.6984 4 yes
GO:2000145 regulation of cell motility 12.6984 4 yes
GO:2000300 regulation of synaptic vesicle exocytosis 12.6984 5 yes
GO:0034763 negative regulation of transmembrane transport 12.6984 5 yes
GO:0042326 negative regulation of phosphorylation 12.6984 8 yes
GO:0043279 response to alkaloid 12.6984 5 yes
GO:0045761 regulation of adenylate cyclase activity 12.6984 5 yes
GO:0046903 secretion 12.6984 4 yes
GO:0046928 regulation of neurotransmitter secretion 12.6984 4 yes
GO:0048638 regulation of developmental growth 12.6984 4 yes
GO:0050801 ion homeostasis 12.6984 5 yes
GO:0001933 negative regulation of protein phosphorylation 12.6984 8 yes
GO:0051223 regulation of protein transport 12.6984 5 yes
GO:0051339 regulation of lyase activity 12.6984 4 yes
GO:0006820 anion transport 12.6984 5 yes
GO:0006873 cellular ion homeostasis 12.6984 4 yes
GO:0007189 adenylate cyclase-activating G protein-coupled receptor signaling pathway 12.6984 5 yes
GO:0051960 regulation of nervous system development 12.6984 5 yes
GO:0007613 memory 12.6984 4 yes
GO:0055080 cation homeostasis 12.6984 6 yes
GO:0008277 regulation of G protein-coupled receptor signaling pathway 12.6984 5 yes
GO:0060078 regulation of postsynaptic membrane potential 12.6984 4 yes
GO:0060284 regulation of cell development 12.6984 5 yes
GO:0070201 regulation of establishment of protein localization 12.6984 6 yes
GO:0010038 response to metal ion 12.6984 4 yes
GO:0072503 cellular divalent inorganic cation homeostasis 11.1111 6 yes
GO:0072507 divalent inorganic cation homeostasis 11.1111 7 yes
GO:0010720 positive regulation of cell development 11.1111 6 yes
GO:0010921 regulation of phosphatase activity 11.1111 5 yes
GO:0014075 response to amine 11.1111 5 yes
GO:0120039 plasma membrane bounded cell projection morphogenesis 11.1111 6 yes
GO:1901019 regulation of calcium ion transmembrane transporter activity 11.1111 6 yes
GO:1901020 negative regulation of calcium ion transmembrane transporter activity 11.1111 6 yes
GO:1903170 negative regulation of calcium ion transmembrane transport 11.1111 7 yes
GO:1903531 negative regulation of secretion by cell 11.1111 5 yes
GO:1904063 negative regulation of cation transmembrane transport 11.1111 7 yes
GO:2001258 negative regulation of cation channel activity 11.1111 6 yes
GO:0032102 negative regulation of response to external stimulus 11.1111 5 yes
GO:0032410 negative regulation of transporter activity 11.1111 4 yes
GO:0032413 negative regulation of ion transmembrane transporter activity 11.1111 5 yes
GO:0032990 cell part morphogenesis 11.1111 4 yes
GO:0034766 negative regulation of ion transmembrane transport 11.1111 6 yes
GO:0035303 regulation of dephosphorylation 11.1111 7 yes
GO:0035304 regulation of protein dephosphorylation 11.1111 7 yes
GO:0043666 regulation of phosphoprotein phosphatase activity 11.1111 6 yes
GO:0048259 regulation of receptor-mediated endocytosis 11.1111 6 yes
GO:0048812 neuron projection morphogenesis 11.1111 7 yes
GO:0048858 cell projection morphogenesis 11.1111 5 yes
GO:0050708 regulation of protein secretion 11.1111 5 yes
GO:0050806 positive regulation of synaptic transmission 11.1111 5 yes
GO:0051048 negative regulation of secretion 11.1111 5 yes
GO:0001975 response to amphetamine 11.1111 6 yes
GO:0051282 regulation of sequestering of calcium ion 11.1111 4 yes
GO:0006874 cellular calcium ion homeostasis 11.1111 7 yes
GO:0006875 cellular metal ion homeostasis 11.1111 6 yes
GO:0007200 phospholipase C-activating G protein-coupled receptor signaling pathway 11.1111 4 yes
GO:0051926 negative regulation of calcium ion transport 11.1111 6 yes
GO:0007600 sensory perception 11.1111 4 yes
GO:0051954 positive regulation of amine transport 11.1111 5 yes
GO:0007612 learning 11.1111 4 yes
GO:0051962 positive regulation of nervous system development 11.1111 5 yes
GO:0051966 regulation of synaptic transmission, glutamatergic 11.1111 6 yes
GO:0055065 metal ion homeostasis 11.1111 7 yes
GO:0008016 regulation of heart contraction 11.1111 6 yes
GO:0055074 calcium ion homeostasis 11.1111 8 yes
GO:0060079 excitatory postsynaptic potential 11.1111 5 yes
GO:0070372 regulation of ERK1 and ERK2 cascade 11.1111 7 yes
GO:0070374 positive regulation of ERK1 and ERK2 cascade 11.1111 8 yes
GO:0010628 positive regulation of gene expression 9.5238 6 yes
GO:0015711 organic anion transport 9.5238 5 yes
GO:0015849 organic acid transport 9.5238 5 yes
GO:0018958 phenol-containing compound metabolic process 9.5238 4 yes
GO:1901385 regulation of voltage-gated calcium channel activity 9.5238 7 yes
GO:1901386 negative regulation of voltage-gated calcium channel activity 9.5238 7 yes
GO:1902532 negative regulation of intracellular signal transduction 9.5238 6 yes
GO:1903828 negative regulation of protein localization 9.5238 5 yes
GO:0031280 negative regulation of cyclase activity 9.5238 5 yes
GO:0031347 regulation of defense response 9.5238 5 yes
GO:0032465 regulation of cytokinesis 9.5238 5 yes
GO:0034330 cell junction organization 9.5238 4 yes
GO:0040013 negative regulation of locomotion 9.5238 4 yes
GO:0042220 response to cocaine 9.5238 4 yes
GO:0042417 dopamine metabolic process 9.5238 7 yes
GO:0043266 regulation of potassium ion transport 9.5238 7 yes
GO:0044106 cellular amine metabolic process 9.5238 4 yes
GO:0045927 positive regulation of growth 9.5238 4 yes
GO:0045935 positive regulation of nucleobase-containing compound metabolic process 9.5238 6 yes
GO:0050433 regulation of catecholamine secretion 9.5238 5 yes
GO:0050767 regulation of neurogenesis 9.5238 6 yes
GO:0050776 regulation of immune response 9.5238 4 yes
GO:0050807 regulation of synapse organization 9.5238 5 yes
GO:0050808 synapse organization 9.5238 5 yes
GO:0001817 regulation of cytokine production 9.5238 4 yes
GO:0002090 regulation of receptor internalization 9.5238 7 yes
GO:0006576 cellular biogenic amine metabolic process 9.5238 5 yes
GO:0006584 catecholamine metabolic process 9.5238 6 yes
GO:0051302 regulation of cell division 9.5238 4 yes
GO:0006869 lipid transport 9.5238 5 yes
GO:0051350 negative regulation of lyase activity 9.5238 5 yes
GO:0007194 negative regulation of adenylate cyclase activity 9.5238 6 yes
GO:0008344 adult locomotory behavior 9.5238 4 yes
GO:0009308 amine metabolic process 9.5238 4 yes
GO:0009712 catechol-containing compound metabolic process 9.5238 5 yes
GO:0010557 positive regulation of macromolecule biosynthetic process 7.9365 6 yes
GO:0021885 forebrain cell migration 7.9365 4 yes
GO:0022029 telencephalon cell migration 7.9365 5 yes
GO:1904950 negative regulation of establishment of protein localization 7.9365 6 yes
GO:2000177 regulation of neural precursor cell proliferation 7.9365 5 yes
GO:0031348 negative regulation of defense response 7.9365 5 yes
GO:0045807 positive regulation of endocytosis 7.9365 5 yes
GO:0046883 regulation of hormone secretion 7.9365 4 yes
GO:0046887 positive regulation of hormone secretion 7.9365 5 yes
GO:0046942 carboxylic acid transport 7.9365 6 yes
GO:0048148 behavioral response to cocaine 7.9365 4 yes
GO:0048168 regulation of neuronal synaptic plasticity 7.9365 4 yes
GO:0048260 positive regulation of receptor-mediated endocytosis 7.9365 6 yes
GO:0048639 positive regulation of developmental growth 7.9365 5 yes
GO:0050709 negative regulation of protein secretion 7.9365 6 yes
GO:0050769 positive regulation of neurogenesis 7.9365 6 yes
GO:0050795 regulation of behavior 7.9365 4 yes
GO:0001764 neuron migration 7.9365 4 yes
GO:0002031 G protein-coupled receptor internalization 7.9365 8 yes
GO:0051224 negative regulation of protein transport 7.9365 5 yes
GO:0006357 regulation of transcription by RNA polymerase II 7.9365 7 yes
GO:0006816 calcium ion transport 7.9365 7 yes
GO:0006936 muscle contraction 7.9365 4 yes
GO:0060134 prepulse inhibition 7.9365 6 yes
GO:0009416 response to light stimulus 7.9365 4 yes
GO:0090087 regulation of peptide transport 6.3492 5 yes
GO:0090276 regulation of peptide hormone secretion 6.3492 5 yes
GO:0090277 positive regulation of peptide hormone secretion 6.3492 6 yes
GO:0090659 walking behavior 6.3492 4 yes
GO:0097553 calcium ion transmembrane import into cytosol 6.3492 7 yes
GO:0014059 regulation of dopamine secretion 6.3492 6 yes
GO:0098801 regulation of renal system process 6.3492 5 yes
GO:0099170 postsynaptic modulation of chemical synaptic transmission 6.3492 6 yes
GO:0015908 fatty acid transport 6.3492 6 yes
GO:0015909 long-chain fatty acid transport 6.3492 7 yes
GO:0016055 Wnt signaling pathway 6.3492 5 yes
GO:1902680 positive regulation of RNA biosynthetic process 6.3492 7 yes
GO:1903508 positive regulation of nucleic acid-templated transcription 6.3492 8 yes
GO:1905114 cell surface receptor signaling pathway involved in cell-cell signaling 6.3492 4 yes
GO:2000179 positive regulation of neural precursor cell proliferation 6.3492 6 yes
GO:0032228 regulation of synaptic transmission, GABAergic 6.3492 6 yes
GO:0035809 regulation of urine volume 6.3492 4 yes
GO:0035810 positive regulation of urine volume 6.3492 5 yes
GO:0035813 regulation of renal sodium excretion 6.3492 6 yes
GO:0035815 positive regulation of renal sodium excretion 6.3492 5 yes
GO:0036293 response to decreased oxygen levels 6.3492 4 yes
GO:0040014 regulation of multicellular organism growth 6.3492 4 yes
GO:0040018 positive regulation of multicellular organism growth 6.3492 5 yes
GO:0042749 regulation of circadian sleep/wake cycle 6.3492 4 yes
GO:0044062 regulation of excretion 6.3492 5 yes
GO:0045187 regulation of circadian sleep/wake cycle, sleep 6.3492 5 yes
GO:0045787 positive regulation of cell cycle 6.3492 5 yes
GO:0045893 positive regulation of DNA-templated transcription 6.3492 7 yes
GO:0048149 behavioral response to ethanol 6.3492 4 yes
GO:0048169 regulation of long-term neuronal synaptic plasticity 6.3492 5 yes
GO:0002028 regulation of sodium ion transport 6.3492 7 yes
GO:0002092 positive regulation of receptor internalization 6.3492 7 yes
GO:0002683 negative regulation of immune system process 6.3492 4 yes
GO:0002791 regulation of peptide secretion 6.3492 6 yes
GO:0002793 positive regulation of peptide secretion 6.3492 6 yes
GO:0002831 regulation of response to biotic stimulus 6.3492 4 yes
GO:0051254 positive regulation of RNA metabolic process 6.3492 6 yes
GO:0051482 positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway 6.3492 4 yes
GO:0051580 regulation of neurotransmitter uptake 6.3492 4 yes
GO:0051584 regulation of dopamine uptake involved in synaptic transmission 6.3492 6 yes
GO:0006939 smooth muscle contraction 6.3492 5 yes
GO:0051590 positive regulation of neurotransmitter transport 6.3492 5 yes
GO:0051896 regulation of protein kinase B signaling 6.3492 6 yes
GO:0007195 adenylate cyclase-inhibiting dopamine receptor signaling pathway 6.3492 4 yes
GO:0051940 regulation of catecholamine uptake involved in synaptic transmission 6.3492 5 yes
GO:0007409 axonogenesis 6.3492 8 yes
GO:0007606 sensory perception of chemical stimulus 6.3492 5 yes
GO:0007628 adult walking behavior 6.3492 5 yes
GO:0060123 regulation of growth hormone secretion 6.3492 6 yes
GO:0008306 associative learning 6.3492 5 yes
GO:0060124 positive regulation of growth hormone secretion 6.3492 7 yes
GO:0070588 calcium ion transmembrane transport 6.3492 6 yes
GO:0071875 adrenergic receptor signaling pathway 4.7619 4 yes
GO:0071880 adenylate cyclase-activating adrenergic receptor signaling pathway 4.7619 5 yes
GO:0090068 positive regulation of cell cycle process 4.7619 6 yes
GO:0090278 negative regulation of peptide hormone secretion 4.7619 6 yes
GO:0014072 response to isoquinoline alkaloid 4.7619 5 yes
GO:0014821 phasic smooth muscle contraction 4.7619 6 yes
GO:0015718 monocarboxylic acid transport 4.7619 7 yes
GO:1900271 regulation of long-term synaptic potentiation 4.7619 4 yes
GO:1900273 positive regulation of long-term synaptic potentiation 4.7619 5 yes
GO:0021826 substrate-independent telencephalic tangential migration 4.7619 6 yes
GO:0021830 interneuron migration from the subpallium to the cortex 4.7619 8 yes
GO:0021843 substrate-independent telencephalic tangential interneuron migration 4.7619 7 yes
GO:0021853 cerebral cortex GABAergic interneuron migration 4.7619 6 yes
GO:1902692 regulation of neuroblast proliferation 4.7619 6 yes
GO:0030336 negative regulation of cell migration 4.7619 6 yes
GO:1903963 arachidonate transport 4.7619 8 yes
GO:0030432 peristalsis 4.7619 7 yes
GO:1904936 interneuron migration 4.7619 5 yes
GO:2000146 negative regulation of cell motility 4.7619 5 yes
GO:0032309 icosanoid secretion 4.7619 5 yes
GO:0032467 positive regulation of cytokinesis 4.7619 6 yes
GO:0033602 negative regulation of dopamine secretion 4.7619 6 yes
GO:0033604 negative regulation of catecholamine secretion 4.7619 6 yes
GO:0034329 cell junction assembly 4.7619 5 yes
GO:0034776 response to histamine 4.7619 5 yes
GO:0042321 negative regulation of circadian sleep/wake cycle, sleep 4.7619 5 yes
GO:0042754 negative regulation of circadian rhythm 4.7619 4 yes
GO:0043278 response to morphine 4.7619 6 yes
GO:0045088 regulation of innate immune response 4.7619 5 yes
GO:0045824 negative regulation of innate immune response 4.7619 6 yes
GO:0045944 positive regulation of transcription by RNA polymerase II 4.7619 8 yes
GO:0046676 negative regulation of insulin secretion 4.7619 7 yes
GO:0046717 acid secretion 4.7619 5 yes
GO:0046888 negative regulation of hormone secretion 4.7619 5 yes
GO:0048521 negative regulation of behavior 4.7619 5 yes
GO:0050482 arachidonic acid secretion 4.7619 6 yes
GO:0050777 negative regulation of immune response 4.7619 5 yes
GO:0050796 regulation of insulin secretion 4.7619 6 yes
GO:0001819 positive regulation of cytokine production 4.7619 5 yes
GO:0002052 positive regulation of neuroblast proliferation 4.7619 7 yes
GO:0051209 release of sequestered calcium ion into cytosol 4.7619 6 yes
GO:0002792 negative regulation of peptide secretion 4.7619 6 yes
GO:0002832 negative regulation of response to biotic stimulus 4.7619 5 yes
GO:0051283 negative regulation of sequestering of calcium ion 4.7619 5 yes
GO:0051582 positive regulation of neurotransmitter uptake 4.7619 5 yes
GO:0051586 positive regulation of dopamine uptake involved in synaptic transmission 4.7619 6 yes
GO:0051781 positive regulation of cell division 4.7619 5 yes
GO:0051898 negative regulation of protein kinase B signaling 4.7619 7 yes
GO:0051944 positive regulation of catecholamine uptake involved in synaptic transmission 4.7619 6 yes
GO:0007416 synapse assembly 4.7619 6 yes
GO:0051953 negative regulation of amine transport 4.7619 5 yes
GO:0007608 sensory perception of smell 4.7619 6 yes
GO:0007616 long-term memory 4.7619 5 yes
GO:0051967 negative regulation of synaptic transmission, glutamatergic 4.7619 6 yes
GO:0008542 visual learning 4.7619 4 yes
GO:0060158 phospholipase C-activating dopamine receptor signaling pathway 4.7619 4 yes
GO:0010039 response to iron ion 4.7619 5 yes
GO:0071715 icosanoid transport 4.7619 7 yes
GO:0090325 regulation of locomotion involved in locomotory behavior 3.1746 4 yes
GO:1900166 regulation of glial cell-derived neurotrophic factor production 3.1746 5 yes
GO:1900168 positive regulation of glial cell-derived neurotrophic factor production 3.1746 6 yes
GO:0031223 auditory behavior 3.1746 4 yes
GO:0032147 activation of protein kinase activity 3.1746 8 yes
GO:0042756 drinking behavior 3.1746 4 yes
GO:0045745 positive regulation of G protein-coupled receptor signaling pathway 3.1746 6 yes
GO:0045776 negative regulation of blood pressure 3.1746 4 yes
GO:0048678 response to axon injury 3.1746 4 yes
GO:0001976 nervous system process involved in regulation of systemic arterial blood pressure 3.1746 4 yes
GO:0051823 regulation of synapse structural plasticity 3.1746 6 yes
GO:0007270 neuron-neuron synaptic transmission 3.1746 7 yes
GO:0060159 regulation of dopamine receptor signaling pathway 3.1746 5 yes
GO:0060160 negative regulation of dopamine receptor signaling pathway 3.1746 6 yes

Disease

Term Name % Distance from top the of the tree Annotated in DRD2_HUMAN
DOID:114 heart disease 4.7619 3 no
DOID:0050700 cardiomyopathy 3.1746 4 no
DOID:0060036 intrinsic cardiomyopathy 3.1746 5 no
DOID:2843 long QT syndrome 3.1746 6 no
Uniprot ID Details Highest evidence Localizing into PSD HPA (protein expression in neurons)
PAWR_HUMAN [view interactions] Low throughput no yes
NFM_HUMAN [view entry] [view interactions] Low throughput yes yes
TRPC1_HUMAN [view interactions] Low throughput no yes
KBTB7_HUMAN [view interactions] Low throughput no yes
FLNA_HUMAN [view entry] [view interactions] Low throughput yes no
KCNJ3_HUMAN [view interactions] Low throughput no yes
KCNJ6_HUMAN [view interactions] Low throughput no no
KCNJ5_HUMAN [view interactions] Low throughput no yes
SH3G2_HUMAN [view entry] [view interactions] Low throughput yes yes
DYN1_HUMAN [view entry] [view interactions] Low throughput yes yes
GRIA2_HUMAN [view entry] [view interactions] Low throughput yes yes
GRIA1_HUMAN [view entry] [view interactions] Low throughput yes yes
NSF_HUMAN [view entry] [view interactions] Low throughput yes yes
KPCB_HUMAN [view entry] [view interactions] Low throughput yes yes
SSR2_HUMAN [view interactions] Low throughput no yes
S39A1_HUMAN [view interactions] Low throughput no no
S39A3_HUMAN [view interactions] Low throughput no yes
OPRM_HUMAN [view entry] [view interactions] Low throughput yes no
KBTB6_HUMAN [view interactions] Low throughput no yes
MDM2_HUMAN [view interactions] Low throughput no yes
CLH1_HUMAN [view entry] [view interactions] Low throughput yes yes
CAV1_HUMAN [view interactions] Low throughput no no
NCHL1_HUMAN [view entry] [view interactions] Low throughput yes yes
TRPC4_HUMAN [view interactions] Low throughput no no
TRPC5_HUMAN [view interactions] Low throughput no no
HRH3_HUMAN [view interactions] Low throughput no no
GNB5_HUMAN [view entry] [view interactions] Low throughput yes yes
NEB2_HUMAN [view entry] [view interactions] Low throughput yes yes
DISC1_HUMAN [view entry] [view interactions] Low throughput yes no
AA2AR_HUMAN [view entry] [view interactions] Low throughput yes yes
GP143_HUMAN [view interactions] Low throughput no yes
SC6A3_HUMAN [view entry] [view interactions] Low throughput yes yes
DLG4_HUMAN [view entry] [view interactions] Low throughput yes yes
DYN2_HUMAN [view entry] [view interactions] Low throughput yes yes
SH3K1_HUMAN [view entry] [view interactions] Low throughput yes yes
DRD1_HUMAN [view entry] [view interactions] Low throughput yes no
SGMR1_HUMAN [view entry] [view interactions] Low throughput yes yes
GBB1_HUMAN [view entry] [view interactions] Low throughput yes yes
CALM2_HUMAN [view entry] [view interactions] Low throughput yes yes
CALM3_HUMAN [view entry] [view interactions] Low throughput yes yes
CALM1_HUMAN [view entry] [view interactions] Low throughput yes yes
ARRB2_HUMAN [view entry] [view interactions] Low throughput yes no
NTR1_HUMAN [view interactions] Low throughput no no
OXYR_HUMAN [view interactions] Low throughput no no
5HT2A_HUMAN [view entry] [view interactions] Low throughput yes yes
CNR1_HUMAN [view interactions] Low throughput no yes
DRD2_HUMAN [view entry] [view interactions] Low throughput yes no
DRD4_HUMAN [view entry] [view interactions] Low throughput yes no
CLIC6_HUMAN [view interactions] Low throughput no no
NCS1_HUMAN [view entry] [view interactions] Low throughput yes yes
E41L1_HUMAN [view entry] [view interactions] Low throughput yes yes
EGFR_HUMAN [view interactions] High throughput no no
MSRA_HUMAN [view interactions] High throughput no no
COL12_HUMAN [view interactions] High throughput no no
WIPI4_HUMAN [view interactions] High throughput no no
NFIP1_HUMAN [view interactions] High throughput no yes
SNX4_HUMAN [view entry] [view interactions] High throughput yes yes
ANR28_HUMAN [view interactions] High throughput no no
FACD2_HUMAN [view interactions] High throughput no no
PP6R1_HUMAN [view interactions] High throughput no no
SKP2_HUMAN [view interactions] High throughput no yes
VDAC2_HUMAN [view entry] [view interactions] High throughput yes yes
APH1A_HUMAN [view interactions] High throughput no yes
GHITM_HUMAN [view interactions] High throughput no yes
RTN3_HUMAN [view entry] [view interactions] High throughput yes yes
LPAR1_HUMAN [view entry] [view interactions] High throughput yes no
BAP29_HUMAN [view interactions] High throughput no yes
SNG2_HUMAN [view interactions] High throughput no no
TRAM1_HUMAN [view interactions] High throughput no yes
YIPF3_HUMAN [view interactions] High throughput no yes
CERS1_HUMAN [view interactions] High throughput no yes
S35B1_HUMAN [view interactions] High throughput no no
ZDHC4_HUMAN [view interactions] High throughput no no
GASR_HUMAN [view interactions] High throughput no no
AR6P6_HUMAN [view interactions] High throughput no yes
CLDN1_HUMAN [view interactions] High throughput no yes
ABCA2_HUMAN [view interactions] High throughput no yes
S22AH_HUMAN [view interactions] High throughput no yes
TTYH1_HUMAN [view entry] [view interactions] High throughput yes no
WLS_HUMAN [view entry] [view interactions] High throughput yes no
GABR1_HUMAN [view entry] [view interactions] High throughput yes yes
B3A3_HUMAN [view entry] [view interactions] High throughput yes no
LFG1_HUMAN [view interactions] High throughput no yes
VPP2_HUMAN [view interactions] High throughput no yes
ARL1_HUMAN [view interactions] High throughput no yes
VATL_HUMAN [view interactions] High throughput no no
BAP31_HUMAN [view interactions] High throughput no yes
AGRB1_HUMAN [view entry] [view interactions] High throughput yes no
CHPT1_HUMAN [view interactions] High throughput no yes
GPR37_HUMAN [view interactions] High throughput no no
CREL1_HUMAN [view interactions] High throughput no yes
SMIM7_HUMAN [view interactions] High throughput no yes
AGRG1_HUMAN [view interactions] High throughput no yes
GABR2_HUMAN [view entry] [view interactions] High throughput yes yes
GDPD2_HUMAN [view interactions] High throughput no no
CERS2_HUMAN [view interactions] High throughput no no
NDUV1_HUMAN [view entry] [view interactions] High throughput yes yes
PIGG_HUMAN [view interactions] High throughput no yes
PLLP_HUMAN [view entry] [view interactions] High throughput yes no
PLPR3_HUMAN [view interactions] High throughput no no
PAQR6_HUMAN [view interactions] High throughput no no
RTN1_HUMAN [view entry] [view interactions] High throughput yes yes
RTN4_HUMAN [view entry] [view interactions] High throughput yes yes
RHBD2_HUMAN [view interactions] High throughput no yes
OSTP_HUMAN [view interactions] High throughput no yes
SERC3_HUMAN [view interactions] High throughput no yes
S15A4_HUMAN [view interactions] High throughput no yes
SC6A1_HUMAN [view entry] [view interactions] High throughput yes no
TSN3_HUMAN [view interactions] High throughput no yes
TSN7_HUMAN [view entry] [view interactions] High throughput yes yes
G137A_HUMAN [view interactions] High throughput no no
TM101_HUMAN [view interactions] High throughput no no
CSCL1_HUMAN [view interactions] High throughput no no
TRFE_HUMAN [view interactions] High throughput no no
TMM11_HUMAN [view interactions] High throughput no no
TEFF2_HUMAN [view interactions] High throughput no yes
WFS1_HUMAN [view entry] [view interactions] High throughput yes yes
GNAI1_HUMAN [view entry] [view interactions] High throughput yes yes
ARRB1_HUMAN [view entry] [view interactions] High throughput yes yes
GIPC1_HUMAN [view entry] [view interactions] Computational yes yes
GRM5_HUMAN [view entry] [view interactions] Computational yes no
TY3H_HUMAN [view interactions] Computational no no
NEU1_HUMAN [view interactions] Computational no no
COMT_HUMAN [view entry] [view interactions] Computational yes yes
ARRS_HUMAN [view interactions] Computational no no
GNAI2_HUMAN [view entry] [view interactions] Computational yes yes
ANKK1_HUMAN [view interactions] Computational no no
S100B_HUMAN [view entry] [view interactions] Computational yes yes
SMS_HUMAN [view entry] [view interactions] Computational yes no
ARBK1_HUMAN [view entry] [view interactions] Computational yes yes
GNAI3_HUMAN [view entry] [view interactions] Computational yes yes
NMDE2_HUMAN [view entry] [view interactions] Computational yes no
GHRL_HUMAN [view entry] [view interactions] Computational yes no
NPY_HUMAN [view interactions] Computational no yes
SC6A4_HUMAN [view entry] [view interactions] Computational yes no
FABPH_HUMAN [view entry] [view interactions] Computational yes no